I. Wilson

Slawomir K. Grzechnik, Mitchell D. Miller, K. D. Murphy, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

The crystal structure of a bacterial Sufu-like protein defines a novel group of bacterial proteins that are similar to the N-terminal domain of human Sufu

Mitchell D. Miller, A. Godzik, A. Deacon, 2010, Protein science : a publication of the Protein Society.

Structure of the first representative of Pfam family PF04016 (DUF364) reveals enolase and Rossmann-like folds that combine to form a unique active site with a possible role in heavy-metal chelation

Mitchell D. Miller, A. Godzik, A. Deacon, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structural Biology and Crystallization Communications Structures of the First Representatives of Pfam Family Pf06938 (duf1285) Reveal a New Fold with Repeated Structural Motifs and Possible Involvement in Signal Transduction

Mitchell D. Miller, A. Godzik, A. Deacon, 2022 .

Structure of Thermotoga maritima TM0439: implications for the mechanism of bacterial GntR transcription regulators with Zn2+-binding FCD domains.

I. Wilson, D. Giedroc, L. Hung, 2009, Acta crystallographica. Section D, Biological crystallography.

Crystal structure of an alanine‐glyoxylate aminotransferase from Anabaena sp. at 1.70 Å resolution reveals a noncovalently linked PLP cofactor

Adam Godzik, Henry van den Bedem, Slawomir K. Grzechnik, 2005, Proteins.

Getting into the groove: unusual features of peptide binding to MHC class I molecules and implications in vaccine design.

V. Apostolopoulos, I. Wilson, I. McKenzie, 2001, Frontiers in bioscience : a journal and virtual library.

Crystal structure of an ADP‐ribosylated protein with a cytidine deaminase‐like fold, but unknown function (TM1506), from Thermotoga maritima at 2.70 Å resolution

Adam Godzik, Henry van den Bedem, Slawomir K. Grzechnik, 2008, Proteins.

XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators.

Adam Godzik, Ian A Wilson, Barbara J Meyer, 2003, Genes & development.

Crystal structure of a metal‐dependent phosphoesterase (YP_910028.1) from Bifidobacterium adolescentis: Computational prediction and experimental validation of phosphoesterase activity

Adam Godzik, Mary Jo Ondrechen, Hsiu-Ju Chiu, 2011, Proteins.

Crystal structure of the first eubacterial Mre11 nuclease reveals novel features that may discriminate substrates during DNA repair.

John A Tainer, Adam Godzik, Henry van den Bedem, 2010, Journal of molecular biology.

Crystal structure of a zinc‐containing glycerol dehydrogenase (TM0423) from Thermotoga maritima at 1.5 Å resolution

Adam Godzik, Slawomir K. Grzechnik, Chittibabu Guda, 2002, Proteins.

CRYSTAL STRUCTURE OF AN HIV-1 NEUTRALIZING ANTIBODY 50.1 IN COMPLEX WITH ITS V3 LOOP PEPTIDE ANTIGEN

I. Wilson, R. Stanfield, J. Rini, 1993 .

Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria

I. Wilson, Chi‐Huey Wong, B. Beutler, 2006, Nature Immunology.

Square-Dancing Antibodies

D. Burton, I. Wilson, 2007, Science.

Immunology. Square-dancing antibodies.

D. Burton, I. Wilson, 2007, Science.

Convergent Evolution in Breadth of Two VH6-1-Encoded Influenza Antibody Clonotypes from a Single Donor

Chaim A. Schramm, J. Mascola, I. Wilson, 2020, Cell host & microbe.

Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum

I. Wilson, D. Oyen, C. King, 2020, Nature Communications.

VLR Recognition of TLR5 Expands the Molecular Characterization of Protein Antigen Binding by Non-Ig-based Antibodies.

Brantley R. Herrin, I. Wilson, M. Cooper, 2018, Journal of molecular biology.

Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin.

R. Lerner, I. Wilson, N. Wu, 2017, Cell host & microbe.

Towards optimization of the linker substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies

Steven M. Johnson, I. Wilson, J. Kelly, 2008 .

Covalent display of oligosaccharide arrays in microtiter plates.

D. Burton, I. Wilson, Chi‐Huey Wong, 2004, Journal of the American Chemical Society.

A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection

D. Burton, I. Wilson, D. Nemazee, 2021, bioRxiv.

Structure of the pilus assembly protein TadZ from Eubacterium rectale: implications for polar localization

Mitchell D. Miller, A. Godzik, A. Deacon, 2012, Molecular microbiology.

The Molecular Interaction of CAR and JAML Recruits the Central Cell Signal Transducer PI3K

I. Wilson, P. Verdino, D. Witherden, 2010, Science.

Crystal structure of a gammadelta T cell receptor ligand T22: a truncated MHC-like fold.

Y. Chien, I. Wilson, M. Degano, 2000, Science.

CRYSTAL STRUCTURE ANALYSIS OF THE GAMMA/DELTA T CELL LIGAND T22

Y. Chien, I. Wilson, M. Degano, 2000 .

Differential localization of the mRNA of the M and B isoforms of creatine kinase in myoblasts.

I. Wilson, K. Brindle, A. M. Fulton, 1995, The Biochemical journal.

An analysis of the three-dimensional structure of chicken triose phosphate isomerase.

M. Sternberg, J. Thornton, D. Phillips, 1977, Biochemical Society transactions.

Studies of the histidine residues of triose phosphate isomerase by proton magnetic resonance and x-ray crystallography.

I. Campbell, D. Phillips, I. Wilson, 1976, Journal of molecular biology.

Evidence of antigenic imprinting in sequential Sarbecovirus immunization

I. Wilson, N. Wu, M. Yuan, 2020, bioRxiv.

Structural basis for antibody catalysis of a cationic cyclization reaction.

I. Wilson, K. Houk, A. Heine, 2003, Journal of molecular biology.

Cutting Edge: CD1a Tetramers and Dextramers Identify Human Lipopeptide–Specific T Cells Ex Vivo

I. Wilson, J. Altman, J. Rossjohn, 2013, The Journal of Immunology.

Cofactor-containing antibodies: crystal structure of the original yellow antibody.

R. Lerner, I. Wilson, R. Kyle, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Expression and characterization of a humanized cocaine-binding antibody.

I. Wilson, P. Wirsching, K. Janda, 2003, Biotechnology and bioengineering.

A Blueprint for HIV Vaccine Discovery.

Adam Godzik, Hendrik Streeck, M Juliana McElrath, 2012, Cell host & microbe.

Structural Constraints Det ermine the Glycosylation of HIV-1 Envelope Trimers Graphical

John P. Moore, D. Burton, I. Wilson, 2015 .

Proceedings du 23ème Conseil Solvay de Chimie "New Chemistry and New Opportunities from the Expanding Protein Universe": World Scientific Publishing

Kurt Wüthrich, Donald Hilvert, Ian A. Wilson, 2014 .

Amyloidogenic immunoglobulin light chain kinetic stabilizers comprising a simple urea linker module reveal a novel binding sub-site.

I. Wilson, J. Kelly, G. Morgan, 2022, Bioorganic & medicinal chemistry letters.

Selecting agonists from single cells infected with combinatorial antibody libraries.

R. Lerner, I. Wilson, Jia Xie, 2013, Chemistry & biology.

Influenza H3 and H1 hemagglutinins have different genetic barriers for resistance to broadly neutralizing stem antibodies

R. Lerner, I. Wilson, J. Bloom, 2019, bioRxiv.

Hemagglutinin Receptor Specificity and Structural Analyses of Respiratory Droplet-Transmissible H5N1 Viruses

I. Wilson, Y. Kawaoka, J. Paulson, 2013, Journal of Virology.

Structure of a High-Affinity

Jamie K. Scott, D. Burton, P. Parren, 2007 .

NMR in structural genomics to increase structural coverage of the protein universe

A. Godzik, K. Wüthrich, I. Wilson, 2016, The FEBS journal.

Crystal structure of soluble MD-1 and its interaction with lipid IVa

I. Wilson, G. Han, Sung-il Yoon, 2010, Proceedings of the National Academy of Sciences.

Ebolavirus VP35 Coats the Backbone of Double-Stranded RNA for Interferon Antagonism

I. Wilson, E. Saphire, J. Julien, 2013, Journal of Virology.

Homologous and heterologous serological response to the N-terminal domain of SARS-CoV-2

O. Tsang, I. Wilson, N. Wu, 2021, bioRxiv.

Structure of an MmyB-Like Regulator from C. aurantiacus, Member of a New Transcription Factor Family Linked to Antibiotic Metabolism in Actinomycetes

Mitchell D. Miller, A. Godzik, A. Deacon, 2012, PloS one.

Insights into substrate specificity of geranylgeranyl reductases revealed by the structure of digeranylgeranylglycerophospholipid reductase from Thermoplasma acidophilum , an essential enzyme in the biosynthesis of archaeal membrane lipids

Mitchell D. Miller, Deacon, A. Godzik, 2011 .

The structure of BVU2987 from Bacteroides vulgatus reveals a superfamily of bacterial periplasmic proteins with possible inhibitory function

Mitchell D. Miller, A. Godzik, A. Deacon, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystal structure of a novel archaeal AAA+ ATPase SSO1545 from Sulfolobus solfataricus

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2009, Proteins.

Crystal structure of phosphoribosylformyl‐glycinamidine synthase II, PurS subunit (TM1244) from Thermotoga maritima at 1.90 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2006, Proteins.

Reconstruction of the 1918 Influenza Virus: Unexpected Rewards from the Past

Howard Markel, David Baltimore, Peter C. Doherty, 2012, mBio.

Crystal structure of phospholipase A2 from Indian cobra reveals a trimeric association.

N. Xuong, D. Fremont, I. Wilson, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Crystal structures of apo wild‐type M. jannaschii tyrosyl‐tRNA synthetase (TyrRS) and an engineered TyrRS specific for O‐methyl‐L‐tyrosine

Lei Wang, Peter G Schultz, Yan Zhang, 2005, Protein science : a publication of the Protein Society.

Structural Basis for a Swit ch in Receptor Binding Specificity of Two H 5 N 1 Hemagglutinin Mutants Graphical Abstract Highlights

I. Wilson, R. Sasisekharan, Xueyong Zhu, 2022 .

CTL escape viral variants. I. Generation and molecular characterization.

K. Hahn, D. Jewell, I. Wilson, 1995, Virology.

The hHFE gene of browsing and grazing rhinoceroses: a possible site of adaptation to a low-iron diet.

I. Wilson, J. Speir, E. Beutler, 2001, Blood cells, molecules & diseases.

Recombinant expression of TLR5 proteins by ligand supplementation and a leucine-rich repeat hybrid technique.

I. Wilson, Sung-il Yoon, M. Hong, 2012, Biochemical and biophysical research communications.

Overexpression, crystallization and preliminary X-ray crystallographic analysis of the variable lymphocyte receptor 2913 ectodomain fused with internalin B.

I. Wilson, M. Cooper, Hyun-Jung Kim, 2013, Acta crystallographica. Section F, Structural biology and crystallization communications.

Reactivity-based one-pot synthesis of oligomannoses: defining antigens recognized by 2G12, a broadly neutralizing anti-HIV-1 antibody.

D. Burton, R. Dwek, I. Wilson, 2004, Angewandte Chemie.

The Phosphatidylinositol 3-Kinase/Akt Cassette Regulates Purine Nucleotide Synthesis*

Wei Wang, Ian A Wilson, Gerry R Boss, 2009, Journal of Biological Chemistry.

Reducing V3 Antigenicity and Immunogenicity on Soluble, Native-Like HIV-1 Env SOSIP Trimers

John P. Moore, I. Wilson, D. Montefiori, 2017, Journal of Virology.

Targeted isolation of panels of diverse human protective broadly neutralizing antibodies against SARS-like viruses

D. Burton, I. Wilson, A. Ward, 2021, bioRxiv.

Fluorogen-activating proteins

I. Wilson, M. Bruchez, A. Waggoner, 2011 .

Preliminary X-ray diffraction studies of the transcriptional inhibitory antibody Fab41.4.

I. Wilson, S. Hinrichs, R. Stanfield, 2001, Acta crystallographica. Section D, Biological crystallography.

Protein engineering for crystallization of the GTPase Sar1 that regulates ER vesicle budding.

I. Wilson, W. Balch, Mingdong Huang, 2002, Acta crystallographica. Section D, Biological crystallography.

Crystallization and preliminary structural studies of a chorismate mutase catalytic antibody complexed with a transition state analog

I. Wilson, D. Hilvert, E. Stura, 1994, Proteins.

The Joint Center for Structural Genomics

A. Godzik, A. Deacon, K. Hodgson, 2011 .

Towards miniaturization of a structural genomics pipeline using micro-expression and microcoil NMR

K. Wüthrich, R. Stevens, I. Wilson, 2006, Journal of Structural and Functional Genomics.

10-Formyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid (10-formyl-DDACTHF): a potent cytotoxic agent acting by selective inhibition of human GAR Tfase and the de novo purine biosynthetic pathway.

D. Boger, I. Wilson, S. Benkovic, 2002, Bioorganic & medicinal chemistry.

The Three-dimensional Structure of Surface Antigens from Animal Viruses

I. Wilson, 1986 .

Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model

R. Fuller, R. Wyatt, D. Burton, 2018, Cell reports.

The Second Receptor Binding Site of the Globular Head of the Newcastle Disease Virus Hemagglutinin-Neuraminidase Activates the Stalk of Multiple Paramyxovirus Receptor Binding Proteins To Trigger Fusion

I. Wilson, R. Xu, M. Porotto, 2012, Journal of Virology.

NMR screening and crystal quality of bacterially expressed prokaryotic and eukaryotic proteins in a structural genomics pipeline.

K. Wüthrich, R. Stevens, I. Wilson, 2005, Proceedings of the National Academy of Sciences of the United States of America.

NKT cells sense bacterial infection and recognize bacterial glycolipids

N. Nagarajan, I. Wilson, Chi‐Huey Wong, 2007 .

Cross-reactive Antibody Response between SARS-CoV-2 and SARS-CoV Infections.

J. Peiris, L. Poon, O. Tsang, 2020, Cell reports.

Structural insights into the avian AICAR transformylase mechanism.

I. Wilson, D. Wolan, S. Greasley, 2002, Biochemistry.

Synthesis and Toll-like receptor 4 (TLR4) activity of phosphatidylinositol dimannoside analogues.

