D. Barlow

发表

Imprinting mechanisms--it only takes two.

F. Pauler, D. Barlow, 2006, Genes & development.

Active and repressive chromatin are interspersed without spreading in an imprinted gene cluster in the mammalian genome.

F. Pauler, D. Barlow, M. A. Sloane, 2007, Molecular cell.

Genomic imprinting: a mammalian epigenetic discovery model.

D. Barlow, 2011, Annual review of genetics.

An RNA-Seq Strategy to Detect the Complete Coding and Non-Coding Transcriptome Including Full-Length Imprinted Macro ncRNAs

F. Pauler, D. Barlow, H. Stunnenberg, 2011, PloS one.

Macro lncRNAs

D. Barlow, Philipp M. Guenzl, 2012, RNA biology.

H3K27me3 forms BLOCs over silent genes and intergenic regions and specifies a histone banding pattern on a mouse autosomal chromosome.

A. Aszódi, F. Pauler, D. Barlow, 2009, Genome research.

Quantitative genetics: Turning up the heat on QTL mapping

D. Barlow, F. Sleutels, R. Zwart, 2002, Nature Reviews Genetics.

The imprinted antisense RNA at the Igf2r locus overlaps but does not imprint Mas1

R. Lyle, D. Barlow, J. Schageman, 2000, Nature Genetics.

Airn Transcriptional Overlap, But Not Its lncRNA Products, Induces Imprinted Igf2r Silencing

F. Pauler, D. Barlow, Katarzyna E. Warczok, 2012, Science.

Long non-coding RNAs display higher natural expression variation than protein-coding genes in healthy humans

F. Pauler, D. Barlow, R. Kralovics, 2016, Genome Biology.

Human Copy Number Variation and Complex Genetic Disease

Rodolphe Barrangou, Asuteka Nagao, R. Barrangou, 2014 .

Investigation of Elements Sufficient To Imprint the Mouse Air Promoter

D. Barlow, F. Sleutels, 2001, Molecular and Cellular Biology.

The uniqueness of the imprinting mechanism.

R. Lyle, D. Barlow, F. Sleutels, 2000, Current opinion in genetics & development.

A human haploid gene trap collection to study lncRNAs with unusual RNA biology

F. Pauler, D. Barlow, Irena Vlatkovic, 2015, RNA biology.

Genomic imprinting in mammals.

Denise P Barlow, D. Barlow, M. Bartolomei, 2014, Cold Spring Harbor perspectives in biology.

Close genetic and physical linkage between the murine haemopoietic growth factor genes GM‐CSF and Multi‐CSF (IL3).

M. Bucan, H. Lehrach, D. Barlow, 1987, The EMBO journal.

Extensive homology between the carboxyl-terminal peptides of mouse alpha 1(IV) and alpha 2(IV) collagen.

D. Barlow, T. Pihlajaniemi, J. Saus, 1987, The Journal of biological chemistry.

Imprinted expression in cystic embryoid bodies shows an embryonic and not an extra-embryonic pattern

D. Barlow, C. Bock, J. Penninger, 2015, Developmental biology.

Impaired Activity of the Extraneuronal Monoamine Transporter System Known as Uptake-2 inOrct3/Slc22a3-Deficient Mice

D. Barlow, M. Buitelaar, R. Zwart, 2001, Molecular and Cellular Biology.

The Lxl gene maps to mouse Chromosome 17 and codes for a protein that is homologous to glucose and polyspecific transmembrane transporters

D. Barlow, N. Schweifer, Denise P. Barlow, 1996, Mammalian Genome.

Mouse chromosome 17

M. Lyon, H. Himmelbauer, L. Silver, 2004, Mammalian Genome.

Imprinted genes are epigenetically silenced on one of the two parental chromosomes in diploid embryonic cells. More than 30 protein-coding genes, plus a growing number of non-coding RNAs, have now been shown to be imprinted in both mice

R. Jaenisch, D. Barlow, J. Dausman, 2001 .

Genetic analysis of the organic cation transporter genes Orct2/Slc22a2 and Orct3/Slc22a3 reduces the critical region for the t haplotype mutant tw73 to 200 kb

M. Lyon, D. Barlow, R. Zwart, 2001, Mammalian Genome.

Deficient Mice Orct 3 / Slc 22 a 3-Uptake-2 in Monoamine Transporter System Known as Impaired Activity of the Extraneuronal

Corrie, D. Barlow, M. Buitelaar, 2001 .

