J. Seibyl

J. Seibyl, M. Laruelle, S. Zoghbi, 2002, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Striatal dopamine transporter availability with [123I]β-CIT SPECT is unrelated to gender or menstrual cycle

J. Seibyl, M. Laruelle, S. Zoghbi, 2005, Psychopharmacology.

CSF biomarkers of Alzheimer’s disease concord with amyloid-β PETand predict clinical progression: A study of fully automated immunoassays in BioFINDER and ADNI cohorts

J. Trojanowski, K. Blennow, L. Shaw, 2018, Alzheimer's & Dementia.

The role of the core imaging laboratory in multicenter trials.

J. Seibyl, I. Zubal, K. Marek, 2010, Seminars in nuclear medicine.

The Qualification of an Enrichment Biomarker for Clinical Trials Targeting Early Stages of Parkinson’s Disease

D. Hill, T. Nicholas, D. Jennings, 2019, Journal of Parkinson's disease.

Molecular PET imaging in multicenter Alzheimer’s therapeutic trials: current trends and implementation strategies

P. Doraiswamy, D. Jennings, J. Seibyl, 2011, Expert review of neurotherapeutics.

The role of neuroimaging in the early diagnosis and evaluation of Parkinson's disease.

J. Seibyl, K. Marek, D. Jennings, 2005, Minerva medica.

The role of radiotracer imaging in Parkinson disease

K. Gwinn‐Hardy, R. Albin, W. Oertel, 2005, Neurology.

Optimized, Automated Striatal Uptake Analysis Applied to SPECT Brain Scans of Parkinson's Disease Patients

D. Jennings, J. Seibyl, I. Zubal, 2007, Journal of Nuclear Medicine.

Biomarkers for Parkison's disease: Tools to assess Parkinson's disease onset and progression

D. Jennings, J. Seibyl, K. Marek, 2008, Annals of neurology.

Estimating the half-lives of PCB congeners in former capacitor workers measured over a 28-year interval

D. Jennings, J. Seibyl, S. Factor, 2011, Journal of Exposure Science and Environmental Epidemiology.

Cerebral amyloid-β PET with florbetaben (18F) in patients with Alzheimer's disease and healthy controls: a multicentre phase 2 diagnostic study

John Seibyl, Katharina Buerger, Osama Sabri, 2011, The Lancet Neurology.

Imaging prodromal Parkinson disease

D. Jennings, J. Seibyl, A. Siderowf, 2014, Neurology.

Florbetaben PET imaging to detect amyloid beta plaques in Alzheimer's disease: Phase 3 study

John Seibyl, Yasuomi Ouchi, Ana M. Catafau, 2015, Alzheimer's & Dementia.

Individual-Reader Diagnostic Performance and Between-Reader Agreement in Assessment of Subjects with Parkinsonian Syndrome or Dementia Using 123I-Ioflupane Injection (DaTscan) Imaging

Jacques Darcourt, Jan Booij, Andreas Kupsch, 2014, The Journal of Nuclear Medicine.

Graphical, Kinetic, and Equilibrium Analyses of in vivo [123I]β-CIT Binding to Dopamine Transporters in Healthy Human Subjects

Robert B. Innis, Marc Laruelle, Dennis S. Charney, 1994, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Pramipexole vs levodopa as initial treatment for Parkinson disease: a 4-year randomized controlled trial.

John Seibyl, Mark Stacy, Stanley Fahn, 2004, Archives of neurology.

Decreased single‐photon emission computed tomographic {123I}β‐CIT striatal uptake correlates with symptom severity in parkinson's disease

Eileen O. Smith, J. Seibyl, D. Charney, 1995, Annals of neurology.

Pramipexole vs levodopa as initial treatment for Parkinson disease: A randomized controlled trial. Parkinson Study Group.

John Seibyl, Anthony E. Lang, Stanley Fahn, 2000, JAMA.

Decreased cerebral blood flow during seizures with ictal SPECT injections

Colin Studholme, Rik Stokking, John P Seibyl, 2000, Epilepsy Research.

Correction for crosstalk contaminations in dual radionuclide /sup 99m/Tc and /sup 123/I images using artificial neural network

M. King, J. Seibyl, I. Zubal, 2004, IEEE Transactions on Nuclear Science.

123I beta-CIT Assessment of progression in Parkinsons disease

Eileen O. Smith, J. Seibyl, K. Marek, 1997 .

In vivo evaluation of [¹²³I]mZIENT as a SPECT radioligand for the serotonin transporter.

J. Seibyl, K. Cosgrove, M. Goodman, 2012, Nuclear medicine and biology.

EANM practice guideline/SNMMI procedure standard for dopaminergic imaging in Parkinsonian syndromes 1.0

R. Boellaard, S. Pappatà, N. Bohnen, 2020, European Journal of Nuclear Medicine and Molecular Imaging.

No Evidence of Altered In Vivo Benzodiazepine Receptor Binding in Schizophrenia

John Seibyl, Osama Mawlawi, Marc Laruelle, 1999, Neuropsychopharmacology.

Effects of Vigabatrin on the GABAergic System as Determined by [123I]Iomazenil SPECT and GABA MRS

R. Mattson, F. Hyder, J. Seibyl, 1999, Epilepsia.

Amphetamine‐stimulated dopamine release competes in vivo for [123I]IBZM binding to the D2 receptor in nonhuman primates

Marc Laruelle, Eileen O. Smith, R. Roth, 1992, Synapse.

Pharmacokinetics of the three radioiodinated dopamine D2 receptor ligands [123I]IBF, [123I]epidepride and [123I]2'-ISP in nonhuman primates.

E. Sybirska, J. Seibyl, D. Charney, 1994, Nuclear medicine and biology.

The role of positron emission tomography imaging in understanding Alzheimer’s disease

J. Seibyl, O. Sabri, H. Barthel, 2015, Expert review of neurotherapeutics.

Feasibility and Safety of Multicenter Tissue and Biofluid Sampling for α-Synuclein in Parkinson’s Disease: The Systemic Synuclein Sampling Study (S4)

C. Adler, D. Jennings, J. Seibyl, 2018, Journal of Parkinson's disease.

Iodine‐123 labeled reboxetine analogues for imaging of noradrenaline transporter in brain using single photon emission computed tomography

J. Seibyl, S. Pimlott, G. Tamagnan, 2012, Synapse.

beta2 Nicotinic acetylcholine receptor availability in post-traumatic stress disorder.

J. Krystal, J. Seibyl, J. Staley, 2008, The international journal of neuropsychopharmacology.

b 2 Nicotinic acetylcholine receptor availability in post-traumatic stress disorder

J. Krystal, J. Seibyl, J. Staley, 2008 .

Imaging Studies with A2A Receptor Antagonists

J. Seibyl, G. Tamagnan, O. Barret, 2015 .

Serum urate and probability of dopaminergic deficit in early “Parkinson's disease”

D. Jennings, J. Seibyl, I. Shoulson, 2011, Movement disorders : official journal of the Movement Disorder Society.

Affective Reactivity of Language in Schizophrenia

J. Krystal, J. Seibyl, I. M. Evans, 1994, The Journal of nervous and mental disease.

[123I]β‐CIT SPECT imaging demonstrates reduced density of striatal dopamine transporters in Parkinson's disease and multiple system atrophy

Robert B. Innis, John Seibyl, Andrea Varrone, 2001 .

Impact of disclosure of individual imaging results in a multi-center Parkinson clinical trial.

D. Jennings, J. Seibyl, I. Shoulson, 2014, Journal of Parkinson's disease.

SPECT and PET in Atypical Parkinsonism.

J. Seibyl, 2010, PET clinics.

Perspectives on the role of serotonergic mechanisms in the pharmacology of schizophrenia

J. Seibyl, 1997, Journal of psychopharmacology.

Kinetic Analysis of the Metabotropic Glutamate Subtype 5 Tracer [18F]FPEB in Bolus and Bolus-Plus-Constant-Infusion Studies in Humans

Jenna M. Sullivan, Yiyun Huang, J. Seibyl, 2013, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

PRECLINICAL AND CLINICAL PROPERTIES OF [123I]ABC577: A NOVEL RADIOIODINATED SPECT AGENT FOR IMAGING B-AMYLOID IN THE BRAIN

D. Jennings, J. Seibyl, K. Marek, 2014, Alzheimer's & Dementia.

Pharmacokinetic Modeling and [123I]5-IA-85380 Single Photon Emission Computed Tomography Imaging in Baboons: Optimization of Dosing Regimen for ABT-089

D. Llano, M. Day, J. Seibyl, 2011, Journal of Pharmacology and Experimental Therapeutics.

Safety Analysis of 10 Clinical Trials and for 13 Years After First Approval of Ioflupane 123I Injection (DaTscan)

E. Tolosa, A. Kupsch, W. Oertel, 2014, The Journal of Nuclear Medicine.

FMR1 gene expansion and scans without evidence of dopaminergic deficits in parkinsonism patients.

