M. Fischer

发表

Genomewide association analysis of coronary artery disease.

C. Gieger, P. Deloukas, M. Tobin, 2007, The New England journal of medicine.

Genetic linkage and association of the growth hormone secretagogue receptor (ghrelin receptor) gene in human obesity.

M. Olivier, J. Erdmann, M. Fischer, 2005, Diabetes.

Validation of the DAPT score in patients randomized to 6 or 12 months clopidogrel after predominantly second-generation drug-eluting stents

M. Fischer, H. Schunkert, A. Kastrati, 2017, Thrombosis and Haemostasis.

New susceptibility locus for coronary artery disease on chromosome 3q22.3

Benjamin J. Wright, A. Peters, P. Deloukas, 2009, Nature Genetics.

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

Thomas W. Mühleisen, Benjamin J. Wright, C. Gieger, 2011, Nature Genetics.

Ticagrelor or Prasugrel in Patients with Acute Coronary Syndromes.

W. Rottbauer, M. Fischer, H. Schunkert, 2019, The New England journal of medicine.

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

John Spertus, Markus Perola, Eric Boerwinkle, 2012, The Lancet.

Repeated Replication and a Prospective Meta-Analysis of the Association Between Chromosome 9 p 21 . 3 and Coronary Artery Disease

Ludwig A Hothorn, Nilesh J Samani, Andreas Ziegler, 2008 .

Correction: Lifelong Reduction of LDL-Cholesterol Related to a Common Variant in the LDL-Receptor Gene Decreases the Risk of Coronary Artery Disease—A Mendelian Randomisation Study

C. Gieger, F. Kronenberg, A. Peters, 2008, PLoS ONE.

Angiotensin-converting enzyme inhibitors in preventing remodeling and development of heart failure after acute myocardial infarction: results of the German multicenter study of the effects of captopril on cardiopulmonary exercise parameters (ECCE).

M. Fischer, G. Sabin, U. Winter, 1997, The American journal of cardiology.

Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors

M. Fischer, J. Lewicki, A. Gurney, 2012, Proceedings of the National Academy of Sciences.

Cardiovascular phenotypes and functional parameters in the general population--results of the MONICA/KORA studies.

C. Hengstenberg, M. Fischer, H. Schunkert, 2005, Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)).

Long-Term Survival in Adult Patients With Severe Acute Lung Failure Receiving Veno-Venous Extracorporeal Membrane Oxygenation.

M. Fischer, T. Bein, A. Philipp, 2017, Critical care medicine.

Six Versus Twelve Months Clopidogrel Therapy After Drug-Eluting Stenting in Patients With Acute Coronary Syndrome: An ISAR-SAFE Study Subgroup Analysis

M. Fischer, H. Schunkert, A. Kastrati, 2016, Scientific Reports.

Long-term effects of in-hospital cardiac rehabilitation on the cardiac risk profile. A case-control study in pairs of siblings with myocardial infarction.

C. Hengstenberg, M. Fischer, A. Baessler, 2001, European heart journal.

Anti-DLL4 inhibits growth and reduces tumor-initiating cell frequency in colorectal tumors with oncogenic KRAS mutations.

M. Fischer, J. Lewicki, A. Gurney, 2011, Cancer research.

Lack of association of a 9 bp insertion/deletion polymorphism within the bradykinin 2 receptor gene with myocardial infarction.

H. Hense, J. Erdmann, C. Hengstenberg, 2004, Clinical science.

Relation of the G Protein &bgr;3-Subunit Polymorphism With Left Ventricle Structure and Function

H. Hense, J. Erdmann, C. Hengstenberg, 2002, Hypertension.

Mannose-binding lectin in obesity with different degrees of metabolic syndrome abnormalities: association with atherogenic and metabolic traits.

