V. Quesada

发表

Arabidopsis mTERF6 is required for leaf patterning.

P. Robles, E. Núñez-Delegido, A. Ferrández-Ayela, 2018, Plant science : an international journal of experimental plant biology.

Non-coding recurrent mutations in chronic lymphocytic leukaemia

A. Valencia, X. Estivill, D. Torrents, 2015, Nature.

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

Juliane C. Dohm, A. Valencia, R. Guigó, 2011, Nature.

The Common Marmoset Genome Provides Insight into Primate Biology and Evolution

Albert J. Vilella, Charles E. Vejnar, Matthew W. Hahn, 2014, Nature Genetics.

Comparative and demographic analysis of orang-utan genomes

Albert J. Vilella, Zhengyuan O. Wang, Matthew W. Hahn, 2011, Nature.

Polyserase-I, a human polyprotease with the ability to generate independent serine protease domains from a single translation product

Santiago Cal, V. Quesada, C. López-Otín, 2003, Proceedings of the National Academy of Sciences of the United States of America.

International network of cancer genome projects

Gary D Bader, Benjamin J. Raphael, Joshua M. Stuart, 2010, Nature.

The genome of a songbird

Albert J. Vilella, Andreas R. Pfenning, Miriam K. Konkel, 2010, Nature.

A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing

Michael C. Heinold, David T. W. Jones, Timothy A Beck, 2015, Nature Communications.

Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia

E. Giné, A. Valencia, X. Estivill, 2011, Nature Genetics.

Extreme genomic erosion after recurrent demographic bottlenecks in the highly endangered Iberian lynx

M. Tress, J. Rodriguez, A. Valencia, 2016, Genome Biology.

POT1 loss-of-function variants predispose to familial melanoma

Thomas M. Keane, K. Brown, D. Bishop, 2014, Nature Genetics.

POT1 mutations cause telomere dysfunction in chronic lymphocytic leukemia

A. López-Guillermo, E. Campo, A. Martínez-Trillos, 2013, Nature Genetics.

Deubiquitinases in cancer: new functions and therapeutic options

V. Quesada, C. López-Otín, J. Freije, 2012, Oncogene.

Unravelling Gene Function Through Mutagenesis

P. Robles, V. Quesada, Andrea Hricová, 2010 .

leukemia major molecular and clinical subdivision in chronic lymphocytic Transcriptome characterization by RNA sequencing identifies a Material

Pedro G. Ferreira, Panagiotis K. Papasaikas, David G. Knowles, 2014 .

A Functional Ubiquitin-Specific Protease Embedded in the Large Tegument Protein (ORF64) of Murine Gammaherpesvirus 68 Is Active during the Course of Infection

V. Quesada, H. Ploegh, E. Spooner, 2007, Journal of Virology.

Apicomplexan UCHL3 retains dual specificity for ubiquitin and Nedd8 throughout evolution

V. Quesada, H. Ploegh, E. Frickel, 2007, Cellular microbiology.

Matriptase-2 mutations in iron-refractory iron deficiency anemia patients provide new insights into protease activation mechanisms.

V. Quesada, C. López-Otín, G. Velasco, 2009, Human molecular genetics.

Differential mechanisms of tolerance to extreme environmental conditions in tardigrades

V. Quesada, C. López-Otín, J. Pérez-Silva, 2019, Scientific Reports.

Transcriptome characterization by RNA sequencing identifies a major molecular and clinical subdivision in chronic lymphocytic leukemia

Alfonso Valencia, David Tamborero, Daniel Rico, 2014, Genome research.

Mutations in the plant-conserved MTERF9 alter chloroplast gene expression, development and tolerance to abiotic stress in Arabidopsis thaliana.

P. Robles, J. Micol, V. Quesada, 2015, Physiologia plantarum.

Both abscisic acid (ABA)-dependent and ABA-independent pathways govern the induction of NCED3, AAO3 and ABA1 in response to salt stress.

J. Micol, V. Quesada, P. L. Rodriguez, 2006, Plant, cell & environment.

Frequent birth-and-death events throughout perforin-1 evolution

V. Quesada, Miguel Araujo-Voces, 2020, BMC evolutionary biology.

Organelle Genetics in Plants

P. Robles, V. Quesada, 2021, International journal of molecular sciences.

Next-generation sequencing reveals the secrets of the chronic lymphocytic leukemia genome

P. Jares, V. Quesada, D. Rodríguez, 2012, Clinical and Translational Oncology.

Sequence variation at KLK and WFDC clusters and its association to semen hyperviscosity and other male infertility phenotypes.

