D. Blow

发表

Structure of tyrosyl-tRNA synthetase refined at 2.3 A resolution. Interaction of the enzyme with the tyrosyl adenylate intermediate.

P. Brick, T. Bhat, D. Blow, 1989, Journal of molecular biology.

The Structure of haemoglobin - VII. Determination of phase angles in the non-centrosymmetric [100] zone

D. Blow, 1958, Proceedings of the Royal Society of London. Series A. Mathematical and Physical Sciences.

The treatment of errors in the isomorphous replacement method

F. Crick, D. Blow, 1959 .

The detection of sub‐units within the crystallographic asymmetric unit

D. Blow, M. Rossmann, 1962 .

Determination of phases by the conditions of non-crystallographic symmetry

D. Blow, M. Rossmann, 1963 .

Hydrogen bonding and biological specificity analysed by protein engineering

A. Fersht, M. Waye, P. Brick, 1985, Nature.

An Automated System for Micro-Batch Protein Crystallization and Screening

D. Blow, N. Chayen, P. D. Stewart, 1990 .

Role of a Buried Acid Group in the Mechanism of Action of Chymotrypsin

D. Blow, J. Birktoft, B. Hartley, 1969, Nature.

More of the catalytic triad

D. Blow, 1990, Nature.

Structure of crystalline alpha-chymotrypsin. 3. Crystallographic studies of substrates and inhibitors bound to the active site of alpha-chymotrypsin.

R Henderson, T. Steitz, R. Henderson, 1969, Journal of molecular biology.

Control of nucleation in the crystallization of lysozyme

N E Chayen, D. Blow, N. Chayen, 1993, Protein science : a publication of the Protein Society.

Microbatch crystallization under oil — a new technique allowing many small-volume crystallization trials

David M. Blow, Naomi E. Chayen, D. Blow, 1992 .

Many crystal forms of human immunodeficiency virus reverse transcriptase.

P. Brick, D. Blow, N. Chayen, 1991, Journal of molecular biology.

Phase diagram and dilution experiments in the crystallization of carboxypeptidase G2.

D. Blow, E. Saridakis, P. D. Stewart, 1994, Acta crystallographica. Section D, Biological crystallography.

Structure of crystalline -chymotrypsin. V. The atomic structure of tosyl- -chymotrypsin at 2 A resolution.

D. M. Blow, D. Blow, J. Birktoft, 1972, Journal of molecular biology.

Structure of crystalline methyl-chymotrypsin.

D. Blow, C. Wright, G. P. Hess, 1972, Journal of molecular biology.

Outline of Crystallography for Biologists

David Blow, D. Blow, 2002 .

Formation of a Helical Steroid Complex

A. Rich, D. Blow, DAVID M. BLOW, 1958, Nature.

A model for the association of bovine pancreatic trypsin inhibitor with chymotrypsin and trypsin.

R. Huber, D. Blow, D. Kukla, 1972, Journal of molecular biology.

Molecular structure: Computer cues to combat hypertension

D. Blow, 1983, Nature.

Stereochemistry of Substrate Binding and Hydrolysis in the Trypsin Family of Enzymes

D. Blow, 1974 .

Leaving group specificity in the chymotrypsin-catalyzed hydrolysis of peptides. A stereochemical interpretation.

A. Fersht, D. Blow, J. Fastrez, 1973, Biochemistry.

The Laue rapid diffraction technique reveals an ordered water molecule poised to attack the acyl group of an acyl-trypsin analogue of the intermediate in trypsin-catalysed reactions.

D. Blow, 1993 .

Now you see it, now you don't

D. Blow, 1993, Current Biology.

Solubility of glucose isomerase in ammonium sulphate solutions

D. Blow, N. Chayen, S. Campbell-Smith, 1988 .

Structure and mechanism of chymotrypsin

David M. Blow, D. Blow, 1976 .

Enzyme substrate and inhibitor interactions.