J. Seibyl, K. Marek, D. Hall, 2010, Parkinsonism & related disorders.

Lower ß2*-nicotinic acetylcholine receptor availability in smokers with schizophrenia.

John Seibyl, Kelly P. Cosgrove, Brian Pittman, 2012, The American journal of psychiatry.

Measurement of plasma metabolites of (S)-5-[123I]iodo-3-(2-azetidinylmethoxy)pyridine (5-IA-85380), a nicotinic acetylcholine receptor imaging agent, in nonhuman primates.

J. Seibyl, S. Zoghbi, R. Innis, 2001, Nuclear medicine and biology.

Clinical correlates of raphe serotonergic dysfunction in early Parkinson's disease.

J. Seibyl, D. Brooks, K. Marek, 2015, Brain : a journal of neurology.

Seed Amplification Assay to Diagnose Early Parkinson's and Predict Dopaminergic Deficit Progression

J. Seibyl, C. Soto, K. Merchant, 2021, Movement disorders : official journal of the Movement Disorder Society.

Synthesis and biological evaluation of positron emission tomography radiotracers targeting serotonin 4 receptors in brain: [18F]MNI-698 and [18F]MNI-699.

J. Seibyl, R. Baldwin, G. Tamagnan, 2013, Bioorganic & medicinal chemistry letters.

Occupational exposure to PCBs reduces striatal dopamine transporter densities only in women: A β-CIT imaging study

D. Jennings, J. Seibyl, S. Factor, 2010, Neurobiology of Disease.

Intrastriatal alpha-synuclein fibrils in monkeys: spreading, imaging and neuropathological changes.

J. Trojanowski, J. Seibyl, K. Marek, 2019, Brain : a journal of neurology.

Positron emission tomography for the evaluation of patients with colorectal cancer.

J. Seibyl, S. Kummar, J. Arrighi, 2001, Clinical colorectal cancer.

[18F]GTP1 (Genentech Tau Probe 1), a radioligand for detecting neurofibrillary tangle tau pathology in Alzheimer’s disease

G. Kerchner, J. Seibyl, K. Marek, 2019, European Journal of Nuclear Medicine and Molecular Imaging.

Reduced Expression of Cerebral Metabotropic Glutamate Receptor Subtype 5 in Men with Fragile X Syndrome

James Robert Brašić, Zabecca S. Brinson, Samuel D. Martin, 2020, Brain sciences.

Chest radiograph as a triage tool in the imaging-based diagnosis of pulmonary embolism.

J. Seibyl, A. Daftary, M. Gregory, 2005, AJR. American journal of roentgenology.

Reproducibility of serial peri-ictal single-photon emission tomography difference images in epilepsy patients undergoing surgical resection

Gina N Morano, C. Studholme, D. Spencer, 2000, European Journal of Nuclear Medicine.

Medical imaging in neurological disorders.

J. Seibyl, H. Chugani, A. Waxman, 2002, Journal of the American Pharmaceutical Association.

Ratio‐Images Calculated From Interictal Positron Emission Tomography and Single‐Photon Emission Computed Tomography for Quantification of the Uncoupling of Brain Metabolism and Perfusion in Epilepsy

C. Studholme, J. Seibyl, S. Spencer, 2000 .

Use of white matter reference regions for detection of change in florbetapir positron emission tomography from completed phase 3 solanezumab trials

M. Mintun, A. Fleisher, E. Siemers, 2017, Alzheimer's & Dementia.

Clinical significance of neurological soft signs in schizophrenia: Factor analysis of the Neurological Evaluation Scale

J. Krystal, J. Seibyl, D. D’Souza, 2010, Schizophrenia Research.

123I‐FP‐CIT SPECT [(123) I‐2β‐carbomethoxy‐3β‐(4‐iodophenyl)‐N‐(3‐fluoropropyl) nortropane single photon emission computed tomography] Imaging in a p.A53T α‐synuclein Parkinson's disease cohort versus Parkinson's disease

J. Seibyl, M. Stamelou, K. Marek, 2018, Movement disorders : official journal of the Movement Disorder Society.

Iodine-123-beta-CIT and iodine-123-FPCIT SPECT measurement of dopamine transporters in healthy subjects and Parkinson's patients.

J. Seibyl, D. Charney, K. Marek, 1998, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Parkinson's Progression Markers Initiative brain autopsy program.

P. Muglia, J. Jankovic, M. Mintun, 2022, Parkinsonism & related disorders.

Feasibility of short imaging protocols for [18F]PI-2620 tau-PET in progressive supranuclear palsy

F. Jessen, J. Seibyl, A. Drzezga, 2021, European Journal of Nuclear Medicine and Molecular Imaging.

The Parkinson's progression markers initiative (PPMI) – establishing a PD biomarker cohort

Norbert Schuff, Arthur W. Toga, John Seibyl, 2018, Annals of clinical and translational neurology.

Cerebellar amyloid-beta plaques: How frequent are they, and do they influence 18 F-Florbetaben SUVR?

J. Seibyl, B. Ghetti, O. Sabri, 2016 .

Single-photon emission tomography and dopamine transporter imaging in Parkinson's disease.

D. Jennings, J. Seibyl, K. Marek, 2003, Advances in neurology.

Molecular Imaging Insights into Neurodegeneration: Focus on α-Synuclein Radiotracers

J. Seibyl, A. Catafau, A. Cartier, 2014, The Journal of Nuclear Medicine.

Molecular Neuroimaging of the Dopamine Transporter as a Patient Enrichment Biomarker for Clinical Trials for Early Parkinson's Disease

D. Hill, T. Nicholas, J. Seibyl, 2019, Clinical and translational science.

Brain distribution of BZM055, an analog of fingolimod (FTY720), in human

D. Jennings, J. Seibyl, K. Marek, 2012 .

Yes we can analyse amyloid images - Now What?

J. Seibyl, O. Sabri, H. Barthel, 2017, European Journal of Nuclear Medicine and Molecular Imaging.

123-I Ioflupane SPECT measures of Parkinson disease progression in the Parkinson Progression Marker Initiative (PPMI) trial

John Seibyl, Igor D. Grachev, Christopher S. Coffey, 2013 .

Elevated CSF levels of interleukin-2 in neuroleptic-free schizophrenic patients.

J. Krystal, J. Licinio, J. Seibyl, 1993, The American journal of psychiatry.

Award Number: W81XWH-09-1-0134 TITLE: Imaging Neuroinflammation in Post Traumatic Stress Disorder

J. Seibyl, 2012 .

Measurement of a432 Nicotinic Acetyicholine Receptors with [ @ 23J]5.I.A. 85 380 SPECT

Fujita, J. Seibyl, S. Zoghbi, 2006 .

Edinburgh Research Explorer Cerebellar amyloid-beta plaques: How frequent are they, and do they influence 18F-Florbetaben SUVR?

J. Seibyl, B. Ghetti, O. Sabri, 2016 .

Measurement of Amyloid-b Peptides in Cerebrospinal Fluid and Plasma Specimens from Patients with Alzheimer’s Disease Treated with Solanezu-

Nick C Fox, E. Liu, J. Seibyl, 2013 .

Within assay Between assay Within assay Between assay

E. Liu, J. Seibyl, B. Wyman, 2013 .

6‐[123I]Iodo‐2‐[[4‐(2‐methoxyphenyl) piperazin‐1‐yl]methyl]imidazo[1,2‐a]pyridine as potential SPECT agent for imaging dopamine D4 receptor: synthesis and in vivo evaluation in a nonhuman primate

J. Seibyl, K. Cosgrove, J. Staley, 2008 .

Radiation Dosimetry of 18F-FPEB in Humans

J. Seibyl, D. Zald, R. Kessler, 2014, The Journal of Nuclear Medicine.

Effects of ritanserin on the behavioral, neuroendocrine, and cardiovascular responses to meta-chlorophenylpiperazine in healthy human subjects

S. Woods, J. Krystal, J. Seibyl, 1991, Psychiatry Research.

Brain intrinsic network connectivity in individuals with frequent tanning behavior

J. Seibyl, F. Filbey, B. Adinoff, 2018, The American journal of drug and alcohol abuse.

[123I]β-CIT SPECT imaging of dopamine transporter availability after mazindol administration in human cocaine addicts

J. Seibyl, L. Price, L. Carpenter, 1998, Psychopharmacology.

Cerebral perfusion changes in older delirious patients using 99mTc HMPAO SPECT.

