J. Szostak

发表

Synthesizing life : Paths to unforeseeable science & technology

D. Bartel, P. Luisi, J. Szostak, 2001 .

Synthesizing life

D. Bartel, P. Luisi, J. Szostak, 2001, Nature.

Functional proteins from a random-sequence library

Anthony D. Keefe, J. Szostak, A. Keefe, 2001, Nature.

Is there left-handed DNA at the ends of yeast chromosomes?

J. Szostak, R. Walmsley, T. Petes, 1983, Nature.

Phylogenetic and genetic evidence for base-triples in the catalytic domain of group I introns

J. Szostak, A. Ellington, F. Michel, 1990, Nature.

In vitro selection of RNA molecules that bind specific ligands

J. Szostak, A. Ellington, 1990, Nature.

Functional information and the emergence of biocomplexity

Patrick L. Griffin, J. Szostak, R. Hazen, 2007, Proceedings of the National Academy of Sciences.

A DNA metalloenzyme with DNA ligase activity

J. Szostak, B. Cuenoud, 1995, Nature.

In vitro selection of functional nucleic acids.

J. Szostak, D. Wilson, David S. Wilson, 1999, Annual review of biochemistry.

Structural conventions for group I introns.

H. Tabak, M. Belfort, J. Szostak, 1987, Nucleic acids research.

Chromosome length controls mitotic chromosome segregation in yeast

A. Murray, J. Szostak, N. Schultes, 1986, Cell.

Isolation of new ribozymes from a large pool of random sequences [see comment].

D. Bartel, J. Szostak, 1993, Science.

RNA Catalysis in Model Protocell Vesicles

J. Szostak, I. Chen, K. Salehi-Ashtiani, 2005, Journal of the American Chemical Society.

3 Protocells: Genetic Polymers Inside Membrane Vesicles

J. Szostak, I. Chen, M. Hanczyc, 2006 .

Template-directed synthesis of a genetic polymer in a model protocell

J. Szostak, S. Mansy, Jason P. Schrum, 2008, Nature.

Coupled Growth and Division of Model Protocell Membranes

J. Szostak, Ting F. Zhu, 2009, Journal of the American Chemical Society.

Physical effects underlying the transition from primitive to modern cell membranes

J. Szostak, I. Budin, 2011, Proceedings of the National Academy of Sciences.

Concentration-Driven Growth of Model Protocell Membranes

J. Szostak, I. Budin, Anik Debnath, 2012, Journal of the American Chemical Society.

Nonenzymatic Template-Directed RNA Synthesis Inside Model Protocells

Katarzyna P. Adamala, J. Szostak, K. Adamala, 2013, Science.

Selection in vitro of single-stranded DNA molecules that fold into specific ligand-binding structures

J. Szostak, A. Ellington, 1992, Nature.

Unequal crossing over in the ribosomal DNA of Saccharomyces cerevisiae

J. Szostak, R. Wu, 1980, Nature.

A DNA aptamer that binds adenosine and ATP.

J. Szostak, D. Huizenga, Jack W. Szostak, 1995, Biochemistry.

Isolation of a fluorophore-specific DNA aptamer with weak redox activity.

J. Szostak, C. Wilson, 1998, Chemistry & biology.

Isolation of high-affinity GTP aptamers from partially structured RNA libraries

J. Szostak, Jonathan H. Davis, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Attempts to Define Life Do Not Help to Understand the Origin of Life

J. Szostak, 2012, Journal of biomolecular structure & dynamics.

RNA-peptide fusions for the in vitro selection of peptides and proteins.

J W Szostak, J. Szostak, R. Roberts, 1997, Proceedings of the National Academy of Sciences of the United States of America.

In vitro evolution of new ribozymes with polynucleotide kinase activity

Jon R. Lorsch, Jack W. Szostak, J. Szostak, 1994, Nature.

Selection and evolution of enzymes from a partially randomized non-catalytic scaffold

Burckhard Seelig, Jack W. Szostak, J. Szostak, 2007, Nature.

Synthesis of phosphoramidate-linked DNA by a modified DNA polymerase

J. Szostak, V. Lelyveld, Wen Zhang, 2020, Proceedings of the National Academy of Sciences.

Origin of life on earth.

J. Szostak, A. Ricardo, Jack W Szostak, 2009, Scientific American.

The double-strand-break repair model for recombination

Jack W. Szostak, J. Szostak, R. Rothstein, 1983, Cell.

In Vitro Selection of Functional Oligonucleotides and the Origins of Biochemical Activity

J. Szostak, J. Carothers, 2006 .

The guanosine binding site of the Tetrahymena ribozyme

François Michel, David P. Bartel, Jack W. Szostak, 1989, Nature.

The use of mRNA display to select high-affinity protein-binding peptides

Anthony D. Keefe, J W Szostak, J. Szostak, 2001, Proceedings of the National Academy of Sciences of the United States of America.

A strategy for the generation of conditional mutations by protein destabilization.

J. Szostak, D. Finley, E. Park, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Artificial lantipeptides from in vitro translations.

J. Szostak, A. Ricardo, F. Seebeck, 2011, Chemical communications.

Protocells Nonenzymatic Template-Directed RNA Synthesis Inside Model

J. Szostak, K. Adamala, 2013 .

The eightfold path to non-enzymatic RNA replication

Jack W. Szostak, J. Szostak, 2012 .

An RNA motif that binds ATP

Jack W. Szostak, J. Szostak, M. Sassanfar, 1993, Nature.

RNA-catalysed synthesis of complementary-strand RNA

Jennifer A. Doudna, Jack W. Szostak, J. Doudna, 1989, Nature.

Solution structure of an informationally complex high-affinity RNA aptamer to GTP.

James M Carothers, J. Szostak, J. Chou, 2006, RNA.

aptamer to GTP Solution structure of an informationally complex high-affinity RNA

J. Szostak, J. Chou, J. Carothers, 2006 .

Aptamers selected for higher-affinity binding are not more specific for the target ligand.

J. Szostak, J. Carothers, S. Oestreich, 2006, Journal of the American Chemical Society.

Informational Complexity and Functional Activity of RNA Structures

James M. Carothers, Jack W. Szostak, J. Szostak, 2004, Journal of the American Chemical Society.

An in Vitro Selection System for TNA

J. Szostak, Biao Yu, L. McLaughlin, 2005, Journal of the American Chemical Society.

Insertion of a genetic marker into the ribosomal DNA of yeast.

J. Szostak, R. Wu, R. Wu, 1979, Plasmid.

Ribosomal Synthesis of N-Methyl Peptides

J. Szostak, Alexander O. Subtelny, Matthew C. T. Hartman, 2008, Journal of the American Chemical Society.

Construction and behavior of circularly permuted and telocentric chromosomes in Saccharomyces cerevisiae

A. Murray, J. Szostak, 1986, Molecular and cellular biology.

Construction and behavior of circularly permuted and telocentric chromosomes in Saccharomyces cerevisiae

A. Murray, J. Szostak, 1986 .

Synthesis of RNA containing inosine: analysis of the sequence requirements for the 5' splice site of the Tetrahymena group I intron.

