T. Curtis

发表

Fast Retinal Vessel Detection and Measurement Using Wavelets and Edge Location Refinement

P. Bankhead, C. Scholfield, J. Mcgeown, 2012, PloS one.

Deep Sequencing Reveals Predominant Expression of miR-21 Amongst the Small Non-Coding RNAs in Retinal Microvascular Endothelial Cells

T. Curtis, Alan W. Stitt, Jasenka Guduric-Fuchs, 2012, Journal of cellular biochemistry.

T. Curtis, Alan W. Stitt, 2011, Journal of ocular biology, diseases, and informatics.

Detecting Ca2+ sparks on stationary and varying baselines.

P. Bankhead, C. Scholfield, J. Mcgeown, 2011, American journal of physiology. Cell physiology.

Arteriolar Involvement in the Microvascular Lesions of Diabetic Retinopathy: Implications for Pathogenesis

T. Curtis, Alan W. Stitt, D. Archer, 2007, Microcirculation.

Single-cell transcriptomic profiling provides insights into retinal endothelial barrier properties

T. Curtis, P. Barabas, D. Simpson, 2020, Molecular vision.

Rod photoreceptor loss in Rho-/- mice reduces retinal hypoxia and hypoxia-regulated gene expression.

T. Curtis, Alan W. Stitt, T. Gardiner, 2006, Investigative ophthalmology & visual science.

CAMKII as a therapeutic target for growth factor–induced retinal and choroidal neovascularization

J. Mcgeown, T. Curtis, Alan W. Stitt, 2019, JCI insight.

Acridine orange leukocyte fluorography in mice.

P. Bankhead, J. Mcgeown, T. Curtis, 2014, Experimental eye research.

Methods in eye research Acridine orange leukocyte fl uorography in mice q

P. Bankhead, J. Mcgeown, T. Curtis, 2014 .

The modes of action of toxicants on the cardiac physiology of the blue mussel, Mytilus edulis, and the common shore crab, Carcinus maenas

T. Curtis, 1998 .

VEGF-B Is an Autocrine Gliotrophic Factor for Müller Cells under Pathologic Conditions

T. Curtis, P. Barabas, J. Lechner, 2020, Investigative ophthalmology & visual science.

Intravitreal AAV2.COMP-Ang1 Attenuates Deep Capillary Plexus Expansion in the Aged Diabetic Mouse Retina

T. Curtis, Alan W. Stitt, Malkit Singh, 2019, Investigative ophthalmology & visual science.

Retina Intravitreal AAV 2 . COMP-Ang 1 Attenuates Deep Capillary Plexus Expansion in the Aged Diabetic Mouse Retina

T. Curtis, Alan W. Stitt, Malkit Singh, 2019 .

Effects of the organophosphorous pesticide, dimethoate, on cardiac and acetylcholinesterase (AChE) activity in the shore crab Carcinus maenas

T. Curtis, M. Depledge, J. Braven, 1997 .

Increased expression of bronchial epithelial transient receptor potential vanilloid 1 channels in patients with severe asthma.

T. Curtis, P. Bradding, M. Ennis, 2014, The Journal of allergy and clinical immunology.

Hyperglycaemia-induced pro-inflammatory responses by retinal Müller glia are regulated by the receptor for advanced glycation end-products (RAGE)

G. A. Limb, T. Curtis, Alan W. Stitt, 2010, Diabetologia.

Kv1.5 is a major component underlying the A-type potassium current in retinal arteriolar smooth muscle

C. Scholfield, T. Curtis, Alan W. Stitt, 2006, American journal of physiology. Heart and circulatory physiology.

Retinal endothelial cell apoptosis stimulates recruitment of endothelial progenitor cells.

T. Curtis, J. Glenn, Alan W. Stitt, 2009, Investigative ophthalmology & visual science.

Diabetes-induced activation of protein kinase C inhibits store-operated Ca2+ uptake in rat retinal microvascular smooth muscle

C. Scholfield, T. Curtis, E. Trimble, 2003, Diabetologia.

Müller glial dysfunction during diabetic retinopathy in rats is linked to accumulation of advanced glycation end-products and advanced lipoxidation end-products

T. Curtis, Alan W. Stitt, K. Uchida, 2011, Diabetologia.

cAMP/PKA-dependent increases in Ca Sparks, oscillations and SR Ca stores in retinal arteriolar myocytes after exposure to vasopressin.

