N. Papadopoulos

发表

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

D. Busam, R. Strausberg, G. Parmigiani, 2008, Science.

Evaluating the evaluation of cancer driver genes

K. Kinzler, B. Vogelstein, R. Karchin, 2016, Proceedings of the National Academy of Sciences.

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

G. Parmigiani, K. Kinzler, B. Vogelstein, 2008, Science.

Cancer Genome Landscapes

K. Kinzler, B. Vogelstein, V. Velculescu, 2013, Science.

The Genomic Landscapes of Human Breast and Colorectal Cancers

A. Sparks, G. Parmigiani, J. Ptak, 2007, Science.

Detection and localization of surgically resectable cancers with a multi-analyte blood test

Ludmila V. Danilova, J. Vogelstein, S. Hanash, 2018, Science.

Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers

G. Parmigiani, L. Wood, K. Kinzler, 2008, Proceedings of the National Academy of Sciences.

The Consensus Coding Sequences of Human Breast and Colorectal Cancers

G. Parmigiani, J. Ptak, L. Wood, 2006, Science.

Non-invasive detection of bladder cancer through the analysis of driver gene mutations and aneuploidy

J. Ptak, K. Kinzler, B. Vogelstein, 2017, bioRxiv.

The Antisense Transcriptomes of Human Cells

K. Kinzler, B. Vogelstein, V. Velculescu, 2008, Science.

Detection and quantification of rare mutations with massively parallel sequencing

K. Kinzler, B. Vogelstein, N. Papadopoulos, 2011, Proceedings of the National Academy of Sciences.

Glucose Deprivation Contributes to the Development of KRAS Pathway Mutations in Tumor Cells

K. Kinzler, B. Vogelstein, V. Velculescu, 2009, Science.

A multimodality test to guide the management of patients with a pancreatic cyst

David L. Masica, Walter G. Park, M. Makary, 2019, Science Translational Medicine.

Detection of Chromosomal Alterations in the Circulation of Cancer Patients with Whole-Genome Sequencing

G. Parmigiani, J. Carpten, K. Kinzler, 2012, Science Translational Medicine.

Circulating tumor DNA as an early marker of therapeutic response in patients with metastatic colorectal cancer.

R. Strausberg, K. Kinzler, B. Vogelstein, 2015, Annals of oncology : official journal of the European Society for Medical Oncology.

Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer

R. Strausberg, K. Kinzler, B. Vogelstein, 2016, Science Translational Medicine.

Mutations of two P/WS homologues in hereditary nonpolyposis colon cancer

R. Fleischmann, M. Adams, J. Venter, 1994, Nature.

Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade

Ludmila V. Danilova, L. Cope, A. Zaheer, 2017, Science.

Altered Telomeres in Tumors with ATRX and DAXX Mutations

R. McLendon, K. Kinzler, C. Bettegowda, 2011, Science.

Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway

W. Hahn, B. Weir, K. Kinzler, 2012, PLoS genetics.

Heteroplasmic mitochondrial DNA mutations in normal and tumor cells

D. Dressman, K. Kinzler, B. Vogelstein, 2010, Nature.

Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1

R. Gibbs, J. Weinstein, D. Muzny, 2011, Science.

A multidimensional analysis of genes mutated in breast and colorectal cancers.

G. Parmigiani, L. Wood, K. Kinzler, 2007, Genome research.

The Genetic Landscape of the Childhood Cancer Medulloblastoma

Zev A. Binder, G. Parmigiani, M. Berger, 2011, Science.

A public database for gene expression in human cancers.

S. Altschul, R. Strausberg, R. McLendon, 1999, Cancer research.

Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer

Johannes G. Reiter, M. Nowak, L. Wood, 2017, Nature Genetics.

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

Gary L. Gallia, Arthur P. Grollman, Tian-Li Wang, 2013, Proceedings of the National Academy of Sciences.

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency.

Bert Vogelstein, Toby C. Cornish, Toby C Cornish, 2015, The New England journal of medicine.

Serial circulating tumour DNA analysis during multimodality treatment of locally advanced rectal cancer: a prospective biomarker study

K. Kinzler, P. Gibbs, M. Christie, 2018, Gut.

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

Robin J. Leach, Paul S. Meltzer, Jean Weissenbach, 1993, Cell.

Hypermutability and mismatch repair deficiency in RER+ tumor cells

Bert Vogelstein, Kenneth W. Kinzler, Paul Modrich, 1993, Cell.

Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH

Eugenia G. Giannopoulou, O. Elemento, N. Papadopoulos, 2015, Science.

Molecular Mechanisms of Cystic Neoplasia

R. Hruban, N. Papadopoulos, 2018 .

Recurrent GNAS Mutations Define an Unexpected Pathway for Pancreatic Cyst Development

A. Maitra, L. Wood, K. Kinzler, 2011, Science Translational Medicine.

Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways

A. Maitra, M. Choti, L. Wood, 2011, Proceedings of the National Academy of Sciences.

Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies

M. Choti, J. Cameron, L. Wood, 2014, Science Translational Medicine.

Evaluation of liquid from the Papanicolaou test and other liquid biopsies for the detection of endometrial and ovarian cancers

Ludmila V. Danilova, J. Ptak, K. Kinzler, 2018, Science Translational Medicine.