V. Quesada, Diana A. Puente, R. Matthiesen, 2016, Human reproduction.

Genetic analysis of salt-tolerant mutants in Arabidopsis thaliana.

J. Micol, V. Quesada, M. Ponce, 2000, Genetics.

Mutations in the RETICULATA gene dramatically alter internal architecture but have little effect on overall organ shape in Arabidopsis leaves.

P. Robles, J. Micol, V. Quesada, 2006, Journal of experimental botany.

Chronic lymphocytic leukemia with SF3B1 mutation.

V. Quesada, C. López-Otín, A. Ramsay, 2012, The New England journal of medicine.

Chapter 412 – Cathepsin O

V. Quesada, C. López-Otín, G. Velasco, 2013 .

Insights into the Evolution of Longevity from the Bowhead Whale Genome

N. Grishin, G. Church, J. George, 2015, Cell reports.

Progerin accelerates atherosclerosis by inducing endoplasmic reticulum stress in vascular smooth muscle cells

T. Misteli, V. Quesada, C. López-Otín, 2019, EMBO molecular medicine.

Cystatin D is a candidate tumor suppressor gene induced by vitamin D in human colon cancer cells.

V. Quesada, C. López-Otín, A. Muñoz, 2009, The Journal of clinical investigation.

Comparative genomics of mortal and immortal cnidarians unveils novel keys behind rejuvenation

V. Quesada, C. López-Otín, D. Rodríguez, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Identification and characterization of ADAMTS-20 defines a novel subfamily of metalloproteinases-disintegrins with multiple thrombospondin-1 repeats and a unique GON domain.

V. Quesada, C. López-Otín, S. Cal, 2003, The Journal of Biological Chemistry.

Identification and Characterization of ADAMTS-20 Defines a Novel Subfamily of Metalloproteinases-Disintegrins with Multiple Thrombospondin-1 Repeats and a Unique GON Domain*

V. Quesada, C. López-Otín, S. Cal, 2003, The Journal of Biological Chemistry.

Nonsense mutations in the shelterin complex genes ACD and TERF2IP in familial melanoma.

Thomas M. Keane, K. Brown, J. Trent, 2015, Journal of the National Cancer Institute.

CiberAMP: An R Package to Identify Differential mRNA Expression Linked to Somatic Copy Number Variations in Cancer Datasets

V. Quesada, A. Carracedo, X. Bustelo, 2022, Biology.

A Functional Ubiquitin-Speciﬁc Protease Embedded in the Large Tegument Protein (ORF64) of Murine Gammaherpesvirus 68 Is Active during the Course of Infection (cid:1)

V. Quesada, H. Ploegh, E. Spooner, 2007 .

Rapid discrimination of sequences flanking and within T-DNA insertions in the Arabidopsis genome.

J. Micol, V. Quesada, M. Ponce, 1998, The Plant journal : for cell and molecular biology.

RNA processing and Arabidopsis flowering time control.

R. Macknight, V. Quesada, I. Henderson, 2004, Biochemical Society transactions.

Autophagy‐linked plasma and lysosomal membrane protein PLAC8 is a key host factor for SARS‐CoV‐2 entry into human cells

V. Quesada, C. López-Otín, J. Freije, 2022, The EMBO journal.

Unveiling the functions of plastid ribosomal proteins in plant development and abiotic stress tolerance.

P. Robles, V. Quesada, 2022, Plant physiology and biochemistry : PPB.

FY Is an RNA 3′ End-Processing Factor that Interacts with FCA to Control the Arabidopsis Floral Transition

V. Quesada, I. Henderson, C. Dean, 2003, Cell.

Analysis of ven3 and ven6 reticulate mutants reveals the importance of arginine biosynthesis in Arabidopsis leaf development.

P. Robles, Raquel Sarmiento-Mañús, J. Micol, 2011, The Plant journal : for cell and molecular biology.

The Degradome database: mammalian proteases and diseases of proteolysis

Gonzalo R. Ordóñez, Víctor Quesada, Luis M. Sánchez, 2008, Nucleic Acids Res..

Altered patterns of global protein synthesis and translational fidelity in RPS15-mutated chronic lymphocytic leukemia.

S. Gygi, A. López-Guillermo, E. Campo, 2018, Blood.

Giant tortoise genomes provide insights into longevity and age-related disease

K. White, T. Marquès-Bonet, V. Quesada, 2018, Nature Ecology & Evolution.

Arabidopsis RUGOSA2 encodes an mTERF family member required for mitochondrion, chloroplast and leaf development.

Raquel Sarmiento-Mañús, J. Micol, V. Quesada, 2011, The Plant journal : for cell and molecular biology.

