G. Marshall

发表

G. Marshall, 1987, Annual review of pharmacology and toxicology.

Modeling flexible loops in the dark-adapted and activated states of rhodopsin, a prototypical G-protein-coupled receptor.

G. Marshall, G. Nikiforovich, 2005, Biophysical journal.

Inhibition of Bacterial Virulence: Drug-Like Molecules Targeting the Salmonella enterica PhoP Response Regulator

James J Havranek, Garland R Marshall, Yat T. Tang, 2012, Chemical biology & drug design.

Three-dimensional model for meta-II rhodopsin, an activated G-protein-coupled receptor.

Garland R Marshall, G. Marshall, G. Nikiforovich, 2003, Biochemistry.

Structure of complex of synthetic HIV-1 protease with a substrate-based inhibitor at 2.3 A resolution.

A Wlodawer, G R Marshall, A. Wlodawer, 1989, Science.

THE MOLTEN HELIX : EFFECTS OF SOLVATION ON THE ALPHA - TO 310-HELICAL TRANSITION

G. Marshall, M. Smythe, S. E. Huston, 1995 .

VALIDATE: A New Method for the Receptor-Based Prediction of Binding Affinities of Novel Ligands

Garland R. Marshall, Tudor I. Oprea, Chris L. Waller, 1996 .

3D-QSAR: a current perspective.

G R Marshall, G. Marshall, S. Green, 1995, Trends in pharmacological sciences.

Pro-D-NMe-Amino Acid and D-Pro-NMe-Amino Acid: Simple, Efficient Reverse-Turn Constraints

Garland R. Marshall, David K. Chalmers, G. Marshall, 1995 .

Receptor-based prediction of binding affinities

Garland R. Marshall, Tudor I. Oprea, T. Oprea, 2002 .

Hydroxyethylamine analogues of the p17/p24 substrate cleavage site are tight-binding inhibitors of HIV protease.

G R Marshall, G. Marshall, S. Kent, 1990, Journal of medicinal chemistry.

The early years—Across the bench from Bruce (1963–1966)

G. Marshall, G. Marshall, 2008, Biopolymers.

Analogs of bradykinin with restricted conformational freedom.

G. Marshall, P. Needleman, J. Turk, 1975, Journal of medicinal chemistry.

Chapter 5 Chemogenomics with Protein Secondary-Structure Mimetics

Daniel J. Kuster, G. Marshall, Ye Che, 2015 .

Privileged scaffolds targeting reverse-turn and helix recognition

G. Marshall, Ye Che, 2008, Expert opinion on therapeutic targets.

Factors governing helical preference of peptides containing multiple alpha,alpha-dialkyl amino acids.

G R Marshall, G. Marshall, D. Langs, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Three-dimensional structure of peptide—protein complexes: implications for recognition

Garland R. Marshall, G. Marshall, 1992 .

Free energy profile of a 310- to .alpha.-helical transition of an oligopeptide in various solvents

Garland R. Marshall, Mark L. Smythe, G. Marshall, 1993 .

A hierarchical approach to peptidomimetic design

Garland R. Marshall, G. Marshall, 1993 .

Peptide interactions with G-protein coupled receptors.

G R Marshall, G. Marshall, 2001, Biopolymers.

Peptide‐bond modification for metal coordination: Peptides containing two hydroxamate groups

G. Marshall, Min Liu, Y. Ye, 2003, Biopolymers.

Hydroxamate-based iron chelators: combinatorial syntheses of desferrioxamine B analogues and evaluation of binding affinities.

G. Marshall, U. Słomczyńska, A. Poreddy, 2004, Journal of combinatorial chemistry.

Engineering cyclic tetrapeptides containing chimeric amino acids as preferred reverse-turn scaffolds.

Garland R Marshall, G. Marshall, Ye Che, 2006, Journal of medicinal chemistry.

Novel trihydroxamate‐containing peptides: Design, synthesis, and metal coordination

G. Marshall, Min Liu, Y. Ye, 2006, Biopolymers.

Engineering Metal Complexes of Chiral Pentaazacrowns as Privileged Reverse‐turn Scaffolds

B. Brooks, G. Marshall, D. Riley, 2007, Chemical biology & drug design.

Protein recognition motifs: design of peptidomimetics of helix surfaces.

B. Brooks, G. Marshall, Ye Che, 2007, Biopolymers.

A potential smoothing algorithm accurately predicts transmembrane helix packing

Garland R. Marshall, Jay W. Ponder, Rohit V. Pappu, 1999, Nature Structural Biology.

Targeting the Dimerization of Epidermal Growth Factor Receptors with Small‐Molecule Inhibitors

G. Marshall, L. Pike, Katherine S Yang, 2010, Chemical biology & drug design.

Conformationally restricted TRH analogs: a probe for the pyroglutamate region.

G R Marshall, G. Marshall, M. Gershengorn, 1996, Journal of medicinal chemistry.

Calibration of effective van der Waals atomic contact radii for proteins and peptides

G. Marshall, J. Dunbar, H. Iijima, 1987, Proteins.

Back to the future: Ribonuclease A

Daniel J. Kuster, G. Marshall, J. Feng, 2008, Biopolymers.

Chimeric Protein Engineering

Jianwen A. Feng, G. Marshall, Lee A Tessler, 2007, International Journal of Peptide Research and Therapeutics.

Conformation-function relationships in LHRH analogs. II. Conformations of LHRH peptide agonists and antagonists.

G R Marshall, G. Marshall, G. Nikiforovich, 2009, International journal of peptide and protein research.

5 – Peptide Conformation: Stability and Dynamics

G. Marshall, G. Nikiforovich, D. Beusen, 1995 .

Structural insights of SmKDAC8 inhibitors: Targeting Schistosoma epigenetics through a combined structure-based 3D QSAR, in vitro and synthesis strategy.

G. Marshall, F. Ballante, D. Reddy, 2017, Bioorganic & medicinal chemistry.

Design and Synthesis of Simplified Largazole Analogues as Isoform-Selective Human Lysine Deacetylase Inhibitors.