Mutations in CIC and FUBP1 Contribute to Human Oligodendroglioma

Yuchen Jiao, Bert Vogelstein, Chetan Bettegowda, 2011, Science.

Detection of malignant peripheral nerve sheath tumors in patients with neurofibromatosis using aneuploidy and mutation identification in plasma.

J. Ptak, C. Bettegowda, N. Papadopoulos, 2022, eLife.

Sequence and expression analysis of gaps in human chromosome 20

J. Gorodkin, N. Papadopoulos, A. Silahtaroglu, 2012, Nucleic acids research.

A combination of molecular markers and clinical features improve the classification of pancreatic cysts.

Jin-Young Jang, Amanda Blackford, Mari Mino-Kenudson, 2015, Gastroenterology.

Detection of aneuploidy in patients with cancer through amplification of long interspersed nucleotide elements (LINEs)

K. Kinzler, B. Vogelstein, R. Hruban, 2018, Proceedings of the National Academy of Sciences.

Epigenetic remodelling and dysregulation of DLGAP4 is linked with early-onset cerebellar ataxia

N. Papadopoulos, A. Silahtaroglu, Z. Tümer, 2014, Human molecular genetics.

Selected reaction monitoring approach for validating peptide biomarkers

Tyler M. Tomita, J. Vogelstein, K. Kinzler, 2017, Proceedings of the National Academy of Sciences.

Transcriptional control of the chicken cardiac myosin light-chain gene is mediated by two AT-rich cis-acting DNA elements and binding of serum response factor

N. Papadopoulos, M. Crow, 1993, Molecular and cellular biology.

APC gene mutations in the mutation cluster region are rare in esophageal cancers.

K. Kinzler, N. Papadopoulos, S. Powell, 1994, Gastroenterology.

Assignment of the Human p27Kipl Gene to 12pl3 and Its Analysis in Leukemias1

James M. Roberts, K. Kinzler, B. Vogelstein, 1995 .

Deletion ofpl 6 and pl 5 Genes in Brain Tumors 1

D. Bigner, N. Papadopoulos, J. Jen, 2006 .

Direct Detection and Quantification of Neo-antigens

Bert, K. Kinzler, N. Papadopoulos, 2019 .

Direct Detection and Quantification of Neoantigens

K. Kinzler, B. Vogelstein, N. Papadopoulos, 2019, Cancer Immunology Research.

Lavage of the Uterine Cavity for Molecular Detection of Müllerian Duct Carcinomas: A Proof-of-Concept Study

K. Kinzler, B. Vogelstein, L. Diaz, 2015, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints

K. Kinzler, B. Vogelstein, J. Taube, 2015, Journal of Immunotherapy for Cancer.

Circulating tumor DNA (ctDNA) as a marker of recurrence risk in stage II colon cancer (CC).

R. Strausberg, K. Kinzler, B. Vogelstein, 2014 .

Seq-ing the SINEs of central nervous system tumors in cerebrospinal fluid

Christopher M. Jackson, J. Ptak, K. Kinzler, 2022, medRxiv.

High prevalence of TERT promoter mutations in micropapillary urothelial carcinoma

K. Kinzler, B. Vogelstein, N. Papadopoulos, 2016, Virchows Archiv.

Spectrum of genetic mutations in de novo PUNLMP of the urinary bladder

K. Kinzler, B. Vogelstein, N. Papadopoulos, 2017, Virchows Archiv.

Detection of TERT promoter mutations in primary adenocarcinoma of the urinary bladder.

K. Kinzler, B. Vogelstein, N. Papadopoulos, 2016, Human pathology.

Performance of novel non-invasive urine assay UroSEEK in cohorts of equivocal urine cytology

K. Kinzler, B. Vogelstein, N. Papadopoulos, 2019, Virchows Archiv.

Abstract 5606: Detection of circulating tumor DNA in early and late stage human malignancies

K. Kinzler, C. Bettegowda, B. Vogelstein, 2014 .

Somatic Mutations in the Chromatin Remodeling Gene ARID1A Occur in Several Tumor Types

Meng Li, Christine A Iacobuzio-Donahue, Bert Vogelstein, 2011, Human mutation.

Genomic organization of the human PMS2 gene family.

K. Kinzler, B. Vogelstein, N. Papadopoulos, 1995, Genomics.

Isaac Kinde Endometrial Cancers Evaluation of DNA from the Papanicolaou Test to Detect Ovarian

James R. Eshleman, Yuxuan Wang, Bert Vogelstein, 2013 .

Conversion of diploidy to haploidy - Individuals susceptible to multigene disorders may now be spotted more easily.

