N. Ariel

发表

Comparison of sequence and structure alignments for protein domains

A. Panchenko, A. Marchler-Bauer, S. Bryant, 2002, Proteins.

Genome-Based Bioinformatic Selection of Chromosomal Bacillus anthracis Putative Vaccine Candidates Coupled with Proteomic Identification of Surface-Associated Antigens

K. Makarova, N. Ariel, A. Zvi, 2003, Infection and Immunity.

Whole genome identification of Mycobacterium tuberculosis vaccine candidates by comprehensive data mining and bioinformatic analyses

N. Ariel, A. Zvi, A. Shafferman, 2008, BMC Medical Genomics.

A Rapid Molecular Test for Determining Yersinia pestis Susceptibility to Ciprofloxacin by the Quantification of Differentially Expressed Marker Genes

N. Ariel, A. Zvi, O. Shifman, 2016, Front. Microbiol..

The aromatic "trapping" of the catalytic histidine is essential for efficient catalysis in acetylcholinesterase.

Avigdor Shafferman, Dov Barak, N. Ariel, 2002, Biochemistry.

Orchestration of the functional subsites in the acetylcholinesterase active center – contribution to catalytic perfection and high reactivity toward specific ligands

N. Ariel, A. Shafferman, B. Velan, 2005 .

Silico and In Vitro Screening Virulence Plasmid pXO 1 : In anthracis Bacillus Open Reading Frames in the Search for Potential Vaccine Candidate

N. Ariel, A. Zvi, A. Shafferman, 2002 .

Substrate inhibition of acetylcholinesterase: residues affecting signal transduction from the surface to the catalytic center.

N. Ariel, A. Shafferman, S. Cohen, 1992, The EMBO journal.

The solute‐binding component of a putative Mn(II) ABC transporter (MntA) is a novel Bacillus anthracis virulence determinant

N. Ariel, A. Shafferman, T. Chitlaru, 2005, Molecular microbiology.

Does Electrostatic Attraction or Steering by Charged Residues within the Gorge Contribute to the Reactivity of AChE

N. Ariel, A. Shafferman, B. Velan, 1998 .

Allosteric modulation of acetylcholinesterase activity by peripheral ligands involves a conformational transition of the anionic subsite.

N. Ariel, A. Shafferman, B. Velan, 1995, Biochemistry.

Dissection of the human acetylcholinesterase active center determinants of substrate specificity. Identification of residues constituting the anionic site, the hydrophobic site, and the acyl pocket.

N. Ariel, A. Shafferman, S. Cohen, 1993, The Journal of biological chemistry.

The 'aromatic patch' of three proximal residues in the human acetylcholinesterase active centre allows for versatile interaction modes with inhibitors.

N. Ariel, A. Shafferman, B. Velan, 1998, The Biochemical journal.

Data Mining, Bioinformatic and Immunoinformatic Analyses of Francisella tularensis Schu S4 Genome in Search for Novel Vaccine Candidates

N. Ariel, A. Zvi, A. Shafferman, 2010 .

Generation of Yersinia pestis Attenuated Strains by Signature-Tagged Mutagenesis in Search of Novel Vaccine Candidates

N. Ariel, A. Zvi, A. Shafferman, 2004, Infection and Immunity.

Reverse Vaccinology in Bacillus anthracis

N. Ariel, A. Zvi, A. Shafferman, 2010 .

Membrane anchors of vesicular stomatitis virus: characterization and incorporation into virions

N. Ariel, S. S. Chen, A. Huang, 1988, Journal of virology.

MembraneAnchors ofVesicular Stomatitis Virus: Characterization andIncorporation into Virions

N. Ariel, L. Chen, 1988 .

Acetylcholinesterase Catalysis - Protein Engineering Studies

N. Ariel, A. Shafferman, B. Velan, 1992 .

Surprising findings from the functional analysis of human acetylcholinesterase adducts of Alzheimer’s disease drugs

N. Ariel, A. Shafferman, B. Velan, 2004 .

Structural and Functional Correlates of Human Acetylcholinesterase Mutants for Evaluating Alzheimer’s Disease Treatments

N. Ariel, A. Shafferman, B. Velan, 2002 .

Contribution of the Active Center Functional Architecture to AChE Reactivity Toward Substrates and Inhibitors

N. Ariel, A. Shafferman, B. Velan, 1998 .

Molecular Aspects of Catalysis and of Allosteric Regulation of Aceytlcholinesterases

N. Ariel, S. Reuveny, A. Shafferman, 1995 .

Does "butyrylization" of acetylcholinesterase through substitution of the six divergent aromatic amino acids in the active center gorge generate an enzyme mimic of butyrylcholinesterase?

N. Ariel, A. Shafferman, B. Velan, 2001, Biochemistry.

Exploring the active center of human acetylcholinesterase with stereomers of an organophosphorus inhibitor with two chiral centers.

N. Ariel, A. Shafferman, B. Velan, 1999, Biochemistry.

Engineering resistance to ‘aging’ of phosphylated human acetylcholinesterase Role of hydrogen bond network in the active center

N. Ariel, A. Shafferman, B. Velan, 1993, FEBS letters.

Mutagenesis of human acetylcholinesterase. Identification of residues involved in catalytic activity and in polypeptide folding.

N. Ariel, A. Shafferman, S. Cohen, 1992, The Journal of biological chemistry.

Structures of recombinant native and E202Q mutant human acetylcholinesterase complexed with the snake-venom toxin fasciculin-II.

N. Ariel, J. Sussman, I. Silman, 2000, Acta crystallographica. Section D, Biological crystallography.

Functional Characteristics of the Oxyanion Hole in Human Acetylcholinesterase*

B Velan, N. Ariel, A. Shafferman, 1998, The Journal of Biological Chemistry.

