Qiang Xu

发表

Discovering novel chemical inhibitors of human cyclophilin A: Virtual screening, synthesis, and bioassay

Hualiang Jiang, Xu Shen, Hong Liu, 2005, Bioorganic & Medicinal Chemistry.

Plant cyclopeptide RA-V kills human breast cancer cells by inducing mitochondria-mediated apoptosis through blocking PDK1-AKT interaction.

Lu Wang, Wei Chen, Yang Sun, 2013, Toxicology and applied pharmacology.

Astilbin prevents concanavalin A-induced liver injury by reducing TNF-alpha production and T lymphocytes adhesion.

Qiang Xu, Jun Wang, Ying Zhao, 2004, The Journal of pharmacy and pharmacology.

Astilbin prevents concanavalin A‐induced liver injury by reducing TNF‐α production and T lymphocyte adhesion

Qiang Xu, Jun Wang, Ying Zhao, 2004 .

Effective Virtual Screening Strategy toward heme-containing proteins: Identification of novel IDO1 inhibitors.

Qiang Xu, Wenjie Guo, Yihua Zhang, 2019, European journal of medicinal chemistry.

Fas-Associated Protein with Death Domain Regulates Notch Signaling during Muscle Regeneration

Qiang Xu, Wei Cheng, Rong Zhang, 2015, Cells Tissues Organs.

Novel monofunctional platinum (II) complex Mono-Pt induces apoptosis-independent autophagic cell death in human ovarian carcinoma cells, distinct from cisplatin

Qiang Xu, Yang Zhang, Wei Chen, 2013, Autophagy.

Dietary fructose-induced gut dysbiosis promotes mouse hippocampal neuroinflammation: a benefit of short-chain fatty acids

Qiang Xu, Jian-Mei Li, Rong Yu, 2019, Microbiome.

A novel synthetic oleanolic acid derivative with amino acid conjugate suppresses tumour growth by inducing cell cycle arrest

Qiang Xu, Jian-Xin Li, Yang Sun, 2007, The Journal of pharmacy and pharmacology.

Inhibition of ursolic acid on calcium-induced mitochondrial permeability transition and release of two proapoptotic proteins

Qiang Xu, Z. Qian, Jing Gao, 2005 .

Beauvericin Ameliorates Experimental Colitis by Inhibiting Activated T Cells via Downregulation of the PI3K/Akt Signaling Pathway

Qiang Xu, C. Qian, Yanhong Gu, 2013, PloS one.

Role of four major components in the effect of Si‐Ni‐San, a traditional Chinese prescription, against contact sensitivity in mice

Qiang Xu, Yang Sun, Li Zhang, 2006, The Journal of pharmacy and pharmacology.

Protective effects of 18β-glycyrrhetinic acid on LPS-induced injury in intestinal epithelial cells

Qiang Xu, Xianying Fang, Xuefeng Wu, 2014 .

Decrease of Functional Activated T and B Cells and Treatment of Glomerulonephitis in Lupus-Prone Mice Using a Natural Flavonoid Astilbin

Qiang Xu, Yan Shen, Xuefeng Wu, 2015, PloS one.

Obaculactone suppresses Th1 effector cell function through down-regulation of T-bet and prolongs skin graft survival in mice.

Qiang Xu, Qi Zhang, Yan Shen, 2010, Biochemical pharmacology.

Unprecedented immunosuppressive polyketides from Daldinia eschscholzii, a mantis-associated fungus.

Qiang Xu, H. Ge, Y. Song, 2008, Angewandte Chemie.

SHP2 inhibition triggers anti-tumor immunity and synergizes with PD-1 blockade

Qiang Xu, L. Zhong, Yanhong Gu, 2018, Acta pharmaceutica Sinica. B.

Quercetin inhibits the invasion of murine melanoma B16-BL6 cells by decreasing pro-MMP-9 via the PKC pathway

Qiang Xu, Xianming Zhang, Shao-Peng Huang, 2003, Cancer Chemotherapy and Pharmacology.

Loss of hnRNP A1 in murine skeletal muscle exacerbates high-fat diet-induced onset of insulin resistance and hepatic steatosis

Qiang Xu, Xuefeng Wu, Yang Sun, 2019, Journal of molecular cell biology.

Quercetin inhibits the invasion of murine melanoma B16-BL6 cells by decreasing pro-MMP-9 via the PKC pathway

Qiang Xu, Xianming Zhang, Shao-Peng Huang, 2007, Cancer Chemotherapy and Pharmacology.

Annexin A5 regulates hepatic macrophage polarization via directly targeting PKM2 and ameliorates NASH

Qiang Xu, Kangkang Luo, Tao Pang, 2020, Redox biology.

Role of CXCR3 signaling in response to anti-PD-1 therapy

Qiang Xu, Xiao Han, Yanhong Gu, 2019, EBioMedicine.

Porphyromonas gingivalis lipopolysaccharide inhibits the osteoblastic differentiation of preosteoblasts by activating Notch1 signaling

Qiang Xu, M. Fan, Qingsong Ye, 2010, Journal of cellular physiology.

Phosphatase-independent functions of SHP2 and its regulation by small molecule compounds.

Qiang Xu, Wenjie Guo, 2020, Journal of pharmacological sciences.

Roseotoxin B Improves Allergic Contact Dermatitis through a Unique Anti-Inflammatory Mechanism Involving Excessive Activation of Autophagy in Activated T Lymphocytes.

Qiang Xu, Wei Chen, Yan Shen, 2016, The Journal of investigative dermatology.

Discovery of a new class of immunosuppressants from Trichothecium roseum co-inspired by cross-kingdom similarity in innate immunity and pharmacophore motif.

Qiang Xu, S. Ng,, Yang Sun, 2013, Chemistry, an Asian journal.

Targeting protein phosphatases for the treatment of inflammation-related diseases: From signaling to therapy

Qiang Xu, Yang Sun, Lisha Zhou, 2022, Signal Transduction and Targeted Therapy.

Targeting SHP2 as a promising strategy for cancer immunotherapy.

Qiang Xu, Yang Sun, Jiao Qu, 2019, Pharmacological research.

Systematic study of imidazoles inhibiting IDO1 via the integration of molecular mechanics and quantum mechanics calculations.

Qiang Xu, Wenjie Guo, F. Wang, 2017, European journal of medicinal chemistry.

Discovery of potent IDO1 inhibitors derived from tryptophan using scaffold-hopping and structure-based design approaches.

Qiang Xu, Wenjie Guo, F. Wang, 2017, European journal of medicinal chemistry.

Apigenin induces autophagic cell death in human papillary thyroid carcinoma BCPAP cells.

Qiang Xu, Yang Sun, Jie Zheng, 2015, Food & function.

Phosphatase of regenerating liver-3 promotes motility and metastasis of mouse melanoma cells.

Qiang Xu, Xiang Gao, H. Zeng, 2004, The American journal of pathology.

Phosphatase of Regenerating Liver-3 Localizes to Cyto-Membrane and Is Required for B16F1 Melanoma Cell Metastasis In Vitro and In Vivo

Qiang Xu, R. Song, Shao-Xian Cao, 2009, PloS one.

A Novel Chromone Derivative with Anti-Inflammatory Property via Inhibition of ROS-Dependent Activation of TRAF6-ASK1-p38 Pathway

Qiang Xu, C. Qian, Lu Wang, 2012, PloS one.

A natural compound jaceosidin ameliorates endoplasmic reticulum stress and insulin resistance via upregulation of SERCA2b.

Qiang Xu, Qi Zhang, Yan Shen, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Dictamni extract induces apoptosis of activated hepatic stellate cells via TAT 1 and attenuates liver fibrosis in mice

Qiang Xu, Gong Chen, Xuefeng Wu, 2011 .

Cortex Dictamni extract induces apoptosis of activated hepatic stellate cells via STAT1 and attenuates liver fibrosis in mice.

Qiang Xu, Gong Chen, Yan Shen, 2011, Journal of ethnopharmacology.

High expression of sarcoplasmic/endoplasmic reticulum Ca(2+)-ATPase 2b blocks cell differentiation in human liposarcoma cells.

Qiang Xu, Lu Wang, Yanhong Gu, 2014, Life sciences.

