Hong Liu

发表

Virtual screening on natural products for discovering active compounds and target information.

Kaixian Chen, Hualiang Jiang, Jianhua Shen, 2003, Current medicinal chemistry.

Focused combinatorial library design based on structural diversity, druglikeness and binding affinity score.

Jian Zhang, Xiaomin Luo, Weiliang Zhu, 2005, Journal of combinatorial chemistry.

Strategy for discovering chemical inhibitors of human cyclophilin a: focused library design, virtual screening, chemical synthesis and bioassay.

Jian Zhang, Xiaomin Luo, Weiliang Zhu, 2006, Journal of combinatorial chemistry.

Discovering novel chemical inhibitors of human cyclophilin A: Virtual screening, synthesis, and bioassay

Hualiang Jiang, Xu Shen, Hong Liu, 2005, Bioorganic & Medicinal Chemistry.

Asymmetric total synthesis and identification of tetrahydroprotoberberine derivatives as new antipsychotic agents possessing a dopamine D(1), D(2) and serotonin 5-HT(1A) multi-action profile.

Kaixian Chen, Hualiang Jiang, Hong Liu, 2013, Bioorganic & medicinal chemistry.

Web-image driven best views of 3D shapes

Hong Liu, Hua Huang, Lei Zhang, 2011, The Visual Computer.

Development of a novel class of B-Raf(V600E)-selective inhibitors through virtual screening and hierarchical hit optimization.

Cheng Luo, Weiliang Zhu, Mingyue Zheng, 2012, Organic & biomolecular chemistry.

Network modelling reveals the mechanism underlying colitis-associated colon cancer and identifies novel combinatorial anti-cancer targets

Cheng Luo, Bairong Shen, Zhongjie Liang, 2015, Scientific Reports.

Design, synthesis, and interaction study of quinazoline-2(1H)-thione derivatives as novel potential Bcl-xL inhibitors.

Fang Liu, Kaixian Chen, Hualiang Jiang, 2010, Journal of medicinal chemistry.

Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors

Hualiang Jiang, Yechun Xu, Zhènglì Shí, 2020, Nature.

Deep Learning Enhancing Kinome-Wide Polypharmacology Profiling: Model Construction and Experiment Validation.

Kaixian Chen, Hualiang Jiang, Hong Liu, 2019, Journal of medicinal chemistry.

Design, synthesis, and biological evaluation of 2-(phenoxyaryl)-3-urea derivatives as novel P2Y1 receptor antagonists.

Hong Liu, Huaiyu Yang, Jingjing Peng, 2018, European journal of medicinal chemistry.

Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination.

Honglin Li, Kunqian Yu, Mingyue Zheng, 2009, Journal of medicinal chemistry.

Structure-based discovery of potassium channel blockers from natural products: virtual screening and electrophysiological assay testing.

Yang Li, Jianmin Yue, Suxin Zheng, 2003, Chemistry & biology.

Development of cell-active N6-methyladenosine RNA demethylase FTO inhibitor.

Cheng Luo, Fei Ye, Haiyan Li, 2012, Journal of the American Chemical Society.

Nucleocapsid protein of SARS coronavirus tightly binds to human cyclophilin A

Cheng Luo, Jingkang Shen, Suxin Zheng, 2004, Biochemical and Biophysical Research Communications.

Fluorine in pharmaceutical industry: fluorine-containing drugs introduced to the market in the last decade (2001-2011).

Hong Liu, Jiang Wang, C. del Pozo, 2014, Chemical reviews.

Structural and Functional Analysis of Laninamivir and its Octanoate Prodrug Reveals Group Specific Mechanisms for Influenza NA Inhibition

George F. Gao, Feng Gao, Jun Liu, 2011, PLoS pathogens.

The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site

Jianhua He, Di Liu, Christopher J Vavricka, 2010, Nature Structural &Molecular Biology.

Selective Synthesis of 5,6‐Dihydroindolo[1,2‐a]quinoxalines and 6,7‐Dihydroindolo[2,3‐c]quinolines by Orthogonal Copper and Palladium Catalysis

Hong Liu, M. Zheng, Jiang Wang, 2013 .

[Application of methyl in drug design].

Hong Liu, Haifeng Sun, Hong Liu, 2013, Yao xue xue bao = Acta pharmaceutica Sinica.

Sulfoximines-Assisted Rh(III)-Catalyzed C–H Activation and Intramolecular Annulation for the Synthesis of Fused Isochromeno-1,2-Benzothiazines Scaffolds under Room Temperature

Hong Liu, Jian Li, Chunpu Li, 2020, Molecules.

Configurationally Stable (S)‐ and (R)‐α‐Methylproline‐Derived Ligands for the Direct Chemical Resolution of Free Unprotected β3‐Amino Acids

Hong Liu, Shengbin Zhou, Jiang Wang, 2018 .

Inhibitory mode of 1,5-diarylpyrazole derivatives against cyclooxygenase-2 and cyclooxygenase-1: molecular docking and 3D QSAR analyses.

Bing Xiong, Kaixian Chen, Jianhua Shen, 2002, Journal of medicinal chemistry.

A removable directing group-assisted Rh(iii)-catalyzed direct C–H bond activation/annulation cascade to synthesize highly fused isoquinolines

Hong Liu, Yu Zhou, Xu Han, 2020 .

Optimizing chemical reaction conditions using deep learning: a case study for the Suzuki–Miyaura cross-coupling reaction

Xiaomin Luo, Kaixian Chen, Hualiang Jiang, 2020, Organic Chemistry Frontiers.

Palladium-Catalyzed Regioselective 2-Carbethoxyethylation of 1HÃ¢Â€Â“ Indoles By C-H Activation: One-Step Synthesis of Ethyl 2-(1H-Indol-2-Yl) Acetates

Hong Liu, Yi Zhang, Jiang Wang, 2013 .

Novel therapeutics based on inhibiting the interaction of glycogen phosphorylase and GL-subunit of glycogen-associated protein phosphatase 1: WO2009127723

Hong Liu, Lei Zhang, 2010, Expert opinion on therapeutic patents.

Palladium-Catalyzed C2-Acylation of Indoles with α-Diketones Assisted by the Removable N-(2-Pyrimidyl) Group

Hong Liu, Xiaoming Wu, Chunpu Li, 2015 .

Silver-catalyzed intramolecular hydroamination of alkynes in aqueous media: efficient and regioselective synthesis for fused benzimidazoles

Hualiang Jiang, Xu Zhang, Hong Liu, 2011 .

Microwave-assisted synthesis of quinazolinone derivatives by efficient and rapid iron-catalyzed cyclization in water

Hualiang Jiang, Xu Zhang, Hong Liu, 2009 .

Gold-catalyzed intramolecular hydroamination of terminal alkynes in aqueous media: efficient and regioselective synthesis of indole-1-carboxamides

Hualiang Jiang, Xu Zhang, Hong Liu, 2009 .

Recyclable and Stable α-Methylproline-Derived Chiral Ligands for the Chemical Dynamic Kinetic Resolution of free C,N-Unprotected α-Amino Acids

Hong Liu, Shengbin Zhou, Liang Zhao, 2019, Molecules.

Green and Facile Assembly of Diverse Fused N-Heterocycles Using Gold-Catalyzed Cascade Reactions in Water

Hong Liu, Jiang Wang, Jin-hai Yu, 2019, Molecules.

Design, Synthesis, and Pharmacological Evaluation of Novel Multisubstituted Pyridin-3-amine Derivatives as Multitargeted Protein Kinase Inhibitors for the Treatment of Non-Small Cell Lung Cancer.

Hong Liu, M. Zheng, M. Geng, 2017, Journal of medicinal chemistry.

Highly selective intramolecular addition of C–N and S–N bonds to alkynes catalyzed by palladium: a practical access to two distinct functional indoles

Hong Liu, Liang Zhao, Jiang Wang, 2016 .

[Diversity-oriented synthesis and its application in drug discovery].

