A. Johnson

发表

The first de novo designed inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase.

Timo Heikkilae, S. Thirumalairajan, M. Davies, 2006, Bioorganic & medicinal chemistry letters.

SPROUT, HIPPO and CAESA: Tools for de novo structure generation and estimation of synthetic accessibility

Valerie J. Gillet, Glenn J. Myatt, Zsolt Zsoldos, 1995 .

Molecular complexity analysis of de novo designed ligands.

A. Johnson, Krisztina Boda, 2006, Journal of medicinal chemistry.

Chapter 4.8. De-Novo Design Systems

A. Johnson, 2008 .

Validation of the SPROUT de novo design program

Imre G. Csizmadia, Aniko Simon, Zsolt Zsoldos, 2003 .

Some recent progress in the development of the LHASA computer system for organic synthesis design: Starting‐material‐oriented retrosynthetic analysis

A. Johnson, P. Judson, C. Marshall, 1992 .

A virtual high-throughput screening approach to the discovery of novel inhibitors of the bacterial leucine transporter, LeuT

C. Fishwick, A. Johnson, K. Simmons, 2013, Molecular membrane biology.

Identification of Selective Inhibitors of the Potassium Channel Kv1.1–1.2(3) by High-Throughput Virtual Screening and Automated Patch Clamp

Wiktor Jurkowski, Erik Lindahl, Bert L de Groot, 2012, ChemMedChem.

Factors influencing the specificity of inhibitor binding to the human and malaria parasite dihydroorotate dehydrogenases.

M. R. Parsons, C. Fishwick, A. Johnson, 2012, Journal of medicinal chemistry.

Cover Picture: Identification of Selective Inhibitors of the Potassium Channel Kv1.1–1.2(3) by High-Throughput Virtual Screening and Automated Patch Clamp (ChemMedChem 10/2012)

Bert L. de Groot, A. Peter Johnson, Erik Lindahl, 2012 .

Starting material oriented retrosynthetic analysis in the LHASA program. 1. General description

Philip N. Judson, Chris Marshall, A. Peter Johnson, 1992, J. Chem. Inf. Comput. Sci..

Starting Material Oriented Retrosynthetic Analysis in the LHASA Program. Part 1. General Description.

A. Johnson, P. Judson, C. Marshall, 1993 .

An in silico structure-based approach to anti-infective drug discovery

C. Fishwick, A. Johnson, Fraser Cunningham, 2013, Parasitology.

Structure-based ligand design of novel bacterial RNA polymerase inhibitors.

C. Fishwick, A. Johnson, I. Chopra, 2011, ACS medicinal chemistry letters.

Molecular mechanism of ligand recognition by membrane transport protein, Mhp1

C. Fishwick, A. Johnson, S. Iwata, 2014, The EMBO journal.

Discovery of novel non-peptide inhibitors of BACE-1 using virtual high-throughput screening.

C. Fishwick, A. Johnson, N. Hooper, 2009, Bioorganic & medicinal chemistry letters.

Computer‐aided synthesis design: 40 years on

Anthony P. F. Cook, A. Peter Johnson, James Law, 2012 .

Starting Material Oriented Retrosynthetic Analysis in the LHASA Program. Part 2. Mapping the SM and Target Structures.

A. Johnson, C. Marshall, 2010 .

Design and synthesis of potent inhibitors of the malaria parasite dihydroorotate dehydrogenase.

Timo Heikkilae, M. Davies, C. Fishwick, 2007, Journal of medicinal chemistry.

A general synthesis of 1-(1-alkenyl)benzotriazoles

A. Johnson, David P. M. Pleynet, J. Dutton, 1999 .

NOVEL METALLATION OF BENZOTRIAZOLES AND ITS UTILITY IN THE SYNTHESIS OF 4-SUBSTITUTED OXINDOLES

A. Johnson, M. Thornton-Pett, David P. M. Pleynet, 1995 .

Synthesis and reactions of N,N-bis[1-(trimethylsiloxy)alkyl]-formamides: preparation of (±)-argemonine and (±)-norargemonine

A. Johnson, R. Luke, A. N. Boa, 1996 .

A total synthesis of gelsemine: oxindole spiroannelation

A. Johnson, A. Tasker, R. Steel, 1994 .

A total synthesis of gelsemine: synthesis of a key tetracyclic intermediate

A. Johnson, A. Tasker, R. Steel, 1994 .

Synthesis of hindered spiro-oxindoles by photolysis of 1-(1-alkenyl)benzotriazoles

A. Johnson, David P. M. Pleynet, J. Dutton, 1999 .

Reactions of 1-Acylamino-1-(trimethylsiloxy)alkanes: Versatile Precursors to Acylimines.

A. Johnson, R. Luke, A. N. Boa, 1996 .

Synthesis of 1-acylamino-1-(trimethylsiloxy)alkanes by trimethylsilyl trifluoromethanesulfonate-catalysed addition of bis(trimethylsilyl)amides to aldehydes

R. W. Steele, A. Johnson, R. Luke, 1996 .

The CIP sequence rules: Analysis and proposal for a revision

Paulina Mata, Chris Marshall, A. Johnson, 1993 .

eHiTS: an innovative approach to the docking and scoring function problems.

Aniko Simon, Zsolt Zsoldos, Darryl Reid, 2006, Current protein & peptide science.