Apatinib suppresses tumor progression and enhances cisplatin sensitivity in esophageal cancer via the Akt/β-catenin pathway

Qiang Xu, J. Wu, Yanhong Gu, 2020, Cancer Cell International.

CPT-11 activates NLRP3 inflammasome through JNK and NF-κB signalings.

Qiang Xu, Yanhong Gu, Qian Li, 2015, Toxicology and applied pharmacology.

The Antimicrobial Peptide MAF-1A Acts on the Transcriptional Response of Candida parapsilosis

Qiang Xu, Fuxun Yu, Wei Li, 2019 .

The Antioxidant Procyanidin Reduces Reactive Oxygen Species Signaling in Macrophages and Ameliorates Experimental Colitis in Mice

Qiang Xu, Liang Hu, Wen-tao Liu, 2018, Front. Immunol..

Tyrosine phosphatase SHP2 exacerbates psoriasis‐like skin inflammation in mice via ERK5‐dependent NETosis

Qiang Xu, Yan Ding, Yang Sun, 2022, MedComm.

Quercetin inhibits the invasion and mobility of murine melanoma B16-BL6 cells through inducing apoptosis via decreasing Bcl-2 expression

Qiang Xu, I. Saiki, Xianming Zhang, 2004, Clinical & Experimental Metastasis.

Astilbin suppresses delayed‐type hypersensitivity by inhibiting lymphocyte migration

Qiang Xu, Ting Chen, Yuchen Cai, 2003, The Journal of pharmacy and pharmacology.

Metabolite profiling of astilbin in rat sera using UPLC/MS(E) and impact of its metabolites on immunosuppressive activity.

Qiang Xu, C. Qian, Yan Shen, 2013, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Identification of a new metabolite of astilbin, 3'-O-methylastilbin, and its immunosuppressive activity against contact dermatitis.

Qiang Xu, Ting Chen, Jianxin Li, 2007, Clinical chemistry.

Andrographolide sulfate inhibited NF-κB activation and alleviated pneumonia induced by poly I:C in mice

Qiang Xu, Yang Sun, Wenjie Guo, 2020, Journal of Pharmacological Sciences.

A genetically encoded copper(I) sensor based on engineered structural distortion of EGFP.

Qiang Xu, Yan Shen, Yi Cao, 2012, Chemical communications.

Andrographolide alleviates Parkinsonism in MPTP‐PD mice via targeting mitochondrial fission mediated by dynamin‐related protein 1

Qiang Xu, Z. Qin, Yang Sun, 2019, British journal of pharmacology.

Astilbin inhibits contact hypersensitivity through negative cytokine regulation distinct from cyclosporin A.

Qiang Xu, M. Fei, Xuefeng Wu, 2005, The Journal of allergy and clinical immunology.

EGFR inhibitor-driven endoplasmic reticulum stress-mediated injury on intestinal epithelial cells.

Qiang Xu, Yanhong Gu, Yan Shen, 2014, Life sciences.

Highly expressed SERCA2 triggers tumor cell autophagy and is a druggable vulnerability in triple-negative breast cancer

Qiang Xu, Yan Shen, Jian Gao, 2022, Acta pharmaceutica Sinica. B.

Novel immunomodulatory properties of cirsilineol through selective inhibition of IFN-gamma signaling in a murine model of inflammatory bowel disease.

Qiang Xu, Yan Shen, Xuefeng Wu, 2010, Biochemical pharmacology.

Disruption of chaperone-mediated autophagy-dependent degradation of MEF2A by oxidative stress-induced lysosome destabilization

Jing Wu, Qiang Xu, M. Fei, 2014, Autophagy.

T lymphocyte SHP2-deficiency triggers anti-tumor immunity to inhibit colitis-associated cancer in mice

Qiang Xu, Yanhong Gu, Yang Sun, 2016, Oncotarget.

Ameliorates Murine Experimental Colitis Cytoplasm via Phosphorylated SHP-2 Selective Sequestration of STAT1 in the

Qiang Xu, Yan Shen, Xuefeng Wu, 2012 .

Selective Sequestration of STAT1 in the Cytoplasm via Phosphorylated SHP-2 Ameliorates Murine Experimental Colitis

Qiang Xu, Yanhong Gu, Yan Shen, 2012, The Journal of Immunology.

Rebuilding the balance of STAT1 and STAT3 signalings by fusaruside, a cerebroside compound, for the treatment of T-cell-mediated fulminant hepatitis in mice.

Qiang Xu, Xuefeng Wu, Yang Sun, 2012, Biochemical pharmacology.

SBF-1 preferentially inhibits growth of highly malignant human liposarcoma cells.

Qiang Xu, Xianying Fang, Wei Chen, 2018, Journal of pharmacological sciences.

The superior folding of a RANTES analogue expressed in lactobacilli as compared to mammalian cells reveals a promising system to screen new RANTES mutants.

Qiang Xu, P. Lusso, L. Vangelista, 2009, Protein expression and purification.

A Chinese rhesus macaque (Macaca mulatta) model for vaginal Lactobacillus colonization and live microbicide development

Brigitte E. Sanders-Beer, D. Hamer, Qiang Xu, 2009, Journal of medical primatology.

Engineering of a Human Vaginal Lactobacillus Strain for Surface Expression of Two-Domain CD4 Molecules

Qiang Xu, Xiaowen Liu, Peter P. Lee, 2008, Applied and Environmental Microbiology.

Sunitinib impairs the proliferation and function of human peripheral T cell and prevents T-cell-mediated immune response in mice.

Qiang Xu, Yanhong Gu, Yang Sun, 2010, Clinical immunology.

CXCR6 is required for antitumor efficacy of intratumoral CD8+ T cell

Qiang Xu, Yang Sun, Z. Tian, 2021, Journal for ImmunoTherapy of Cancer.

Icotinib, a potent and specific EGFR tyrosine kinase inhibitor, inhibits growth of squamous cell carcinoma cell line A431 through negatively regulating AKT signaling.

Qiang Xu, Xianying Fang, Wei Chen, 2013, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Suppression of NF-κB signaling and NLRP3 inflammasome activation in macrophages is responsible for the amelioration of experimental murine colitis by the natural compound fraxinellone.

Qiang Xu, Gong Chen, Yan Shen, 2014, Toxicology and applied pharmacology.

Inhibition of SHP2 ameliorates psoriasis by decreasing TLR7 endosome localization

Qiang Xu, G. Feng, Yang Sun, 2020, medRxiv.

New opportunities and challenges of natural products research: When target identification meets single-cell multiomics

Qiang Xu, Yang Sun, Hongyue Ma, 2022, Acta pharmaceutica Sinica. B.

Si-Ni-San, a traditional Chinese prescription, and its active ingredient glycyrrhizin ameliorate experimental colitis through regulating cytokine balance.

Qiang Xu, Yan Shen, Yang Sun, 2009, International immunopharmacology.

Si‐Ni‐San, a traditional Chinese prescription, and its drug‐pairs suppress contact sensitivity in mice via inhibition of the activity of metalloproteinases and adhesion of T lymphocytes

Qiang Xu, Yang Sun, Ting Chen, 2003, The Journal of pharmacy and pharmacology.

Celastrol targets adenylyl cyclase-associated protein 1 to reduce macrophages-mediated inflammation and ameliorates high fat diet-induced metabolic syndrome in mice

Qiang Xu, Yang Sun, Ning Wan, 2020, Acta pharmaceutica Sinica. B.

A Novel Disease-Modifying Antirheumatic Drug, Iguratimod, Ameliorates Murine Arthritis by Blocking IL-17 Signaling, Distinct from Methotrexate and Leflunomide

Qiang Xu, C. Qian, Yanhong Gu, 2013, The Journal of Immunology.

Antifungal activity of MAF-1A peptide against Candida albicans

Qiang Xu, Hongling Li, Fangfang Hu, 2021, International Microbiology.

A new pharmacological effect of levornidazole: Inhibition of NLRP3 inflammasome activation.

Qiang Xu, Wei Chen, Yan Shen, 2015, Biochemical pharmacology.

Transmembrane-Bound IL-15–Promoted Epithelial-Mesenchymal Transition in Renal Cancer Cells Requires the Src-Dependent Akt/GSK-3β/β-Catenin Pathway

Qiang Xu, Xiaoxin Meng, Yanhong Gu, 2015, Neoplasia.