D. Blow, J. M. Smith, 1975, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Structure and mechanism of D-xylose isomerase.

D. Blow, O. Smart, C. Collyer, 1992, Faraday discussions.

Crystallogenesis studies in microgravity with the Advanced Protein Crystallization Facility on SpaceHab-01

B. Lorber, D. Blow, R. Giegé, 1997 .

The tortuous story of Asp ... His ... Ser: structural analysis of alpha-chymotrypsin.

D. Blow, 1997, Trends in biochemical sciences.

Structure of the Kunitz-type soybean trypsin inhibitor (STI): implication for the interactions between members of the STI family and tissue-plasminogen activator.

P. Brick, D. Blow, S. Onesti, 1998, Acta crystallographica. Section D, Biological crystallography.

The crystallization of glucose isomerase from Arthrobacter B3728

P. Brick, D. Blow, P. Shaw, 1986 .

Letter: Crystallization and preliminary x-ray diffraction studies on tyrosyl-transfer RNA synthetase from Bacillus stearothermophilus.

D. Blow, B. Reid, B. Hartley, 1973, Journal of molecular biology.

The single isomorphous replacement method. A correction

D. Blow, M. Rossmann, 1962 .

The Role of Separate Domains and of Individual Amino-Acids in Enzyme Catalysis, Studied by Site-Directed Mutagenesis

A. Fersht, P. Brick, D. Blow, 1987 .

Structure of crystalline -chymotrypsin. II. A preliminary report including a hypothesis for the activation mechanism.

B. Matthews, R. Henderson, D. Blow, 1968, Journal of molecular biology.

Three-dimensional Structure of Tosyl-α-chymotrypsin

B. Matthews, R. Henderson, D. Blow, 1967, Nature.

To fit a plane to a set of points by least squares

D. M. Blow, D. Blow, 1960 .

Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed by a 1,2-hydride shift.

D. Blow, K. Henrick, C. Collyer, 1993, Journal of molecular biology.

Crystal structure of carboxypeptidase G2, a bacterial enzyme with applications in cancer therapy.

P. Brick, D. Blow, R. Pauptit, 1997, Structure.

Crystal structure of cholesterol oxidase from Brevibacterium sterolicum refined at 1.8 A resolution.

D. Blow, A. Vrielink, L. F. Lloyd, 1991, Journal of molecular biology.

Crystal structure of a Kunitz-type trypsin inhibitor from Erythrina caffra seeds.

P. Brick, D. Blow, S. Onesti, 1991, Journal of molecular biology.

Structures of D-xylose isomerase from Arthrobacter strain B3728 containing the inhibitors xylitol and D-sorbitol at 2.5 A and 2.3 A resolution, respectively.

D. Blow, K. Henrick, C. Collyer, 1990, Journal of molecular biology.

Crystal structure of a deletion mutant of a tyrosyl-tRNA synthetase complexed with tyrosine.

P. Brick, D. Blow, David M. Blow, 1987, Journal of molecular biology.

6 The Structure of Chymotrypsin

D. M. Blow, D. Blow, 1971 .

X-ray diffraction studies of enzymes.

T. Steitz, D. Blow, 1970, Annual review of biochemistry.

Analysis of Enzyme Structure and Activity by Protein Engineering

Alan R. Fersht, David M. Blow, Anthony J. Wilkinson, 1984 .

Studies on the Formation of Helical Deoxycholate Complexes1,2

A. Rich, D. Blow, 1960 .

-Chymotrypsin: what can we learn about catalysis from x-ray diffraction?

R. Henderson, D. Blow, C. Wright, 1972, Cold Spring Harbor symposia on quantitative biology.

The Structure of $\alpha$ -Chymotrypsin

T. Steitz, R. Henderson, D. Blow, 1970 .

Observations of reaction intermediates and the mechanism of aldose-ketose interconversion by D-xylose isomerase.