G. Marshall, F. Ballante, D. N. Reddy, 2016, Journal of medicinal chemistry.

γ-Glutamyl transpeptidase in hydra

G. Marshall, H. Lenhoff, W. Heagy, 1976 .

A crowdsourcing evaluation of the NIH chemical probes.

Tudor I. Oprea, Scott Boyer, Herbert Waldmann, 2009, Nature chemical biology.

Erratum: A crowdsourcing evaluation of the NIH chemical probes

Yvonne C. Martin, Roy J. Vaz, R. Glen, 2009 .

Pharmacology of Antagonists of Angiotensin I and II

G. Marshall, P. Needleman, W. Vine, 1972, Circulation research.

Stimulation of splenic prostaglandin release by angiotensin and specific inhibition by cysteine 8-AII.

G. Marshall, P. Needleman, B. Jaffe, 1973, Prostaglandins.

Specific stimulation and inhibition of renal prostaglandin release by angiotensin analogs.

G. Marshall, P. Needleman, E. Johnson, 1973, The American journal of physiology.

Characterization of central angiotensin II receptors involved in the elicitation of drinking in the rat.

L. Swanson, G. Marshall, P. Needleman, 1973, Brain research.

MODIFICATION OF RESPONSES TO SYMPATHETIC NERVE STIMULATION BY THE RENIN‐ANGIOTENSIN SYSTEM IN RATS

G. Marshall, P. Needleman, E. Johnson, 1974, British journal of pharmacology.

Mechanism and modification of bradykinin-induced coronary vasodilation.

G. Marshall, P. Isakson, P. Needleman, 1975, Proceedings of the National Academy of Sciences of the United States of America.

Is the peripheral sympatho-adrenal nervous system necessary for renal hypertension?

G. Marshall, P. Needleman, E. Johnson, 1976, The Journal of pharmacology and experimental therapeutics.

Differentiation of bradykinin receptors and of kininases with conformational analogues of bradykinin.

G. Marshall, P. Needleman, L. Leduc, 1978, Molecular pharmacology.

Comprehensive model of wild-type and mutant HIV-1 reverse transciptases

Garland R. Marshall, Ira Musmuca, Rino Ragno, 2012, Journal of Computer-Aided Molecular Design.

Cyclopentapeptides as Rigidified Templates for Probing Interactions with the AT-1 Receptors

G. Marshall, A. Hallberg, G. Lindeberg, 2001 .

Drug‐like Leads for Steric Discrimination between Substrate and Inhibitors of Human Acetylcholinesterase

D. Sept, G. Marshall, S. Wildman, 2011, Chemical biology & drug design.

Structural and conformational properties of peptides interacting with the glutathione receptor of hydra.

G. Marshall, M. Cobb, H. Lenhoff, 1982, Molecular pharmacology.

Two purified fractions of alamethicin have different conductance properties

James E. Hall, G. Marshall, I. Vodyanoy, 1982 .

Solid‐phase synthesis: a paradigm shift

G. Marshall, 2003, Journal of peptide science : an official publication of the European Peptide Society.

Helical transitions in peptides containing multiple α,α-dialkyl amino acids

G. Marshall, E. Hodgkin, D. Beusen, 1991 .

Simplified modeling approach suggests structural mechanisms for constitutive activation of the C5a receptor

G. Marshall, G. Nikiforovich, T. Baranski, 2011, Proteins.

SYNTHESIS AND CHARACTERIZATION OF THE MAJOR COMPONENT OF ALAMETHICIN

T. M. Balasubramanian, James E. Hall, G. Marshall, 1982 .

Development and Maintenance of Renal Hypertension in Normal and Guanethidine Sympathectomized Rats

B. K. Hartman, G. Marshall, Eugene M. Johnson, 1975, Circulation research.

Blood vessel-hormone interactions: angiotensin, bradykinin, and prostaglandins.

G. Marshall, P. Needleman, S. Denny, 1977, The American journal of physiology.

Determinants and modification of adrenergic and vascular resistance in the kidney.

G. Marshall, P. Needleman, E. Johnson, 1974, The American journal of physiology.

EPR Studies of Functionally Active, Nitroxide Spin-Labeled Peptide Analogs of the C-terminus of a G-Protein Alpha Subunit

G. Marshall, T. Baranski, N. V. Eps, 2010 .

Tauroursodeoxycholic acid binds to the G‐protein site on light activated rhodopsin

Christina M. Taylor, G. Marshall, C. Taylor, 2018, Experimental eye research.

HIV-1 protease inhibitors: ketomethylene isosteres with unusually high affinity compared with hydroxyethylene isostere analogs.

G. Marshall, R. Mueller, M. Toth, 1994, Bioorganic & medicinal chemistry.

Solid-Phase Peptide Synthesis: Historical Aspects

G. Marshall, 2011 .

Bound conformations for ligands for G-protein coupled receptors

G. Marshall, R. Ragno, R. Arimoto, 1999, Letters in Peptide Science.

Structure of Alamethicin in solution. One- and two-dimensional 1H nuclear magnetic resonance studies at 500 MHz.

G. Marshall, S. Chan, U. Banerjee, 1983, Journal of molecular biology.

A specific competitive inhibitor of angiotensin II.

G. Marshall, W. Vine, P. Needlemann, 1970, Proceedings of the National Academy of Sciences of the United States of America.

Profile of circulating vasoactive substances in hemorrhagic shock and their pharmacologic manipulation.

Janet L. Kourik, G. Marshall, P. Needleman, 1974, The Journal of clinical investigation.

Deducing 3D Models of the Activated States for TM Regions of GPCRs by Modeling Constitutively Active Mutants: The Test Case of Opsin

G. Marshall, G. Nikiforovich, 2006 .

Conformational templates for rational drug design: flexibility of cyclo(D-Pro1-Ala2-Ala3-Ala4-Ala5) in DMSO solution.