Libertellenone M, a diterpene derived from an endophytic fungus Phomopsis sp. S12, protects against DSS-induced colitis via inhibiting both nuclear translocation of NF-κB and NLRP3 inflammasome activation.

Qiang Xu, Yan Shen, Jian Gao, 2020, International immunopharmacology.

Immunomodulatory activity of the aqueous extract from rhizome of Smilax glabra in the later phase of adjuvant-induced arthritis in rats.

Qiang Xu, Jieyun Jiang, 2003, Journal of ethnopharmacology.

Targeting Peroxiredoxin 1 by a Curcumin Analogue, AI-44, Inhibits NLRP3 Inflammasome Activation and Attenuates Lipopolysaccharide-Induced Sepsis in Mice

Qiang Xu, Yang Sun, Wei Zheng, 2018, The Journal of Immunology.

Human TNF-alpha gene vaccination prevents collagen-induced arthritis in mice.

Qiang Xu, Yan Shen, Xuefeng Wu, 2007, International immunopharmacology.

Isomeranzin suppresses inflammation by inhibiting M1 macrophage polarization through the NF-κB and ERK pathway.

Qiang Xu, Yan Shen, Xuefeng Wu, 2016, International immunopharmacology.

Homeostatic properties of Lactobacillus jensenii engineered as a live vaginal anti-HIV microbicide

Qiang Xu, R. Fichorova, Hidemi S. Yamamoto, 2013, BMC Microbiology.

Advances in ameliorating inflammatory diseases and cancers by andrographolide: Pharmacokinetics, pharmacodynamics, and perspective

Qiang Xu, Yang Sun, Wenjie Guo, 2021, Medicinal research reviews.

Preclinical development of GR1501, a human monoclonal antibody that neutralizes interleukin-17A.

Qiang Xu, Yuan Gao, W. Jin, 2019, Biochemical and biophysical research communications.

Combination of apatinib with apo-IDO1 inhibitor for the treatment of colorectal cancer.

Qiang Xu, Wenjie Guo, Yi He, 2022, International immunopharmacology.

Obaculactone protects against bleomycin-induced pulmonary fibrosis in mice.

Qiang Xu, Yan Shen, Yang Sun, 2016, Toxicology and applied pharmacology.

Blockade of the interaction between Bcr-Abl and PTB1B by small molecule SBF-1 to overcome imatinib-resistance of chronic myeloid leukemia cells.

Qiang Xu, Wei Chen, Yan Shen, 2016, Cancer letters.

Inducible SHP‐2 activation confers resistance to imatinib in drug‐tolerant chronic myeloid leukemia cells

Qiang Xu, Yan Shen, Yang Sun, 2018, Toxicology and applied pharmacology.

Diptoindonesin G promotes ERK-mediated nuclear translocation of p-STAT1 (Ser727) and cell differentiation in AML cells

Qiang Xu, Yanhong Gu, Yan Shen, 2017, Cell Death & Disease.

Epigallocatechin-3-gallate sensitizes IFN-γ-stimulated CD4+ T cells to apoptosis via alternative activation of STAT1.

Qiang Xu, Yanhong Gu, Xuefeng Wu, 2014, International immunopharmacology.

Anti‐inflammatory actions of Caesalpinin M2 in experimental colitis as a selective glucocoricoid receptor modulator

Huiyuan Gao, Qiang Xu, Yan Shen, 2018, Biochemical pharmacology.

Pterostilbene prevents hepatocyte epithelial‐mesenchymal transition in fructose‐induced liver fibrosis through suppressing miR‐34a/Sirt1/p53 and TGF‐β1/Smads signalling

Qiang Xu, Jian-Mei Li, L. Kong, 2019, British journal of pharmacology.

Andrographolide sulfonate ameliorates lipopolysaccharide-induced acute lung injury in mice by down-regulating MAPK and NF-κB pathways

Qiang Xu, Yang Sun, Wenjie Guo, 2016, Acta pharmaceutica Sinica. B.

Andrographolide sulfonate ameliorates experimental colitis in mice by inhibiting Th1/Th17 response.

Qiang Xu, Yanhong Gu, Xuefeng Wu, 2014, International immunopharmacology.

Comparative genome mining and heterologous expression of an orphan NRPS gene cluster direct the production of ashimides† †Electronic supplementary information (ESI) available. CCDC 1861590. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c8sc05670f

Qiang Xu, Yang Sun, H. Ge, 2019, Chemical science.

Precursor-directed fungal generation of novel halogenated chaetoglobosins with more preferable immunosuppressive action.

Qiang Xu, Yan Shen, Zhi-kai Guo, 2011, Chemical communications.

cis-Khellactone Inhibited the Proinflammatory Macrophages via Promoting Autophagy to Ameliorate Imiquimod-Induced Psoriasis.

Qiang Xu, Pingping Song, Lingdong Kong, 2019, The Journal of investigative dermatology.

Nitric oxide inhibits T cell adhesion and migration by down-regulation of beta1-integrin expression in immunologically liver-injured mice.

Qiang Xu, Yang Sun, Feng Qian, 2006, International immunopharmacology.

Selective depletion of glycyrrhizin from Si-Ni-San, a traditional Chinese prescription, blocks its effect on contact sensitivity in mice and recovers adhesion and metalloproteinases production of T lymphocytes

Qiang Xu, Yang Sun, Li Zhang, 2005, International Immunopharmacology.

Fumigaclavine C ameliorates dextran sulfate sodium-induced murine experimental colitis via NLRP3 inflammasome inhibition.

Qiang Xu, Yang Sun, Wenjie Guo, 2015, Journal of pharmacological sciences.

(+)‐Borneol improves the efficacy of edaravone against DSS‐induced colitis by promoting M2 macrophages polarization via JAK2‐STAT3 signaling pathway

Qiang Xu, Yan Shen, Xuefeng Wu, 2017, International immunopharmacology.

Herpetol ameliorates allergic contact dermatitis through regulating T-lymphocytes.

Qiang Xu, Yang Sun, R. Tan, 2016, International immunopharmacology.

Neochromine S5 improves contact hypersensitivity through a selective effect on activated T lymphocytes.

Qiang Xu, Yan Shen, Xuefeng Wu, 2014, Biochemical pharmacology.

Saikosaponin a inhibits the proliferation and activation of T cells through cell cycle arrest and induction of apoptosis.

Qiang Xu, Yang Sun, Tian-Tian Cai, 2009, International immunopharmacology.

Self-renewal and Differentiation of Muscle Satellite Cells Are Regulated by the Fas-associated Death Domain*

Qiang Xu, Wei Cheng, Rong Zhang, 2013, The Journal of Biological Chemistry.

Targeting chondrocytes for arresting bony fusion in ankylosing spondylitis

Qiang Xu, G. Feng, Yang Sun, 2021, Nature Communications.

Iguratimod Synergizes with Methotrexate to Exert Anti-Inflammatory and Bone-Protective Effect and Block the Progression of Collagen-Induced Arthritis in Mices

Qiang Xu, 2014 .

Inhibition of Th1/Th17 responses via suppression of STAT1 and STAT3 activation contributes to the amelioration of murine experimental colitis by a natural flavonoid glucoside icariin.

Qiang Xu, C. Qian, Yang Sun, 2013, Biochemical pharmacology.

Qiang Xu, Yan Shen, Xin Li, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Targeting Sarcoplasmic/Endoplasmic Reticulum Ca2+-ATPase 2 by Curcumin Induces ER Stress-Associated Apoptosis for Treating Human Liposarcoma

Qiang Xu, R. Song, Lu Wang, 2011, Molecular Cancer Therapeutics.

A novel regulatory mechanism of naringenin through inhibition of T lymphocyte function in contact hypersensitivity suppression.

Qiang Xu, Feng Fang, Zhe Gao, 2010, Biochemical and biophysical research communications.

Tupistra chinensis extract attenuates murine fulminant hepatitis with multiple targets against activated T lymphocytes

Qiang Xu, Yan Shen, Xuefeng Wu, 2014, The Journal of pharmacy and pharmacology.

Mitochondria-Dependent Apoptosis of Con A-Activated T Lymphocytes Induced by Asiatic Acid for Preventing Murine Fulminant Hepatitis

Qiang Xu, C. Qian, Yan Shen, 2012, PloS one.