D. Blow, C. Collyer, C A Collyer, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Anomeric specificity of D-xylose isomerase.

D. Blow, G. Fleet, C. Collyer, 1992, Biochemistry.

Structure of crystalline α-chymotrypsin: III. Crystallographic studies of substrates and inhibitors bound to the active site of α-chymotrypsin

Thomas A. Steitz, D. M. Blow, T. Steitz, 1969 .

Structure of alpha-chymotrypsin refined at 1.68 A resolution.

D. Blow, D M Blow, H Tsukada, 1985, Journal of molecular biology.

Crystal structure of the complex of porcine trypsin with soybean trypsin inhibitor (Kunitz) at 2.6-A resolution.

R M Sweet, C. Chothia, J. Janin, 1974, Biochemistry.

Crystal structure of cholesterol oxidase complexed with a steroid substrate: implications for flavin adenine dinucleotide dependent alcohol oxidases.

P. Brick, D. Blow, A. Vrielink, 1993, Biochemistry.

General Discussion Remark: Energetics of Inhibitor Binding

D. Blow, 1974 .

SOYBEAN TRYPSIN INHIBITOR

P. Brick, D. Blow, S. Onesti, 1998 .

Trigonal crystals of glucose isomerase require thymol for their growth and stability

D. Blow, N. Chayen, C. Collyer, 1989 .

A large increase in enzyme–substrate affinity by protein engineering

A. Fersht, D. Blow, G. Winter, 1984, Nature.

A novel spin filter method for the measurement of solubility

D. Blow, L. Haire, 2001 .

Crystallization studies on HIV-1 reverse transcriptase

P. Brick, D. Blow, L. F. Lloyd, 1992 .

Comparison of backbone structures of glucose isomerase from Streptomyces and Arthrobacter.

H L Carrell, J P Glusker, H. L. Carrell, 1988, Protein engineering.

An X-ray diffraction study of inhibited derivatives of α-chymotrypsin

B. Matthews, D. Blow, P. Sigler, 1966 .

Structural homology in the amino-terminal domains of two aminoacyl-tRNA synthetases.

T. Bhat, D. Blow, J. Risler, 1983, Journal of molecular biology.

Tyrosyl-tRNA synthetase forms a mononucleotide-binding fold.

P. Brick, T. Bhat, D. Blow, 1982, Journal of molecular biology.

A method of positioning a known molecule in an unknown crystal structure

R. A. Crowther, D. M. Blow, D. Blow, 1967 .

The single isomorphous replacement method

Michael G. Rossmann, D. M. Blow, D. Blow, 1961 .

The Mode of Action of Soybean Trypsin Inhibitor as Revealed by Crystal Structure Analysis of the Complex with Porcine Trypsin

J. Janin, D. Blow, R. Sweet, 1974 .

Lipases reach the surface

D. Blow, 1991, Nature.

Design, construction and properties of novel protein molecules - Introduction

D. Blow, 1986 .

The use of x-ray diffraction in the study of protein and nucleic acid structure.

D. Blow, K. Holmes, Kenneth C. Holmes, 1965, Methods of biochemical analysis.

The tortuous story of Asp…His…Ser: Structural analysis of α-chymotrypsin

David M. Blow, D. Blow, 1997 .

So do we understand how enzymes work?

D. Blow, David M. Blow, 2000, Structure.

The arrangement of α-chymotrypsin molecules in the monoclinic crystal form

D. Blow, M. Rossmann, B. A. Jeffery, 1964 .

Parameter refinement in the multiple isomorphous‐replacement method

D. M. Blow, B. Matthews, D. Blow, 1973 .

Site-directed mutagenesis as a probe of enzyme structure and catalysis: tyrosyl-tRNA synthetase cysteine-35 to glycine-35 mutation.

A. Fersht, D. Blow, G. Winter, 1983, Biochemistry.

How Bijvoet made the difference: the growing power of anomalous scattering.