CONTROL PROCESSES IN INTERFERON PRODUCTION11This work was supported by grants from the Medical Research Council, the Science Research Council and the Wellcome Trust.

D. Barlow, D. Burke, J. Morser, 1982 .

Imprinting of the mouse Igf2r gene depends on an intronic CpG island

D. Barlow, A. Wutz, 1998, Molecular and Cellular Endocrinology.

Competition—a common motif for the imprinting mechanism?

D. Barlow, 1997, The EMBO journal.

Imprinting: a gamete's point of view.

D. Barlow, 1994, Trends in genetics : TIG.

Mapping the mouse Allelome reveals tissue-specific regulation of allelic expression

F. Pauler, D. Barlow, C. Bock, 2017, eLife.

The origins of genomic imprinting in mammals.

D. Barlow, F. Sleutels, 2002, Advances in genetics.

Characterization of 64-, 123- and 182-base-pair exons in the mouse α2(IV) collagen gene

D. Barlow, L. Chow, M. Bernard, 1985, Nature.

Linkage of genes for laminin B1 and B2 subunits on chromosome 1 in mouse

R. Elliott, D. Barlow, B. Hogan, 1985, In Vitro Cellular & Developmental Biology.

Cloning Development Mutants from the Mouse t Complex

D. Barlow, 1992 .

[26] Molecular cloning of laminin

D. Barlow, B. Hogan, J. McVey, 1987 .

Interferon synthesis in the early post-implantation mouse embryo.

D. Barlow, D. Burke, B. Randle, 1984, Differentiation; research in biological diversity.

Chromosomal assignments of the genes coding for human types II, III, and IV collagen: a dispersed gene family.

D. Barlow, B. Hogan, R. Dalgleish, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Imprintedexpressionof the Igf 2 r genedepends onan intronicCpG island

E. Wagner, D. Barlow, K. Schellander, 1997 .

Reichert's membrane as a model for studying the biosynthesis and assembly of basement membrane components.

D. Barlow, B. Hogan, M. Kurkinen, 1984, Ciba Foundation symposium.

Regulation of embryonic growth and lysosomal targeting by the imprintedIgf2/Mpr gene

E. Wagner, D. Barlow, Zhao-Qi Wang, 1994, Nature.

Denise Barlow: A career in epigenetics

D. Barlow, 2015, RNA biology.

Titin antibodies in myasthenia gravis

D. Barlow, N. Gilhus, M. Gautel, 1993, Neurology.

Construction and use of human chromosome jumping libraries from NotI-digested DNA

A. Poustka, H. Lehrach, D. Barlow, 1987, Nature.

Gene regulation by the act of long non-coding RNA transcription

Denise P Barlow, F. Pauler, D. Barlow, 2013, BMC Biology.

Mouse embryonic germ (EG) cell lines: transmission through the germline and differences in the methylation imprint of insulin-like growth factor 2 receptor (Igf2r) gene compared with embryonic stem (ES) cell lines.

D. Barlow, B. Hogan, P. Labosky, 1994, Development.

Mouse chromosome 17

M. Lyon, L. Silver, D. Barlow, 2004, Mammalian Genome.

Mouse Chromosome 17

M. Lyon, L. Silver, D. Barlow, 2004, Mammalian Genome.

The interferon system in the developing mouse embryo and in differentiating teratocarcinoma cells.

D. Barlow, 1981 .

In vitro synthesis of laminin and entactin polypeptides.

D. Barlow, B. Hogan, J. Jenkins, 1983, The Journal of biological chemistry.

In vitro synthesis of type IV procollagen.

D. Barlow, B. Hogan, M. Kurkinen, 1981, The Journal of biological chemistry.

Silencing by imprinted noncoding RNAs: is transcription the answer?

F. Pauler, D. Barlow, Martha V. Koerner, 2007, Trends in genetics : TIG.

The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus

D. Barlow, B. Herrmann, N. Schweifer, 1991, Nature.

The function of non-coding RNAs in genomic imprinting

Ru Huang, F. Pauler, D. Barlow, 2009, Development.