Selective triggering of apoptosis of concanavalin A-activated T cells by fraxinellone for the treatment of T-cell-dependent hepatitis in mice.

Yu Qin, Qiang Xu, Xuefeng Wu, 2009, Biochemical pharmacology.

Dregea volubilis Ameliorates Concanavalin A-Induced Liver Injury by Facilitating Apoptosis of Activated T Cells

Qiang Xu, Yan Shen, Xuefeng Wu, 2008, Experimental biology and medicine.

A novel model of acute liver injury in mice induced by T cell‐mediated immune response to lactosylated bovine serum albumin

Qiang Xu, Ling Xu, Yu Qin, 2006, Clinical and experimental immunology.

Inhibition of AIM2 inflammasome-mediated pyroptosis by Andrographolide contributes to amelioration of radiation-induced lung inflammation and fibrosis

Jian Sun, Qiang Xu, Xinchen Sun, 2019, Cell Death & Disease.

Aqueous extract from aerial parts of Artemisia vestita, a traditional Tibetan medicine, reduces contact sensitivity in mice by down-regulating the activation, adhesion and metalloproteinase production of T lymphocytes.

Qiang Xu, Yang Sun, Ju-le Wang, 2005, International immunopharmacology.

Synthesis and biological evaluation of unique stereodimers of sinomenine analogues as potential inhibitors of NO production.

Qiang Xu, Jian-Xin Li, Liping Feng, 2011, Bioorganic & medicinal chemistry.

MALT1 inhibitors prevent the development of DSS-induced experimental colitis in mice via inhibiting NF-κB and NLRP3 inflammasome activation

Qiang Xu, Yan Shen, Xuefeng Wu, 2016, Oncotarget.

SHP2-mediated mitophagy boosted by lovastatin in neuronal cells alleviates parkinsonism in mice

Qiang Xu, L. Ouyang, Yang Sun, 2021, Signal Transduction and Targeted Therapy.

Actinotetraoses A–H: Tetrasaccharide Derivatives from a Grasshopper-Associated Amycolatopsis sp. HCa1

Qiang Xu, Yan Shen, Zhi-kai Guo, 2012, Planta Medica.

Apo-Form Selective Inhibition of IDO for Tumor Immunotherapy

Qiang Xu, Wenjie Guo, Shushan Ge, 2022, The Journal of Immunology.

Role of Intestinal Microbes in Chronic Liver Diseases

Qiang Xu, Kangkang Luo, Xudong Wu, 2022, International journal of molecular sciences.

Mechanisms of hepatoprotection of Terminalia catappa L. extract on D-Galactosamine-induced liver damage.

Qiang Xu, Jing Gao, Xin-hui Tang, 2004, The American journal of Chinese medicine.

Meisoindigo attenuates dextran sulfate sodium-induced experimental colitis via its inhibition of TAK1 in macrophages.

Qiang Xu, Jingcai Cheng, Yan Shen, 2021, International immunopharmacology.

SH2 Domain–Containing Phosphatase 2 Inhibition Attenuates Osteoarthritis by Maintaining Homeostasis of Cartilage Metabolism via the Docking Protein 1/Uridine Phosphorylase 1/Uridine Cascade

D. Shi, Qiang Xu, Yang Sun, 2022 .

Synthesis and immunosuppressive activity of L-rhamnopyranosyl flavonoids.

Qiang Xu, Yang Sun, Zijian Guo, 2006, Organic & biomolecular chemistry.

Ethanol extract from Artemisia vestita, a traditional Tibetan medicine, exerts anti-sepsis action through down-regulating the MAPK and NF-kappaB pathways.

Qiang Xu, Yang Sun, Z. Hua, 2006, International journal of molecular medicine.

Bulk Erosion Degradation Mechanism for Poly(1,8-octanediol-co-citrate) Elastomer: An In Vivo and In Vitro Investigation.

Qiang Xu, Liangliang Lu, X. Jia, 2022, Biomacromolecules.

Effect of Naringin on Monosodium Iodoacetate-Induced Osteoarthritis Pain in Rats

Qiang Xu, Zuofu Zhang, Weixue Sun, 2017, Medical science monitor : international medical journal of experimental and clinical research.

Fumigaclavine C, an fungal metabolite, improves experimental colitis in mice via downregulating Th1 cytokine production and matrix metalloproteinase activity.

Qiang Xu, M. Fei, Xuefeng Wu, 2005, International immunopharmacology.

Dissection of the role of paeoniflorin in the traditional Chinese medicinal formula Si-Ni-San against contact dermatitis in mice.

Qiang Xu, Yang Sun, Yi-Ying Dong, 2009, Life sciences.

Ultrasound-promoted synthesis and immunosuppressive activity of novel quinazoline derivatives

Qiang Xu, Jian-Xin Li, Dan Zhao, 2012, Molecular Diversity.

Synthesis and evaluation of a novel series of quinoline derivatives with immunosuppressive activity.

Qiang Xu, Jian-Xin Li, Gong Chen, 2009, Bioorganic & medicinal chemistry.

Suppression of adenosine monophosphate-activated protein kinase selectively triggers apoptosis in activated T cells and ameliorates immune diseases.

Qiang Xu, Xuefeng Wu, Yang Sun, 2017, Biochemical and biophysical research communications.

SBF-1 inhibits contact hypersensitivity in mice through down-regulation of T-cell-mediated responses

Qiang Xu, Lijun Sun, Xianying Fang, 2019, BMC Pharmacology and Toxicology.

Vaticaffinol, a resveratrol tetramer, exerts more preferable immunosuppressive activity than its precursor in vitro and in vivo through multiple aspects against activated T lymphocytes.

Qiang Xu, Yan Shen, Xuefeng Wu, 2013, Toxicology and applied pharmacology.

Quercetin induced NUPR1-dependent autophagic cell death by disturbing reactive oxygen species homeostasis in osteosarcoma cells

Qiang Xu, Xiping Zhang, Jian Chen, 2020, Journal of clinical biochemistry and nutrition.

Inhibitory effects of ethanol extract from Radix Ophiopogon japonicus on venous thrombosis linked with its endothelium-protective and anti-adhesive activities.

Qiang Xu, J. Kou, Boyang Yu, 2005, Vascular pharmacology.

Ruscogenin glycoside (Lm‐3) isolated from Liriope muscari inhibits lymphocyte adhesion to extracellular matrix

Qiang Xu, Boyang Yu, Ting Chen, 2002, The Journal of pharmacy and pharmacology.

Anti-inflammatory activities of aqueous extract from Radix Ophiopogon japonicus and its two constituents.

Qiang Xu, Yang Sun, Wei Zheng, 2005, Biological & pharmaceutical bulletin.

Mitochondria-dependent apoptosis of activated T lymphocytes induced by astin C, a plant cyclopeptide, for preventing murine experimental colitis.

Qiang Xu, G. Zeng, Yan Shen, 2011, Biochemical pharmacology.

Ruscogenin glycoside (Lm‐3) isolated from Liriope muscari improves liver injury by dysfunctioning liver‐infiltrating lymphocytes

Qiang Xu, Jingsong Cao, Boyang Yu, 2001, The Journal of pharmacy and pharmacology.

Immunosuppressive polyketides from mantis-associated Daldinia eschscholzii.

Qiang Xu, Nan Jiang, Jing Ma, 2011, Journal of the American Chemical Society.

A novel benzo[d]imidazole derivate prevents the development of dextran sulfate sodium-induced murine experimental colitis via inhibition of NLRP3 inflammasome.

Qiang Xu, Yanhong Gu, Yan Shen, 2013, Biochemical pharmacology.

Seselin ameliorates inflammation via targeting Jak2 to suppress the proinflammatory phenotype of macrophages

Qiang Xu, Yan Shen, Xuefeng Wu, 2018, British journal of pharmacology.

Synthesis and biological evaluation of novel sinomenine derivatives as anti-inflammatory agents.

Qiang Xu, Jian-Xin Li, Yang Sun, 2012, European journal of medicinal chemistry.

Synthesis of a novel series of diphenolic chromone derivatives as inhibitors of NO production in LPS-activated RAW264.7 macrophages.

