M. Ascano

发表

Multi-disciplinary methods to define RNA-protein interactions and regulatory networks.

M. Ascano, S. Gerstberger, T. Tuschl, 2013, Current opinion in genetics & development.

Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP

Scott B. Dewell, M. Zavolan, M. Ascano, 2010, Cell.

Evolutionary conservation and expression of human RNA-binding proteins and their role in human genetic disease.

Thomas Tuschl, Markus Hafner, M. Ascano, 2014, Advances in experimental medicine and biology.

Regulation of Hedgehog signaling: a complex story.

M. Ascano, S. Ogden, D. Robbins, 2004, Biochemical pharmacology.

Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability.

Uwe Ohler, Stoyan Georgiev, Neelanjan Mukherjee, 2011, Molecular cell.

A novel computational biostatistics approach implies impaired dephosphorylation of growth factor receptors as associated with severity of autism

K. Wittkowski, M. Ascano, F. Shic, 2014, Translational Psychiatry.

Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA

M. Ascano, T. Tuschl, D. Patel, 2014, Cell reports.

Small molecule inhibition of human cGAS reduces total cGAMP output and cytokine expression in cells

M. Ascano, Byungil Kim, Caroline Wiser, 2020, Scientific Reports.

Conditions for Vigorous Growth on Sulfide and Reactor-Scale Cultivation Protocols for the Thermophilic Green Sulfur Bacterium Chlorobium tepidum

M. Ascano, Eric F. Johnson, B. Mukhopadhyay, 1999, Applied and Environmental Microbiology.

Enhancer of Rudimentary Homolog Affects the Replication Stress Response through Regulation of RNA Processing

M. Ascano, R. Zhao, D. Cortez, 2015, Molecular and Cellular Biology.

Identification of a Functional Interaction between the Transmembrane Protein Smoothened and the Kinesin-Related Protein Costal2

M. Ascano, S. Ogden, D. Robbins, 2003, Current Biology.

Smoothened Regulates Activator and Repressor Functions of Hedgehog Signaling via Two Distinct Mechanisms*

M. Ascano, T. Kornberg, S. Ogden, 2006, Journal of Biological Chemistry.

Viral crosslinking and solid-phase purification enables discovery of ribonucleoprotein complexes on incoming RNA virus genomes

M. Ascano, K. Rothamel, Byungil Kim, 2020, bioRxiv.

Multi-Disciplinary Methods to Define RNA-Protein Interactions and Their Regulatory Networks

M. Ascano, S. Gerstberger, T. Tuschl, 2013 .

Discovery of Widespread Host Protein Interactions with the Pre-replicated Genome of CHIKV Using VIR-CLASP.

M. Ascano, M. Garcia-Blanco, W. McDonald, 2020, Molecular cell.

Premature recruitment of oocyte pool and increased mTOR activity in Fmr1 knockout mice and reversal of phenotype with rapamycin

M. Ascano, T. Tuschl, A. Serganov, 2018, Scientific Reports.

Binding-Pocket and Lid-Regi on Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA Graphical

M. Ascano, T. Tuschl, D. Patel, 2014 .

Structure-Function Analysis of STING Activation by c[G(2′,5′)pA(3′,5′)p] and Targeting by Antiviral DMXAA

Roger A. Jones, M. Ascano, T. Tuschl, 2013, Cell.

Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase

Roger A. Jones, M. Ascano, T. Tuschl, 2013, Cell.

Eukaryote-specific insertion elements control human ARGONAUTE slicer activity.

M. Ascano, T. Tuschl, D. Patel, 2013, Cell reports.

FMR1 targets distinct mRNA sequence elements to regulate protein expression

Uwe Ohler, Neelanjan Mukherjee, Thomas Tuschl, 2012, Nature.

ELAVL1 primarily couples mRNA stability with the 3′ UTRs of interferon-stimulated genes

M. Ascano, K. Rothamel, N. Mukherjee, 2020, bioRxiv.

Pharmacological Activation of cGAS for Cancer Immunotherapy

M. Ascano, J. Balko, John T. Wilson, 2021, Frontiers in Immunology.

Identification of RNA–protein interaction networks using PAR‐CLIP

Thomas Tuschl, Markus Hafner, M. Ascano, 2012, Wiley interdisciplinary reviews. RNA.

RNA Binding Proteins as Pioneer Determinants of Infection: Protective, Proviral, or Both?

M. Ascano, K. Rothamel, Samantha M. Lisy, 2021, Viruses.

PAR-CLIP (Photoactivatable Ribonucleoside-Enhanced Crosslinking and Immunoprecipitation): a step-by-step protocol to the transcriptome-wide identification of binding sites of RNA-binding proteins.