Xuan Zhang, G. Marshall, G. Nikiforovich, 2007, Journal of medicinal chemistry.

Molecular Modeling Suggests Conformational Scaffolds Specifically Targeting Five Subtypes of Somatostatin Receptors

S. Achilefu, G. Marshall, G. Nikiforovich, 2007, Chemical biology & drug design.

Renal concentrations of prostaglandin E in acute and chronic renal ischemia.

G. Marshall, P. Needleman, B. Jaffe, 1972, Biochemical and biophysical research communications.

Relative Strength of Cation-π vs Salt-Bridge Interactions: The Gtα(340−350) Peptide/Rhodopsin System

G. Marshall, D. Cistola, W. Sha, 2006 .

Tracheal cytotoxin structural requirements for respiratory epithelial damage in pertussis

G. Marshall, W. Goldman, A. Tyler, 1995, Molecular microbiology.

Work in progress: Angiotensin III - induced prostaglandin (PG) release

G. Marshall, E. Puré, P. Needleman, 1976 .

Prostaglandin release from vasculature by angiotensin II: dissociation from lipolysis.

G. Marshall, P. Needleman, J. R. Douglas, 1973, European journal of pharmacology.

Receptor-Bound Conformation of α-Peptide of Transducin (Gt) is not Stabilized by a “π-Cation” Interaction but by Constrained Lactam Bridges Between Residues 341 and 350

G. Marshall, W. Sha, R. Arimoto, 2001 .

Synthetic approaches to peptide analogues containing 4, 4-difluoro-L-proline and 4-keto-L-proline.

G. Marshall, J. Sufrin, T. Balasubramanian, 2009, International journal of peptide and protein research.

3D-QSAR of angiotensin-converting enzyme and thermolysin inhibitors: A comparison of CoMFA models based on deduced and experimentally determined active site geometries

Garland R. Marshall, G. Marshall, C. B. Naylor, 1993 .

Constrained Peptidomimetics for TRH: cis-Peptide Bond Analogs

Garland R. Marshall, Marvin C. Gershengorn, Kevin D. Moeller, 2000 .

Peptides: Chemistry, Structure and Biology

Garland R. Marshall, G. Marshall, J. Rivier, 1990 .

Stereoselective synthesis of optically active beta-lactams, potential inhibitors of pilus assembly in pathogenic bacteria.

G. Marshall, S. Hultgren, F. Almqvist, 2000, Organic letters.

Antimycobacterial pyrroles: synthesis, anti-Mycobacterium tuberculosis activity and QSAR studies.

G. Marshall, M. Artico, R. Di Santo, 2000, Bioorganic & medicinal chemistry.

CHAPTER 3 – Solid Phase Synthesis: The Use of Solid Supports and Insoluble Reagents in Peptide Synthesis

G. Marshall, R. B. Merrifield, 1971 .

Effect of hydroxyl group configuration in hydroxyethylamine dipeptide isosteres on HIV protease inhibition. Evidence for multiple binding modes.

G. Marshall, R. Mueller, D. Rich, 1991, Journal of medicinal chemistry.

Design, synthesis, and metal binding of novel Pseudo- oligopeptides containing two phosphinic acid groups.

G. Marshall, Min Liu, Y. Ye, 2008, Biopolymers.

Analysis of the interaction of haloenol lactone suicide substrates with .alpha.-chymotrypsin using computer graphics and molecular mechanics

G. Marshall, J. Katzenellenbogen, S. Daniels, 1985 .

Polymeric coordination compounds. The synthesis and applications of selective ionexchangers and polymeric chelate compounds.

G. Nickless, G. Marshall, 1964, Chromatographic reviews.

Derivation of a three-dimensional pharmacophore model of substance P antagonists bound to the neurokinin-1 receptor.

G R Marshall, G. Marshall, D. Beusen, 1998, Journal of medicinal chemistry.

.alpha.-Helical versus 310-Helical Conformation of Alanine-Based Peptides in Aqueous Solution: An Electron Spin Resonance Investigation

G. Marshall, C. Nakaie, M. Smythe, 1995 .

Conformational mimicry. 3. Synthesis and incorporation of 1,5-disubstituted tetrazole dipeptide analogs into peptides with preservation of chiral integrity: bradykinin

Garland R. Marshall, James B. Dunbar, G. Marshall, 1992 .

Conformational mimicry. 1. 1,5-Disubstituted tetrazole ring as a surrogate for the cis amide bond

Garland R. Marshall, James B. Dunbar, Hiroshi Iijima, 1988 .

Conformational mimicry: Synthesis and solution conformation of a cyclic somatostatin hexapeptide containing a tetrazole cis amide bond surrogate

G. Marshall, R. Head, J. Zabrocki, 1995, Biopolymers.

The 1,5-Disubstituted Tetrazole Ring as a cis-Amide Bond Surrogate.

G. Marshall, J. Zabrocki, 1999, Methods in molecular medicine.

Conformational mimicry. II. An obligatory cis amide bond in a small linear peptide.

G R Marshall, G. Marshall, G. D. Smith, 2009, International journal of peptide and protein research.

Peptide Bond Modification for Metal Coordination: 3. Metal-Binding Properties of Phosphorus-Based Pseudo-peptides

G. Marshall, Y. Ye, 2001 .

Stereoselective syntheses of 3-mercaptoproline derivatives protected for solid phase peptide synthesis.

G R Marshall, G. Marshall, S A Kolodziej, 2009, International journal of peptide and protein research.

Electrochemical Cyclization of Dipeptides To Form Novel Bicyclic, Reverse-Turn Peptidomimetics. 2. Synthesis and Conformational Analysis of 6,5-Bicyclic Systems

G. Marshall, D. Chalmers, M. Smythe, 1996 .

Anodic amide oxidations: Conformationally restricted peptide building blocks from the direct oxidation of dipeptides

G. Marshall, Y. M. Fobian, U. Słomczyńska, 1994 .

Studies with alpha-methyl amino acids. Resolution and amino protection.