A. Chapelle, K. Kinzler, B. Vogelstein, 2000 .

The potential of circulating tumor DNA (ctDNA) to guide adjuvant chemotherapy decision making in locally advanced rectal cancer (LARC).

K. Kinzler, B. Vogelstein, P. Gibbs, 2017 .

Heterogeneityof LipoproteinElectrophoreticPatternsin PatientswithType HaHyperlipoproteinemia

N. Papadopoulos, R. Gregg, H. Brewer, 2004 .

Intratumoral injection of Clostridium novyi-NT spores induces antitumor responses

Robert S. Benjamin, Ravi Murthy, Bert Vogelstein, 2014, Science Translational Medicine.

Comparative genomic analysis of esophageal adenocarcinoma and squamous cell carcinoma.

Yuchen Jiao, Yuxuan Wang, Bert Vogelstein, 2012, Cancer discovery.

Identification of novel noncoding transcripts in telomerase-negative yeast using RNA-seq

N. Papadopoulos, D. Zappulla, David C. Zappulla, 2016, Scientific Reports.

Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries

Stephanie A. Bien, Anna C. Wu, Aung Ko Win, 2022, Nature Genetics.

Sensitive digital quantification of DNA methylation in clinical samples

S. Goodman, K. Kinzler, B. Vogelstein, 2009, Nature Biotechnology.

High prevalence of TERT promoter mutations in primary squamous cell carcinoma of the urinary bladder

K. Kinzler, B. Vogelstein, N. Papadopoulos, 2016, Modern Pathology.

Familial and sporadic pancreatic cancer share the same molecular pathogenesis

K. Kinzler, B. Vogelstein, Siân Jones, 2015, Familial Cancer.

CACP, encoding a secreted proteoglycan, is mutated in camptodactyly-arthropathy-coxa vara-pericarditis syndrome

S. Schwartz, J. Carpten, J. Trent, 1999, Nature Genetics.

The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints

K. Kinzler, B. Vogelstein, J. Taube, 2015, Journal of Immunotherapy for Cancer.

Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas

T. Pawlik, L. Wood, K. Kinzler, 2013, Nature Genetics.

Disruption of a self-amplifying catecholamine loop reduces cytokine release syndrome

K. Kinzler, B. Vogelstein, G. Riggins, 2018, Nature.

Eradication of metastatic mouse cancers resistant to immune checkpoint blockade by suppression of myeloid-derived cells

K. Kinzler, B. Vogelstein, L. Diaz, 2014, Journal of Immunotherapy for Cancer.

Whole‐exome sequencing of pancreatic neoplasms with acinar differentiation

J. Herman, L. Wood, K. Kinzler, 2014, The Journal of pathology.

Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas

R. McLendon, A. Friedman, K. Kinzler, 2012, Oncotarget.

Detection of tumor-derived DNA in cerebrospinal fluid of patients with primary tumors of the brain and spinal cord

J. Ptak, K. Kinzler, C. Bettegowda, 2015, Proceedings of the National Academy of Sciences.

Targeting loss of heterozygosity for cancer-specific immunotherapy

K. Kinzler, C. Bettegowda, B. Vogelstein, 2021, Proceedings of the National Academy of Sciences.

Mutation of the TERT promoter, switch to active chromatin, and monoallelic TERT expression in multiple cancers

B. Vogelstein, T. Cech, N. Papadopoulos, 2015, Genes & development.

DAXX/ATRX, MEN1, and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors

Michael A. Choti, Yuchen Jiao, Victor E. Velculescu, 2011, Science.

Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma

Tian-Li Wang, Kentaro Nakayama, Bert Vogelstein, 2010, Science.

Multicancer early detection test: Preclinical, translational, and clinical evidence–generation plan and provocative questions

N. Papadopoulos, Minetta C. Liu, E. Hawk, 2022, Cancer.

Exomic analysis of myxoid liposarcomas, synovial sarcomas, and osteosarcomas

Yuchen Jiao, Jinyong Luo, Tong-Chuan He, 2014, Genes, chromosomes & cancer.

Whole-Genome Sequencing of Salivary Gland Adenoid Cystic Carcinoma

L. Wood, K. Kinzler, B. Vogelstein, 2016, Cancer Prevention Research.

The molecular basis of Turcot's syndrome.

K. Kinzler, B. Vogelstein, Z. Cohen, 1995, The New England journal of medicine.

Analysis of mismatch repair genes in hereditary non–polyposis colorectal cancer patients

K. Kinzler, N. Papadopoulos, J. Jass, 1996, Nature Medicine.

Feasibility of blood testing combined with PET-CT to screen for cancer and guide intervention

D. Ledbetter, K. Kinzler, C. Bettegowda, 2020, Science.

Mutational Signature of Aristolochic Acid Exposure as Revealed by Whole-Exome Sequencing

K. Kinzler, B. Vogelstein, R. Karchin, 2013, Science Translational Medicine.

Precancerous neoplastic cells can move through the pancreatic ductal system

Johannes G. Reiter, Jeffrey M. Gerold, M. Nowak, 2018, Nature.

Persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1

Ludmila V. Danilova, L. Cope, K. Kinzler, 2019, Journal of Immunotherapy for Cancer.

Genetic instability occurs in the majority of young patients with colorectal cancer

B. Vogelstein, N. Papadopoulos, J. Jen, 1995, Nature Medicine.

Tumor DNA as a Cancer Biomarker through the Lens of Colorectal Neoplasia

K. Kinzler, N. Papadopoulos, J. Cohen, 2020, Cancer Epidemiology, Biomarkers & Prevention.

Bisulfite-converted duplexes for the strand-specific detection and quantification of rare mutations

K. Kinzler, B. Vogelstein, N. Papadopoulos, 2017, Proceedings of the National Academy of Sciences.

Generation of MANAbodies specific to HLA-restricted epitopes encoded by somatically mutated genes

K. Kinzler, B. Vogelstein, L. Diaz, 2015, Proceedings of the National Academy of Sciences.

Progression model of prostate cancer.

N. Papadopoulos, T. Almeida, 2003, Methods in molecular biology.

Deletion of p16 and p15 genes in brain tumors.

K. Kinzler, B. Vogelstein, D. Bigner, 1994, Cancer research.

APC/CTNNB1 (β‐catenin) pathway alterations in human prostate cancers

Kenneth Pienta, K. Pienta, M. Rubin, 2002 .

APC/CTNNB1 (beta-catenin) pathway alterations in human prostate cancers.

K. Pienta, M. Rubin, N. Papadopoulos, 2002, Genes, chromosomes & cancer.

Serial assessment of human tumor burdens in mice by the analysis of circulating DNA.

K. Kinzler, B. Vogelstein, V. Velculescu, 2007, Cancer research.

Analysis of Circulating DNA Serial Assessment of Human Tumor Burdens in Mice by the

K. Kinzler, B. Vogelstein, V. Velculescu, 2007 .

Massively Parallel Sequencing of Esophageal Brushings Enables an Aneuploidy-Based Classification of Patients with Barrett's Esophagus.

K. Kinzler, C. Bettegowda, B. Vogelstein, 2021, Gastroenterology.

Exomic Sequencing of Four Rare Central Nervous System Tumor Types

Gary L. Gallia, Yuchen Jiao, Yuxuan Wang, 2013, Oncotarget.

Frequent HIN-1 promoter methylation and lack of expression in multiple human tumor types.

M. Meyerson, T. Stamey, M. Loda, 2004, Molecular cancer research : MCR.

ATM mutations in patients with hereditary pancreatic cancer.

Yuchen Jiao, Michele L Cote, Bert Vogelstein, 2012, Cancer discovery.

Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer.

J. Potash, P. Zandi, L. Wood, 2016, Cancer discovery.

Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma

Giovanni Parmigiani, Amanda Blackford, Victor E. Velculescu, 2012, Nature Genetics.

Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas

K. Kinzler, C. Bettegowda, B. Vogelstein, 2015, Science Translational Medicine.

Whole-Exome Sequencing Analyses of Inflammatory Bowel Disease-Associated Colorectal Cancers.

M. Pittman, K. Kinzler, B. Vogelstein, 2016, Gastroenterology.

Leary Patients with Whole-Genome Sequencing Detection of Chromosomal Alterations in the Circulation of Cancer

Shaughnessy, G. Parmigiani, J. Carpten, 2012 .

Low‐grade serous carcinomas of the ovary contain very few point mutations

K. Kinzler, B. Vogelstein, V. Velculescu, 2012, The Journal of pathology.

Paradoxical inhibition of solid tumor cell growth by bcl2.

K. Kinzler, B. Vogelstein, N. Papadopoulos, 1994, Cancer research.

Genetic inactivation of AKT1, AKT2, and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation

K. Kinzler, B. Vogelstein, V. Velculescu, 2010, Proceedings of the National Academy of Sciences.

Absence of mutations in DICE1/DDX26 gene in human cancer cell lines with frequent 13q14 deletions.

N. Papadopoulos, M. Hernández, T. Almeida, 2005, Cancer genetics and cytogenetics.

IgH gene rearrangements as plasma biomarkers in Non-Hodgkin's Lymphoma patients

K. Kinzler, B. Vogelstein, L. Diaz, 2011, Oncotarget.

The role of companion diagnostics in the development and use of mutation-targeted cancer therapies

Bert Vogelstein, K. Kinzler, B. Vogelstein, 2006, Nature Biotechnology.

Combined circulating tumor DNA and protein biomarker-based liquid biopsy for the earlier detection of pancreatic cancers

M. Makary, S. Hanash, Song-Cheol Kim, 2017, Proceedings of the National Academy of Sciences.

Association of the Autoimmune Disease Scleroderma with an Immunologic Response to Cancer

Yuchen Jiao, Ami A. Shah, Bert Vogelstein, 2014, Science.

Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens

Michelle S. Miller, K. Kinzler, C. Bettegowda, 2021, Nature Communications.