I. Wilson, W. Martin, J. Harper, 2011, Journal of medicinal chemistry.

Glycosylation: disease targets and therapy.

D. Burton, R. Dwek, I. Wilson, 2005, Advances in experimental medicine and biology.

A Native-Like SOSIP.664 Trimer Based on an HIV-1 Subtype B env Gene

John P. Moore, D. Burton, I. Wilson, 2015, Journal of Virology.

Kinetic stabilization of an oligomeric protein by a single ligand binding event.

Steven M. Johnson, Ian A Wilson, I. Wilson, 2005, Journal of the American Chemical Society.

Immune Versus Natural Selection : Antibody Aldolases with Enzymic Rates But Broader Scope

A Heine, B List, C. Barbas, 2022 .

Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern

Peter D. Crompton, J. Mascola, I. Wilson, 2021, Science Translational Medicine.

Diverse immunoglobulin gene usage and convergent epitope targeting in neutralizing antibody responses to SARS-CoV-2

D. Burton, I. Wilson, C. Xiao, 2021, Cell Reports.

Single-component, self-assembling, protein nanoparticles presenting the receptor binding domain and stabilized spike as SARS-CoV-2 vaccine candidates

I. Wilson, Jiang Zhu, Linling He, 2021, Science Advances.

An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain

I. Wilson, N. Wu, A. Ward, 2020, Cell Reports.

Cross-neutralization of a SARS-CoV-2 antibody to a functionally conserved site is mediated by avidity

I. Wilson, N. Wu, A. Ward, 2020, bioRxiv.

An alternative binding mode of IGHV3-53 antibodies to the SARS-CoV-2 receptor binding domain

I. Wilson, N. Wu, A. Ward, 2020, bioRxiv.

Dynamics of B-cell repertoires and emergence of cross-reactive responses in COVID-19 patients with different disease severity.

William S. DeWitt, J. Peiris, O. Tsang, 2020, ArXiv.

Structural basis of a shared antibody response to SARS-CoV-2

D. Burton, I. Wilson, N. Wu, 2020, Science.

Structural basis of a public antibody response to SARS-CoV-2

D. Burton, I. Wilson, N. Wu, 2020, bioRxiv.

A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV

Nicholas C. Wu, Xueyong Zhu, Ian A. Wilson, 2020, Science.

Marburg Virus VP35 Can Both Fully Coat the Backbone and Cap the Ends of dsRNA for Interferon Antagonism

I. MacRae, I. Wilson, Y. Kawaoka, 2012, PLoS pathogens.

A fluorogenic aryl fluorosulfate for intraorganellar transthyretin imaging in living cells and in Caenorhabditis elegans.

I. Wilson, J. Kelly, Yvonne S. Eisele, 2015, Journal of the American Chemical Society.

Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue.

I. Wilson, B. Cravatt, Wentao Chen, 2016, Journal of the American Chemical Society.

Antibody Domain Exchange Is an Immunological Solution to Carbohydrate Cluster Recognition

Ping Zhu, Renate Kunert, Pauline M. Rudd, 2003, Science.

Aromatic sulfonyl fluorides covalently kinetically stabilize transthyretin to prevent amyloidogenesis while affording a fluorescent conjugate.

I. Wilson, J. Kelly, E. Powers, 2013, Journal of the American Chemical Society.

Stilbene vinyl sulfonamides as fluorogenic sensors of and traceless covalent kinetic stabilizers of transthyretin that prevent amyloidogenesis.

I. Wilson, J. Kelly, Joseph C. Genereux, 2013, Journal of the American Chemical Society.

Discovery of a potent, nonpolyglutamatable inhibitor of glycinamide ribonucleotide transformylase.

D. Boger, I. Wilson, Lan Xu, 2006, Journal of medicinal chemistry.

Geranylgeranyl switching regulates GDI-Rab GTPase recycling.

R. Gibbs, I. Wilson, W. Balch, 2003, Structure.

Structural analysis of antibody specificity. Detailed comparison of five Fab'-steroid complexes.

I. Wilson, M. Taussig, J. Arevalo, 1994, Journal of molecular biology.

Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method

M. Wigler, R. Lerner, J. Nikawa, 1988, Molecular and cellular biology.

Deeply Inverted Electron-Hole Recombination in a Luminescent Antibody-Stilbene Complex

R. Lerner, P. Schultz, I. Wilson, 2008, Science.

Structural basis for antibody catalysis of a disfavored ring closure reaction.

R. Lerner, I. Wilson, K. Houk, 1999, Biochemistry.

Structure of the first representative of Pfam family PF09410 (DUF2006) reveals a structural signature of the calycin superfamily that suggests a role in lipid metabolism

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

Inhibition of HIV Env binding to cellular receptors by monoclonal antibody 2G12 as probed by Fc-tagged gp120

J. Binley, D. Burton, I. Wilson, 2006, Retrovirology.

Evidence for the production of trioxygen species during antibody-catalyzed chemical modification of antigens

R. Lerner, I. Wilson, K. Janda, 2003, Proceedings of the National Academy of Sciences of the United States of America.

The Broadly Neutralizing Anti-Human Immunodeficiency Virus Type 1 Antibody 2G12 Recognizes a Cluster of α1→2 Mannose Residues on the Outer Face of gp120

H. Katinger, D. Burton, R. Dwek, 2002, Journal of Virology.

Crystal structure of a bacterial cocaine esterase

Richard A. Lerner, Susan J. Rosser, Ian A. Wilson, 2002, Nature Structural Biology.

Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb.

P. A. Peterson, D. Fremont, I. Wilson, 1994, Science.

Partial Enzymatic Deglycosylation Preserves the Structure of Cleaved Recombinant HIV-1 Envelope Glycoprotein Trimers*

John P. Moore, I. Wilson, A. Ward, 2012, The Journal of Biological Chemistry.

Structural Characterization of the Hemagglutinin Receptor Specificity from the 2009 H1N1 Influenza Pandemic

I. Wilson, Corwin M. Nycholat, J. Paulson, 2011, Journal of Virology.

The Unusual Genetics and Biochemistry of Bovine Immunoglobulins.

I. Wilson, R. Stanfield, Vaughn V. Smider, 2018, Advances in immunology.

Crystallization, sequence, and preliminary crystallographic data for an antipeptide Fab 50.1 and peptide complexes with the principal neutralizing determinant of HIV‐1 gpl20

I. Wilson, R. Stanfield, A. Profy, 1992, Proteins.

Exploitation of glycosylation in enveloped virus pathobiology

I. Wilson, M. Crispin, T. Bowden, 2019, Biochimica et Biophysica Acta (BBA) - General Subjects.

A carbohydrate side chain on hemagglutinins of Hong Kong influenza viruses inhibits recognition by a monoclonal antibody.

I. Wilson, J. Skehel, D. Wiley, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Structural Analysis of Papain-Like NlpC/P60 Superfamily Enzymes with a Circularly Permuted Topology Reveals Potential Lipid Binding Sites

Mitchell D. Miller, A. Godzik, A. Deacon, 2011, PloS one.

Identification and structural characterization of heme binding in a novel dye‐decolorizing peroxidase, TyrA

Slawomir K. Grzechnik, Mitchell D. Miller, K. D. Murphy, 2007, Proteins.

Probing the antibody-catalyzed water-oxidation pathway at atomic resolution.

R. Lerner, I. Wilson, Xueyong Zhu, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Molecular basis of crossreactivity and the limits of antibodyantigen complementarity

Ian A. Wilson, Michael J. Taussig, I. Wilson, 1993, Nature.

Combined pseudo-merohedral twinning, non-crystallographic symmetry and pseudo-translation in a monoclinic crystal form of the gammadelta T-cell ligand T10.

Y. Chien, I. Wilson, M. Rudolph, 2004, Acta crystallographica. Section D, Biological crystallography.

Use of multiple anomalous dispersion to phase highly merohedrally twinned crystals of interleukin-1beta.

Ian A Wilson, Todd O Yeates, V. Oseroff, 2003, Acta crystallographica. Section D, Biological crystallography.

Secretory IgA N- and O-Glycans Provide a Link between the Innate and Adaptive Immune Systems*

R. Dwek, I. Wilson, M. Wormald, 2003, Journal of Biological Chemistry.

Structure-based Design, Synthesis, Evaluation, and Crystal Structures of Transition State Analogue Inhibitors of Inosine Monophosphate Cyclohydrolase*

D. Boger, I. Wilson, A. Olson, 2007, Journal of Biological Chemistry.

Synthesis and biological evaluation of N-[4-[5-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-2-(2,2,2-trifluoroacetyl)pentyl]benzoyl]-L-glutamic acid as a potential inhibitor of GAR Tfase and the de novo purine biosynthetic pathway.

D. Boger, I. Wilson, S. Benkovic, 2005, Bioorganic & medicinal chemistry.

Design, synthesis, and biological evaluation of 10-methanesulfonyl-DDACTHF, 10-methanesulfonyl-5-DACTHF, and 10-methylthio-DDACTHF as potent inhibitors of GAR Tfase and the de novo purine biosynthetic pathway.

D. Boger, I. Wilson, S. Benkovic, 2005, Bioorganic & medicinal chemistry.

Design, synthesis, and biological evaluation of simplified alpha-keto heterocycle, trifluoromethyl ketone, and formyl substituted folate analogues as potential inhibitors of GAR transformylase and AICAR transformylase.

D. Boger, I. Wilson, S. Benkovic, 2003, Bioorganic & Medicinal Chemistry.

Design, synthesis and biological evaluation of 10-CF3CO-DDACTHF analogues and derivatives as inhibitors of GAR Tfase and the de novo purine biosynthetic pathway.

D. Boger, I. Wilson, S. Benkovic, 2003, Bioorganic & medicinal chemistry.

T Cell Activation by Lipopeptide Antigens

I. Wilson, D. Zajonc, D. Moody, 2004, Science.

Crystal structure of a non-canonical low-affinity peptide complexed with MHC class I: a new approach for vaccine design.

Vasso Apostolopoulos, Ian A Wilson, Magdalena Plebanski, 2002, Journal of molecular biology.

Recognition of sialylated poly-N-acetyllactosamine chains on N- and O-linked glycans by human and avian influenza A virus hemagglutinins.

Ryan McBride, James C Paulson, Ian A Wilson, 2012, Angewandte Chemie.

Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12.

H. Katinger, D. Burton, I. Wilson, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Soluble human TLR2 ectodomain binds diacylglycerol from microbial lipopeptides and glycolipids

R. Dwek, I. Wilson, M. Wormald, 2015, Innate immunity.

Structural Characterization of Mycobacterial Phosphatidylinositol Mannoside Binding to Mouse CD1d12

Ian A. Wilson, Dirk M. Zajonc, I. Wilson, 2006, The Journal of Immunology.

The structure and role of the carbohydrate moieties of influenza virus haemagglutinin.

I. Wilson, J. Skehel, D. Wiley, 1983, Biochemical Society transactions.

Directed evolution of N-acetylneuraminic acid aldolase to catalyze enantiomeric aldol reactions.

I. Wilson, A. Heine, Chi‐Huey Wong, 2003, Bioorganic & medicinal chemistry.

Open and closed conformations of two SpoIIAA-like proteins (YP_749275.1 and YP_001095227.1) provide insights into membrane association and ligand binding

Mitchell D. Miller, A. Godzik, A. Deacon, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structure of avian AICAR transformylase with a multisubstrate adduct inhibitor beta-DADF identifies the folate binding site.

I. Wilson, S. Benkovic, D. Wolan, 2003, Biochemistry.

Structural Insights into the Avian AICAR Transformylase Mechanism

I. Wilson, D. Wolan, S. Greasley, 2002 .

Crystal structure of a bifunctional transformylase and cyclohydrolase enzyme in purine biosynthesis

I. Wilson, S. Benkovic, S. Greasley, 2001, Nature Structural Biology.

Biological and structural evaluation of 10R- and 10S-methylthio-DDACTHF reveals a new role for sulfur in inhibition of glycinamide ribonucleotide transformylase.

D. Boger, I. Wilson, S. Connelly, 2013, Biochemistry.

10-(2-benzoxazolcarbonyl)-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid: a potential inhibitor of GAR transformylase and AICAR transformylase.

D. Boger, I. Wilson, S. Benkovic, 2003, Bioorganic & medicinal chemistry.

Rational design, synthesis, evaluation, and crystal structure of a potent inhibitor of human GAR Tfase: 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid.

Stephen J Benkovic, Yan Zhang, Ali Tavassoli, 2003, Biochemistry.

New insights into inhibitor design from the crystal structure and NMR studies of Escherichia coli GAR transformylase in complex with beta-GAR and 10-formyl-5,8,10-trideazafolic acid.

D. Boger, I. Wilson, S. Benkovic, 1999, Biochemistry.

Towards structure-based drug design: crystal structure of a multisubstrate adduct complex of glycinamide ribonucleotide transformylase at 1.96 A resolution.

I. Wilson, S. Benkovic, C. Klein, 1995, Journal of molecular biology.

Crystal structure of glycinamide ribonucleotide transformylase from Escherichia coli at 3.0 A resolution. A target enzyme for chemotherapy.

I. Wilson, S. Benkovic, James Inglese, 1992, Journal of molecular biology.

Preliminary crystallographic investigations of glycinamide ribonucleotide transformylase.

I. Wilson, S. Benkovic, James Inglese, 1989, The Journal of biological chemistry.

Synthesis and biological evaluation of alpha- and gamma-carboxamide derivatives of 10-CF3CO-DDACTHF.

D. Boger, I. Wilson, S. Benkovic, 2005, Bioorganic & medicinal chemistry.

Asymmetric synthesis of inhibitors of glycinamide ribonucleotide transformylase.

D. Boger, I. Wilson, S. Connelly, 2008, Journal of medicinal chemistry.

The structure of the first representative of Pfam family PF06475 reveals a new fold with possible involvement in glycolipid metabolism

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

Printed covalent glycan array for ligand profiling of diverse glycan binding proteins.

Chi-Huey Wong, James C Paulson, Ian A Wilson, 2004, Proceedings of the National Academy of Sciences of the United States of America.

The origin of enantioselectivity in aldolase antibodies: crystal structure, site-directed mutagenesis, and computational analysis.