G. Marshall, J. Turk, G. T. Panse, 1975, The Journal of organic chemistry.

Helix stability of oligoglycine, oligoalanine, and oligo‐β‐alanine dodecamers reflected by hydrogen‐bond persistence

Jay W Ponder, Garland R Marshall, J. Ponder, 2014, Proteins.

Synthesis of the phenylpyridal scaffold as a helical peptide mimetic.

Daniel J. Kuster, G. Marshall, G. Bourne, 2010, Chemistry.

Chapter 24. Peptide Conformation and Biological Activity

G. Marshall, F. Gorin, M. Moore, 1978 .

Evaluation of two new coupling agents for incorporation of α,α-dialkylamino acids, such as α-methylalanine, in solid-phase peptide synthesis

G. Marshall, U. Słomczyńska, Alan C. Sapia, 1995, Letters in Peptide Science.

Emerimicins III and IV and Their Ethylalanine12 Epimers. Facilitated Chemical-Enzymatic Synthesis and a Qualitative Evaluation of Their Solution Structures

W. Hutton, G. Marshall, J. Zabrocki, 1992 .

A facile synthesis of 3-substituted pipecolic acids, chimeric amino acids

Garland R. Marshall, Gergely M. Makara, G. Marshall, 1997 .

Solvation of the polymer matrix. Source of truncated and failure sequences in solid phase synthesis

G. Marshall, W. Hancock, P. Vagelos, 1973 .

Synthesis of Angiotensins by the Solid-Phase Method*

G. Marshall, R. B. Merrifield, 1965 .

Conformational analysis and helical preferences of normal and α,α‐dialkyl amino acids

Garland R. Marshall, Edward E. Hodgkin, G. Marshall, 1990 .

4.02 – Introduction to Computer-Assisted Drug Design – Overview and Perspective for the Future

C. M. Taylor, G. R. Marshall, G. Marshall, 2007 .

Solvent exposure of specific nuclei of angiotensin II determined by NMR solvent saturation method

G. Marshall, J. Dadok, J. Glickson, 1974, Nature.

Proton magnetic double-resonance study of angiotensin II (Asn1Val5) in aqueous solution employing correlation spectroscopy. Assignment of peptide NH resonances and transfer of saturation from water.

G. Marshall, J. Dadok, J. Glickson, 1974, Biochemistry.

NMR Evidence against γ Turn and β Turn Models of Angiotensin II in Aqueous Solution

G. Marshall, J. Glickson, W. Vine, 1973 .

Hormone Interactions in the Isolated Rabbit Heart: SYNTHESIS AND CORONARY VASOMOTOR EFFECTS OF PROSTAGLANDINS, ANGIOTENSIN, AND BRADYKININ

G. Marshall, B. Sobel, P. Needleman, 1975, Circulation research.

Design, synthesis, and biological evaluation of stable β6.3-Helices: Discovery of non-hemolytic antibacterial peptides.

G. Marshall, P. Schlesinger, Sukrit Singh, 2018, European journal of medicinal chemistry.

Conformational Analysis of Reverse-Turn Constraints by N-Methylation and N-Hydroxylation of Amide Bonds in Peptides and Non-Peptide Mimetics

Garland R. Marshall, Yasuo Takeuchi, G. Marshall, 1998 .

Alamethicin. A rich model for channel behavior.

T. M. Balasubramanian, G R Marshall, G. Marshall, 1984, Biophysical journal.

The Conformational Parameter in Drug Design: The Active Analog Approach

Garland R. Marshall, C. D. Barry, Richard A. Dammkoehler, 1979 .

Determination of an 8-Å interatomic distance in a helical peptide by solid-state NMR spectroscopy

R. A. Mckay, G. Marshall, S. Vega, 1992 .

Pyrolysis-mass spectrometry of polymers—II. Polyurethanes

G. Marshall, 1983 .

EFFICIENT ONE-POT SYNTHESIS OF JM3100

G. Marshall, D. Guillaume, 1998 .

Investigation and parametrization of a molecular dielectric function

C. D. Barry, G. Marshall, D. A. Greenberg, 1978 .

Modulating G-protein coupled receptor/G-protein signal transduction by small molecules suggested by virtual screening.

Garland R Marshall, Christina M. Taylor, Yaniv Barda, 2008, Journal of medicinal chemistry.

Targeting Lysine Deacetylases (KDACs) in Parasites

Garland R. Marshall, Bruce A. Rosa, Makedonka Mitreva, 2015, PLoS neglected tropical diseases.

Therapeutic approaches to human immunodeficiency virus: structural studies on G-protein-coupled receptors.

G. Marshall, 1997, Pharmacology & therapeutics.

Validated ligand mapping of ACE active site

Garland R. Marshall, Daniel J. Kuster, G. Marshall, 2005, J. Comput. Aided Mol. Des..

Partial sequence of rat prothrombin and the activity of two related pentapeptides as substrates for the vitamin K‐dependent carboxylase system

G. Marshall, D. Carey, R. Olson, 1977, FEBS letters.

Acyl carrier protein. 28. Chemical synthesis and characterization of a protein with acyl carrier protein activity.

G. Marshall, W. Hancock, P. Vagelos, 1972, The Journal of biological chemistry.

Development of small molecules designed to modulate protein–protein interactions

Garland R. Marshall, Bernard R. Brooks, Ye Che, 2006, J. Comput. Aided Mol. Des..

G-protein alpha and beta–gamma subunits interact with conformationally distinct signaling states of rhodopsin

G. Marshall, M. A. Downs, R. Arimoto, 2006, Vision Research.

Rhodopsin-transducin interface: studies with conformationally constrained peptides.

G. Marshall, R. Arimoto, G. Makara, 2001, Biophysical journal.

Conformationally readdressed CCK‐B/δ‐opioid pepitide ligands

G R Marshall, G. Marshall, G. Nikiforovich, 1995, Biopolymers.