Genome-wide quantification of rare somatic mutations in normal human tissues using massively parallel sequencing

Arthur P. Grollman, Bert Vogelstein, Kenneth W. Kinzler, 2016, Proceedings of the National Academy of Sciences.

APC mutations in colorectal tumors with mismatch repair deficiency.

K. Kinzler, B. Vogelstein, N. Papadopoulos, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Breast and Colorectal Cancers The Consensus Coding Sequences of Human

G. Parmigiani, J. Ptak, L. Wood, 2007 .

TERT promoter mutations occur early in urothelial neoplasia and are biomarkers of early disease and disease recurrence in urine.

K. Kinzler, B. Vogelstein, R. Hruban, 2013, Cancer research.

Molecular determinants of dysplasia in colorectal lesions.

K. Kinzler, B. Vogelstein, N. Papadopoulos, 1994, Cancer research.

Mutations of GTBP in genetically unstable cells.

K. Kinzler, B. Vogelstein, N. Papadopoulos, 1995, Science.

Assignment of the human p27Kip1 gene to 12p13 and its analysis in leukemias.

James M. Roberts, B. Trask, K. Kinzler, 1995, Cancer research.

Detection of malignant peripheral nerve sheath tumors in patients with neurofibromatosis using aneuploidy and mutation identification in plasma

J. Ptak, C. Bettegowda, N. Papadopoulos, 2021, medRxiv.

Ultrasensitive detection of tumor‐specific mutations in saliva of patients with oral cavity squamous cell carcinoma

C. Bettegowda, N. Papadopoulos, Radhakrishna Bettadapura, 2020, Cancer.

Applications of liquid biopsies for cancer

K. Kinzler, C. Bettegowda, B. Vogelstein, 2019, Science Translational Medicine.

Prognostic Potential of Circulating Tumor DNA Measurement in Postoperative Surveillance of Nonmetastatic Colorectal Cancer.

J. Ptak, K. Kinzler, B. Vogelstein, 2019, JAMA oncology.

Somatic mutations of SUZ12 in malignant peripheral nerve sheath tumors

L. Wood, E. Montgomery, K. Kinzler, 2014, Nature Genetics.

Conversion of diploidy to haploidy

James R. Eshleman, Bert Vogelstein, Kenneth W. Kinzler, 2000, Nature.

Aristolochic Acid in the Etiology of Renal Cell Carcinoma

K. Kinzler, B. Vogelstein, N. Papadopoulos, 2016, Cancer Epidemiology, Biomarkers & Prevention.

Targeting a neoantigen derived from a common TP53 mutation

Michelle S. Miller, K. Kinzler, C. Bettegowda, 2021, Science.

Cancer‐Associated Mutations in Endometriosis without Cancer

L. Wood, K. Kinzler, B. Vogelstein, 2017, The New England journal of medicine.

Colorectal Cancer Genome and Its Implications

N. Papadopoulos, 2013 .

Pembrolizumab for patients with leptomeningeal metastasis from solid tumors: efficacy, safety, and cerebrospinal fluid biomarkers

A. Venkatesan, K. Kinzler, C. Bettegowda, 2021, Journal for ImmunoTherapy of Cancer.

FAST-SeqS: A Simple and Efficient Method for the Detection of Aneuploidy by Massively Parallel Sequencing

K. Kinzler, B. Vogelstein, N. Papadopoulos, 2012, PloS one.

A panel of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53

K. Kinzler, B. Vogelstein, L. Diaz, 2009, Proceedings of the National Academy of Sciences.

Complement c5a receptor facilitates cancer metastasis by altering T-cell responses in the metastatic niche.

K. Kinzler, B. Vogelstein, E. Fishman, 2014, Cancer research.

Molecular basis of HNPCC: Mutations of MMR genes

N. Papadopoulos, A. Lindblom, 1997, Human mutation.

Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival

Richard T. Barfield, David A. Drew, Lincoln D. Stein, 2020, Nature Communications.

The potential of circulating tumor DNA (ctDNA) to reshape the design of clinical trials testing adjuvant therapy in patients with early stage cancers.

R. Strausberg, K. Kinzler, B. Vogelstein, 2016 .

Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma

Michael A Choti, Bert Vogelstein, Timothy M Pawlik, 2011, Nature Genetics.

Incidence and Distribution of UroSEEK Gene Panel in a Multi-institutional Cohort of Bladder Urothelial Carcinoma

K. Kinzler, B. Vogelstein, N. Papadopoulos, 2019, Modern Pathology.

Targeted sequencing of plasmacytoid urothelial carcinoma reveals frequent TERT promoter mutations.

K. Kinzler, B. Vogelstein, N. Papadopoulos, 2019, Human pathology.

Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy

Ludmila V. Danilova, J. Ptak, K. Kinzler, 2018, eLife.

Conversion technology and its role in genetic testing of inherited diseases

N. Papadopoulos, 2003, Expert review of molecular diagnostics.

Conversion technology and cancer predispositions.