R. Fuller, R. Lerner, I. Wilson, 2004, Journal of molecular biology.

Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation.

I. Wilson, O. Livnah, E. Stura, 1999, Science.

Erythropoietin receptor activation by a ligand-induced conformation change.

I. Wilson, S. Michnick, I. Remy, 1999, Science.

Structure of a virulence regulatory factor CvfB reveals a novel winged helix RNA binding module.

Mitchell D. Miller, A. Godzik, A. Deacon, 2010, Structure.

Design of natural killer T cell activators: structure and function of a microbial glycosphingolipid bound to mouse CD1d.

I. Wilson, Chi‐Huey Wong, D. Zajonc, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands.

Chi-Huey Wong, Ian A Wilson, I. Wilson, 2009, Journal of molecular biology.

Anatomy of CD1–lipid antigen complexes

I. Wilson, D. Zajonc, D. Moody, 2005, Nature Reviews Immunology.

Crystal structure of CD1a in complex with a sulfatide self antigen at a resolution of 2.15 Å

I. Wilson, D. Zajonc, M. Elsliger, 2003, Nature Immunology.

Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity

Chi-Huey Wong, Ian A. Wilson, Dirk M. Zajonc, 2005, The Journal of experimental medicine.

Crystal Structure of Mouse CD1d Bound to the Self Ligand Phosphatidylcholine: A Molecular Basis for NKT Cell Activation12

I. Wilson, M. Degano, M. Crispin, 2005, The Journal of Immunology.

Crystal structure of mouse CD1: An MHC-like fold with a large hydrophobic binding groove.

P. A. Peterson, I. Wilson, E. Stura, 1997, Science.

Shared and Unique Determinants of the Erythropoietin (EPO) Receptor Are Important for Binding EPO and EPO Mimetic Peptide*

I. Wilson, R. Thurmond, M. Goldsmith, 1999, The Journal of Biological Chemistry.

HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage

Ben Murrell, Terri Wrin, Sergei L. Kosakovsky Pond, 2017, Immunity.

Crystal structures of mouse CD1d-iGb3 complex and its cognate Valpha14 T cell receptor suggest a model for dual recognition of foreign and self glycolipids.

I. Wilson, P. Savage, D. Zajonc, 2008, Journal of molecular biology.

Molecular mechanism of lipopeptide presentation by CD1a.

R. Dwek, I. Wilson, D. Zajonc, 2005, Immunity.

Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques

Yana Safonova, D. Irvine, D. Burton, 2021, bioRxiv.

Recognition of the SARS-CoV-2 receptor binding domain by neutralizing antibodies

I. Wilson, N. Wu, M. Yuan, 2020, Biochemical and Biophysical Research Communications.

Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model

D. Burton, I. Wilson, B. Briney, 2020, Science.

Crystallization and preliminary crystallographic investigations of avian 5-aminoimidazole-4-carboxamide ribonucleotide transformylase-inosine monophosphate cyclohydrolase expressed in Escherichia coli.

I. Wilson, V. M. Reyes, E. Stura, 2000, Acta crystallographica. Section D, Biological crystallography.

A small-molecule fusion inhibitor of influenza virus is orally active in mice

I. Wilson, Divita Garg, D. Roymans, 2019, Science.

Structure of LP2179, the first representative of Pfam family PF08866, suggests a new fold with a role in amino-acid metabolism

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystallization and preliminary crystallographic data for an antiprogesterone monoclonal antibody Fab' and steroid-Fab' complexes.

I. Wilson, E. Stura, A. Feinstein, 1987, Journal of molecular biology.

Molecular Features of the Broadly Neutralizing Immunoglobulin G1 b12 Required for Recognition of Human Immunodeficiency Virus Type 1 gp120

Jamie K. Scott, D. Burton, P. Parren, 2003, Journal of Virology.

Crystal structures of two subtype N10 neuraminidase-like proteins from bat influenza A viruses reveal a diverged putative active site

I. Wilson, J. Paulson, S. Tong, 2012, Proceedings of the National Academy of Sciences.

An unusual dimeric structure and assembly for TLR4 regulator RP105–MD-1

I. Wilson, Sung-il Yoon, M. Hong, 2011, Nature Structural &Molecular Biology.

The CD100 receptor interacts with its plexin B2 ligand to regulate epidermal γδ T cell function.

I. Wilson, H. Kikutani, W. Fischer, 2012, Immunity.

A General Method for Insertion of Functional Proteins within Proteins via Combinatorial Selection of Permissive Junctions.

R. Lerner, I. Wilson, J. Friedman, 2015, Chemistry & biology.

The Chimpanzee SIV Envelope Trimer: Structure and Deployment as an HIV Vaccine Template

B. Haynes, D. Burton, I. Wilson, 2019, Cell reports.

Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor-binding head domains

I. Wilson, J. Pallesen, J. Crowe, 2018, bioRxiv.

Chimpanzee SIV Envelope trimer: structure and deployment as an HIV vaccine template

B. Haynes, D. Burton, I. Wilson, 2018, bioRxiv.

A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure

D. Burton, I. Wilson, N. Wu, 2017, Immunity.

Crystal structure of the Drosophila peptidoglycan recognition protein (PGRP)-SA at 1.56 A resolution.

I. Wilson, L. Teyton, J. Reiser, 2004, Journal of molecular biology.

T cells control the generation of nanomolar-affinity anti-glycan antibodies

I. Wilson, P. Savage, S. Crotty, 2017, The Journal of clinical investigation.

Crystal structure of MHC class II I-Ab in complex with a human CLIP peptide: prediction of an I-Ab peptide-binding motif.

Ian A Wilson, A. Rudensky, I. Wilson, 2003, Journal of molecular biology.

Another Twist to MHC-Peptide Recognition

I. Wilson, 1996, Science.

Protein-peptide interactions.

R L Stanfield, I. Wilson, R. Stanfield, 1995, Current opinion in structural biology.

Antibody-antigen interactions: new structures and new conformational changes.

R L Stanfield, I. Wilson, R. Stanfield, 1994, Current opinion in structural biology.

Protein biophysical properties that correlate with crystallization success in Thermotoga maritima: maximum clustering strategy for structural genomics.

Rebecca Page, Ian A Wilson, Raymond C Stevens, 2004, Journal of molecular biology.

Structural Insights into the Lipid A Transport Pathway in MsbA.

E. Tajkhorshid, I. Wilson, R. Stanfield, 2019, Structure.

Structural Basis of TLR5-Flagellin Recognition and Signaling

I. Wilson, A. Osterman, A. Gudkov, 2012, Science.

Structural basis of steroid hormone perception by the receptor kinase BRI1

I. Wilson, J. Noel, J. Chory, 2011, Nature.

Crystal Structure of Human Toll-Like Receptor 3 (TLR3) Ectodomain

I. Wilson, J. Choe, M. Kelker, 2005, Science.

Crystal Structure of a Shark Single-Domain Antibody V Region in Complex with Lysozyme

I. Wilson, M. Flajnik, R. Stanfield, 2004, Science.

Flagellin as Carrier and Adjuvant in Cocaine Vaccine Development

I. Wilson, K. Janda, Jennifer L Choi, 2014, Molecular pharmaceutics.

Crystal Structure of the Human N-Myc Downstream-regulated Gene 2 Protein Provides Insight into Its Role as a Tumor Suppressor

A. Deacon, Cheol‐Hee Kim, I. Wilson, 2011, The Journal of Biological Chemistry.

Structure and functional characterization of a bile acid 7α dehydratase BaiE in secondary bile acid synthesis

Mitchell D. Miller, I. Wilson, S. Lesley, 2016, Proteins.

Structure and functional characterization of a bile acid 7α dehydratase BaiE in secondary bile acid synthesis

Mitchell D. Miller, I. Wilson, S. Lesley, 2016, Proteins: Structure, Function, and Bioinformatics.

Crystal structure of uronate isomerase (TM0064) from Thermotoga maritima at 2.85 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2003, Proteins.

A structural analysis of M protein in coronavirus assembly and morphology

I. Wilson, B. Neuman, M. Buchmeier, 2010, Journal of Structural Biology.

Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization

D. Burton, I. Wilson, H. Turner, 2018, Immunity.

Robust de novo design of protein binding proteins from target structural information alone

D. Baker, K. Garcia, I. Wilson, 2021, bioRxiv.

An MPER antibody neutralizes HIV-1 using germline features shared among donors

D. Burton, I. Wilson, A. Ward, 2019, Nature Communications.

Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design

Andreia M. Serra, D. Burton, I. Wilson, 2017, PLoS pathogens.

Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.

I. Wilson, R. Stanfield, A. Irimia, 2016, Immunity.

Cross-reactive Antibody Response between SARS-CoV-2 and SARS-CoV Infections.

J. Peiris, L. Poon, O. Tsang, 2020, Cell reports.

Molecular insights into γδ T cell costimulation by an anti-JAML antibody.

I. Wilson, A. Schiefner, A. Corper, 2011, Structure.

Identification of a 13 amino acid peptide mimetic of erythropoietin and description of amino acids critical for the mimetic activity of EMP1.

L S Mulcahy, I. Wilson, O. Livnah, 1998, Biochemistry.

Structural and Functional Characterizations of SsgB, a Conserved Activator of Developmental Cell Division in Morphologically Complex Actinomycetes*

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2009, The Journal of Biological Chemistry.

The structure of Jann_2411 (DUF1470) from Jannaschia sp. at 1.45 Å resolution reveals a new fold (the ABATE domain) and suggests its possible role as a transcription regulator

Slawomir K. Grzechnik, Mitchell D. Miller, K. D. Murphy, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

CHAPTER 6 – Antibody–Antigen Recognition and Conformational Changes

I. Wilson, R. Stanfield, 2003 .

Structure of anti-peptide antibody complexes.

I. Wilson, R. Stanfield, J. Ghiara, 1994, Research in immunology.

Strategies in the crystallization of glycoproteins and protein complexes

G. Nemerow, I. Wilson, E. Stura, 1992 .

Generation of protein-reactive antibodies by short peptides is an event of high frequency: implications for the structural basis of immune recognition.

R. Lerner, I. Wilson, R. Houghten, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Anti-peptide antibodies detect steps in a protein conformational change: low-pH activation of the influenza virus hemagglutinin

I. Wilson, J. White, J. White, 1987, The Journal of cell biology.

Antibody responses to viral infections: a structural perspective across three different enveloped viruses

I. Wilson, C. D. Murin, A. Ward, 2019, Nature Microbiology.

Emerging principles for T cell receptor recognition of antigen in cellular immunity.

K. Garcia, I. Wilson, M. Degano, 1999, Reviews in immunogenetics.

Closing and Opening Holes in the Glycan Shield of HIV-1 Envelope Glycoprotein SOSIP Trimers Can Redirect the Neutralizing Antibody Response to the Newly Unmasked Epitopes

Andrew B. Ward, Ian A. Wilson, David C. Montefiori, 2018, Journal of Virology.

Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits

John P. Moore, D. Burton, I. Wilson, 2014, Retrovirology.

Structure and functional characterization of the RNA-binding element of the NLRX1 innate immune modulator.

I. Wilson, Sung-il Yoon, M. Hong, 2012, Immunity.

Serological assays for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), March 2020

Malik Peiris, Ian A Wilson, Kathy Leung, 2020, Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin.

Antigen Recognition by Variable Lymphocyte Receptors

Ian A. Wilson, Brantley R. Herrin, I. Wilson, 2008, Science.

Antibody vs. HIV in a clash of evolutionary titans.

Robyn L Stanfield, Ian A Wilson, Dennis R Burton, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Thermal responses reflect protein turnover in Mytilus edulis L.

I. Wilson, B. Bayne, A. Hawkins, 1987 .

XtalPred: a web server for prediction of protein crystallizability

Leszek Rychlewski, Adam Godzik, Lukasz Jaroszewski, 2007, Bioinform..

A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface

I. Wilson, S. Kent, J. Crowe, 2019, Cell.

Fleishman Region of Influenza Hemagglutinin Computational Design of Proteins Targeting the Conserved Stem

Timothy A. Whitehead, I. Wilson, S. Fleishman, 2011 .

A dynamic switch in inactive p38γ leads to an excited state on pathway to an active kinase.

H. Dyson, P. Wright, I. Wilson, 2019, Biochemistry.

A peptide inhibitor of HIV‐1 neutralizing antibody 2G12 is not a structural mimic of the natural carbohydrate epitope on gp120

H. Katinger, D. Burton, I. Wilson, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

A structural basis for the regulatory inactivation of DnaA.

Mitchell D. Miller, A. Godzik, A. Deacon, 2009, Journal of molecular biology.

Supplemental Data Structural Basis of Murein Peptide Specificity of a γ-D-Glutamyl-L-Diamino Acid Endopeptidase

Linda, Slawomir K. Grzechnik, Mitchell D. Miller, 2009 .

The Joint Center for Structural Genomics: exploration of the human gut microbiome

I. Wilson, 2011, Genome Biology.

Structural basis of influenza virus fusion inhibition by the antiviral drug Arbidol

I. Wilson, R. Kadam, 2016, Proceedings of the National Academy of Sciences.

Alphabeta T cell receptor interactions with syngeneic and allogeneic ligands: affinity measurements and crystallization.

L R Pease, P. A. Peterson, K. Garcia, 1997, Proceedings of the National Academy of Sciences of the United States of America.

A Single Amino Acid Substitution in 1918 Influenza Virus Hemagglutinin Changes Receptor Binding Specificity

Ian A. Wilson, James Stevens, Jeffery K. Taubenberger, 2005, Journal of Virology.

50 Years of structural immunology

I. Wilson, R. Stanfield, 2021, Journal of Biological Chemistry.

Crystal structure of an isolated V(alpha) domain of the 2C T-cell receptor.

I. Wilson, M. Rudolph, L. Teyton, 2001, Journal of molecular biology.

The crystal structures of K(bm1) and K(bm8) reveal that subtle changes in the peptide environment impact thermostability and alloreactivity.

M R Jackson, M. Jackson, P. A. Peterson, 2001, Immunity.

Structural basis of 2C TCR allorecognition of H-2Ld peptide complexes.

P. A. Peterson, K. Garcia, I. Wilson, 1998, Immunity.

Outcome of a workshop on applications of protein models in biomedical research.

Roland L Dunbrack, Roland L. Dunbrack, Andrej Sali, 2009, Structure.