Qiang Xu, Jian-Xin Li, Jian-wei Zhao, 2010, Bioorganic & medicinal chemistry.

Immunosuppressive Diterpenes from Phomopsis sp. S12

Qiang Xu, Yan Shen, Wei Wei, 2014 .

Immunosuppressive Diterpenes from Phomopsis sp. S12.

Qiang Xu, Yan Shen, Wei Wei, 2015 .

Erlotinib promotes endoplasmic reticulum stress-mediated injury in the intestinal epithelium.

Qiang Xu, Xianying Fang, Yanhong Gu, 2014, Toxicology and applied pharmacology.

One novel quinoxaline derivative as a potent human cyclophilin A inhibitor shows highly inhibitory activity against mouse spleen cell proliferation

Li Zhang, Yu Qin, Jingkang Shen, 2006, Bioorganic & Medicinal Chemistry.

Mechanism underlying mitochondrial protection of asiatic acid against hepatotoxicity in mice

Qiang Xu, Jing Gao, Lizhi Xu, 2006, The Journal of pharmacy and pharmacology.

Anti-inflammatory and immunosuppressive effect of flavones isolated from Artemisia vestita.

Qiang Xu, Yang Sun, Ting Chen, 2008, Journal of ethnopharmacology.

Effective protection of Terminalia catappa L. leaves from damage induced by carbon tetrachloride in liver mitochondria.

Qiang Xu, Z. Qian, Jing Gao, 2006, The Journal of nutritional biochemistry.

Astilbin inhibits the adhesion of T lymphocytes via decreasing TNF-alpha and its associated MMP-9 activity and CD44 expression.

Qiang Xu, Jun Wang, H. Yi, 2008, International immunopharmacology.

Curcumin inhibits metastasis in human papillary thyroid carcinoma BCPAP cells via down-regulation of the TGF-β/Smad2/3 signaling pathway.

Qiang Xu, Yang Sun, Huixin Yu, 2016, Experimental cell research.

Induction of ROS-independent DNA damage by curcumin leads to G2/M cell cycle arrest and apoptosis in human papillary thyroid carcinoma BCPAP cells.

Qiang Xu, Yang Sun, Huixin Yu, 2016, Food & function.

Small molecule RL71 targets SERCA2 at a novel site in the treatment of human colorectal cancer

Qiang Xu, Yan Shen, Xuefeng Wu, 2015, Oncotarget.

Andrographolide ameliorates OVA-induced lung injury in mice by suppressing ROS-mediated NF-κB signaling and NLRP3 inflammasome activation

Qiang Xu, Yang Sun, Wenjie Guo, 2016, Oncotarget.

Simultaneous quantification of five major bioactive flavonoids in Rhizoma smilacis glabrae by high-performance liquid chromatography.

Qiang Xu, H. Yi, Ting Chen, 2007, Journal of pharmaceutical and biomedical analysis.

Andrographolide reversed 5-FU resistance in human colorectal cancer by elevating BAX expression.

Qiang Xu, Yanhong Gu, Yang Sun, 2016, Biochemical pharmacology.

Small molecule-driven mitophagy-mediated NLRP3 inflammasome inhibition is responsible for the prevention of colitis-associated cancer

Qiang Xu, Yanhong Gu, Yan Shen, 2014, Autophagy.

Water-soluble andrographolide sulfonate exerts anti-sepsis action in mice through down-regulating p38 MAPK, STAT3 and NF-κB pathways.

Qiang Xu, C. Qian, Gong Chen, 2012, International immunopharmacology.

Hepatoprotective activity of Terminalia catappa L. leaves and its two triterpenoids

Qiang Xu, Jing Gao, Huan Dou, 2004, The Journal of pharmacy and pharmacology.

Δ10(E)-Sphingolipid Desaturase Involved in Fusaruside Mycosynthesis and Stress Adaptation in Fusarium graminearum

Qiang Xu, R. Tan, Yuan-ru-hua Tian, 2015, Scientific Reports.

Permeation of astilbin and taxifolin in Caco-2 cell and their effects on the P-gp.

Qiang Xu, S. Zeng, Ting Liu, 2009, International journal of pharmaceutics.

Landscape of SARS-CoV-2 spike protein-interacting cells in human tissues

Qiang Xu, Zi-feng Yang, Peipei Xu, 2021, International Immunopharmacology.

Genome Mining and Comparative Biosynthesis of Meroterpenoids from Two Phylogenetically Distinct Fungi.

Qiang Xu, H. Ge, R. Tan, 2018, Angewandte Chemie.

Discovery and biosynthesis of bosamycins from Streptomyces sp. 120454†

Qiang Xu, Yang Sun, H. Ge, 2020, Chemical science.

Discovery of imidazoleisoindole derivatives as potent IDO1 inhibitors: Design, synthesis, biological evaluation and computational studies.

Qiang Xu, Wenjie Guo, F. Wang, 2017, European journal of medicinal chemistry.

A novel combination of astilbin and low‐dose methotrexate respectively targeting A2AAR and its ligand adenosine for the treatment of collagen‐induced arthritis

Qiang Xu, Yan Shen, Xuefeng Wu, 2018, Biochemical pharmacology.

Citrus fruits are rich in flavonoids for immunoregulation and potential targeting ACE2

Qiang Xu, Ming Li, Wei-wei Zheng, 2020, Natural products and bioprospecting.

Allosteric inhibition reveals SHP2-mediated tumor immunosuppression in colon cancer by single-cell transcriptomics

Qiang Xu, Yang Sun, Yuxian Shen, 2021, Acta pharmaceutica Sinica. B.

Microbial transformation of three bufadienolides by Nocardia sp. and some insight for the cytotoxic structure-activity relationship (SAR).

Qiang Xu, Yang Sun, Ji-Hua Liu, 2007, Bioorganic & medicinal chemistry letters.

Microbial Transformation of Three Bufadienolides by Nocardia sp. and Some Insight for the Cytotoxic Structure—Activity Relationship (SAR).

Qiang Xu, Yang Sun, Ji-Hua Liu, 2008 .

Pictet–Spengler reaction-based biosynthetic machinery in fungi

Qiang Xu, S. Ng,, Nan Jiang, 2014, Proceedings of the National Academy of Sciences.

Naphthol radical couplings determine structural features and enantiomeric excess of dalesconols in Daldinia eschscholzii

Qiang Xu, Nan Jiang, H. Ge, 2012, Nature Communications.

Andrographolide sulfonate ameliorates chronic colitis induced by TNBS in mice via decreasing inflammation and fibrosis.

Qiang Xu, Wenjie Guo, Wen Liu, 2020, International immunopharmacology.

Triggering a switch from basal- to luminal-like breast cancer subtype by the small-molecule diptoindonesin G via induction of GABARAPL1

Qiang Xu, Yan Shen, Xuefeng Wu, 2020, Cell Death & Disease.

Asiatic acid ameliorates dextran sulfate sodium-induced murine experimental colitis via suppressing mitochondria-mediated NLRP3 inflammasome activation.

Qiang Xu, Yang Sun, Wenjie Guo, 2015, International immunopharmacology.

Activating AMPK to Restore Tight Junction Assembly in Intestinal Epithelium and to Attenuate Experimental Colitis by Metformin

Qiang Xu, Yan Shen, Xuefeng Wu, 2018, Front. Pharmacol..

A reference single-cell regulomic and transcriptomic map of cynomolgus monkeys

Qiang Xu, Yan Ding, Yang Sun, 2022, Nature Communications.

An Anticancer Effect of Curcumin Mediated by Down-Regulating Phosphatase of Regenerating Liver-3 Expression on Highly Metastatic Melanoma Cells

Qiang Xu, R. Song, Lu Wang, 2009, Molecular Pharmacology.

Tyrosine phosphatase SHP2 negatively regulates NLRP3 inflammasome activation via ANT1-dependent mitochondrial homeostasis

Qiang Xu, G. Feng, Yanhong Gu, 2017, Nature Communications.

Amycolamycins A and B, Two Enediyne-Derived Compounds from a Locust-Associated Actinomycete.

Qiang Xu, Yang Sun, Zhi-kai Guo, 2017, Organic letters.