N. Papadopoulos, 2003, Methods in molecular biology.

Characterization of a t(5;8)(q31;q21) translocation in a patient with mental retardation and congenital heart disease: implications for involvement of RUNX1T1 in human brain and heart development

N. Papadopoulos, Z. Tümer, N. Tommerup, 2009, European Journal of Human Genetics.

Lynch syndrome (hereditary nonpolyposis colorectal cancer) diagnostics.

K. Kinzler, B. Vogelstein, N. Papadopoulos, 2007, Journal of the National Cancer Institute.

University of Southern Denmark Evaluation of liquid from the Papanicolaou test and other liquid biopsies for the detection of endometrial and ovarian cancers

J. Ptak, K. Kinzler, B. Vogelstein, 2018 .

Limited detection of IgH gene rearrangements in plasma of patients with primary central nervous system lymphoma

K. Kinzler, B. Vogelstein, N. Papadopoulos, 2013, Journal of Neuro-Oncology.

Global identification of MLL2-targeted loci reveals MLL2’s role in diverse signaling pathways

R. McLendon, Hai Yan, D. Bigner, 2012, Proceedings of the National Academy of Sciences.

Alpha-1 adrenergic receptor antagonists for preventing acute respiratory distress syndrome and death from cytokine storm syndrome.

E. Stuart, S. Athey, J. Vogelstein, 2020, ArXiv.

Genomic analysis identifies frequent deletions of Dystrophin in olfactory neuroblastoma

Zev A. Binder, K. Kinzler, C. Bettegowda, 2018, Nature Communications.

Alpha-1 adrenergic receptor antagonists to prevent hyperinflammation and death from lower respiratory tract infection

E. Stuart, S. Athey, J. Vogelstein, 2020, eLife.

Preventing cytokine storm syndrome in COVID-19 using α-1 adrenergic receptor antagonists.

S. Athey, J. Vogelstein, B. Mensh, 2020, The Journal of clinical investigation.

Germline missense mutations in mismatch-repair genes and genetic testing for HNPCC

N. Papadopoulos, 2007 .

Molecular Genetics of Neuroendocrine Tumors

R. Hruban, N. Papadopoulos, 2018 .

Inpatient Administration of Alpha-1-Adrenergic Receptor Blocking Agents Reduces Mortality in Male COVID-19 Patients

J. Vogelstein, C. Bettegowda, M. Konig, 2022, Frontiers in Medicine.

Pathophysiology of ctDNA Release into the Circulation and Its Characteristics: What Is Important for Clinical Applications.

N. Papadopoulos, 2020, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.

Bispecific antibodies targeting mutant RAS neoantigens

Michelle S. Miller, K. Kinzler, C. Bettegowda, 2021, Science Immunology.

A novel approach for selecting combination clinical markers of pathology applied to a large retrospective cohort of surgically resected pancreatic cysts

Young Joon Ahn, Elliot K. Fishman, Yuxuan Wang, 2017, J. Am. Medical Informatics Assoc..

Genetic Classification of Gliomas: Refining Histopathology.

L. Diaz, N. Papadopoulos, M. Foote, 2015, Cancer cell.

Conversion analysis for mutation detection in MLH1 and MSH2 in patients with colorectal cancer.

D. Seminara, J. Hopper, S. Thibodeau, 2005, JAMA.

Somatic mutations in the transcriptional corepressor gene BCORL1 in adult acute myelogenous leukemia.

K. Kinzler, B. Vogelstein, N. Papadopoulos, 2011, Blood.

Mutant proteins as cancer-specific biomarkers

K. Kinzler, B. Vogelstein, R. Hruban, 2011, Proceedings of the National Academy of Sciences.

Exomic sequencing of medullary thyroid cancer reveals dominant and mutually exclusive oncogenic mutations in RET and RAS.

L. Wood, K. Kinzler, C. Bettegowda, 2013, The Journal of clinical endocrinology and metabolism.

Sequence analysis of 515 kinase genes in chronic lymphocytic leukemia

K. Kinzler, B. Vogelstein, V. Velculescu, 2011, Leukemia.

Prognostic significance of postsurgery circulating tumor DNA in nonmetastatic colorectal cancer: Individual patient pooled analysis of three cohort studies

J. Ptak, K. Kinzler, B. Vogelstein, 2020, International journal of cancer.

An engineered antibody fragment targeting mutant β-catenin via major histocompatibility complex I neoantigen presentation

Michelle S. Miller, K. Kinzler, B. Vogelstein, 2019, The Journal of Biological Chemistry.