M. Fischer, A. Baessler, G. Schmitz, 2012, Journal of atherosclerosis and thrombosis.

Association of angiotensin-converting enzyme 2 (ACE2) gene polymorphisms with parameters of left ventricular hypertrophy in men

I. König, J. Erdmann, C. Hengstenberg, 2005, Journal of Molecular Medicine.

Association between PPAR-alpha gene polymorphisms and myocardial infarction

Katharina, J. Erdmann, C. Hengstenberg, 2020 .

Coronary Artery Ectasia Are Frequently Observed in Patients With Bicuspid Aortic Valves With and Without Dilatation of the Ascending Aorta

J. Erdmann, C. Hengstenberg, M. Fischer, 2016, Circulation. Cardiovascular interventions.

Common polymorphisms in the cannabinoid CB2 receptor gene (CNR2) are not associated with myocardial infarction and cardiovascular risk factors.

S. Wiedmann, J. Erdmann, C. Hengstenberg, 2008, International journal of molecular medicine.

Abstract 1907: Wnt pathway antagonist OMP-54F28 (FZD8-Fc) inhibits tumor growth and reduces tumor-initiating cell frequency in patient-derived hepatocellular carcinoma and ovarian cancer xenograft models

M. Fischer, J. Lewicki, A. Gurney, 2014 .

Abstract A30: Predictive and pharmacodynamic biomarkers of vantictumab (OMP-18R5; anti-Frizzled) in non-small cell lung cancer

M. Fischer, J. Lewicki, T. Hoey, 2015 .

No association of interleukin-6 gene polymorphism (-174 G/C) with myocardial infarction or traditional cardiovascular risk factors.

J. Erdmann, C. Hengstenberg, Bjoern Mayer, 2004, International journal of cardiology.

BNP as a marker of diastolic dysfunction in the general population: Importance of left ventricular hypertrophy

M. Fischer, H. Schunkert, A. Döring, 2005, European journal of heart failure.

Genetic Variants Within the LPIN1 Gene, Encoding Lipin, Are Influencing Phenotypes of the Metabolic Syndrome in Humans

S. Wiedmann, C. Hengstenberg, M. Fischer, 2008, Diabetes.

Randomized, Double Blind Trial of 6 Versus 12 Months Of Dual Antiplatelet Therapy After DES-Implantation (ISAR-SAFE)

C. Hengstenberg, M. Fischer, H. Schunkert, 2014 .

Lack of a high prevalence of the BB vitamin D receptor genotype in severely osteoporotic women.

M. Fischer, J. Wergedal, D. Baylink, 1995, The Journal of clinical endocrinology and metabolism.

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

Alberto Piazza, William Matthai, Flora Peyvandi, 2009, Nature Genetics.

Association of angiotensin-converting enzyme 2 (ACE2) gene polymorphisms with parameters of left ventricular hypertrophy in men

I. König, J. Erdmann, C. Hengstenberg, 2005, Journal of Molecular Medicine.

Large-Scale Candidate Gene Analysis of HDL Particle Features

Paul R. Burton, Nilesh J. Samani, Hans Robert Kalbitzer, 2011, PloS one.

The lipoprotein subfraction profile: heritability and identification of quantitative trait loci Published, JLR Papers in Press, December 28, 2007.

Hans Robert Kalbitzer, Heribert Schunkert, Klaus Stark, 2008, Journal of Lipid Research.

Anti-DLL4 HasBroad SpectrumActivityinPancreatic Cancer DependentonTargetingDLL4-NotchSignalinginBothTumor and Vasculature Cells

Edward J. Kim, M. Fischer, J. Lewicki, 2012 .

Lack of Association Between the MEF2A Gene and Myocardial Infarction Genetics

I. König, A. Ziegler, J. Erdmann, 2008 .

Lack of Association Between the MEF 2 A Gene and Myocardial Infarction

I. König, A. Ziegler, J. Erdmann, 2007 .

Bail-Out Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy in a Patient With Takotsubo Cardiomyopathy-Induced Cardiogenic Shock.

