A. Pardi

发表

Chemical shift anisotropy of imino 15N nuclei in Watson-Crick base pairs from magic angle spinning liquid crystal NMR and nuclear spin relaxation.

A. Bax, A. Grishaev, L. Yao, 2009, Journal of the American Chemical Society.

High-resolution molecular discrimination by RNA.

A. Pardi, R. Jenison, B. Polisky, 1994, Science.

A network of heterogeneous hydrogen bonds in GNRA tetraloops.

H. Heus, A. Pardi, E. Moors, 1996, Journal of molecular biology.

Interlocking structural motifs mediate molecular discrimination by a theophylline-binding RNA

Grant R. Zimmermann, A. Pardi, G. Zimmermann, 1997, Nature Structural Biology.

Tunable alignment of macromolecules by filamentous phage yields dipolar coupling interactions

L. Mueller, A. Pardi, M. Hansen, 1998, Nature Structural Biology.

Hydrogen bond length and proton NMR chemical shifts in proteins

A. Pardi, G. Wagner, K. Wuethrich, 1983 .

Calibration of the angular dependence of the amide proton-Cα proton coupling constants, 3JHNα, in a globular protein: Use of 3JHNα for identification of helical secondary structure

M. Billeter, K. Wüthrich, A. Pardi, 1984 .

Solution structure of bovine neutrophil beta-defensin-12: the peptide fold of the beta-defensins is identical to that of the classical defensins.

A. Pardi, G. Zimmermann, M. Selsted, 1995, Biochemistry.

RNA aptamers to the peptidyl transferase inhibitor chloramphenicol.

L. Gold, D. H. Burke, A. Pardi, 1997, Chemistry & biology.

Structure and dynamics of the iron responsive element RNA: implications for binding of the RNA by iron regulatory binding proteins.

R D Klausner, R. Klausner, A. Pardi, 1997, Journal of molecular biology.

NMR spectra of exchangeable protons using uniform excitation solvent suppression pulse sequences

A. Pardi, Chuan Wang, 1987 .

Structure-Based Assignment of Ile, Leu, and Val Methyl Groups in the Active and Inactive Forms of the Mitogen-Activated Protein Kinase Extracellular Signal-Regulated Kinase 2.

A. Pardi, N. Ahn, Yao Xiao, 2015, Biochemistry.

Flexibility in the Periplasmic Domain of BamA Is Important for Function.

A. Pardi, M. Sousa, P. A. Doerner, 2017, Structure.

Structure and flexibility of the complete periplasmic domain of BamA: the protein insertion machine of the outer membrane.

A. Pardi, M. Sousa, Lisa R. Warner, 2010, Structure.

The Effects of Various Grades of Graphite Electrodes on the Carrier Distillation of Impurities in U3O8

A. Pardi, C. E. Pepper, M. Atwell, 1963 .

Kinetics for exchange of the imino protons of the d(C-G-C-G-A-A-T-T-C-G-C-G) double helix in complexes with the antibiotics netropsin and/or actinomycin.

I. Tinoco, D. Patel, A. Pardi, 1983, Biochemistry.

Kinetics for exchange of imino protons in deoxyribonucleic acid, ribonucleic acid, and hybrid oligonucleotide helices.

I. Tinoco, A. Pardi, 1982, Biochemistry.

Comparative study of ribonucleotides, deoxyribonucleotides, and hybrid oligonucleotide helixes by nuclear magnetic resonance

I. Tinoco, A. Pardi, F. H. Martin, 1981 .

Determination of Protein Structures in Solution Using Nmr Data and Impact

R. Levy, A. Pardi, D. Kitchen, 1988 .

Solution structure of the calcium channel antagonist omega-conotoxin GVIA.

A. Pardi, W. Metzler, J. Skalicky, 1993, Protein science : a publication of the Protein Society.

NMR studies of defensin antimicrobial peptides. 2. Three-dimensional structures of rabbit NP-2 and human HNP-1.

A. Pardi, M. Selsted, Ping F. Yip, 1992, Biochemistry.

Solution structures of defensins: Naturally occurring peptide antibiotics

A. Pardi, A. Bach, D. Hare, 1988 .

Efficient detection of hydrogen bonds in dynamic regions of RNA by sensitivity-optimized NMR pulse sequences.