TCR β chain–directed bispecific antibodies for the treatment of T cell cancers

K. Kinzler, C. Bettegowda, B. Vogelstein, 2021, Science Translational Medicine.

Ras/Raf and Their Influence in Glycolysis in Colon Cancer

N. Papadopoulos, F. Bunz, 2012 .

Disruption of a self-amplifying catecholamine loop reduces cytokine release syndrome

K. Kinzler, B. Vogelstein, G. Riggins, 2018, Nature.

An isogenic cell line panel for sequence-based screening of targeted anticancer drugs

K. Kinzler, C. Bettegowda, B. Vogelstein, 2021, bioRxiv.

Diagnostic potential of tumor DNA from ovarian cyst fluid

K. Kinzler, B. Vogelstein, L. Diaz, 2016, eLife.

The rapid and highly parallel identification of antibodies with defined biological activities by SLISY

K. Kinzler, C. Bettegowda, B. Vogelstein, 2023, Nature Communications.

Clinical, genomic, and metagenomic characterization of oral tongue squamous cell carcinoma in patients who do not smoke

M. Meyerson, J. Derisi, L. Wood, 2015, Head & neck.

Response to Comments on "The Consensus Coding Sequences of Human Breast and Colorectal Cancers"

Giovanni Parmigiani, Victor E. Velculescu, Bert Vogelstein, 2007, Science.

Monoallelic mutation analysis (MAMA) for identifying germline mutations

K. Kinzler, B. Vogelstein, N. Papadopoulos, 1995, Nature Genetics.

Familial and sporadic pancreatic cancer share the same molecular pathogenesis

K. Kinzler, B. Vogelstein, Siân Jones, 2014, Familial Cancer.

Intraductal papillary mucinous neoplasm in a neonate with congenital hyperinsulinism and a de novo germline SKIL gene mutation.

K. Kinzler, B. Vogelstein, R. Hruban, 2015, Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].

Very Long-term Survival Following Resection for Pancreatic Cancer Is Not Explained by Commonly Mutated Genes: Results of Whole-Exome Sequencing Analysis

L. Wood, K. Kinzler, B. Vogelstein, 2015, Clinical Cancer Research.

Assessing aneuploidy with repetitive element sequencing

Tian-Li Wang, Rachel Karchin, Robert E. Schoen, 2019, Proceedings of the National Academy of Sciences.

Analysis of masked mutations in familial adenomatous polyposis.

K. Kinzler, B. Vogelstein, S. Gruber, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Molecular and Pathology Features of Colorectal Tumors and Patient Outcomes Are Associated with Fusobacterium nucleatum and Its Subspecies animalis

E. Mardis, T. Hudson, V. Ferretti, 2021, Cancer Epidemiology, Biomarkers & Prevention.

Common occurrence of APC and K-ras gene mutations in the spectrum of colitis-associated neoplasias.

K. Kinzler, N. Papadopoulos, C. Caldas, 1995, Gastroenterology.

Non-invasive detection of upper tract urothelial carcinomas through the analysis of driver gene mutations and aneuploidy in urine

Ludmila V. Danilova, J. Ptak, K. Kinzler, 2017, bioRxiv.

Microsatellite instability (MSI) in non-colonic, non-HNPCC tumors: 'instable' evidence?

N. Papadopoulos, 1999, Annals of oncology : official journal of the European Society for Medical Oncology.

Detection of Somatic TP53 Mutations in Tampons of Patients With High-Grade Serous Ovarian Cancer

K. Kinzler, B. Vogelstein, L. Diaz, 2014, Obstetrics and gynecology.

Evaluation of DNA from the Papanicolaou Test to Detect Ovarian and Endometrial Cancers

K. Kinzler, C. Bettegowda, B. Vogelstein, 2013, Science Translational Medicine.

Detection of rare mutations, copy number alterations, and methylation in the same template DNA molecules.

J. Ptak, K. Kinzler, C. Bettegowda, 2023, Proceedings of the National Academy of Sciences of the United States of America.

Detection of low-frequency DNA variants by targeted sequencing of the Watson and Crick strands

J. Ptak, K. Kinzler, B. Vogelstein, 2021, Nature Biotechnology.

Targeting the catecholamine-cytokine axis to prevent SARS-CoV-2 cytokine storm syndrome

S. Athey, J. Vogelstein, B. Mensh, 2020, medRxiv.

Genomic analysis identifies frequent deletions of Dystrophin in olfactory neuroblastoma

Zev A. Binder, K. Kinzler, C. Bettegowda, 2018, Nature Communications.

The potential role of circulating tumor DNA (ctDNA) in the further investigation of colorectal cancer patients with nonspecific findings on standard investigations

K. Kinzler, B. Vogelstein, P. Gibbs, 2019, International journal of cancer.

Correction: Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy

J. Ptak, K. Kinzler, B. Vogelstein, 2018, eLife.

Serial circulating tumor DNA (ctDNA) analysis as a prognostic marker and a real-time indicator of adjuvant chemotherapy (CT) efficacy in stage III colon cancer (CC).

K. Kinzler, B. Vogelstein, P. Gibbs, 2018 .

Circulating tumor DNA as a prognostic biomarker in early stage pancreatic cancer.

K. Kinzler, B. Vogelstein, P. Gibbs, 2018 .

Serial circulating tumor DNA (ctDNA) and recurrence risk in patients (pts) with resectable colorectal liver metastasis (CLM).