Hong Liu, Lei Zhang, Mingfang Zheng, 2015, Yao xue xue bao = Acta pharmaceutica Sinica.

Microwave Heating in Organic Synthesis and Drug Discovery

Hong Liu, Lei Zhang, 2013 .

Microwave dielectric heating in modern organic synthesis and drug discovery

Hong Liu, Lei Zhang, 2011 .

Pyrazolidine-3,5-dione derivatives as potent non-steroidal agonists of farnesoid X receptor: virtual screening, synthesis, and biological evaluation.

Kaixian Chen, Hualiang Jiang, Jianhua Shen, 2008, Bioorganic & medicinal chemistry letters.

Construction of highly enantiopure β,β-diaryl substituted glycine containing two contiguous stereocenters via asymmetric 1,6-conjugate addition

Hong Liu, Liang Zhao, Liang Zhao, 2018, Tetrahedron.

Identification of novel inhibitors of histone acetyltransferase hMOF through high throughput screening.

Hong Liu, Shien Liu, C. Luo, 2018, European journal of medicinal chemistry.

What're in A Scene? Towards the Computational Best View of 3D Scene

Hong Liu, Lei Zhang, Hua Huang, 2012 .

Design, synthesis and biological evaluation of 6-deoxy O-spiroketal C-arylglucosides as novel renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes.

Hong Liu, Jiang Wang, Jingya Li, 2019, European journal of medicinal chemistry.

Small‐Molecule Therapeutics for Ebola Virus (EBOV) Disease Treatment

Hong Liu, Jiang Wang, V. Soloshonok, 2016 .

Synthesis and Evaluation of Anti-HIV-1 Activities of Novel 7-Hydroxy-1,3-dioxo-2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-4-carboxylate Derivatives

Hong Liu, Jian Li, Yu Zhou, 2014 .

Microwave-assisted efficient and convenient synthesis of 2,4(1H,3H)-quinazolinediones and 2-thioxoquinazolines.

Hualiang Jiang, Hong Liu, Hongbin Sun, 2008, Journal of combinatorial chemistry.

Ionic‐Liquid‐Supported Total Synthesis of Sansalvamide A Peptide

Hualiang Jiang, Hong Liu, Yu Zhou, 2008 .

Cobalt-catalyzed C(sp3)–H/C(sp2)–H oxidative coupling between alkanes and benzamides

Hong Liu, Chunpu Li, Bao Wang, 2018, RSC advances.

Asymmetric Synthesis of Chiral Trifluoromethyl Containing Heterocyclic Amino Acids

Hong Liu, Shengbin Zhou, Liang Zhao, 2017 .

Nickel-Catalyzed ortho-C-H Thiolation of N-Benzoyl α-Amino Acid Derivatives.

Hong Liu, Feng Gao, Jiang Wang, 2016, The Journal of organic chemistry.

Rapid access to difluoroalkylated pyrrolobenzodiazepines via a Pd-catalyzed C–H difluoroalkylation/cyclization cascade reaction

Hong Liu, Chunpu Li, Yang Gao, 2019, Organic Chemistry Frontiers.

Cp*Rh(III)-Catalyzed C-H Bond Difluorovinylation of Indoles with α,α-Difluorovinyl Tosylate.

Hong Liu, Chunpu Li, Dechuan Wang, 2019, The Journal of organic chemistry.

Efficient iron-catalyzed N-arylation of aryl halides with amines.

Hualiang Jiang, Hong Liu, Jinyi Xu, 2008, Organic letters.

Tailor-Made α-Amino Acids in the Pharmaceutical Industry: Synthetic Approaches to (1R,2S)-1-Amino-2-vinylcyclopropane-1-carboxylic Acid (Vinyl-ACCA)

Hong Liu, V. Soloshonok, J. L. Aceña, 2016 .

Chemical kinetic resolution of unprotected β-substituted β-amino acids using recyclable chiral ligands.

Hong Liu, Shengbin Zhou, Jiang Wang, 2014, Angewandte Chemie.

An expedient Pd/DBU mediated cyanation of aryl/heteroaryl bromides with K4[Fe(CN)6].

Kaixian Chen, Hualiang Jiang, Hong Liu, 2012, Chemical communications.

Rapid generation of privileged substructure-based compound libraries with structural diversity and drug-likeness.

Hong Liu, M. Zheng, Lei Zhang, 2014, ACS combinatorial science.

Highly selective C–H bond activation of N-arylbenzimidamide and divergent couplings with diazophosphonate compounds: a catalyst-controlled selective synthetic strategy for 3-phosphorylindoles and 4-phosphorylisoquinolines

Hong Liu, Yu Zhou, Chenglin Wu, 2019, Organic Chemistry Frontiers.

Discovery of 5-Benzylidene-2-phenyl-1,3-dioxane-4,6-diones as Highly Potent and Selective SIRT1 Inhibitors.

Hong Liu, Chunpu Li, Dongxiang Liu, 2021, ACS medicinal chemistry letters.

Benzamide derivatives as dual-action hypoglycemic agents that inhibit glycogen phosphorylase and activate glucokinase.

Hualiang Jiang, Honglin Li, Hong Liu, 2009, Bioorganic & medicinal chemistry.

Structural optimization and biological evaluation of 1,5-disubstituted pyrazole-3-carboxamines as potent inhibitors of human 5-lipoxygenase

Hualiang Jiang, Hong Liu, M. Zheng, 2016, Acta pharmaceutica Sinica. B.

Diastereoselective Michael reaction of chiral nickel(II) glycinate with nitroalkenes for asymmetric synthesis of β-substituted α,γ-diaminobutyric acid derivatives in water

Hualiang Jiang, Hong Liu, Haifeng Sun, 2011, Amino Acids.

Design, Synthesis, and Biological Evaluation of 8-Mercapto-3,7-Dihydro-1H-Purine-2,6-Diones as Potent Inhibitors of SIRT1, SIRT2, SIRT3, and SIRT5

Hong Liu, Zhifei Wang, Chunpu Li, 2020, Molecules.

Asymmetric Synthesis of (2S,3S)-α-(1-Oxoisoindolin-3-yl)glycines under Low-Basicity "Kinetic" Control.

Hong Liu, Shengbin Zhou, Jiang Wang, 2015, The Journal of organic chemistry.

Recyclable Ligands for the Non-Enzymatic Dynamic Kinetic Resolution of Challenging α-Amino Acids.

Hong Liu, Shengbin Zhou, Jiang Wang, 2015, Angewandte Chemie.

Chemical Dynamic Thermodynamic Resolution and S/R Interconversion of Unprotected Unnatural Tailor-made α-Amino Acids.

Hong Liu, Shengbin Zhou, Jiang Wang, 2015, The Journal of organic chemistry.

Copper-mediated C-H(sp²)/C-H(sp³) coupling of benzoic acid derivatives with ethyl cyanoacetate: an expedient route to an isoquinolinone scaffold.

Hong Liu, Wei Zhu, Dengyou Zhang, 2014, Chemical communications.

Asymmetric Synthesis of Chiral α‐Substituted Mercaptoglycine Derivatives via α‐Sulfenylation of Ni(II) Complex of Glycine and S‐Substituted 4‐Methylbenzenesulfonothioate

Hong Liu, Jia Li, Shengbin Zhou, 2017 .

Synthesis of Pyrrolo[1,2-a]quinoxalines via gold(I)-mediated cascade reactions.

Hualiang Jiang, Hong Liu, Yu Zhou, 2011, ACS combinatorial science.

Gold(I)‐Catalyzed One‐Pot Tandem Coupling/Cyclization: An Efficient Synthesis of Pyrrolo‐/Pyrido[2,1‐b]benzo[d][1,3]oxazin‐ 1‐ones

Hualiang Jiang, Hong Liu, Yu Zhou, 2010 .

A simple copper-catalyzed two-step one-pot synthesis of indolo[1,2-a]quinazoline

Hong Liu, Chunpu Li, Lei Zhang, 2014, Beilstein journal of organic chemistry.

