K. Wilson

发表

Chemogenomic approaches to drug discovery.

M. Murcko, P. Caron, M. D. Mullican, 2001, Current opinion in chemical biology.

The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase.

G. Bemis, M. Murcko, P. Caron, 1997, Chemistry & biology.

Escherichia coli biotin holoenzyme synthetase/bio repressor crystal structure delineates the biotin- and DNA-binding domains.

B. Matthews, K. Wilson, L. Shewchuk, 1992, Proceedings of the National Academy of Sciences of the United States of America.

The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivity.

K. Wilson, P. Charifson, L. Swenson, 2000, Chemistry & biology.

The genesis of high-throughput structure-based drug discovery using protein crystallography.

Peter Kuhn, Raymond C Stevens, R. Stevens, 2002, Current opinion in chemical biology.

Structural and thermodynamic analysis of compensating mutations within the core of chicken egg white lysozyme.

B. Matthews, K. Wilson, B. Malcolm, 1993, The Journal of biological chemistry.

Enhancement of protein stability by the combination of point mutations in T4 lysozyme is additive.

B K Shoichet, B. Matthews, B. Shoichet, 1995, Protein engineering.

Structure and mechanism of interleukin-lβ converting enzyme

Mark A. Murcko, David J. Livingston, M. Murcko, 1994, Nature.

Structure-based design of non-peptidic pyridone aldehydes as inhibitors of interleukin-1β converting enzyme

G. Bemis, M. D. Mullican, K. Wilson, 1997 .

Structure and mechanism of interleukin-1 beta converting enzyme.

M. Murcko, K. Wilson, M. Navia, 1994, Nature.

Insights into selectivity of STI571 [GleevecTM] from X-ray crystallography

K. Wilson, D. McRee, Devon A. Thompson, 2003 .

Time-resolved X-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis

Steven C. Almo, Ilme Schlichting, Alfred Wittinghofer, 1990, Nature.

Inhibitors of hepatitis C virus NS3.4A protease. Part 3: P2 proline variants.

M. Murcko, K. Wilson, B. G. Rao, 2004, Bioorganic & medicinal chemistry letters.

Structure of catalase HPII from Escherichia coli at 1.9 Å resolution

K. Wilson, J. Bravo, K. Wilson, 1999, Proteins.

Structure and Mechanism of Inosine Monophosphate Dehydrogenase in Complex with the Immunosuppressant Mycophenolic Acid

Mark A. Murcko, Paul R. Caron, M. Murcko, 1996, Cell.

Inhibition of IMPDH by mycophenolic acid: dissection of forward and reverse pathways using capillary electrophoresis.

K. Wilson, M. Sintchak, J. Fulghum, 1996, Biochemistry.

Crystallization of serine carboxypeptidases.

K. Wilson, S. Remington, D. Liao, 1990, Journal of molecular biology.

Comparative X-ray structures of the major binding protein for the immunosuppressant FK506 (tacrolimus) in unliganded form and in complex with FK506 and rapamycin.

M. Murcko, K. Wilson, S. Rotstein, 1995, Acta crystallographica. Section D, Biological crystallography.

Structural Basis for the Autoinhibition and STI-571 Inhibition of c-Kit Tyrosine Kinase*

K. Wilson, Biching Sang, C. Mol, 2004, Journal of Biological Chemistry.

2.2 A resolution structure of the amino-terminal half of HIV-1 reverse transcriptase (fingers and palm subdomains).

B. Strandberg, K. Wilson, Z. Dauter, 1994, Structure.

The structure of phosphorylated p38gamma is monomeric and reveals a conserved activation-loop conformation.

K. Wilson, M. Fitzgibbon, T. Fox, 1999, Structure.

A single amino acid substitution makes ERK2 susceptible to pyridinyl imidazole inhibitors of p38 MAP kinase

K. Wilson, M. Su, S. Pazhanisamy, 1998, Protein science : a publication of the Protein Society.

Crystal structure of JNK3: a kinase implicated in neuronal apoptosis.

P. Caron, K. Wilson, M. Su, 1998, Structure.

Crystal Structure of p38 Mitogen-activated Protein Kinase*

Paul R. Caron, P. Caron, K. Wilson, 1996, The Journal of Biological Chemistry.

Ancestral lysozymes reconstructed, neutrality tested, and thermostability linked to hydrocarbon packing

Brian W. Matthews, Jack F. Kirsch, Allan C. Wilson, 1990, Nature.

Substrate and Inhibitor Specificity of Interleukin-1β-converting Enzyme and Related Caspases*

K. Wilson, T. Fox, S. Raybuck, 1997, The Journal of Biological Chemistry.

Inhibitors of p38 MAP kinase: therapeutic intervention in cytokine-mediated diseases.

G. Bemis, K. Wilson, M. Su, 1999, Current medicinal chemistry.

Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme

Tom Alber, Brian W. Matthews, B. Matthews, 1988, Nature.

Comparison of the crystal structure of bacteriophage T4 lysozyme at low, medium, and high ionic strengths

B. Matthews, K. Wilson, J. Bell, 1991, Proteins.

Crystallographic and Genetic Approaches Toward the Design of Proteins of Enhanced Thermostability

B. Matthews, M. Matsumura, H. Nicholson, 1990 .

The Discovery of VX-745: A Novel and Selective p38α Kinase Inhibitor.

Huai Gao, Yow-Ming Wang, Yow-Ming C Wang, 2011, ACS medicinal chemistry letters.

Recent results and new hardware developments for protein crystal growth in microgravity

A. D. Clark, A. Sacco, K. Moore, 1994 .