Structure-based optimization and synthesis of antiviral drug Arbidol analogues with significantly improved affinity to influenza hemagglutinin.

I. Wilson, D. Wolan, N. Wu, 2017, Bioorganic & medicinal chemistry letters.

Structural Biology of Influenza Hemagglutinin: An Amaranthine Adventure

I. Wilson, N. Wu, 2020, Viruses.

Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms

R. Lerner, I. Wilson, Y. Wan, 2021, Nature Communications.

A Perspective on the Structural and Functional Constraints for Immune Evasion: Insights from Influenza Virus.

I. Wilson, N. Wu, 2017, Journal of molecular biology.

Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin.

R. Lerner, I. Wilson, N. Wu, 2017, Cell host & microbe.

Functional Balance of the Hemagglutinin and Neuraminidase Activities Accompanies the Emergence of the 2009 H1N1 Influenza Pandemic

I. Wilson, Corwin M. Nycholat, J. Paulson, 2012, Journal of Virology.

Influenza Virus Neuraminidases with Reduced Enzymatic Activity That Avidly Bind Sialic Acid Receptors

I. Wilson, Corwin M. Nycholat, J. Paulson, 2012, Journal of Virology.

Single-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccines

I. Wilson, R. Stanfield, Jiang Zhu, 2020, Nature Communications.

Structure and Immune Recognition of the HIV Glycan Shield.

Ian A Wilson, I. Wilson, A. Ward, 2018, Annual review of biophysics.

Crystal structure of the HIV neutralizing antibody 2G12 in complex with a bacterial oligosaccharide analog of mammalian oligomannose.

I. Wilson, R. Stanfield, C. de Castro, 2014, Glycobiology.

A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike

Lu Lu, Wenjie Tan, Qian Wang, 2019, Science Advances.

Genetic and structural insights into broad neutralization of hepatitis C virus by human VH1-69 antibodies

J. Bukh, I. Wilson, G. Lauer, 2019, Science Advances.

A human-infecting H10N8 influenza virus retains a strong preference for avian-type receptors.

Ryan McBride, Heng Zhang, Xueyong Zhu, 2015, Cell host & microbe.

Single-component, self-assembling, protein nanoparticles presenting the receptor binding domain and stabilized spike as SARS-CoV-2 vaccine candidates

I. Wilson, Jiang Zhu, Linling He, 2020, bioRxiv.

Massively parallel de novo protein design for targeted therapeutics

Lu Zhang, Xuhui Huang, David Baker, 2017, Nature.

Vulnerabilities in coronavirus glycan shields despite extensive glycosylation

Zachary T. Berndsen, Andrew B. Ward, Jason S. McLellan, 2020, Nature Communications.

Functional Mimicry of a Protein Hormone by a Peptide Agonist: The EPO Receptor Complex at 2.8 Å

Enrico A. Stura, Ian A. Wilson, William J. Dower, 1996, Science.

Structure of the Wilms tumor suppressor protein zinc finger domain bound to DNA.

H. Dyson, P. Wright, I. Wilson, 2007, Journal of molecular biology.

A VH1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite

I. Wilson, Jiang Zhu, K. Hong, 2020, Science Advances.

Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor.

J. Mascola, R. Wyatt, I. Wilson, 2016, Immunity.

Three mutations switch H7N9 influenza to human-type receptor specificity

Ryan McBride, Robert J Woods, Xueyong Zhu, 2017, PLoS pathogens.

Self-assembling nanoparticles presenting receptor binding domain and stabilized spike as next-generation COVID-19 vaccines

I. Wilson, Jiang Zhu, Linling He, 2020, bioRxiv.

Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike

John P. Moore, D. Burton, I. Wilson, 2015, Nature Communications.

Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens

John P. Moore, I. Wilson, A. Ward, 2015, Proceedings of the National Academy of Sciences.

Structural Characterization of Cleaved, Soluble HIV-1 Envelope Glycoprotein Trimers

John P. Moore, I. Wilson, A. Ward, 2013, Journal of Virology.

Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans

Ryan McBride, Robyn L. Stanfield, Andrew B. Ward, 2013, PLoS pathogens.

HIV-1 SOSIP envelope glycoprotein 2

John P. Moore, I. Wilson, A. Ward, 2013 .

, Albert Trimers Soluble HIV-1 Envelope Glycoprotein Structural Characterization of Cleaved

John P. Moore, I. Wilson, J. Julien, 2013 .

Highly Conserved Protective Epitopes on Influenza B Viruses

N. S. Laursen, L. Poon, I. Wilson, 2012, Science.

A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

Yan Liu, William R. Schief, Ryan McBride, 2011, Science.

Structural characterization of viral epitopes recognized by broadly cross-reactive antibodies.

I. Wilson, Peter S. Lee, 2015, Current topics in microbiology and immunology.

Characterization of a Broadly Neutralizing Monoclonal Antibody That Targets the Fusion Domain of Group 2 Influenza A Virus Hemagglutinin

I. Wilson, A. Ward, Paul E. Leon, 2014, Journal of Virology.

Integrative Structural Biology

Andrej Sali, Ian A. Wilson, Andrew B. Ward, 2013, Science.

Crystal structure of Sar1-GDP at 1.7 Å resolution and the role of the NH2 terminus in ER export

I. Wilson, W. Balch, Mingdong Huang, 2001, The Journal of cell biology.

Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies

David Nemazee, Joseph G. Jardine, Oleksandr Kalyuzhniy, 2016, Cell.

Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design

D. Burton, I. Wilson, W. Schief, 2016, PLoS pathogens.

Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120

Yan Liu, Ryan McBride, Robyn L. Stanfield, 2013, Nature Structural &Molecular Biology.

HIV-1 and influenza antibodies: seeing antigens in new ways

I. Wilson, P. Kwong, 2009, Nature Immunology.

A Glycoconjugate Antigen Based on the Recognition Motif of a Broadly Neutralizing Human Immunodeficiency Virus Antibody, 2G12, Is Immunogenic but Elicits Antibodies Unable To Bind to the Self Glycans of gp120

D. Burton, R. Dwek, I. Wilson, 2008, Journal of Virology.

An Affinity-Enhanced Neutralizing Antibody against the Membrane-Proximal External Region of Human Immunodeficiency Virus Type 1 gp41 Recognizes an Epitope between Those of 2F5 and 4E10

J. Binley, D. Burton, I. Wilson, 2007, Journal of Virology.

Genetic and Phenotypic Analyses of Human Immunodeficiency Virus Type 1 Escape from a Small-Molecule CCR5 Inhibitor

Robyn L Stanfield, Ian A Wilson, B. Korber, 2004, Journal of Virology.

Broadly Neutralizing Antibodies Present New Prospects to Counter Highly Antigenically Diverse Viruses

D. Burton, I. Wilson, P. Poignard, 2012, Science.

Stabilization of the gp120 V3 loop through hydrophobic interactions reduces the immunodominant V3-directed non-neutralizing response to HIV-1 envelope trimers

John P. Moore, I. Wilson, D. Montefiori, 2017, The Journal of Biological Chemistry.

Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes

John P. Moore, B. Berkhout, I. Wilson, 2015, Cell.

D-101 HIV-1 neutralizing antibodies induced by native-like envelope trimers

G. Debnath, John P. Moore, D. Burton, 2016 .

A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection

D. Burton, I. Wilson, N. Wu, 2021, Cell Host & Microbe.

A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection

I. Wilson, N. Wu, D. Nemazee, 2021, bioRxiv.

New approaches to vaccination

I. Wilson, G. Nabel, D. Ekiert, 2013 .

Structure of Hepatitis C Virus Envelope Glycoprotein E2 Antigenic Site 412 to 423 in Complex with Antibody AP33

I. Wilson, R. Stanfield, Travis Nieusma, 2012, Journal of Virology.

Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein

Weston B Struwe, Louise Royle, Ian A Wilson, 2016, Cell reports.

A pH-dependent stabilization of an active site loop observed from low and high pH crystal structures of mutant monomeric glycinamide ribonucleotide transformylase at 1.8 to 1.9 A.

J. H. Shim, I. Wilson, S. Benkovic, 1998, Journal of molecular biology.

NMR structure of the conserved hypothetical protein TM0487 from Thermotoga maritima: Implications for 216 homologous DUF59 proteins

K. Wüthrich, I. Wilson, M. Almeida, 2005, Protein science : a publication of the Protein Society.

Crystal structure of an orphan protein (TM0875) from Thermotoga maritima at 2.00‐Å resolution reveals a new fold

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins.

Crystal structure of a glycerophosphodiester phosphodiesterase (GDPD) from Thermotoga maritima (TM1621) at 1.60 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins.

Structure of a high-affinity "mimotope" peptide bound to HIV-1-neutralizing antibody b12 explains its inability to elicit gp120 cross-reactive antibodies.

Jamie K. Scott, Erica Ollmann Saphire, Ian A Wilson, 2007, Journal of molecular biology.

The structure, organization, activation and plasticity of the erythropoietin receptor.

I. Wilson, L. Jolliffe, 1999, Current opinion in structural biology.

Crystal structure of the post‐fusion core of the Human coronavirus 229E spike protein at 1.86 Å resolution

I. Wilson, Bei Yang, J. Xiang, 2018, Acta crystallographica. Section D, Structural biology.

AG10 inhibits amyloidogenesis and cellular toxicity of the familial amyloid cardiomyopathy-associated V122I transthyretin

I. Graef, I. Wilson, M. Liedtke, 2013, Proceedings of the National Academy of Sciences.

A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine

I. Wilson, N. Wu, Seth J. Zost, 2017, PLoS pathogens.

A functional hot spot for antigen recognition in a superagonist TCR/MHC complex.

K. Garcia, V. Apostolopoulos, I. Wilson, 2000, Immunity.

Crystal structures of two novel dye‐decolorizing peroxidases reveal a β‐barrel fold with a conserved heme‐binding motif

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2007, Proteins.

Crystal structure of an aspartate aminotransferase (TM1255) from Thermotoga maritima at 1.90 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins.

Kinetic stabilization of the native state by protein engineering: implications for inhibition of transthyretin amyloidogenesis.

I. Wilson, J. Kelly, R. L. Wiseman, 2005, Journal of molecular biology.

Adaptive mutations alter antibody structure and dynamics during affinity maturation.

I. Wilson, M. Oda, R. Stanfield, 2015, Biochemistry.

Somatic hypermutation maintains antibody thermodynamic stability during affinity maturation

Feng Wang, Peter G Schultz, Xueyong Zhu, 2013, Proceedings of the National Academy of Sciences.

Molecular Recognition of Lipid Antigens by T Cell Receptors

Ian A. Wilson, Michael B. Brenner, Steven A. Porcelli, 1999, The Journal of experimental medicine.

THE HIV VACCINE PROBLEM : WHY HAVE PAST APPROACHES TO DEVELOP AN HIV VACCINE FAILED ?

Walker, A. Godzik, B. Walker, 2022 .

Influenza Human Monoclonal Antibody 1F1 Interacts with Three Major Antigenic Sites and Residues Mediating Human Receptor Specificity in H1N1 Viruses

James E. Crowe, Damian C. Ekiert, Ian A. Wilson, 2012, PLoS pathogens.

The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.G9 complex.

T S Edgington, W Ruf, I. Wilson, 1998, Journal of molecular biology.

CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes

P. A. Peterson, K. Garcia, I. Wilson, 1996, Nature.

HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies

Dong Soo Yun, Daniel W. Kulp, D. Irvine, 2016, Immunity.

Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers.

Wayne C Koff, Chung-Yi Wu, Chi-Huey Wong, 2014, Immunity.

New Design of MHC Class II Tetramers to Accommodate Fundamental Principles of Antigen Presentation1

K. Garcia, I. Wilson, J. Altman, 2009, The Journal of Immunology.

Crystal structure of the TCR co-receptor CD8alphaalpha in complex with monoclonal antibody YTS 105.18 Fab fragment at 2.88 A resolution.

R. Dwek, I. Wilson, P. Rudd, 2006, Journal of molecular biology.

T Cell Receptors are Structures Capable of Initiating Signaling in the Absence of Large Conformational Rearrangements*

I. Wilson, D. Shore, Xueyong Zhu, 2012, The Journal of Biological Chemistry.

T Cell Receptor/pMHC Complexes

I. Wilson, M. Rudolph, R. Stanfield, 2010 .

Supine Orientation of a Murine MHC Class I Molecule on the Membrane Bilayer

Ian A Wilson, I. Wilson, J. Luz, 2004, Current Biology.

CHAPTER 11 – T-Cell Receptor/pMHC Complexes

I. Wilson, M. Rudolph, 2003 .

Structural Comparison of Allogeneic and Syngeneic T Cell Receptor–Peptide-Major Histocompatibility Complex Complexes

Vasso Apostolopoulos, Markus G. Rudolph, Mingdong Huang, 2002, The Journal of experimental medicine.

Unraveling the mysteries of γδ T cell recognition

I. Wilson, R. Stanfield, 2001, Nature Immunology.

Two different, highly exposed, bulged structures for an unusually long peptide bound to rat MHC class I RT1-Aa.

G W Butcher, I. Wilson, J. Speir, 2001, Immunity.

Crystal Structure of a γδ T Cell Receptor Ligand T22: A Truncated MHC-Like Fold

Y. Chien, I. Wilson, M. Degano, 2000 .

Class-Conscious TCR?

I. Wilson, 1999, Science.

Alanine Scanning Mutagenesis of an αβ T Cell Receptor: Mapping the Energy of Antigen Recognition

K. Garcia, I. Wilson, D. Kranz, 1998 .

T-cell receptor structure and TCR complexes.

K. Garcia, I. Wilson, I. Wilson, 1997, Current opinion in structural biology.

Structural analysis of MHC class I molecules with bound peptide antigens.

D. Fremont, I. Wilson, I A Wilson, 1993, Seminars in immunology.

Structure-based design of a protein immunogen that displays an HIV-1 gp41 neutralizing epitope.

I. Wilson, J. Julien, R. Stanfield, 2011, Journal of molecular biology.

Structure of Human Toll-like Receptor 3 (TLR3) Ligand- binding Domain

I. Wilson, J. Choe, M. Kelker, 2005 .

A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA

I. Wilson, S. Kent, J. Crowe, 2018, Nature Communications.

Crystal structures of three representatives of a new Pfam family PF14869 (DUF4488) suggest they function in sugar binding/uptake

Mitchell D. Miller, A. Godzik, A. Deacon, 2014, Protein science : a publication of the Protein Society.