Ru(ii)-catalyzed C6-selective C–H acylmethylation of pyridones using sulfoxonium ylides as carbene precursors

Hong Liu, Jiang Wang, Zhiyu Li, 2020, RSC advances.

Advanced asymmetric synthesis of (1R,2S)-1-amino-2-vinylcyclopropanecarboxylic acid by alkylation/cyclization of newly designed axially chiral Ni(II) complex of glycine Schiff base

Hong Liu, Jiang Wang, H. Moriwaki, 2015, Amino Acids.

Design, synthesis, and biological evaluation of 1,2,5-oxadiazole-3-carboximidamide derivatives as novel indoleamine-2,3-dioxygenase 1 inhibitors.

Hong Liu, P. Sun, Jiang Wang, 2020, European journal of medicinal chemistry.

Discovering potent inhibitors against c-Met kinase: molecular design, organic synthesis and bioassay.

Kaixian Chen, Hualiang Jiang, Hong Liu, 2012, Organic & biomolecular chemistry.

Recent Advances in the Addition of Amide/Sulfonamide Bonds to Alkynes

Hong Liu, Jiang Wang, Fei Zhao, 2019, Molecules.

Catalytic and catalyst-free diboration of alkynes

Hong Liu, Yu Zhou, Jingwei Zhao, 2017 .

Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II-III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas.

Wei Zhu, Hong Liu, Yu Zhou, 2016, Chemical reviews.

Ruthenium(ii)-catalyzed selective C–H bond activation of imidamides and coupling with sulfoxonium ylides: an efficient approach for the synthesis of highly functional 3-ketoindoles

Hong Liu, Yu Zhou, Chenglin Wu, 2019, Organic Chemistry Frontiers.

Palladium-catalyzed intramolecular addition of C–N bond to alkynes: a novel approach to 3-diketoindoles

Hong Liu, Jiang Wang, Chenglin Wu, 2015 .

Discovery of novel 2-aminopyridine-3-carboxamides as c-Met kinase inhibitors.

Hualiang Jiang, Hong Liu, Zhongjie Liang, 2012, Bioorganic & medicinal chemistry.

POSSIBLE PATHWAY(S) OF TESTOSTERONE EGRESS FROM THE ACTIVE SITE OF CYTOCHROME P450 2B1: A STEERED MOLECULAR DYNAMICS SIMULATION

Weihua Li, Frauke Gräter, Hualiang Jiang, 2005, Drug Metabolism and Disposition.

Sulfoximines Assisted Rh(III)-Catalyzed C-H Activation/Annulation Cascade to Synthesize Highly Fused Indeno-1,2-benzothiazines.

Hong Liu, Jian Li, Yu Zhou, 2021, The Journal of organic chemistry.

Rh(III)-Catalyzed Dual C-H Functionalization/Cyclization Cascade by a Removable Directing Group: A Method for Synthesis of Polycyclic Fused Pyrano[de]Isochromenes.

Hong Liu, Yu Zhou, Dechuan Wang, 2020, The Journal of organic chemistry.

Ir(iii)-Catalyzed direct C-H functionalization of N-phenylacetamide with α-diazo quinones: a novel strategy for producing 2-hydroxy-2'-amino-1,2'-biaryl scaffolds.

Kaixian Chen, Hong Liu, Wenhao Dai, 2020, Chemical communications.

Ruthenium(II)-Catalyzed C-H Acylmethylation between (Hetero)arenes and α-Cl Ketones/Sulfoxonium Ylides.

Hong Liu, Jiang Wang, Chenglin Wu, 2019, The Journal of organic chemistry.

Rhodium‐Catalyzed C−H Activation/Annulation Cascade of Aryl Oximes and Propargyl Alcohols to Isoquinoline N ‐Oxides

Hong Liu, Yu Zhou, Run-Ming Wang, 2021 .

Efficient copper-promoted N-arylations of aryl halides with amines.

Weiliang Zhu, Kaixian Chen, Hualiang Jiang, 2008, Journal of combinatorial chemistry.

Rh(III)-Catalyzed C–H Bond Activation for the Construction of Heterocycles with sp3-Carbon Centers

Hong Liu, Yu Zhou, Xiong Xie, 2019, Catalysts.

Recent advances in the trifluoromethylation methodology and new CF3-containing drugs

Hong Liu, Jiang Wang, V. Soloshonok, 2014 .

Efficient iron/copper cocatalyzed alkynylation of aryl iodides with terminal alkynes.

Kaixian Chen, Hualiang Jiang, Hong Liu, 2008, The Journal of organic chemistry.

Ni(ii)-catalyzed mono-selective ortho-arylation of unactivated aryl C–H bonds utilizing amino acids as a directing group

Hong Liu, F. Gao, Feng Gao, 2019, RSC advances.

Cobalt(iii)-catalyzed site-selective C–H amidation of pyridones and isoquinolones

Hong Liu, F. Gao, Chunpu Li, 2018, RSC advances.

Cu( ii )-catalyzed C6-selective C–H thiolation of 2-pyridones using air as the oxidant

Hualiang Jiang, Hong Liu, Chunpu Li, 2016 .

The facile construction of the phthalazin-1(2H)-one scaffold via copper-mediated C–H(sp2)/C–H(sp) coupling under mild conditions

Hong Liu, Shengbin Zhou, Wei Zhu, 2015, Beilstein journal of organic chemistry.

Synthesis and Structures of (S)- and (r)-2-[3-Cyano-4-(2-Thienyl)-5,6,7, 8-Tetrahydroquinolin-2-Ylsulfanyl]-3-Methyl-N-Phenylbutyramide

Kaixian Chen, Hualiang Jiang, Hong Liu, 2006 .

Copper(I)-catalyzed one-pot synthesis of 2H-1,4-benzoxazin-3-(4H)-ones from o-halophenols and 2-chloroacetamides.

Hualiang Jiang, Hong Liu, Yu Zhou, 2009, The Journal of organic chemistry.

Gold‐catalyzed Rapid Construction of Nitrogen‐containing Heterocyclic Compound Library with Scaffold Diversity and Molecular Complexity

Hong Liu, Yu Zhou, Jingwei Zhao, 2019, Advanced Synthesis & Catalysis.

Au(I)/Ag(I)-catalyzed cascade approach for the synthesis of benzo[4,5]imidazo[1,2-c]pyrrolo[1,2-a]quinazolinones.

Hualiang Jiang, Hong Liu, Yu Zhou, 2013, The Journal of organic chemistry.

Gold‐Catalyzed Tandem Reaction in Water: An Efficient and Convenient Synthesis of Fused Polycyclic Indoles.

Hualiang Jiang, Hong Liu, Yu Zhou, 2012 .

Gold-catalyzed tandem reaction in water: an efficient and convenient synthesis of fused polycyclic indoles

Hualiang Jiang, Hong Liu, Yu Zhou, 2012 .

Silver- and gold-mediated domino transformation: a strategy for synthesizing benzo[e]indolo[1,2-a]pyrrolo/pyrido[2,1-c][1,4]diazepine-3,9-diones.

Hualiang Jiang, Xu Zhang, Hong Liu, 2011, The Journal of organic chemistry.

Gold(I)-catalyzed tandem transformation: a simple approach for the synthesis of pyrrolo/pyrido[2,1-a][1,3]benzoxazinones and pyrrolo/pyrido[2,1-a]quinazolinones.

Hualiang Jiang, Hong Liu, Haifeng Sun, 2010, The Journal of organic chemistry.

Gold-catalyzed one-pot cascade construction of highly functionalized pyrrolo[1,2-a]quinolin-1(2H)-ones.

Hualiang Jiang, Hong Liu, Yu Zhou, 2009, The Journal of organic chemistry.

Gold- and Silver-Catalyzed Intramolecular Hydroamination of Terminal Alkynes: Water-Triggered Chemo- and Regioselective Synthesis of Fused Tricyclic Xanthines

Hualiang Jiang, Xu Zhang, Hong Liu, 2009 .

