A. Gnatt

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Transcription Mechanism Architecture of RNA Polymerase II and Implications

P. Cramer, D. Bushnell, Jianhua Fu, 2010 .

Structural Basis of Transcription: An RNA Polymerase II Elongation Complex at 3.3 Å Resolution

P. Cramer, D. Bushnell, A. Gnatt, 2001, Science.

Sensitivity of Mitochondrial Transcription and Resistance of RNA Polymerase II Dependent Nuclear Transcription to Antiviral Ribonucleosides

J. Arnold, C. Cameron, A. Gnatt, 2012, PLoS pathogens.

Oncogene PKC&egr; controls INrf2–Nrf2 interaction in normal and cancer cells through phosphorylation of INrf2

A. Gnatt, S. Niture, A. Jaiswal, 2013, Journal of Cell Science.

Molecular biological search for human genes encoding cholinesterases

A. Gnatt, H. Soreq, 1987, Molecular Neurobiology.

Site‐Directed Mutagenesis of Active Site Residues Reveals Plasticity of Human Butyrylcholinesterase in Substrate and Inhibitor Interactions

A. Gnatt, H. Soreq, A. Yaron, 1994, Journal of neurochemistry.

Differential Blocking Effects of the Acetaldehyde-derived DNA Lesion N2-Ethyl-2′-deoxyguanosine on Transcription by Multisubunit and Single Subunit RNA Polymerases*

A. Gnatt, P. J. Brooks, Xiaopeng Hu, 2008, Journal of Biological Chemistry.

Isolation and characterization of full-length cDNA clones coding for cholinesterase from fetal human tissues.

A. Gnatt, H. Soreq, D. Zevin-Sonkin, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Human acetylcholinesterase and butyrylcholinesterase are encoded by two distinct genes

A. Gnatt, H. Soreq, J. Lieman-Hurwitz, 1991, Cellular and Molecular Neurobiology.

Structure-Function Relationships, In Vivo Mutability and Gene Amplification in Human Cholinesterases, Targets for Organophosphorous Poisons

A. Gnatt, H. Soreq, E. Lev-Lehman, 1991 .

Expression of alternatively terminated unusual human butyrylcholinesterase messenger RNA transcripts, mapping to chromosome 3q26-ter, in nervous system tumors.

A. Gnatt, H. Soreq, J. Lieman-Hurwitz, 1990, Cancer research.

Aspartate‐70 to glycine substitution confers resistance to naturally occurring and synthetic anionic‐site ligands on inovo produced human butyrylcholinesterase

A. Gnatt, H. Soreq, L. Neville, 1990, Journal of neuroscience research.

Knockdown of TFIIS by RNA silencing inhibits cancer cell proliferation and induces apoptosis

R. Puri, A. Gnatt, J. Catalano, 2008, BMC Cancer.

Oncogene PKC ε controls INrf 2 : Nrf 2 interaction in normal and cancer cells through INrf 2 phosphorylation

A. Gnatt, S. Niture, A. Jaiswal, 2013 .

Use of synthetic oligodeoxynucleotide probes for the isolation of a human cholinesterase cDNA clone

A. Gnatt, H. Soreq, R. Koch, 1986, Journal of neuroscience research.

Molecular Dissection of Functional Domains in Human Cholinesterases Expressed in Microinjected Xenopus Oocytes

A. Gnatt, Y. Loewenstein, H. Soreq, 1992 .

A Mediator-responsive form of metazoan RNA polymerase II.

A. Gnatt, J. Catalano, R. Roeder, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Intramolecular relationships in cholinesterases revealed by oocyte expression of site‐directed and natural variants of human BCHE.

A. Gnatt, H. Soreq, S. Seidman, 1992, The EMBO journal.

Testicular Gene Amplification and Impaired BCHE Transcription Induced in Transgenic Mice by the Human BCHE Coding Sequence

A. Gnatt, H. Soreq, M. Shani, 1992 .

Excavations into the active-site gorge of cholinesterases.

A. Gnatt, H. Soreq, L. Neville, 1992, Trends in biochemical sciences.

Molecular cloning and construction of the coding region for human acetylcholinesterase reveals a G + C-rich attenuating structure.

A. Gnatt, H. Soreq, E. Lev-Lehman, 1990, Proceedings of the National Academy of Sciences of the United States of America.