Structure of BT_3984, a member of the SusD/RagB family of nutrient-binding molecules

Mitchell D. Miller, A. Godzik, A. Deacon, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

The structure of KPN03535 (gi|152972051), a novel putative lipoprotein from Klebsiella pneumoniae, reveals an OB-fold

Mitchell D. Miller, A. Godzik, A. Deacon, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

The challenge of protein structure determination—lessons from structural genomics

Leszek Rychlewski, Adam Godzik, Ana P. C. Rodrigues, 2007, Protein science : a publication of the Protein Society.

Dynamics of B cell repertoires and emergence of cross-reactive responses in patients with different severities of COVID-19

William S. DeWitt, J. Peiris, I. Wilson, 2021, Cell Reports.

Dynamics of B-cell repertoires and emergence of cross-reactive responses in COVID-19 patients with different disease severity

William S. DeWitt, J. Peiris, O. Tsang, 2020, medRxiv.

Crystal Structure and Activity Studies of the C11 Cysteine Peptidase from Parabacteroides merdae in the Human Gut Microbiome*

A. Godzik, A. Deacon, I. Wilson, 2016, The Journal of Biological Chemistry.

Insights into Substrate Specificity of NlpC/P60 Cell Wall Hydrolases Containing Bacterial SH3 Domains

A. Godzik, A. Deacon, I. Wilson, 2015, mBio.

Structure-guided functional characterization of DUF1460 reveals a highly specific NlpC/P60 amidase family.

A. Godzik, A. Deacon, I. Wilson, 2014, Structure.

The structure of SSO2064, the first representative of Pfam family PF01796, reveals a novel two-domain zinc-ribbon OB-fold architecture with a potential acyl-CoA-binding role

Mitchell D. Miller, A. Godzik, A. Deacon, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation

John P. Moore, I. Wilson, Helen J Kim, 2013, Proceedings of the National Academy of Sciences.

Innovations in structure-based antigen design and immune monitoring for next generation vaccines

Ian A Wilson, Andrew B Ward, I. Wilson, 2020, Current Opinion in Immunology.

Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso

H. Dyson, P. Wright, I. Wilson, 2012, Proceedings of the National Academy of Sciences.

Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide

John P. Moore, I. Wilson, A. Ward, 2019, Nature Communications.

Oligomannose Glycopeptide Conjugates Elicit Antibodies Targeting the Glycan Core Rather than Its Extremities

I. Wilson, D. Montefiori, R. Stanfield, 2019, ACS central science.

Comprehensive Antigenic Map of a Cleaved Soluble HIV-1 Envelope Trimer

John P. Moore, D. Burton, I. Wilson, 2015, PLoS pathogens.

Insights into the trimeric HIV-1 envelope glycoprotein structure.

I. Wilson, A. Ward, 2015, Trends in biochemical sciences.

Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers.

James C Paulson, Pascal Poignard, Ian A Wilson, 2014, Immunity.

Neutralizing Antibodies Induced by First-Generation gp41-Stabilized HIV-1 Envelope Trimers and Nanoparticles

I. Wilson, A. Ward, Jiang Zhu, 2020, bioRxiv.

A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses

Daniel W. Kulp, Xiaozhen Hu, D. Burton, 2019, Science.

Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo

L. Stamatatos, John P. Moore, M. V. van Breemen, 2017, The Journal of experimental medicine.

Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch.

Ben Murrell, Terri Wrin, Sergei L. Kosakovsky Pond, 2016, Immunity.

Two Classes of Broadly Neutralizing Antibodies within a Single Lineage Directed to the High-Mannose Patch of HIV Envelope

D. Burton, I. Wilson, Uri Laserson, 2014, Journal of Virology.

Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis.

I. Wilson, A. Olson, Zhengfan Jiang, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Erythropoietin Receptor as a Paradigm for Cytokine Signaling

I. Wilson, Minmin Yu, D. Stauber, 2010 .

CHAPTER 44 – Erythropoietin Receptor as a Paradigm for Cytokine Signaling

I. Wilson, Minmin Yu, D. Stauber, 2003 .

Peptide mimetics of erythropoietin are powerful probes of receptor activation mechanisms

I. Wilson, O. Livnah, E. Stura, 2002 .

A peptide mimetic of erythropoietin: Critical residues and description of a minimal functional epitope

I. Wilson, O. Livnah, W. Dower, 2002 .

Crystal structure of viral macrophage inflammatory protein I encoded by Kaposi's sarcoma-associated herpesvirus at 1.7A.

I. Wilson, R. Sun, J. Luz, 2005, Journal of molecular biology.

Toward a carbohydrate-based HIV-1 vaccine

D. Burton, R. Dwek, I. Wilson, 2006 .

Crystal structure of a non-canonical high affinity peptide complexed with MHC class I: a novel use of alternative anchors.

V. Apostolopoulos, I. Wilson, M. Plebanski, 2002, Journal of molecular biology.

Crystal structure of an H-2Kb-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove.

P. A. Peterson, D. Fremont, I. Wilson, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Design and Structure of an Engineered Disulfide-Stabilized Influenza Virus Hemagglutinin Trimer

I. Wilson, Peter S. Lee, Xueyong Zhu, 2015, Journal of Virology.

Antibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Binding Site

James E. Crowe, Andrew B. Ward, Xueyong Zhu, 2013, Journal of Virology.

Broadly neutralizing antibodies against influenza viruses.

N. S. Laursen, I. Wilson, 2013, Antiviral research.

Crystal structure of an MHC class I presented glycopeptide that generates carbohydrate-specific CTL.

I. Wilson, J. Speir, M. Jondal, 1999, Immunity.

Crystallization of murine major histocompatibility complex class I H-2Kb with single peptides.

P. A. Peterson, D. Fremont, I. Wilson, 1992, Journal of molecular biology.

Stabilization of amyloidogenic immunoglobulin light chains by small molecules

Steven J Brown, L. Kay, I. Wilson, 2019, Proceedings of the National Academy of Sciences.

Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth.

Jens Meiler, James E Crowe, David C Montefiori, 2015, The Journal of clinical investigation.

A variable light domain fluorogen activating protein homodimerizes to activate dimethylindole red.

I. Wilson, A. Waggoner, P. Berget, 2012, Biochemistry.

A Conformational Switch in Human Immunodeficiency Virus gp41 Revealed by the Structures of Overlapping Epitopes Recognized by Neutralizing Antibodies

D. Burton, I. Wilson, P. Dawson, 2009, Journal of Virology.

Structure determination of an anti-HIV-1 Fab 447-52D-peptide complex from an epitaxially twinned data set.

S. Zolla-Pazner, M. Gorny, I. Wilson, 2008, Acta crystallographica. Section D, Biological crystallography.

Structure of antibody F425-B4e8 in complex with a V3 peptide reveals a new binding mode for HIV-1 neutralization.

C. H. Bell, D. Burton, I. Wilson, 2008, Journal of molecular biology.

Specific recognition of a DNA immunogen by its elicited antibody.

Robyn L Stanfield, Ian A Wilson, Fernando A Goldbaum, 2007, Journal of molecular biology.

Crystal structures of a quorum-quenching antibody.

I. Wilson, E. Debler, K. Janda, 2007, Journal of molecular biology.

Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10.

Ian A Wilson, Dennis R Burton, Michael Zwick, 2007, Journal of molecular biology.

The Long Third Complementarity-Determining Region of the Heavy Chain Is Important in the Activity of the Broadly Neutralizing Anti-Human Immunodeficiency Virus Type 1 Antibody 2F5

H. Katinger, D. Burton, P. Parren, 2004, Journal of Virology.

Recurring conformation of the human immunodeficiency virus type 1 gp120 V3 loop.

I. Wilson, R. Stanfield, J. Ghiara, 2003, Virology.

A humanized aldolase antibody for selective chemotherapy and adaptor immunotherapy.

C. Barbas, R. Lerner, I. Wilson, 2003, Journal of molecular biology.

Contrasting IgG structures reveal extreme asymmetry and flexibility.

Robyn L Stanfield, Pauline M Rudd, Erica Ollmann Saphire, 2002, Journal of molecular biology.

Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs.

I. Wilson, R. Stanfield, E. Stura, 1999, Structure.

An antibody exo Diels-Alderase inhibitor complex at 1.95 angstrom resolution.

I. Wilson, K. Houk, A. Heine, 1998, Science.

Structure-based design of a constrained peptide mimic of the HIV-1 V3 loop neutralization site.

H. Dyson, I. Wilson, J. Ghiara, 1997, Journal of molecular biology.

Alanine scanning mutagenesis of an alphabeta T cell receptor: mapping the energy of antigen recognition.

K. Garcia, I. Wilson, D. Kranz, 1998, Immunity.

Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor.

Ian A Wilson, I. Wilson, Kendall A. Smith, 2006, Proceedings of the National Academy of Sciences of the United States of America.

A Peptide That Antagonizes TCR-Mediated Reactions with Both Syngeneic and Allogeneic Agonists: Functional and Structural Aspects1

Qing Ge, Markus G. Rudolph, Herman N. Eisen, 2004, The Journal of Immunology.

Crystal structures of two rat MHC class Ia (RT1-A) molecules that are associated differentially with peptide transporter alleles TAP-A and TAP-B.

I. Wilson, J. Trowsdale, M. Rudolph, 2002, Journal of molecular biology.

Correction: CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes

P. A. Peterson, K. Garcia, I. Wilson, 1997, Nature.

The diabetogenic mouse MHC class II molecule I-Ag7 is endowed with a switch that modulates TCR affinity.

Kenji Yoshida, Ian A Wilson, I. Wilson, 2010, The Journal of clinical investigation.

that modulates TCR affinity

I. Wilson, La Jolla, L. Teyton, 2010 .

Sequential mutations in hemagglutinins of influenza B virus isolates: definition of antigenic domains.

I. Wilson, J. Skehel, D. Wiley, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Different genetic barriers for resistance to HA stem antibodies in influenza H3 and H1 viruses

R. Lerner, I. Wilson, J. Bloom, 2020, Science.

Immunodominance and Antigenic Variation of Influenza Virus Hemagglutinin: Implications for Design of Universal Vaccine Immunogens.

I. Wilson, N. Wu, Seth J. Zost, 2019, The Journal of infectious diseases.

Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants

D. Burton, I. Wilson, N. Wu, 2021, Science.

Crystallization studies of glycosylated and unglycosylated human recombinant interleukin‐2

I. Wilson, C. Wilmot, J. Arevalo, 1992, Proteins.

Crystal structure of the murine NK cell–activating receptor NKG2D at 1.95 Å

D. Busch, I. Wilson, M. Rudolph, 2001, Nature Immunology.

Structural evidence for induced fit as a mechanism for antibody-antigen recognition.

I. Wilson, J. Rini, U. Schulze-Gahmen, 1994, Science.

Stapled HIV-1 Peptides Recapitulate Antigenic Structures and Engage Broadly Neutralizing Antibodies

I. Wilson, P. Kwong, G. Ofek, 2014, Nature Structural &Molecular Biology.

Atomic coordinates for triose phosphate isomerase from chicken muscle.

D W Banner, G A Petsko, G. Petsko, 1976, Biochemical and biophysical research communications.

Maturation of shark single-domain (IgNAR) antibodies: evidence for induced-fit binding.

I. Wilson, M. Flajnik, R. Stanfield, 2007, Journal of molecular biology.

A New Functional Domain of Guanine Nucleotide Dissociation Inhibitor (α‐GDI) Involved in Rab Recycling

I. Wilson, A. Heine, P. Kuhn, 2000, Traffic.

The Junctional Adhesion Molecule JAML Is a Costimulatory Receptor for Epithelial γδ T Cell Activation

I. Wilson, W. Fischer, R. Mills, 2010, Science.

Sequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain

I. Wilson, N. Wu, M. Yuan, 2021, Nature Communications.

Sequence signatures of two IGHV3-53/3-66 public clonotypes to SARS-CoV-2 receptor binding domain

I. Wilson, N. Wu, M. Yuan, 2021, bioRxiv.

Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape

Jonathan L. Schmid-Burgk, I. Wilson, P. Koenig, 2021, Science.

A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody

I. Wilson, N. Wu, D. Nemazee, 2020, bioRxiv.

SARS-CoV-2 Beta variant infection elicits potent lineage-specific and cross-reactive antibodies

I. Wilson, M. Hoelscher, D. Schmitz, 2021, bioRxiv.

Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants

D. Burton, I. Wilson, N. Wu, 2021, Science.

A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody

D. Burton, I. Wilson, N. Wu, 2020, PLoS pathogens.

Homologous and heterologous serological response to the N‐terminal domain of SARS‐CoV‐2 in humans and mice

J. Peiris, O. Tsang, I. Wilson, 2021, European journal of immunology.

NMR Based SARS-CoV-2 Antibody Screening

I. Wilson, M. Clarkson, W. Peti, 2021, Journal of the American Chemical Society.

Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques

B. Pulendran, G. Debnath, John P. Moore, 2018, PLoS pathogens.

A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans.

D. Burton, I. Wilson, Chi‐Huey Wong, 2016, Immunity.

HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies

Chaim A. Schramm, Kenneth H. Zhou, J. Yates, 2019, bioRxiv.

Crystal structure of a fully glycosylated HIV‐1 gp120 core reveals a stabilizing role for the glycan at Asn262

I. Wilson, P. Kwong, L. Kong, 2015, Proteins.

Integrity of Glycosylation Processing of a Glycan-Depleted Trimeric HIV-1 Immunogen Targeting Key B-Cell Lineages.

John P. Moore, I. Wilson, A. Ward, 2018, Journal of proteome research.

Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model

R. Fuller, R. Wyatt, D. Burton, 2017, Cell reports.

Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer.

I. Wilson, R. Stanfield, R. Sanders, 2015, Acta crystallographica. Section D, Biological crystallography.

Rapid and Robust Protection against Cocaine-Induced Lethality in Rats by the Bacterial Cocaine Esterase

I. Wilson, R. Sunahara, E. Jutkiewicz, 2006, Molecular Pharmacology.

A cross-neutralizing antibody between HIV-1 and influenza virus

I. Wilson, N. Wu, A. Ward, 2021, PLoS pathogens.

Broadly neutralizing antibodies against influenza virus and prospects for universal therapies.