Adaptive Evolution Favoring KLK4 Downregulation in East Asians.

V. Quesada, P. Marques, S. Seixas, 2016, Molecular biology and evolution.

Regulated RNA processing in the control of Arabidopsis flowering.

V. Quesada, C. Dean, G. Simpson, 2005, The International journal of developmental biology.

The Arabidopsis RNA-binding protein FCA requires a lysine-specific demethylase 1 homolog to downregulate FLC.

V. Quesada, C. Dean, S. Swiezewski, 2007, Molecular cell.

The genomic landscape of chronic lymphocytic leukemia: clinical implications

E. Campo, V. Quesada, X. Puente, 2013, BMC Medicine.

Association of the POT1 Germline Missense Variant p.I78T With Familial Melanoma

S. Puig, D. Bishop, V. Quesada, 2019, JAMA dermatology.

Identification and Characterization of Human Archaemetzincin-1 and -2, Two Novel Members of a Family of Metalloproteases Widely Distributed in Archaea*

Víctor Quesada, Carlos López-Otín, Araceli Díaz-Perales, 2005, Journal of Biological Chemistry.

USP39 Deubiquitinase Is Essential for KRAS Oncogene-driven Cancer*

S. Lowe, V. Quesada, C. López-Otín, 2017, The Journal of Biological Chemistry.

Molecular pathogenesis of CLL and its evolution

Víctor Quesada, Carlos López-Otín, Elias Campo, 2015, International Journal of Hematology.

Structural and Enzymatic Characterization of Drosophila Dm2-MMP, a Membrane-bound Matrix Metalloproteinase with Tissue-specific Expression*

V. Quesada, C. López-Otín, S. Noselli, 2002, The Journal of Biological Chemistry.

CANCERTOOL: A Visualization and Representation Interface to Exploit Cancer Datasets.

Iñigo Apaolaza, Francisco J. Planes, Ana M. Aransay, 2018, Cancer research.

Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia

Alfonso Valencia, Modesto Orozco, Brandy Klotzle, 2012, Nature Genetics.

Autoregulation of FCA pre‐mRNA processing controls Arabidopsis flowering time

R. Macknight, V. Quesada, C. Dean, 2003, The EMBO journal.

Mutations in TLR/MYD88 pathway identify a subset of young chronic lymphocytic leukemia patients with favorable outcome.

E. Giné, A. López-Guillermo, E. Campo, 2014, Blood.

Identification and Characterization of Human and Mouse Ovastacin

Víctor Quesada, Carlos López-Otín, V. Quesada, 2004, Journal of Biological Chemistry.

The roles of mitochondrial transcription termination factors (MTERFs) in plants.

V. Quesada, 2016, Physiologia plantarum.

Research Progress in the Molecular Functions of Plant mTERF Proteins

P. Robles, V. Quesada, 2021, Cells.

Supplemental Section S1 – Genome Sequencing and Assembly........................................... 2 Supplemental Section S2 – Indel Assessment with the Neutral Indel Model ................11 Supplemental Section S3 – Great Ape Divergence Estimate via Wgs Read Mapping..11 Supplemental Section S7 –

Albert J. Vilella, Zhengyuan O. Wang, Miriam K. Konkel, 2022 .

A Comprehensive Assessment of Somatic Mutation Calling in Cancer Genomes

Roland Eils, Pablo H. Hennings-Yeomans, Paul T. Spellman, 2014, bioRxiv.

Cell–cell adhesion genes CTNNA2 and CTNNA3 are tumour suppressors frequently mutated in laryngeal carcinomas

Víctor Quesada, Carlos López-Otín, Santiago Cal, 2013, Nature Communications.

Mutations in CHD2 cause defective association with active chromatin in chronic lymphocytic leukemia.

A. López-Guillermo, E. Campo, N. Villamor, 2015, Blood.

Recurrent gene mutations in CLL.

E. Campo, N. Villamor, V. Quesada, 2013, Advances in experimental medicine and biology.

Human Polyserase-2, a Novel Enzyme with Three Tandem Serine Protease Domains in a Single Polypeptide Chain*

V. Quesada, C. López-Otín, S. Cal, 2005, Journal of Biological Chemistry.

Identification of Human Aminopeptidase O, a Novel Metalloprotease with Structural Similarity to Aminopeptidase B and Leukotriene A4 Hydrolase*

V. Quesada, C. López-Otín, A. Díaz‐Perales, 2005, Journal of Biological Chemistry.

Mutations in CHD 2 cause defective association with active chromatin in chronic lymphocytic leukemia

A. López-Guillermo, E. Campo, N. Villamor, 2015 .

Genetic Architecture of NaCl Tolerance in Arabidopsis1

J. Micol, V. Quesada, M. Ponce, 2002, Plant Physiology.

Arabidopsis MDA1, a Nuclear-Encoded Protein, Functions in Chloroplast Development and Abiotic Stress Responses

P. Robles, J. Micol, V. Quesada, 2012, PloS one.

Human Autophagins, a Family of Cysteine Proteinases Potentially Implicated in Cell Degradation by Autophagy*

Xose S. Puente, V. Quesada, X. Puente, 2003, The Journal of Biological Chemistry.

