B. Seetharam

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Receptor-mediated endocytosis of cobalamin (vitamin B12).

B. Seetharam, 1999, Annual review of nutrition.

Sterol carrier protein hypothesis: requirement for three substrate-specific soluble proteins in liver cholesterol biosynthesis.

B. Seetharam, M. K. Lewis, M. V. Srikantaiah, 1975, Life sciences.

Basolateral sorting signal of the 300-kDa mannose 6-phosphate receptor.

B. Seetharam, N. Dahms, D. A. Wick, 2002, American journal of physiology. Gastrointestinal and liver physiology.

Expression of cobalamin transport proteins and cobalamin transcytosis by colon adenocarcinoma cells.

B. Seetharam, K. Ramanujam, S. Seetharam, 1991, The American journal of physiology.

Bipolar Functional Expression of Transcobalamin II Receptor in Human Intestinal Epithelial Caco-2 Cells*

B. Seetharam, N. Dahms, S. Seetharam, 1997, The Journal of Biological Chemistry.

Expression of IGF-II and IGF binding proteins in differentiating human intestinal Caco-2 cells.

B. Seetharam, N. Dahms, D. A. Wick, 1995, The American journal of physiology.

Polymorphism of human transcobalamin II: substitution of proline and/or glutamine residues by arginine.

B. Seetharam, G. Sood, S. Seetharam, 1994, Biochimica et biophysica acta.

Chapter 2 Intestinal absorption of water-soluble vitamins: Cellular and molecular aspects

B. Seetharam, R. C. Rose, H. Said, 2000 .

Characterization of mannose 6-phosphate receptors (MPRs) from opossum liver: opossum cation-independent MPR binds insulin-like growth factor-II.

B. Seetharam, N. Dahms, K. Ramanujam, 1993, Endocrinology.

Biosynthesis and secretion of the mannose 6-phosphate receptor and its ligands in polarized Caco-2 cells.

B. Seetharam, N. Dahms, D. A. Wick, 1999, American journal of physiology. Gastrointestinal and liver physiology.

Biosynthesis and secretion of the mannose 6-phosphate receptor and its ligands in polarized Caco-2 cells.

B. Seetharam, N. Dahms, D. A. Wick, 1999, The American journal of physiology.

Transcobalamin II Receptor Interacts with Megalin in the Renal Apical Brush Border Membrane

B. Seetharam, N. Dahms, S. Seetharam, 2003, The Journal of Membrane Biology.

How does cobalamin (vitamin B12) enter and traverse mammalian cells?

B. Seetharam, 1987, Journal of Biosciences.

Hydrophobic interactions of brush border alkaline phosphatases: the role of phosphatidyl inositol.

B. Seetharam, C. Tiruppathì, D. Alpers, 1987, Archives of biochemistry and biophysics.

Immunohistochemical survey of cobalamin-binding proteins.

B. Seetharam, D. Alpers, K. Deschryver‐Kecskemeti, 1989, Gastroenterology.

Phase separation of rat intestinal brush border membrane proteins using Triton X-114.

B. Seetharam, C. Tiruppathì, D. Alpers, 1986, Analytical biochemistry.

Intrinsic factor receptor activity and cobalamin transport in bile duct-ligated rats.

B. Seetharam, K. Ramanujam, S. Seetharam, 1992, The American journal of physiology.

Identification of two mutant alleles of transcobalamin II in an affected family.

B. Seetharam, D. Rosenblatt, B. Kamen, 1994, Human molecular genetics.

Cobalamin (vitamin B12) binding, phylogeny, and synteny of human transcobalamin.

B. Seetharam, S. Kalra, Ning Li, 2004, Archives of biochemistry and biophysics.

Transcobalamin II and its cell surface receptor.

B. Seetharam, N. Li, 2000, Vitamins and hormones.

Effect of exocrine pancreatic insufficiency on small intestine in the mouse

B. Seetharam, D. Alpers, W. Kwong, 1978 .

Effects of interferon beta on transcobalamin II-receptor expression and antitumor activity of nitrosylcobalamin.

B. Seetharam, J. Drazba, B. Jacobs, 2002, Journal of the National Cancer Institute.

Cellular import of cobalamin (Vitamin B-12).