S. Benner, A. Rich, R. Green, 1991, Nucleic acids research.

Competition between bridged dinucleotides and activated mononucleotides determines the error frequency of nonenzymatic RNA primer extension

J. Szostak, C. Carr, T. Walton, 2021, bioRxiv.

Assembly of a functional ribozyme from short oligomers by enhanced non-enzymatic ligation

J. Szostak, D. O’Flaherty, Lijun Zhou, 2019, bioRxiv.

Efficient and Rapid Template-Directed Nucleic Acid Copying Using 2′-Amino-2′,3′-dideoxyribonucleoside−5′-Phosphorimidazolide Monomers

J. Szostak, A. Ricardo, Jason P. Schrum, 2009, Journal of the American Chemical Society.

Copying of Mixed-Sequence RNA Templates inside Model Protocells

J. Szostak, Neha P. Kamat, N. Prywes, 2018, Journal of the American Chemical Society.

Constructing high complexity synthetic libraries of long ORFs using in vitro selection.

J. Szostak, A. Keefe, D. Wilson, 2000, Journal of molecular biology.

ARD1 and NAT1 proteins form a complex that has N‐terminal acetyltransferase activity.

J. Szostak, E. Park, E. Park, 1992, The EMBO journal.

The ARD1 gene of yeast functions in the switch between the mitotic cell cycle and alternative developmental pathways

J. Szostak, M. Whiteway, 1985, Cell.

Identification of healed terminal DNA fragments in linear minichromosomes of Schizosaccharomyces pombe

J. Szostak, O. Niwa, M. Yanagida, 1987 .

UV-light-driven prebiotic synthesis of iron-sulfur clusters.

J. Szostak, D. Sasselov, S. Mansy, 2017, Nature chemistry.

Cloning regulated yeast genes from a pool of lacZ fusions.

A. Murray, J. Szostak, S. Ruby, 1983, Methods in enzymology.

Specific Saccharomyces cerevisiae genes are expressed in response to DNA-damaging agents

J. Szostak, S. Ruby, 1985, Molecular and cellular biology.

A rapid procedure for the construction of linear yeast plasmids.

J. Szostak, 1983, Methods in enzymology.

Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide

Seung Soo Oh, J. Szostak, Wen Zhang, 2018, Journal of the American Chemical Society.

Telomeric repeat from T. thermophila cross hybridizes with human telomeres

S. Cross, J. Szostak, R. Allshire, 1988, Nature.

The Yeast ARD] Gene Product Is Required for Repression of Cryptic Mating-Type Information at the HML Locust

J. Thorner, J. Szostak, M. Whiteway, 2014 .

Meiotic recombination on artificial chromosomes in yeast.

A. Nicolas, J. Szostak, L. Ross, 1992, Genetics.

A strategy forthegeneration ofconditional mutations byprotein destabilization

J. Szostak, 1992 .

Genetic and physical analyses of sister chromatid exchange in yeast meiosis

J. Szostak, D. Dawson, H. Sun, 1991, Molecular and cellular biology.

Genetic andPhysical Analyses ofSister Chromatid Exchange inYeastMeiosis

J. Szostak, D. Dawson, Hong Sun, 1991 .

Characterization of two telomeric DNA processing reactions in Saccharomyces cerevisiae

A. Murray, J. Szostak, T. E. Claus, 1988, Molecular and Cellular Biology.

Roles of the 2 microns gene products in stable maintenance of the 2 microns plasmid of Saccharomyces cerevisiae

A. Murray, J. Szostak, A. Reynolds, 1987, Molecular and cellular biology.

[17] Construction of specific chromosomal rearrangements in yeast

J. Szostak, N. Sugawara, 1983 .

[18] Yeast vectors with negative selection

J. Szostak, P. A. Brown, 1983 .

Chromosome segregation in mitosis and meiosis.

A. Murray, J. Szostak, A. Murray, 1985, Annual review of cell biology.

Fungal recombination

J. Szostak, T. Orr-Weaver, 1985 .

Decreasing gradients of gene conversion on both sides of the initiation site for meiotic recombination at the ARG4 locus in yeast.

J. Szostak, N. Schultes, 1990, Genetics.

Hybridization with synthetic oligonucleotides.

J. Szostak, B. Tye, F. Sherman, 1979, Methods in enzymology.

In vitro selection and directed evolution.

J. Szostak, 1997, Harvey lectures.

Gene conversion adjacent to regions of double-strand break repair

A. Nicolas, J. Szostak, T. Orr-Weaver, 1988, Molecular and cellular biology.

Shrink-wrap vesicles.

J. Szostak, I. Chen, Shelly M Fujikawa, 2005, Langmuir : the ACS journal of surfaces and colloids.

Transfer of Sequence Information and Replication of Diimine Duplexes

J. Szostak, N. Prywes, Kyle R Strom, 2019, The Journal of organic chemistry.

In vitro selection of ribozyme ligases that use prebiotically plausible 2-aminoimidazole–activated substrates

Seung Soo Oh, J. Szostak, Saurja DasGupta, 2020, Proceedings of the National Academy of Sciences.

Selection of cyclic peptide aptamers to HCV IRES RNA using mRNA display

J. Szostak, A. Litovchick, 2008, Proceedings of the National Academy of Sciences.

Uncovering the Thermodynamics of Monomer Binding for RNA Replication

J. Szostak, Wen Zhang, N. Zhang, 2015, Journal of the American Chemical Society.

Telomeres and Telomerase in Cellular Aging ( Senescence ) [ 1 ]

J. Szostak, 2019 .

Telomeres and Telomerase in Cellular Aging (Senescence)

J. Szostak, 2017 .

Vesicle extrusion through polycarbonate track-etched membranes using a hand-held mini-extruder.

J. Szostak, Ting F. Zhu, I. Budin, 2013, Methods in enzymology.

Multiple, Tandem Plasmid Integration in Saccharomyces cerevisiae

J. Szostak, T. Orr-Weaver, Terry L. Orr-Weaver, 1983, Molecular and cellular biology.

Hybridization kinetics of out-of-equilibrium mixtures of short RNA oligonucleotides

J. Szostak, M. Todisco, 2022, bioRxiv.

Replication and resolution of telomeres in yeast.

J. Szostak, 1983, Cold Spring Harbor symposia on quantitative biology.

Ribozyme catalysis

J. Szostak, Charles Wilson, 1992, Current Biology.

Specific binding of a synthetic oligodeoxyribonucleotide to yeast cytochrome c mRNA

J. Szostak, J. Stiles, C. Bahl, 1977, Nature.

A strategy for the generation of conditional mutations by protein destabilization.

J. Szostak, D. Finley, E. Park, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Glycerol nucleoside triphosphates: synthesis and polymerase substrate activities.

J. Szostak, L. McLaughlin, Allen T. Horhota, 2006, Organic letters.

Shielding from UV Photodamage: Implications for Surficial Origins of Life Chemistry on the Early Earth

Zoe R. Todd, J. Szostak, D. Sasselov, 2021, ACS earth & space chemistry.

Ultraviolet-Driven Deamination of Cytidine Ribonucleotides Under Planetary Conditions

Zoe R. Todd, J. Szostak, D. Sasselov, 2020, Astrobiology.

UV photostability of three 2-aminoazoles with key roles in prebiotic chemistry on the early earth

Zoe R. Todd, J. Szostak, D. Sasselov, 2019, Chemical communications.