Matriptase-2, a Membrane-bound Mosaic Serine Proteinase Predominantly Expressed in Human Liver and Showing Degrading Activity against Extracellular Matrix Proteins*

V. Quesada, C. López-Otín, G. Velasco, 2002, The Journal of Biological Chemistry.

Lessons from a search for leaf mutants in Arabidopsis thaliana.

P. Robles, J. Micol, V. Quesada, 2009, The International journal of developmental biology.

Exome sequencing and functional analysis identifies BANF1 mutation as the cause of a hereditary progeroid syndrome.

V. Quesada, X. Puente, Diana A. Puente, 2011, American journal of human genetics.

Functional analysis of sucrase-isomaltase mutations from chronic lymphocytic leukemia patients.

E. Campo, V. Quesada, C. López-Otín, 2013, Human molecular genetics.

Transcriptional and Post-transcriptional Regulation of Organellar Gene Expression (OGE) and Its Roles in Plant Salt Tolerance

P. Robles, V. Quesada, 2019, International journal of molecular sciences.

Sexual and Apogamous Species of Woodferns Show Different Protein and Phytohormone Profiles

V. Quesada, U. Grossniklaus, J. Grossmann, 2021, Frontiers in Plant Science.

Frequent somatic mutations in components of the RNA processing machinery in chronic lymphocytic leukemia

J. Valcárcel, A. López-Guillermo, E. Campo, 2013, Leukemia.

NOTCH1 mutations identify a genetic subgroup of chronic lymphocytic leukemia patients with high risk of transformation and poor outcome

E. Giné, A. López-Guillermo, E. Campo, 2013, Leukemia.

Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases.

Víctor Quesada, Carlos López-Otín, Araceli Díaz-Perales, 2004, Biochemical and biophysical research communications.

The Novel Evolution of the Sperm Whale Genome

Troy J. Kieran, T. Marquès-Bonet, V. Quesada, 2017, Genome biology and evolution.

Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains.

Víctor Quesada, Carlos López-Otín, Santiago Cal, 2002, Gene.

Research articleComparative genomic analysis of the zebra finch degradome provides new insights into evolution of proteases in birds and mammals

V. Quesada, C. López-Otín, G. Velasco, 2016 .

Comparative genomic analysis of the zebra finch degradome provides new insights into evolution of proteases in birds and mammals

V. Quesada, C. López-Otín, G. Velasco, 2010, BMC Genomics.

Proteolytic systems: constructing degradomes.

V. Quesada, C. López-Otín, G. R. Ordóñez, 2009, Methods in molecular biology.

Identification and characterization of human polyserase-3, a novel protein with tandem serine-protease domains in the same polypeptide chain

V. Quesada, C. López-Otín, S. Cal, 2006, BMC Biochemistry.

Identification and Enzymatic Characterization of Two Diverging Murine Counterparts of Human Interstitial Collagenase (MMP-1) Expressed at Sites of Embryo Implantation*

V. Quesada, C. López-Otín, M. Balbín, 2001, The Journal of Biological Chemistry.

The Degradome database: expanding roles of mammalian proteases in life and disease

José G. Pérez-Silva, Víctor Quesada, Yaiza Español, 2015, Nucleic Acids Res..

Novel LMNA mutations cause an aggressive atypical neonatal progeria without progerin accumulation

V. Quesada, Diana A. Puente, C. López-Otín, 2016, Journal of Medical Genetics.

Genetic architecture of leaf morphogenesis in Arabidopsis thaliana

P. Robles, J. Micol, V. Quesada, 2001 .

OTC and AUL1, two convergent and overlapping genes in the nuclear genome of Arabidopsis thaliana

J. Micol, V. Quesada, M. Ponce, 1999, FEBS letters.

nVenn: generalized, quasi‐proportional Venn and Euler diagrams

Víctor Quesada, José G. Pérez-Silva, Miguel Araujo-Voces, 2018, Bioinform..