B. Seetharam, N. Li, B Seetharam, 1999, The Journal of nutrition.

Effect of proteolytic enzymes on the binding of cobalamin to R protein and intrinsic factor. In vitro evidence that a failure to partially degrade R protein is responsible for cobalamin malabsorption in pancreatic insufficiency.

B. Seetharam, E. Podell, D. Alpers, 1978, The Journal of clinical investigation.

Gastric Intrinsic Factor and Cobalamin Absorption

B. Seetharam, D. Alpers, 2011 .

Disruption of a Regulatory System Involving Cobalamin Distribution and Function in a Methionine-dependent Human Glioma Cell Line*

B. Seetharam, R. Banerjee, P. Ueland, 1998, The Journal of Biological Chemistry.

Isolation and sequence analysis of variant forms of human transcobalamin II.

B. Seetharam, J. Lindemans, F. Arwert, 1993, Biochimica et biophysica acta.

Rat transcobalamin: cloning and regulation of mRNA expression

B. Seetharam, S. Kalra, S. Seetharam, 2004, The Journal of physiology.

Membrane Expression and Interactions of Human Transcobalamin II Receptor (*)

B. Seetharam, S. Seetharam, S. Bose, 1995, The Journal of Biological Chemistry.

Synthesis and secretion of cobalamin binding proteins by opossum kidney cells.

B. Seetharam, K. Ramanujam, S. Seetharam, 1991, Biochemical and biophysical research communications.

Renal brush border membrane bound intrinsic factor.

B. Seetharam, K. Ramanujam, S. Seetharam, 1990, Biochimica et biophysica acta.

Cellular uptake of cobalamin.

B. Seetharam, D. Alpers, 2009, Nutrition reviews.

Isolation and characterization of a cDNA encoding porcine gastric haptocorrin.

B. Seetharam, J. Leykam, D. Alpers, 1990, European journal of biochemistry.

Absorption and transport of cobalamin (vitamin B12).

B. Seetharam, D. Alpers, 1982, Annual review of nutrition.

Studies on mammalian glucoamylases with special reference to monkey intestinal glucoamylase.

B. Seetharam, A. N. Radhakrishnan, N. Swaminathan, 1970, Biochemical Journal.

Characterization and comparison of soluble and membranous forms of intestinal alkaline phosphatase from the suckling rat.

B. Seetharam, G. Young, D. Alpers, 1981, The Journal of biological chemistry.

Regulated expression of intrinsic factor-cobalamin receptor by rat visceral yolk sac and placental membranes.

B. Seetharam, K. Ramanujam, S. Seetharam, 1993, Biochimica et biophysica acta.

Membrane interactions of rat intestinal alkaline phosphatase: role of polar head groups.

B. Seetharam, C. Tiruppathì, D. Alpers, 1985, Biochemistry.

Development of intestinal brush border membrane proteins in the rat.

B. Seetharam, D. Alpers, K. Yeh, 1977, Biochimica et biophysica acta.

Effects of dietary fish oil supplementation on membrane fluidity and enzyme activity in rat small intestine.

B. Seetharam, W. Pickett, P. Dudeja, 1989, The Biochemical journal.

The role of choline on the activity-temperature relationship of brush-border alkaline phosphatase.

B. Seetharam, C. Tiruppathì, D. Alpers, 1987, Biochimica et biophysica acta.

A 69-Base Pair Fragment Derived from Human Transcobalamin II Promoter Is Sufficient for High Bidirectional Activity in the Absence of a TATA Box and an Initiator Element in Transfected Cells

B. Seetharam, Ning Li, 1998, The Journal of Biological Chemistry.

Characterization of the Human Transcobalamin II Promoter

B. Seetharam, Ning Li, S. Seetharam, 1998, The Journal of Biological Chemistry.

Identification of rat yolk sac target protein of teratogenic antibodies, gp280, as intrinsic factor-cobalamin receptor.

T. Hammond, B. Seetharam, S. Moestrup, 1997, The Journal of clinical investigation.

Cobalamin transport proteins and their cell-surface receptors

B. Seetharam, R. Yammani, 2003, Expert Reviews in Molecular Medicine.

Loss of albumin and megalin binding to renal cubilin in rats results in albuminuria after total body irradiation.