The ascent of molecules.

J. Szostak, A. Engelhart, M. Powner, 2013, Nature chemistry.

Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging

E. Blackburn, J. Szostak, C. Greider, 2006, Nature Medicine.

The Hayflick Limit

J. Szostak, C. Greider, A. Olovnikov, 2017 .

GeneConversion Adjacent toRegions ofDouble-Strand BreakRepair

J. Szostak, T. Orr-Weaver, 1988 .

Mineral Surface Directed Membrane Assembly

J. Szostak, S. Mansy, M. Hanczyc, 2007, Origins of Life and Evolution of Biospheres.

Carol Widney Greider (1961-)

J. Szostak, C. Greider, Carol Widney, 2019 .

Unusual metal ion catalysis in an acyl-transferase ribozyme.

J. Szostak, H. Suga, J. Cowan, 1998, Biochemistry.

Roles of the 2 , um Gene Products in Stable Maintenance of the 2 iim Plasmid of Saccharomyces cerevisiae

A. Murray, J. Szostak, A. Reynolds, 2022 .

A kinetic study of the growth of fatty acid vesicles.

Irene A Chen, J. Szostak, I. Chen, 2004, Biophysical journal.

Membrane growth can generate a transmembrane pH gradient in fatty acid vesicles.

J. Szostak, I. Chen, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Lipid constituents of model protocell membranes.

J. Szostak, Anna Wang, 2019, Emerging topics in life sciences.

Thermostability of model protocell membranes

J. Szostak, S. Mansy, Jack W Szostak, 2008, Proceedings of the National Academy of Sciences.

PRELIMINARY COMMUNICATION Open Access

J. Szostak, Ting F. Zhu, 2011 .

Chemoselective Multicomponent One-Pot Assembly of Purine Precursors in Water

J. Szostak, J. Sutherland, M. Powner, 2010, Journal of the American Chemical Society.

Introduction: Combinatorial Chemistry.

Jack W. Szostak, J. Szostak, 1997, Chemical reviews.

A Small Aptamer with Strong and Specific Recognition of the Triphosphate of ATP

Jack W. Szostak, J. Szostak, P. Sazani, 2004, Journal of the American Chemical Society.

Synthesis and Nonenzymatic Template-Directed Polymerization of 2′-Amino-2′-deoxythreose Nucleotides

Jack W. Szostak, J. Szostak, A. Ricardo, 2014, Journal of the American Chemical Society.

In vitro evolution of a self-alkylatlng ribozyme

Jack W. Szostak, J. Szostak, Charles Wilson, 1995, Nature.

Folding and Duplex Formation in Sequence-Defined Aniline Benzaldehyde Oligoarylacetylenes

J. Szostak, Kyle R Strom, 2022, Journal of the American Chemical Society.

Chance and necessity in the selection of nucleic acid catalysts.

J R Lorsch, J W Szostak, J. Szostak, 1996, Accounts of chemical research.

Solid-Phase Synthesis of Sequence-Defined Informational Oligomers

J. Szostak, Kyle R Strom, Kyle R. Strom, 2020, The Journal of organic chemistry.

Template‐Directed Copying of RNA by Non‐enzymatic Ligation†

J. Szostak, D. O’Flaherty, Lijun Zhou, 2020, Angewandte Chemie.

The Narrow Road to the Deep Past: In Search of the Chemistry of the Origin of Life.

J. Szostak, Jack W Szostak, 2017, Angewandte Chemie.

Enhanced Nonenzymatic RNA Copying with 2-Aminoimidazole Activated Nucleotides

Victor S Lelyveld, J. Szostak, V. Lelyveld, 2017, Journal of the American Chemical Society.

An Expanded Set of Amino Acid Analogs for the Ribosomal Translation of Unnatural Peptides

Jack W. Szostak, J. Szostak, Chi-Wang Lin, 2007, PloS one.

mRNA display: from basic principles to macrocycle drug discovery.

J. Szostak, A. Ricardo, Jack W Szostak, 2014, Drug discovery today.

In Vitro Selection of Highly Modified Cyclic Peptides That Act as Tight Binding Inhibitors

J. Szostak, Matthew C. T. Hartman, K. Josephson, 2012, Journal of the American Chemical Society.

Ribosomal synthesis of unnatural peptides.

J. Szostak, Matthew C. T. Hartman, K. Josephson, 2005, Journal of the American Chemical Society.

Stereospecific recognition of tryptophan agarose by in vitro selected RNA

Michael Famulok, Jack W. Szostak, J. Szostak, 1992 .

Competition between model protocells driven by an encapsulated catalyst.

Katarzyna P. Adamala, Katarzyna Adamala, J. Szostak, 2013, Nature chemistry.

The Origin of Life on Earth and the Design of Alternative Life Forms

J. Szostak, 2017, The Promise of Science.

Ribozyme-catalyzed tRNA aminoacylation

Y. Bessho, J. Szostak, N. Lee, 2000, Nature Structural Biology.

Deep Phylogeny

Randall, J. Szostak, Ting F. Zhu, 2010 .

Evidence that the guanosine substrate of the Tetrahymena ribozyme is bound in the anti conformation and that N7 contributes to binding.

J. Szostak, M. Hanna, C. W. Lin, 1994, Biochemistry.

Fast and accurate nonenzymatic copying of an RNA-like synthetic genetic polymer

J. Szostak, S. Gryaznov, D. Zielińska, 2013, Proceedings of the National Academy of Sciences.

Synthesis of N3′-P5′-linked Phosphoramidate DNA by Nonenzymatic Template-Directed Primer Extension

J. Szostak, N. Zhang, J. C. Blain, 2012, Journal of the American Chemical Society.

Chemical synthesis of oligoribonucleotides containing 2-aminopurine: substrates for the investigation of ribozyme function.

A. Rich, J. Doudna, J. Szostak, 1990, The Journal of organic chemistry.

Ribosomal synthesis of dehydroalanine-containing peptides.

J. Szostak, F. Seebeck, 2006, Journal of the American Chemical Society.

Enzymatic aminoacylation of tRNA with unnatural amino acids.

J. Szostak, Matthew C. T. Hartman, K. Josephson, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Structural and kinetic characterization of an acyl transferase ribozyme.

J. Szostak, P. Lohse, H. Suga, 1998, Journal of the American Chemical Society.

Ribozymes: aiming at RNA replication and protein synthesis.

J W Szostak, A J Hager, J. Szostak, 1996, Chemistry & biology.

Ribozyme-catalysed amino-acid transfer reactions

J. Szostak, P. Lohse, 1996, Nature.

Nucleic acid crystallization and X-ray crystallography facilitated by single selenium atom

J. Szostak, Wen Zhang, Zhen Huang, 2016, Frontiers of Chemical Science and Engineering.

Point mutations in the yeast histone H4 gene prevent silencing of the silent mating type locus HML

J. Szostak, E. Park, 1990 .

Point mutations in the yeast histone H4 gene prevent silencing of the silent mating type locus HML.

J. Szostak, E. Park, Jack W. Szostak, 1990, Molecular and cellular biology.

Unusual Base-Pairing Interactions in Monomer–Template Complexes

J. Szostak, Wen Zhang, Jiawei Wang, 2016, ACS central science.

RNA conformation and metal ion coordination in the nonenzymatic primer extension reaction center

J. Szostak, S. Mittal, Collin R. Nisler, 2023, bioRxiv.

Protocells and RNA Self-Replication.