A. Pardi, B. Simon, M. Sattler, 2013, Angewandte Chemie.

NMR studies of defensin antimicrobial peptides. 1. Resonance assignment and secondary structure determination of rabbit NP-2 and human HNP-1.

A. Pardi, M. Selsted, X. Zhang, 1992, Biochemistry.

Solution structures of the rabbit neutrophil defensin NP-5.

A. Pardi, M. Selsted, D. Bassolino, 1988, Journal of molecular biology.

Structure and dynamics of the neutrophil defensins NP‐2, NP‐5, and HNP‐1: NMR studies of amide hydrogen exchange kinetics

A. Pardi, M. Selsted, J. Skalicky, 1994, Proteins.

Kinetics for exchange of imino protons in the d(C-G-C-G-A-A-T-T-C-G-C-G) double helix and in two similar helices that contain a G . T base pair, d(C-G-T-G-A-A-T-T-C-G-C-G), and an extra adenine, d(C-G-C-A-G-A-A-T-T-C-G-C-G).

I. Tinoco, D. Patel, A. Pardi, 1982, Biochemistry.

DNA conformation, dynamics, and interactions in solution.

D. Patel, A. Pardi, K. Itakura, 1982, Science.

SEQUENTIAL ASSIGNMENTS FOR THE HYDROGEN AND PHOSPHORUS-31 ATOMS IN THE BACKBONE OF OLIGONUCLEOTIDES BY TWO-DIMENSIONAL NUCLEAR MAGNETIC RESONANCE

G. Wider, A. Pardi, R. Walker, 1983 .

In situ Probing of Adenine Protonation in RNA by 13C NMR

A. Pardi, P. Legault, 1994 .

Structural variation induced by different nucleotides at the cleavage site of the hammerhead ribozyme.

O. Uhlenbeck, A. Pardi, J. Simorre, 1998, Biochemistry.

A curved RNA helix incorporating an internal loop with G.A and A.A non-Watson-Crick base pairing.

S. Holbrook, A. Pardi, H. D. De Bondt, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Determination of DNA structures by NMR and distance geometry techniques: a computer simulation.

A. Pardi, D. Hare, C. Wang, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Calibration of the angular dependence of the amide proton-C alpha proton coupling constants, 3JHN alpha, in a globular protein. Use of 3JHN alpha for identification of helical secondary structure.

M. Billeter, K. Wüthrich, A. Pardi, 1984, Journal of molecular biology.

Chemically induced dynamic nuclear polarization studies of guanosine in nucleotides, dinucleotides, and oligonucleotides

I. Tinoco, A. Pardi, S. Boxer, 1984 .

Thermodynamics and kinetics for base-pair opening in the P1 duplex of the Tetrahymena group I ribozyme

A. Pardi, Joon-Hwa Lee, 2007, Nucleic acids research.

Isotope labelling for NMR studies of biomolecules

A. Pardi, Arthur Pardi, 1992 .

Optimized Reverse Micelle Surfactant System for High-Resolution NMR Spectroscopy of Encapsulated Proteins and Nucleic Acids Dissolved in Low Viscosity Fluids

A. Wand, A. Pardi, K. Valentine, 2014, Journal of the American Chemical Society.

A therapeutic aptamer inhibits angiogenesis by specifically targeting the heparin binding domain of VEGF165.

A. Pardi, F. Jucker, D. Shima, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Resolution-Enhanced Base-Type-Edited HCN Experiment for RNA

A. Pardi, J. Boisbouvier, J. Simorre, 2005, Journal of biomolecular NMR.

NMR solution structure of the lead-dependent ribozyme: evidence for dynamics in RNA catalysis.

A. Pardi, P. Legault, A Pardi, 1998, Journal of molecular biology.

Measurement of imino 1H–1H residual dipolar couplings in RNA

A. Pardi, M. Latham, 2009, Journal of biomolecular NMR.

Longitudinal-relaxation-enhanced NMR experiments for the study of nucleic acids in solution.

A. Pardi, J. Boisbouvier, P. Schanda, 2009, Journal of the American Chemical Society.

Improved Sensitivity and Resolution in 1 H- 13 C NMR Experiments of RNA

A. Pardi, J. Boisbouvier, J. Simorre, 1998 .

An efficient procedure for assignment of the proton, carbon and nitrogen resonances in 13C/15N labeled nucleic acids.

