I. Taylor

发表

Characterization of the DNA-binding domains from the yeast cell-cycle transcription factors Mbp1 and Swi4.

I. Taylor, P. McIntosh, P. Pala, 2000, Biochemistry.

KH-RNA interactions: back in the groove.

I. Taylor, G. Nicastro, A. Ramos, 2015, Current opinion in structural biology.

The design of artificial retroviral restriction factors.

I. Taylor, M. Yap, G. Mortuza, 2007, Virology.

The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms.

D. Durocher, M. Yaffe, I. Taylor, 2000, Molecular cell.

Eleventh International Foamy Virus Conference—Meeting Report

I. Taylor, M. Soares, M. Löchelt, 2016, Viruses.

A Unique Spumavirus Gag N-terminal Domain with Functional Properties of Orthoretroviral Matrix and Capsid

I. Taylor, D. Lindemann, Nicole Stanke, 2013, PLoS pathogens.

Structure of a Mycobacterium tuberculosis NusA–RNA complex

I. Taylor, Stephen R. Martin, S. Pennell, 2005, The EMBO journal.

Structure and catalytic mechanism of the human histone methyltransferase SET7/9

Geoff Kelly, Steven J. Gamblin, Jon R. Wilson, 2003, Nature.

Preferential binding of fd gene 5 protein to tetraplex nucleic acid structures.

I. Taylor, G. Kneale, A. Oliver, 2000, Journal of molecular biology.

Substrate recognition and selectivity in the type IC DNA modification methylase M.EcoR124I.

I. Taylor, G. Kneale, D. Watts, 1993, Nucleic acids research.

A competition assay for DNA binding using the fluorescent probe ANS.

I. Taylor, G. Kneale, 1994, Methods in molecular biology.

DNA‐binding induces a major structural transition in a type I methyltransferase.

I. Taylor, G. Kneale, K. Davis, 1994, The EMBO journal.

Probing the domain structure of the type IC DNA methyltransferase M.EcoR124I by limited proteolysis.

I. Taylor, K. Firman, G. Kneale, 1995, Journal of molecular biology.

Surface labelling of the type I methyltransferase M.EcoR124I reveals lysine residues critical for DNA binding.

I. Taylor, G. Kneale, M. Webb, 1996, Journal of molecular biology.

A comparative analysis of the foamy and ortho virus capsid structures reveals an ancient domain duplication

W. Taylor, I. Taylor, J. Stoye, 2017, BMC Structural Biology.

Structure of D. melanogaster ARC1 reveals a repurposed molecule with characteristics of retroviral Gag

I. Taylor, J. Stoye, M. Cottee, 2019, bioRxiv.

Structural basis for Fullerene geometry in a human endogenous retrovirus capsid

I. Taylor, G. Nicastro, A. Ramos, 2019, Nature Communications.

Structure of the Rna15 RRM–RNA complex reveals the molecular basis of GU specificity in transcriptional 3′-end processing factors

I. Taylor, A. Ramos, D. Goldstone, 2010, Nucleic acids research.

RNA polymerase II CTD phosphopeptides compete with RNA for the interaction with Pcf11.

I. Taylor, A. Ramos, C. Noble, 2006, RNA.

Btbd6-dependent Plzf recruitment to Cul3 E3 ligase complexes through BTB domain heterodimerization

I. Taylor, S. Howell, S. Smerdon, 2019, bioRxiv.

Single cell multiomic analysis of T cell exhaustion in vitro

I. Taylor, P. Chattopadhyay, Woodrow E. Lomas, 2019, bioRxiv.

Single cell multiomic analysis of T cell exhaustion in vitro

Margaret A. Nakamoto, I. Taylor, P. Chattopadhyay, 2019, bioRxiv.

Scaffold-independent analysis of RNA-protein interactions: the Nova-1 KH3-RNA complex.

I. Taylor, A. Ramos, M. García-Mayoral, 2007, Journal of the American Chemical Society.

Multivalent interactions essential for lentiviral integrase function

A. Engelman, I. Taylor, N. Cook, 2022, Nature communications.

A supramolecular assembly mediates lentiviral DNA integration

A. Engelman, Erik Serrao, I. Taylor, 2017, Science.

Structural basis of lentiviral subversion of a cellular protein degradation pathway

I. Taylor, D. Schwefel, P. Walker, 2013, Nature.

An RRM–ZnF RNA recognition module targets RBM10 to exonic sequences to promote exon exclusion

T. Hughes, Q. Morris, D. Ray, 2017, Nucleic acids research.

Positive selection in dNTPase SAMHD1 throughout mammalian evolution

I. Taylor, R. Goldstein, A. Fassati, 2019, Proceedings of the National Academy of Sciences.

CP-MAS and solution NMR studies of allosteric communication in CA-assemblies of HIV-1.