G. F. Joyce, J. Szostak, Jack W Szostak, 2018, Cold Spring Harbor perspectives in biology.

HIV-1 rev regulation involves recognition of non-Watson-Crick base pairs in viral RNA

Michael R. Green, D. Bartel, J. Szostak, 1991, Cell.

The yeast ARD1 gene product is required for repression of cryptic mating-type information at the HML locus

J. Thorner, J. Szostak, M. Whiteway, 1987, Molecular and cellular biology.

Downstream Oligonucleotides Strongly Enhance the Affinity of GMP to RNA Primer–Template Complexes

J. Szostak, N. Prywes, A. Fahrenbach, 2017, Journal of the American Chemical Society.

Yeast transformation: a model system for the study of recombination.

J W Szostak, J. Szostak, R. Rothstein, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Crystal Structure Studies of RNA Duplexes Containing s2U:A and s2U:U Base Pairs

J. Szostak, Aaron T. Larsen, Benjamin D. Heuberger, 2014, Journal of the American Chemical Society.

Origins of life: Systems chemistry on early Earth

J. Szostak, Jack W. Szostak, 2009, Nature.

An initiation site for meiotic gene conversion in the yeast Saccharomyces cerevisiae

A. Nicolas, J. Szostak, N. Schultes, 1989, Nature.

One-step purification of recombinant proteins using a nanomolar-affinity streptavidin-binding peptide, the SBP-Tag.

Anthony D. Keefe, J. Szostak, A. Keefe, 2001, Protein expression and purification.

Photochemically driven redox chemistry induces protocell membrane pearling and division

Katarzyna P. Adamala, J. Szostak, N. Zhang, 2012, Proceedings of the National Academy of Sciences.

RNA aptamers that bind flavin and nicotinamide redox cofactors.

J W Szostak, J. Szostak, C T Lauhon, 1995, Journal of the American Chemical Society.

Collaboration between primitive cell membranes and soluble catalysts

Katarzyna P. Adamala, J. Szostak, A. Engelhart, 2016, Nature Communications.

A simple physical mechanism enables homeostasis in primitive cells

Katarzyna P Adamala, Katarzyna P. Adamala, J. Szostak, 2016, Nature chemistry.

Rapid RNA Exchange in Aqueous Two-Phase System and Coacervate Droplets

Tony Z. Jia, J. Szostak, Christian Hentrich, 2014, Origins of Life and Evolution of Biospheres.

In vitro evolution suggests multiple origins for the hammerhead ribozyme

Jack W. Szostak, J. Szostak, K. Salehi-Ashtiani, 2001, Nature.

2',3'-Dideoxy-3'-thionucleoside triphosphates: syntheses and polymerase substrate activities.

J. Szostak, L. McLaughlin, Meena, 2007, Organic letters.

Cloning yeast telomeres on linear plasmid vectors

Jack W. Szostak, E. Blackburn, J. Szostak, 1982, Cell.

Enzymatic activity of the conserved core of a group I self-splicing intron

J. Szostak, 1986, Nature.

Bidirectional Direct Sequencing of Noncanonical RNA by Two-Dimensional Analysis of Mass Chromatograms

J. Szostak, V. Lelyveld, J. C. Blain, 2015, Journal of the American Chemical Society.

Oligoarginine Peptides Slow Strand Annealing and Assist Nonenzymatic RNA Replication

Katarzyna P. Adamala, Tony Z. Jia, J. Szostak, 2016, Nature chemistry.

Evolution of functional nucleic acids in the presence of nonheritable backbone heterogeneity

J. Szostak, N. Zhang, Simon G. Trevino, 2011, Proceedings of the National Academy of Sciences.

Single-molecule binding experiments on long time scales.

Antoine M van Oijen, J. Szostak, A. V. van Oijen, 2010, The Review of scientific instruments.

Single-Molecule Imaging of an in Vitro-Evolved RNA Aptamer Reveals Homogeneous Ligand Binding Kinetics

J. Szostak, A. V. van Oijen, Mark P. Elenko, 2009, Journal of the American Chemical Society.

Divergent prebiotic synthesis of pyrimidine and 8-oxo-purine ribonucleotides

Dejan-Krešimir Bučar, Shao-Liang Zheng, J. Szostak, 2017, Nature Communications.

Effect of terminal 3'-hydroxymethyl modification of an RNA primer on nonenzymatic primer extension.

J. Szostak, A. Pal, L. McLaughlin, 2016, Chemical Communications.

Expanding the structural and functional diversity of RNA: analog uridine triphosphates as candidates for in vitro selection of nucleic acids.

J. Szostak, N. Vaish, L. McLaughlin, 2000, Nucleic acids research.

Enzymatic synthesis of DNA on glycerol nucleic acid templates without stable duplex formation between product and template

J. Szostak, Jack W Szostak, Ching-Hsuan Tsai, 2007, Proceedings of the National Academy of Sciences.

The Free Energy Landscape of Pseudorotation in 3′–5′ and 2′–5′ Linked Nucleic Acids

J. Szostak, Li Li, 2014, Journal of the American Chemical Society.

Stereochemical course of catalysis by the Tetrahymena ribozyme.

J. Doudna, J. Szostak, J. Rajagopal, 1989, Science.

A novel, modification-dependent ATP-binding aptamer selected from an RNA library incorporating a cationic functionality.

J. Szostak, N. Vaish, L. McLaughlin, 2003, Biochemistry.

Thiolated uridine substrates and templates improve the rate and fidelity of ribozyme-catalyzed RNA copying.

Seung Soo Oh, Yale S Michaels, J. Szostak, 2016, Chemical communications.

Replacing Uridine with 2-Thiouridine Enhances the Rate and Fidelity of Nonenzymatic RNA Primer Extension

Jack W. Szostak, J. Szostak, V. Topkar, 2015, Journal of the American Chemical Society.

Activated Ribonucleotides Undergo a Sugar Pucker Switch upon Binding to a Single-Stranded RNA Template

Na Zhang, Jack W. Szostak, J. Szostak, 2012, Journal of the American Chemical Society.

Kinetic and mechanistic analysis of nonenzymatic, template-directed oligoribonucleotide ligation.

J W Szostak, D. Bartel, J. Szostak, 1996, Journal of the American Chemical Society.

Progress toward synthetic cells.

J. Szostak, Jack W Szostak, J Craig Blain, 2014, Annual review of biochemistry.

5 Efficient and high-fidelity copying of an RNA-like model prebiotic system

J. Szostak, S. Gryaznov, Shenglong Zhang, 2013 .

4 Towards non-enzymatic RNA replication

J. Szostak, 2013 .

A Mechanistic Explanation for the Regioselectivity of Nonenzymatic RNA Primer Extension

Jack W. Szostak, Li Li, J. Szostak, 2017, Journal of the American Chemical Society.

Thermodynamic insights into 2-thiouridine-enhanced RNA hybridization

Jia Sheng, Jack W. Szostak, Albert C. Fahrenbach, 2015, Nucleic acids research.