Design, Synthesis, and Biological Evaluation of Peptidomimetic Aldehydes as Broad-Spectrum Inhibitors against Enterovirus and SARS-CoV-2

Kaixian Chen, Hualiang Jiang, Yechun Xu, 2021, Journal of medicinal chemistry.

Recent advances in the gold-catalyzed additions to C–C multiple bonds

Hong Liu, Yu Zhou, He Huang, 2011, Beilstein journal of organic chemistry.

Rapid and selective access to three distinct sets of indole-based heterocycles from a single set of Ugi-adducts under microwave heating.

Hong Liu, M. Zheng, Lei Zhang, 2013, Chemical communications.

One-Pot NBS-Promoted Synthesis of Imidazoles and Thiazoles from Ethylarenes in Water

Hong Liu, Jiang Wang, Huajian Zhu, 2019, Molecules.

Highly diastereoselective synthesis of 3-indolylglycines via an asymmetric oxidative heterocoupling reaction of a chiral nickel(II) complex and indoles.

Hualiang Jiang, Xu Zhang, Hong Liu, 2013, Chemical communications.

Synthesis of Pyrazolo[1,2‐a]cinnolines via Rhodium(III)‐Catalyzed [4+2] Annulation Reactions of Pyrazolidinones with Sulfoxonium Ylides

Hong Liu, Xiong Xie, Shulei Hu, 2021 .

Ruthenium-Catalyzed C–H Activations for the Synthesis of Indole Derivatives

Hong Liu, Yu Zhou, Chunpu Li, 2020, Catalysts.

Rhodium(III)-Catalyzed [4+2] Annulation via C-H Activation: Synthesis of Multi-Substituted Naphthalenone Sulfoxonium Ylides

Hong Liu, Jiang Wang, Xu Han, 2019, Molecules.

Direct Synthesis of 3-Acylindoles through Rhodium(III)-Catalyzed Annulation of N-Phenylamidines with α-Cl Ketones.

Hong Liu, Jian Li, Yu Zhou, 2018, Organic letters.

Rhodium(III)‐Catalyzed C‐H Activation of Benzoylacetonitriles and Cyclization with Sulfoxonium Ylides to Naphthols

Hong Liu, Yu Zhou, Yilang Cheng, 2018 .

Rh(III)-Catalyzed C-H Activation of Benzoylacetonitriles and Tandem Cyclization with Diazo Compounds to Substituted Benzo[ de]chromenes.

Hong Liu, Yu Zhou, Chunmei Zhang, 2018, Organic letters.

Cp*Rh(III)‐Catalyzed Directed C−H Methylation and Arylation of Quinoline N‐Oxides at the C‐8 Position

Hong Liu, Chunpu Li, Bao Wang, 2017 .

Ruthenium-Catalyzed Redox-Neutral [4 + 1] Annulation of Benzamides and Propargyl Alcohols via C–H Bond Activation

Hong Liu, Shengbin Zhou, Yu Zhou, 2017 .

Palladium-Catalyzed Intramolecular Addition of C-N Bond to Alkynes: A Novel Approach to 3-Diketoindoles.

Hong Liu, Jiang Wang, Chenglin Wu, 2016 .

Palladium-catalyzed difunctionalization of alkynes via C-N and S-N cleavages: a versatile approach to highly functional indoles.

Hong Liu, Lei Zhang, Fei Zhao, 2014, Organic letters.

Microwave‐Assisted Dehalogenation of α‐Haloketones by Zinc and Ammonium Chloride in Alcohol

Hualiang Jiang, Hong Liu, Xiao-min Luo, 2008 .

Synthesis of 2-phenylnaphthalenes through gold-catalyzed dimerization via a highly selective carbon nucleophile pathway.

Hualiang Jiang, Hong Liu, Yu Zhou, 2011, The Journal of organic chemistry.

A Rh(iii)-catalyzed C–H activation/regiospecific annulation cascade of benzoic acids with propargyl acetates to unusual 3-alkylidene-isochromanones

Hong Liu, Yu Zhou, Bin Xu, 2021 .

The Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as Novel Covalent Fibroblast Growth Factor Receptor (FGFR) Inhibitors by Rational Drug Design.

Hualiang Jiang, Yechun Xu, Hong Liu, 2019, Journal of medicinal chemistry.

Ligand-free iron/copper cocatalyzed N-arylations of aryl halides with amines under microwave irradiation

Kaixian Chen, Hualiang Jiang, Hong Liu, 2010 .

New selective O-debenzylation of phenol with Mg/MeOH

Hualiang Jiang, Jianhua Shen, Xu Zhang, 2005 .

Microwave‐Assisted Dehalogenation of α‐Haloketones by Zinc and Ammonium Chloride in Alcohol.

Hualiang Jiang, Hong Liu, Xiao-min Luo, 2008 .

Microwave-assisted rapid synthesis of 2,6,9-substituted purines.

Kaixian Chen, Hualiang Jiang, Hong Liu, 2007, Journal of combinatorial chemistry.

Transformation of Aryl Acyloin O‐Alkyl and O‐Phenyl Derivatives to Ketones

Kaixian Chen, Hualiang Jiang, Hong Liu, 2007 .

Microwave‐Assisted Synthesis of 2‐Amino‐thiophene‐3‐Carboxylic Derivatives Under Solvent‐Free Conditions

Hualiang Jiang, Jianhua Shen, Hong Liu, 2005 .

N-Heterocyclic Carbene Catalytic [4 + 2] Cyclization of 3-Alkylenyloxindoles with Enals: γ-Carbon Activation for Enantioselective Assembly of Spirocarbocyclic Oxindoles.

Hong Liu, Yu Zhou, H. Yao, 2016, The Journal of organic chemistry.

Regioselective synthesis of 3-benzazepinones and unexpected 5-bromo-3-benzazepinones.

Hualiang Jiang, Hong Liu, Yu Zhou, 2010, The Journal of organic chemistry.

Silver‐Catalyzed Intramolecular Cyclization of o‐(1‐Alkynyl)benzamides: Efficient Synthesis of (1H)‐Isochromen‐1‐imines

Hualiang Jiang, Hong Liu, Yu Zhou, 2009 .

Rh(III)-Catalyzed Annulation of Boc-Protected Benzamides with Diazo Compounds: Approach to Isocoumarins

Hong Liu, Chunpu Li, Guangyu Dong, 2019, Molecules.

Enantioselective N‐Heterocyclic Carbene‐Catalyzed [3+3] Annulation of α,β‐Unsaturated Esters with Methyl Ketoimine

Hong Liu, Yu Zhou, H. Yao, 2016 .

Metal-free tandem reaction in water: An efficient and regioselective synthesis of 3-hydroxyisoindolin-1-ones

Hualiang Jiang, Hong Liu, Jian Li, 2010 .

Rhodium(III)-Catalyzed C-H Alkenylation/Directing Group Migration for the Regio- and Stereoselective Synthesis of Tetrasubstituted Alkenes.

Hong Liu, Wenhao Dai, Fei Zhao, 2020, Organic letters.

Rh(III)-Catalyzed Hydroarylation of Alkyne MIDA Boronates via C-H Activation of Indole Derivatives.

Hong Liu, Chunpu Li, Xinhong Yu, 2019, The Journal of organic chemistry.

Recent Advances in the Synthesis of Heterocycles via Gold-catalyzed Cascade Reactions: A Review

Hong Liu, F. Gao, Yu Zhou, 2017 .

Design, Synthesis, and Biological Evaluation of Indoline and Indole Derivatives as Potent and Selective α1A-Adrenoceptor Antagonists.

Hong Liu, Yu Zhou, Jiang Wang, 2016, Journal of medicinal chemistry.

Rhodium(III)-Catalyzed Site-Selective C-H Alkylation and Arylation of Pyridones Using Organoboron Reagents.

Hualiang Jiang, Hong Liu, Jiang Wang, 2016, Organic letters.

Rhodium(III)-Catalyzed C-H Alkenylation: Access to Maleimide-Decorated Tryptophan and Tryptophan-Containing Peptides.