M. Fischer, L. Maier, S. Sossalla, 2019, Circulation. Cardiovascular interventions.

M. Fischer, B. Sinner, D. Camboni, 2019, BMJ Open.

Large-Scale Gene-Centric Analysis Identifies Novel Variants for Coronary Artery Disease

Simon C. Potter, Thomas W. Mühleisen, Benjamin J. Wright, 2011, PLoS genetics.

[Is the aorto-coronary bypass operation useful in patients with advanced coronary sclerosis and poor ventricular function?].

M. Fischer, M. Turina, H. Hirzel, 1982, Schweizerische medizinische Wochenschrift.

Lifelong Reduction of LDL-Cholesterol Related to a Common Variant in the LDL-Receptor Gene Decreases the Risk of Coronary Artery Disease—A Mendelian Randomisation Study

C. Gieger, F. Kronenberg, A. Peters, 2008, PloS one.

Association of Common Polymorphisms in GLUT9 Gene with Gout but Not with Coronary Artery Disease in a Large Case-Control Study

S. Wiedmann, J. Erdmann, C. Hengstenberg, 2008, PloS one.

The polymorphism of the vitamin D-binding protein (Gc); Isoelectric focusing in 3 M urea as additional method for identification of genetic variants

M. Fischer, R. Kirk, D. Dykes, 1983, Human Genetics.

Edinburgh Research Explorer Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Tom R. Gaunt, Andrew D. Johnson, Nicholette D. Palmer, 2022 .

Targeting Notch Signaling with a Notch2/Notch3 Antagonist (Tarextumab) Inhibits Tumor Growth and Decreases Tumor-Initiating Cell Frequency

M. Fischer, J. Lewicki, A. Gurney, 2015, Clinical Cancer Research.

Intratumoral heterogeneity generated by Notch signaling promotes small cell lung cancer

K. Garcia, M. Fischer, J. Sage, 2017, Nature.

RSPO3 antagonism inhibits growth and tumorigenicity in colorectal tumors harboring common Wnt pathway mutations

M. Fischer, T. Hoey, F. Cattaruzza, 2017, Scientific Reports.

Lack of Association Between the Trp 719 Arg Polymorphism in Kinesin-Like Protein-6 and Coronary Artery Disease in 19 Case-Control

Alexander F. Wilson, A. F. Wilson, D. Absher, 2017 .

Protein-6 and Coronary Artery Disease in 19 Case-Control Studies Lack of Association Between the Trp719Arg Polymorphism in Kinesin-Like

Alexander F. Wilson, A. F. Wilson, D. Absher, 2012 .

Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies.

Alexander F. Wilson, A. F. Wilson, Benjamin J. Wright, 2010, Journal of the American College of Cardiology.

P Lack of Association Between the Trp 719 Arg Polymorphism in Kinesin-Like Protein-6 and Coronary Artery Disease in 19 Case-Control Studies

Alexander F. Wilson, A. F. Wilson, D. Absher, 2010 .

Systematic analysis of variants related to familial hypercholesterolemia in families with premature myocardial infarction

T. Wieland, J. Erdmann, C. Hengstenberg, 2015, European Journal of Human Genetics.

Whole-exome sequencing in an extended family with myocardial infarction unmasks familial hypercholesterolemia

P. Deloukas, J. Erdmann, C. Hengstenberg, 2014, BMC Cardiovascular Disorders.

Dysfunctional nitric oxide signalling increases risk of myocardial infarction

M. Nöthen, J. Ott, N. Samani, 2013, Nature.

WNT antagonists exhibit unique combinatorial antitumor activity with taxanes by potentiating mitotic cell death

M. Fischer, J. Lewicki, A. Gurney, 2017, Science Advances.

Abstract 4367: Discovery and evaluation of pharmacodynamic and predictive biomarkers for anti-RSPO3, a treatment that reduces tumor growth and cancer stem cell frequency in patient derived xenograft tumor models

M. Fischer, J. Lewicki, A. Gurney, 2015 .

Lack of Association Between a Common Polymorphism Near the INSIG2 Gene and BMI, Myocardial Infarction, and Cardiovascular Risk Factors

S. Wiedmann, J. Erdmann, C. Hengstenberg, 2009, Obesity.

Abstract 4652: Effects of anti-DLL4 treatment on non-small cell lung cancer (NSCLC) human xenograft tumors

M. Fischer, J. Lewicki, A. Gurney, 2016 .

Anti-DLL4 Has Broad Spectrum Activity in Pancreatic Cancer Dependent on Targeting DLL4-Notch Signaling in Both Tumor and Vasculature Cells

Edward J. Kim, M. Fischer, J. Lewicki, 2012, Clinical Cancer Research.