A Potential Role for Aminoacylation in Primordial RNA Copying Chemistry

J. Szostak, V. Lelyveld, A. Radaković, 2020, bioRxiv.

A Model for the Emergence of RNA from a Prebiotically Plausible Mixture of Ribonucleotides, Arabinonucleotides, and 2′-Deoxynucleotides

J. Szostak, Wen Zhang, S. Kim, 2020, Journal of the American Chemical Society.

A model for the emergence of RNA from a prebiotically plausible mixture of ribonucleotides, arabinonucleotides and 2’-deoxynucleotides

J. Szostak, Wen Zhang, S. Kim, 2019, bioRxiv.

Functional RNAs exhibit tolerance for non-heritable 2'-5' versus 3'-5' backbone heterogeneity.

J. Szostak, A. Engelhart, Jack W Szostak, 2013, Nature chemistry.

Functional RNAs exhibit tolerance for non-heritable 2 9 – 5 9 versus 3 9 – 5 9 backbone heterogeneity

J. Szostak, A. Engelhart, M. Powner, 2013 .

High fidelity TNA synthesis by Therminator polymerase

Larry W. McLaughlin, Allen Horhota, Jack W. Szostak, 2005, Nucleic acids research.

Structure and Activity of Ribozymes

J. Szostak, 1988 .

N2′→P3′ Phosphoramidate Glycerol Nucleic Acid as a Potential Alternative Genetic System

J. Szostak, Xin Cai, Jesse J. Chen, 2009, Journal of the American Chemical Society.

Kinetic Analysis of an Efficient DNA-Dependent TNA Polymerase

J. Szostak, J. Chaput, Biao Yu, 2005, Journal of the American Chemical Society.

In vitro selection of RNA aptamers specific for cyanocobalamin.

J. Szostak, J. Lorsch, 1994, Biochemistry.

TNA synthesis by DNA polymerases.

J. Szostak, J. Chaput, 2003, Journal of the American Chemical Society.

Extensive 3′-overhanging, single-stranded DNA associated with the meiosis-specific double-strand breaks at the ARG4 recombination initiation site

J. Szostak, D. Treco, Hong Sun, 1991, Cell.

Detection of heteroduplex DNA molecules among the products of Saccharomyces cerevisiae meiosis.

J W Szostak, A. Nicolas, J. Szostak, 1990, Proceedings of the National Academy of Sciences of the United States of America.

S-phase Enriched Non-coding RNAs Regulate Gene Expression and Cell Cycle Progression.

R. Kingston, J. Szostak, R. Sadreyev, 2020, Cell reports.

Mettl1/Wdr4-Mediated m7G tRNA Methylome Is Required for Normal mRNA Translation and Embryonic Stem Cell Self-Renewal and Differentiation.

Victor S Lelyveld, Qi Liu, J. Szostak, 2018, Molecular cell.

Multicomponent Assembly of Proposed DNA Precursors in Water

J. Szostak, M. Powner, Shao-Liang Zheng, 2012, Journal of the American Chemical Society.

Experimental Models of Primitive Cellular Compartments: Encapsulation, Growth, and Division

Martin M. Hanczyc, Jack W. Szostak, J. Szostak, 2003, Science.

Recombination between sequences in nonhomologous positions.

J. Szostak, N. Sugawara, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Pinpointing RNA-Protein Cross-Links with Site-Specific Stable Isotope-Labeled Oligonucleotides

J. Szostak, V. Lelyveld, Elizabeth Ransey, 2015, Journal of the American Chemical Society.

Yeast recombination: the association between double-strand gap repair and crossing-over.

J. Szostak, T. Orr-Weaver, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Evolutionary optimization of a nonbiological ATP binding protein for improved folding stability.

John C Chaput, J. Szostak, J. Chaput, 2004, Chemistry & biology.

A poly(dA.dT) tract is a component of the recombination initiation site at the ARG4 locus in Saccharomyces cerevisiae

J W Szostak, J. Szostak, N. Schultes, 1991, Molecular and cellular biology.

Bacterial carotenoids suppress Caenorhabditis elegans surveillance and defense of translational dysfunction

G. Ruvkun, J. Szostak, V. Lelyveld, 2020, bioRxiv.

A mutant with a defect in telomere elongation leads to senescence in yeast

J. Szostak, V. Lundblad, 1989, Cell.

Transfer of yeast telomeres to linear plasmids by recombination

J. Szostak, B. Dunn, M. Pardue, 1984, Cell.

Controlled Growth of Filamentous Fatty Acid Vesicles under Flow

J. Szostak, Christian Hentrich, 2014, Langmuir : the ACS journal of surfaces and colloids.

DNA sequences of telomeres maintained in yeast

Jack W. Szostak, E. Blackburn, J. Szostak, 1984, Nature.

The beginning of the ends

J. Szostak, 1989, Nature.

Genetic applications of yeast transformation with linear and gapped plasmids.

J W Szostak, J. Szostak, R. Rothstein, 1983, Methods in enzymology.

Fatty Acid/Phospholipid Blended Membranes: A Potential Intermediate State in Protocellular Evolution.

Siddhartha G. Jena, J. Szostak, Neha P. Kamat, 2018, Small.

Exploding vesicles

J. Szostak, Ting F. Zhu, 2011 .

Structural insights into the effects of 2′-5′ linkages on the RNA duplex

Li Li, Jia Sheng, J. Szostak, 2014, Proceedings of the National Academy of Sciences.

Template‐Directed Copying of RNA by Non‐enzymatic Ligation

J. Szostak, D. O’Flaherty, Lijun Zhou, 2020, Angewandte Chemie.

Prebiotically Plausible “Patching” of RNA Backbone Cleavage through a 3′–5′ Pyrophosphate Linkage

J. Szostak, Wen Zhang, A. Radaković, 2019, Journal of the American Chemical Society.

Prebiotically Plausible ‘Patching’ of RNA Backbone Cleavage Through a 3′-5′ Pyrophosphate Linkage

Jack W. Szostak, J. Szostak, A. Radaković, 2019, bioRxiv.

The origins of cellular life.

J. Szostak, Jason P. Schrum, Ting F. Zhu, 2010, Cold Spring Harbor perspectives in biology.

Expanding roles for diverse physical phenomena during the origin of life.

J. Szostak, I. Budin, Jack W Szostak, 2010, Annual review of biophysics.

Effect of Stalling after Mismatches on the Error Catastrophe in Nonenzymatic Nucleic Acid Replication

Martin A. Nowak, Irene A. Chen, Douglas A. Treco, 2010, Journal of the American Chemical Society.

The Origins of Cellular Life service

J. Szostak, Jason P. Schrum, Ting F. Zhu, 2010 .

Structurally complex and highly active RNA ligases derived from random RNA sequences.

J W Szostak, D. Bartel, J. Szostak, 1995, Science.

Selection of a ribozyme that functions as a superior template in a self-copying reaction.

J W Szostak, R. Green, J. Szostak, 1992, Science.

A multisubunit ribozyme that is a catalyst of and template for complementary strand RNA synthesis.

J. Doudna, J. Szostak, S. Couture, 1991, Science.

genetic analysis: Selection and amplification of rare functional nucleic acids

Andrew D. Ellington, David P. Bartel, Jack W. Szostak, 1991 .

