D. Connolly

发表

Molecular docking and high-throughput screening for novel inhibitors of protein tyrosine phosphatase-1B.

B. Shoichet, T. Doman, S. McGovern, 2002, Journal of medicinal chemistry.

Characterization of vascular permeability factor/vascular endothelial growth factor receptors on mononuclear phagocytes.

D. Connolly, A. Schmidt, D. Stern, 1993, Blood.

Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis.

D. Connolly, J. Feder, B. Eppley, 1989, The Journal of clinical investigation.

(d)-β-Hydroxybutyrate Inhibits Adipocyte Lipolysis via the Nicotinic Acid Receptor PUMA-G*

D. Connolly, S. Offermanns, S. Wright, 2005, Journal of Biological Chemistry.

Langerhans cells release prostaglandin D2 in response to nicotinic acid.

D. Connolly, Y. Hakak, I. Gaidarov, 2006, The Journal of investigative dermatology.

3-Nitro-4-amino benzoic acids and 6-amino nicotinic acids are highly selective agonists of GPR109b.

D. Connolly, S. Tamura, C. Sage, 2007, Bioorganic & medicinal chemistry letters.

Fluorinated pyrazole acids are agonists of the high affinity niacin receptor GPR109a.

D. Connolly, S. Tamura, Vu P Hong, 2007, Bioorganic & medicinal chemistry letters.

Analogues of acifran: agonists of the high and low affinity niacin receptors, GPR109a and GPR109b.

D. Connolly, C. Sage, Jae-Kyu Jung, 2007, Journal of medicinal chemistry.

Agonist lead identification for the high affinity niacin receptor GPR109a.

Brian M. Smith, D. Connolly, S. Tamura, 2007, Bioorganic & medicinal chemistry letters.

Nicotinic Acid Receptor Agonists Differentially Activate Downstream Effectors*

D. Connolly, S. Wright, Douglas P. Boatman, 2007, Journal of Biological Chemistry.

3-(1H-tetrazol-5-yl)-1,4,5,6-tetrahydro-cyclopentapyrazole (MK-0354): a partial agonist of the nicotinic acid receptor, G-protein coupled receptor 109a, with antilipolytic but no vasodilatory activity in mice.

D. Connolly, S. Tamura, C. Sage, 2008, Journal of medicinal chemistry.

Effects of a niacin receptor partial agonist, MK-0354, on plasma free fatty acids, lipids, and cutaneous flushing in humans.

D. Connolly, J. Paolini, J. Wagner, 2008, Journal of clinical lipidology.

5-N,N-Disubstituted 5-aminopyrazole-3-carboxylic acids are highly potent agonists of GPR109b.

D. Connolly, S. Tamura, C. Sage, 2009, Bioorganic & medicinal chemistry letters.

Human vascular permeability factor. Isolation from U937 cells.

D. Connolly, J. Feder, R. Leimgruber, 1989, The Journal of biological chemistry.

(1aR,5aR)1a,3,5,5a-Tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalene-4-carboxylic acid (MK-1903): a potent GPR109a agonist that lowers free fatty acids in humans.

D. Connolly, J. Knudsen, C. Sage, 2012, Journal of medicinal chemistry.

Regulation of hexose transport in aortic endothelial cells by vascular permeability factor and tumor necrosis factor-alpha, but not by insulin.

D. Connolly, P. Pekala, D. Heuvelman, 1990, The Journal of biological chemistry.

Characterization of the increase in vascular permeability induced by vascular permeability factor in vivo

D. Connolly, P. Collins, T. Williams, 1993, British journal of pharmacology.

Determination of the number of endothelial cells in culture using an acid phosphatase assay.

D. Connolly, M. B. Knight, J. Feder, 1986, Analytical biochemistry.

Novel heteroaryl replacements of aromatic 3-tetrafluoroethoxy substituents in trifluoro-3-(tertiaryamino)-2-propanols as potent inhibitors of cholesteryl ester transfer protein.

B. Witherbee, D. Connolly, R. C. Durley, 2001, Bioorganic & medicinal chemistry letters.

Physical and kinetic characterization of recombinant human cholesteryl ester transfer protein.