B. Seetharam, Mukut Sharma, J. Moulder, 2002, American journal of physiology. Regulatory, integrative and comparative physiology.

Overexpression of an unstable intrinsic factor-cobalamin receptor in Imerslund-Gräsbeck syndrome.

B. Seetharam, J. Livingston, J. Puntis, 1998, Gastroenterology.

Differential sensitivity of intestinal brush border enzymes to pancreatic and lysosomal proteases.

B. Seetharam, D. Alpers, C. Goodwin, 1976, Life sciences.

Terminal Ileum Resection Is Associated With Higher Plasma Homocysteine Levels in Crohn's Disease

B. Seetharam, D. Binion, M. Abu-Hajir, 2001, Journal of clinical gastroenterology.

Pathophysiology of diseases involving intestinal brush-border proteins.

B. Seetharam, D. Alpers, 1977, The New England journal of medicine.

Immunocytochemical localization of the intrinsic factor-cobalamin receptor in dog-ileum: distribution of intracellular receptor during cell maturation

B. Seetharam, J. Levine, D. Alpers, 1984, The Journal of cell biology.

Functional expression of transcoabalamin II cDNA In Xenopuslaevis oocytes

B. Seetharam, N. Dahms, Ning Li, 1991 .

Plasma membrane delivery, endocytosis and turnover of transcobalamin receptor in polarized human intestinal epithelial cells

B. Seetharam, S. Kalra, S. Bose, 2007, The Journal of physiology.

Human transcobalamin II receptor binds to Staphylococcus aureus protein A: implications as to its structure and function.

B. Seetharam, S. Seetharam, Sravan K. Vanamala, 2003, Archives of biochemistry and biophysics.

Normal and abnormal physiology of intrinsic factor mediated absorption of cobalamin (vitamin B12).

J. Fyfe, B. Seetharam, K. Ramanujam, 1991, Indian Journal of Biochemistry & Biophysics.

Defective brush-border expression of intrinsic factor-cobalamin receptor in canine inherited intestinal cobalamin malabsorption.

J. Fyfe, B. Seetharam, K. Ramaswamy, 1991, The Journal of biological chemistry.

Purification, properties, and immunochemical localization of a receptor for intrinsic factor-cobalamin complex in the rat kidney.

B. Seetharam, J. Levine, D. Alpers, 1988, The Journal of biological chemistry.

Isolation and characterization of the ileal receptor for intrinsic factor-cobalamin.

B. Seetharam, D. Alpers, D. Alpers, 1981, The Journal of biological chemistry.

Synthesis and brush border expression of intrinsic factor-cobalamin receptor from rat renal cortex.

B. Seetharam, K. Ramanujam, S. Seetharam, 1992, The Journal of biological chemistry.

Isolation and characterization of proteolytically derived ileal receptor for intrinsic factor-cobalamin.

B. Seetharam, D. Alpers, S. Bagur, 1982, The Journal of biological chemistry.

Binding of intrinsic factor to ileal brush border membrane in the rat.

B. Seetharam, J. Bakke, D. Alpers, 1983, Biochemical and biophysical research communications.

Cubilin and megalin expression and their interaction in the rat intestine: effect of thyroidectomy.

B. Seetharam, R. Yammani, S. Seetharam, 2001, American journal of physiology. Endocrinology and metabolism.

Interaction of Intestinal Disaccharidases with Phospholipids: Effect of Cholesterol

B. Seetharam, C. Tiruppathì, D. Alpers, 1985, Journal of pediatric gastroenterology and nutrition.

Expression of insulin-like growth factor (IGF)-I receptors, IGF-II/cation-independent mannose 6-phosphate receptors (CI-MPRs), and cation-dependent MPRs in polarized human intestinal Caco-2 cells.

B. Seetharam, N. Dahms, D. A. Wick, 1996, Biochimica et biophysica acta.

Genomic structure of human transcobalamin II: comparison to human intrinsic factor and transcobalamin I.

B. Seetharam, S. Seetharam, N. Li, 1995, Biochemical and biophysical research communications.

Brefeldin A (BFA) Inhibits Basolateral Membrane (BLM) Delivery and Dimerization of Transcobalamin II Receptor in Human Intestinal Epithelial Caco-2 Cells

B. Seetharam, J. Feix, S. Chapin, 1998, The Journal of Biological Chemistry.

Effect of pancreatic proteases on intestinal lactase activity.