Route Designer: A Retrosynthetic Analysis Tool Utilizing Automated Retrosynthetic Rule Generation

Yang Liu, Howard Y. Ando, James Law, 2009, J. Chem. Inf. Model..

Macrocyclic inhibitors of the bacterial cell wall biosynthesis enzyme MurD.

C. Fishwick, A. Johnson, S. Phillips, 2003, Bioorganic & medicinal chemistry letters.

eHiTS: a new fast, exhaustive flexible ligand docking system.

Aniko Simon, Zsolt Zsoldos, Darryl Reid, 2007, Journal of molecular graphics & modelling.

Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness

M. Nardini, M. Bolognesi, C. Fishwick, 2018 .

A study of the effects of substituents on the selectivity of the binding of N-arylaminomethylene malonate inhibitors to DHODH.

C. Fishwick, A. Johnson, G. McConkey, 2010, Bioorganic & medicinal chemistry letters.

Novel Treatment of Conformational Flexibility Using Interval Analysis

Zsuzsanna Szabó, Miklós Vargyas, A. Peter Johnson, 2000, J. Chem. Inf. Comput. Sci..

Computational tools for structure-based design

A. Peter Johnson, Stuart Green, A. Johnson, 1997 .

Structure-based design, synthesis, and characterization of inhibitors of human and Plasmodium falciparum dihydroorotate dehydrogenases.

M. Davies, M. R. Parsons, C. Fishwick, 2009, Journal of medicinal chemistry.

Synthesis of de novo designed small-molecule inhibitors of bacterial RNA polymerase

Colin W. G. Fishwick, C. Fishwick, A. Johnson, 2008 .

Chemical literature data extraction: The CLiDE Project

A. Peter Johnson, T. Venczel, Christian A. G. Tonnelier, 1993, J. Chem. Inf. Comput. Sci..

Expert System Assisted Pharmacophore Identification

Ross McGuire, Stuart Green, A. Peter Johnson, 2000, J. Chem. Inf. Comput. Sci..

SPROUT: Recent developments in the de novo design of molecules

Valerie J. Gillet, Glenn J. Myatt, A. Peter Johnson, 1994, J. Chem. Inf. Comput. Sci..

SPROUT: A program for structure generation

Valerie J. Gillet, Philip Williams, A. Peter Johnson, 1993, J. Comput. Aided Mol. Des..

Derivatives of pyrimidine, phthalimide and anthranilic acid as inhibitors of human hydroxysteroid dehydrogenase AKR1C1.

M. Davies, C. Fishwick, A. Johnson, 2009, Chemico-biological interactions.

Discovery of biphenylacetamide-derived inhibitors of BACE1 using de novo structure-based molecular design.

Nigel M Hooper, C. Fishwick, A. Johnson, 2013, Journal of medicinal chemistry.

SPROUT: 3D Structure Generation Using Templates

Valerie J. Gillet, Glenn J. Myatt, A. Peter Johnson, 1995, J. Chem. Inf. Comput. Sci..

Implementation of the Cahn-Ingold-Prelog System for Stereochemical Perception in the LHASA Program

Chris Marshall, A. Peter Johnson, Ana M. Lobo, 1994, J. Chem. Inf. Comput. Sci..

Development and preliminary test results of an expert system for the automatic generation of tropospheric VOC degradation mechanisms

Stephen Pascoe, Michael J. Pilling, Sandra M. Saunders, 2003 .

A de novo designed inhibitor of D-Ala-D-Ala ligase from E. coli.

C. Fishwick, A. Johnson, I. Chopra, 2005, Angewandte Chemie.

CLiDE Pro: The Latest Generation of CLiDE, a Tool for Optical Chemical Structure Recognition

A. Peter Johnson, Aniko T. Valko, A. Johnson, 2009, J. Chem. Inf. Model..

Recent Advances in the CLiDE Project: Logical Layout Analysis of Chemical Documents

A. Peter Johnson, Anikó Simon, A. Johnson, 1997, J. Chem. Inf. Comput. Sci..

A Fast Algorithm for Bottom-Up Document Layout Analysis

A. Peter Johnson, Anikó Simon, Jean-Christophe Pret, 1997, IEEE Trans. Pattern Anal. Mach. Intell..

The reaction of skatole with 3-chloro-3-methylbut-1-yne: a novel ring expansion involving an allenic carbene

A. Johnson, B. Bycroft, W. Landon, 1969 .

Computer-Assisted Synthetic Analysis. Long-Range Search Procedures for Antithetic Simplification of Complex Targets by Application of the Halolactonization Transform

Johann Mulzer, E. J. Corey, Alan K. Long, 1980, J. Chem. Inf. Comput. Sci..

Automated structure design in 3D

Valerie J. Gillet, A. P. Johnson, Sandor Sike, 1990 .

An algorithm for the multiple common subgraph problem

A. Peter Johnson, Denis M. Bayada, Claude Laurenço, 1992, Journal of chemical information and computer sciences.

Detection of the Largest Patterns Common to a Set of Molecules, Using 2D Graphs and 3D Skeletons

A. Peter Johnson, Denis M. Bayada, A. Johnson, 1995 .

A novel method of aligning molecules by local surface shape similarity

David A. Cosgrove, A. Peter Johnson, Denis M. Bayada, 2000, J. Comput. Aided Mol. Des..