Hong Liu, Jingjing Peng, Chunpu Li, 2020, Organic letters.

A simple and convenient copper-catalyzed tandem synthesis of quinoline-2-carboxylates at room temperature.

Kaixian Chen, Hualiang Jiang, Hong Liu, 2009, The Journal of organic chemistry.

Total Synthesis of Cytosporone B

Hualiang Jiang, Xu Shen, Hong Liu, 2010 .

Synthesis of Highly Fused Pyrano[2,3-b]pyridines via Rh(III)-Catalyzed C-H Activation and Intramolecular Cascade Annulation under Room Temperature.

Hong Liu, Yu Zhou, Xiong Xie, 2020, The Journal of organic chemistry.

Rhodium(III)-Catalyzed Redox-Neutral [3+3] Annulation of N-nitrosoanilines with Cyclopropenones: A Traceless Approach to Quinolin-4(1H)-One Scaffolds

Kaixian Chen, Hong Liu, Yu Zhou, 2020, Molecules.

Rhodium(III)-Catalyzed C-H Activation of α-Iminonitriles or α-Imino Esters and Cyclization with Acrylates to 2 H-Isoindoles.

Hong Liu, Yu Zhou, Bin Xu, 2018, The Journal of organic chemistry.

Rh(III)-Catalyzed [5 + 1] Annulation of Indole-enaminones with Diazo Compounds To Form Highly Functionalized Carbazoles.

Hong Liu, Yu Zhou, Haoran Zhu, 2021, Organic letters.

Pd(II)-catalyzed direct functionalization of C–H bonds of benzamides for synthesis of 1,1-difluoro-1-alkenes

Hong Liu, Chunpu Li, Peng Wan, 2016 .

Enantioselective Assembly of Spirolactones through NHC-Catalyzed Remote γ-Carbon Addition of Enals with Isatins.

Hong Liu, Yu Zhou, H. Yao, 2016, ACS combinatorial science.

Direct access to pyrido/pyrrolo[2,1-b]quinazolin-9(1H)-ones through silver-mediated intramolecular alkyne hydroamination reactions

Xu Zhang, Hong Liu, Yu Zhou, 2015, Beilstein journal of organic chemistry.

Microwave‐Assisted One‐Step Synthesis of Acetophenones via Palladium‐Catalyzed Regioselective Arylation of Vinyloxytrimethylsilane

Hualiang Jiang, Hong Liu, Haifeng Sun, 2012 .

A Mannich/cyclization cascade process for the asymmetric synthesis of spirocyclic thioimidazolidineoxindoles.

Hong Liu, Yu Zhou, H. Cai, 2014, Chemical communications.

A Method for Synthesis of 3-Hydroxy-1-indanones via Cu-Catalyzed Intramolecular Annulation Reactions.

Hong Liu, Yu Zhou, Huabei Zhang, 2018, The Journal of organic chemistry.

Indole derivatives as potent inhibitors of 5-lipoxygenase: design, synthesis, biological evaluation, and molecular modeling.

Kaixian Chen, Hualiang Jiang, Hong Liu, 2007, Bioorganic & medicinal chemistry letters.

Microwave‐Assisted Efficient and Convenient Synthesis of 2,4(1H,3H)‐Quinazolinediones and 2‐Thioxoquinazolines.

Hualiang Jiang, Hong Liu, Hongbin Sun, 2008 .

Application of Sulfonyl in Drug Design

Hong Liu, Xiao Ding, Fei Zhao, 2016, Chinese Journal of Organic Chemistry.

Cell-permeable iminocoumarine-based fluorescent dyes for mitochondria.

Kaixian Chen, Hualiang Jiang, Hong Liu, 2011, Organic letters.

Asymmetric Synthesis of α‐Amino Acids under Operationally Convenient Conditions

Hong Liu, C. Bolm, V. Soloshonok, 2014 .

Enantioselective synthesis of 2-substitued-tetrahydroisoquinolin-1-yl glycine derivatives via oxidative cross-dehydrogenative coupling of tertiary amines and chiral nickel(II) glycinate.

Hong Liu, Shengbin Zhou, Jiang Wang, 2013, The Journal of organic chemistry.

Highly diastereo- and enantioselective synthesis of syn-β-substituted tryptophans via asymmetric Michael addition of a chiral equivalent of nucleophilic glycine and sulfonylindoles.

Hualiang Jiang, Hong Liu, Shengbin Zhou, 2011, Chemical communications.

Design and synthesis of small molecule RhoA inhibitors: a new promising therapy for cardiovascular diseases?

Weiliang Zhu, Jian Li, Honglin Li, 2011, Journal of medicinal chemistry.

Simultaneous 2-O-deacetylation and 4-amination of peracetylated Neu5Ac: application to the synthesis of (4 -> 4)-piperazine derivatives linked sialic acid dimers

Hualiang Jiang, Hong Liu, Yu Zhou, 2008 .

Gold(I)‐Catalyzed Cascade for Synthesis of Pyrrolo[1,2‐a:2′,1′‐c]‐/Pyrido[2,1‐c]pyrrolo[1,2‐a]quinoxalinones

Hualiang Jiang, Hong Liu, Yu Zhou, 2010 .

Gold-catalyzed Michael addition/intramolecular annulation cascade: an effective pathway for the chemoselective- and regioselective synthesis of tetracyclic indole derivatives in water

Hualiang Jiang, Jinyi Xu, Hualiang Jiang, 2013 .

Asymmetric Michael addition of N-tert-butanesulfinyl imidate with α,β-unsaturated diesters: scope and application to the synthesis of indanone derivatives.

Hong Liu, Zeng Li, Yu Zhou, 2013, Organic letters.

Highly Enantioselective Michael Addition of 2-Oxindole- 3-carboxylate Esters to Nitroolefins Promoted by Cinchona Alkaloid-Thiourea-Brønsted Acid Cocatalysts

Hualiang Jiang, Hong Liu, W. Qian, 2012 .

New p-methylsulfonamido phenylethylamine analogues as class III antiarrhythmic agents: design, synthesis, biological assay, and 3D-QSAR analysis.

Xiaomin Luo, Kaixian Chen, Hualiang Jiang, 2002, Journal of medicinal chemistry.

‘One-pot’ Synthesis of Dihydrobenzo[4,5][1,3]oxazino[2,3-a]isoquinolines via a Silver(I)-Catalyzed Cascade Approach

Hualiang Jiang, Hong Liu, Yu Zhou, 2013, Molecules.

One-pot metal-free synthesis of highly substituted pyrroles from 2-acetyl-3-methylene-1,4-dicarbonyl compounds and primary amines via TBHP and activated carbon oxidative aromatization of dihydropyrrole

Hong Liu, Haifeng Sun, Yu Zhou, 2014 .

Novel thiophene derivatives as PTP1B inhibitors with selectivity and cellular activity.

Hualiang Jiang, Xu Shen, Xu Zhang, 2010, Bioorganic & medicinal chemistry.

Metal-free synthesis of 2-substituted (N, O, C) benzothiazoles via an intramolecular C-S bond formation.

Hualiang Jiang, Hong Liu, Yu Zhou, 2010, Journal of combinatorial chemistry.

Synthesis and biological evaluation of 2-amino-5-aryl-3-benzylthiopyridine scaffold based potent c-Met inhibitors.

Cheng Luo, Ying Wang, Zhongjie Liang, 2013, Bioorganic & medicinal chemistry.

Construction of highly enantioenriched spirocyclopentaneoxindoles containing four consecutive stereocenters via thiourea-catalyzed asymmetric Michael–Henry cascade reactions

Hong Liu, Jian Li, Yu Zhou, 2017, Beilstein journal of organic chemistry.

Synthesis of bis-α,α'-amino acids through diastereoselective bis-alkylations of chiral Ni(II)-complexes of glycine.

Hong Liu, Jiang Wang, H. Moriwaki, 2013, Organic & biomolecular chemistry.

Regio-selective and stereo-selective hydrosilylation of internal alkynes catalyzed by ruthenium complexes

Hong Liu, Wenhao Dai, Chunpu Li, 2018, RSC advances.