Construction of artificial chromosomes in yeast

A. Murray, J. Szostak, A. Murray, 1983, Nature.

Reverse transcriptase reads through a 2'-5'linkage and a 2'-thiophosphate in a template.

J R Lorsch, J W Szostak, D. Bartel, 1995, Nucleic acids research.

An alternative pathway for meiotic chromosome segregation in yeast.

A. Murray, J. Szostak, D. Dawson, 1986, Science.

Template-Directed Nonenzymatic Primer Extension Using 2-Methylimidazole-Activated Morpholino Derivatives of Guanosine and Cytidine

J. Szostak, A. Ricardo, A. Pal, 2019, Journal of the American Chemical Society.

Isolation of a ribozyme with 5'-5' ligase activity.

J. Szostak, K. Chapman, 1995, Chemistry & biology.

A Genomewide Search for Ribozymes Reveals an HDV-Like Sequence in the Human CPEB3 Gene

Andrej Lupták, J. Szostak, K. Salehi-Ashtiani, 2006, Science.

Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex

J. Szostak, Wen Zhang, T. Walton, 2017, Proceedings of the National Academy of Sciences.

Nonenzymatic copying of RNA templates containing all four letters is catalyzed by activated oligonucleotides

J. Szostak, N. Prywes, Noam Prywes, 2016, eLife.

In search of the RNA world on Mars

M. Zuber, J. Szostak, J. Head, 2020, bioRxiv.

20 In Vitro Selection of Functional RNA Sequences

J. Szostak, A. Ellington, 1993 .

Chain-Length Heterogeneity Allows for the Assembly of Fatty Acid Vesicles in Dilute Solutions

Na Zhang, J. Szostak, N. Zhang, 2014, Biophysical journal.

Scanning the human proteome for calmodulin-binding proteins

J. Szostak, Xinchun Shen, Biao Dong, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Functional requirements for specific ligand recognition by a biotin-binding RNA pseudoknot.

J. Szostak, C. Wilson, Charles Wilson, 1998, Biochemistry.

Kinetic and thermodynamic characterization of the reaction catalyzed by a polynucleotide kinase ribozyme.

J. Szostak, J. Lorsch, 1995, Biochemistry.

The Emergence of Competition Between Model Protocells

Irene A. Chen, Jack W. Szostak, J. Szostak, 2004, Science.

Large phenotypic enhancement of structured random RNA pools.

J. Szostak, A. Lupták, Fabio Chizzolini, 2019, Journal of the American Chemical Society.

DNA polymerase activity on synthetic N3′→P5′ phosphoramidate DNA templates

Victor S Lelyveld, J. Szostak, V. Lelyveld, 2019, Nucleic acids research.

DNA ends: just the beginning (Nobel lecture).

J. Szostak, 2010, Angewandte Chemie.

DNA ENDS: JUST THE BEGINNING

J. Szostak, 2009 .

Pedigree analysis of plasmid segregation in yeast

A. Murray, J. Szostak, A. Murray, 1983, Cell.

Yeast vectors with negative selection.

J. Szostak, P. A. Brown, 1983, Methods in enzymology.

Generation of Functional RNAs from Inactive Oligonucleotide Complexes by Non-enzymatic Primer Extension

Katarzyna P. Adamala, J. Szostak, A. Engelhart, 2014, Journal of the American Chemical Society.

embryonic development to death , including the discovery of the effects of shortening repetitive sequences of DNA , called telomeres , on the ends of chromosomes

J. Szostak, C. Greider, A. Olovnikov, 2019 .

Identification of healed terminal DNA fragments in linear minichromosomes of Schizosaccharomyces pombe

J. Szostak, O. Niwa, M. Yanagida, 1987, Molecular and cellular biology.

Telomeres and artificial chromosomes in yeast

A. Murray, J. Szostak, B. Dunn, 1984 .

Optimized synthesis of RNA-protein fusions for in vitro protein selection.

J W Szostak, Jeffrey E. Barrick, J. Barrick, 2000, Methods in enzymology.

Metal-ion catalyzed polymerization in the eutectic phase in water-ice: a possible approach to template-directed RNA polymerization.

J. Szostak, P. Monnard, 2008, Journal of inorganic biochemistry.

In Vitro Selection of Specific Ligand‐binding Nucleic Acids

Michael Famulok, Jack W. Szostak, J. Szostak, 1992 .

Template-directed primer extension catalyzed by the Tetrahymena ribozyme.

D. Bartel, J. Doudna, J. Szostak, 1991, Molecular and cellular biology.

Common and Potentially Prebiotic Origin for Precursors of Nucleotide Synthesis and Activation

Masashi Aono, J. Szostak, M. Aono, 2017, Journal of the American Chemical Society.

Reconstructing the emergence of cellular life through the synthesis of model protocells.

J W Szostak, J. Szostak, S. Mansy, 2009, Cold Spring Harbor symposia on quantitative biology.

Non-enzymatic primer extension with strand displacement

Jack W. Szostak, J. Szostak, Derek K. O’Flaherty, 2019, bioRxiv.

Non-enzymatic primer extension with strand displacement 1

Giurgiu, J. Szostak, T. H. Wright, 2022 .

Flip-flop-induced relaxation of bending energy: implications for membrane remodeling.

J. Szostak, L. Mahadevan, R. Bruckner, 2009, Biophysical Journal.

In vitro genetic analysis of the hinge region between helical elements P5-P4-P6 and P7-P3-P8 in the sunY group I self-splicing intron.

R. Green, J. Szostak, 1994, Journal of molecular biology.

In vitro selection of RNA aptamers against a composite small molecule-protein surface

James M. Carothers, Gregory L. Verdine, Masahiro Yoshimura, 2005, Nucleic acids research.

Molecular biology: RNA gets a grip on translation

J. Szostak, 2002, Nature.

Deep sequencing of non-enzymatic RNA primer extension

Christopher E. Carr, Jack W. Szostak, Daniel Duzdevich, 2020, bioRxiv.

Ribose Alters the Photochemical Properties of the Nucleobase in Thionated Nucleosides

J. Szostak, D. Sasselov, J. Šponer, 2021, The journal of physical chemistry letters.

Crystallographic observation of nonenzymatic RNA primer extension

J. Szostak, Wen Zhang, T. Walton, 2018, bioRxiv.

Structure and evolutionary analysis of a non-biological ATP-binding protein.

J. Szostak, J. Chou, S. Mansy, 2007, Journal of molecular biology.

Solvated-electron production using cyanocuprates is compatible with the UV-environment on a Hadean–Archaean Earth

J. Szostak, D. Sasselov, S. Ranjan, 2018, Chemical Communications.

Double-strand breaks at an initiation site for meiotic gene conversion

J. Szostak, N. Schultes, D. Treco, 1989, Nature.

Evolution of aptamers with a new specificity and new secondary structures from an ATP aptamer.

J. Szostak, Zhen-Hua Huang, 2003, RNA.

Functional information: Molecular messages

Jack W. Szostak, J. Szostak, 2003, Nature.

In Vitro Selection of Functional Lantipeptides

J. Szostak, F. Seebeck, F. Hofmann, 2012, Journal of the American Chemical Society.

Assembly of a Ribozyme Ligase from Short Oligomers by Nonenzymatic Ligation

J. Szostak, D. O’Flaherty, Lijun Zhou, 2020, Journal of the American Chemical Society.

In vitro genetics.