D. Connolly, K. Glenn, E. Krul, 1996, The Biochemical journal.

Inhibition of Mas G-protein signaling improves coronary blood flow, reduces myocardial infarct size, and provides long-term cardioprotection.

John W. Adams, D. Connolly, Zhuangjie Li, 2012, American journal of physiology. Heart and circulatory physiology.

Large-scale purification of myeloperoxidase from HL60 promyelocytic cells: characterization and comparison to human neutrophil myeloperoxidase.

D. Connolly, M. C. Walker, D. Heuvelman, 2000, Protein expression and purification.

Niacin Lipid Efficacy Is Independent of Both the Niacin Receptor GPR109A and Free Fatty Acid Suppression

D. Rader, D. Connolly, Jiajun Liu, 2012, Science Translational Medicine.

Enhancement of angiogenesis by bFGF in mandibular bone graft healing in the rabbit.

D. Connolly, J. Feder, B. Eppley, 1988, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

Vascular permeability factor: A unique regulator of blood vessel function

D. Connolly, 1991, Journal of cellular biochemistry.

Regulation of Vascular Function by Vascular Permeability Factor

D. Connolly, 1991 .

Specific binding of vascular permeability factor to endothelial cells.

D. Connolly, J. Olander, J. Delarco, 1991, Biochemical and biophysical research communications.

Inhibition of cholesteryl ester transfer protein by apolipoproteins, lipopolysaccharides, and cholesteryl sulfate.

D. Connolly, K. Glenn, E. Krul, 1996, Biochimica et biophysica acta.

Inhibition of cholesteryl ester transfer protein by substituted dithiobisnicotinic acid dimethyl ester: involvement Of a critical cysteine.

B. Witherbee, D. Connolly, A. Tall, 2000, Journal of lipid research.

Human fibroblast-derived growth factor is a mitogen and chemoattractant for endothelial cells.

B. Stoddard, D. Connolly, J. Feder, 1987, Biochemical and biophysical research communications.

Binding and endocytosis of cluster glycosides by rabbit hepatocytes. Evidence for a short-circuit pathway that does not lead to degradation.

D. Connolly, R. Townsend, W. Bell, 1982, The Journal of biological chemistry.

Large‐Scale Purification of Tissue‐Type Plasminogen Activator from Cultured Human Cells

D. Connolly, J. Feder, A. Wittwer, 1988 .

The role of the GPR91 ligand succinate in hematopoiesis

D. Connolly, Y. Hakak, C. Liaw, 2009, Journal of leukocyte biology.

Vascular endothelial growth factor as capillary permeability agent in ovarian hyperstimulation syndrome

D. Connolly, P. Rogers, N. Mcclure, 1994, The Lancet.

Sequence polymorphisms provide a common consensus sequence for GPR41 and GPR42.

D. Connolly, C. Liaw, 2009, DNA and cell biology.

1-Alkyl-benzotriazole-5-carboxylic acids are highly selective agonists of the human orphan G-protein-coupled receptor GPR109b.

D. Connolly, S. Tamura, C. Sage, 2006, Journal of medicinal chemistry.

APD791, 3-Methoxy-N-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide, a Novel 5-Hydroxytryptamine 2A Receptor Antagonist: Pharmacological Profile, Pharmacokinetics, Platelet Activity and Vascular Biology

John W. Adams, D. Connolly, Michael E. Morgan, 2009, Journal of Pharmacology and Experimental Therapeutics.

Anti-thrombotic and vascular effects of AR246686, a novel 5-HT2A receptor antagonist.

John W. Adams, D. Connolly, P. Dosa, 2008, European journal of pharmacology.

Steady state and kinetic analysis of the binding of asialoorosomucoid to the isolated rabbit hepatic lectin.

D. Connolly, M. K. Hobish, Y. Lee, 1981, The Journal of biological chemistry.

Preparation of anomeric pairs of 1-thioglycosides: use of anomerization catalyzed by boron trifluoride

D. Connolly, S. Roseman, Yuan-chuan Lee, 1980 .

Stereospecific inhibition of CETP by chiral N,N-disubstituted trifluoro-3-amino-2-propanols.