P. Bankhead, C. Scholfield, J. Mcgeown, 2010, Investigative ophthalmology & visual science.

Ca-Sparks, Oscillations and SR Ca-stores are Increased in Retinal Arteriolar Myocytes via a cAMP/PKA Dependent Pathway Following Exposure to Vasopressin

P. Bankhead, J. Mcgeown, T. Curtis, 2009 .

Selective Downregulation of the BKβ1 Subunit in Diabetic Arteriolar Myocytes

C. Scholfield, J. Mcgeown, T. Curtis, 2007, Channels.

Role of ion channels and subcellular Ca2+ signaling in arachidonic acid-induced dilation of pressurized retinal arterioles.

C. Scholfield, J. Mcgeown, T. Curtis, 2014, Investigative ophthalmology & visual science.

Advanced glycation of fibronectin impairs vascular repair by endothelial progenitor cells: implications for vasodegeneration in diabetic retinopathy.

T. Curtis, J. Glenn, Alan W. Stitt, 2008, Investigative ophthalmology & visual science.

CaV3.1 T-Type Ca2+ Channels Contribute to Myogenic Signaling in Rat Retinal Arterioles.

J. Mcgeown, T. Curtis, M. Mcgahon, 2015, Investigative ophthalmology & visual science.

Isolation of Retinal Arterioles for Ex Vivo Cell Physiology Studies

C. Scholfield, T. Curtis, P. Barabas, 2018, Journal of visualized experiments : JoVE.

TRPA1 activation in a human sensory neuronal model: relevance to cough hypersensitivity?

J. Mcgeown, T. Curtis, I. About, 2017, European Respiratory Journal.

Substrates modified by advanced glycation end-products cause dysfunction and death in retinal pericytes by reducing survival signals mediated by platelet-derived growth factor

T. Curtis, Alan W. Stitt, T. Cotter, 2004, Diabetologia.

Pharmacological Profiling of Store‐Operated Ca2+ Entry in Retinal Arteriolar Smooth Muscle

C. Scholfield, T. Curtis, D. Simpson, 2012, Microcirculation.

Biodentine Reduces Tumor Necrosis Factor Alpha-induced TRPA1 Expression in Odontoblastlike Cells.

Maelíosa T. C. McCrudden, T. Curtis, I. About, 2016, Journal of endodontics.

TRP channels in vascular disorders.

T. Curtis, A. Zholos, 2013, Current topics in medicinal chemistry.

Loss of TRPV2-mediated blood flow autoregulation recapitulates diabetic retinopathy in rats

T. Curtis, Alan W. Stitt, P. Barabas, 2022, JCI insight.

Molecular mechanisms mediating the beneficial metabolic effects of [Arg4]tigerinin-1R in mice with diet-induced obesity and insulin resistance

T. Curtis, D. Srinivasan, J. Conlon, 2016, Biological chemistry.

Heterogeneity in cytosolic calcium regulation among different microvascular smooth muscle cells of the rat retina.

C. Scholfield, T. Curtis, 2000, Microvascular research.

Royal Academy of Medicine in Ireland Section of Biomedical Sciences

C. Scholfield, T. Curtis, S. McDonough, 1999 .

Esculentin-2CHa(1-30) and its analogues: stability and mechanisms of insulinotropic action.

T. Curtis, J. Conlon, P. Flatt, 2017, The Journal of endocrinology.

Esculentin-2 CHa ( 1-30 ) and its analogues – stability and mechanisms of insulinotropic 1 action 2 3

T. Curtis, P. Flatt, R. Moffett, 2017 .

PAR-2 Regulates Dental Pulp Inflammation Associated with Caries

T. Curtis, I. About, C. Irwin, 2010, Journal of dental research.

Müller glial dysfunction during diabetic retinopathy in rats is reduced by the acrolein-scavenging drug, 2-hydrazino-4,6-dimethylpyrimidine

J. Mcgeown, T. Curtis, P. Barabas, 2018, Diabetologia.

Zinc Protects Oxidative Stress-Induced RPE Death by Reducing Mitochondrial Damage and Preventing Lysosome Rupture

T. Curtis, Mei Chen, Heping Xu, 2017, Oxidative medicine and cellular longevity.

Advanced glycation endproduct modified basement membrane attenuates endothelin-1 induced [Ca2+]i signalling and contraction in retinal microvascular pericytes.

C. Scholfield, J. Mcgeown, T. Curtis, 2004, Molecular vision.

Actions of PGLa-AM1 and its [A14K] and [A20K] analogues and their therapeutic potential as anti-diabetic agents.