J W Szostak, J. Szostak, 1992, Trends in biochemical sciences.

DNA sequence of a mutation in the leader region of the yeast iso-1-cytochrome c mRNA

A. T. Young, J. Szostak, F. Sherman, 1981, Cell.

Nonenzymatic, template-directed ligation of oligoribonucleotides is highly regioselective for the formation of 3'-5' phosphodiester bonds.

J W Szostak, D. Bartel, J. Szostak, 1996, Journal of the American Chemical Society.

Isolation of novel ribozymes that ligate AMP-activated RNA substrates.

J. Szostak, A. Hager, 1997, Chemistry & biology.

Conformational Analysis of DNA Repair Intermediates by Time-Resolved Fluorescence Spectroscopy

J. Szostak, J. Chaput, David P Horning, 2009, The journal of physical chemistry. A.

Mutant ATP-binding RNA aptamers reveal the structural basis for ligand binding.

J. Szostak, J. Feigon, S. Butcher, 1997, Journal of molecular biology.

1H NMR studies of the high-affinity Rev binding site of the Rev responsive element of HIV-1 mRNA: base pairing in the core binding element.

D. Bartel, J. Szostak, J. Feigon, 1994, Biochemistry.

In vitro genetic analysis of the Tetrahymena self-splicing intron

R. Green, J. Szostak, A. Ellington, 1990, Nature.

Saccharomyces cerevisiae homoserine kinase is homologous to prokaryotic homoserine kinases.

J. Szostak, A. Ellington, J. Cherry, 1990, Gene.

Structural Insights into the Evolution of a Non-Biological Protein: Importance of Surface Residues in Protein Fold Optimization

Matthew D. Smith, J. Szostak, J. Chaput, 2007, PloS one.

Structural Insights into the Evolution of a Non-Biological Protein: Importance of Surface Residues in Protein Fold

J. Szostak, J. Chaput, Meitian Wang, 2007 .

Construction of a liposome dialyzer for the preparation of high-value, small-volume liposome formulations

Katarzyna P. Adamala, J. Szostak, Neha P. Kamat, 2015, Nature Protocols.

Freeze-thaw cycles enable a prebiotically plausible and continuous pathway from nucleotide activation to nonenzymatic RNA copying

J. Szostak, C. Carr, Stephanie J. Zhang, 2021, bioRxiv.

Preparation of Large Monodisperse Vesicles

Jack W. Szostak, J. Szostak, Ting F. Zhu, 2009, PloS one.

The virtual circular genome model for primordial RNA replication

J. Szostak, Dian Ding, Lijun Zhou, 2020, RNA.

An optimal degree of physical and chemical heterogeneity for the origin of life?

Jack W. Szostak, J. Szostak, 2011, Philosophical Transactions of the Royal Society B: Biological Sciences.

Core-Shell Modeling of Light Scattering by Vesicles: Effect of Size, Contents, and Lamellarity.

Anna Wang, J. Szostak, Jack W Szostak, 2019, Biophysical journal.

Selective labeling and detection of specific RNAs in an RNA mixture.

J. Szostak, Zhen-Hua Huang, 2003, Analytical biochemistry.

The Emergence of RNA from the Heterogeneous Products of Prebiotic Nucleotide Synthesis.

J. Szostak, S. Kim, D. O’Flaherty, 2021, Journal of the American Chemical Society.

Synthesis of Model Protocells Reconstructing the Emergence of Cellular Life through the

J. Szostak, S. Mansy, 2009 .

Nonenzymatic RNA-templated Synthesis of N3'→P5' Phosphoramidate DNA.

J. Szostak, D. O’Flaherty, Lijun Zhou, 2020, Bio-protocol.

Nonenzymatic Template-Directed Synthesis of Mixed-Sequence 3′-NP-DNA up to 25 Nucleotides Long Inside Model Protocells

Jack W. Szostak, J. Szostak, Derek K. O’Flaherty, 2019, Journal of the American Chemical Society.

Experimental and Computational Evidence for a Loose Transition State in Phosphoroimidazolide Hydrolysis

J. Szostak, V. Lelyveld, N. Prywes, 2016, Journal of the American Chemical Society.

Electrostatic Localization of RNA to Protocell Membranes by Cationic Hydrophobic Peptides

J. Szostak, Neha P. Kamat, Ian T Hill, 2015, Angewandte Chemie.

Formation of Protocell-like Vesicles in a Thermal Diffusion Column

Jack W. Szostak, J. Szostak, R. Bruckner, 2009, Journal of the American Chemical Society.

Template-Free Assembly of Functional RNAs by Loop-Closing Ligation

J. Szostak, J. Sutherland, Meng Su, 2022, Journal of the American Chemical Society.

Molecular crowding facilitates ribozyme-catalyzed RNA assembly

J. Szostak, Saurja DasGupta, Stephanie J. Zhang, 2023, bioRxiv.

DNA polymerase-mediated DNA synthesis on a TNA template.

John C Chaput, J. Szostak, J. Chaput, 2003, Journal of the American Chemical Society.

Kinetic explanations for the sequence biases observed in the nonenzymatic copying of RNA templates

J. Szostak, Dian Ding, Lijun Zhou, 2021, bioRxiv.

Structural interpretation of the effects of threo-nucleotides on nonenzymatic template-directed polymerization

J. Szostak, V. Lelyveld, Wen Zhang, 2020, bioRxiv.

Enhanced nonenzymatic RNA copying with in-situ activation of short oligonucleotides

J. Szostak, Stephanie J. Zhang, Dian Ding, 2023, bioRxiv.

Direct monitoring of the thermodynamics and kinetics of DNA and RNA dinucleotide dehybridization from gaps and overhangs

J. Szostak, A. Tokmakoff, J. Sachleben, 2023, bioRxiv.

Experimental Tests of the Virtual Circular Genome Model for Nonenzymatic RNA Replication

J. Szostak, S. Mittal, Dian Ding, 2023, bioRxiv.

Structure-activity relationships in nonenzymatic template-directed RNA synthesis.

J. Szostak, L. Pazienza, H. Aitken, 2021, Angewandte Chemie.

Template-Directed Catalysis of a Multistep Reaction Pathway for Nonenzymatic RNA Primer Extension

J. Szostak, T. Walton, L. Pazienza, 2018, Biochemistry.

A Kinetic Model of Nonenzymatic RNA Polymerization by Cytidine-5′-phosphoro-2-aminoimidazolide

J. Szostak, T. Walton, Jack W Szostak, 2017, Biochemistry.

A Highly Reactive Imidazolium-Bridged Dinucleotide Intermediate in Nonenzymatic RNA Primer Extension

Jack W. Szostak, J. Szostak, T. Walton, 2016, Journal of the American Chemical Society.

Bulk Self-Assembly of Giant, Unilamellar Vesicles.

J. Szostak, J. Kindt, Anna Wang, 2020, ACS nano.

Optimal codon choice can improve the efficiency and fidelity of N-methyl amino acid incorporation into peptides by in-vitro translation.