J. Seibyl, H. Blumenfeld, S. Inouye, 2006, The journals of gerontology. Series A, Biological sciences and medical sciences.

Reduced brain serotonin transporter availability in major depression as measured by [123I]-2β-carbomethoxy-3β-(4-iodophenyl)tropane and single photon emission computed tomography

Linda Carpenter, John P Seibyl, Robert B Innis, 1998, Biological Psychiatry.

Rapid Communication Age-related decline in central serotonin transporter availability with ( 123 I)b-CIT SPECT <

J. Seibyl, M. Laruelle, S. Zoghbi, 2000 .

Reproducibility of iodine-123-beta-CIT SPECT brain measurement of dopamine transporters.

J. Seibyl, D. Charney, M. Laruelle, 1996, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Effect of scatter correction on the compartmental measurement of striatal and extrastriatal dopamine D 2 receptors using

J. Seibyl, H. Watabe, H. Iida, 2004 .

Histopathology and Florbetaben PET in Patients Incorrectly Diagnosed with Alzheimer's Disease.

C. Rowe, M. Sabbagh, J. Seibyl, 2017, Journal of Alzheimer's disease : JAD.

Optimized classification of 18F-Florbetaben PET scans as positive and negative using an SUVR quantitative approach and comparison to visual assessment

John Seibyl, Ana M. Catafau, Osama Sabri, 2017, NeuroImage: Clinical.

18F-Florbetaben (FBB) PET SUVR quantification: Which reference region?

C. Rowe, J. Seibyl, V. Villemagne, 2015 .

Dopamine Transporter Imaging Assessment of Parkinson's Disease Progression

J. Seibyl, K. Marek, 2000 .

Longitudinal clinical and biomarker characteristics of non-manifesting LRRK2 G2019S carriers in the PPMI cohort

Yen F. Tai, P. Muglia, J. Jankovic, 2022, npj Parkinson's Disease.

Effect of a nicotine vaccine on nicotine binding to the beta2-nAChRs in vivo in human tobacco smokers

J. Seibyl, K. Cosgrove, R. Tyndale, 2013 .

Central type benzodiazepine receptors in Gulf War veterans with posttraumatic stress disorder

S. Southwick, J. Seibyl, S. Zoghbi, 2004, Biological Psychiatry.

Diffusion tensor imaging of the nigrostriatal fibers in Parkinson's disease

Norbert Schuff, John Seibyl, Christopher S Coffey, 2015, Movement disorders : official journal of the Movement Disorder Society.

Comparison of 3 F-18 TSPO ligands in non-human primates

J. Seibyl, R. Carson, D. Weinzimmer, 2010 .

A NEGATIVE FLORBETABEN PET SCAN RELIABLY EXCLUDES AMYLOID PATHOLOGY AS CONFIRMED BY HISTOPATHOLOGY

C. Rowe, J. Seibyl, W. Schulz-Schaeffer, 2014, Alzheimer's & Dementia.

Changes in Human In vivo Serotonin and Dopamine Transporter Availabilities during Chronic Antidepressant Administration

Stephen A. Williams, P. Snyder, J. Seibyl, 2003, Neuropsychopharmacology.

Feasibility and safety of lumbar puncture in the Parkinson's disease research participants: Parkinson's Progression Marker Initiative (PPMI).

Yen F. Tai, P. Muglia, J. Jankovic, 2019, Parkinsonism & related disorders.

Serotonin Function in Tardive Dyskinesia

J. Seibyl, R. Innis, W. Glazer, 1989 .

Imaging extrastriatal dopamine D(2) receptor occupancy by endogenous dopamine in healthy humans.

M Fujita, J. Seibyl, R. Innis, 2000, European journal of pharmacology.

Synthesis and receptor binding studies of halogenated N,N-dialkylel-(2-phenyl-1H-indol-3-yl)glyoxylamides to visualize peripheral benzodiazepine receptors with SPECT or PET.

J. Seibyl, J. Staley, R. Baldwin, 2006, Bioorganic & medicinal chemistry.

Central serotonin transporter availability measured with [123I]beta-CIT SPECT in relation to serotonin transporter genotype.

Marc Laruelle, Joel Gelernter, John P Seibyl, 2004, The American journal of psychiatry.

Sex differences in [123I]β‐CIT SPECT measures of dopamine and serotonin transporter availability in healthy smokers and nonsmokers

M Fujita, J. Seibyl, J. Staley, 2001, Synapse.

Prediction of dopamine transporter binding availability by genotype: a preliminary report.

J. Seibyl, J. Staley, L. Jacobsen, 2000, The American journal of psychiatry.

Changes of benzodiazepine receptors during chronic benzodiazepine administration in humans.

S. Woods, J. Krystal, J. Seibyl, 1999, European journal of pharmacology.

Improved Risk Stratification for Progression from Mild Cognitive Impairment to Alzheimer's Disease with a Multi-Analytical Evaluation of Amyloid-β Positron Emission Tomography.

J. Seibyl, K. Ishii, P. Cumming, 2020, Journal of Alzheimer's Disease.

Aβ imaging with 18F-florbetaben in prodromal Alzheimer's disease: a prospective outcome study

John Seibyl, Ana M Catafau, Christopher C Rowe, 2014, Journal of Neurology, Neurosurgery & Psychiatry.

Validation of Serum Neurofilament Light Chain as a Biomarker of Parkinson’s Disease Progression

A. Singleton, A. Toga, D. Galasko, 2020, Movement disorders : official journal of the Movement Disorder Society.

Targeting Prodromal Alzheimer Disease With Avagacestat: A Randomized Clinical Trial.

John Seibyl, Vladimir Coric, Hilkka Soininen, 2015, JAMA neurology.

123I-5-IA-85380 SPECT Imaging of Nicotinic Receptors in Alzheimer Disease and Mild Cognitive Impairment

M. Macavoy, J. Seibyl, J. Staley, 2009, Journal of Nuclear Medicine.

beta2-Nicotinic acetylcholine receptor availability during acute and prolonged abstinence from tobacco smoking.

Gilles Tamagnan, Jeffery Batis, Suchitra Krishnan-Sarin, 2009, Archives of general psychiatry.

Nicotinic Receptors in Alzheimer Disease and Mild Cognitive Impairment

M. Macavoy, J. Seibyl, J. Staley, 2009 .

Human Tobacco Smokers in Early Abstinence Have Higher Levels of β2* Nicotinic Acetylcholine Receptors than Nonsmokers

Suchitra Krishnan-Sarin, Peter Jatlow, Edythe D London, 2006, The Journal of Neuroscience.

Quantification of nicotinic acetylcholine receptors in human brain using [123I]5-I-A-85380 SPET

Robert B. Innis, Gilles Tamagnan, John Seibyl, 2003, European Journal of Nuclear Medicine and Molecular Imaging.

Whole-body biodistribution, radiation absorbed dose, and brain SPET imaging with [123I]5-I-A-85380 in healthy human subjects

J. Seibyl, S. Zoghbi, R. Innis, 2002, European Journal of Nuclear Medicine and Molecular Imaging.

Changes in the Cholinergic System between Bipolar Depression and Euthymia as Measured with [123I]5IA Single Photon Emission Computed Tomography

Tristan D. McClure-Begley, J. Seibyl, Z. Bhagwagar, 2013, Biological Psychiatry.

m-Chlorophenylpiperazine effects in neuroleptic-free schizophrenic patients. Evidence implicating serotonergic systems in the positive symptoms of schizophrenia.

S. Woods, G. Aghajanian, J. Krystal, 1993, Archives of general psychiatry.

Effects of Cocaine on Hospital Course in Schizophrenia

S. Southwick, J. Krystal, J. Seibyl, 1993, The Journal of nervous and mental disease.

Longitudinal Analysis of Multiple Neurotransmitter Metabolites in Cerebrospinal Fluid in Early Parkinson's Disease

A. Toga, J. Dukart, D. Galasko, 2021, Movement disorders : official journal of the Movement Disorder Society.

Receiver-Operating-Characteristic Analysis of an Automated Program for Analyzing Striatal Uptake of 123I-Ioflupane SPECT Images: Calibration Using Visual Reads

John Seibyl, Elizabeth Krupinski, George Zubal, 2013, The Journal of Nuclear Medicine Technology.