The standing of percutaneous pulmonary valve implantation compared to surgery in a non-preselected cohort with dysfunctional right ventricular outflow tract - Reasons for failure and contraindications.

M. Fischer, U. Blanz, N. Haas, 2019, Journal of cardiology.

Type II Secretory Phospholipase A2 and Prognosis in Patients with Stable Coronary Heart Disease: Mendelian Randomization Study

H. Brenner, C. Hengstenberg, M. Fischer, 2011, PloS one.

Distinct Heritable Patterns of Angiographic Coronary Artery Disease in Families With Myocardial Infarction

J. Erdmann, C. Hengstenberg, Bjoern Mayer, 2005, Circulation.

Alterations of Plasma Lysophosphatidylcholine Species in Obesity and Weight Loss

M. Fischer, A. Baessler, G. Schmitz, 2014, PloS one.

Association of Polymorphisms of the Apolipoprotein(a) Gene With Lipoprotein(a) Levels and Myocardial Infarction

C. Hengstenberg, M. Fischer, H. Schunkert, 2003, Circulation.

Abstract 3357: Targeting cancer stem cells by an anti-DLL4 antibody inhibits epithelial-to-mesenchymal transition, delays tumor recurrence and overcomes drug resistance in breast and pancreatic cancer

M. Fischer, J. Lewicki, A. Gurney, 2012 .

Abstract 2834: Anti-DLL4 treatment inhibits melanoma tumor growth, recurrence, metastases, and reduces frequency of cancer stem cells in a clinically relevant tumor model in NOD/SCID mice

M. Fischer, J. Lewicki, A. Gurney, 2011 .

Epistatic interaction between haplotypes of the ghrelin ligand and receptor genes influence susceptibility to myocardial infarction and coronary artery disease.

S. Wiedmann, J. Erdmann, C. Hengstenberg, 2007, Human molecular genetics.

Lymphotoxin-α and galectin-2 SNPs are not associated with myocardial infarction in two different German populations

J. Erdmann, C. Hengstenberg, T. Meitinger, 2007, Journal of Molecular Medicine.

Signal transducer of inflammation gp130 modulates atherosclerosis in mice and man

C. Trautwein, C. Hengstenberg, M. Fischer, 2007, The Journal of experimental medicine.

ISAR-SAFE: a randomized, double-blind, placebo-controlled trial of 6 vs. 12 months of clopidogrel therapy after drug-eluting stenting.

Walter Desmet, Karl-Ludwig Laugwitz, Yi Li, 2015, European heart journal.

Prevalence of left ventricular diastolic dysfunction in the community. Results from a Doppler echocardiographic-based survey of a population sample.

H. Hense, C. Hengstenberg, M. Fischer, 2003, European heart journal.

Association between a polymorphism in the G protein beta3 subunit gene (GNB3) with arterial hypertension but not with myocardial infarction.

C. Hengstenberg, M. Fischer, H. Schunkert, 2001, Cardiovascular research.

Percentiles for left ventricular rotation: comparison of reference values to paediatric patients with pacemaker-induced dyssynchrony.

M. Fischer, H. Körperich, L. Faber, 2014, European heart journal cardiovascular Imaging.

Model versus non-model based left ventricular volumetry - A matter of imaging modality or quantification software?

Gregory C. Dachner, M. Fischer, W. Burchert, 2013 .