The Architecture of Human Acetylcholinesterase Active Center Probed by Interactions with Selected Organophosphate Inhibitors

B Velan, N. Ariel, A. Shafferman, 1996, The Journal of Biological Chemistry.

Serologically defined linear epitopes in the E2 envelope glycoprotein of Semliki Forest virus

B. Lachmi, N. Ariel, A. Shafferman, 2005, Archives of Virology.

[3] Radioimmunoassay of carcinoembryonic antigen

N. Ariel, M. Krantz, S. Laferté, 1982 .

Identification of Surface-Associated Antigens Vaccine Candidates Coupled with Proteomic Putative Bacillus anthracis Chromosomal Genome-Based Bioinformatic Selection of

K. Makarova, N. Ariel, A. Zvi, 2003 .

Search for Potential Vaccine Candidate Open Reading Frames in the Bacillus anthracis Virulence Plasmid pXO1: In Silico and In Vitro Screening

N. Ariel, A. Zvi, A. Shafferman, 2002, Infection and Immunity.

Search for Bacillus anthracis Potential Vaccine Candidates by a Functional Genomic-Serologic Screen

N. Ariel, A. Zvi, A. Shafferman, 2006, Infection and Immunity.

Differential Proteomic Analysis of the Bacillus anthracis Secretome: Distinct Plasmid and Chromosome CO2-Dependent Cross Talk Mechanisms Modulate Extracellular Proteolytic Activities

N. Ariel, A. Shafferman, T. Chitlaru, 2006, Journal of bacteriology.

Identification of strain specific markers in Bacillus anthracis by random amplification of polymorphic DNA.

N. Ariel, D. Kobiler, Z. Altboum, 2005, FEMS microbiology letters.

Disruption of the NlpD lipoprotein of the plague pathogen Yersinia pestis affects iron acquisition and the activity of the twin-arginine translocation system

N. Ariel, A. Zvi, A. Zauberman, 2019, PLoS neglected tropical diseases.

Aging of phosphylated human acetylcholinesterase: catalytic processes mediated by aromatic and polar residues of the active centre.

N. Ariel, A. Shafferman, B. Velan, 1996, The Biochemical journal.

Electrostatic attraction by surface charge does not contribute to the catalytic efficiency of acetylcholinesterase.

N. Ariel, A. Shafferman, B. Velan, 1994, The EMBO journal.

Acetylcholinesterase peripheral anionic site degeneracy conferred by amino acid arrays sharing a common core.

N. Ariel, A. Shafferman, B. Velan, 1994, The Journal of biological chemistry.

Contribution of Aromatic Moieties of Tyrosine 133 and of the Anionic Subsite Tryptophan 86 to Catalytic Efficiency and Allosteric Modulation of Acetylcholinesterase (*)

N. Ariel, A. Shafferman, B. Velan, 1995, The Journal of Biological Chemistry.

Bovine acetylcholinesterase: cloning, expression and characterization.

N. Ariel, A. Shafferman, B. Velan, 1998, The Biochemical journal.

Identification of genes involved in Yersinia pestis virulence by signature-tagged mutagenesis.

N. Ariel, A. Zvi, A. Shafferman, 2003, Advances in experimental medicine and biology.

What can be Learned from the use of HuAChE Mutants for Evaluation of Potential Alzheimer’s Drugs

N. Ariel, A. Shafferman, B. Velan, 1998 .

Structural modifications of the Ω loop in human acetylcholinesterase

N. Ariel, A. Shafferman, B. Velan, 1996 .

Direct observation and elucidation of the structures of aged and nonaged phosphorylated cholinesterases by 31P NMR spectroscopy.

N. Ariel, Y. Ashani, B. P. Doctor, 1993, Biochemistry.

Molecular Models for Human AChE and its Phosphonylation Products

N. Ariel, A. Shafferman, B. Velan, 1992 .

Effects of transport inhibitors on the generation and transport of a soluble viral glycoprotein.

N. Ariel, S. S. Chen, A. Huang, 1987, Virology.

A Rapid Method for Bacillus anthracis Genotyping

N. Ariel, A. Zvi, D. Kobiler, 2010 .

Development of monoclonal antibodies directed against carcinoembryonic antigen (CEA) and their application for CEA detection

N. Ariel, S. Reuveny, Sara B. Cohen, 1987 .

Production of carcinoembryonic antigen from a human colon adenocarcinoma cell line. II. Use of monoclonal antibodies to carcinoembryonic antigen for antigen purification and characterization.

N. Ariel, S. Reuveny, D. Marcus, 1987, Developments in biological standardization.

Isolation of Anti-Ricin Protective Antibodies Exhibiting High Affinity from Immunized Non-Human Primates

N. Ariel, A. Zvi, O. Mazor, 2016, Toxins.

Genetic Detection of Vesicle Forming Pathogens by Arrayed Primer Extension (APEX)

N. Ariel, A. Zvi, O. Shifman, 2010 .

Differences Amoung Individual CEA Preparations and Carcinomas of Different Origin as Detected by Monoclonal Anti-CEA Antibodies

N. Ariel, Z. Eshhar, R. Arnon, 1984 .

Structures of recombinant native and E202Q mutant human acetylcholinesterase complexed with the snake-venom toxin fasciculin-II.

N. Ariel, J. Sussman, I. Silman, 2000, Acta crystallographica. Section D, Biological crystallography.

Aging of somanyl-acetylcholinesterase adducts: facts and models.

N. Ariel, A. Shafferman, B. Velan, 1997, The Biochemical journal.