Increased dopamine transporter availability associated with the 9-repeat allele of the SLC6A3 gene.

Marc Laruelle, Joel Gelernter, John P Seibyl, 2005, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Cryopreservable neutrophil surrogates: granule-poor, motile cytoplasts from polymorphonuclear leukocytes home to inflammatory lesions in vivo.

Eileen O. Smith, J. Seibyl, S. Malawista, 2006, Cell motility and the cytoskeleton.

Single photon emission computed tomographic imaging demonstrates loss of striatal dopamine transporters in Parkinson disease.

M Laruelle, J. Seibyl, M. Laruelle, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Brain SPECT imaging of amphetamine-induced dopamine release in euthymic bipolar disorder patients.

J. Seibyl, D. Charney, R. Innis, 2000, The American journal of psychiatry.

Whole-body biodistribution and dosimetry estimates of a novel radiotracer for imaging of serotonin 4 receptors in brain: [¹⁸F]MNI-698.

J. Seibyl, G. Tamagnan, O. Barret, 2014, Nuclear medicine and biology.

Longitudinal Analyses of Cerebrospinal Fluid α-Synuclein in Prodromal and Early Parkinson’s Disease

A. Singleton, A. Toga, J. Trojanowski, 2019, Movement disorders : official journal of the Movement Disorder Society.

Plasma α-synuclein and cognitive impairment in the Parkinson's Associated Risk Syndrome: A pilot study

D. Jennings, J. Seibyl, K. Marek, 2018, Neurobiology of Disease.

Clinical and Dopamine Transporter Imaging Characteristics of Leucine Rich Repeat Kinase 2 (LRRK2) and Glucosylceramidase Beta (GBA) Parkinson's Disease Participants in the Parkinson's Progression Markers Initiative: A Cross‐Sectional Study

A. Singleton, A. Toga, J. Trojanowski, 2020, Movement disorders : official journal of the Movement Disorder Society.

Clinical and dopamine transporter imaging characteristics of non-manifest LRRK2 and GBA mutation carriers in the Parkinson's Progression Markers Initiative (PPMI): a cross-sectional study

Yen F. Tai, A. Singleton, P. Muglia, 2020, The Lancet Neurology.

Sex differences in availability of β2*-nicotinic acetylcholine receptors in recently abstinent tobacco smokers.

J. Seibyl, M. Picciotto, K. Cosgrove, 2012, Archives of general psychiatry.

123I-5-IA-85380 SPECT Imaging of Nicotinic Acetylcholine Receptor Availability in Nonsmokers: Effects of Sex and Menstrual Phase

John P Seibyl, Sharon Allen, J. Seibyl, 2007, Journal of Nuclear Medicine.

Absence of behavioral sensitization in healthy human subjects following repeated exposure to ketamine

A. Belger, J. Krystal, J. Seibyl, 2005, Psychopharmacology.

Sex‐specific differences in GABAA‐benzodiazepine receptor availability: relationship with sensitivity to pain and tobacco smoking craving

J. Seibyl, K. Cosgrove, J. Staley, 2013, Addiction biology.

Continuous intravenous infusion of iodine-123-IBZM for SPECT determination of human brain dopamine receptor occupancy by antipsychotic agent RWJ-37796.

J. Krystal, J. Seibyl, D. Charney, 1996, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Potential of Low Dose Leuco-Methylthioninium Bis(Hydromethanesulphonate) (LMTM) Monotherapy for Treatment of Mild Alzheimer’s Disease: Cohort Analysis as Modified Primary Outcome in a Phase III Clinical Trial

Giovanni B. Frisoni, John Seibyl, Roger T. Staff, 2017, Journal of Alzheimer's disease : JAD.

Tau PET imaging with 18F-PI-2620 in Patients with Alzheimer Disease and Healthy Controls: A First-in-Humans Study

J. Seibyl, S. de Santi, K. Marek, 2019, The Journal of Nuclear Medicine.

Fragile X Mental Retardation Protein and Cerebral Expression of Metabotropic Glutamate Receptor Subtype 5 in Men with Fragile X Syndrome: A Pilot Study

James Robert Brašić, Samuel D. Martin, D. Jennings, 2022, Brain sciences.

Neuroreceptor SPECT Imaging Ligands

J. Seibyl, S. Ross, 2004 .

Applications of Selected 123 I-Labeled Neuroreceptor SPECT Imaging Ligands

J. Seibyl, S. Ross, 2004 .

Technical overview of brain SPECT imaging: improving acquisition and processing of data.

Gina N Morano, John P Seibyl, J. Seibyl, 2003, Journal of nuclear medicine technology.

Hemi‐parkinsonism due to a midbrain arteriovenous malformation: dopamine transporter imaging

J. Seibyl, J. Friedman, K. Marek, 2001, Movement disorders : official journal of the Movement Disorder Society.

Elevated central serotonin transporter binding availability in acutely abstinent cocaine-dependent patients.

J. Seibyl, J. Staley, L. Jacobsen, 2000, The American journal of psychiatry.

Molecular Neuroimaging of the Dopamine Transporter as a Patient Enrichment Biomarker for Clinical Trials for Early Parkinson's Disease

D. Hill, T. Nicholas, J. Seibyl, 2019, Clinical and translational science.

Age dependence of brain β-amyloid deposition in Down syndrome

M. Sabbagh, D. Jennings, J. Seibyl, 2015, Neurology.

Age dependence of brain β-amyloid deposition in Down syndrome

M. Sabbagh, D. Jennings, J. Seibyl, 2015, Neurology.

Tau deposition patterns are associated with functional connectivity in primary tauopathies

J. Trojanowski, M. Grossman, J. Seibyl, 2022, Nature Communications.

Assessment of heterogeneity and disease onset in the Parkinson's Progression Markers Initiative (PPMI) cohort using the Î±-synuclein seed amplification assay: a cross-sectional study

Yian Ma, D. Galasko, J. Seibyl, 2023, medRxiv.

Conversion to Parkinson Disease in the PARS Hyposmic and Dopamine Transporter–Deficit Prodromal Cohort

D. Jennings, J. Seibyl, A. Siderowf, 2017, JAMA neurology.

Longitudinal follow-up of SWEDD subjects in the PRECEPT Study

A. Lang, D. Jennings, J. Seibyl, 2014, Neurology.

Tibial Bone Lead, but Not Serum Polychlorinated Biphenyl, Concentrations Are Associated With Neurocognitive Deficits in Former Capacitor Workers

J. Seibyl, S. Factor, A. Todd, 2013, Journal of occupational and environmental medicine.

Absence of an apolipoprotein E epsilon4 allele is associated with increased parietal regional cerebral blood flow asymmetry in Alzheimer disease.

M. Macavoy, J. Seibyl, C. V. van Dyck, 1998, Archives of neurology.

Assessment of 18F-PI-2620 as a Biomarker in Progressive Supranuclear Palsy

F. Jessen, K. Bötzel, J. Seibyl, 2020, JAMA neurology.

SPECT imaging with the D(4) receptor antagonist L-750,667 in nonhuman primate brain.

J. Seibyl, J. Staley, R. Innis, 2000, Nuclear medicine and biology.

Alterations of benzodiazepine receptors in type II alcoholic subjects measured with SPECT and [123I]iomazenil.

M Laruelle, J. Krystal, J. Seibyl, 1998, The American journal of psychiatry.

Benzodiazepine receptor deficiency and tinnitus.

J. Seibyl, A. Shulman, B. Goldstein, 2000, The international tinnitus journal.

SNM Practice Guideline for Dopamine Transporter Imaging with 123I-Ioflupane SPECT 1.0*

John Seibyl, Karl Herholz, Osama Sabri, 2012, The Journal of Nuclear Medicine.

Dopamine and serotonin transporters in patients with schizophrenia: an imaging study with [123I]β-CIT

J. Krystal, J. Seibyl, M. Laruelle, 2000, Biological Psychiatry.

The phosphodiesterase 10 positron emission tomography tracer, [18F]MNI-659, as a novel biomarker for early Huntington disease.

D. Jennings, J. Seibyl, J. Friedman, 2014, JAMA neurology.

Cognition in individuals at risk for Parkinson's: Parkinson associated risk syndrome (PARS) study findings

D. Jennings, J. Seibyl, K. Hawkins, 2016, Movement disorders : official journal of the Movement Disorder Society.

Development and In Vivo Preclinical Imaging of Fluorine-18-Labeled Synaptic Vesicle Protein 2A (SV2A) PET Tracers

Christine M Sandiego, Olivier Barret, David Alagille, 2018, Molecular Imaging and Biology.