Prediction of mortality in adult patients with severe acute lung failure receiving veno-venous extracorporeal membrane oxygenation: a prospective observational study

M. Fischer, V. Videm, T. Bein, 2014, Critical Care.

Association of the Ghrelin Receptor Gene Region With Left Ventricular Hypertrophy in the General Population: Results of the MONICA/KORA Augsburg Echocardiographic Substudy

J. Erdmann, C. Hengstenberg, M. Fischer, 2006, Hypertension.

[Epidemiology of left ventricular systolic dysfunction in the general population of Germany: results of an echocardiographic study of a large population-based sample].

M. Fischer, A. Baessler, H. Schunkert, 2003, Zeitschrift für Kardiologie.

Familial aggregation of left main coronary artery disease and future risk of coronary events in asymptomatic siblings of affected patients.

J. Erdmann, C. Hengstenberg, Bjoern Mayer, 2007, European heart journal.

Renin angiotensin system and gender differences in the cardiovascular system.

M. Fischer, A. Baessler, H. Schunkert, 2002, Cardiovascular research.

Association between Single Nucleotide Polymorphisms and Weight Reduction in Behavioural Interventions—A Pooled Analysis

M. Fischer, A. Baessler, T. Illig, 2021, Nutrients.

Successful weight reduction improves left ventricular diastolic function and physical performance in severe obesity.

M. Fischer, A. Baessler, G. Schmitz, 2015, International heart journal.

Adiponectin multimeric forms but not total adiponectin levels are associated with myocardial infarction in non-diabetic men.

C. Hengstenberg, M. Fischer, A. Baessler, 2011, Journal of atherosclerosis and thrombosis.

Gender differences in cardiometabolic health and disease in a cross-sectional observational obesity study

M. Fischer, A. Baessler, G. Behrens, 2022, Biology of sex differences.

Successful weight loss reduces endothelial activation in individuals with severe obesity participating in a multimodal weight loss program.

M. Fischer, A. Baessler, L. Maier, 2021, Obesity research & clinical practice.

Relation Between Obesity, Metabolic Syndrome, Successful Long-Term Weight Reduction, and Right Ventricular Function.

M. Fischer, A. Baessler, L. Maier, 2016, International heart journal.

Therapeutic Targeting of Tumor-Derived R-Spondin Attenuates β-Catenin Signaling and Tumorigenesis in Multiple Cancer Types.

M. Fischer, J. Lewicki, A. Gurney, 2016, Cancer research.

The common Y402H variant in complement factor H gene is not associated with susceptibility to myocardial infarction and its related risk factors.

S. Wiedmann, J. Erdmann, C. Hengstenberg, 2007, Clinical science.

The common Y 402 H variant in complement factor H gene is not associated with susceptibility to myocardial infarction and its related risk factors

S. Wiedmann, J. Erdmann, C. Hengstenberg, 2007 .

The adipo‐fibrokine activin A is associated with metabolic abnormalities and left ventricular diastolic dysfunction in obese patients

M. Fischer, A. Baessler, L. Maier, 2019, ESC heart failure.

Abstract 1943: PARG inhibitors exhibit synthetic lethality with XRCC1 deficiency and a cellular mechanism of action that is distinct from PARP inhibition

Kedar S Vaidya, M. P. Dillon, M. Fischer, 2018, Experimental and Molecular Therapeutics.

Cancer Therapy : Preclinical Anti-DLL 4 HasBroad SpectrumActivity in Pancreatic Cancer DependentonTargetingDLL 4-NotchSignaling inBothTumor and Vasculature Cells

Edward J. Kim, M. Fischer, J. Lewicki, 2012 .

Adipocyte fatty acid-binding protein levels are associated with left ventricular diastolic dysfunction in morbidly obese subjects

M. Fischer, A. Baessler, S. Bornstein, 2014, Nutrition & Diabetes.

Generation of Highly Purified Human Cardiomyocytes from Peripheral Blood Mononuclear Cell-Derived Induced Pluripotent Stem Cells

C. Hengstenberg, M. Fischer, A. Baessler, 2015, PloS one.

Association of the metabolic syndrome with early coronary disease in families with frequent myocardial infarction.