I. Wilson, D. Ekiert, 2012, Current opinion in virology.

A Structurally Distinct Human Mycoplasma Protein that Generically Blocks Antigen-Antibody Union

Daniel R. Salomon, Richard A. Lerner, Andrew B. Ward, 2014, Science.

Crystal structure of mouse triggering receptor expressed on myeloid cells 1 (TREM-1) at 1.76 A.

I. Wilson, E. Debler, M. Kelker, 2004, Journal of molecular biology.

Crystal structure of human triggering receptor expressed on myeloid cells 1 (TREM-1) at 1.47 A.

K. Wüthrich, I. Wilson, W. Peti, 2004, Journal of molecular biology.

Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin

Jinquan Luo, Galina Obmolova, Andrew B. Ward, 2018, Science.

Structural Basis for Recognition of a Unique Epitope by a Human Anti-tau Antibody.

I. Wilson, J. Hoozemans, J. Wadia, 2018, Structure.

Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures

Sriram Subramaniam, Mario J. Borgnia, William C. Olson, 2011, Proceedings of the National Academy of Sciences.

Evolution of shape complementarity and catalytic efficiency from a primordial antibody template.

K N Houk, I. Wilson, D. Hilvert, 1999, Science.

Catalytic Antibody Structures: An Early Assessment

I. Wilson, A. Heine, M. Haynes, 1996 .

Complete reaction cycle of a cocaine catalytic antibody at atomic resolution.

I. Wilson, K. Janda, G. Kaufmann, 2006, Structure.

TOPSAN: a collaborative annotation environment for structural genomics

John C. Wooley, Constantina Bakolitsa, Adam Godzik, 2010, BMC Bioinformatics.

Crystal structure of a putative modulator of DNA gyrase (pmbA) from Thermotoga maritima at 1.95 Å resolution reveals a new fold

Mitchell D. Miller, A. Godzik, K. Hodgson, 2005, Proteins.

Observation of an Arsenic Adduct in an Acetyl Esterase Crystal Structure*

I. Wilson, N. Bruce, Xueyong Zhu, 2003, The Journal of Biological Chemistry.

Structural and functional analysis of the globular head domain of p115 provides insight into membrane tethering.

A. Godzik, I. Wilson, P. Rotkiewicz, 2009, Journal of molecular biology.

Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria

P. Schultz, I. Wilson, Rongsheng E. Wang, 2017, Nature chemical biology.

Stabilizing the CH2 Domain of an Antibody by Engineering in an Enhanced Aromatic Sequon.

I. Wilson, Wentao Chen, J. Kelly, 2016, ACS chemical biology.

Crystal structure of gamma-glutamyl phosphate reductase (TM0293) from Thermotoga maritima at 2.0 A resolution.

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins.

Crystal structure of γ‐glutamyl phosphate reductase (TM0293) from Thermotoga maritima at 2.0 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2003 .

Defining the Structural Basis for Allosteric Product Release from E. coli Dihydrofolate Reductase Using NMR Relaxation Dispersion

H. Dyson, P. Wright, I. Wilson, 2017, Journal of the American Chemical Society.

Structure and Function of Catalytic Antibodies

I. Wilson, N. Larsen, 2008 .

Structure of the γ-d-glutamyl-l-diamino acid endopeptidase YkfC from Bacillus cereus in complex with l-Ala-γ-d-Glu: insights into substrate recognition by NlpC/P60 cysteine peptidases

Mitchell D. Miller, A. Godzik, A. Deacon, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

Purification, sequence and crystallization of an anti-tissue factor Fab and its use for the crystallization of tissue factor

I. Wilson, R. Syed, E. Stura, 1992 .

X-ray crystallographic analysis of free and antigen-complexed Fab fragments to investigate structural basis of immune recognition.

I. Wilson, J. Rini, E. Stura, 1991, Methods in enzymology.

Structural aspects of antibodies and antibody-antigen complexes.

D. Fremont, I. Wilson, R. Stanfield, 2007, Ciba Foundation symposium.

I. Wilson, M. Taussig, D. Hilvert, 1996 .

Novel lamprey antibody recognizes terminal sulfated galactose epitopes on mammalian glycoproteins

Brantley R. Herrin, R. Cummings, I. Wilson, 2021, Communications biology.

Selection by site-directed antibodies of small regions of peptides which are ordered in water.

R. Lerner, H. Dyson, P. Wright, 2007, Ciba Foundation symposium.

The immunodominant site of a synthetic immunogen has a conformational preference in water for a type-II reverse turn

R. Lerner, H. Dyson, P. Wright, 1985, Nature.

Bacterially derived synthetic mimetics of mammalian oligomannose prime antibody responses that neutralize HIV infectivity

I. Wilson, S. Murrell, R. Pantophlet, 2017, Nature Communications.

A Unique and Conserved Neutralization Epitope in H5N1 Influenza Viruses Identified by an Antibody against the A/Goose/Guangdong/1/96 Hemagglutinin

I. Wilson, Kwok-Hung Chan, K. Yuen, 2013, Journal of Virology.

the 2009 H 1 N 1 Influenza Pandemic Hemagglutinin Receptor Specificity from Structural Characterization of the

I. Wilson, Corwin M. Nycholat, R. Xu, 2011 .

Recent avian H5N1 viruses exhibit increased propensity for acquiring human receptor specificity.

I. Wilson, J. Paulson, R. Donis, 2008, Journal of molecular biology.

Glycan microarray technologies: tools to survey host specificity of influenza viruses

Ian A. Wilson, James Stevens, James C. Paulson, 2006, Nature Reviews Microbiology.

Geometric structure of ion-induced displacement cascades in solids

F. Guinea, I. Wilson, E. Louis, 1987 .

Crystal structure of a single‐stranded DNA‐binding protein (TM0604) from Thermotoga maritima at 2.60 Å resolution

Adam Godzik, Henry van den Bedem, Slawomir K. Grzechnik, 2006, Proteins.

Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1

D. Burton, I. Wilson, W. Koff, 2010, Proceedings of the National Academy of Sciences.

Improved design of an antigen with enhanced specificity for the broadly HIV-neutralizing antibody b12.

D. Burton, I. Wilson, R. Pantophlet, 2004, Protein engineering, design & selection : PEDS.

Hyperglycosylated Mutants of Human Immunodeficiency Virus (HIV) Type 1 Monomeric gp120 as Novel Antigens for HIV Vaccine Design

Dennis R. Burton, Ian A. Wilson, D. Burton, 2003, Journal of Virology.

Fine Mapping of the Interaction of Neutralizing and Nonneutralizing Monoclonal Antibodies with the CD4 Binding Site of Human Immunodeficiency Virus Type 1 gp120

Paul W. H. I. Parren, Dennis R. Burton, Pascal Poignard, 2003, Journal of Virology.

An Insertion Mutation That Distorts Antibody Binding Site Architecture Enhances Function of a Human Antibody

I. Wilson, J. Crowe, D. Ekiert, 2011, mBio.

Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization

E. Go, H. Desaire, John P. Moore, 2017, Cell reports.

Hormone Receptor Mechanism of Activation of Protein Kinase JAK 2 by the Growth

Mara, Guillermo A. Gomez, I. Wilson, 2014 .

Structural Analysis of Toll-Like Receptors

I. Wilson, J. Choe, 2008 .

Crystallization and preliminary X-ray diffraction studies of a complex between interleukin-2 and a soluble form of the p55 component of the high affinity interleukin-2 receptor.

I. Wilson, E. Stura, G. Lambert, 1989, The Journal of biological chemistry.

Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer

R. Wyatt, I. Wilson, S. Sharma, 2018, Nature Communications.

Functional convergence of a germline-encoded neutralizing antibody response in rhesus macaques immunized with HCV envelope glycoproteins.

J. Bukh, I. Wilson, R. Stanfield, 2021, Immunity.

The Impact of Sustained Immunization Regimens on the Antibody Response to Oligomannose Glycans

A. Rodal, I. Wilson, D. Montefiori, 2020, ACS chemical biology.

Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design

I. Wilson, A. Ward, P. Poignard, 2018, Cell reports.

CD4-induced activation in a soluble HIV-1 Env trimer.

John P. Moore, I. Wilson, T. Matsui, 2014, Structure.

Reducing the immunodominant non-neutralizing V 3 response to HIV-1 Env trimers

John P. Moore, I. Wilson, A. Vecchione, 2017 .

Preliminary crystallographic data, primary sequence, and binding data for an anti-peptide Fab and its complex with a synthetic peptide from influenza virus hemagglutinin.

I. Wilson, J. Kenten, J. Rini, 1988, The Journal of biological chemistry.

Cross-reactive antibody response between SARS-CoV-2 and SARS-CoV infections

Nicholas C. Wu, Ian A. Wilson, L. Poon, 2020, bioRxiv.

Crystal Structure of mouse CD1d bound to the self ligand phosphatidylcholine

I. Wilson, M. Degano, M. Crispin, 2005 .

Crystal structure of a member of a novel family of dioxygenases (PF10014) reveals a conserved cupin fold and active site

Mitchell D. Miller, A. Godzik, A. Deacon, 2014, Proteins.

Broadly protective human antibodies that target the active site of influenza virus neuraminidase

I. Wilson, F. Krammer, M. McMahon, 2019, Science.

Receptor mimicry by antibody F045–092 facilitates universal binding to the H3 subtype of influenza virus

Y. Iba, Y. Kurosawa, I. Wilson, 2014, Nature Communications.

Title: Neutralizing antibody responses to an HIV envelope glycan hole are not easily broadened Running Title: Glycan hole strain specific HIV neutralizing responses Authors:

D. Burton, I. Wilson, H. Turner, 2019 .

Structural rationale for the broad neutralization of HIV-1 by human monoclonal antibody 447-52D.

Robyn L Stanfield, Ian A Wilson, Susan Zolla-Pazner, 2004, Structure.

A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity

I. Wilson, H. Wardemann, A. Valleriani, 2020, bioRxiv.

Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence

John P. Moore, M. V. van Breemen, I. Wilson, 2019, Nature Communications.

Structural Constraints Determine the Glycosylation of HIV-1 Envelope Trimers.

Ian A Wilson, Dennis R Burton, John P. Moore, 2015, Cell reports.

Preventing an Antigenically Disruptive Mutation in Egg-Based H3N2 Seasonal Influenza Vaccines by Mutational Incompatibility

I. Wilson, N. Wu, A. Thompson, 2019, Cell host & microbe.

A small-molecule fragment that emulates binding of receptor and broadly neutralizing antibodies to influenza A hemagglutinin

I. Wilson, R. Kadam, 2018, Proceedings of the National Academy of Sciences.

Potent peptidic fusion inhibitors of influenza virus

I. Wilson, R. Vreeken, Christophe Buyck, 2017, Science.

An alternate conformation of HCV E2 neutralizing face as an additional vaccine target

J. Bukh, I. Wilson, R. Stanfield, 2020, Science Advances.

Structural flexibility at a major conserved antibody target on hepatitis C virus E2 antigen

Virgil L. Woods, I. Wilson, A. Ward, 2016, Proceedings of the National Academy of Sciences.

Crystal structure of S‐adenosylmethionine:tRNA ribosyltransferase‐isomerase (QueA) from Thermotoga maritima at 2.0 Å resolution reveals a new fold

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2005, Proteins.

Crystal structure of an indigoidine synthase A (IndA)‐like protein (TM1464) from Thermotoga maritima at 1.90 Å resolution reveals a new fold

Mitchell D. Miller, A. Godzik, A. Deacon, 2005, Proteins.

Crystal structure of a formiminotetrahydrofolate cyclodeaminase (TM1560) from Thermotoga maritima at 2.80 Å resolution reveals a new fold

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2005, Proteins: Structure, Function, and Bioinformatics.

Crystal structure of a tandem cystathionine‐β‐synthase (CBS) domain protein (TM0935) from Thermotoga maritima at 1.87 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins.

Crystal structure of a novel Thermotoga maritima enzyme (TM1112) from the cupin family at 1.83 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins: Structure, Function, and Bioinformatics.

Crystal structure of a novel manganese‐containing cupin (TM1459) from Thermotoga maritima at 1.65 Å resolution

Mitchell D. Miller, A. Godzik, A. Deacon, 2004, Proteins.

Crystal structure of a putative oxalate decarboxylase (TM1287) from Thermotoga maritima at 1.95 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins.

Crystal structure of O‐acetylserine sulfhydrylase (TM0665) from Thermotoga maritima at 1.8 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins: Structure, Function, and Bioinformatics.

Crystal structure of a methionine aminopeptidase (TM1478) from Thermotoga maritima at 1.9 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins: Structure, Function, and Bioinformatics.

Crystal structure of a ribose‐5‐phosphate isomerase RpiB (TM1080) from Thermotoga maritima at 1.90 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins.

Crystal structure of an Udp‐n‐acetylmuramate‐alanine ligase MurC (TM0231) from Thermotoga maritima at 2.3 Å resolution

Mitchell D. Miller, A. Godzik, A. Deacon, 2004, Proteins.

Crystal structure of a type II quinolic acid phosphoribosyltransferase (TM1645) from Thermotoga maritima at 2.50 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins.

Crystal structure of a phosphoribosylaminoimidazole mutase PurE (TM0446) from Thermotoga maritima at 1.77‐Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins.

Crystal structure of an HEPN domain protein (TM0613) from Thermotoga maritima at 1.75 Å resolution

Mitchell D. Miller, A. Godzik, A. Deacon, 2004, Proteins.

Crystal structure of a putative glutamine amido transferase (TM1158) from Thermotoga maritima at 1.7 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins.

Crystal structure of a putative PII‐like signaling protein (TM0021) from Thermotoga maritima at 2.5 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2004, Proteins.

Structure-based design of a highly stable, covalently-linked SARS-CoV-2 spike trimer with improved structural properties and immunogenicity

I. Wilson, J. Snijder, E. Saphire, 2021, bioRxiv.

Multistate design of influenza antibodies improves affinity and breadth against seasonal viruses

Jens Meiler, Nicholas C. Wu, James E. Crowe, 2019, Proceedings of the National Academy of Sciences.

On the three-dimensional structure and catalytic mechanism of triose phosphate isomerase.