SNMMI Procedure Standard/EANM Practice Guideline for Amyloid PET Imaging of the Brain 1.0

Koen Van Laere, Osama Sabri, Chester A. Mathis, 2016, The Journal of Nuclear Medicine.

Increase in prefrontal cortex serotonin 2A receptors following estrogen treatment in postmenopausal women.

John P Seibyl, Robert B Innis, Masahiro Fujita, 2003, The American journal of psychiatry.

A Visual Interpretation Algorithm for Assessing Brain Tauopathy with 18F-MK-6240 PET

J. Seibyl, R. Gunn, M. Ichise, 2023, The Journal of Nuclear Medicine.

Kinetic Modeling of the Tau PET Tracer 18F-AV-1451 in Human Healthy Volunteers and Alzheimer Disease Subjects

M. Mintun, D. Jennings, J. Seibyl, 2017, The Journal of Nuclear Medicine.

[123I]Iomazenil SPECT benzodiazepine receptor imaging in schizophrenia

J. Krystal, J. Seibyl, J. Soares, 1999, Psychiatry Research: Neuroimaging.

Binding characteristics of [18F]PI-2620 distinguish the clinically predicted tau isoform in different tauopathies by PET

Özgür A. Onur, F. Jessen, K. Bötzel, 2021, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Displacement of Serotonin and Dopamine Transporters by Venlafaxine Extended Release Capsule at Steady State: A [123I]2β-Carbomethoxy-3β-(4-Iodophenyl)-Tropane Single Photon Emission Computed Tomography Imaging Study

G. Marek, J. Seibyl, K. Marek, 2007, Journal of clinical psychopharmacology.

What Is the Role of Dopamine Transporter Imaging in Parkinson Prevention Clinical Trials?

J. Seibyl, P. Kuo, 2022, Neurology.

Statistical Considerations in the Design of Clinical Trials Targeting Prodromal Parkinson Disease

J. Seibyl, M. Brumm, C. Coffey, 2022, Neurology.

Dopamine and serotonin transporter availability in chronic heroin users: A [123I]β-CIT SPECT imaging study

J. Seibyl, K. Cosgrove, J. Staley, 2010, Psychiatry Research: Neuroimaging.

Elevated Striatal Dopamine Transporters During Acute Cocaine Abstinence as Measured by [123I]β-CIT SPECT

M Laruelle, J. Seibyl, M. Laruelle, 1998, American Journal of Psychiatry.

A Visual Interpretation Algorithm for Assessing Brain Tauopathy with 18F-MK-6240 PET

Jessica A. Collins, J. Seibyl, R. Gunn, 2022, The Journal of Nuclear Medicine.

The molecular basis of dopaminergic brain imaging in Parkinson's disease.

J. Seibyl, K. Marek, D. Russell, 2012, The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of....

J. Seibyl, K. Cosgrove, J. Staley, 2009, Neurobiology of Aging.

Adenosine 2A Receptor Occupancy by Tozadenant and Preladenant in Rhesus Monkeys

J. Seibyl, M. Laruelle, G. Tamagnan, 2014, The Journal of Nuclear Medicine.

Neuroimaging over the course of Parkinson's disease: from early detection of the at-risk patient to improving pharmacotherapy of later-stage disease.

John Seibyl, Danna Jennings, D. Jennings, 2012, Seminars in nuclear medicine.

Opiate dependence and withdrawal: preliminary assessment using single photon emission computerized tomography (SPECT).

S. Woods, J. Krystal, J. Seibyl, 1995, The American journal of drug and alcohol abuse.

Imaging Changes in Synaptic Acetylcholine Availability in Living Human Subjects

Richard E Carson, Marc Laruelle, John P Seibyl, 2013, The Journal of Nuclear Medicine.

Research applications of selected 123I-labeled neuroreceptor SPECT imaging ligands.

J. Seibyl, S. Ross, 2004, Journal of nuclear medicine technology.

Beta-amyloid imaging with florbetaben

C. Rowe, J. Seibyl, O. Sabri, 2015, Clinical and Translational Imaging.

Preclinical properties and human in vivo assessment of 123 I-ABC577 as a novel SPECT agent for imaging amyloid-β

D. Jennings, J. Seibyl, K. Marek, 2015, Brain : a journal of neurology.

Early detection of amyloid load using 18F-florbetaben PET

C. Rowe, J. Seibyl, S. Landau, 2021, Alzheimer's research & therapy.

Selective frontal, parietal, and temporal networks in generalized seizures

Jason Freeman, Colin Studholme, John Seibyl, 2003, NeuroImage.

Serial olfactory testing for the diagnosis of prodromal Parkinson's disease in the PARS study.

C. Adler, D. Jennings, J. Seibyl, 2022, Parkinsonism & related disorders.

In Vivo Assessment and Dosimetry of 2 Novel PDE10A PET Radiotracers in Humans: 18F-MNI-659 and 18F-MNI-654

Olivier Barret, Gilles Tamagnan, John Seibyl, 2014, The Journal of Nuclear Medicine.

Equilibrium modeling of 5-HT(2A) receptors with [18F]deuteroaltanserin and PET: feasibility of a constant infusion paradigm.

J. Seibyl, J. Soares, D. Charney, 2000, Nuclear medicine and biology.

Correlation of florbetaben PET imaging and the amyloid peptide Aß42 in cerebrospinal fluid

J. Seibyl, O. Peters, O. Sabri, 2017, Psychiatry Research: Neuroimaging.

The Role of Quantitative Ictal SPECT Analysis in the Evaluation of Nonepileptic Seizures

J. Seibyl, S. Spencer, M. Spanaki, 1999, Journal of neuroimaging : official journal of the American Society of Neuroimaging.

18F-PI-2620 Tau PET Improves the Imaging Diagnosis of Progressive Supranuclear Palsy

J. Seibyl, M. Schroeter, K. Hoffmann, 2022, The Journal of Nuclear Medicine.

Tauopathy PET and amyloid PET in the diagnosis of chronic traumatic encephalopathies: studies of a retired NFL player and of a man with FTD and a severe head injury

P. Hof, M. Sano, S. DeKosky, 2014, Translational Psychiatry.

Decreased Beta2*‐nicotinic acetylcholine receptor availability after chronic ethanol exposure in nonhuman primates

J. Krystal, J. Seibyl, K. Cosgrove, 2010, Synapse.

Measurement of α4β2 nicotinic acetylcholine receptors with [123I]5-I-A-85380 SPECT

J. Seibyl, S. Zoghbi, R. Innis, 2000 .

Quantification of Smoking-Induced Occupancy of β2-Nicotinic Acetylcholine Receptors: Estimation of Nondisplaceable Binding

J. Seibyl, K. Cosgrove, J. Staley, 2010, The Journal of Nuclear Medicine.

GABAA‐benzodiazepine receptor availability in smokers and nonsmokers: Relationship to subsyndromal anxiety and depression

R. Makuch, J. Seibyl, K. Cosgrove, 2009, Synapse.

Cortical γ-aminobutyric acid type A-benzodiazepine receptors in recovery from alcohol dependence : Relationship to features of alcohol dependence and cigarette smoking

Robert B. Innis, John Seibyl, David Weinzimmer, 2005 .

SPECT imaging of nicotinic acetylcholine receptors in nonsmoking heavy alcohol drinking individuals.

J. Krystal, J. Seibyl, K. Cosgrove, 2010, Drug and alcohol dependence.

Brain β2*-nicotinic acetylcholine receptor occupancy after use of a nicotine inhaler.

J. Seibyl, M. Picciotto, K. Cosgrove, 2011, The international journal of neuropsychopharmacology.

α-Synuclein PET and Parkinson Disease Therapeutic Trials: Ever the Twain Shall Meet?

J. Seibyl, 2022, The Journal of Nuclear Medicine.

Effect of a nicotine vaccine on nicotine binding to β2*-nicotinic acetylcholine receptors in vivo in human tobacco smokers.

J. Seibyl, K. Cosgrove, R. Tyndale, 2013, The American journal of psychiatry.

Sex Differences in Diencephalon Serotonin Transporter Availability in Major Depression

Robert B. Innis, Gilles Tamagnan, John P. Seibyl, 2006, Biological Psychiatry.

Dopamine efflux in response to ultraviolet radiation in addicted sunbed users

H. Jacobe, J. Seibyl, F. Filbey, 2016, Psychiatry Research: Neuroimaging.

Significance of nonuniform attenuation correction in quantitative brain SPECT imaging.

