E. Leproust

发表

The DNA-encoded nucleosome organization of a eukaryotic genome

Irene K. Moore, T. Hughes, E. Segal, 2009, Nature.

The pluripotent regulatory circuitry connecting promoters to their long-range interacting elements

Cameron S. Osborne, Jennifer A. Mitchell, N. Luscombe, 2015, Genome research.

Exonic Transcription Factor Binding Directs Codon Choice and Affects Protein Evolution

Alex P. Reynolds, J. Stamatoyannopoulos, E. Haugen, 2013, Science.

Corrigendum: Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells

Madeleine P. Ball, Jehyuk Lee, M. Ball, 2009, Nature Biotechnology.

Multiplex padlock targeted sequencing reveals human hypermutable CpG variations.

A. Zaranek, G. Church, S. Sunyaev, 2009, Genome research.

Digital RNA Allelotyping Reveals Tissue-specific and Allele-specific Gene Expression in Human

Jehyuk Lee, G. Church, K. Eggan, 2009, Nature Methods.

Genome-Wide Identification of Human RNA Editing Sites by Parallel DNA Capturing and Sequencing

G. Church, E. Leproust, J. Aach, 2009, Science.

Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming

G. Daley, K. Hochedlinger, K. Eggan, 2009, Nature Biotechnology.

Evidence for the biogenesis of more than 1,000 novel human microRNAs

Xavier Estivill, Justo González, Marc R Friedländer, 2014, Genome Biology.

Targeted and genome-scale methylomics reveals gene body signatures in human cell lines

Madeleine P. Ball, Jehyuk Lee, M. Ball, 2009, Nature Biotechnology.

Enrichment of sequencing targets from the human genome by solution hybridization

K. Frazer, O. Harismendy, Xiaoyun Wang, 2009, Genome Biology.

Specific Capture and Whole-Genome Sequencing of Viruses from Clinical Samples

E. Leproust, P. Kellam, A. Palser, 2011, PloS one.

Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C

Philip A. Ewels, Cameron S. Osborne, N. Luscombe, 2015, Nature Genetics.

A Systematic Mammalian Genetic Interaction Map Reveals Pathways Underlying Ricin Susceptibility

Michael T. McManus, Max A. Horlbeck, Marco Y. Hein, 2013, Cell.

The GENCODE exome: sequencing the complete human exome

J. Harrow, F. Kokocinski, T. Hubbard, 2011, European Journal of Human Genetics.

Scalable gene synthesis by selective amplification of DNA pools from high-fidelity microchips

Sriram Kosuri, George M Church, Emily M LeProust, 2010, Nature Biotechnology.

Synthesis of high-quality libraries of long (150mer) oligonucleotides by a novel depurination controlled process

Emily M. LeProust, Eugeni Namsaraev, M. Caruthers, 2010, Nucleic acids research.

List of Publications Faculty Opponent

E. Leproust, A. Syvänen, Ii., 2022 .

A flexible light-directed DNA chip synthesis gated by deprotection using solution photogenerated acids.

E. Leproust, E. Gulari, E. Leproust, 2001, Nucleic acids research.

Application of a synthetic human proteome to autoantigen discovery through PhIP-Seq

G. Church, S. Elledge, E. Leproust, 2011, Nature Biotechnology.

Autoantigen discovery with a synthetic human peptidome.

Uri Laserson, George M Church, Santosh Kesari, 2011, Nature biotechnology.

Solution Hybrid Selection with Ultra-long Oligonucleotides for Massively Parallel Targeted Sequencing

J. Maguire, T. Fennell, S. Gabriel, 2009, Nature Biotechnology.

Targeted genome enrichment for efficient purification of endosymbiont DNA from host DNA

B. Moumen, C. Hendrickson, E. Leproust, 2012, Symbiosis.

An efficient and economic site-specific deuteration strategy for NMR studies of homologous oligonucleotide repeat sequences.