A. Pardi, E. Nikonowicz, 1993, Journal of molecular biology.

Multidimensional heteronuclear NMR experiments for structure determination of isotopically labeled RNA.

A. Pardi, 1995, Methods in enzymology.

Filamentous bacteriophage for aligning RNA, DNA, and proteins for measurement of nuclear magnetic resonance dipolar coupling interactions.

A. Pardi, M. Hansen, P. Hanson, 2000, Methods in enzymology.

Preparation of 13C and 15N labelled RNAs for heteronuclear multi-dimensional NMR studies.

A. Pardi, E. Nikonowicz, F. Jucker, 1992, Nucleic acids research.

Triple resonance HNCCCH experiments for correlating exchangeable and nonexchangeable cytidine and uridine base protons in RNA

L. Mueller, B. Farmer, A. Pardi, 1995, Journal of biomolecular NMR.

Three-dimensional heteronuclear NMR studies of RNA

A. Pardi, E. Nikonowicz, 1992, Nature.

Unambiguous through-bond sugar-to-base correlations for purines in 13C, 15N-labeled nucleic acids: The HsCsNb, HsCs(N)bCb, and HbNbCb experiments

B. Farmer, A. Pardi, E. Nikonowicz, 1994, Journal of biomolecular NMR.

Application of four-dimensional heteronuclear NMR to the structure determination of a uniformly 13C labeled RNA

A. Pardi, E. Nikonowicz, 1992 .

TRIPLE-RESONANCE EXPERIMENTS FOR ASSIGNMENT OF ADENINE BASE RESONANCES IN 13C/15N-LABELED RNA

L. Mueller, A. Pardi, G. Zimmermann, 1996 .

Sequence-dependent structural variations of hammerhead RNA enzymes.

O. Uhlenbeck, H. Heus, A. Pardi, 1990, Nucleic acids research.

Numbering system for the hammerhead.

R Cedergren, S Uesugi, O. Uhlenbeck, 1992, Nucleic acids research.

NMR Methods for Studying the Structure and Dynamics of RNA

A. Pardi, S. McCallum, Arthur Pardi, 2005, Chembiochem : a European journal of chemical biology.

High-performance liquid chromatography purification of homogenous-length RNA produced by trans cleavage with a hammerhead ribozyme.

A. Pardi, E. Mollova, M. Hansen, 1999, RNA.

Determining local conformational variations in DNA. Nuclear magnetic resonance structures of the DNA duplexes d(CGCCTAATCG) and d(CGTCACGCGC) generated using back-calculation of the nuclear Overhauser effect spectra, a distance geometry algorithm and constrained molecular dynamics.

R. Levy, A. Pardi, D. Kitchen, 1990, Journal of molecular biology.

High-resolution pyrimidine- and ribose-specific 4D HCCH-COSY spectra of RNA using the filter diagonalization method

A. Pardi, J. Douglas, G. Armstrong, 2008, Journal of biomolecular NMR.

Improved measurement of 13C, 31P J coupling constants in isotopically labeled RNA

A. Pardi, F. Jucker, P. Legault, 1995, FEBS letters.

Slow inhibition and conformation selective properties of extracellular signal-regulated kinase 1 and 2 inhibitors.

A. Pardi, N. Ahn, J. Rudolph, 2015, Biochemistry.

Dynamics of protein kinases: insights from nuclear magnetic resonance.

A. Pardi, N. Ahn, Yao Xiao, 2015, Accounts of chemical research.

Sequence-specific 1H NMR assignments, secondary structure, and location of the calcium binding site in the first epidermal growth factor like domain of blood coagulation factor IX.

A. Pardi, L. H. Huang, J. Tam, 1991, Biochemistry.

A semiconserved residue inhibits complex formation by stabilizing interactions in the free state of a theophylline-binding RNA.

A. Pardi, G. Zimmermann, R. Jenison, 1998, Biochemistry.

The cavity-chaperone Skp protects its substrate from aggregation but allows independent folding of substrate domains

A. Pardi, M. Sousa, T. A. Walton, 2009, Proceedings of the National Academy of Sciences.

A conformational change in the catalytic core of the hammerhead ribozyme upon cleavage of an RNA substrate.

A. Pardi, J. Simorre, P. Legault, 1997, Biochemistry.

Structural features that give rise to the unusual stability of RNA hairpins containing GNRA loops.

