K. Ozaki

K. Ozaki, S. Niida, T. Sakurai, 2022, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

IMSindel: An accurate intermediate-size indel detection tool incorporating de novo assembly and gapped global-local alignment with split read analysis

Keith A. Boroevich, Shujiro Okuda, T. Tsunoda, 2018, Scientific Reports.

High-density single-nucleotide polymorphism (SNP) map in the 96-kb region containing the entire human DiGeorge syndrome critical region 2 (DGCR2) gene at 22q11.2

Yusuke Nakamura, Y. Ohnishi, Toshihiro Tanaka, 2001, Journal of Human Genetics.

Protective association of HLA‐DRB1*04 subtypes in neurodegenerative diseases implicates acetylated tau PHF6 sequences

Henrik, Michaël E. Belloy, Kaj, 2022, Alzheimer's & Dementia.

Identification of potential blood biomarkers for early diagnosis of Alzheimer’s disease through immune landscape analysis

K. Ozaki, S. Niida, D. Shigemizu, 2022, npj Aging.

Haplotypes with Copy Number and Single Nucleotide Polymorphisms in CYP2A6 Locus Are Associated with Smoking Quantity in a Japanese Population

Y. Okada, Yusuke Nakamura, Toshihiro Tanaka, 2012, PloS one.

Trans-ethnic Genomic Informed Risk Assessment for Alzheimer's disease: An International Hundred K+ Cohorts Consortium Study

John J. Connolly, Joseph T. Glessner, H. Hakonarson, 2022, medRxiv.

Early-onset Alzheimer Disease Associated With Neuromyelitis Optica Spectrum Disorder.

A. Nakamura, Takashi Kato, K. Ozaki, 2022, Alzheimer disease and associated disorders.

Expression and chromosomal localization of KIAA0369, a putative kinase structurally related to Doublecortin

Yusuke Nakamura, T. Fujiwara, K. Ozaki, 1998, Journal of Human Genetics.

Publisher Correction: IMSindel: An accurate intermediate-size indel detection tool incorporating de novo assembly and gapped global-local alignment with split read analysis

Tatsuhiko Tsunoda, Kouichi Ozaki, Shujiro Okuda, 2018, Scientific Reports.

Macular corneal dystrophy type I and type II are caused by distinct mutations in a new sulphotransferase gene

E. Thonar, A. Tanigami, T. Fujiwara, 2000, Nature Genetics.

Comparative analysis of cerebrospinal fluid metabolites in Alzheimer’s disease and idiopathic normal pressure hydrocephalus in a Japanese cohort

K. Ozaki, M. Kayano, S. Niida, 2018, Biomarker Research.

A functional polymorphism in THBS2 that affects alternative splicing and MMP binding is associated with lumbar-disc herniation.

Toshihiro Tanaka, K. Ozaki, T. Kubo, 2008, American journal of human genetics.

A comparison of machine learning classifiers for dementia with Lewy bodies using miRNA expression data

Tatsuhiko Tsunoda, Kouichi Ozaki, Daichi Shigemizu, 2019, BMC Medical Genomics.

JAMIR-eQTL: Japanese genome-wide identification of microRNA expression quantitative trait loci across dementia types

Kouichi Ozaki, Daichi Shigemizu, Shumpei Niida, 2021, Database J. Biol. Databases Curation.

Population-specific and trans-ancestry genome-wide analyses identify distinct and shared genetic risk loci for coronary artery disease

H. Aburatani, Y. Kamatani, K. Matsuda, 2020, Nature Genetics.

Complete cDNA sequence and genomic organization of a human pancreas-specific gene homologous to Caenorhabditis elegans sel-1

A. Tanigami, Yusuke Nakamura, T. Fujiwara, 1999, Journal of Human Genetics.

Integrating Genetic, Transcriptional, and Functional Analyses to Identify 5 Novel Genes for Atrial Fibrillation

K. Lunetta, A. Hofman, A. Uitterlinden, 2014, Circulation.

Meta-analysis identifies six new susceptibility loci for atrial fibrillation

K. Lunetta, A. Hofman, A. Uitterlinden, 2012, Nature Genetics.

Prognosis prediction model for conversion from mild cognitive impairment to Alzheimer’s disease created by integrative analysis of multi-omics data

Keith A. Boroevich, T. Tsunoda, K. Ozaki, 2020, Alzheimer's research & therapy.

Novel Calmodulin Mutations Associated With Congenital Arrhythmia Susceptibility

Takeshi Tsuchiya, Thomas Meitinger, Tatsuhiko Tsunoda, 2014, Circulation. Cardiovascular genetics.

Decreased mortality associated with statin treatment in patients with acute myocardial infarction and lymphotoxin-alpha C804A polymorphism.

Toshihiro Tanaka, K. Ozaki, I. Komuro, 2013, Atherosclerosis.

A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese.

Yusuke Nakamura, Y. Ohnishi, Toshihiro Tanaka, 2011, Human molecular genetics.

