J. Boehm

发表

N-Phenyl-N-purin-6-yl ureas: the design and synthesis of p38alpha MAP kinase inhibitors.

Zehong Wan, J. Boehm, M. Bower, 2003, Bioorganic & medicinal chemistry letters.

Structural basis of inhibitor selectivity in MAP kinases.

E. Goldsmith, J. Boehm, J. Adams, 1998, Structure.

Regulation of stress-induced cytokine production by pyridinylimidazoles; inhibition of CSBP kinase.

J. Boehm, S. Kassis, John C. Lee, 1997, Bioorganic & medicinal chemistry.

New inhibitors of p38 kinase

J. Boehm, J. Adams, 2000 .

A symmetric inhibitor binds HIV-1 protease asymmetrically.

A M Hassell, R. DesJarlais, J. Boehm, 1993, Biochemistry.

Analytical approaches for quantification of a Nrf2 pathway activator: overcoming bioanalytical challenges to support a toxicity study.

J. Boehm, Catherine L. Booth-Genthe, J. Callahan, 2014, The Analyst.

p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases

J. Boehm, John C. Lee, Sanjay Kumar, 2003, Nature Reviews Drug Discovery.

Synthesis of water-soluble (aminoalkyl)camptothecin analogues: inhibition of topoisomerase I and antitumor activity.

J. Boehm, S. Hecht, R. Johnson, 1991, Journal of medicinal chemistry.

1-substituted 4-aryl-5-pyridinylimidazoles: a new class of cytokine suppressive drugs with low 5-lipoxygenase and cyclooxygenase inhibitory potency.

J. Boehm, J. Adams, T. Gallagher, 1996, Journal of medicinal chemistry.

Phenoxypyrimidine inhibitors of p38α kinase

Stephen R. Johnson, J. Boehm, M. Bower, 2001 .

Pyrimidinylimidazole inhibitors of CSBP/p38 kinase demonstrating decreased inhibition of hepatic cytochrome P450 enzymes.

J. Boehm, S. Kassis, J. Adams, 1998, Bioorganic & medicinal chemistry letters.

The synthesis and reactivity of 3β-(2-alkynylsulfonyl)- and 3β-(2-alkynylsulfonylmethyl) androst-5-en-17-ones as inhibitors of glucose-6-phosphate dehydrogenase

J. Boehm, J. Williams, 1995, Steroids.

The syntheses of 3β-steroidal diacylglyceryl sulfides, sulfoxides, and sulfones

J. Boehm, J. Williams, 1995, Steroids.

Pyrimidinylimidazole inhibitors of p38: cyclic N-1 imidazole substituents enhance p38 kinase inhibition and oral activity.

J. Boehm, S. Kassis, J. Adams, 2001, Bioorganic & medicinal chemistry letters.

Transport of antimicrobial agents using peptide carrier systems: anticandidal activity of m-fluorophenylalanine--peptide conjugates.

J. Boehm, W. Kingsbury, R. J. Mehta, 1983, Journal of medicinal chemistry.

1-substituted 4-aryl-5-pyridinylimidazoles: a new class of cytokine suppressive drugs with low 5-lipoxygenase and cyclooxygenase inhibitory potency.

J. Boehm, J. Adams, T. Gallagher, 1996, Journal of medicinal chemistry.

An improved and highly convergent synthesis of 4-substituted-pyrido[2,3-d]pyrimidin-7-ones

Zehong Wan, J. Boehm, J. Callahan, 2007 .

Rapid and convenient syntheses of polyoxin peptides containing N-methylated peptide bonds

J. Boehm, W. Kingsbury, 1986 .

Pyrimidinylimidazole inhibitors of CSBP/p38 kinase demonstrating decreased inhibition of hepatic cytochrome P450 enzymes.

D E Griswold, J. Boehm, S. Kassis, 1998, Bioorganic & medicinal chemistry letters.

Synthesis of water-soluble (aminoalkyl)camptothecin analogs: inhibition of topoisomerase I and antitumor activity

J. Boehm, R. Hertzberg, S. Hecht, 1991 .

Photochemistry of bicyclo[3.2.0]hept-3-en-2-ones

J. Boehm, M. R. Willcott, R. Cargill, 1973 .

Synthesis of alpha-thiophenylglycine peptides. Novel peptide substrates useful in the study of microbial peptide transport.

J. Boehm, W. Kingsbury, 2009, International journal of peptide and protein research.

TRANSPORT OF ANTIMICROBIAL AGENTS USING PEPTIDE CARRIER SYSTEMS: ANTICANDIDAL ACTIVITY OF M-FLUOROPHENYLALANINE-PEPTIDE CONJUGATES

J. Boehm, W. Kingsbury, R. J. Mehta, 1984 .

A novel peptide delivery system involving peptidase activated prodrugs as antimicrobial agents. Synthesis and biological activity of peptidyl derivatives of 5-fluorouracil.

J. Boehm, C. Gilvarg, W D Kingsbury, 1984, Journal of medicinal chemistry.

Synthesis of C2-symmetric and pseudosymmetric HIV-1 protease inhibitors from D-arabitol

J. Boehm, G. Dreyer, B. Chenera, 1991 .

Synthesis and LTB4 receptor antagonist activities of the naturally occurring LTB4 receptor antagonist Leucettamine A and related analogues.

J. Boehm, H. Sarau, J. Foley, 1993, Journal of medicinal chemistry.

Discovery of a crystalline sulforaphane analog with good solid-state stability and engagement of the Nrf2 pathway in vitro and in vivo.

J. Boehm, A. P. Graves, Shuping Dong, 2019, Bioorganic & medicinal chemistry.

5-Amino-2-carbonylthiophene derivatives for use as p38 MAPK inhibitors in the treatment of inflammatory diseases

J. Boehm, 2005 .

p38 mitogen-activated protein kinase inhibitors for the treatment of chronic cardiovascular disease.

J. Boehm, C. Angermann, C. Doe, 2003, Current opinion in investigational drugs.

3,5-Disubstituted-indole-7-carboxamides as IKKβ Inhibitors: Optimization of Oral Activity via the C3 Substituent.

J. Boehm, P. Bamborough, Wei-Chang Fu, 2018, ACS medicinal chemistry letters.

Phenoxypyrimidine inhibitors of p38alpha kinase: synthesis and statistical evaluation of the p38 inhibitory potencies of a series of 1-(piperidin-4-yl)-4-(4-fluorophenyl)-5-(2-phenoxypyrimidin-4-yl) imidazoles.

J. Boehm, M. Bower, S. Kassis, 2001, Bioorganic & medicinal chemistry letters.

Expert Opinion on Therapeutic Patents

J. Boehm, J. Adams, 2000 .

Discovery of Proline-Based p300/CBP Inhibitors Using DNA-Encoded Library Technology in Combination with High-Throughput Screening.

Douglas W. Thomson, Zhengrong Zhu, J. Boehm, 2022, Journal of medicinal chemistry.

Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis.

J. Boehm, John C. Lee, J. Adams, 2000, Arthritis and rheumatism.