I. Taylor, G. Nicastro, T. Frenkiel, 2022, Journal of molecular biology.

Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis

I. Taylor, A. Purkiss, S. Caswell, 2020, Nature Communications.

Expression, purification, and crystallization of the DNA‐binding domain from the Saccharomyces cerevisae cell‐cycle transcription factor MBP‐1

I. Taylor, S. Smerdon, 1997, Proteins.

A nuclear export signal in KHNYN required for its antiviral activity evolved as ZAP emerged in tetrapods

I. Taylor, S. Neil, H. Winstone, 2022, bioRxiv.

Factor Substitution inaHumanHSP70GenePromoter: TATA- Dependent andTATA-Independent Interactions

I. Taylor, A. Kingston, 1990 .

Eleventh International Foamy Virus Conference 2016 Meeting Report

I. Taylor, M. Soares, M. Löchelt, 2018 .

Sedimentation equilibrium studies.

I. Taylor, K. Rittinger, J. Eccleston, 2015, Methods in molecular biology.

The eukaryotic elongation factor eEF1A1 interacts with SAMHD1.

I. Taylor, Y. Crow, D. Schwefel, 2015, The Biochemical journal.

The Eukaryotic-Specific ISD11 Is a Complex-Orphan Protein with Ability to Bind the Prokaryotic IscS

M. Huynen, I. Taylor, A. Pastore, 2016, PloS one.

Diffuse scattering resulting from macromolecular frustration.

I. Taylor, T. Welberry, D. Goldstone, 2011, Acta crystallographica. Section B, Structural science.

SAMHD1 enhances nucleoside-analogue efficacy against HIV-1 in myeloid cells

I. Taylor, H. Groom, M. Yap, 2017, Scientific Reports.

Interaction of the type I methyltransferase M.EcoR124I with modified DNA substrates: sequence discrimination and base flipping.

I. Taylor, G. Kneale, D. Mernagh, 1998, The Biochemical journal.

HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase

Geoff Kelly, Michelle Webb, Jonathan P. Stoye, 2011, Nature.

Targeting the nucleotide salvage factor DNPH1 sensitizes BRCA-deficient cells to PARP inhibitors

S. West, I. Taylor, T. Carell, 2021, Science.

The influence of DNA binding on the backbone dynamics of the yeast cell-cycle protein Mbp1*

I. Taylor, P. McIntosh, A. Lane, 2000, Journal of biomolecular NMR.

Probing the Catalytic Mechanism and Inhibition of SAMHD1 Using the Differential Properties of Rp- and Sp-dNTPαS Diastereomers

I. Taylor, A. Purkiss, S. Caswell, 2021, Biochemistry.

The missing link: allostery and catalysis in the anti-viral protein SAMHD1

I. Taylor, E. R. Morris, 2019, Biochemical Society transactions.

Phospho-dependent Regulation of SAMHD1 Oligomerisation Couples Catalysis and Restriction

I. Taylor, S. Howell, H. Groom, 2015, PLoS pathogens.

Molecular Determinants for Recognition of Divergent SAMHD1 Proteins by the Lentiviral Accessory Protein Vpx

I. Taylor, D. Schwefel, P. Walker, 2015, Cell host & microbe.

A Continuous Enzyme-Coupled Assay for Triphosphohydrolase Activity of HIV-1 Restriction Factor SAMHD1

I. Taylor, M. Webb, S. Kunzelmann, 2014, Antimicrobial Agents and Chemotherapy.

NEMO oligomerization and its ubiquitin-binding properties

Katrin Rittinger, I. Taylor, K. Rittinger, 2009, The Biochemical journal.

Structural and functional analysis of prehistoric lentiviruses uncovers an ancient molecular interface.