STRUCTURE-FUNCTION RELATIONSHIP STUDIES IN HUMAN CHOLINESTERASES AS AN APPROACH FOR EVALUATING POTENTIAL PHARMACOTHERAPEUTIC AND/OR TOXICITY EFFECTS OF CHOLINERGIC DRUGS

A. Gnatt, H. Soreq, Shlomo Seidman, 1991 .

Architecture of RNA polymerase II and implications for the transcription mechanism.

P. Cramer, D. Bushnell, A. Gnatt, 2000, Science.

Formation and Crystallization of Yeast RNA Polymerase II Elongation Complexes*

A. Gnatt, R. Kornberg, Jia-Luo Fu, 1997, The Journal of Biological Chemistry.

Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions

A. Gnatt, Dong Wang, M. Kashlev, 2015, Proceedings of the National Academy of Sciences.

Yeast RNA Polymerase II at 5 Å Resolution

Grant J. Jensen, Jianhua Fu, Richard R. Burgess, 1999, Cell.

Electron Crystal Structure of an RNA Polymerase II Transcription Elongation Complex

G. Jensen, Jianhua Fu, A. Gnatt, 1999, Cell.

Fcp1 directly recognizes the C-terminal domain (CTD) and interacts with a site on RNA polymerase II distinct from the CTD.

Jianhua Fu, A. Gnatt, S. Shuman, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Elongation by RNA polymerase II: structure-function relationship.

A. Gnatt, 2002, Biochimica et biophysica acta.

Functional association of Gdown1 with RNA polymerase II poised on human genes.

R. Young, A. Gnatt, P. Rahl, 2012, Molecular cell.

Regulation of mammalian transcription by Gdown1 through a novel steric crosstalk revealed by cryo‐EM

Chun-Hsiung Wang, Yi-Min Wu, Jen-Wei Chang, 2012, The EMBO journal.

Transcriptional regulation by Pol II(G) involving mediator and competitive interactions of Gdown1 and TFIIF with Pol II.

Sohail Malik, Bing Ren, Ulrich Wagner, 2012, Molecular cell.

Efficient reconstitution of transcription elongation complexes for single-molecule studies of eukaryotic RNA polymerase II

Steven M Block, Robert Landick, A. Gnatt, 2012, Transcription.

RNA POLYMERASE II ELONGATION COMPLEX

P. Cramer, A. Gnatt, R. Kornberg, 2001 .

Evidence for a mediator cycle at the initiation of transcription.

A. Gnatt, R. Kornberg, Y. Li, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Regulation of RUNX2 transcription factor–DNA interactions and cell proliferation by vitamin D3 (cholecalciferol) prohormone activity

A. Passaniti, A. Gnatt, A. MacKerell, 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Structure-function relationship studies in human cholinesterases reveal genomic origins for individual variations in cholinergic drug responses

A. Gnatt, H. Soreq, H. Zakut, 1993, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Repeated tertiary fold of RNA polymerase II and implications for DNA binding.

M. Gerstein, D. Bushnell, A. Gnatt, 1998, Journal of molecular biology.

Molecular dissection of functional domains in human cholinesterases

A. Gnatt, 1992, Neurochemistry International.

Anionic site interactions in human butyrylcholinesterase disrupted by two single point mutations.

A. Gnatt, H. Soreq, S. Seidman, 1990, The Journal of biological chemistry.

Regulation of mammalian transcription by Gdown1 through a novel steric crosstalk revealed by cryo‐EM

A. Gnatt, Wei-Hau Chang, Xiaopeng Hu, 2012, The EMBO journal.

Article Transcriptional Regulation by Pol Ii(g) Involving Mediator and Competitive Interactions of Gdown1 and Tfiif with Pol Ii

B. Chait, B. Ren, Ulrich Wagner, 2022 .

Structural Basis of Transcription: An RNA Polymerase II Elongation Complex at 3.3 Å Resolution

P. Cramer, D. Bushnell, A. Gnatt, 2001, Science.

Structure-function relationship studies in human cholinesterases reveal genomic origins for individual variations in cholinergic drug responses

A. Gnatt, H. Soreq, H. Zakut, 1993, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Testicular amplification and impaired transmission of human butyrylcholinesterase cDNA in transgenic mice.

A. Gnatt, H. Soreq, M. Shani, 1994, Human reproduction.

Chimeric human cholinesterase. Identification of interaction sites responsible for recognition of acetyl- or butyrylcholinesterase-specific ligands.

A. Gnatt, H. Soreq, L. Neville, 1993, Journal of molecular biology.

Transcriptional regulation by Pol II(G) involving mediator and competitive interactions of Gdown1 and TFIIF with Pol II.

A. Gnatt, S. Malik, M. Jishage, 2012, Molecular cell.