H. Heus, A. Pardi, A Pardi, 1991, Science.

Order, dynamics and metal-binding in the lead-dependent ribozyme.

A. Pardi, P. Legault, C. G. Hoogstraten, 1998, Journal of molecular biology.

Nuclear magnetic resonance studies of the hammerhead ribozyme domain. Secondary structure formation and magnesium ion dependence.

H. Heus, A. Pardi, 1991, Journal of molecular biology.

Solution structure of the calcium channel antagonist ω‐conotoxin GVIA

A. Pardi, W. Metzler, J. Skalicky, 1993 .

Analysis of side‐chain conformational distributions in neutrophil peptide‐5 nmr structures

R. Levy, A. Pardi, D. Kominos, 1990, Biopolymers.

Solution structures of proteins from NMR data and modeling: alternative folds for neutrophil peptide 5.

R. Levy, A. Pardi, D. Kitchen, 1989, Biochemistry.

Protein conformation and proton nuclear-magnetic-resonance chemical shifts.

K. Wüthrich, A. Pardi, G. Wagner, 1983, European journal of biochemistry.

Phosphorylation releases constraints to domain motion in ERK2

Natalie G Ahn, Thomas Lee, A. Pardi, 2014, Proceedings of the National Academy of Sciences.

Metal ion dependence, thermodynamics, and kinetics for intramolecular docking of a GAAA tetraloop and receptor connected by a flexible linker.

Julie L. Fiore, A. Pardi, D. Nesbitt, 2006, Biochemistry.

Docking kinetics and equilibrium of a GAAA tetraloop-receptor motif probed by single-molecule FRET.

Julie L. Fiore, A. Pardi, D. Nesbitt, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Refined solution structure of the iron-responsive element RNA using residual dipolar couplings.

A. Pardi, S. McCallum, Arthur Pardi, 2003, Journal of molecular biology.

Observation of Long-Range 1H−1H Distances in Solution by Dipolar Coupling Interactions

A. Pardi, M. Rance, M. Hansen, 1998 .

Solution structure of tRNAVal from refinement of homology model against residual dipolar coupling and SAXS data

Ad Bax, Alexander Grishaev, Jinfa Ying, 2008, Journal of biomolecular NMR.

Two-dimensional NMR studies of the antimicrobial peptide NP-5.

A. Pardi, M. Selsted, A. Bach, 1987, Biochemistry.

Efficient ligation of the Schistosoma hammerhead ribozyme.

A. Pardi, F. Jucker, M. Canny, 2007, Biochemistry.

Molecular interactions and metal binding in the theophylline-binding core of an RNA aptamer.

A. Pardi, G. Zimmermann, R. Jenison, 2000, RNA.

Identification and characterization of a novel high affinity metal-binding site in the hammerhead ribozyme.

A. Pardi, J. Simorre, L. Beigelman, 1999, RNA.

The global conformation of the hammerhead ribozyme determined using residual dipolar couplings.

A. Pardi, K. Bondensgaard, E. Mollova, 2002, Biochemistry.

Unusual dynamics and pKa shift at the active site of a lead dependent ribozyme

A. Pardi, P. Legault, 1997 .

Through-bond correlation of adenine protons in a 13C-labeled ribozyme

L. Mueller, B. Farmer, A. Pardi, 1994 .

Simple procedure for resonance assignment of the sugar protons in 13C-labeled RNAs

A. Pardi, E. Nikonowicz, 1992 .

Fast cleavage kinetics of a natural hammerhead ribozyme.

Anastasia Khvorova, S. Jayasena, A. Pardi, 2004, Journal of the American Chemical Society.

NMR solution structure determination of RNAs.

A. Pardi, E. Mollova, A Pardi, 2000, Current opinion in structural biology.

RNA Structure Comes of Age

O. Uhlenbeck, A. Pardi, J. Feigon, 1997, Cell.

Sequence Dependence of DNA Conformation, Dynamics and Interactions in Solution

D. Patel, A. Pardi, K. Itakura, 1984 .

Improved RNA Structure Determination by Detection of NOE Contacts to Exchange-Broadened Amino Protons

L. Mueller, A. Pardi, P. Legault, 1995 .

Solution structure of the CUUG hairpin loop: a novel RNA tetraloop motif.

A. Pardi, F. Jucker, 1995, Biochemistry.

Ultrafast dynamics show that the theophylline and 3-methylxanthine aptamers employ a conformational capture mechanism for binding their ligands.