D W Banner, G A Petsko, G. Petsko, 1981, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Bacterial Glycosyltransferase-mediated Cell-surface Chemoenzymatic Glycan Editing: Methods and Applications

I. Wilson, N. Wu, Geramie Grande, 2018, bioRxiv.

H7N9 influenza virus neutralizing antibodies that possess few somatic mutations.

I. Wilson, J. Crowe, M. Rock, 2016, The Journal of clinical investigation.

Structural Basis for a Switch in Receptor Binding Specificity of Two H5N1 Hemagglutinin Mutants.

I. Wilson, R. Sasisekharan, Xueyong Zhu, 2015, Cell reports.

A Trojan horse with a sweet tooth

I. Wilson, R. Stanfield, 1995, Nature Structural Biology.

Alternative Recognition of the Conserved Stem Epitope in Influenza A Virus Hemagglutinin by a VH3-30-Encoded Heterosubtypic Antibody

I. Wilson, C. Dreyfus, L. Hangartner, 2014, Journal of Virology.

Reactivation of methionine synthase from Thermotoga maritima (TM0268) requires the downstream gene product TM0269

I. Wilson, R. Matthews, S. Lesley, 2007, Protein science : a publication of the Protein Society.

Protein Production and Crystallization at the Joint Center for Structural Genomics

Scott A. Lesley, Ian A. Wilson, I. Wilson, 2005, Journal of Structural and Functional Genomics.

Discovery of Potent Coumarin-Based Kinetic Stabilizers of Amyloidogenic Immunoglobulin Light Chains Using Structure-Based Design.

H. M. Petrassi, I. Wilson, J. Kelly, 2021, Journal of medicinal chemistry.

Crystal structure of a human immunodeficiency virus type 1 neutralizing antibody, 50.1, in complex with its V3 loop peptide antigen.

R L Stanfield, I. Wilson, R. Stanfield, 1993, Proceedings of the National Academy of Sciences of the United States of America.

The structure of Haemophilus influenzae prephenate dehydrogenase suggests unique features of bifunctional TyrA enzymes

Mitchell D. Miller, A. Godzik, A. Deacon, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

On the protein crystal chemistry of chloroplatinite ions: general principles and interactions with triose phosphate isomerase.

G. Petsko, D. Phillips, I. Wilson, 1978, Journal of molecular biology.

Immunological memory to hyperphosphorylated tau in asymptomatic individuals

I. Wilson, Z. Fulton, J. Hoozemans, 2017, Acta Neuropathologica.

Structure and Function of a Novel ld-Carboxypeptidase A Involved in Peptidoglycan Recycling

Mitchell D. Miller, A. Godzik, A. Deacon, 2013, Journal of bacteriology.

Preferential Recognition of Avian-Like Receptors in Human Influenza A H7N9 Viruses

I. Wilson, Corwin M. Nycholat, J. Paulson, 2013, Science.

Crystal structure of a peptide complex of anti-influenza peptide antibody Fab 26/9. Comparison of two different antibodies bound to the same peptide antigen.

R A Houghten, R. Balderas, I. Wilson, 1994, Journal of molecular biology.

Antibody 2G12 Recognizes Di-Mannose Equivalently in Domain- and Nondomain-Exchanged Forms but Only Binds the HIV-1 Glycan Shield if Domain Exchanged

D. Burton, I. Wilson, Z. Fulton, 2010, Journal of Virology.

Dynamic Local Polymorphisms in the Gbx1 Homeodomain Induced by DNA Binding.

K. Wüthrich, I. Wilson, P. Serrano, 2016, Structure.

Potent Kinetic Stabilizers That Prevent Transthyretin-Mediated Cardiomyocyte Proteotoxicity

I. Graef, I. Wilson, J. Kelly, 2011, Science Translational Medicine.

A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.

Steven M. Johnson, I. Wilson, J. Kelly, 2010, Journal of the American Chemical Society.

Chemoselective small molecules that covalently modify one lysine in a non-enzyme protein in plasma.

I. Wilson, J. Kelly, Sungwook Choi, 2010, Nature chemical biology.

Toward optimization of the second aryl substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies.

Steven M. Johnson, I. Wilson, J. Kelly, 2009, Journal of medicinal chemistry.

Structure of Hepatitis C Virus Envelope Glycoprotein E1 Antigenic Site 314-324 in Complex with Antibody IGH526.

I. Wilson, P. Dawson, R. Stanfield, 2015, Journal of molecular biology.

Table of Contents / barcode

I. Wilson, P. Kuhn, S. Makino, 2011, Journal of Structural Biology.

Structure of Bacteroides thetaiotaomicron BT2081 at 2.05 Å resolution: the first structural representative of a new protein family that may play a role in carbohydrate metabolism

Mitchell D. Miller, A. Godzik, A. Deacon, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structural insights into the function of the Rab GDI superfamily.

I. Wilson, W. Balch, Shih-Kwang Wu, 1996, Trends in biochemical sciences.

pH-dependent interdomain tethers of CD1b regulate its antigen capture.

L. F. Murga, M. Ondrechen, I. Wilson, 2008, Immunity.

Crystal structure of the principal neutralization site of HIV-1.

I. Wilson, R. Stanfield, E. Stura, 1994, Science.

Analysis of an anti-progesterone antibody: variable crystal morphology of the Fab' and steroid-Fab' complexes.

I. Wilson, M. Taussig, J. Arevalo, 1987, Immunology.

Improving the Expression and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers by Targeted Sequence Changes

John P. Moore, I. Wilson, A. Ward, 2017, Journal of Virology.

N-glycolylneuraminic acid binding of avian H7 influenza A viruses

I. Wilson, C. Russell, G. Boons, 2020, bioRxiv.

Intermonomer disulfide bonds impair the fusion activity of influenza virus hemagglutinin

I. Wilson, D. Bodian, J. White, 1992, Journal of virology.

Influences on the Design and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers

E. Go, H. Desaire, John P. Moore, 2015, Journal of Virology.

Microscopyn Single-Particle Electron Soluble and Fully Glycosylated HIV-1 Env in Complex with 2 Structure of 2G12 Fab

John P. Moore, I. Wilson, C. D. Murin, 2014 .

Molecular Recognition of HIV Glycans by Antibodies

I. Wilson, R. Stanfield, L. Kong, 2014 .

Stable 293 T and CHO cell lines expressing cleaved, stable HIV-1 envelope glycoprotein trimers for structural and vaccine studies

John P. Moore, I. Wilson, T. Ketas, 2014, Retrovirology.

Structural Insights into the Recognition of Phosphopeptide by the FHA Domain of Kanadaptin

A. Deacon, I. Wilson, S. Lesley, 2014, PloS one.

The structure of the first representative of Pfam family PF09836 reveals a two-domain organization and suggests involvement in transcriptional regulation

Slawomir K. Grzechnik, Mitchell D. Miller, N. Grishin, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

Cross-reactive Antibody Response between SARS-CoV-2 and SARS-CoV Infections

J. Peiris, L. Poon, O. Tsang, 2020, Cell Reports.

Structure and mutational analysis of Rab GDP-dissociation inhibitor

I. Wilson, W. Balch, E. Stura, 1996, Nature.

Structural basis of broad HIV neutralization by a vaccine-induced cow antibody

D. Burton, I. Wilson, A. Ward, 2020, Science Advances.

Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor binding head domains

I. Wilson, J. Pallesen, J. Crowe, 2018, bioRxiv.

Stabilization of the V2 loop improves the presentation of V2 loop–associated broadly neutralizing antibody epitopes on HIV-1 envelope trimers

E. Go, H. Desaire, John P. Moore, 2019, The Journal of Biological Chemistry.

Structural and Biochemical Characterization of Cysteinylation in Broadly Neutralizing Antibodies to HIV-1

I. Wilson, O. Omorodion, 2021, Journal of molecular biology.

Antibody 27F3 Broadly Targets Influenza A Group 1 and 2 Hemagglutinins through a Further Variation in VH1-69 Antibody Orientation on the HA Stem.

R. Lerner, I. Wilson, N. Wu, 2017, Cell reports.

Functional human IgA targets a conserved site on malaria sporozoites

Peter D. Crompton, I. Wilson, P. Sinnis, 2021, Science Translational Medicine.

A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response

David Baker, Andrew B. Ward, Ian A. Wilson, 2016, PLoS pathogens.

Structure of a putative NTP pyrophosphohydrolase: YP_001813558.1 from Exiguobacterium sibiricum 255-15

Mitchell D. Miller, A. Godzik, A. Deacon, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity

D. Burton, I. Wilson, M. Wormald, 2010, Proceedings of the National Academy of Sciences.

CD1 assembly and the formation of CD1-antigen complexes.

I. Wilson, D. Zajonc, M. Brenner, 2005, Current opinion in immunology.

Inhibitory antibodies identify unique sites of therapeutic vulnerability in rhinovirus and other enteroviruses

R. Lerner, I. Wilson, Jia Xie, 2020, Proceedings of the National Academy of Sciences.

Structure of a membrane-attack complex/perforin (MACPF) family protein from the human gut symbiont Bacteroides thetaiotaomicron

Herbert L. Axelrod, Constantina Bakolitsa, Adam Godzik, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structure and Function of the First Full-Length Murein Peptide Ligase (Mpl) Cell Wall Recycling Protein

Adam Godzik, Hsiu-Ju Chiu, Debanu Das, 2011, PloS one.

The crystal structure of CD8 in complex with YTS156.7.7 Fab and interaction with other CD8 antibodies define the binding mode of CD8 alphabeta to MHC class I.

I. Wilson, L. Teyton, D. Shore, 2008, Journal of molecular biology.

Promiscuous Glycan Site Recognition by Antibodies to the High-Mannose Patch of gp120 Broadens Neutralization of HIV

William R. Schief, Michael S. Seaman, Dennis R. Burton, 2014, Science Translational Medicine.

Crystal Structures of Human Immunodeficiency Virus Type 1 (HIV-1) Neutralizing Antibody 2219 in Complex with Three Different V3 Peptides Reveal a New Binding Mode for HIV-1 Cross-Reactivity

S. Zolla-Pazner, M. Gorny, I. Wilson, 2006, Journal of Virology.

A single mutation in Taiwanese H6N1 influenza hemagglutinin switches binding to human‐type receptors

M. V. van Breemen, I. Wilson, A. Thompson, 2017, EMBO molecular medicine.

VH1-69 antiviral broadly neutralizing antibodies: genetics, structures, and relevance to rational vaccine design.

I. Wilson, M. Law, N. Tzarum, 2019, Current opinion in virology.

Major antigenic site B of human influenza H3N2 viruses has an evolving local fitness landscape

I. Wilson, N. Wu, J. Otwinowski, 2020, Nature Communications.

A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site

R. Lerner, I. Wilson, N. Wu, 2018, Nature Communications.

Probing the antigenicity of hepatitis C virus envelope glycoprotein complex by high-throughput mutagenesis

Johnathan D. Guest, I. Wilson, L. Kong, 2017, PLoS pathogens.

Immune recognition of viral antigens.

D. Fremont, D. Jewell, I. Wilson, 1994, Infectious agents and disease.

The carbohydrate epitope of the neutralizing anti-HIV-1 antibody 2G12.

H. Katinger, D. Burton, R. Dwek, 2003, Advances in experimental medicine and biology.

Correction: Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design

D. Burton, I. Wilson, W. Schief, 2016, PLoS pathogens.

X-Ray Crystallographic Studies of Antibody–Peptide Complexes

I. Wilson, R. Stanfield, 1993 .

Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies.

I. Wilson, R. Stanfield, Vaughn V. Smider, 2016, Science immunology.

A common antigenic motif recognized by naturally occurring human VH5–51/VL4–1 anti-tau antibodies with distinct functionalities

Martin H. Koldijk, S. Steinbacher, I. Wilson, 2018, Acta neuropathologica communications.

Dlx5 Homeodomain:DNA Complex: Structure, Binding and Effect of Mutations Related to Split Hand and Foot Malformation Syndrome.

A. Deacon, R. Fletterick, K. Wüthrich, 2016, Journal of molecular biology.

Crystal structure of NMA1982 from Neisseria meningitidis at 1.5 Å resolution provides a structural scaffold for nonclassical, eukaryotic‐like phosphatases

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2007, Proteins.

An analysis of the structure of triose phosphate isomerase and its comparison with lactate dehydrogenase.

M. Sternberg, J. Thornton, D. Phillips, 1978, Journal of molecular biology.

Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies

I. Wilson, R. Stanfield, Vaughn V. Smider, 2016, Science Immunology.

Antigenic and Immunogenic Study of Membrane-Proximal External Region-Grafted gp120 Antigens by a DNA Prime-Protein Boost Immunization Strategy

D. Burton, I. Wilson, M. Law, 2007, Journal of Virology.

Comparison of NMR and crystal structures for the proteins TM1112 and TM1367

K. Wüthrich, I. Wilson, P. Serrano, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structural studies of human HIV-1 V3 antibodies.

I. Wilson, R. Stanfield, 2006, Human antibodies.

Structural insights into the design of novel anti-influenza therapies

I. Wilson, N. Wu, 2018, Nature Structural & Molecular Biology.

Semi-quantitative models for identifying potent and selective transthyretin amyloidogenesis inhibitors.

Steven M. Johnson, I. Wilson, J. Kelly, 2017, Bioorganic & medicinal chemistry letters.

Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification

I. Wilson, N. Wu, Jia Xie, 2019, Nature Communications.

Monoclonal antibodies against an identical short peptide sequence shared by two unrelated proteins.

I. Wilson, U. Schulze-Gahmen, 1989, Peptide research.

Structural origins of efficient proton abstraction from carbon by a catalytic antibody.

Donald Hilvert, Ian A Wilson, I. Wilson, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Crystal structure of a cocaine-binding antibody.

A Heine, B Zhou, I. Wilson, 2001, Journal of molecular biology.

Receptor Binding Site H1N1 Influenza Virus Hemagglutinin Antibody Recognition of the Pandemic

N. S. Laursen, I. Wilson, J. Crowe, 2013 .

NATURE BIOTECHNOLOGY | RESEARCH | ARTICLE

Timothy A. Whitehead, Hetunandan Kamisetty, I. Wilson, 2012 .