PORPHOBILINOGEN DEAMINASE Deficiency Alters Vegetative and Reproductive Development and Causes Lesions in Arabidopsis

Raquel Sarmiento-Mañús, J. Micol, V. Quesada, 2013, PloS one.

Development of a CRISPR/Cas9-based therapy for Hutchinson-Gilford progeria syndrome

V. Quesada, C. López-Otín, S. Nourshargh, 2019, Nature Medicine.

Emerging Roles of Mitochondrial Ribosomal Proteins in Plant Development

P. Robles, V. Quesada, 2017, International journal of molecular sciences.

Whole-genome sequencing identifies recurrent mutations in chronic lymphocyticleukaemia

A. Valencia, R. Guigó, X. Estivill, 2011 .

The Characterization of Arabidopsis mterf6 Mutants Reveals a New Role for mTERF6 in Tolerance to Abiotic Stress

P. Robles, E. Núñez-Delegido, A. Ferrández-Ayela, 2018, International journal of molecular sciences.

The SCABRA3 Nuclear Gene Encodes the Plastid RpoTp RNA Polymerase, Which Is Required for Chloroplast Biogenesis and Mesophyll Cell Proliferation in Arabidopsis1[W]

J. Micol, V. Quesada, A. Hricová, 2006, Plant Physiology.

Unveiling plant mTERF functions.

P. Robles, J. Micol, V. Quesada, 2012, Molecular plant.

Arabidopsis Plastid-RNA Polymerase RPOTp Is Involved in Abiotic Stress Tolerance

P. Robles, E. Núñez-Delegido, V. Quesada, 2020, Plants.

The SCABRA 3 Nuclear Gene Encodes the Plastid RpoTp RNA Polymerase , Which Is Required for Chloroplast Biogenesis and Mesophyll Cell Proliferation in Arabidopsis 1 [ W ]

J. Micol, V. Quesada, A. Hricová, 2006 .

Analysis of Arabidopsis venosa4-0 supports the role of VENOSA4 in dNTP homeostasis

Raquel Sarmiento-Mañús, J. Micol, V. Quesada, 2023, bioRxiv.

Reply to Miglietta: Toward doing rigorous and innovative science with nonmodel organisms

V. Quesada, Maria Pascual-Torner, 2023, Proceedings of the National Academy of Sciences of the United States of America.

Noncanonical Translation Initiation of the Arabidopsis Flowering Time and Alternative Polyadenylation Regulator FCA[C][W]

R. Macknight, V. Quesada, C. Dean, 2010, Plant Cell.

Exome sequencing identifies a novel mutation in PIK3R1 as the cause of SHORT syndrome

V. Quesada, Diana A. Puente, C. López-Otín, 2014, BMC Medical Genetics.

The ABA1 gene and carotenoid biosynthesis are required for late skotomorphogenic growth in Arabidopsis thaliana.

J. Micol, V. Quesada, P. L. Rodriguez, 2007, Plant, cell & environment.

Withdrawal: Identification and characterization of human and mouse ovastacin: A novel metalloproteinase similar to hatching enzymes from arthropods, birds, amphibians, and fish.

V. Quesada, C. López-Otín, L. M. Sánchez, 2019, Journal of Biological Chemistry.

The common marmoset genome provides insight into primate biology and evolution

Albert J. Vilella, Charles E. Vejnar, Miriam K. Konkel, 2014, Nature Genetics.

Acyl coenzyme A binding protein (ACBP): An aging‐ and disease‐relevant “autophagy checkpoint”

V. Quesada, C. López-Otín, G. Kroemer, 2023, Aging cell.

Advances in the Molecular Mechanisms of Abscisic Acid and Gibberellins Functions in Plants

V. Quesada, 2021, International journal of molecular sciences.

Advances in the Molecular Mechanisms of Abscisic Acid and Gibberellins Functions in Plants 2.0

V. Quesada, 2022, International journal of molecular sciences.

Human Autophagins, a Family of Cysteine Proteinases Potentially Implicated in Cell Degradation by Autophagy*

V. Quesada, X. Puente, C. López-Otín, 2003, The Journal of Biological Chemistry.

CANCERTOOL: A Visualization and Representation Interface to Exploit Cancer Datasets.

V. Quesada, R. Gomis, Iñigo Apaolaza, 2018, Cancer research.

Exome sequencing and functional analysis identifies BANF1 mutation as the cause of a hereditary progeroid syndrome.

V. Quesada, X. Puente, Diana A. Puente, 2011, American journal of human genetics.

POT1 loss-of-function variants predispose to familial melanoma

V. Quesada, C. López-Otín, K. Pooley, 2014, Nature Genetics.