W. Taylor, I. Taylor, A. Katzourakis, 2010, Cell host & microbe.

Functional role of TRIM E3 ligase oligomerization and regulation of catalytic activity

I. Taylor, K. Rittinger, E. Christodoulou, 2016, The EMBO journal.

Structural studies of postentry restriction factors reveal antiparallel dimers that enable avid binding to the HIV-1 capsid lattice

I. Taylor, P. Rosenthal, P. Walker, 2014, Proceedings of the National Academy of Sciences.

The Drug-Induced Interface That Drives HIV-1 Integrase Hypermultimerization and Loss of Function

A. Engelman, I. Taylor, N. Cook, 2023, mBio.

Chk2 Oligomerization Studied by Phosphopeptide Ligation

I. Taylor, S. Howell, S. Smerdon, 2008, Journal of Biological Chemistry.

Structure of a Spumaretrovirus Gag Central Domain Reveals an Ancient Retroviral Capsid

W. Taylor, I. Taylor, G. Nicastro, 2016, PLoS pathogens.

Novel Escape Mutants Suggest an Extensive TRIM5α Binding Site Spanning the Entire Outer Surface of the Murine Leukemia Virus Capsid Protein

I. Taylor, M. Yap, J. Stoye, 2011, PLoS pathogens.

Characterization of an Amino-Terminal Dimerization Domain from Retroviral Restriction Factor Fv1

I. Taylor, S. Howell, M. Yap, 2006, Journal of Virology.

Structural basis of dimerization and dual W-box DNA recognition by rice WRKY domain

I. Taylor, You-Liang Peng, Yanxiang Zhao, 2019, Nucleic acids research.

The Gammaretroviral p12 protein has multiple domains that function during the early stages of replication

I. Taylor, D. Allen, D. Wight, 2012, Retrovirology.

Assembly of a 20-nm protein cage by Escherichia coli 2-hydroxypentadienoic acid hydratase.

I. Taylor, A. Coker, S. Wood, 2010, Journal of molecular biology.

X–ray structural analysis of the yeast cell cycle regulator Swi6 reveals variations of the ankyrin fold and has implications for Swi6 function

I. Taylor, S. Smerdon, S. Sedgwick, 1999, Nature Structural Biology.

Structural and functional architecture of the yeast cell-cycle transcription factor swi6.

I. Taylor, M. Treiber, S. Howell, 1998, Journal of molecular biology.

The speed of GTP hydrolysis determines GTP cap size and controls microtubule stability

I. Taylor, T. Surrey, Johanna Roostalu, 2019, bioRxiv.

Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses

I. Taylor, T. Mielke, C. Spahn, 2021, bioRxiv.

New insights into the GINS complex explain the controversy between existing structural models

I. Taylor, A. Patwardhan, M. Carroni, 2017, Scientific reports.

Structural properties of the human respiratory syncytial virus P protein: Evidence for an elongated homotetrameric molecule that is the smallest orthologue within the family of paramyxovirus polymerase cofactors

I. Taylor, P. Gómez-Puertas, E. López-Viñas, 2008, Proteins.

Key features of the interaction between Pcf11 CID and RNA polymerase II CTD

Geoff Kelly, Andres Ramos, I. Taylor, 2005, Nature Structural &Molecular Biology.

Ordered assembly of murine leukemia virus capsid protein on lipid nanotubes directs specific binding by the restriction factor, Fv1

I. Taylor, R. Matadeen, P. Rosenthal, 2011, Proceedings of the National Academy of Sciences.

A positive‐charged patch and stabilized hydrophobic core are essential for avirulence function of AvrPib in the rice blast fungus

I. Taylor, You-Liang Peng, Yanxiang Zhao, 2018, The Plant journal : for cell and molecular biology.

Structure of a nucleotide-bound Clp1-Pcf11 polyadenylation factor

I. Taylor, B. Beuth, C. Noble, 2006, Nucleic acids research.

Structural characterisation of the Chaetomium thermophilum Chl1 helicase

I. Taylor, M. Singleton, P. Cherepanov, 2021, PloS one.

Large Multimeric Assemblies of Nucleosome Assembly Protein and Histones Revealed by Small-angle X-ray Scattering and Electron Microscopy*

F. Karimi Nejadasl, I. Taylor, R. Ravelli, 2012, The Journal of Biological Chemistry.

Rna14-Rna15 assembly mediates the RNA-binding capability of Saccharomyces cerevisiae cleavage factor IA.

I. Taylor, P. Walker, L. Calder, 2004, Nucleic acids research.

HIV-1 requires capsid remodelling at the nuclear pore for nuclear entry and integration

I. Taylor, O. Cosnefroy, Anabel Guedán, 2021, bioRxiv.

HIV-1 capsid is involved in post-nuclear entry steps

I. Taylor, G. Nicastro, J. Luban, 2016, Retrovirology.

DNA damage induced by topoisomerase inhibitors activates SAMHD1 and blocks HIV‐1 infection of macrophages

I. Taylor, Ravindra K. Gupta, P. Mlcochova, 2017, The EMBO journal.

Structure of a Ty1 restriction factor reveals the molecular basis of transposition copy number control

D. Garfinkel, I. Taylor, J. Stoye, 2021, Nature Communications.

High-resolution structure of a retroviral capsid hexameric amino-terminal domain

I. Taylor, S. Smerdon, L. Haire, 2004, Nature.

Chemical modification of lysine by reductive methylation. A probe for residues involved in DNA binding.