B. Seetharam, D. Alpers, R. Perrillo, 1980, Gastroenterology.

Nonsense mutations in human transcobalamin II deficiency.

B. Seetharam, D. Rosenblatt, N. Li, 1994, Biochemical and biophysical research communications.

Identification and Characterization of Two Distinct Ligand Binding Regions of Cubilin*

B. Seetharam, S. Seetharam, R. Yammani, 2001, The Journal of Biological Chemistry.

Cobalamin-mediated regulation of transcobalamin receptor levels in rat organs.

B. Seetharam, D. Veber, S. Kalra, 2007, Archives of biochemistry and biophysics.

Dimerization of Transcobalamin II Receptor

B. Seetharam, J. Feix, S. Seetharam, 1996, The Journal of Biological Chemistry.

Regulation of lysosomal and ubiquitin degradative pathways in differentiating human intestinal Caco-2 cells.

B. Seetharam, N. Dahms, D. A. Wick, 1995, Biochimica et biophysica acta.

Intrinsic factor-cobalamin receptor activity in a marsupial, the American opossum (Didelphis virginiana).

B. Seetharam, K. Ramanujam, S. Seetharam, 1993, Comparative biochemistry and physiology. Comparative physiology.

Isolation of native and proteolytically derived ileal receptor for intrinsic factor-cobalamin.

B. Seetharam, D. Alpers, 1986, Methods in Enzymology.

Functional expression of intrinsic factor-cobalamin receptor by renal proximal tubular epithelial cells.

B. Seetharam, N. Dahms, K. Ramanujam, 1991, The Journal of biological chemistry.

Effect of bile and bile acids on binding of intrinsic factor to cobalamin and intrinsic factor-cobalamin complex to ileal receptor.

B. Seetharam, D. Alpers, M. Jimenez, 1983, The American journal of physiology.

Isolation and structural characterization of a cDNA clone encoding rat gastric intrinsic factor.

B. Seetharam, J. Leykam, B. Dieckgraefe, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Interaction of receptor for intrinsic factor-cobalamin complex with synthetic and brush-border lipids.

B. Seetharam, D. Alpers, S. Bagur, 1981, The Journal of biological chemistry.

Function and stability of human transcobalamin II: role of intramolecular disulfide bonds C98-C291 and C147-C187.

B. Seetharam, D. Alpers, S. Kalra, 2003, American journal of physiology. Cell physiology.

Effect of Disulfide Bonds of Transcobalamin II Receptor on Its Activity and Basolateral Targeting in Human Intestinal Epithelial Caco-2 Cells*

B. Seetharam, S. Bose, 1997, The Journal of Biological Chemistry.

In Vitro and in Vivo Inactivation of Transcobalamin II Receptor by Its Antiserum (*)

B. Seetharam, D. Rosenblatt, R. Komorowski, 1996, The Journal of Biological Chemistry.

The Intrinsic Factor‐Cobalamin Receptor Expressed by Yolk Sac and Proximal Tubule Epithelial Cells is the Target of Teratogenic Antibodies

B. Seetharam, S. Moestrup, P. Verroust, 2007 .

Characterization of mannose 6-phosphate receptors (MPRs) from opossum liver: opossum cation-independent MPR binds insulin-like growth factor-II.

B. Seetharam, N. Dahms, K. Ramanujam, 1993, Endocrinology.

Interactions of cubilin with megalin and the product of the amnionless gene (AMN): effect on its stability.

B. Seetharam, S. Kalra, J. A. Bauer, 2008, The Biochemical journal.

Developmental regulation of rat intrinsic factor mRNA.

B. Seetharam, B. Dieckgraefe, D. Alpers, 1988, The American journal of physiology.

Cobalamin release from intrinsic factor and transfer to transcobalamin II within the rat enterocyte.

B. Seetharam, D. Alpers, M. Ramasamy, 1989, The American journal of physiology.

Intestinal -glycosidases: -mannosidase & -galactosidase from monkey small intestine.

B. Seetharam, A. N. Radhakrishnan, 1972, Indian journal of biochemistry & biophysics.