Siân Jones

发表

Distant Metastasis Occurs Late during the Genetic Evolution of Pancreatic Cancer

M. Nowak, K. Kinzler, B. Vogelstein, 2010, Nature.

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

D. Busam, R. Strausberg, G. Parmigiani, 2008, Science.

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

G. Parmigiani, K. Kinzler, B. Vogelstein, 2008, Science.

The Genomic Landscapes of Human Breast and Colorectal Cancers

A. Sparks, G. Parmigiani, J. Ptak, 2007, Science.

Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers

G. Parmigiani, L. Wood, K. Kinzler, 2008, Proceedings of the National Academy of Sciences.

The Consensus Coding Sequences of Human Breast and Colorectal Cancers

G. Parmigiani, J. Ptak, L. Wood, 2006, Science.

Recurrent KRAS codon 146 mutations in human colorectal cancer

Sarah Edkins, Simon Forbes, Helen Davies, 2006, Cancer biology & therapy.

A machine learning approach for somatic mutation discovery

Rachel Karchin, Valsamo Anagnostou, David Riley, 2018, Science Translational Medicine.

Autosomal recessive colorectal adenomatous polyposis due to inherited mutations of MYH

Siân Jones, D. Evans, J. Maynard, 2003, The Lancet.

A multidimensional analysis of genes mutated in breast and colorectal cancers.

G. Parmigiani, L. Wood, K. Kinzler, 2007, Genome research.

The Genetic Landscape of the Childhood Cancer Medulloblastoma

Zev A. Binder, G. Parmigiani, M. Berger, 2011, Science.

Somatic mutations in the notch, NF‐KB, PIK3CA, and hedgehog pathways in human breast cancers

L. Wood, Siân Jones, H. Carter, 2012, Genes, chromosomes & cancer.

The Genomic Landscape of Response to EGFR Blockade in Colorectal Cancer

R. Scharpf, V. Velculescu, Siân Jones, 2015, Nature.

CoGAPS matrix factorization algorithm identifies transcriptional changes in AP-2alpha target genes in feedback from therapeutic inhibition of the EGFR network

Alexander V. Favorov, Daria A. Gaykalova, Genevieve L. Stein-O’Brien, 2016, Oncotarget.

Targeted sequencing reveals clonal genetic changes in the progression of early lung neoplasms and paired circulating DNA

Siân Jones, L. Marchionni, E. Fertig, 2015, Nature Communications.

Personalized genomic analyses for cancer mutation discovery and interpretation

Theresa Zhang, Victor E. Velculescu, Valsamo Anagnostou, 2015, Science Translational Medicine.

Direct detection of early-stage cancers using circulating tumor DNA

Sam Angiuoli, Jacob Fiksel, Valsamo Anagnostou, 2017, Science Translational Medicine.

Integrated Next-Generation Sequencing and Avatar Mouse Models for Personalized Cancer Treatment

Alfonso Valencia, Manuel Hidalgo, Samuel V. Angiuoli, 2014, Clinical Cancer Research.

Exomic Sequencing Identifies PALB2 as a Pancreatic Cancer Susceptibility Gene

Alison P. Klein, James R. Eshleman, Giovanni Parmigiani, 2009, Science.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two

Manish R. Patel, Charles J. Vaske, Joe Y. Chang, 2016, Journal for Immunotherapy of Cancer.

Inherited rare, deleterious variants in ATM increase lung adenocarcinoma risk

M. Zauderer, C. Rudin, V. Velculescu, 2020, medRxiv.

Characterizing mutations in samples with low‐level mosaicism by collection and analysis of DHPLC fractionated heteroduplexes

Siân Jones, J. Maynard, J. Cheadle, 2003, Human mutation.

Automated next-generation profiling of genomic alterations in human cancers

David R. Riley, Derrick E. Wood, Samuel V. Angiuoli, 2022, Nature Communications.

Noninvasive Detection of Microsatellite Instability and High Tumor Mutation Burden in Cancer Patients Treated with PD-1 Blockade

David R. Riley, Samuel V. Angiuoli, V. Velculescu, 2019, Clinical Cancer Research.

Short Communication Frequent Activating Mutations of PIK3CA in Ovarian Clear Cell Carcinoma

V. Velculescu, Siân Jones, I. Shih, 2009 .

Randomized Phase II Study of Paclitaxel plus Alisertib versus Paclitaxel plus Placebo as Second-Line Therapy for SCLC: Primary and Correlative Biomarker Analyses

K. Nackaerts, Siân Jones, A. Chiang, 2020 .

Randomized Phase II Study of Paclitaxel plus Alisertib versus Paclitaxel plus Placebo as Second-Line Therapy for Small-Cell Lung Cancer: Primary and Correlative Biomarker Analyses.