Lower DNA methylation levels in CpG island shores of CR1, CLU, and PICALM in the blood of Japanese Alzheimer’s disease patients

K. Ozaki, K. Sakaguchi, S. Niida, 2020, PloS one.

Isolation of a novel human lung‐specific gene, LUNX, a potential molecular marker for detection of micrometastasis in non‐small‐cell lung cancer

A. Tanigami, K. Ozaki, M. Monden, 2001, International journal of cancer.

A high-throughput SNP typing system for genome-wide association studies

Yusuke Nakamura, Kouichi Ozaki, Ryo Yamada, 2001, Journal of Human Genetics.

Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese.

K. Lunetta, J. Murabito, O. Franco, 2014, Journal of the American College of Cardiology.

Pathway analysis with genome-wide association study (GWAS) data detected the association of atrial fibrillation with the mTOR signaling pathway

Toshihiro Tanaka, K. Ozaki, T. Furukawa, 2019, International journal of cardiology. Heart & vasculature.

A functional polymorphism in COL11A1, which encodes the alpha 1 chain of type XI collagen, is associated with susceptibility to lumbar disc herniation.

Toshihiro Tanaka, K. Ozaki, T. Kubo, 2007, American journal of human genetics.

Ethnic and trans-ethnic genome-wide association studies identify new loci influencing Japanese Alzheimer’s disease risk

T. Morizono, K. Kinoshita, K. Ozaki, 2021, Translational Psychiatry.

Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases

M. Kanai, Y. Kamatani, Y. Okada, 2020, Nature Genetics.

A genome-wide association study identifies three new risk loci for Kawasaki disease

Yusuke Nakamura, Tatsuhiko Tsunoda, Kouichi Ozaki, 2012, Nature Genetics.

ITPKC and CASP3 polymorphisms and risks for IVIG unresponsiveness and coronary artery lesion formation in Kawasaki disease

T Tanaka, Toshihiro Tanaka, K. Ozaki, 2011, The Pharmacogenomics Journal.

Common variants in CASP3 confer susceptibility to Kawasaki disease.

Yusuke Nakamura, Tatsuhiko Tsunoda, Kouichi Ozaki, 2010, Human molecular genetics.

SNPs on chromosome 5p15.3 associated with myocardial infarction in Japanese population

Yusuke Nakamura, T. Kawaguchi, Toshihiro Tanaka, 2011, Journal of Human Genetics.

A functional SNP in FLT1 increases risk of coronary artery disease in a Japanese population

Tatsuhiko Tsunoda, Kouichi Ozaki, Michiaki Kubo, 2016, Journal of Human Genetics.

Identification of six new genetic loci associated with atrial fibrillation in the Japanese population

Y. Kamatani, P. Ellinor, Toshihiro Tanaka, 2017, Nature Genetics.

Common Variants in a Novel Gene, FONG on Chromosome 2q33.1 Confer Risk of Osteoporosis in Japanese

Yusuke Nakamura, Toshihiro Tanaka, S. Inoue, 2011, PloS one.

BRAP Activates Inflammatory Cascades and Increases the Risk for Carotid Atherosclerosis

Toshihiro Tanaka, K. Ozaki, S. Juo, 2011, Molecular medicine.

A functional SNP in ITIH3 is associated with susceptibility to myocardial infarction

Yusuke Nakamura, Toshihiro Tanaka, K. Ozaki, 2007, Journal of Human Genetics.

Genome-Wide Association Study of Peripheral Arterial Disease in a Japanese Population

T. Morizono, Toshihiro Tanaka, T. Tsunoda, 2015, PloS one.

A functional SNP in PSMA6 confers risk of myocardial infarction in the Japanese population

Yusuke Nakamura, Toshihiro Tanaka, T. Tsunoda, 2006, Nature Genetics.

Inflammation as a risk factor for myocardial infarction

Toshihiro Tanaka, K. Ozaki, 2006, Journal of Human Genetics.

Genome-wide association study to identify SNPs conferring risk of myocardial infarction and their functional analyses

K. Ozaki, K. Ozaki, T. Tanaka, 2005, Cellular and Molecular Life Sciences CMLS.

Exome Analyses of Long QT Syndrome Reveal Candidate Pathogenic Mutations in Calmodulin-Interacting Genes

Toshihiro Tanaka, T. Tsunoda, Yutaka Suzuki, 2015, PloS one.

Molecular genetics of coronary artery disease

Kouichi Ozaki, Toshihiro Tanaka, K. Ozaki, 2015, Journal of Human Genetics.

A functional SNP in EDG2 increases susceptibility to knee osteoarthritis in Japanese.

Yusuke Nakamura, Toshihiro Tanaka, T. Tsunoda, 2008, Human molecular genetics.