I G Zubal, J. Seibyl, I. Zubal, 1998, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Unaltered dopamine transporter availability in adult attention deficit hyperactivity disorder.

John P Seibyl, Robert B Innis, J. Seibyl, 2002, The American journal of psychiatry.

Brain serotonin transporter availability predicts treatment response to selective serotonin reuptake inhibitors

Robert B. Innis, Amit Anand, John P. Seibyl, 2004, Biological Psychiatry.

Impact of Training Method on the Robustness of the Visual Assessment of 18F-Florbetaben PET Scans: Results from a Phase-3 Study

John Seibyl, Ana M Catafau, Henryk Barthel, 2016, The Journal of Nuclear Medicine.

Test–Retest Reproducibility for the Tau PET Imaging Agent Flortaucipir F 18

M. Mintun, A. Joshi, M. Pontecorvo, 2017, The Journal of Nuclear Medicine.

Human biodistribution and dosimetry of the SPECT benzodiazepine receptor radioligand iodine-123-iomazenil.

J. Seibyl, D. Charney, I. Zubal, 1994, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Pharmacokinetics of the SPECT benzodiazepine receptor radioligand [123I]iomazenil in human and non-human primates.

E. Sybirska, S. Woods, J. Seibyl, 1992, International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology.

γ-Aminobutyric Acid–Serotonin Interactions in Healthy Men: Implications for Network Models of Psychosis and Dissociation

J. Krystal, J. Seibyl, J. Ebersole, 2006, Biological Psychiatry.

Cerebellar Amyloid-β Plaques: How Frequent Are They, and Do They Influence 18F-Florbetaben SUV Ratios?

Osama Sabri, Ana M Catafau, Bernardino Ghetti, 2016, The Journal of Nuclear Medicine.

A novel thermoregulatory role for PDE10A in mouse and human adipocytes

J. Seibyl, Sally Wagner, P. Brust, 2016, EMBO molecular medicine.

Early-phase [18F]PI-2620 tau-PET imaging as a surrogate marker of neuronal injury

Özgür A. Onur, F. Jessen, K. Bötzel, 2020, European Journal of Nuclear Medicine and Molecular Imaging.

[sup 123 I] beta-CIT/SPECT imaging demonstrates bilateral loss of dopamine transporters in hemi-Parkinson's disease

J. P. Seibyl, P. B. Hoffer, J. Seibyl, 1996, Neurology.

Sensitivity and specificity of quantitative difference SPECT analysis in seizure localization.

I G Zubal, J. Seibyl, S. Spencer, 1999, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Effect of injection time on postictal SPET perfusion changes in medically refractory epilepsy

I. George Zubal, Robert A. Avery, John P. Seibyl, 1999, European Journal of Nuclear Medicine.

Whole-body biodistribution, radiation absorbed dose and brain SPECT imaging with iodine-123-beta-CIT in healthy human subjects.

J. Seibyl, S. Zoghbi, R. Baldwin, 1994, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Regional cerebral blood flow during acute and chronic abstinence from combined cocaine-alcohol abuse.

S. Woods, J. Seibyl, L. Price, 1998, Drug and alcohol dependence.

Serum urate as a predictor of clinical and radiographic progression in Parkinson disease.

A. Lang, J. Seibyl, S. Fahn, 2008, Archives of neurology.

Toward a Universal Readout for 18F-Labeled Amyloid Tracers: The CAPTAINs Study

C. Rowe, J. Seibyl, N. Foster, 2021, The Journal of Nuclear Medicine.

Clinical and Imaging Progression in the PARS Cohort: Long‐Term Follow‐up

D. Jennings, J. Seibyl, A. Siderowf, 2020, Movement disorders : official journal of the Movement Disorder Society.

Longitudinal Change of Clinical and Biological Measures in Early Parkinson's Disease: Parkinson's Progression Markers Initiative Cohort

Norbert Schuff, Arthur W. Toga, John Seibyl, 2018, Movement disorders : official journal of the Movement Disorder Society.

Prolonged postictal encephalopathy in two patients with clozapine-induced seizures.

J. Krystal, S. Salloway, J. Seibyl, 1992, The Journal of neuropsychiatry and clinical neurosciences.

[123I]beta-CIT SPECT imaging of striatal dopamine transporter binding in Tourette's disorder.

C. McDougle, J. Seibyl, J. Leckman, 1995, The American journal of psychiatry.

[123I]Iomazenil spect imaging demonstrates significant benzodiazepine receptor reserve in human and nonhuman primate brain

E. Sybirska, J. Seibyl, D. Charney, 1993, Neuropharmacology.

Imaging D2 Receptor Occupancy by Endogenous Dopamine in Humans

Marc Laruelle, Anissa Abi-Dargham, John P Seibyl, 1997, Neuropsychopharmacology.

A practical approach to remote longitudinal follow‐up of Parkinson's disease: The FOUND study

C. Tanner, A. Lang, J. Seibyl, 2014, Movement disorders : official journal of the Movement Disorder Society.

P4-346: Safety, tolerability and biomarker effects of an Abeta monoclonal antibody administered to patients with Alzheimer's disease

E. Siemers, D. Jennings, J. Seibyl, 2008, Alzheimer's & Dementia.

Comparison of Noninvasive Quantification Methods of in Vivo Vesicular Acetylcholine Transporter Using [123I]-IBVM SPECT Imaging

J. Seibyl, M. Allard, O. Barret, 2008, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Multicentre phase 3 trial on florbetaben for beta-amyloid brain PET in Alzheimer's disease

M. Sabbagh, J. Seibyl, B. Ghetti, 2012, Alzheimer's & Dementia.

PET and SPECT in the Evaluation of Patients with Central Motor Disorders

J. Seibyl, 2009 .

Immunohistochemical Method and Histopathology Judging for the Systemic Synuclein Sampling Study (S4)

C. Adler, D. Jennings, J. Seibyl, 2018, Journal of neuropathology and experimental neurology.

Reference region selection and the association between the rate of amyloid accumulation over time and the baseline amyloid burden

J. Seibyl, For the Alzheimer’s Disease Neuroimaging Initiative, A. Rominger, 2017, European Journal of Nuclear Medicine and Molecular Imaging.

Characterization in Humans of 18F-MNI-444, a PET Radiotracer for Brain Adenosine 2A Receptors

D. Jennings, J. Seibyl, M. Laruelle, 2015, The Journal of Nuclear Medicine.

DOPAMINE AND SEROTONIN TRANSPORTER AVAILABILITY DURING ACUTE ALCOHOL WITHDRAWAL: EFFECTS OF COMORBID TOBACCO SMOKING

J. Krystal, J. Seibyl, K. Cosgrove, 2009, Neuropsychopharmacology.

Risk Syndrome Study Imaging prodromal Parkinson disease : The Parkinson Associated

D. Jennings, J. Seibyl, A. Siderowf, 2022 .

[123I]β-CIT SPECT imaging assessment of the rate of Parkinson’s disease progression

J. Seibyl, K. Marek, C. V. van Dyck, 2001, Neurology.

Do dopamine agonists or levodopa modify Parkinson's disease progression?

J. Seibyl, K. Marek, D. Jennings, 2002, European journal of neurology.

24-MONTH AMYLOID PET RESULTS OF THE GANTENERUMAB HIGH-DOSE OPEN LABEL EXTENSION STUDIES

M. Andjelkovic, J. Seibyl, R. Doody, 2018, Alzheimer's & Dementia.

Improved longitudinal [18F]-AV45 amyloid PET by white matter reference and VOI-based partial volume effect correction

John Seibyl, Peter Bartenstein, Axel Rominger, 2015, NeuroImage.

Behavioral Changes and [123I]IBZM Equilibrium SPECT Measurement of Amphetamine-Induced Dopamine Release in Rhesus Monkeys Exposed to Subchronic Amphetamine

P. Goldman-Rakic, J. Seibyl, R. Innis, 2000, Neuropsychopharmacology.

Signs and Artifacts in Amyloid PET.

J. Seibyl, P. Kuo, Tamara F Lundeen, 2018, Radiographics : a review publication of the Radiological Society of North America, Inc.

Valproate in the treatment of temper outbursts.

J. Seibyl, C. Mazure, W. J. Giakas, 1990, The Journal of clinical psychiatry.

Cognition and the course of prodromal Parkinson's disease

D. Jennings, J. Seibyl, K. Hawkins, 2017, Movement disorders : official journal of the Movement Disorder Society.

Prolonged cocaine psychosis implies underlying major psychopathology.