Asymmetric one-pot sequential Mannich/hydroamination reaction by organo- and gold catalysts: synthesis of spiro[pyrrolidin-3,2'-oxindole] derivatives.

Hualiang Jiang, Hong Liu, Z. Yao, 2013, Organic letters.

Recent approaches for asymmetric synthesis of α-amino acids via homologation of Ni(II) complexes

Hong Liu, Jiang Wang, H. Moriwaki, 2017, Amino Acids.

Analysis of crystallographic structures of Ni(ii) complexes of α-amino acid Schiff bases: elucidation of the substituent effect on stereochemical preferences.

Hong Liu, Jiang Wang, H. Moriwaki, 2017, Dalton transactions.

Synthesis of polysubstituted β-amino cyclohexane carboxylic acids via Diels–Alder reaction using Ni(II)-complex stabilized β-alanine derived dienes

Xiaomin Luo, Hualiang Jiang, Hong Liu, 2012, Amino Acids.

Catalytic System‐Controlled Divergent Reaction Strategies for the Construction of Diversified Spiropyrazolone Skeletons from Pyrazolidinones and Diazopyrazolones

Hong Liu, Yu Zhou, Chunpu Li, 2021, Angewandte Chemie.

Catalytic System-Controlled Divergent Reaction Strategies for the Construction of Diversified Spiropyrazolone Skeletons from Pyrazolidinones and Diazopyrazolones.

Hong Liu, Yu Zhou, Chunpu Li, 2021, Angewandte Chemie.

Microwave-assisted synthesis of 5,6-dihydroindolo[1,2-a]quinoxaline derivatives through copper-catalyzed intramolecular N-arylation

Hong Liu, Shengbin Zhou, Hailong Liu, 2013, Beilstein journal of organic chemistry.

A metal-free method for the facile synthesis of indanones via the intramolecular hydroacylation of 2-vinylbenzaldehyde

Hong Liu, Yu Zhou, Chunpu Li, 2021 .

Chemical dynamic kinetic resolution and S/R interconversion of unprotected α-amino acids.

Hong Liu, H. Moriwaki, V. Soloshonok, 2014, Angewandte Chemie.

Ligand‐Free Iron/Copper Cocatalyzed N‐Arylations of Aryl Halides with Amines under Microwave Irradiation.

Kaixian Chen, Hualiang Jiang, Hong Liu, 2010 .

Efficient iron/copper cocatalyzed S-arylations of thiols with aryl halides.

Hualiang Jiang, Hong Liu, He Huang, 2009, Journal of combinatorial chemistry.

Copper-catalyzed intramolecular cyclization to N-substituted 1,3-dihydrobenzimidazol-2-ones.

Hualiang Jiang, Hong Liu, Hongbin Sun, 2008, Organic letters.

I2-induced cascade cyclization and dearomatization of indoles for the highly efficient synthesis of iodinated and vinylic spiroindolenines

Hong Liu, Yu Zhou, Qi Liu, 2021, Green Chemistry.

An unusual de-nitro reduction of 2-substituted-4-nitroquinolines

Hualiang Jiang, Hong Liu, Jian Li, 2006 .

Synthesis of Pyrrolo[1,2-a]quinoxalines via gold(I)-mediated cascade reactions.

Hualiang Jiang, Hong Liu, Yu Zhou, 2011, ACS combinatorial science.

New Selective O‐Debenzylation of Phenol with Mg/MeOH.

Hualiang Jiang, Jianhua Shen, Xu Zhang, 2005 .

Discovery and mechanism study of SIRT1 activators that promote the deacetylation of fluorophore-labeled substrate.

Kaixian Chen, Hualiang Jiang, Hong Liu, 2013, Journal of medicinal chemistry.

Microwave‐Assisted Synthesis of 2‐Aminothiophene‐3‐carboxylic Derivatives under Solvent‐Free Conditions.

Hualiang Jiang, Jianhua Shen, Hong Liu, 2005 .

Transformation of Aryl Acyloin O-Alkyl and O-Phenyl Derivatives to Ketones.

Kaixian Chen, Hualiang Jiang, Hong Liu, 2007 .

Diastereoselective Michael reaction of chiral nickel(II) glycinate with nitroalkenes for asymmetric synthesis of β-substituted α,γ-diaminobutyric acid derivatives in water

Hualiang Jiang, Hong Liu, Haifeng Sun, 2012, Amino Acids.

Preparation of α-alkyl-β-amino acids via β-alanine Ni(II) complex.

Hualiang Jiang, Hong Liu, Jiang Wang, 2011, The Journal of organic chemistry.

One novel quinoxaline derivative as a potent human cyclophilin A inhibitor shows highly inhibitory activity against mouse spleen cell proliferation

Li Zhang, Yu Qin, Jingkang Shen, 2006, Bioorganic & Medicinal Chemistry.

Molecular Basis of NDM-1, a New Antibiotic Resistance Determinant

Cheng Luo, Mingyue Zheng, Zhongjie Liang, 2011, PloS one.

Copper-Mediated C—H(sp2)/C—H(sp3) Coupling of Benzoic Acid Derivatives with Ethyl Cyanoacetate: An Expedient Route to an Isoquinolinone Scaffold.

Wei Zhu, Hong Liu, Dengyou Zhang, 2015 .

Synthesis of C-4-modified zanamivir analogs as neuraminidase inhibitors and their anti-AIV activities.

Weiliang Zhu, Jian Li, Ky-Youb Nam, 2012, European journal of medicinal chemistry.

Gold(I)-catalyzed cascade approach for the synthesis of tryptamine-based polycyclic privileged scaffolds as α1-adrenergic receptor antagonists.

Hong Liu, Zeng Li, Yu Zhou, 2013, The Journal of organic chemistry.

Anthraquinone Derivatives as Potent Inhibitors of c-Met Kinase and the Extracellular Signaling Pathway.

Hualiang Jiang, Hong Liu, M. Zheng, 2013, ACS medicinal chemistry letters.

Syntheses of triazole-modified zanamivir analogues via click chemistry and anti-AIV activities.

Weiliang Zhu, Jian Li, Mingyue Zheng, 2006, Bioorganic & medicinal chemistry letters.

An Effective Synthetic Entry to Fused Benzimidazoles via Iodocyclization

Hualiang Jiang, Xu Zhang, Hong Liu, 2011 .

An Effective Synthetic Entry to Fused Benzimidazoles via Iodocyclization.

Hualiang Jiang, Xu Zhang, Hong Liu, 2011 .

Asymmetric synthesis of chiral heterocyclic amino acids via the alkylation of the Ni(II) complex of glycine and alkyl halides.

Hong Liu, Shengbin Zhou, Jiang Wang, 2014, The Journal of organic chemistry.

N-Heterocyclic Carbene Catalyzed Enantioselective [3 + 2] Dearomatizing Annulation of Saturated Carboxylic Esters with N-Iminoisoquinolinium Ylides.

Hong Liu, Yu Zhou, Pengfei Zhang, 2018, Journal of Organic Chemistry.

Palladium-catalyzed [4 + 3] dearomatizing cycloaddition reaction of N-iminoquinolinium ylides

Kaixian Chen, Hong Liu, Wenhao Dai, 2020 .

Discovery of Pyrazolo[3,4-d]pyridazinone Derivatives as Selective DDR1 Inhibitors via Deep Learning Based Design, Synthesis, and Biological Evaluation.

Hualiang Jiang, Hong Liu, M. Zheng, 2021, Journal of medicinal chemistry.

FTY720 Induces Apoptosis of M2 Subtype Acute Myeloid Leukemia Cells by Targeting Sphingolipid Metabolism and Increasing Endogenous Ceramide Levels

Hualiang Jiang, Hong Liu, Yuan-fang Liu, 2014, PloS one.

Recent Advances in Neuraminidase Inhibitor Development as Anti‐influenza Drugs

Fei Zhao, Mingyue Zheng, Rolf Hilgenfeld, 2012, ChemMedChem.