Bradykinin and angiotensin II analogs containing a conformationally constrained proline analog.

G R Marshall, G. Marshall, C. Humblet, 2009, International journal of peptide and protein research.

Preparation and use of benzhydrylamine polymers in peptide synthesis. II. Syntheses of thyrotropin releasing hormone, thyrocalcitonin 26-32, and eledoisin.

G. Marshall, P. Pietta, K. Takahashi, 1974, The Journal of organic chemistry.

Design, synthesis and QSAR studies on N-aryl heteroarylisopropanolamines, a new class of non-peptidic HIV-1 protease inhibitors.

G. Marshall, M. Artico, R. Di Santo, 2002, Bioorganic & medicinal chemistry.

Design and synthesis of benzodiazepine analogs as isoform-selective human lysine deacetylase inhibitors.

G. Marshall, F. Ballante, D. Reddy, 2017, European journal of medicinal chemistry.

Identification of histone deacetylase inhibitors with (arylidene)aminoxy scaffold active in uveal melanoma cell lines

G. Marshall, F. Ballante, S. Nencetti, 2020, Journal of enzyme inhibition and medicinal chemistry.

Synthesis, biological activity, and 19 F nuclear magnetic resonance spectra of angiotensin II analogs containing fluorine.

G. Marshall, P. Needleman, W. Vine, 1973, Biochemistry.

Effects of electric field on alamethicin bound at the lipid-water interface: a molecular mechanics study.

G. Marshall, S. Galaktionov, 1993, Biophysical journal.

An Automated Strategy for Binding-Pose Selection and Docking Assessment in Structure-Based Drug Design

Garland R. Marshall, Flavio Ballante, G. Marshall, 2016, J. Chem. Inf. Model..

Identification of the T-cell and Ia contact residues of a T-cell antigenic epitope

E. Unanue, G. Marshall, P. Allen, 1987, Nature.

Combinations of isoform-targeted histone deacetylase inhibitors and bryostatin analogues display remarkable potency to activate latent HIV without global T-cell activation

G. Marshall, Robert M. Williams, L. Ratner, 2017, Scientific Reports.

The biology and future prospects of antivirulence therapies

G. Marshall, S. Hultgren, L. Cegelski, 2008, Nature Reviews Microbiology.

Peptides Structure and Biology

G. Marshall, J. Rivier, 1990 .

Electrochemical Cyclization of Dipeptides toward Novel Bicyclic, Reverse-Turn Peptidomimetics. 1. Synthesis and Conformational Analysis of 7,5-Bicyclic Systems

Garland R. Marshall, Mark L. Smythe, Kevin D. Moeller, 1995 .

High-Resolution Crystal Structures of Protein Helices Reconciled with Three-Centered Hydrogen Bonds and Multipole Electrostatics

Daniel J. Kuster, J. Ponder, G. Marshall, 2015, PloS one.

Conformational effects of chiral α,α‐dialkyl amino acids I. C‐Terminal tetrapeptides of emerimicin containing α‐ethylalanine

G. Marshall, J. Dunbar, G. D. Smith, 2009 .

Alkylating angiotensin II analogues: synthesis, analysis, and biological activity of angiotensin II analogues containing the nitrogen mustard melphalan in position 8.

G. Marshall, K. Hsieh, 1981, Journal of medicinal chemistry.

ProVal: A protein‐scoring function for the selection of native and near‐native folds

Eric A Welsh, Garland R Marshall, Richard D Head, 2003, Proteins.

alpha-Methyl substrates of carboxypeptidase A. A steric probe of the active site.

G R Marshall, G. Marshall, J. Turk, 1975, Biochemistry.

Ab initio modeling of small, medium, and large loops in proteins.

G R Marshall, G. Marshall, G. Nikiforovich, 2001, Biopolymers.

Histone Deacetylase Inhibitors: Structure-Based Modeling and Isoform-Selectivity Prediction

Garland R. Marshall, Rino Ragno, Flavio Ballante, 2012, J. Chem. Inf. Model..

Computational Approaches in Peptide and Protein Design: An Overview

G. Marshall, G. Nikiforovich, 2009 .

A simple, continuous fluorometric assay for HIV protease.

G. Marshall, M. Toth, Garland R. Marshall, 2009, International journal of peptide and protein research.

Introduction to Chemoinformatics in Drug Discovery – A Personal View

Garland R. Marshall, G. Marshall, 2005 .

A second dimension in complexity in combinatorial peptide libraries

G. Marshall, G. Hortin, R. Panek, 1994 .

Insight into the Binding Mode for Cyclopentapeptide Antagonists of the CXCR4 Receptor

Garland R Marshall, G. Marshall, G. Nikiforovich, 2006, Chemical biology & drug design.

A minimalistic 3D pharmacophore model for cyclopentapeptide CXCR4 antagonists

G. Marshall, G. Nikiforovich, J. Våbenø, 2006, Biopolymers.

Virtual screening for lead discovery.

Yat T Tang, Garland R Marshall, Yat T. Tang, 2011, Methods in molecular biology.

Ac-[3- and 4-alkylthioproline31]-CCK4 analogs: synthesis and implications for the CCK-B receptor-bound conformation.

G R Marshall, G. Marshall, G. Nikiforovich, 1995, Journal of medicinal chemistry.

Do benzodiazepines mimic reverse-turn structures?

Garland R. Marshall, Masayuki Hata, G. Marshall, 2006, J. Comput. Aided Mol. Des..

The synthesis and characterization of the amino-terminal octapeptide of mouse nerve growth factor.

G. Marshall, R. Bradshaw, R. Hogue-Angeletti, 2009, International journal of peptide and protein research.

Evolving macromodular molecular modeling system.