Blocking initial infiltration of pioneer CD8+ T‐cells into the CNS via inhibition of SHP‐2 ameliorates experimental autoimmune encephalomyelitis in mice

Qiang Xu, Yan Shen, Yang Sun, 2014, British journal of pharmacology.

Characterization of the transcriptional response of Candida parapsilosis to the antifungal peptide MAF-1A

Qiang Xu, Fuxun Yu, Wei Li, 2020, PeerJ.

Exosomal Transfer Of Cisplatin-Induced miR-425-3p Confers Cisplatin Resistance In NSCLC Through Activating Autophagy

Qiang Xu, Yan Shen, Y. Shu, 2019, International journal of nanomedicine.

Cerebroside D, a glycoceramide compound, improves experimental colitis in mice with multiple targets against activated T lymphocytes.

Qiang Xu, Yanhong Gu, Yan Shen, 2012, Toxicology and applied pharmacology.

Cirsilineol inhibits proliferation of cancer cells by inducing apoptosis via mitochondrial pathway

Qiang Xu, Yang Sun, Ting Chen, 2008 .

Cirsilineol inhibits proliferation of cancer cells by inducing apoptosis via mitochondrial pathway.

Qiang Xu, Yang Sun, Ting Chen, 2008, The Journal of pharmacy and pharmacology.

Axitinib, a selective inhibitor of vascular endothelial growth factor receptor, exerts an anticancer effect in melanoma through promoting antitumor immunity

Qiang Xu, Xianying Fang, Wei Chen, 2014, Anti-cancer drugs.

SBF-1, a synthetic steroidal glycoside, inhibits melanoma growth and metastasis through blocking interaction between PDK1 and AKT3.

Qiang Xu, Xianying Fang, Wei Chen, 2012, Biochemical pharmacology.

Allosteric inhibition of SHP2 uncovers aberrant TLR7 trafficking in aggravating psoriasis

Qiang Xu, Yang Sun, Wenjie Guo, 2021, EMBO molecular medicine.

PRL-3 siRNA Inhibits the Metastasis of B16-BL6 Mouse Melanoma Cells In Vitro and In Vivo

Qiang Xu, R. Song, Z. Hua, 2007, Molecular medicine.

Typically inhibiting USP14 promotes autophagy in M1-like macrophages and alleviates CLP-induced sepsis

Qiang Xu, Ronghui Du, G. Liang, 2020, Cell Death & Disease.

Berberine inhibits palmitate-induced NLRP3 inflammasome activation by triggering autophagy in macrophages: A new mechanism linking berberine to insulin resistance improvement.

Qiang Xu, Yan Shen, Xuefeng Wu, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Pentamethoxyflavanone regulates macrophage polarization and ameliorates sepsis in mice.

Qiang Xu, Yan Shen, Yang Sun, 2014, Biochemical pharmacology.

Loss of SHP-2 activity in CD4+ T cells promotes melanoma progression and metastasis

Qiang Xu, Lu Wang, Yanhong Gu, 2013, Scientific Reports.

Targeting HIBCH to reprogram valine metabolism for the treatment of colorectal cancer

Qiang Xu, Lijun Sun, Ying Wang, 2019, Cell Death & Disease.

Jaceosidin Induces Apoptosis in Human Ovary Cancer Cells through Mitochondrial Pathway

Qiang Xu, Ting Chen, X. Sheng, 2008, Journal of biomedicine & biotechnology.

Erlotinib inhibits T-cell-mediated immune response via down-regulation of the c-Raf/ERK cascade and Akt signaling pathway.

Qiang Xu, Yanhong Gu, Yang Sun, 2011, Toxicology and applied pharmacology.

The deubiquitinase USP6 affects memory and synaptic plasticity through modulating NMDA receptor stability

Qiang Xu, Huaxi Xu, Timothy Y. Huang, 2019, PLoS biology.

Dietary fructose-induced gut dysbiosis promotes mouse hippocampal neuroinflammation: a benefit of short-chain fatty acids

Qiang Xu, Jian-Mei Li, Rong Yu, 2019, Microbiome.

Involvement of Na+, K+-ATPase and its inhibitors in HuR-mediated cytokine mRNA stabilization in lung epithelial cells

Qiang Xu, Wei Cheng, Wei Chen, 2010, Cellular and Molecular Life Sciences.

Engineering of Lactobacillus jensenii To Secrete RANTES and a CCR5 Antagonist Analogue as Live HIV-1 Blockers

Qiang Xu, A. Bachi, P. Lusso, 2010, Antimicrobial Agents and Chemotherapy.

Engineered Vaginal Lactobacillus Strain for Mucosal Delivery of the Human Immunodeficiency Virus Inhibitor Cyanovirin-N

Yang Liu, Qiang Xu, Xiaowen Liu, 2006, Antimicrobial Agents and Chemotherapy.

Inhibition of HIV infectivity by a natural human isolate of Lactobacillus jensenii engineered to express functional two-domain CD4

D. Ho, Qiang Xu, G. Schoolnik, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Andrographolide potentiates PD-1 blockade immunotherapy by inhibiting COX2-mediated PGE2 release.

Qiang Xu, Yang Sun, Lixuan Liu, 2020, International immunopharmacology.

Targeting the PDGF-B/PDGFR-β Interface with Destruxin A5 to Selectively Block PDGF-BB/PDGFR-ββ Signaling and Attenuate Liver Fibrosis

Qiang Xu, Wei Chen, Yan Shen, 2016, EBioMedicine.

DNA damage repair promotion in colonic epithelial cells by andrographolide downregulated cGAS‒STING pathway activation and contributed to the relief of CPT-11-induced intestinal mucositis

Qiang Xu, J. Wu, Yanhong Gu, 2021, Acta pharmaceutica Sinica. B.

Improvement of magnesium isoglycyrrhizinate on DSS-induced acute and chronic colitis.

Qiang Xu, Wenjie Guo, Lingdong Kong, 2020, International immunopharmacology.

Axitinib augments antitumor activity in renal cell carcinoma via STAT3-dependent reversal of myeloid-derived suppressor cell accumulation.

Qiang Xu, Yanhong Gu, Yang Sun, 2014, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Single-cell transcriptomics reveals the natural product Shi-Bi-Man promotes hair regeneration by activating the FGF pathway in dermal papilla cells.

Qiang Xu, Yang Sun, Chenyang Zhang, 2022, Phytomedicine : international journal of phytotherapy and phytopharmacology.

MLN4924 neddylation inhibitor promotes cell death in paclitaxel-resistant human lung adenocarcinoma cells.

Qiang Xu, Wei Cheng, Yupeng Wang, 2017, Oncology letters.

Therapeutic Potential of Apatinib Against Colorectal Cancer by Inhibiting VEGFR2-Mediated Angiogenesis and β-Catenin Signaling

Qiang Xu, Yanhong Gu, Wenjie Guo, 2020, OncoTargets and therapy.

SHP2-Mediated Inhibition of DNA Repair Contributes to cGAS–STING Activation and Chemotherapeutic Sensitivity in Colon Cancer

Qiang Xu, J. Wu, Yanhong Gu, 2021, Cancer Research.

Intracellular CYTL1, a novel tumor suppressor, stabilizes NDUFV1 to inhibit metabolic reprogramming in breast cancer

Qiang Xu, Yan Shen, Xin Li, 2022, Signal Transduction and Targeted Therapy.

Purine metabolites promote ectopic new bone formation in ankylosing spondylitis.

Qiang Xu, Yang Sun, Z. Ouyang, 2023, International immunopharmacology.

Curcumin and allopurinol ameliorate fructose‐induced hepatic inflammation in rats via miR‐200a‐mediated TXNIP/NLRP3 inflammasome inhibition

Qiang Xu, L. Kong, Ying Pan, 2018, Pharmacological research.

SH2 Domain–Containing Phosphatase 2 Inhibition Attenuates Osteoarthritis by Maintaining Homeostasis of Cartilage Metabolism via the Docking Protein 1/Uridine Phosphorylase 1/Uridine Cascade

D. Shi, Qiang Xu, Yang Sun, 2021, Arthritis & rheumatology.

Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels

Qiang Xu, G. Feng, Yang Sun, 2020, The Journal of Biological Chemistry.

Inhibition of autophagy by andrographolide resensitizes cisplatin-resistant non-small cell lung carcinoma cells via activation of the Akt/mTOR pathway.