J. Seibyl, D. Charney, S. Satel, 1991, The Journal of clinical psychiatry.

Cerebral Expression of Metabotropic Glutamate Receptor Subtype 5 in Idiopathic Autism Spectrum Disorder and Fragile X Syndrome: A Pilot Study

James Robert Brašić, Samuel D. Martin, D. Jennings, 2021, International journal of molecular sciences.

Beta2* nicotinic acetylcholine receptors modulate pain sensitivity in acutely abstinent tobacco smokers.

J. Seibyl, K. Cosgrove, J. Staley, 2010, Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco.

[123I]beta-CIT SPECT imaging assessment of the rate of Parkinson's disease progression.

J. Seibyl, K. Marek, C. V. van Dyck, 2001, Neurology.

APPLICATION OF A MULTI-ATLAS SEGMENTATION TOOL TO HIPPOCAMPUS, VENTRICLE AND WHOLE BRAIN SEGMENTATION

J. Seibyl, Ali Ghayoor, J. Hesterman, 2017, Alzheimer's & Dementia.

Positron Emission Tomography in Patients With Central Motor Disorders and in Evaluation of Brain and Other Tumors

Wei Chen, John P Seibyl, Daniel H S Silverman, 2007 .

Association between Hoehn and Yahr, Mini-Mental State Examination, age, and clinical syndrome predominance and diagnostic effectiveness of ioflupane I 123 injection (DaTSCAN™) in subjects with clinically uncertain parkinsonian syndromes

A. Kupsch, J. Seibyl, R. Hauser, 2014, Alzheimer's Research & Therapy.

Neuroimaging trials of Parkinson’s disease progression

D. Jennings, J. Seibyl, K. Marek, 2004, Journal of Neurology.

Test/retest reproducibility of iodine-123-betaCIT SPECT brain measurement of dopamine transporters in Parkinson's patients.

P B Hoffer, J. Seibyl, D. Charney, 1997, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Effect of treatment with L‐dopa/carbidopa or L‐selegiline on striatal dopamine transporter SPECT imaging with [123I]β‐CIT

J. Seibyl, K. Marek, S. Zoghbi, 1999, Movement disorders : official journal of the Movement Disorder Society.

Iodine-123-β-CIT and Iodine-123-FPCIT SPECT Measurement of Dopamine Transporters in Healthy Subjects and Parkinson's Patients

Robert B. Innis, John Seibyl, Dennis S. Charney, 1998 .

Dopamine agonists and Parkinson's disease progression: What can we learn from neuroimaging studies

John Seibyl, Danna Jennings, D. Jennings, 2003, Annals of neurology.

Striatal dopamine transporters correlate with simple reaction time in elderly subjects

M. Macavoy, A. Arnsten, J. Seibyl, 2008, Neurobiology of Aging.

Dopamine D1 Receptor Agonist PET Tracer Development: Assessment in Nonhuman Primates

Jenna M. Sullivan, J. Seibyl, G. Tamagnan, 2021, The Journal of Nuclear Medicine.

Reproducibility of in vivo brain measures of 5-HT2A receptors with PET and [18F]deuteroaltanserin

Robert B. Innis, John Seibyl, Sami S. Zoghbi, 2001, Psychiatry Research: Neuroimaging.

Evaluation of an Objective Striatal Analysis Program for Determining Laterality in Uptake of 123I-Ioflupane SPECT Images: Comparison to Clinical Symptoms and to Visual Reads

Elizabeth A. Krupinski, John Seibyl, Phillip H. Kuo, 2014, The Journal of Nuclear Medicine Technology.

Unique roles of SPET brain imaging in clinical and research studies. Lessons from Parkinson's disease research.

J. Seibyl, K. Marek, D. Jennings, 2005, The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of....

(123I) beta-CIT and single-photon emission computed tomographic imaging vs clinical evaluation in Parkinsonian syndrome: unmasking an early diagnosis.

David Oakes, John P Seibyl, D. Jennings, 2004, Archives of neurology.

C. Studholme, J. Seibyl, S. Spencer, 2000, Epilepsia.

SPECT imaging of the benzodiazepine receptor: feasibility of in vivo potency measurements from stepwise displacement curves.

E. Sybirska, J. Seibyl, M. Laruelle, 1991, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Single‐Photon Emission Computed Tomography of the Dopamine Transporter in Parkinsonism

J. Seibyl, 1999, Journal of neuroimaging : official journal of the American Society of Neuroimaging.

Nicotinic Acetylcholine Receptors in Human Brain by the Constant Infusion Paradigm: Feasibility and Reproducibility

J. Seibyl, J. Staley, D. Weinzimmer, 2005 .

Ritanserin antagonism of m-chlorophenylpiperazine effects in neuroleptic-free schizophrenics patients: support for serotonin-2 receptor modulation of schizophrenia symptoms

J. Krystal, J. Seibyl, D. Charney, 2002, Psychopharmacology.

Kinetic modeling and occupancy measures of the norepinephrine transporters in baboons using single photon emission computed tomography with 123I‐INER

J. Seibyl, K. Cosgrove, J. Kordower, 2013, Synapse.

Dynamic SPECT imaging of dopamine D2 receptors in human subjects with iodine-123-IBZM.

S. Woods, J. Seibyl, H. Kung, 1992, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Neuroimaging in Parkinson’s Disease

D. Jennings, J. Seibyl, K. Marek, 2005 .

Diffusion imaging of nigral alterations in early Parkinson's disease with dopaminergic deficits

J. Jankovic, N. Schuff, Z. Mari, 2015, Movement disorders : official journal of the Movement Disorder Society.

[(123)I]beta-CIT SPECT imaging demonstrates reduced density of striatal dopamine transporters in Parkinson's disease and multiple system atrophy.

J. Seibyl, K. Marek, R. Innis, 2001, Movement disorders : official journal of the Movement Disorder Society.

[123I] beta-CIT/SPECT imaging demonstrates bilateral loss of dopamine transporters in hemi-Parkinson's disease.

P B Hoffer, J. Seibyl, D. Charney, 1996, Neurology.

Impact of the Dopamine System on Long‐Term Cognitive Impairment in Parkinson Disease: An Exploratory Study

Michele T. M. Hu, Yen F. Tai, Z. Mari, 2023, Movement disorders clinical practice.

Partial-Volume Effect Correction Improves Quantitative Analysis of 18F-Florbetaben β-Amyloid PET Scans

John Seibyl, Marianne Patt, Osama Sabri, 2016, The Journal of Nuclear Medicine.

Cross-Sectional and Longitudinal Validation of Serum Neurofilament Light Chain (NfL) as a Biomarker of Parkinson’s Disease Progression

A. Singleton, A. Toga, D. Galasko, 2019, bioRxiv.

Assessment of heterogeneity among participants in the Parkinson's Progression Markers Initiative cohort using α-synuclein seed amplification: a cross-sectional study

C. Tanner, J. Seibyl, Douglas Galasko, 2023, The Lancet Neurology.

Kinetic Modeling, Test–Retest, and Dosimetry of 123I-MNI-420 in Humans

D. Jennings, J. Seibyl, I. Zubal, 2013, The Journal of Nuclear Medicine.

In vivo evaluation of [(123)I]MNI-420: a novel single photon emission computed tomography radiotracer for imaging of adenosine 2A receptors in brain.

J. Seibyl, K. Cosgrove, J. Kordower, 2013, Nuclear medicine and biology.

Sensitivity, Specificity, Positive and Negative Predictive Values and Diagnostic Accuracy of DaTscan™ (Ioflupane I123 Injection): Predicting Clinical Diagnosis in Early Clinically Uncertain Parkinsonian Syndrome

A. Kupsch, J. Seibyl, R. Hauser, 2014 .

Probing GABA Receptor Function in Schizophrenia with Iomazenil

John Seibyl, Roberto Gil, Deepak Cyril D'Souza, 2011, Neuropsychopharmacology.

Clinical utility of DaTscan™ imaging in the evaluation of patients with parkinsonism: a US perspective

J. Seibyl, R. Pahwa, K. Marek, 2017, Expert review of neurotherapeutics.

Contents of the Journal of Nervous and Mental Disease

Dominic, R. Kessler, S. Southwick, 1993, Psychological Medicine.

