M. Tymms

发表

M. Tymms, I. Kola, 2001 .

The Ets1 transcription factor is widely expressed during murine embryo development and is associated with mesodermal cells involved in morphogenetic processes such as organ formation.

M. Tymms, I. Kola, A. Green, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Protein Synthesis in the Desiccation Tolerant Angiosperm Xerophyta villosa during Dehydration

M. Tymms, D. Gaff, N. Hallam, 1982 .

ETS1 transactivates the human GM-CSF promoter in Jurkat T cells stimulated with PMA and ionomycin.

M. F. Shannon, M. Tymms, A. Seth, 1995, Oncogene.

ETS1, NFkappaB and AP1 synergistically transactivate the human GM-CSF promoter.

M. F. Shannon, M. Tymms, A. Seth, 1997, Oncogene.

Random amplified polymorphic DNA and plasmid analyses used in investigation of an outbreak of multiresistant Klebsiella pneumoniae

M. Tymms, J. Turnidge, D. Eisen, 1995, Journal of clinical microbiology.

G2/M checkpoint gene expression in developing germ cells

M. Tymms, J. Hutson, M. Peart, 2007, Molecular reproduction and development.

Sorsby's fundus dystrophy: what does TIMP3 tell us about general mechanisms underlying macular degeneration?

M. Tymms, 1999, Clinical & experimental optometry.

Expression of the ETS transcription factor ELF3 in the retinal pigment epithelium.

M. Tymms, A. Jobling, D. Koleski, 2002, Investigative ophthalmology & visual science.

A gene on human chromosome 21 located in the region 21q22.2 to 21q22.3 encodes a factor necessary for signal transduction and antiviral response to type I interferons.

M. Tymms, I. Kola, S. Hwang, 1994, The Journal of biological chemistry.

In vitro promoter analysis using nuclear extracts and G-free cassette vectors.

M. Tymms, 2000, Methods in molecular biology.

Homology between 4.3 μm minicircular and plastomic DNA in chloroplasts of Acetabularia cliftonii

M. Tymms, H. Schweiger, C. Ebert, 1985, Molecular and General Genetics MGG.

Antiviral and Antiproliferative Activities of Interferon-α1: The Role of Cysteine Residues

M. Tymms, P. Hertzog, A. Linnane, 1986 .

Quantitative measurement of mRNA using the RNase protection assay.

M. Tymms, 1995, Methods in molecular biology.

Efficient in vitro expression of interferon alpha analogs using SP6 polymerase and rabbit reticulocyte lysate.

M. Tymms, B. McInnes, 1988, Gene analysis techniques.

DNA Content of Beta vulgaris Chloroplasts during Leaf Cell Expansion.

M. Tymms, N. Scott, J. Possingham, 1983, Plant physiology.

Structure-function studies of human interferons-α: Enhanced activity on human and murine cells

M. Tymms, T. Mantamadiotis, P. Murray, 1991 .

Structure-function studies of interferon-α based on random mutagenesis and expression in vitro☆

M. Tymms, A. Linnane, B. F. Cheetham, 1990 .

Functional significance of amino acid residues within conserved hydrophilic regions in human interferons-alpha.

M. Tymms, A. Linnane, B. F. Cheetham, 1989, Antiviral research.

Conserved amino acid residues arginine 33 and tyrosine 123 are critical for the antiviral activity of murine interferon-alpha 1.

M. Tymms, A. Linnane, J. Kerry, 1988, Biochemical and biophysical research communications.

Amino Acid Residues Affecting Antiviral and Antiproliferative Activity in Interferon-α’s

M. Tymms, P. Hertzog, P. Chambers, 1987 .

Regulation of Pdha-2 expression is mediated by proximal promoter sequences and CpG methylation

M. Tymms, I. Kola, M. Hedger, 1997, Molecular and cellular biology.

A Type I Interferon Signaling Factor, ISF21, Encoded on Chromosome 21 Is Distinct from Receptor Components and Their Down-regulation and Is Necessary for Transcriptional Activation of Interferon-regulated Genes*

M. Tymms, I. Kola, S. Constantinescu, 1997, The Journal of Biological Chemistry.

In Vitro Translation

M. Tymms, 1998 .

Chloroplast and Nuclear DNA Content of Cultured Spinach Leaf Discs

M. Tymms, N. Scott, J. Possingham, 1982 .

The role of Ets-1 in mast cell granulocyte-macrophage colony-stimulating factor expression and activation.

M. Tymms, P. Hertzog, A. Seth, 1998, Journal of immunology.

Influence of nucleotides flanking the ggaa core sequence on ets1 and ets2 DNA-binding activity and the mechanism of ets1 autoregulation.

M. Tymms, A. Seth, R. Ramsay, 1992, International journal of oncology.

Human ERG is a proto-oncogene with mitogenic and transforming activity.

A. Hart, M. Tymms, I. Kola, 1995, Oncogene.

Pharmacokinetics, tissue distribution, and cell localization of [35S]methionine-labeled recombinant human and murine alpha interferons in mice.