Ir(I)-Catalyzed C−H Glycosylation for Synthesis of 2-Indolyl-C-Deoxyglycosides

Hong Liu, Dan Zhang, Xiong Xie, 2021 .

Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FGFR inhibitors

Hualiang Jiang, Hong Liu, M. Zheng, 2020, Acta pharmaceutica Sinica. B.

[Lead compound optimization strategy(5) – reducing the hERG cardiac toxicity in drug development].

Hong Liu, Shengbin Zhou, Jiang Wang, 2016, Yao xue xue bao = Acta pharmaceutica Sinica.

Identification and synthesis of N-(thiophen-2-yl) benzamide derivatives as BRAF(V600E) inhibitors.

Hualiang Jiang, Hong Liu, R. Marmorstein, 2013, Bioorganic & medicinal chemistry letters.

Simulating the interactions of toxins with K+ channels.

Xiaomin Luo, Kunqian Yu, Kaixian Chen, 2004, Current pharmaceutical design.

Novel 5-(benzyloxy)pyridin-2(1H)-one derivatives as potent c-Met inhibitors.

Weiliang Zhu, Hualiang Jiang, Hong Liu, 2013, Bioorganic & medicinal chemistry letters.

Pd(II)-Catalyzed Directed γ-C(sp3)-H Arylation between Free β2-Amino Esters and β3-Amino Esters and Aryl Iodides Using a Catalytic Transient Directing Group.

Hong Liu, Jiang Wang, Zhaohui Wang, 2020, The Journal of organic chemistry.

The inhibitory effects of DC031050, a class III antiarrhythmic agent with high selectivity for hERG channels, on three neuronal potassium channels

Hualiang Jiang, G. Hu, Hong Liu, 2012 .

Tryptophan-containing dipeptide derivatives as potent PPARgamma antagonists: design, synthesis, biological evaluation, and molecular modeling.

Xiaomin Luo, Weiliang Zhu, Hualiang Jiang, 2008, European journal of medicinal chemistry.

γ-Carbon Activation through N-Heterocyclic Carbene/Brønsted Acids Cooperative Catalysis: A Highly Enantioselective Route to δ-Lactams.

Hong Liu, Yu Zhou, Yonglong Xiao, 2015, Organic letters.

QSAR analyses on avian influenza virus neuraminidase inhibitors using CoMFA, CoMSIA, and HQSAR

Hong Liu, Xiaomin Luo, Weiliang Zhu, 2006, J. Comput. Aided Mol. Des..

Recent approaches for asymmetric synthesis of α-amino acids via homologation of Ni(II) complexes

Hong Liu, Jiang Wang, H. Moriwaki, 2017, Amino Acids.

Chemical Resolution of C, N-Unprotected α-Substituted β-Amino Acids Using Stable and Recyclable Proline-Derived Chiral Ligands.

Hong Liu, Shengbin Zhou, Jiang Wang, 2018, The Journal of organic chemistry.

Purely Chemical Approach for Preparation of d-α-Amino Acids via (S)-to-(R)-Interconversion of Unprotected Tailor-Made α-Amino Acids.

Hong Liu, Shengbin Zhou, Wenhao Dai, 2016, The Journal of organic chemistry.

Asymmetric Synthesis of Aromatic and Heteroaromatic α‐Amino Acids Using a Recyclable Axially Chiral Ligand

Hong Liu, Shengbin Zhou, Jiang Wang, 2016 .

Asymmetric synthesis of α-(1-oxoisoindolin-3-yl)glycine: synthetic and mechanistic challenges.

Hong Liu, Shengbin Zhou, Jiang Wang, 2015, Chemical communications.

Asymmetric synthesis of sterically and electronically demanding linear ω-trifluoromethyl containing amino acids via alkylation of chiral equivalents of nucleophilic glycine and alanine.

Hong Liu, Shengbin Zhou, Jiang Wang, 2011, The Journal of organic chemistry.

Application of nickel(II) complexes to the efficient synthesis of α- or β-amino acids.

Kaixian Chen, Hualiang Jiang, Hong Liu, 2011, Chimia.

Structural modifications of 5,6-dihydroxypyrimidines with anti-HIV activity.

Hong Liu, Zeng Li, Yu Zhou, 2012, Bioorganic & medicinal chemistry letters.

Reduced Catalytic Activity of P450 2A6 Mutants with Coumarin: A Computational Investigation.

Weihua Li, Yun Tang, Hualiang Jiang, 2009, Journal of chemical theory and computation.

The type IA topoisomerase catalytic cycle: A normal mode analysis and molecular dynamics simulation

Xiaomin Luo, Jianhua Shen, Hong Liu, 2008, Proteins.

Structure-based design and synthesis of C-1- and C-4-modified analogs of zanamivir as neuraminidase inhibitors.

Weiliang Zhu, Jian Li, Mingyue Zheng, 2013, Journal of medicinal chemistry.

Computational simulations of interactions of scorpion toxins with the voltage-gated potassium ion channel.

Xiaomin Luo, Kunqian Yu, Hualiang Jiang, 2004, Biophysical journal.

Design, Synthesis, and Biological Evaluation of Novel Tetrahydroprotoberberine Derivatives (THPBs) as Selective α1A-Adrenoceptor Antagonists.

Hualiang Jiang, B. Shoichet, Honglin Li, 2016, Journal of medicinal chemistry.

Design , Synthesis , and Biological Evaluation of Novel Tetrahydroprotoberberine Derivatives ( THPBs ) as Selective α 1 A-Adrenoceptor Antagonists

Hualiang Jiang, B. Shoichet, Honglin Li, 2016 .

Discovering potassium channel blockers from synthetic compound database by using structure-based virtual screening in conjunction with electrophysiological assay.

Weiliang Zhu, Yang Li, Suxin Zheng, 2007, Journal of medicinal chemistry.

[Lead compound optimization strategy (4)--improving blood-brain barrier permeability through structural modification].

Hong Liu, Yu Zhou, Jiang Wang, 2014, Yao xue xue bao = Acta pharmaceutica Sinica.

Probing ligand binding modes of human cytochrome P450 2J2 by homology modeling, molecular dynamics simulation, and flexible molecular docking

Weiliang Zhu, Weihua Li, Yun Tang, 2008, Proteins.

Enterovirus 71 and Coxsackievirus A16 3C Proteases: Binding to Rupintrivir and Their Substrates and Anti-Hand, Foot, and Mouth Disease Virus Drug Design

Hualiang Jiang, Hong Liu, F. Gao, 2011, Journal of Virology.

The gating charge pathway of an epilepsy-associated potassium channel accommodates chemical ligands

Zhuxi Chen, Ping Li, Hao Li, 2013, Cell Research.

Palladium-Catalyzed Ortho-Alkoxylation of N-Benzoyl α-Amino Acid Derivatives at Room Temperature.

Hong Liu, Chunpu Li, Jiang Wang, 2017, The Journal of organic chemistry.

Efficient dehydrative sialylation of C-4-aminated sialyl-hemiketal donors with Ph2SO/Tf2O.

Hualiang Jiang, Hong Liu, E. Feng, 2009, The Journal of organic chemistry.

Simultaneous Stereoselective 4-Amination with Cyclic Secondary Amines and 2-O-Deacetylation of Peracetylated Sialic Acid Derivatives.

Hualiang Jiang, Hong Liu, Jian Li, 2007 .

Simultaneous stereoselective 4-amination with cyclic secondary amines and 2-O-deacetylation of peracetylated sialic acid derivatives

Hualiang Jiang, Hong Liu, Jian Li, 2007 .

VideoWeb: Space-Time Aware Presentation of a Videoclip Collection

Hong Liu, Hua Huang, Lei Zhang, 2014, IEEE Journal on Emerging and Selected Topics in Circuits and Systems.

[Lead compound optimization strategy (3)--Structure modification strategies for improving water solubility].

Hong Liu, Zeng Li, Yu Zhou, 2014, Yao xue xue bao = Acta pharmaceutica Sinica.