Change in PDE10 across early Huntington disease assessed by [18F]MNI-659 and PET imaging

D. Jennings, J. Seibyl, K. Marek, 2016, Neurology.

Exploiting the Full Potential of β-Amyloid and Tau PET Imaging for Drug Efficacy Testing

J. Seibyl, A. Lammertsma, V. Villemagne, 2020, The Journal of Nuclear Medicine.

Florbetaben for beta-amyloid brain PET in Alzheimer's disease: Results of a multicenter phase 2 trial

I. Heuser, J. Seibyl, H. Gertz, 2010, Alzheimer's & Dementia.

Clinical Research Effects of Vigabatrin on the GABAergic System as Determined by ('231)Iomazenil SPECT and GABA MRS

R. Mattson, F. Hyder, J. Seibyl, 1999 .

Influence of technetium-99m-hexamethylpropylene amine oxime injection time on single-photon emission tomography perfusion changes in epilepsy

I. G. Zubal, J. P. Seibyl, M. V. Spanaki, 1999, European Journal of Nuclear Medicine.

Regional brain uptake and pharmacokinetics of [123I]N-ω -fluoroalkyl-2β-carboxy-3β-(4-iodophenyl) nortropane esters in baboons

J. Seibyl, D. Charney, S. Zoghbi, 1995 .

Evolution and Localization of Postictal Blood Flow Changes in Partial Seizures Demonstrated by SPECT: Use of Quantitative Difference Images

J. Seibyl, S. Spencer, I. Zubal, 1998 .

SPECT imaging of the benzodiazepine receptor in non-human primate brain with [123I]Ro 16-0154.

S. Woods, J. Seibyl, D. Charney, 1991, European journal of pharmacology.

“Central” and “peripheral” benzodiazepine receptors

D. Spencer, R. Mattson, J. Seibyl, 1992, Neurology.

FIRST-IN-HUMAN PET STUDIES WITH THE NEXT GENERATION TAU AGENT 18-F PI-2620 IN ALZHEIMER’S DISEASE, PROGRESSIVE SUPRANUCLEAR PALSY, AND CONTROLS

J. Seibyl, K. Marek, L. Dinkelborg, 2017, Alzheimer's & Dementia.

Correction for Crosstalk Contaminations in Dual Radionuclide and Images Using Artificial Neural Network

Michael A. King, Xiaoming Zheng, I. G. Zubal, 2004 .

[123I]5‐IA‐85380 SPECT Imaging of β2‐Nicotinic Acetylcholine Receptor Availability in the Aging Human Brain

J. Seibyl, K. Cosgrove, J. Staley, 2007, Annals of the New York Academy of Sciences.

Imaging studies in movement disorders.

J. Seibyl, 2003, Seminars in nuclear medicine.

Characterization of the dopamine transporter in nonhuman primate brain: homogenate binding, whole body imaging, and ex vivo autoradiography using [125I] and [123I]IPCIT.

J. Seibyl, D. Charney, M. Laruelle, 1995, Nuclear medicine and biology.

Assessment of Parkinson disease progression using 123- I I-Ioflupane SPECT: Update from the Parkinson Progression Marker Initiative Trial (I11-5C)

D. Jennings, J. Seibyl, K. Marek, 2015 .

MCPP effects in schizophrenic patients before and after typical and atypical neuroleptic treatment

S. Woods, J. Krystal, J. Seibyl, 1991, Schizophrenia Research.

Dynamic SPECT imaging after injection of the benzodiazepine receptor ligand [123I]iomazenil in healthy human subjects

Eileen O. Smith, S. Woods, J. Seibyl, 1992, Psychiatry Research: Neuroimaging.

Imaging Dopamine Transporters in Parkinson’s Disease and Other Movement Disorders

J. Seibyl, 2003 .

Imaging the dopamine system to assess disease-modifying drugs

D. Jennings, J. Seibyl, K. Marek, 2003, Neurology.

Elevated central levels of interleukin-2 in drug-free schizophrenic patients

J. Krystal, J. Licinio, J. Seibyl, 1991, Schizophrenia Research.

Plasma homovanillic acid and the dopamine transporter during cocaine withdrawal

J. Seibyl, T. Kosten, M. Bowers, 1998, Biological Psychiatry.

Accuracy of DaTscan™ (Ioflupane I 123 Injection) in diagnosis of early parkinsonian syndromes (PS)

J. Seibyl, K. Marek, R. Hauser, 2013 .

Test-retest reproducibility of extrastriatal dopamine D2 receptor imaging with [123I]epidepride SPECT in humans.

M Fujita, J. Seibyl, D. Charney, 2000, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Kinetic and equilibrium analyses of [123I]epidepride binding to striatal and extrastriatal dopamine D2 receptors

Robert B. Innis, John Seibyl, Masanori Ichise, 1999 .

Cortical gamma-aminobutyric acid type A-benzodiazepine receptors in recovery from alcohol dependence: relationship to features of alcohol dependence and cigarette smoking.

David Weinzimmer, John H Krystal, Peter Jatlow, 2005, Archives of general psychiatry.

Drisapersen treatment for Duchenne muscular dystrophy: results of a 96-week follow-up of an open-label extension study following two placebo-controlled trials

Katie, M. Brin, C. Rowe, 2014 .

Neurotheranostics: The Next Frontier for Health Span.

J. Seibyl, P. Kuo, Meryam A Losee, 2023, Journal of Nuclear Medicine Technology.

Imaging Biomarkers for Central Nervous System Drug Development and Future Clinical Utility: Lessons from Neurodegenerative Disorders

J. Seibyl, 2022, The Journal of Nuclear Medicine.

Measurement of alpha4beta2 nicotinic acetylcholine receptors with [123I]5-I-A-85380 SPECT.

J. Seibyl, S. Zoghbi, R. Innis, 2000, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Graphical analysis and simplified quantification of striatal and extrastriatal dopamine D2 receptor binding with [123I]epidepride SPECT.

J. Seibyl, D. Charney, R. Innis, 1999, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Cerebral benzodiazepine receptors in depressed patients measured with [123i]iomazenil SPECT

A. Anand, J. Seibyl, D. Charney, 2003, Biological Psychiatry.

Spect imaging of the benzodiazepine receptor in humans using [123I]iomazenil

J. Krystal, J. Seibyl, D. Charney, 1993, Schizophrenia Research.

Sensitivity, specificity, positive and negative predictive values and accuracy of datscan™/INS; for prediction of clinical diagnosis of early parkinsonian syndromes

A. Kupsch, J. Seibyl, K. Marek, 2013, Journal of the Neurological Sciences.

Serum urate as a predictor of clinical and radiographic progression in Parkinson disease.

A. Lang, J. Seibyl, S. Fahn, 2008, Archives of neurology.

Development of SPECT imaging agents for the norepinephrine transporters: [123I]INER.

F. Tarazi, R. Baldessarini, J. Seibyl, 2007, Bioorganic & medicinal chemistry letters.

Dopamine efflux in response to ultraviolet radiation in addicted sunbed users

H. Jacobe, J. Seibyl, F. Filbey, 2016, Psychiatry Research: Neuroimaging.

Effect of scatter correction on the compartmental measurement of striatal and extrastriatal dopamine D2 receptors using [123I]epidepride SPET

Robert B. Innis, Sami S. Zoghbi, Nicholas Seneca, 2004, European Journal of Nuclear Medicine and Molecular Imaging.

J. Seibyl, M. Laruelle, S. Zoghbi, 2002, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Quantitation of glutamate mGluR5 receptor with 18F-FPEB PET in humans

Olivier Barret, Gilles Tamagnan, Jeffery Batis, 2010, NeuroImage.

Benzodiazepine receptor distribution in severe intractable tinnitus.

John P Seibyl, Sami S Zoghbi, J. Seibyl, 2004, The international tinnitus journal.

J. Seibyl, K. Cosgrove, J. Staley, 2009, Neurobiology of Aging.

123I-5-IA-85380 SPECT Imaging of Nicotinic Receptors in Alzheimer Disease and Mild Cognitive Impairment

M. Macavoy, J. Seibyl, J. Staley, 2009, Journal of Nuclear Medicine.

SNMMI Procedure Standard/EANM Practice Guideline for Amyloid PET Imaging of the Brain 1.0

N. Bohnen, J. Seibyl, C. Mathis, 2016, The Journal of Nuclear Medicine.

Evaluation of Dosimetry, Quantitative Methods, and Test–Retest Variability of 18F-PI-2620 PET for the Assessment of Tau Deposits in the Human Brain

J. Seibyl, K. Marek, L. Dinkelborg, 2019, The Journal of Nuclear Medicine.

Kinetic and equilibrium analyses of [(123)I]epidepride binding to striatal and extrastriatal dopamine D(2) receptors.