C. D. Barry, R. A. Ellis, H E Bosshard, 1974, Federation proceedings.

Crystal structures and conformational calculations of fragments of alamethicin containing aminoisobutyric acid

T. M. Balasubramanian, E. W. Czerwinski, G. Marshall, 1981 .

Factors governing helical preference of peptides containing multiple a,a-dialkyl amino acids

G. Marshall, J. Zabrocki, M. Leplawy, 2022 .

Defining the interface between the C-terminal fragment of alpha-transducin and photoactivated rhodopsin.

Christina M. Taylor, G. Marshall, G. Nikiforovich, 2007, Biophysical journal.

Modeling of the complex between transducin and photoactivated rhodopsin, a prototypical G-protein-coupled receptor.

Christina M. Taylor, G. Marshall, G. Nikiforovich, 2007, Biochemistry.

Motion of Carboxyl Terminus of Gα Is Restricted upon G Protein Activation

G. Marshall, T. Baranski, Steven O. Smith, 2005, Journal of Biological Chemistry.

Light-activated rhodopsin induces structural binding motif in G protein alpha subunit.

G R Marshall, J. Ponder, G. Marshall, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Effect of glutathione on cyclic nucleotide levels in hydra attenuata

G. Marshall, M. Cobb, H. Lenhoff, 1980 .

Solid-phase synthesis of methyl carboxymycobactin T 7 and analogues as potential antimycobacterial agents.

G. Marshall, C. Ratledge, U. Słomczyńska, 2003, Bioorganic & medicinal chemistry letters.

Determination of a precise interatomic distance in a helical peptide by REDOR NMR

G. Marshall, J. Schaefer, M. Leplawy, 1990 .

Bordetella pertussis tracheal cytotoxin and other muramyl peptides: distinct structure-activity relationships for respiratory epithelial cytopathology.

G. Marshall, W. Goldman, K. Luker, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Molecular recognition using motion of molecules under Coulomb's Law

G. Klimov, G. Marshall, 1994 .

A unique geometry of the active site of angiotensin-converting enzyme consistent with structure-activity studies

Dorica Mayer, Christopher B. Naylor, Ioan Motoc, 1987, J. Comput. Aided Mol. Des..

The development and application of a novel safety-catch linker for BOC-based assembly of libraries of cyclic peptides.

G. Marshall, W. Meutermans, M. Smythe, 2001, The Journal of organic chemistry.

Three-dimensional QSAR of human immunodeficiency virus (I) protease inhibitors. 1. A CoMFA study employing experimentally-determined alignment rules.

Tudor I. Oprea, T I Oprea, G R Marshall, 1993, Journal of medicinal chemistry.

Modeling molecular mechanisms of binding of the anaphylatoxin C5a to the C5a receptor.

G. Marshall, G. Nikiforovich, T. Baranski, 2008, Biochemistry.

α/310‐Helix transitions in α‐methylalanine homopeptides: Conformational transition pathway and potential of mean force

Garland R. Marshall, G. Marshall, S. E. Huston, 1994 .

CYANOGEN BROMIDE AS A CLEAVAGE PROCEDURE IN SOLID PHASE PEPTIDE SYNTHESIS

G. Marshall, W. Hancock, 1976 .

Letter: Cyanogen bromide as a cleavage procedure in solid phase peptide synthesis.

G. Marshall, W. Hancock, 1975, Journal of the American Chemical Society.

Role of the C-terminal carboxylate in angiotensin II activity: alcohol, ketone, and ester analogues of angiotensin II.

G. Marshall, K. Hsieh, 1986, Journal of medicinal chemistry.

Inhibitors of HIV protease based on modified peptide substrates

G. Marshall, S. Kent, L. Ratner, 1990 .

Interaction of glutathione analogues with Hydra attenuata γ-glutamyltransferase

G. Marshall, M. Cobb, H. Lenhoff, 1978 .

Limiting assumptions in structure-based design: binding entropy

Garland R. Marshall, G. Marshall, 2012, Journal of Computer-Aided Molecular Design.

Conformation-function relationships in LHRH analogs. I. Conformations of LHRH peptide backbone.

G R Marshall, G. Marshall, G. Nikiforovich, 2009, International journal of peptide & protein research.

Studies with Tryptophan in Solid-Phase Synthesis

G. Marshall, 1968 .

Long-acting angiotensin II inhibitors containing hexafluorovaline in position 8.

G. Marshall, P. Needleman, K. Hsieh, 1987, Journal of medicinal chemistry.

Limiting assumptions in molecular modeling: electrostatics

Garland R. Marshall, G. Marshall, 2013, Journal of Computer-Aided Molecular Design.

Relative strength of cation-pi vs salt-bridge interactions: the Gtalpha(340-350) peptide/rhodopsin system.

G. Marshall, D. Cistola, W. Sha, 2006, Journal of the American Chemical Society.

Computer-aided molecular modeling of a D2-agonist dopamine pharmacophore

Garland R. Marshall, James Dunbar, Roberto Tonani, 1987, J. Comput. Aided Mol. Des..

Angiotensin II. Synthesis and biological activity of 8-(R and S)-tetrahydroisoquinoline and 7-(R and S)-(proline)thiazole analogs

G. Marshall, P. Balasubramanian, 1988 .

Amide protection and amide supports in solid-phase peptide synthesis

G. Marshall, P. Pietta, 1970 .

From Merrifield to MetaPhore: A Random Walk with Serendipity

G. Marshall, 2001 .

Synthesis of cyclic peptides on dual function supports.

G. Marshall, E. Flanigan, 1970, Tetrahedron letters.

Peptide modeling—An overview

G. Marshall, G. Nikiforovich, D. Beusen, 1994 .

Systematic search in conformational analysis

Garland R. Marshall, E. F. Berkley Shands, Richard A. Dammkoehler, 1996 .

Molecular Shape Descriptors. 1. Three-Dimensional Molecular Shape Descriptor

G. Marshall, I. Motoc, R. Dammkoehler, 1985 .

Conformational analysis of two cyclic analogs of angiotensin: implications for the biologically active conformation.