B. Witherbee, D. Connolly, R. C. Durley, 2000, Biochemistry.

Identification, Purification, and Characterization of Cell-surface Retention Sequence-binding Proteins from Human SK-Hep Cells and Bovine Liver Plasma Membranes (*)

D. Connolly, S. S. Huang, J. Huang, 1995, The Journal of Biological Chemistry.

morpholinoethoxy ) phenyl ) benzamide ( APD 791 ) : AHighly Selective 5-Hydroxytryptamine 2 A Receptor Inverse Agonist for the Treatment of Arterial Thrombosis

John W. Adams, D. Connolly, P. Dosa, 2010 .

Chiral N,N-disubstituted trifluoro-3-amino-2-propanols are potent inhibitors of cholesteryl ester transfer protein.

B. Witherbee, D. Connolly, K. Glenn, 2002, Journal of medicinal chemistry.

Discovery of chiral N,N-disubstituted trifluoro-3-amino-2-propanols as potent inhibitors of cholesteryl ester transfer protein.

B. Witherbee, D. Connolly, K. Glenn, 2000, Journal of medicinal chemistry.

Myocardial expression, signaling, and function of GPR22: a protective role for an orphan G protein-coupled receptor.

John Ross, John W. Adams, J. Ross, 2008, American journal of physiology. Heart and circulatory physiology.

Human mesangial cells and peripheral blood mononuclear cells produce vascular permeability factor.

D. Connolly, N. Yoshikawa, K. Iijima, 1993, Kidney international.

Cell density-dependent stimulation of glutamine synthetase activity in cultured mouse teratoma cells.

D. Connolly, S. Oppenheimer, 1975, Experimental cell research.

Vascular permeability factor, an endothelial cell mitogen related to PDGF.

D. Connolly, S. Hauser, J. Feder, 1989, Science.

Binding and endocytosis of glycoproteins and neoglycoproteins by isolated rabbit hepatocytes.

D. Connolly, R. Townsend, M. K. Hobish, 1983, The Biochemical journal.

Purification and NH2-terminal amino acid sequence of guinea pig tumor-secreted vascular permeability factor.

D. Connolly, H. Dvorak, J. Feder, 1990, Cancer research.

Vascular permeability factor: a tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration

D. Connolly, P. Familletti, H. Gerlach, 1990, The Journal of experimental medicine.

Vascular permeability factor accelerates endothelial regrowth following balloon angioplasty.

D. Connolly, A. Callow, S. Stevens, 1994, Growth factors.

Effects of a variety of cytokines and inducing agents on vascular permeability factor mRNA levels in U937 cells.

D. Connolly, G. Dolecki, 1991, Biochemical and biophysical research communications.

Cell Surface Retention Sequence Binding Protein-1 Interacts with the v-sis Gene Product and Platelet-derived Growth Factor β-Type Receptor in Simian Sarcoma Virus-transformed Cells*

D. Connolly, J. Huang, S. Huang, 1999, The Journal of Biological Chemistry.

Synthesis, turnover, and down-regulation of epidermal growth factor receptors in human A431 epidermoid carcinoma cells and skin fibroblasts.

D. Connolly, M. Lane, M. Krupp, 1982, The Journal of biological chemistry.

Free Bone Graft Reconstruction of Irradiated Facial Tissue: Experimental Effects of Basic Fibroblast Growth Factor Stimulation

D. Connolly, B. Eppley, A. Sadove, 1991, Plastic and reconstructive surgery.

Inactivation of cholesteryl ester transfer protein by cysteine modification.

D. Connolly, K. Glenn, D. Heuvelman, 1996, Biochemical and biophysical research communications.

Molecular Docking and High-Throughput Screening for Novel Inhibitors of Protein Tyrosine Phosphatase-1 B

Brian K. Shoichet, Thompson N. Doman, Daniel T. Connolly, 2022 .