I. Taylor, M. Webb, 2001, Methods in molecular biology.

IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties

I. Taylor, A. Ramos, A. Purkiss, 2019, Nucleic acids research.

IMP 1 KH 1 and KH 2 domains create a structural platform with unique RNA recognition and remodelling properties

I. Taylor, A. Ramos, Andrew, 2019 .

The crystal structure of the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia at 1.7 A resolution.

I. Taylor, S. Gamblin, C. Verma, 1998, Journal of molecular biology.

FAN1 Activity on Asymmetric Repair Intermediates Is Mediated by an Atypical Monomeric Virus-type Replication-Repair Nuclease Domain

D. Lilley, I. Taylor, S. Smerdon, 2014, Cell reports.

Substitution of tryptophan 89 with tyrosine switches the DNA binding mode of PC4

I. Taylor, You-Liang Peng, Yanxiang Zhao, 2015, Scientific Reports.

A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets

I. Taylor, A. Ramos, Alfredo Castello, 2018, Nature Communications.

Structure of B-MLV capsid amino-terminal domain reveals key features of viral tropism, gag assembly and core formation.

I. Taylor, Mark P. Dodding, L. Haire, 2008, Journal of molecular biology.

Structural basis of DNA recognition by PCG2 reveals a novel DNA binding mode for winged helix-turn-helix domains

I. Taylor, You-Liang Peng, Yanxiang Zhao, 2014, Nucleic acids research.

Structure of Drosophila melanogaster ARC1 reveals a repurposed molecule with characteristics of retroviral Gag

I. Taylor, J. Stoye, M. Cottee, 2020, Science Advances.

Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis

I. Taylor, A. Purkiss, S. Caswell, 2020, Nature Communications.

Attenuation of reverse transcriptase facilitates SAMHD1 restriction of HIV-1 in cycling cells

I. Taylor, S. Caswell, S. Pennell, 2023, Retrovirology.

Multivalent interactions essential for lentiviral integrase function

A. Engelman, I. Taylor, N. Cook, 2022, Nature Communications.

The X-ray structure of the DNA-binding domain from the Saccharomyces cerevisiae cell-cycle transcription factor Mbp1 at 2.1 A resolution.

I. Taylor, M. Treiber, S. Smerdon, 1997, Journal of molecular biology.

NMR structure of the DNA-binding domain of the cell cycle protein Mbp1 from Saccharomyces cerevisiae.

Geoff Kelly, Andrew N Lane, I. Taylor, 2003, Biochemistry.

Virus restriction: Repurposing an essential cellular function to defend against viruses

I. Taylor, J. Stoye, 2022, Current Biology.

Direct m6A recognition by IMP1 underlays an alternative model of target selection for non-canonical methyl-readers

I. Taylor, G. Nicastro, R. Patani, 2023, Nucleic acids research.

Erratum: High-resolution structure of a retroviral capsid hexameric amino-terminal domain

I. Taylor, S. Smerdon, L. Haire, 2004, Nature.

Structure of the capsid amino-terminal domain from the betaretrovirus, Jaagsiekte sheep retrovirus.

W. Taylor, I. Taylor, M. Palmarini, 2009, Journal of molecular biology.

A study of the ultrastructure of Fragile-X-related proteins

I. Taylor, A. Pastore, D. Svergun, 2009, The Biochemical journal.

Human endogenous retrovirus (HML2) mature capsid assembly, T=3 icosahedron

I. Taylor, G. Nicastro, A. Ramos, 2019 .

A Nuclear Export Signal in KHNYN Required for Its Antiviral Activity Evolved as ZAP Emerged in Tetrapods

I. Taylor, S. Neil, H. Winstone, 2023, Journal of virology.

Structure based function-annotation of hypothetical protein MGG_01005 from Magnaporthe oryzae reveals it is the dynein light chain orthologue of dynlt1/3

I. Taylor, You-Liang Peng, Jun Yang, 2018, Scientific Reports.

Structure of B-tropic MLV capsid N-terminal domain

I. Taylor, L. Haire, J. Stoye, 2008 .