T. Curtis, J. Conlon, P. Flatt, 2017, Biochimie.

Diabetes Downregulates Large-Conductance Ca2+-Activated Potassium &bgr;1 Channel Subunit in Retinal Arteriolar Smooth Muscle

C. Scholfield, T. Curtis, D. Simpson, 2007, Circulation research.

TRPV2 Channels Contribute to Stretch-Activated Cation Currents and Myogenic Constriction in Retinal Arterioles.

J. Mcgeown, T. Curtis, D. Simpson, 2016, Investigative ophthalmology & visual science.

TNF-α-induced p38MAPK activation regulates TRPA1 and TRPV4 activity in odontoblast-like cells.

Maelíosa T. C. McCrudden, T. Curtis, I. About, 2015, The American journal of pathology.

Human odontoblasts express functional thermo-sensitive TRP channels: Implications for dentin sensitivity

T. Curtis, I. About, C. Irwin, 2011, PAIN®.

VEGF-induced retinal angiogenic signaling is critically dependent on Ca²⁺ signaling by Ca²⁺/calmodulin-dependent protein kinase II.

J. Mcgeown, T. Curtis, E. Banumathi, 2011, Investigative ophthalmology & visual science.

Human dental pulp fibroblasts express the "cold-sensing" transient receptor potential channels TRPA1 and TRPM8.

T. Curtis, I. About, C. Irwin, 2011, Journal of endodontics.

Hyperglycemia and Diabetes Downregulate the Functional Expression of TRPV4 Channels in Retinal Microvascular Endothelium

J. Mcgeown, T. Curtis, C. Kelly, 2015, PloS one.

Endogenous Mas‐related G‐protein‐coupled receptor X1 activates and sensitizes TRPA1 in a human model of peripheral nerves

T. Curtis, I. About, F. Lundy, 2021, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The progress in understanding and treatment of diabetic retinopathy

Noemi Lois, T. Curtis, Alan W. Stitt, 2016, Progress in Retinal and Eye Research.

Evidence supporting a role for Nε-(3-formyl-3,4-dehydropiperidino)lysine accumulation in Müller glia dysfunction and death in diabetic retinopathy

G. A. Limb, T. Curtis, Alan W. Stitt, 2010, Molecular vision.

GABAergic control of arteriolar diameter in the rat retina.

J. Mcgeown, T. Curtis, B. Frølund, 2013, Investigative ophthalmology & visual science.

The role of lipids and protein kinase Cs in the pathogenesis of diabetic retinopathy

C. Scholfield, T. Curtis, C. Scholfield, 2004, Diabetes/metabolism research and reviews.

Advances in our understanding of diabetic retinopathy.

Noemi Lois, T. Curtis, Alan W. Stitt, 2013, Clinical science.

PKCζ-dependent upregulation of p27kip1 contributes to oxidative stress induced retinal pigment epithelial cell multinucleation

T. Curtis, Mei Chen, Heping Xu, 2017, Aging.

COMP-Ang1: Therapeutic potential of an engineered Angiopoietin-1 variant.

T. Curtis, P. Barabas, R. Wallace, 2021, Vascular pharmacology.

Advanced glycation and retinal pathology during diabetes.

T. Curtis, Alan W. Stitt, Alan W Stitt, 2005, Pharmacological reports : PR.

arteriolar smooth muscle cells

C. Scholfield, T. Curtis, Jennine Dawicki, 2008 .

A-type potassium current in retinal arteriolar smooth muscle cells.

C. Scholfield, J. Mcgeown, T. Curtis, 2005, Investigative ophthalmology & visual science.

Identification and spatiotemporal characterization of spontaneous Ca2+ sparks and global Ca2+ oscillations in retinal arteriolar smooth muscle cells.

C. Scholfield, J. Mcgeown, T. Curtis, 2004, Investigative ophthalmology & visual science.

Evidence for two endothelin EtA receptor subtypes in rabbit arteriolar smooth muscle

C. Scholfield, T. Curtis, 2001, British journal of pharmacology.

The Role of Lipoxidation in the Pathogenesis of Diabetic Retinopathy

T. Curtis, Alan W. Stitt, P. Barabas, 2021, Frontiers in Endocrinology.

Ocular Blood Flow in Diabetes: Contribution to the Microvascular Lesions of Diabetic Retinopathy

T. Curtis, T. Gardiner, 2012 .

Therapeutic potential of targeting lipid aldehydes and lipoxidation end-products in the treatment of ocular disease.