M. Zavolan, M. Ascano, T. Tuschl, 2014, Methods in enzymology.

Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice

M. Ascano, T. Tuschl, D. Patel, 2017, Nature Communications.

Dual roles for the ER membrane protein complex in flavivirus infection: viral entry and protein biogenesis

M. Ascano, M. Garcia-Blanco, Byungil Kim, 2019, Scientific Reports.

Small molecule inhibition of human cGAS reduces total cGAMP output and cytokine expression in cells

M. Ascano, Byungil Kim, Caroline Wiser, 2020, Scientific Reports.

PAR-CliP - A Method to Identify Transcriptome-wide the Binding Sites of RNA Binding Proteins

Mohsen Khorshid, Mihaela Zavolan, Thomas Tuschl, 2010, Journal of visualized experiments : JoVE.

Endosomolytic Polymersomes Increase the Activity of Cyclic Dinucleotide STING Agonists to Enhance Cancer Immunotherapy

Mark Kelley, Dong Soo Yun, Daniel Shae, 2018, Nature Nanotechnology.

Costal2 Functions as a Kinesin-like Protein in the Hedgehog Signal Transduction Pathway

M. Ascano, A. Plessis, S. Ogden, 2008, Current Biology.

Costal 2 Functions as a Kinesin-like Protein in the Hedgehog Signal Transduction Pathway

M. Ascano, A. Plessis, S. Ogden, 2008 .

Dual roles for the ER membrane protein complex in flavivirus infection: viral entry and protein biogenesis

M. Ascano, M. Garcia-Blanco, Byungil Kim, 2019, Scientific Reports.

The Carboxyl-Terminal Domain of the Protein Kinase Fused Can Function as a Dominant Inhibitor of Hedgehog Signaling

M. Ascano, Kent E Nybakken, D. Robbins, 2002, Molecular and Cellular Biology.

Viral crosslinking and solid-phase purification enables discovery of ribonucleoprotein complexes on incoming RNA virus genomes

M. Ascano, K. Rothamel, Sarah Arcos, 2020, Nature Protocols.

A Quantification of Pathway Components Supports a Novel Model of Hedgehog Signal Transduction*

M. Ascano, S. Ogden, D. Robbins, 2009, The Journal of Biological Chemistry.

Premature recruitment of oocyte pool and increased mTOR activity in Fmr1 knockout mice and reversal of phenotype with rapamycin

M. Ascano, T. Tuschl, A. Serganov, 2018, Scientific Reports.

Multimeric assembly and biochemical characterization of the Trax/Translin endonuclease complex

M. Ascano, T. Tuschl, D. Patel, 2011, Nature Structural &Molecular Biology.

Augmented noncanonical BMP type II receptor signaling mediates the synaptic abnormality of fragile X syndrome

M. Ascano, T. Kornberg, P. Hagerman, 2016, Science Signaling.

M. Ascano, Kent E Nybakken, S. Ogden, 2004, Journal of Biological Chemistry.

G3BP1 enhances cytoplasmic DNA pattern recognition

M. Ascano, Byungil Kim, Caroline Wiser, 2018, Nature Immunology.

Publisher Correction: Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice

M. Ascano, T. Tuschl, D. Patel, 2017, Nature Communications.

An Intramolecular Association between Two Domains of the Protein Kinase Fused Is Necessary for Hedgehog Signaling

M. Ascano, D. Robbins, 2004, Molecular and Cellular Biology.

The Full-length Unprocessed Hedgehog Protein Is an Active Signaling Molecule*

M. Ascano, S. Kunes, D. Robbins, 2009, The Journal of Biological Chemistry.

Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice

M. Ascano, T. Tuschl, D. Patel, 2017, Nature Communications.

New insights in the mechanism of microRNA-mediated target repression

M. Ascano, T. Tuschl, M. Hafner, 2011, Nature Structural &Molecular Biology.

Title Augmented noncanonical BMP type II receptor signaling mediates the synaptic abnormality of fragile X syndrome

M. Ascano, T. Kornberg, P. Hagerman, 2016 .

type receptor signaling mediates the abnormality fragile X syndrome.

M. Ascano, P. Hagerman, R. Hagerman, 2016 .

Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase

Roger A. Jones, M. Ascano, T. Tuschl, 2013, Cell.

G3BP1 enhances cytoplasmic DNA pattern recognition

M. Ascano, Byungil Kim, Caroline Wiser, 2018, Nature Immunology.