G. Marshall, G. Nikiforovich, J. Kao, 1994, Biochemistry.

Electron paramagnetic resonance studies of functionally active, nitroxide spin-labeled peptide analogues of the C-terminus of a G-protein alpha subunit.

G. Marshall, W. Hubbell, T. Baranski, 2010, Biochemistry.

Angiotensin (A I, A II, A III) receptor characterization. Correlation of prostaglandin release with peptide degradation.

G. Marshall, P. Needleman, S. Denny, 1977, Circulation research.

Structure‐Activity Studies: A Three‐Dimensional Probe of Receptor Specificity

G. Marshall, 1985 .

Three‐dimensional computer modeling as an aid to drug design

Garland R. Marshall, Christine Humblet, G. Marshall, 1981 .

Alternate Binding Mode of C‐terminal Phenethylamine Analogs of Gtα(340–350) to Photoactivated Rhodopsin

G. Marshall, D. Cistola, O. Kisselev, 2006 .

Structure of rhodopsin-bound C-terminal α-peptide of transducin

G. Marshall, N. Gautam, Y. Fann, 2002 .

Metal complexes of chiral pentaazacrowns as conformational templates for β-turn recognition

Chris M. W. Ho, Garland R. Marshall, Andrea J. H. Reaka, 2002, J. Comput. Aided Mol. Des..

Impact of azaproline on Peptide conformation.

Garland R Marshall, G. Marshall, Ye Che, 2004, The Journal of organic chemistry.

Impact of Cis‐proline analogs on peptide conformation

Garland R Marshall, G. Marshall, Ye Che, 2006, Biopolymers.

Conformationally restricted TRH analogues: constraining the pyroglutamate region.

G. Marshall, C. Ho, M. Gershengorn, 2002, Bioorganic & medicinal chemistry.

Three-dimensional quantitative structure-activity relationship of human immunodeficiency virus (I) protease inhibitors. 2. Predictive power using limited exploration of alternate binding modes.

Tudor I. Oprea, T I Oprea, G R Marshall, 1994, Journal of medicinal chemistry.

Chapter 28. Pharmacophore Identification and Receptor Mapping

Garland R. Marshall, Christine Humblet, G. Marshall, 1980 .

Molecular Shape Descriptors. 3. Steric Mapping of Biological Receptor

G. Marshall, I. Motoc, J. Labanowski, 1985 .

Computer-assisted analysis of bioactivity. I. - Active conformation of histamine H1 receptor antagonists

G. Marshall, I. Motoc, S. Naruto, 1985 .

Molecular dynamics of β-hairpin models of epigenetic recognition motifs.

J. Ponder, G. Marshall, Chuanjie Wu, 2012, Journal of the American Chemical Society.

Proposal for the biologically active conformation of opiates and enkephalin.

G R Marshall, G. Marshall, F. Gorin, 1977, Proceedings of the National Academy of Sciences of the United States of America.

3D model for TM region of the AT-1 receptor in complex with angiotensin II independently validated by site-directed mutagenesis data.

G R Marshall, G. Marshall, G. Nikiforovich, 2001, Biochemical and biophysical research communications.

Novel approach to computer modeling of seven-helical transmembrane proteins: current progress in the test case of bacteriorhodopsin.

G R Marshall, G. Marshall, G. Nikiforovich, 2001, Acta biochimica Polonica.

Using Ligand‐Based Virtual Screening to Allosterically Stabilize the Activated State of a GPCR

Garland R Marshall, Christina M. Taylor, Anna-Karin Tunemalm, 2010, Chemical biology & drug design.

Novel analogues of enkephalin: indentification of functional groups required for biological activity.

G. Marshall, F. Gorin, T. Cicero, 1980, Journal of medicinal chemistry.

Novel cyclic analogs of angiotensin II with cyclization between positions 5 and 7: conformational and biological implications.

G. Marshall, G. Nikiforovich, E. Escher, 1996, Journal of medicinal chemistry.

The utility of side‐chain cyclization in determining the receptor‐bound conformation of peptides: Cyclic tripeptides and angiotensin II

G. Marshall, D. Beusen, John D. Clark, 1992, Biopolymers.

Conformational manifold of α-aminoisobutyric acid (Aib) containing alanine-Based tripeptides in aqueous solution explored by vibrational spectroscopy, electronic circular dichroism spectroscopy, and molecular dynamics simulations

Garland R. Marshall, Jianwen A. Feng, Gregory T. Bourne, 2007 .

Structures from NMR distance constraints.

G R Marshall, G. Marshall, H. Iijima, 1990, Biochemical pharmacology.

THE GENERATION OF THREE-DIMENSIONAL STRUCfURES FROM NMR-DERIVED CONSTRAINTS

Garland R. Marshall, G. Marshall, D. Beusen, 1989 .

tert-Butoxycarbonyl-α-methyl-l-phenylalanyl-l-valine benzyl ester

T. M. Balasubramanian, G. Marshall, P. Roey, 1981 .

Angiotensin II: STUDIES ON THE BIOLOGICALLY ACTIVE CONFORMATION

G. Marshall, H. Bosshard, 1972, Circulation research.

Impact of azaproline on amide cis-trans isomerism: conformational analyses and NMR studies of model peptides including TRH analogues.

Garland R Marshall, G. Marshall, A. Berglund, 2003, Journal of the American Chemical Society.

Elucidation of the receptor-bound conformation of the enkephalins.

T. M. Balasubramanian, C. D. Barry, G. Marshall, 1978, Journal of supramolecular structure.

A virtual library of constrained cyclic tetrapeptides that mimics all four side-chain orientations for over half the reverse turns in the protein data bank

Garland R. Marshall, Sage Arbor, G. Marshall, 2009, J. Comput. Aided Mol. Des..

c[D‐pro‐Pro‐D‐pro‐N‐methyl‐Ala] adopts a rigid conformation that serves as a scaffold to mimic reverse‐turns

Sage Arbor, Garland R Marshall, G. Marshall, 2008, Biopolymers.