D. Blow, 2003, Methods in enzymology.

The crystal structure of tyrosyl-transfer RNA synthetase at 2-7 A resolution.

M. J. Irwin, D. Blow, J. Nyborg, 1976, Journal of molecular biology.

The peptide chain of tyrosyl tRNA synthetase: no evidence for a super-secondary structure of four alpha-helices.

M. J. Irwin, D. Blow, J. Nyborg, 1977, Biochemical and biophysical research communications.

Structure of a mutant of tyrosyl-tRNA synthetase with enhanced catalytic properties

P. Brick, D. Blow, K. Brown, 1987, Nature.

The study of alpha-chymotrypsin by x-ray diffraction. The Third CIBA Medal Lecture.

D. Blow, D M Blow, 1969, The Biochemical journal.

Direct Methods In Crystallography

David Blow, D. Blow, 1962 .

Molecular mechanics simulations of a conformational rearrangement of D‐xylose in the active site of D‐xylose isomerase

D. Blow, O. Smart, J. Akins, 1992, Proteins.

Atomic CO-ordinates for tosyl-α-chymotrypsin

B. Matthews, D. Blow, J. Birktoft, 1969 .

Structure and Substrate Specificity in the Serine Enzymes

D. Blow, 1974 .

Amino acid activation in crystalline tyrosyl-tRNA synthetase from Bacillus stearothermophilus.

D. Blow, J. Rubin, 1981, Journal of molecular biology.

Binding of tyrosine, adenosine triphosphate and analogues to crystalline tyrosyl transfer RNA synthetase.

D. Blow, C. Monteilhet, 1978, Journal of molecular biology.

Control of nucleation of protein crystals

N E Chayen, D. Blow, N. Chayen, 1994, Protein science : a publication of the Protein Society.

Arthrobacter D-xylose isomerase: protein-engineered subunit interfaces.

D. Blow, B. Hartley, C. Collyer, 1993, The Biochemical journal.

A means of promoting heavy-atom binding in protein crystals.

D. Blow, P. Sigler, 1965, Journal of molecular biology.

CRYSTAL STRUCTURE OF CHOLESTEROL OXIDASE COMPLEXED WITH A STEROID SUBSTRATE. IMPLICATIONS FOR FAD DEPENDENT ALCOHOL OXIDASES

P. Brick, D. Blow, A. Vrielink, 1993 .

A density-modification method for the improvement of poorly resolved protein electron-density maps

T. Bhat, D. Blow, 1982 .

Structure of α-chymotrypsin refined at 1.68 Å resolution☆

D. Blow, H. Tsukada, 1985 .

The refinement of structures partially determined by the isomorphous replacement method

D. Blow, M. Rossmann, 1961 .

Rearrangement of Cruickshank's formulae for the diffraction-component precision index.

D. Blow, D M Blow, 2002, Acta crystallographica. Section D, Biological crystallography.

Conventional X-ray diffraction approaches to the study of enzyme mechanism: serine proteinases, aminoacyl-tRNA synthetases and xylose isomerase

P. Brick, D. Blow, O. Smart, 1992, Philosophical Transactions of the Royal Society of London. Series A: Physical and Engineering Sciences.

The relative positions of independent molecules within the same asymmetric unit

D. Blow, M. Rossmann, E. Coller, 1964 .

The molecular approach to biology

D. Blow, 1962 .

A Method for Refinement of Partially Interpreted Protein Structures Including a Procedure for Scaling Between a Model and an Electron-Density Map

T. Bhat, D. Blow, 1983 .

Mode of action of soybean trypsin inhibitor (Kunitz) as a model for specific protein–protein interactions

J. Janin, D. Blow, R. Sweet, 1974, Nature.

Structural Studies on Molecules of Biological Interest: A volume in honour of Professor Dorothy Hodgkin Edited by Guy Dodson, Jenny P. Glusker and David Sayre Clarendon Press; Oxford, 1981

D. Blow, 1983 .