I. Mackay, M. Tymms, P. Hertzog, 1990, Cancer research.

Pharmacokinetics, tissue distribution, and cell localization of [35S]methionine-labeled recombinant human and murine alpha interferons in mice.

I. Mackay, M. Tymms, P. Hertzog, 1990, Cancer research.

Proline Accumulation during Water Stress in Resurrection Plants

M. Tymms, D. Gaff, 1979 .

Down's syndrome-like skeletal abnormalities in Ets2 transgenic mice

M. Tymms, I. Kola, T. Wilson, 1996, Nature.

Expression of Copper/Zinc Superoxide Dismutase and Glutathione Peroxidase in Organs of Developing Mouse Embryos, Fetuses, and Neonates

M. Tymms, I. Kola, J. Haan, 1994, Pediatric Research.

Plastid-DNA levels in the different tissues of potato

M. Tymms, N. Scott, J. Possingham, 2004, Planta.

A null mutation in the gene encoding a type I interferon receptor component eliminates antiproliferative and antiviral responses to interferons alpha and beta and alters macrophage responses.

M. Tymms, I. Kola, S. Hwang, 1995, Proceedings of the National Academy of Sciences of the United States of America.

A novel epithelial-expressed ETS gene, ELF3: human and murine cDNA sequences, murine genomic organization, human mapping to 1q32.2 and expression in tissues and cancer

Martin Rosenberg, M. Tymms, I. Kola, 1997, Oncogene.

Xenome—a tool for classifying reads from xenograft samples

Jeremy Wazny, Thomas C. Conway, Bryan Beresford-Smith, 2012, Bioinform..

Intratumor MAPK and PI3K signaling pathway heterogeneity in glioblastoma tissue correlates with CREB signaling and distinct target gene signatures.

S. Stylli, A. Kaye, M. Tymms, 2018, Experimental and molecular pathology.

Intratumoral MAPK and PI3K signaling pathway heterogeneity in glioblastoma tissue correlates with selective CREB signaling and specific functional gene signatures

S. Stylli, A. Kaye, M. Tymms, 2018, bioRxiv.

A model for understanding gene regulation during spermatogenesis: the mouse testis Pdha-2 promoter.

M. Tymms, I. Kola, S. Sumarsono, 1995, Reproduction, fertility, and development.

Mouse testis Pdha-2 promoter upstream sequences confer tissue-and temporal-specific activity in transgenic mice.

M. Tymms, I. Kola, S. Sumarsono, 1994, Reproduction, fertility, and development.

Construction of a mouse blastocyst cDNA library by PCR amplification from total RNA

M. Tymms, I. Kola, C. Corrick, 1996, Molecular reproduction and development.

Structure-function study of the region encompassing residues 26-40 of human interferon-alpha 4: identification of residues important for antiviral and antiproliferative activities.

M. Tymms, A. Linnane, B. F. Cheetham, 1992, Journal of interferon research.

In Vitro Transcriptions

M. Tymms, 1998 .

The Elf group of Ets-related transcription factors. ELF3 and ELF5.

M. Tymms, I. Kola, J. Zhou, 2000, Advances in experimental medicine and biology.

A novel transcription factor, ELF5, belongs to the ELF subfamily of ETS genes and maps to human chromosome 11p13–15, a region subject to LOH and rearrangement in human carcinoma cell lines

Lars S Jermiin, M. Tymms, I. Kola, 1998, Oncogene.

The chromosome 21 transcription factor ETS2 transactivates the beta-APP promoter: implications for Down syndrome.

M. Tymms, I. Kola, P. Hertzog, 2003, Biochimica et biophysica acta.

ETS1, NFκB and AP1 synergistically transactivate the human GM – CSF promoter

M. F. Shannon, M. Tymms, Ross S. Thomas, 1997, Oncogene.

Localization of four human chromosome 21 genes--SOD1, ETS2, IFNAR, and CBR--to two different chromosomes in the marsupial species Macropus eugenii.

J. Graves, M. Tymms, S. Brookes, 1992, Cytogenetics and cell genetics.

Structure–Function Studies of Interferons-α: Amino Acid Substitutions at the Conserved Residue Tyrosine 123 in Human Interferon-α1

M. Tymms, P. Chambers, B. F. Cheetham, 1989 .

Human aminopeptidase B (rnpep) on chromosome 1q32.2: complementary DNA, genomic structure and expression.

M. Tymms, C. Piesse, T. Foulon, 2002, Gene.

Amino acid substitutions which alter the antiviral activity of human interferon-alpha 1 on mouse cells.

M. Tymms, P. Pitha-Rowe, P. Chambers, 1988, Journal of Interferon Research.

Tandemly repeated nonribosomal DNA sequences in the chloroplast genome of an Acetabularia mediterranea strain.

M. Tymms, H. Schweiger, 1985, Proceedings of the National Academy of Sciences of the United States of America.