Esterase mutation is a mechanism of resistance to antimalarial compounds

Victoria C. Corey, E. Winzeler, G. Marshall, 2017, Nature Communications.

A second look at mini-protein stability: analysis of FSD-1 using circular dichroism, differential scanning calorimetry, and simulations.

Jianwen A. Feng, G. Marshall, J. Kao, 2009, Biophysical journal.

SKATE: A docking program that decouples systematic sampling from scoring

Garland R. Marshall, Jianwen A. Feng, G. Marshall, 2010, J. Comput. Chem..

Modeling the possible conformations of the extracellular loops in G‐protein‐coupled receptors

Garland R Marshall, Christina M. Taylor, G. Marshall, 2010, Proteins.

Combinatorial Chemistry of Metal-Binding Ligands CHAPTER 5 COMBINATORIAL CHEMISTRY OF METAL-BINDING LIGANDS

G. Marshall, G. Gokel, U. Słomczyńska, 2002 .

PHOENIX: A Scoring Function for Affinity Prediction Derived Using High-Resolution Crystal Structures and Calorimetry Measurements

Garland R. Marshall, Yat T. Tang, G. Marshall, 2011, J. Chem. Inf. Model..

Protein-Protein Docking Methods

Garland R. Marshall, Ilya A. Vakser, I. Vakser, 2005 .

Evidence for multiple binding modes to the μ-opioid receptor

G. Marshall, D. Oliver, 1991 .

Constrained search of conformational hyperspace

Garland R. Marshall, E. F. Berkley Shands, Richard A. Dammkoehler, 1989, J. Comput. Aided Mol. Des..

FOUNDATION: A program to retrieve all possible structures containing a user-defined minimum number of matching query elements from three-dimensional databases

Chris M. W. Ho, Garland R. Marshall, G. Marshall, 1993, J. Comput. Aided Mol. Des..

Molecular mechanisms of constitutive activity: mutations at position 111 of the angiotensin AT1 receptor.

G. Marshall, G. Nikiforovich, K. Catt, 2005, The journal of peptide research : official journal of the American Peptide Society.

Three-dimensional recognition requirements for angiotensin agonists: a novel solution for an old problem.

G R Marshall, G. Marshall, G. Nikiforovich, 1993, Biochemical and biophysical research communications.

Virtual screening for lead discovery.

Yat T. Tang, G. Marshall, 2011, Methods in molecular biology.

SYNTHESIS OF FLUORINE-CONTAINING PEPTIDES. ANALOGS OF ANGIOTENSIN II CONTAINING HEXAFLUOROVALINE

G. Marshall, W. Vine, K. Hsieh, 1982 .

Identification of isoform-selective hydroxamic acid derivatives that potently reactivate HIV from latency

G. Marshall, Elleard Heffern, G. Kyei, 2019, Journal of virus eradication.

SPLICE: A program to assemble partial query solutions from three-dimensional database searches into novel ligands

Chris M. W. Ho, Garland R. Marshall, G. Marshall, 1993, J. Comput. Aided Mol. Des..

Cavity search: An algorithm for the isolation and display of cavity-like binding regions

Chris M. W. Ho, Garland R. Marshall, G. Marshall, 1990, J. Comput. Aided Mol. Des..

13C and 1H resonance assignments and structural determination of an emerimicin peptide in DMSO

W. Hutton, G. Marshall, J. Zabrocki, 1991 .

The solution NMR structure of emerimicins III and IV determined using the new program, MACROSEARCH

W. Hutton, G. Marshall, R. Head, 1993 .

Conformational Model of Signal Transduction in the Transmembrane Region of the AT-1 Receptor

G. Marshall, G. Nikiforovich, 2001 .

Synthesis of gramicidin analogs with conformationally constrained dipeptides

G. Marshall, J. Kao, Wei-jun Zhang, 2002 .

Sampling conformational hyperspace: Techniques for improving completeness

Garland R. Marshall, E. F. Berkley Shands, Richard A. Dammkoehler, 1995, J. Comput. Aided Mol. Des..

C-terminally shortened alamethicin on templates: influence of the linkers on conductances.

G. Marshall, M. Leplawy, H. Duclohier, 1999, Biochimica et biophysica acta.

3D modeling of the activated states of constitutively active mutants of rhodopsin.

G. Marshall, G. Nikiforovich, 2006, Biochemical and biophysical research communications.

3 D modeling of the activated states of constitutively active mutants of rhodopsin q

G. Marshall, G. Nikiforovich, 2010 .

AZASERINE AFFINITY LABELLING OF 7-GLUTAMYL TRANSFERASE OF HYDRA ATTENUATA WITHOUT INACTIVATION OF THE GLUTATHIONE RECEPTOR

G. Marshall, M. Cobb, H. Lenhoff, 1982 .

Kinetics of Interactions between Drugs and Receptors: Stochastic Conception

G. Klimov, G. Marshall, 1993 .

Efficient regioselective synthesis of enantiomerically pure 4-hydroxymethyl-Δ2-thiazoline

G. Marshall, S. Hultgren, F. Almqvist, 1998 .

Interactions between Conserved Residues in Transmembrane Helices 2 and 7 during Angiotensin AT1 Receptor Activation

G. Marshall, L. Hunyady, G. Nikiforovich, 2006, Chemical biology & drug design.

Three‐Dimensional QSAR of Human Immunodeficiency Virus (I) Protease Inhibitors. Part 1. A CoMFA Study Employing Experimentally‐Determined Alignment Rules.

Tudor I. Oprea, G. Marshall, C. Waller, 1994 .

ANALYSIS OF THE INTERACTION OF HALOENOL LACTONE SUICIDE SUBSTRATES WITH α-CHYMOTRYPSIN USING COMPUTER GRAPHICS AND MOLECULAR MECHANICS

G. Marshall, J. Katzenellenbogen, S. Daniels, 1985 .

Van der Waals volume fragmental constants

Garland R. Marshall, Ioan Motoc, G. Marshall, 1985 .