Comparative analysis of cerebrospinal fluid metabolites in Alzheimer’s disease and idiopathic normal pressure hydrocephalus in a Japanese cohort

K. Ozaki, M. Kayano, S. Niida, 2018, Biomarker Research.

Cross-ancestry genome-wide analysis of atrial fibrillation unveils disease biology and enables cardioembolic risk prediction

H. Aburatani, Y. Kamatani, K. Matsuda, 2023, Nature Genetics.

Dementia subtype prediction models constructed by penalized regression methods for multiclass classification using serum microRNA expression data

K. Ozaki, T. Ochiya, S. Niida, 2021, Scientific Reports.

A functional variant of SHARPIN confers increased risk of late-onset Alzheimer’s disease

K. Ozaki, S. Niida, A. Miyashita, 2021, Journal of Human Genetics.

Trans-ancestry genome-wide analysis of atrial fibrillation provides new insights into disease biology and enables polygenic prediction of cardioembolic risk

H. Aburatani, Y. Kamatani, K. Matsuda, 2021, medRxiv.

Population-specific and transethnic genome-wide analyses reveal distinct and shared genetic risks of coronary artery disease

H. Aburatani, Y. Kamatani, K. Matsuda, 2019, bioRxiv.

Renin-angiotensin-aldosterone system polymorphisms and 5-year mortality in survivors of acute myocardial infarction: a report from the Osaka Acute Coronary Insufficiency Study.

Toshihiro Tanaka, K. Ozaki, I. Komuro, 2014, International heart journal.

Association of NOD2 Mutations with Aggressive Periodontitis

Y. Izumi, K. Ozaki, K. Urayama, 2017, Journal of dental research.

Reduced risk of recurrent myocardial infarction in homozygous carriers of the chromosome 9p21 rs1333049 C risk allele in the contemporary percutaneous coronary intervention era: a prospective observational study

Toshihiro Tanaka, K. Ozaki, I. Komuro, 2014, BMJ Open.

Isolation and characterization of a novel human pancreas‐specific gene, pancpin, that is down‐regulated in pancreatic cancer cells

Y. Nakamura, T. Fujiwara, K. Ozaki, 1998, Genes, chromosomes & cancer.

Genetics of Coronary Disease

Toshihiro Tanaka, K. Ozaki, 2019, Genome-Wide Association Studies.

Transethnic meta-analysis of genome-wide association studies identifies three new loci and characterizes population-specific differences for coronary artery disease

Y. Kamatani, K. Matsuda, K. Ozaki, 2019, bioRxiv.

Genetic Background of Myocardial Infarction

Toshihiro Tanaka, K. Ozaki, 2011 .

Genetic backgrounds of myocardial infarction

Toshihiro Tanaka, K. Ozaki, 2007 .

Genome-wide association study to identify single-nucleotide polymorphisms conferring risk of myocardial infarction.

Toshihiro Tanaka, K. Ozaki, 2006, Methods in molecular medicine.

Identification of potential blood biomarkers for early diagnosis of Alzheimer’s disease through RNA sequencing analysis

K. Ozaki, S. Niida, T. Sakurai, 2020, Alzheimer's Research & Therapy.

A rare functional variant of SHARPIN attenuates the inflammatory response and associates with increased risk of late-onset Alzheimer’s disease

K. Ozaki, S. Niida, A. Miyashita, 2019, Molecular Medicine.

Prediction model for knee osteoarthritis based on genetic and clinical information

Toshihiro Tanaka, K. Ozaki, N. Kamatani, 2010, Arthritis Research & Therapy.

Deep learning-based age estimation from chest X-rays indicates cardiovascular prognosis

K. Ozaki, Rei Kawakami, K. Fujiu, 2022, Communications medicine.

Deep learning-based chest X-ray age serves as a novel biomarker for cardiovascular aging

K. Ozaki, Rei Kawakami, I. Komuro, 2021, bioRxiv.

SNPs in BRAP associated with risk of myocardial infarction in Asian populations

Yusuke Nakamura, Toshihiro Tanaka, T. Tsunoda, 2009, Nature Genetics.

Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data

Keith A. Boroevich, T. Tsunoda, K. Ozaki, 2019, Communications Biology.

Association of the Tag SNPs in the Human SKT Gene (KIAA1217) With Lumbar Disc Herniation

K. Ozaki, T. Kubo, A. Takahashi, 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Impact of atherosclerosis-related gene polymorphisms on mortality and recurrent events after myocardial infarction.

Y. Ohnishi, Toshihiro Tanaka, K. Ozaki, 2006, Atherosclerosis.

Clinical utility and functional analysis of variants in atrial fibrillation-associated locus 4q25.

Toshihiro Tanaka, K. Ozaki, M. Kubo, 2017, Journal of cardiology.

Exploring the genetic diversity of the Japanese population: Insights from a large-scale whole genome sequencing analysis

K. Ozaki, S. Niida, K. Miyo, 2023, bioRxiv.

A rare functional variant of SHARPIN attenuates the inflammatory response and associates with increased risk of late-onset Alzheimer’s disease

K. Ozaki, S. Niida, A. Miyashita, 2019, Molecular medicine.

Classification and deep-learning–based prediction of Alzheimer disease subtypes by using genomic data

K. Ozaki, Yukiko Nakano, S. Niida, 2023, Translational psychiatry.

Fine-scale SNP map of an 11-kb genomic region at 22q13.1 containing the galectin-1 gene

Yusuke Nakamura, Toshihiro Tanaka, K. Ozaki, 2005, Journal of Human Genetics.