Structural optimization and biological evaluation of substituted bisphenol A derivatives as beta-amyloid peptide aggregation inhibitors.

Cheng Luo, Zhongjie Liang, Xin Xie, 2010, Journal of medicinal chemistry.

Synthesis and Anti-HIV-1 Activity Evaluation for Novel 3a,6a-Dihydro-1H-pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives

Hong Liu, Jian Li, Yu Zhou, 2016, Molecules.

Design, synthesis, and pharmacological evaluation of novel tetrahydroprotoberberine derivatives: selective inhibitors of dopamine D₁ receptor.

Hualiang Jiang, Hong Liu, Xuechu Zhen, 2012, Bioorganic & medicinal chemistry.

Discovering benzamide derivatives as glycogen phosphorylase inhibitors and their binding site at the enzyme.

Hualiang Jiang, Honglin Li, Hong Liu, 2007, Bioorganic & medicinal chemistry.

Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies.

Hualiang Jiang, Honglin Li, Hong Liu, 2011, European journal of medicinal chemistry.

Copper-Catalyzed Synthesis of α-Keto Amides from Sulfoxonium Ylides.

Hong Liu, Yu Zhou, Xinghua Wang, 2023, The Journal of organic chemistry.

Inhibitor discovery targeting the intermediate structure of beta-amyloid peptide on the conformational transition pathway: implications in the aggregation mechanism of beta-amyloid peptide.

Jianpeng Ma, Xu Shen, Kaixian Chen, 2006, Biochemistry.

Possible Pathway(s) of Metyrapone Egress from the Active Site of Cytochrome P450 3A4: A Molecular Dynamics Simulation

Weiliang Zhu, Weihua Li, Yun Tang, 2007, Drug Metabolism and Disposition.

Mutagenesis and molecular dynamics suggest structural and functional roles for residues in the N-terminal portion of the cytochrome P450 2B1 I helix.

Hong Liu, J. Halpert, E. Scott, 2004, Archives of biochemistry and biophysics.

Identification and synthesis of N'-(2-oxoindolin-3-ylidene)hydrazide derivatives against c-Met kinase.

Kaixian Chen, Hualiang Jiang, Hong Liu, 2011, Bioorganic & medicinal chemistry letters.

Advanced asymmetric synthesis of (1R,2S)-1-amino-2-vinylcyclopropanecarboxylic acid by alkylation/cyclization of newly designed axially chiral Ni(II) complex of glycine Schiff base

Hong Liu, Jiang Wang, H. Moriwaki, 2016, Amino Acids.

Synthesis of (S)-, (R)-, and (rac)-2-amino-3,3-bis(4-fluorophenyl)propanoic acids and an evaluation of the DPP IV inhibitory activity of Denagliptin diastereomers

Hualiang Jiang, Hong Liu, Jia Li, 2008 .

Synthesis of 4-Aryl-2(5H)-furanones by Gold(I)-Catalyzed Intramolecular Annulation

Kaixian Chen, Hong Liu, Haifeng Sun, 2011 .

Discovering Novel α‐aminoacyl‐Containing Proline Derivatives with Potent and Selective Inhibitory Activity Against Dipeptidyl Peptidase IV: Design, Synthesis, Biological Evaluation, and Molecular Modeling

Hong Liu, Xiaodong Zhang, Zeng Li, 2012, Chemical biology & drug design.

Design, Synthesis, Structure–Activity Relationships, and Docking Studies of 1‐(γ‐1,2,3‐Triazol Substituted Prolyl)‐(S)‐3,3‐Difluoropyrrolidines as a Novel Series of Potent and Selective Dipeptidyl Peptidase‐4 Inhibitors

Hong Liu, Zeng Li, Jiang Wang, 2013, Chemical biology & drug design.

Rh(III)-Catalyzed Successive C-H Activations of 2-Phenyl-3H-indoles and Cyclization Cascades to Construct Highly Fused Indole Heteropolycycles.

Hao Wang, Hong Liu, Yu Zhou, 2023, Organic Letters.

Computational Screening for Active Compounds Targeting Protein Sequences: Methodology and Experimental Validation

Hong Liu, Xiaomin Luo, Weiliang Zhu, 2011, J. Chem. Inf. Model..

Rh(III)-Catalyzed C-H Activation and [4+1+1] Sequential Cyclization Cascade to Give Highly Fused Indano[1,2-b]azirines.

Hong Liu, Yu Zhou, Yungen Xu, 2022, Organic letters.

Cobalt(II)-Catalyzed C(sp3)-C(sp3) Coupling for the Direct Stereoselective Synthesis of 2-Deoxy-C-glycosides from Glycals.

Hong Liu, Jiang Wang, Jingjing Wang, 2023, Angewandte Chemie.

Design, Synthesis, and Biological Evaluation of Novel Imidazo[1,2-a]pyridine Derivatives as Potent c-Met Inhibitors.

X. Chen, Hong Liu, M. Geng, 2015, ACS medicinal chemistry letters.

Application of Nitrile in Drug Design

Hong Liu, Jiang Wang, 2012 .

Web-image driven best views of 3D shapes

Hong Liu, Hua Huang, Lei Zhang, 2012, The Visual Computer.

[Application of phosphates and phosphonates prodrugs in drug research and development].

Hualiang Jiang, Hong Liu, Lei Zhang, 2013, Yao xue xue bao = Acta pharmaceutica Sinica.

Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II-III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas.

Hong Liu, Yu Zhou, Jiang Wang, 2016, Chemical reviews.

Rapid and efficient Pd-catalyzed Sonogashira coupling of aryl chlorides.

Kaixian Chen, Hualiang Jiang, Hong Liu, 2008, The Journal of organic chemistry.

Fluorine in pharmaceutical industry: fluorine-containing drugs introduced to the market in the last decade (2001-2011).

Hong Liu, Jiang Wang, C. del Pozo, 2014, Chemical reviews.

Highly alpha-selective synthesis of sialyl spirohydantoins by regiospecific domino condensation/O-->N acyl migration/N-sialylation of carbodiimides with peracetylated sialic acid.

Hualiang Jiang, Hong Liu, E. Feng, 2010, The Journal of organic chemistry.

Purely Chemical Approach for Preparation of d-α-Amino Acids via (S)-to-(R)-Interconversion of Unprotected Tailor-Made α-Amino Acids.

Hong Liu, Shengbin Zhou, Wenhao Dai, 2016, The Journal of organic chemistry.

Chemical dynamic kinetic resolution and S/R interconversion of unprotected α-amino acids.

Hong Liu, H. Moriwaki, V. Soloshonok, 2014, Angewandte Chemie.

Chemical kinetic resolution of unprotected β-substituted β-amino acids using recyclable chiral ligands.

Hong Liu, Shengbin Zhou, Jiang Wang, 2014, Angewandte Chemie.

Why are oseltamivir and zanamivir effective against the newly emerged influenza A virus (A/H1N1)?

Cheng Luo, Jianpeng Ma, Weiliang Zhu, 2009, Cell Research.

γ-Carbon Activation through N-Heterocyclic Carbene/Brønsted Acids Cooperative Catalysis: A Highly Enantioselective Route to δ-Lactams.

Hong Liu, Yu Zhou, Yonglong Xiao, 2015, Organic letters.

Silver- and gold-mediated intramolecular cyclization to substituted tetracyclic isoquinolizinium hexafluorostilbates.

Hualiang Jiang, Hong Liu, Yu Zhou, 2010, The Journal of organic chemistry.

Highly enantio- and diastereoselective mannich reactions of chiral Ni(II) glycinates with amino sulfones. Efficient asymmetric synthesis of aromatic alpha,beta-diamino acids.

Hualiang Jiang, Ting Shi, Hong Liu, 2008, The Journal of organic chemistry.

Synthesis of C-4-modified zanamivir analogs as neuraminidase inhibitors and their anti-AIV activities.

Hualiang Jiang, Ning Li, Hong Liu, 2012, European journal of medicinal chemistry.