C. Hengstenberg, Bjoern Mayer, M. Fischer, 2006, The American journal of cardiology.

The role of the tubular biomarkers NAG, kidney injury molecule-1 and neutrophil gelatinase-associated lipocalin in patients with chest pain before contrast media exposition.

M. Fischer, L. Maier, A. Luchner, 2019, Biomarkers in medicine.

Association between PPARalpha gene polymorphisms and myocardial infarction.

S. Wiedmann, J. Erdmann, C. Hengstenberg, 2008, Clinical science.

Abstract C164: Dual targeting of the DLL4 and VEGF pathways with a bispecific monoclonal antibody inhibits tumor growth and reduces cancer stem cell frequency

M. Fischer, J. Lewicki, A. Gurney, 2015 .

Genetic variation in the arachidonate 5-lipoxygenase-activating protein (ALOX5AP) is associated with myocardial infarction in the German population.

I. König, A. Ziegler, J. Erdmann, 2008, Clinical science.

Lack of Association Between the MEF2A Gene and Myocardial Infarction

I. König, A. Ziegler, J. Erdmann, 2008, Circulation.

Abstract 3129: Predictive biomarker identification for response to vantictumab (OMP-18R5; anti-Frizzled) using primary patient-derived human pancreatic tumor xenografts

M. Fischer, J. Lewicki, A. Gurney, 2016 .

Association between arterial pressure and coronary artery calcification

H. Hense, J. Erdmann, C. Hengstenberg, 2007, Journal of hypertension.

The ECMOnet score: a useful tool not to be taken absolutely

M. Fischer, T. Bein, J. Langgartner, 2013, Intensive Care Medicine.

Abstract 404: Development of a RSPO3 CLIA-validated assay as a predictive biomarker for response to anti-RSPO3 antibody treatment in patients with solid tumors

M. Fischer, J. Lewicki, A. Gurney, 2016 .

SNP dependent modulation of circulating miRNAs from the miR25/93/106 cluster in patients undergoing weight loss.

M. Fischer, A. Baessler, G. Schmitz, 2020, Gene.

Repeated Replication and a Prospective Meta-Analysis of the Association Between Chromosome 9p21.3 and Coronary Artery Disease

P. Deloukas, I. König, L. Hothorn, 2008, Circulation.

Old and simple tools may do better--sometimes.

M. Fischer, H. Schunkert, 2002, European heart journal.

Failure to achieve recommended LDL cholesterol levels by suboptimal statin therapy relates to elevated cardiac event rates.

C. Hengstenberg, M. Fischer, A. Baessler, 2005, International journal of cardiology.

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

Joshua M. Korn, Benjamin J. Wright, P. Deloukas, 2009, Nature Genetics.

Anti-DLL4 inhibits growth and reduces tumor-initiating cell frequency in colorectal tumors with oncogenic KRAS mutations.

M. Fischer, J. Lewicki, A. Gurney, 2011, Cancer research.

Dysfunctional nitric oxide signalling increases risk of myocardial infarction

M. Nöthen, J. Ott, N. Samani, 2013, Nature.

Targeting Notch Signaling with a Notch2/Notch3 Antagonist (Tarextumab) Inhibits Tumor Growth and Decreases Tumor-Initiating Cell Frequency

M. Fischer, J. Lewicki, A. Gurney, 2015, Clinical Cancer Research.

Validation of the DAPT score in patients randomized to 6 or 12 months clopidogrel after predominantly second-generation drug-eluting stents

M. Fischer, H. Schunkert, A. Kastrati, 2017, Thrombosis and Haemostasis.

Phase 1b of WNT inhibitor ipafricept (IPA, decoy receptor for WNT ligands) with carboplatin (C) and paclitaxel (P) in recurrent platinum-sensitive ovarian cancer (OC).

M. Fischer, P. Sabbatini, F. Cattaruzza, 2016 .