J. Mcgeown, T. Curtis, Alan W. Stitt, 2013, Future medicinal chemistry.

Nifedipine blocks Ca2+ store refilling through a pathway not involving L‐type Ca2+ channels in rabbit arteriolar smooth muscle

T. Curtis, C. Scholfield, 2001, The Journal of physiology.

Ion channels and myogenic activity in retinal arterioles.

J. Mcgeown, T. Curtis, P. Barabas, 2020, Current topics in membranes.

A trans-kingdom T6SS effector induces the fragmentation of the mitochondrial network and activates innate immune receptor NLRX1 to promote infection

T. Curtis, P. Barabas, V. J. Cid, 2023, Nature Communications.

Diabetes Impairs the Aldehyde Detoxifying Capacity of the Retina.

J. Mcgeown, T. Curtis, Mei Chen, 2016, Investigative ophthalmology & visual science.

Endothelin 1 stimulates Ca2+-sparks and oscillations in retinal arteriolar myocytes via IP3R and RyR-dependent Ca2+ release.

P. Bankhead, C. Scholfield, J. Mcgeown, 2011, Investigative ophthalmology & visual science.

Microvascular lesions of diabetic retinopathy: clues towards understanding pathogenesis?

T. Curtis, Alan W. Stitt, T. Gardiner, 2009, Eye.

Ca2+-activated Cl- current in retinal arteriolar smooth muscle.

C. Scholfield, J. Mcgeown, T. Curtis, 2009, Investigative ophthalmology & visual science.

Voltage-activated currents in cardiac myocytes of the blue mussel, Mytilus edulis

T. Curtis, R. Williamson, M. Depledge, 1999 .

Simultaneous, long-term monitoring of valve and cardiac activity in the blue mussel Mytilus edulis exposed to copper

Tim M. Curtis, Michael H. Depledge, T. Curtis, 2000 .

New developments in diabetic retinopathy

C. Scholfield, J. Mcgeown, T. Curtis, 2007 .

COMP-Ang1 Stabilizes Hyperglycemic Disruption of Blood-Retinal Barrier Phenotype in Human Retinal Microvascular Endothelial Cells

T. Curtis, P. Barabas, N. Barron, 2019, Investigative ophthalmology & visual science.

Uncoupled turnover disrupts mitochondrial quality control in diabetic retinopathy

T. Curtis, T. Lyons, D. Brazil, 2019, JCI insight.

Involvement of TRPV1 and TRPV4 Channels in Retinal Angiogenesis.

T. Curtis, Alan W. Stitt, P. Barabas, 2019, Investigative ophthalmology & visual science.

Rat Hippocampal Neurons by Intracellular Arachidonic Acid in A I K-CurrentDownmodulation of the Transient

W. Müller, C. Scholfield, T. Curtis, 2015 .

Independent Variable Retinal Ganglion Cells: Using Temperature as an Mechanisms and Distribution of Ion Channels in

M. Ibbotson, B. O'Brien, P. Bankhead, 2015 .

Ca2+-sparks constitute elementary building blocks for global Ca2+-signals in myocytes of retinal arterioles

T. Curtis, N. Scholfield, G. McGeown, 2007, Cell calcium.

Evaluation of Nε-(3-formyl-3,4-dehydropiperidino)lysine as a novel biomarker for the severity of diabetic retinopathy

T. Curtis, Alan W. Stitt, T. Gardiner, 2008, Diabetologia.

Transient Ca2+-activated Cl-currents with endothelin in isolated arteriolar smooth muscle cells of the choroid.

C. Scholfield, T. Curtis, 2000, Investigative ophthalmology & visual science.

The role of K+ and Cl- channels in the regulation of retinal arteriolar tone and blood flow.

P. Bankhead, C. Scholfield, T. Curtis, 2014, Investigative ophthalmology & visual science.

Modification of smooth muscle Ca2+-sparks by tetracaine: evidence for sequential RyR activation.

C. Scholfield, T. Curtis, M. Mcgahon, 2008, Cell calcium.

Automated Detection and Measurement of Isolated Retinal Arterioles by a Combination of Edge Enhancement and Cost Analysis

P. Bankhead, J. Mcgeown, T. Curtis, 2014, PloS one.

Feedback via Ca²⁺-activated ion channels modulates endothelin 1 signaling in retinal arteriolar smooth muscle.

P. Bankhead, C. Scholfield, J. Mcgeown, 2012, Investigative ophthalmology & visual science.

Aldehyde Dehydrogenase and Aldo-Keto Reductase Enzymes: Basic Concepts and Emerging Roles in Diabetic Retinopathy

T. Curtis, Josy Augustine, A. Stitt, 2023, Antioxidants.