Qiang Xu, Yan Shen, Yang Sun, 2016, Toxicology and applied pharmacology.

Combination of Fruquintinib and Anti–PD-1 for the Treatment of Colorectal Cancer

Qiang Xu, Yanhong Gu, Yang Sun, 2020, The Journal of Immunology.

Design, Synthesis, and Evaluation of o-(Biphenyl-3-ylmethoxy)nitrophenyl Derivatives as PD-1/PD-L1 Inhibitors with Potent Anticancer Efficacy In Vivo.

Qiang Xu, Wenjie Guo, Yuezhen Li, 2021, Journal of medicinal chemistry.

Discovery of secondary sulphonamides as IDO1 inhibitors with potent antitumour effects in vivo

Qiang Xu, Wenjie Guo, Shushan Ge, 2020, Journal of enzyme inhibition and medicinal chemistry.

Genetically encoded red fluorescent copper(I) sensors for cellular copper(I) imaging.

Qiang Xu, Yan Shen, Yi Cao, 2014, Biochemical and biophysical research communications.

Obaculactone exerts a novel ameliorating effect on contact dermatitis through regulating T lymphocyte.

Qiang Xu, Yan Shen, Yang Sun, 2015, International immunopharmacology.

IgG antibody titers against SARS-CoV-2 nucleocapsid protein correlate with the severity of COVID-19 patients

Qiang Xu, Fuxun Yu, Y. Zha, 2021, BMC microbiology.

Carnosic acid enhances the anti-lung cancer effect of cisplatin by inhibiting myeloid-derived suppressor cells.

Qiang Xu, Yue Hu, Wen Liu, 2018, Chinese journal of natural medicines.

Loss of periplakin expression is associated with the tumorigenesis of colorectal carcinoma.

Qiang Xu, Yanhong Gu, Yang Sun, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

A fumigaclavine C isostere alleviates Th1‐mediated experimental colitis via competing with IFN‐&ggr; for binding to IFN‐&ggr; receptor 1

Qiang Xu, Yanhong Gu, Yang Sun, 2017, Biochemical pharmacology.

Immunosuppressive resveratrol aneuploids from Hopea chinensis.

Qiang Xu, Yan Shen, Jing Ma, 2010, Chemistry.

Hepatoprotection of oleanolic acid is related to its inhibition on mitochondrial permeability transition.

Qiang Xu, Jing Gao, Xin-hui Tang, 2005, The American journal of Chinese medicine.

CUG-binding protein 1 regulates HSC activation and liver fibrogenesis

Qiang Xu, Beicheng Sun, Xuefeng Wu, 2016, Nature Communications.

Magnesium isoglycyrrhizinate ameliorates high fructose-induced liver fibrosis in rat by increasing miR-375-3p to suppress JAK2/STAT3 pathway and TGF-β1/Smad signaling

Qiang Xu, Shui-juan Wang, L. Kong, 2018, Acta Pharmacologica Sinica.

Interaction between integrin alpha(5) and fibronectin is required for metastasis of B16F10 melanoma cells.

Qiang Xu, Xuefeng Wu, Feng Qian, 2005, Biochemical and biophysical research communications.

An Anticancer Effect of Curcumin Mediated by Down-regulating PRL-3 Expression on Highly Metastatic Melanoma Cells

Qiang Xu, R. Song, Lu Wang, 2009 .

5, 7, 2', 4', 5'-Pentamethoxyflavanone regulates M1/M2 macrophage phenotype and protects the septic mice.

Qiang Xu, L. Kong, Wei Huang, 2019, Chinese journal of natural medicines.

PRL-3 Promotes the Malignant Progression of Melanoma via Triggering Dephosphorylation and Cytoplasmic Localization of NHERF1.

Qiang Xu, Xianying Fang, Wei Chen, 2015, The Journal of investigative dermatology.

Trichomide A, a natural cyclodepsipeptide, exerts immunosuppressive activity against activated T lymphocytes by upregulating SHP2 activation to overcome contact dermatitis.

Qiang Xu, Wei Chen, Yan Shen, 2014, The Journal of investigative dermatology.

Andrographolide alleviates parkinsonism in MPTP-PD mice via targeting DRP1-mediated mitochondrial fission.

Qiang Xu, Z. Qin, Yang Sun, 2019, British journal of pharmacology.

Timp3 loss accelerates tumour invasion and increases prostate inflammation in a mouse model of prostate cancer

C. McKerlie, Qiang Xu, P. Waterhouse, 2015, The Prostate.

Apatinib suppresses tumor progression and enhances cisplatin sensitivity in esophageal cancer via the Akt/β-catenin pathway

Qiang Xu, J. Wu, Yanhong Gu, 2020, Cancer Cell International.

Workshop 26Immunological mechanisms of antitumor activity of some kinds of Chinese herbs

Qiang Xu, A. Koda, I. Nishioka, 1988 .

Andrographolide sulfonate improves Alzheimer-associated phenotypes and mitochondrial dysfunction in APP/PS1 transgenic mice.

Qiang Xu, Yang Sun, Wenjie Guo, 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Two mouse mutations mapped to chromosome 11 with differing morphologies but similar progressive inflammatory alopecia

A. Flenniken, C. McKerlie, J. Rossant, 2005, Experimental dermatology.

Two mouse mutations mapped to chromosome 11 with differing morphologies but similar progressive inflammatory alopecia.

A. Flenniken, C. McKerlie, K. Fleming, 2005 .

Jaceosidin inhibits contact hypersensitivity in mice via down-regulating IFN-γ/STAT1/T-bet signaling in T cells.

Qiang Xu, Yan Shen, Yang Sun, 2011, European journal of pharmacology.

Fraxinellone alleviates kidney fibrosis by inhibiting CUG-binding protein 1-mediated fibroblast activation.

Qiang Xu, Lingdong Kong, Shenglan Wang, 2021, Toxicology and applied pharmacology.

A Low-Producing Haplotype of Interleukin-6 Disrupting CTCF Binding Is Protective against Severe COVID-19

Ying Sun, Qiang Xu, Fuxun Yu, 2021, mBio.

Spirodalesol, an NLRP3 Inflammasome Activation Inhibitor.

Qiang Xu, Nan Jiang, R. Tan, 2016, Organic letters.

Small molecule targeting CELF1 RNA-binding activity to control HSC activation and liver fibrosis

Qiang Xu, B. Tang, Yan Ye, 2022, Nucleic acids research.

Microfluidics assisted synthesis and bioevaluation of sinomenine derivatives as antiinflammatory agents.

Qiang Xu, Jian-Xin Li, P. Teng, 2013, European journal of medicinal chemistry.

Rational design, synthesis and biological evaluation of dual PARP-1/2 and TNKS1/2 inhibitors for cancer therapy.

Qiang Xu, Qihua Zhu, Huanhuan Wu, 2022, European journal of medicinal chemistry.

Alleviating effects of si-ni-san, a traditional Chinese prescription, on experimental liver injury and its mechanisms.

Qiang Xu, Chunxiang Zhou, Jieyun Jiang, 2003, Biological & pharmaceutical bulletin.

A novel role of alkaline phosphatase in protection from immunological liver injury in mice.

Qiang Xu, Zhaohua Lu, Xianming Zhang, 2002, Liver.

Apoptosis of murine melanoma B16-BL6 cells induced by quercetin targeting mitochondria, inhibiting expression of PKC-α and translocating PKC-δ

Qiang Xu, Xianming Zhang, Jia Chen, 2005, Cancer Chemotherapy and Pharmacology.

Small-molecule RL71-triggered excessive autophagic cell death as a potential therapeutic strategy in triple-negative breast cancer

Qiang Xu, Yan Shen, Yang Sun, 2017, Cell Death & Disease.

Xiao-Ai-Ping, a TCM Injection, Enhances the Antigrowth Effects of Cisplatin on Lewis Lung Cancer Cells through Promoting the Infiltration and Function of CD8+ T Lymphocytes

Qiang Xu, Qi Zhang, Lu Wang, 2013, Evidence-based complementary and alternative medicine : eCAM.

Tyrosine phosphatase SHP2 negatively regulates NLRP3 inflammasome activation via ANT1-dependent mitochondrial homeostasis

Qiang Xu, G. Feng, Yanhong Gu, 2017, Nature Communications.