R. Strausberg, K. Kinzler, B. Vogelstein, 2016 .

Mutation of a mutL homolog in hereditary colon cancer.

R. Fleischmann, M. Adams, J. Venter, 1994, Science.

Alpha-1 adrenergic receptor antagonists prevent acute respiratory distress syndrome and death: implications for Coronavirus disease 2019

S. Athey, J. Vogelstein, B. Mensh, 2020 .

Abstract IA04: ATRX mutations in human carcinogenesis

N. Papadopoulos, 2013 .

Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen

K. Kinzler, C. Bettegowda, B. Vogelstein, 2023, Nature communications.

A retrospective clinical study supporting the rationale for trials of Alpha-1 Adrenoreceptor Antagonists to prevent cytokine storm and severe COVID-19

S. Athey, J. Vogelstein, B. Mensh, 2020 .

The Liquid Biopsy Consortium: Challenges and opportunities for early cancer detection and monitoring

Michelle A. Garlin, C. Bettegowda, N. Papadopoulos, 2023, Cell reports. Medicine.

ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1

K. Kinzler, C. Bettegowda, B. Vogelstein, 2023, bioRxiv.

Extrinsic and intrinsic preanalytical variables affecting liquid biopsy in cancer.

C. Bettegowda, N. Papadopoulos, L. Balaj, 2023, Cell Reports Medicine.

Altered Telomeres in Tumors with ATRX and DAXX Mutations

R. McLendon, K. Kinzler, C. Bettegowda, 2011, Science.

The Antisense Transcriptomes of Human Cells

K. Kinzler, B. Vogelstein, V. Velculescu, 2008, Science.

Eradication of metastatic mouse cancers resistant to immune checkpoint blockade by suppression of myeloid-derived cells

K. Kinzler, B. Vogelstein, N. Papadopoulos, 2014, Proceedings of the National Academy of Sciences.

Detection of TERT promoter mutations in primary adenocarcinoma of the urinary bladder.

K. Kinzler, B. Vogelstein, N. Papadopoulos, 2016, Human pathology.

Eradication of metastatic mouse cancers resistant to immune checkpoint blockade by suppression of myeloid-derived cells

K. Kinzler, B. Vogelstein, N. Papadopoulos, 2014, Proceedings of the National Academy of Sciences.

Correction for Genetic inactivation of AKT1, AKT2, and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation

G M Anantharamaiah, K. Kinzler, V. Velculescu, 2010 .

Whole‐exome sequencing of pancreatic neoplasms with acinar differentiation

J. Herman, L. Wood, K. Kinzler, 2014, The Journal of pathology.

The Genetic Landscape of the Childhood Cancer Medulloblastoma

Zev A. Binder, G. Parmigiani, M. Berger, 2011, Science.

Precancerous neoplastic cells can move through the pancreatic ductal system

Johannes G. Reiter, Jeffrey M. Gerold, M. Nowak, 2018, Nature.

Whole-Exome Sequencing Analyses of Inflammatory Bowel Disease-Associated Colorectal Cancers.

M. Pittman, K. Kinzler, B. Vogelstein, 2016, Gastroenterology.

Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways

M. Choti, L. Wood, K. Kinzler, 2011, Proceedings of the National Academy of Sciences.

Heteroplasmic mitochondrial DNA mutations in normal and tumor cells

D. Dressman, K. Kinzler, B. Vogelstein, 2010, Nature.

Cancer therapy with antibodies.

C. Bettegowda, M. Konig, N. Papadopoulos, 2024, Nature reviews. Cancer.

Exomic Sequencing of Four Rare Central Nervous System Tumor Types

Zev A. Binder, R. McLendon, L. Wood, 2013, Oncotarget.

Genetic landscape of extreme responders with anaplastic oligodendroglioma

M. Mehta, K. Kinzler, C. Bettegowda, 2017, Oncotarget.

Genetic Classification of Gliomas: Refining Histopathology.

L. Diaz, N. Papadopoulos, M. Foote, 2015, Cancer cell.

Preclinical studies show that Co-STARs combine the advantages of chimeric antigen and T cell receptors for the treatment of tumors with low antigen densities

Michelle S. Miller, K. Kinzler, C. Bettegowda, 2024, Science Translational Medicine.

Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape

K. Kinzler, C. Bettegowda, N. Papadopoulos, 2023, bioRxiv.

Machine learning to detect the SINEs of cancer

K. Kinzler, N. Papadopoulos, M. Goggins, 2024, Science Translational Medicine.

Exomic analysis of myxoid liposarcomas, synovial sarcomas, and osteosarcomas

L. Wood, K. Kinzler, B. Vogelstein, 2014, Genes, chromosomes & cancer.

Multiyear Clinical Outcomes of Cancers Diagnosed Following Detection by a Blood-Based Multicancer Early Detection Test

N. Papadopoulos, A. Lennon, Zachary M. Salvati, 2024, Cancer prevention research.