E. Leproust, Xiaolian Gao, E. Leproust, 1997, Nucleic acids research.

Mitochondrial disease genetic diagnostics: optimized whole-exome analysis for all MitoCarta nuclear genes and the mitochondrial genome.

Xiaowu Gai, Marni J. Falk, E. Leproust, 2012, Discovery medicine.

Myofibrillar myopathy caused by a mutation in the motor domain of mouse MyHC IIb.

E. Leproust, G. Blanco, P. Denny, 2012, Human molecular genetics.

hypermutable CpG variations Multiplex padlock targeted sequencing reveals human Material

A. Zaranek, G. Church, S. Sunyaev, 2009 .

Towards practical, high-capacity, low-maintenance information storage in synthesized DNA

Ewan Birney, Christophe Dessimoz, Siyuan Chen, 2013, Nature.

Multiplex amplification of large sets of human exons

Jay Shendure, Bin Xie, George M Church, 2007, Nature Methods.

Systematic Identification of Barriers to Human iPSC Generation

Michael T. McManus, Jun S. Song, Miguel Ramalho-Santos, 2014, Cell.

Advancing genetic testing for deafness with genomic technology

Adam P. DeLuca, Christina M. Sloan, T. Casavant, 2013, Journal of Medical Genetics.

Polycomb repressive complex PRC1 spatially constrains the mouse embryonic stem cell genome

Louise S. Matheson, Cameron S. Osborne, N. Luscombe, 2015, Nature Genetics.

Rapid Creation and Quantitative Monitoring of High Coverage shRNA Libraries

Michael T. McManus, Nicholas T. Ingolia, J. Weissman, 2009, Nature Methods.

Temporal and Spatial Profile of Brain Diffusion-Weighted MRI After Cardiac Arrest

Roland Bammer, Nancy J Fischbein, Michael Mlynash, 2010, Stroke.

Utilizing ethnic-specific differences in minor allele frequency to recategorize reported pathogenic deafness variants.

Thomas L Casavant, Todd E Scheetz, E Ann Black-Ziegelbein, 2014, American journal of human genetics.

Pre-capture multiplexing improves efficiency and cost-effectiveness of targeted genomic enrichment

E. Leproust, Richard Smith, B. Novak, 2012, BMC Genomics.

Efficient and Cost Effective Population Resequencing by Pooling and In-Solution Hybridization

Vikas Bansal, Nicholas J. Schork, Emily M. LeProust, 2011, PloS one.

Safety by design: Biosafety and biosecurity in the age of synthetic genomics

D. Densmore, J. Boeke, E. Leproust, 2023, iScience.

Next Steps for Access to Safe, Secure DNA Synthesis

James Diggans, Emily Leproust, E. Leproust, 2019, Front. Bioeng. Biotechnol..

Digital light-directed synthesis. A microarray platform that permits rapid reaction optimization on a combinatorial basis.

E. Leproust, E. Gulari, E. Leproust, 2000, Journal of combinatorial chemistry.

Characterization of oligodeoxyribonucleotide synthesis on glass plates.

E. Leproust, E. Leproust, Xiaochuan Zhou, 2001, Nucleic acids research.

Target enrichment strategies for next generation sequencing.

E. Leproust, 2012, MLO: medical laboratory observer.

A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation

Michael T. McManus, J. Weissman, E. Leproust, 2014, Nature Communications.

Structure-guided SCHEMA recombination generates diverse chimeric channelrhodopsins

Frances H. Arnold, Xiaozhe Ding, Viviana Gradinaru, 2017, Proceedings of the National Academy of Sciences.

Toward practical high-capacity low-maintenance storage of digital information in synthesised DNA

Ewan Birney, Christophe Dessimoz, Botond Sipos, 2013 .

A Scalable Gene Synthesis Platform Using High-Fidelity DNA Microchips

G. Church, S. Kosuri, E. Leproust, 2010, Nature biotechnology.