J. Szostak, Alexander O. Subtelny, Matthew C. T. Hartman, 2011, Angewandte Chemie.

Mutations in a semiconserved region of the Tetrahymena intron

J. Szostak, Umberto Pace, 1991, FEBS letters.

Mutational analysis of conserved nucleotides in a self-splicing group I intron.

R. Green, J. Doudna, J. Szostak, 1990, Journal of molecular biology.

Genetic dissection of an RNA enzyme.

J. Doudna, J. Szostak, A. S. Gerber, 1987, Cold Spring Harbor symposia on quantitative biology.

RNA structure, not sequence, determines the 5' splice-site specificity of a group I intron.

J. Doudna, J. Szostak, B. Cormack, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Identification of epitope‐like consensus motifs using mRNA display

Richard W Roberts, Martin C. Wright, Petra Burgstaller, 2002, Journal of molecular recognition : JMR.

Interpreting turbidity measurements for vesicle studies

J. Szostak, C. Miller, Anna Wang, 2018, bioRxiv.

Semipermeable lipid bilayers exhibit diastereoselectivity favoring ribose

J. Szostak, M. G. Sacerdote, J. W. Szostak, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Using Imaging Flow Cytometry to Quantify and Optimize Giant Vesicle Production by Water-in-oil Emulsion Transfer Methods.

T. Yomo, J. Szostak, M. Hanczyc, 2019, Langmuir : the ACS journal of surfaces and colloids.

The Origins of Nucleotides

J. Szostak, J. Sutherland, M. Powner, 2011 .

Comparative analysis of LIN28-RNA binding sites identified at single nucleotide resolution

J. Szostak, V. Lelyveld, L. Pantano, 2017, RNA biology.

Replicating vesicles as models of primitive cell growth and division.

Martin M Hanczyc, J. Szostak, M. Hanczyc, 2004, Current opinion in chemical biology.

Inosine, but none of the 8-oxo-purines, is a plausible component of a primordial version of RNA

Jack W. Szostak, Victor S. Lelyveld, J. Szostak, 2018, Proceedings of the National Academy of Sciences.

Isolation and characterization of fluorophore-binding RNA aptamers.

J W Szostak, J. Szostak, C. Wilson, 1998, Folding & design.

8 Using pseudorotation as a reaction coordinate in free energy simulations of nucleic acids

J. Szostak, Li Li, 2013 .

N-Carboxyanhydride-Mediated Fatty Acylation of Amino Acids and Peptides for Functionalization of Protocell Membranes

Tony Z. Jia, J. Szostak, V. Lelyveld, 2016, Journal of the American Chemical Society.

Nonenzymatic loop-closing ligation generates RNA hairpins and is a template-free way to assemble functional RNAs

J. Szostak, M. Su, J. Sutherland, 2021, bioRxiv.

Lipid Exchange Promotes Fusion of Model Protocells

T. Yomo, J. Szostak, Zhifang Fan, 2023, Small methods.

Enzymatic Primer-Extension with Glycerol-Nucleoside Triphosphates on DNA Templates

J. Szostak, Xin Cai, L. McLaughlin, 2009, PloS one.

RNA-catalyzed RNA Ligation within Prebiotically Plausible Model Protocells

J. Szostak, Saurja DasGupta, Stephanie J. Zhang, 2023, bioRxiv.

Directed evolution of ATP binding proteins from a zinc finger domain by using mRNA display.

J. Szostak, G. Cho, 2006, Chemistry & biology.

Small-Molecule Organocatalysis Facilitates In Situ Nucleotide Activation and RNA Copying

J. Szostak, A. Radaković, Tom H. Wright, 2023, Journal of the American Chemical Society.

Nonenzymatic assembly of active chimeric ribozymes from aminoacylated RNA oligonucleotides

J. Szostak, Saurja DasGupta, A. Radaković, 2021, Proceedings of the National Academy of Sciences.

A Fluorescent G-Quadruplex Sensor for Chemical RNA Copying.

J. Szostak, Tom H. Wright, D. O’Flaherty, 2018, Angewandte Chemie.

Total chemical synthesis of a ribozyme derived from a group I intron.

J. Szostak, N. Usman, S. Whoriskey, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Evolution of functional nucleic acids in the presence of nonheritable backbone heterogeneity

J. Szostak, N. Zhang, Simon G. Trevino, 2011, Proceedings of the National Academy of Sciences.

UV-light-driven prebiotic synthesis of iron-sulfur clusters.

J. Szostak, D. Sasselov, S. Mansy, 2017, Nature chemistry.

Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging

E. Blackburn, J. Szostak, C. Greider, 2006, Nature Medicine.

Transient states during the annealing of mismatched and bulged oligonucleotides

J. Szostak, Dian Ding, Marco Todisco, 2023, bioRxiv.

Protocells and RNA Self-Replication.

G. F. Joyce, J. Szostak, 2018, Cold Spring Harbor perspectives in biology.

PRELIMINARY COMMUNICATION Open Access

J. Szostak, Ting F. Zhu, 2011 .

Flip-flop-induced relaxation of bending energy: implications for membrane remodeling.

J. Szostak, S. Mansy, Raphael J. Bruckner, 2009, Biophysical journal.

Photochemically driven redox chemistry induces protocell membrane pearling and division

Katarzyna P. Adamala, J. Szostak, N. Zhang, 2012, Proceedings of the National Academy of Sciences.

Steps toward a Synthetic Protocell

Irene A. Chen, Martin M. Hanczyc, Jack W. Szostak, 2008 .

Cyclophospholipids Enable a Protocellular Life Cycle

J. Szostak, S. Mansy, R. Krishnamurthy, 2023, ACS nano.

Preparation, Purification, and Use of Fatty Acid-containing Liposomes

Katarzyna P. Adamala, J. Szostak, A. Engelhart, 2018, Journal of visualized experiments : JoVE.

Efficient and Rapid Template-Directed Nucleic Acid Copying Using 2′-Amino-2′,3′-dideoxyribonucleoside−5′-Phosphorimidazolide Monomers

J. Szostak, Jason P. Schrum, J. C. Blain, 2009, Journal of the American Chemical Society.

Competition between model protocells driven by an encapsulated catalyst.

Katarzyna P. Adamala, J. Szostak, 2013, Nature chemistry.

Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity

J. Szostak, V. Lelyveld, Ziyuan Fang, 2023, Science.

Simulations predict preferred Mg2+ coordination in a nonenzymatic primer extension reaction center

J. Szostak, S. Mittal, Collin R. Nisler, 2024, bioRxiv.

Mettl1/Wdr4-Mediated m7G tRNA Methylome Is Required for Normal mRNA Translation and Embryonic Stem Cell Self-Renewal and Differentiation.

J. Szostak, V. Lelyveld, R. Gregory, 2018, Molecular cell.

SEXUAL INDUCTION IN EUDORINA: EFFECTS OF LIGHT, NUTRIENTS, AND CONDITIONED MEDIUM 1

J. Szostak, J. Sparkuhl, M. E. Goldstein, 1973 .

Passive endocytosis in model protocells

Thomas G. Fai, J. Szostak, Yamuna Krishnan, 2023, bioRxiv.

Main Manuscript for Passive endocytosis in protocells enables nutrient transport bypassing permeability limits

Thomas G. Fai, J. Szostak, Yamuna Krishnan, 2022 .