Andrographolide alleviates imiquimod-induced psoriasis in mice via inducing autophagic proteolysis of MyD88.

Qiang Xu, Yang Sun, Tao Tan, 2016, Biochemical pharmacology.

Prognostic Role of Circulating Exosomal miR-425-3p for the Response of NSCLC to Platinum-Based Chemotherapy

Qiang Xu, Yan Shen, Y. Shu, 2018, Cancer Epidemiology, Biomarkers & Prevention.

Novel role of Sarco/endoplasmic reticulum calcium ATPase 2 in development of colorectal cancer and its regulation by F36, a curcumin analog.

Qiang Xu, Yanhong Gu, Yan Shen, 2014, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

VEGF Promotes the Transcription of the Human PRL-3 Gene in HUVEC through Transcription Factor MEF2C

Qiang Xu, Gong Chen, Lu Wang, 2011, PloS one.

Apatinib enhanced anti-PD-1 therapy for colon cancer in mice via promoting PD-L1 expression.

Qiang Xu, Yanhong Gu, Yang Sun, 2020, International immunopharmacology.

Aqueous extract from rhizoma notopterygii reduces contact sensitivity by inhibiting lymphocyte migration via down-regulating metalloproteinase activity.

Qiang Xu, Yeping Sun, 2002, Pharmacological research.

A plant‐derived glucocorticoid receptor modulator with potency to attenuate the side effects of glucocorticoid therapy

Qiang Xu, Yan Shen, Bo Liu, 2022, British journal of pharmacology.

The double‐edged role of neutrophil heterogeneity in inflammatory diseases and cancers

Qiang Xu, Yang Sun, Xinran Cao, 2023, MedComm.

Mitochondrial folate metabolism–mediated α-linolenic acid exhaustion masks liver fibrosis resolution

Qiang Xu, Xueqing Sun, Bingfeng Zheng, 2023, The Journal of biological chemistry.

Sorafenib induces apoptosis in HL60 cells by inhibiting Src kinase-mediated STAT3 phosphorylation

Qiang Xu, Yanhong Gu, Yan Shen, 2011, Anti-cancer drugs.

Targeting the PTP1B‐Bcr‐Abl1 interaction for the degradation of T315I mutant Bcr‐Abl1 in chronic myeloid leukemia

Qiang Xu, Yan Shen, Jian Gao, 2022, Cancer science.

An autonomous activation of interleukin-17 receptor signaling sustains inflammation and promotes disease progression.

Qiang Xu, Yang Sun, Yaqi Yang, 2023, Immunity.

Small molecule‐mediated upregulation of CCR7 ameliorates murine experimental autoimmune encephalomyelitis by accelerating T‐cell homing

Qiang Xu, Yan Shen, R. Tan, 2017, International immunopharmacology.

Synthesis and biological evaluation of unique stereodimers of sinomenine analogues as potential inhibitors of NO production.

Qiang Xu, Jian-Xin Li, Liping Feng, 2011, Bioorganic & medicinal chemistry.

Preferential cytotoxicity of bortezomib toward highly malignant human liposarcoma cells via suppression of MDR1 expression and function.

Qiang Xu, Lu Wang, Yanhong Gu, 2015, Toxicology and applied pharmacology.

Single-cell analyses reveal cannabidiol rewires tumor microenvironment via inhibiting alternative activation of macrophage and synergizes with anti-PD-1 in colon cancer

Yi Wang, Qiang Xu, Yanhong Gu, 2023, Journal of pharmaceutical analysis.

Quantitative determination of astilbin in rabbit plasma by liquid chromatography.

Qiang Xu, Ting-Hsing Chen, Jianming Guo, 2004, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Fumigaclavine C improves concanavalin A‐induced liver injury in mice mainly via inhibiting TNF‐α production and lymphocyte adhesion to extracellular matrices

Qiang Xu, R. Tan, Jun Wang, 2004, The Journal of pharmacy and pharmacology.

Genome Mining and Comparative Biosynthesis of Meroterpenoids from Two Phylogenetically Distinct Fungi

Qiang Xu, H. Ge, Wen-jie Guo, 2018, Angewandte Chemie.

Indolocarbazole alkaloid Loonamycin A inhibits triple-negative breast cancer cell stemness and Notch signalling.

Qiang Xu, Yan Shen, Wenwen Xue, 2023, The Journal of pharmacy and pharmacology.

Natural compound fraxinellone ameliorates intestinal fibrosis in mice via direct intervention of HSP47-collagen interaction in the epithelium.

Qiang Xu, Yan Shen, Xuefeng Wu, 2023, Acta pharmacologica Sinica.

Direct Inhibition of GSDMD by PEITC Reduces Hepatocyte Pyroptosis and Alleviates Acute Liver Injury in Mice

Qiang Xu, Yan Shen, Ronghui Du, 2022, Frontiers in Immunology.

Magnesium isoglycyrrhizinate ameliorates high fructose-induced liver fibrosis in rat by increasing miR-375-3p to suppress JAK2/STAT3 pathway and TGF-β1/Smad signaling

Qiang Xu, Shui-juan Wang, L. Kong, 2018, Acta Pharmacologica Sinica.

Targeting Sarcoplasmic/Endoplasmic Reticulum Ca2+-ATPase 2 by Curcumin Induces ER Stress-Associated Apoptosis for Treating Human Liposarcoma

Qiang Xu, R. Song, Lu Wang, 2011, Molecular Cancer Therapeutics.

Curcumin inhibits metastasis in human papillary thyroid carcinoma BCPAP cells via down-regulation of the TGF-β/Smad2/3 signaling pathway.

Qiang Xu, Yang Sun, Huixin Yu, 2016, Experimental cell research.

Tamsulosin combined with levofloxacin can effectively improve the clinical symptoms and reduce inflammation in CP/CPPS patients

Qiang Xu, Y. Ye, M. Wan, 2021 .

Erlotinib inhibits T-cell-mediated immune response via down-regulation of the c-Raf/ERK cascade and Akt signaling pathway.

Qiang Xu, Yanhong Gu, Yang Sun, 2011, Toxicology and applied pharmacology.

CD4 T lymphocytes cause hepatocyte apoptosis by releasing Th1 cytokines in cellular immunological liver injury

Qiang Xu, X.-C. Chen, Q. Xu, 2002, Inflammation Research.

Sequestration of Guest Intermediates by Dalesconol Bioassembly Lines in Daldinia eschscholzii.

Qiang Xu, Nan Jiang, R. Tan, 2017, Organic letters.

Isomeranzin suppresses inflammation by inhibiting M1 macrophage polarization through the NF-κB and ERK pathway.

Qiang Xu, Yan Shen, Yang Sun, 2016, International immunopharmacology.

[Studies on flavonoids from the leaves of Lindera aggregata].

Qiang Xu, Yan Shen, Jing-jing Fan, 2011, Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.

Immunosuppressive resveratrol aneuploids from Hopea chinensis.

Qiang Xu, Yan Shen, Jing Ma, 2010, Chemistry.

Inhibition of NLRP3 inflammasome activation in myeloid-derived suppressor cells by andrographolide sulfonate contributes to 5-FU sensitization in mice.

Qiang Xu, Yanhong Gu, Wenjie Guo, 2021, Toxicology and applied pharmacology.

Self-renewal and Differentiation of Muscle Satellite Cells Are Regulated by the Fas-associated Death Domain*

Qiang Xu, Wei Cheng, Rong Zhang, 2013, The Journal of Biological Chemistry.

A HER2-targeting antibody-MMAE conjugate RC48 sensitizes immunotherapy in HER2-positive colon cancer by triggering the cGAS-STING pathway

Qiang Xu, Yanhong Gu, Wenjie Guo, 2023, Cell death & disease.

[Protective effect of the extract of Terminalia catappa leaves on acute liver injury induced by D-GalN in mice].

Qiang Xu, Jing Gao, Huan Dou, 2004, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

[Hepatoprotective effects of chloroform extract from leaf of Terminalia catappa in relation to the inhibition of liver IL-6 expression].

Qiang Xu, Jing Gao, Xin-hui Tang, 2003, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

Development of a live topical microbicide for women

D. Hamer, Qiang Xu, Srinivas S. Rao, 2006, Retrovirology.