K. Nackaerts, Siân Jones, A. Chiang, 2020, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Genome-wide linkage scan for colorectal cancer susceptibility genes supports linkage to chromosome 3q

B. Vogelstein, V. Velculescu, Siân Jones, 2008, BMC Cancer.

High grade serous ovarian carcinomas originate in the fallopian tube

R. Scharpf, L. Wood, V. Velculescu, 2017, Nature Communications.

Recurrent STAT6 Mutations In Follicular Lymphoma

M. Kaminski, Siân Jones, P. Ouillette, 2013 .

Somatic Mutations in the Chromatin Remodeling Gene ARID1A Occur in Several Tumor Types

Meng Li, Christine A Iacobuzio-Donahue, Bert Vogelstein, 2011, Human mutation.

Rapid recognition of aberrant dHPLC elution profiles using the Transgenomic NavigatorTM software

Siân Jones, J. Maynard, J. Cheadle, 2005, Human mutation.

SMAD4 Gene Mutations Are Associated with Poor Prognosis in Pancreatic Cancer

Giovanni Parmigiani, Amanda Blackford, Christine A Iacobuzio-Donahue, 2009, Clinical Cancer Research.

Comparative lesion sequencing provides insights into tumor evolution

Martin A. Nowak, Arne Traulsen, Niko Beerenwinkel, 2008, Proceedings of the National Academy of Sciences.

Familial and sporadic pancreatic cancer share the same molecular pathogenesis

K. Kinzler, B. Vogelstein, Siân Jones, 2015, Familial Cancer.

Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas

R. McLendon, A. Friedman, Siân Jones, 2014, Nature Genetics.

The genetic landscape of anaplastic astrocytoma

R. McLendon, A. Friedman, Siân Jones, 2013, Oncotarget.

Somatic mutations of PPP2R1A in ovarian and uterine carcinomas.

V. Velculescu, Siân Jones, I. Shih, 2011, The American journal of pathology.

Frequent activating mutations of PIK3CA in ovarian clear cell carcinoma.

V. Velculescu, Siân Jones, I. Shih, 2009, The American journal of pathology.

Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma

Tian-Li Wang, Kentaro Nakayama, Bert Vogelstein, 2010, Science.

Expression of p16 and Retinoblastoma Determines Response to CDK4/6 Inhibition in Ovarian Cancer

V. Velculescu, Siân Jones, L. Hartmann, 2011, Clinical Cancer Research.

Whole-Genome Sequencing of Salivary Gland Adenoid Cystic Carcinoma

L. Wood, K. Kinzler, B. Vogelstein, 2016, Cancer Prevention Research.

Therapeutic Potential of the Poly(ADP-ribose) Polymerase Inhibitor Rucaparib for the Treatment of Sporadic Human Ovarian Cancer

Nitin Udar, Boris Winterhoff, V. Velculescu, 2013, Molecular Cancer Therapeutics.

Activating STAT6 mutations in follicular lymphoma.

M. Kaminski, Siân Jones, P. Ouillette, 2015, Blood.

Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma

Giovanni Parmigiani, Amanda Blackford, Victor E. Velculescu, 2012, Nature Genetics.

Prevalence of deleterious ATM germline mutations in gastric cancer patients

Siân Jones, Hai Yan, Zhang Wei, 2015, Oncotarget.

Low‐grade serous carcinomas of the ovary contain very few point mutations

K. Kinzler, B. Vogelstein, V. Velculescu, 2012, The Journal of pathology.

Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients

R. Scharpf, V. Velculescu, Siân Jones, 2015, Nature Communications.

Breast and Colorectal Cancers The Consensus Coding Sequences of Human

G. Parmigiani, J. Ptak, L. Wood, 2007 .

Mutations in linker histone genes HIST1H1 B, C, D, and E; OCT2 (POU2F2); IRF8; and ARID1A underlying the pathogenesis of follicular lymphoma.

M. Kaminski, Siân Jones, P. Ouillette, 2014, Blood.

Mutations in linker histone genes HIST 1 H 1 B , C , D , and E ; OCT 2 ( POU 2 F 2 ) ; IRF 8 ; and ARID 1 A underlying the pathogenesis of follicular lymphoma

M. Kaminski, Siân Jones, P. Ouillette, 2014 .

Somatic mutations of SUZ12 in malignant peripheral nerve sheath tumors

L. Wood, E. Montgomery, K. Kinzler, 2014, Nature Genetics.

Cancer‐Associated Mutations in Endometriosis without Cancer

L. Wood, K. Kinzler, B. Vogelstein, 2017, The New England journal of medicine.

Clinical Significance of the Genetic Landscape of Pancreatic Cancer and Implications for Identification of Potential Long-term Survivors

V. Velculescu, S. Yachida, Siân Jones, 2012, Clinical Cancer Research.

Whole-Exome Sequencing of Salivary Gland Mucoepidermoid Carcinoma

Hyunseok Kang, Siân Jones, J. Bishop, 2016, Clinical Cancer Research.