8 – Structural Studies of Antipeptide Antibodies

I. Wilson, R. Stanfield, J. Rini, 1990 .

I. Wilson, D. Hilvert, P. Verdino, 2008, Proceedings of the National Academy of Sciences.

Crystallographic analysis of the three-dimensional structure of baboon alpha-lactalbumin at low resolution. Homology with lysozyme.

M. Sundaralingam, D. Stuart, D. Phillips, 1987, The Biochemical journal.

Complex Moieties in the Recognition of a CD 1-Lipid Residues and Lipid Antigen Hydrophilic Complementarity-Determining Region Fine Specificity of TCR

I. Wilson, G. Besra, M. Degano, 2002 .

An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket

I. Wilson, D. Hilvert, R. Müller, 2009, Proceedings of the National Academy of Sciences.

Correction: Structure of an MmyB-Like Regulator from C. aurantiacus, Member of a New Transcription Factor Family Linked to Antibiotic Metabolism in Actinomycetes

Mitchell D. Miller, A. Godzik, A. Deacon, 2012, PLoS ONE.

Clinical Correlations of Transcriptional Profile in Patients Infected With Avian Influenza H7N9 Virus

I. Wilson, Rongchang Chen, N. Wu, 2018, The Journal of infectious diseases.

Unraveling the mysteries of gammadelta T cell recognition.

I. Wilson, R. Stanfield, 2001, Nature immunology.

Structural Basis for Ligand Recognition and Discrimination of a Quorum-quenching Antibody*

I. Wilson, K. Janda, G. Kaufmann, 2011, The Journal of Biological Chemistry.

Networks link antigenic and receptor-binding sites of influenza hemagglutinin: Mechanistic insight into fitter strain propagation

I. Wilson, V. Sasisekharan, S. Raguram, 2011, Scientific reports.

Corrigendum: Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors

Lucy A. Perrone, I. Wilson, E. Altschuler, 2012, Nature.

The structure of the influenza virus haemagglutinin glycoprotein at 3 Ã resolution

Ian A. Wilson, Don C. Wiley, I. Wilson, 1981 .

Detailed analysis of the free and bound conformations of an antibody. X-ray structures of Fab 17/9 and three different Fab-peptide complexes.

I. Wilson, J. Rini, U. Schulze-Gahmen, 1993, Journal of molecular biology.

Direct observation of an enamine intermediate in amine catalysis.

R. Lerner, I. Wilson, F. Tanaka, 2009, Journal of the American Chemical Society.

Bifunctional coumarin derivatives that inhibit transthyretin amyloidogenesis and serve as fluorescent transthyretin folding sensors.

I. Wilson, J. Kelly, Sungwook Choi, 2013, Chemical communications.

Industrializing Structural Biology

Raymond C. Stevens, Ian A. Wilson, R. Stevens, 2001, Science.

Crystallization and preliminary crystallographic data for class I deoxyribose‐5‐phosphate aldolase from Escherichia coli: An Application of Reverse Screening

I. Wilson, Chi‐Huey Wong, E. Stura, 1995, Proteins.

Crystallization and preliminary structural studies of a chorismate mutase catalytic antibody complexed with a transition state analog

I. Wilson, D. Hilvert, E. Stura, 1994 .

Genome, Proteome and the Quest for a Full Structure–Function Description of an Organism

A. Godzik, I. Wilson, 2013 .

Morals and Markets

L. Stamatatos, D. Burton, I. Wilson, 2013 .

from in the Gut

A. Godzik, A. Deacon, I. Wilson, 2016 .

Ligands in PSI structures

Herbert L. Axelrod, Hsiu-Ju Chiu, Andrew Morse, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

Thermotoga maritima of Three-Dimensional Structural View of the Central Metabolic Network

Ines Thiele, Ying Zhang, Adam Godzik, 2011 .

The Structure of an Aldehyde Decarbonylase from Prochlorococcus Marinus Implicated in Biofuel Synthesis Indicates an Octadecanoic Acid Ligand Coordinated to a Di-Iron Catalytic Center∗

A. Deacon, I. Wilson, H. Axelrod, 2012 .

Structural basis for differential recognition of phosphohistidine-containing peptides by 1-pHis and 3-pHis monoclonal antibodies

I. Wilson, T. Hunter, R. Stanfield, 2021, Proceedings of the National Academy of Sciences.

Antibody responses to viral infections: a structural perspective across three different enveloped viruses

I. Wilson, C. D. Murin, A. Ward, 2019, Nature Microbiology.

A structural analysis of M protein in coronavirus assembly and morphology

I. Wilson, B. Neuman, M. Buchmeier, 2010, Journal of Structural Biology.

Immune versus natural selection: antibody aldolases with enzymic rates but broader scope.

R. Lerner, I. Wilson, C. Barbas, 1997, Science.

Common antigenic motif recognized by human VH5-51/VL4-1 tau antibodies with distinct functionalities

Martin H. Koldijk, S. Steinbacher, I. Wilson, 2018, bioRxiv.

JAML and CAR: Two more players in T-cell activation

I. Wilson, P. Verdino, 2011, Cell cycle.

Crystal structure of homoserine O‐succinyltransferase from Bacillus cereus at 2.4 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2007, Proteins.

COPII-dependent export of cystic fibrosis transmembrane conductance regulator from the ER uses a di-acidic exit code

J. Riordan, I. Wilson, Xiaodong Wang, 2004, The Journal of cell biology.

Bioprocessing of chemically stabilized sulfhydryl groups of human J-chain protein in Escherichia coli

I. Wilson, M. Redwan, S. Matar, 2004 .

Crystal Structure and Activity Studies of the C11 Cysteine Peptidase from Parabacteroides merdae in the Human Gut Microbiome

A. Godzik, A. Deacon, I. Wilson, 2016, The Journal of Biological Chemistry.

Activation Volumes for Solid-Solid Transformations in Nanocrystals

R. Lerner, W. Goddard, I. Wilson, 2001, Science.

Changes in the conformation of inf the pH optimum of virus-mediated (virus glycoprotein/lipid binding/detergent binding)

I. Wilson, J. Skehel, D. Wiley, 2016 .

Crystal structure of the Fic (Filamentation induced by cAMP) family protein SO4266 (gi|24375750) from Shewanella oneidensis MR‐1 at 1.6 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2009, Proteins.

Crystal structure of a glycerate kinase (TM1585) from Thermotoga maritima at 2.70 Å resolution reveals a new fold

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2006, Proteins.

Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification

I. Wilson, N. Wu, Jia Xie, 2019, Nature Communications.

Crystal structure of an anti-idiotype variable lymphocyte receptor.

Brantley R. Herrin, I. Wilson, M. Cooper, 2017, Acta crystallographica. Section F, Structural biology communications.

Structural requirements for antigen presentation by mouse CD1.

I. Wilson, M. Degano, H. Iijima, 2000, Proceedings of the National Academy of Sciences of the United States of America.

The effects of antibodies on stilbene excited-state energetics.

P. Schultz, I. Wilson, E. Debler, 2006, Angewandte Chemie.

Crystal structure of 2‐keto‐3‐deoxygluconate kinase (TM0067) from Thermotoga maritima at 2.05 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2008, Proteins: Structure, Function, and Bioinformatics.

Antibody Structure.

I. Wilson, R. Stanfield, 2014, Microbiology spectrum.

Stapled HIV-1 Peptides Recapitulate Antigenic Structures and Engage Broadly Neutralizing Antibodies

I. Wilson, P. Kwong, G. Ofek, 2014, Nature Structural &Molecular Biology.

Hemagglutinin homologue from H17N10 bat influenza virus exhibits divergent receptor-binding and pH-dependent fusion activities

I. Wilson, J. Paulson, S. Tong, 2013, Proceedings of the National Academy of Sciences.

Comparison of NMR and crystal structures highlights conformational isomerism in protein active sites

K. Wüthrich, I. Wilson, P. Serrano, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

Aromatic sulfonyl fluorides covalently kinetically stabilize transthyretin to prevent amyloidogenesis while affording a fluorescent conjugate.

I. Wilson, E. Powers, N. Grimster, 2013, Journal of the American Chemical Society.

Adaptive mutations alter antibody structure and dynamics during affinity maturation.

I. Wilson, M. Oda, R. Stanfield, 2015, Biochemistry.

Structural basis of influenza virus fusion inhibition by the antiviral drug Arbidol

I. Wilson, R. Kadam, 2016, Proceedings of the National Academy of Sciences.

A Native-Like SOSIP.664 Trimer Based on an HIV-1 Subtype B env Gene

John P. Moore, D. Burton, I. Wilson, 2015, Journal of Virology.

Influences on Trimerization and Aggregation of Soluble, Cleaved HIV-1 SOSIP Envelope Glycoprotein

John P. Moore, I. Wilson, A. Ward, 2013, Journal of Virology.

Structural Basis for Ligand Recognition and Discrimination of a Quorum-quenching Antibody*

I. Wilson, K. Janda, G. Kaufmann, 2011, The Journal of Biological Chemistry.

Reshaping Antibody Diversity

P. Schultz, I. Wilson, A. Torkamani, 2013, Cell.

H7N9 influenza virus neutralizing antibodies that possess few somatic mutations.

I. Wilson, J. Crowe, M. Rock, 2016, The Journal of clinical investigation.

Crystal structure of a putative NADPH‐dependent oxidoreductase (GI: 18204011) from mouse at 2.10 Å resolution

Adam Godzik, Henry van den Bedem, Slawomir K. Grzechnik, 2004, Proteins.

A conserved fold for fimbrial components revealed by the crystal structure of a putative fimbrial assembly protein (BT1062) from Bacteroides thetaiotaomicron at 2.2 Å resolution

Mitchell D. Miller, A. Godzik, A. Deacon, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

Semi-quantitative models for identifying potent and selective transthyretin amyloidogenesis inhibitors.

Steven M. Johnson, I. Wilson, E. Powers, 2017, Bioorganic & medicinal chemistry letters.

VLR Recognition of TLR5 Expands the Molecular Characterization of Protein Antigen Binding by Non-Ig-based Antibodies.

Brantley R. Herrin, I. Wilson, M. Cooper, 2018, Journal of molecular biology.

Crystallographic and biochemical analysis of cocaine-degrading antibody 15A10.

I. Wilson, A. Mittal, D. Landry, 2004, Biochemistry.

Crystal structure of the B41 SOSIP.664 Env trimer with PGT124 and 35O22 Fabs, in P23 space group

John P. Moore, I. Wilson, A. Ward, 2019 .

Potent Kinetic Stabilizers That Prevent Transthyretin-Mediated Cardiomyocyte Proteotoxicity

I. Graef, I. Wilson, E. Powers, 2011, Science Translational Medicine.

Receptor mimicry by antibody F045–092 facilitates universal binding to the H3 subtype of influenza virus

Y. Iba, Y. Kurosawa, I. Wilson, 2014, Nature Communications.

Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques

B. Pulendran, John P. Moore, I. Wilson, 2018, PLoS pathogens.

Cofactor‐induced reversible folding of Flavodoxin‐4 from Lactobacillus acidophilus

A. Godzik, A. Deacon, K. Wüthrich, 2015, Protein science : a publication of the Protein Society.

Structural basis for the stabilization of amyloidogenic immunoglobulin light chains by hydantoins.

L. Kay, I. Wilson, Stefano Forli, 2020, Bioorganic & medicinal chemistry letters.

Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth.

Jordan R. Willis, I. Wilson, D. Montefiori, 2015, The Journal of clinical investigation.

Crystal structure of 2‐phosphosulfolactate phosphatase (ComB) from Clostridium acetobutylicum at 2.6 Å resolution reveals a new fold with a novel active site

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2006, Proteins.

Crystal structure of acireductone dioxygenase (ARD) from Mus musculus at 2.06 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2006 .

Crystal structure of virulence factor CJ0248 from Campylobacter jejuni at 2.25 Å resolution reveals a new fold

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2005, Proteins.

Crystal structure of the global regulatory protein CsrA from Pseudomonas putida at 2.05 Å resolution reveals a new fold

Slawomir K. Grzechnik, Mitchell D. Miller, A. Godzik, 2005, Proteins.

Crystal structure of a non-canonical low-affinity peptide complexed with MHC class I: a new approach for vaccine design.

V. Apostolopoulos, I. Wilson, M. Plebanski, 2002, Journal of Molecular Biology.

Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.

I. Wilson, R. Stanfield, A. Irimia, 2016, Immunity.

Structural Basis of TLR5-Flagellin Recognition and Signaling

I. Wilson, A. Osterman, A. Gudkov, 2012, Science.

Antibody 2G12 Recognizes Di-Mannose Equivalently in Domain- and Nondomain-Exchanged Forms but Only Binds the HIV-1 Glycan Shield if Domain Exchanged

D. Burton, I. Wilson, Z. Fulton, 2010, Journal of Virology.

Structural Biology and Crystallization Communications the Structure of Haemophilus Influenzae Prephenate Dehydrogenase Suggests Unique Features of Bifunctional Tyra Enzymes

Mitchell D. Miller, A. Godzik, A. Deacon, 2022 .

Studies on the Structure and Activities of Influenza Virus Haemagglutinin

I. Wilson, J. Skehel, D. Wiley, 1984 .

Crystal structure of a novel Sm‐like protein of putative cyanophage origin at 2.60 Å resolution

Slawomir K. Grzechnik, Mitchell D. Miller, K. D. Murphy, 2009, Proteins.

New Design of MHC Class II Tetramers to Accommodate Fundamental Principles of Antigen Presentation1

K. Garcia, I. Wilson, J. Altman, 2009, The Journal of Immunology.

Outcome of a workshop on applications of protein models in biomedical research.

Roland L. Dunbrack, David T. Jones, M. Levitt, 2009, Structure.

The Structure of Mlc Titration Factor A (MtfA/YeeI) Reveals a Prototypical Zinc Metallopeptidase Related to Anthrax Lethal Factor

Adam Godzik, Hsiu-Ju Chiu, Qingping Xu, 2012, Journal of bacteriology.

Multistate design of influenza antibodies improves affinity and breadth against seasonal viruses

I. Wilson, J. Meiler, J. Crowe, 2019, Proceedings of the National Academy of Sciences.

Unique Structural Features of Influenza Virus H15 Hemagglutinin

I. Wilson, Corwin M. Nycholat, J. Paulson, 2017, Journal of Virology.

Integrative Structural Biology

A. Sali, I. Wilson, A. Ward, 2013, Science.