Sang Won Lee, Liang Zhao, T. Xia, 2010, Biochemistry.

Role of a heterogeneous free state in the formation of a specific RNA-theophylline complex.

A. Pardi, F. Jucker, S. McCallum, 2003, Biochemistry.

Determining DNA Global Structure and DNA Bending by Application of NMR Residual Dipolar Couplings

Annaleen Vermeulen, A. Pardi, and Hongjun Zhou, 2000 .

NMR chemical exchange as a probe for ligand-binding kinetics in a theophylline-binding RNA aptamer.

A. Pardi, G. Zimmermann, M. Latham, 2009, Journal of the American Chemical Society.

NMR Determination of Sugar Puckers in Nucleic Acids from CSA−Dipolar Cross-Correlated Relaxation

A. Pardi, J. Boisbouvier, J. Simorre, 2000 .

GNRA tetraloops make a U-turn.

A. Pardi, F. Jucker, A Pardi, 1995, RNA.

Structure of the BamC two-domain protein obtained by Rosetta with a limited NMR data set.

Oliver F. Lange, David Baker, Oliver F Lange, 2011, Journal of molecular biology.

Active site dynamics in the lead-dependent ribozyme.

A. Pardi, J. R. Wank, C. G. Hoogstraten, 2000, Biochemistry.

Limited sampling of conformational space by the distance geometry algorithm: implications for structures generated from NMR data.

A. Pardi, W. Metzler, W J Metzler, 1989, Biochemistry.

Comparison of alignment tensors generated for native tRNAVal using magnetic fields and liquid crystalline media

A. Pardi, P. Hanson, M. Latham, 2008, Journal of biomolecular NMR.

Imino proton exchange rates imply an induced‐fit binding mechanism for the VEGF165‐targeting aptamer, Macugen

A. Pardi, F. Jucker, Joon-Hwa Lee, 2008, FEBS letters.

Refinement of local and long-range structural order in theophylline-binding RNA using (13)C-(1)H residual dipolar couplings and restrained molecular dynamics.

A. Pardi, M. Blackledge, J. Simorre, 2001, Journal of the American Chemical Society.

Global Structure of RNA Determined with Residual Dipolar Couplings

A. Pardi, E. Mollova, A. Hansen, 2000 .

Magnetic field induced residual dipolar couplings of imino groups in nucleic acids from measurements at a single magnetic field

A. Bax, A. Grishaev, Jinfa Ying, 2007, Journal of biomolecular NMR.

Structural effects on the circular dichroism of ethidium ion-nucleic acid complexes.

I. Tinoco, A. Pardi, K. Dahl, 1982, Biochemistry.

Incorporating residual dipolar couplings into the NMR solution structure determination of nucleic acids

A. Pardi, F. Jucker, A Pardi, 1999, Biopolymers.

Metal ion specificities for folding and cleavage activity in the Schistosoma hammerhead ribozyme.

A. Pardi, J. L. Boots, E. Azimi, 2008, RNA.

Imino proton exchange rates imply an induced‐fit binding mechanism for the VEGF165‐targeting aptamer, Macugen

A. Pardi, F. Jucker, Joon-Hwa Lee, 2008, FEBS letters.

Distinguishing between duplex and hairpin forms of RNA by 15N–1H heteronuclear NMR

A. Pardi, E. Nikonowicz, F. Aboul-ela, 1994, FEBS letters.

High-resolution pyrimidine- and ribose-specific 4D HCCH-COSY spectra of RNA using the filter diagonalization method

A. Pardi, J. Douglas, G. Armstrong, 2008, Journal of biomolecular NMR.

Measurement of carbon-phosphorus J coupling constants in RNA using spin-echo difference constant-time HCCH-COSY.

A. Pardi, C. G. Hoogstraten, 1998, Journal of magnetic resonance.

Chemical shift anisotropy of imino 15N nuclei in Watson-Crick base pairs from magic angle spinning liquid crystal NMR and nuclear spin relaxation.

A. Bax, A. Grishaev, L. Yao, 2009, Journal of the American Chemical Society.

1H-NMR Studies of the Structure and Calcium Binding Behavior of the First EGF-Like Domain in Blood Coagulation Factor IX,

A. Pardi, Hong Cheng, J. Tam, 1992 .