Biallelic germline mutations in MYH predispose to multiple colorectal adenoma and somatic G:C-->T:A mutations.

Siân Jones, Geraint T. Williams, J. Maynard, 2002, Human molecular genetics.

Genetic mutations associated with cigarette smoking in pancreatic cancer.

G. Parmigiani, J. Cameron, K. Kinzler, 2009, Cancer research.

Personalized Genomic Analyses for Cancer Mutation Discovery and Interpretation.

Theresa Zhang, Victor E. Velculescu, Valsamo Anagnostou, 2015 .

Personalizing Cancer Treatment in the Age of Global Genomic Analyses: PALB2 Gene Mutations and the Response to DNA Damaging Agents in Pancreatic Cancer

Manuel Hidalgo, James R. Eshleman, Ralph H. Hruban, 2010, Molecular Cancer Therapeutics.

Genomic analyses of gynaecologic carcinosarcomas reveal frequent mutations in chromatin remodelling genes

Ethan Cerami, Victor E. Velculescu, Manish Shukla, 2014, Nature Communications.

Genomic and Immunological Tumor Profiling Identifies Targetable Pathways and Extensive CD8+/PDL1+ Immune Infiltration in Inflammatory Breast Cancer Tumors

V. Velculescu, Siân Jones, M. Cristofanilli, 2016, Molecular Cancer Therapeutics.

Genomic and Immunological Tumor Pro fi ling Identi fi es Targetable Pathways and Extensive CD 8 þ / PDL 1 þ Immune In fi ltration in In fl ammatory Breast Cancer Tumors

V. Velculescu, Siân Jones, M. Sausen, 2016 .

Response to Comments on "The Consensus Coding Sequences of Human Breast and Colorectal Cancers"

Giovanni Parmigiani, Victor E. Velculescu, Bert Vogelstein, 2007, Science.

Functional characterization of two human MutY homolog (hMYH) missense mutations (R227W and V232F) that lie within the putative hMSH6 binding domain and are associated with hMYH polyposis

Siân Jones, J. Cheadle, J. Sampson, 2005, Nucleic acids research.

Familial and sporadic pancreatic cancer share the same molecular pathogenesis

K. Kinzler, B. Vogelstein, Siân Jones, 2014, Familial Cancer.

Signi fi cance of the Genetic Landscape of Pancreatic Cancer and Implications for Identi fi cation of Potential Long-term Survivors

V. Velculescu, S. Yachida, Siân Jones, 2012 .

Notch1 Mutations Are Drivers of Oral Tumorigenesis

David R. Riley, Samuel V. Angiuoli, V. Velculescu, 2014, Cancer Prevention Research.

Abstract 1286: Analytical validation of an integrated next-generation sequencing pan-cancer liquid biopsy approach for detection of microsatellite instability

David R. Riley, Derrick E. Wood, Siân Jones, 2018, Bioinformatics and Systems Biology.

Regarding the Congruence Between 2 Circulating Tumor DNA Sequencing Assays.

Samuel V. Angiuoli, Siân Jones, J. White, 2018, JAMA oncology.

MutYH (MYH) and colorectal cancer.

Siân Jones, J. Cheadle, J. Sampson, 2005, Biochemical Society transactions.

Abstract 619: Identification of clinically actionable genomic alterations in the tumor and circulation of pancreatic cancer patients

V. Velculescu, Siân Jones, R. Leary, 2015 .

A method for comprehensive genomic analysis of cell-free DNA.

David R. Riley, Samuel V. Angiuoli, V. Velculescu, 2015 .

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two

Charles J. Vaske, Joe Y. Chang, Scott R. Presnell, 2016, Journal for ImmunoTherapy of Cancer.

Mutations in linker histone genes HIST1H1 B, C, D, and E; OCT2 (POU2F2); IRF8; and ARID1A underlying the pathogenesis of follicular lymphoma.

M. Kaminski, Siân Jones, P. Ouillette, 2014, Blood.

The Genetic Landscape of the Childhood Cancer Medulloblastoma

Zev A. Binder, G. Parmigiani, M. Berger, 2011, Science.

Spotlight on Clinical Response Personalizing Cancer Treatment in the Age of Global Genomic Analyses : PALB 2 Gene Mutations and the Response to DNA Damaging Agents in Pancreatic Cancer

Siân Jones, R. Hruban, J. Eshleman, 2011 .