5 The origins of genomic imprinting in mammals

D. Barlow, F. Sleutels, 2002 .

Non-imprinted Igf2r expression decreases growth and rescues the Tme mutation in mice.

R. Jaenisch, E. Wagner, D. Barlow, 2001, Development.

Imprinted expression of the Igf2r gene depends on an intronic CpG island

E. Wagner, D. Barlow, K. Schellander, 1997, Nature.

Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal

D. Barlow, A. Razin, H. Cedar, 1993, Cell.

Considerations when investigating lncRNA function in vivo

Wilfried Haerty, Thomas R Gingeras, Denise P Barlow, 2014, eLife.

Considerations when investigating lncRNA function

Andrew R. Bassett, C. Ponting, A. Bird, 2014 .

Explorer Considerations when investigating lncRNA function in vivo

Andrew R. Bassett, T. Gingeras, E. Miska, 2014 .

Allelome.PRO, a pipeline to define allele-specific genomic features from high-throughput sequencing data

F. Pauler, D. Barlow, Christoph P. Dotter, 2015, Nucleic acids research.

Considerations when investigating lncRNA function in vivo

Andrew R. Bassett, C. Ponting, A. Bird, 2014, eLife.

The Air noncoding RNA: an imprinted cis-silencing transcript.

F. Pauler, D. Barlow, S. Stricker, 2004, Cold Spring Harbor symposia on quantitative biology.

The mouse plasminogen locus maps to the recombination breakpoints of the tLub2and TtOrlpartial t haplotypes but is not at the tw73locus

D. Barlow, N. Schweifer, 2004, Mammalian Genome.

Imprinted Igf2r silencing depends on continuous Airn lncRNA expression and is not restricted to a developmental window

A. Stukalov, F. Pauler, D. Barlow, 2013, Development.

Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal.

D. Barlow, A. Razin, H. Cedar, 1993, Cell.

Imprinted silencing of Slc22a2 and Slc22a3 does not need transcriptional overlap between Igf2r and Air

T. Ludwig, D. Barlow, F. Sleutels, 2003, The EMBO journal.

Bidirectional action of the Igf2r imprint control element on upstream and downstream imprinted genes.

D. Barlow, F. Sleutels, A. Wutz, 2001, Genes & development.

An in vitro ES cell imprinting model shows that imprinted expression of the Igf2r gene arises from an allele-specific expression bias

F. Pauler, D. Barlow, K. Regha, 2009, Development.

Paternal repression of the imprinted mouse Igf2r locus occurs during implantation and is stable in all tissues of the post-implantation mouse embryo

D. Barlow, W. Lerchner, 1997, Mechanisms of Development.

Regulation of imprinted expression by macro non-coding RNAs

D. Barlow, P. Latos, 2009, RNA biology.

Genomic imprinting-an epigenetic gene-regulatory model.

D. Barlow, Martha V. Koerner, 2010, Current opinion in genetics & development.

A large inverted duplication allows homologous recombination between chromosomes heterozygous for the proximal t complex inversion

Hans Lehrach, H. Lehrach, D. Barlow, 1987, Cell.

Characteristics of imprinted genes

D. Barlow, B. Neumann, P. Kubicka, 1995, Nature Genetics.

Deacetylase Enzymes Erasers of Histone Acetylation : The Histone

J. Workman, D. Barlow, Yi Zhang, 2013 .

Developmental control of imprinted expression by macro non-coding RNAs.

D. Barlow, Federica Santoro, 2011, Seminars in cell & developmental biology.

Extra-embryonic-specific imprinted expression is restricted to defined lineages in the post-implantation embryo.

D. Barlow, R. Huang, Katarzyna E. Warczok, 2011, Developmental biology.

Genomic imprinting mechanisms in embryonic and extraembryonic mouse tissues

D. Barlow, Q. Hudson, S. Huetter, 2010, Heredity.

Long-range DNase I hypersensitivity mapping reveals the imprinted Igf2r and Air promoters share cis-regulatory elements.

F. Pauler, D. Barlow, Katarzyna E. Warczok, 2005, Genome research.

Gametic imprinting at the mouse and human IGF2R/MPR300 locus

D. Barlow, O. Smrzka, 1997 .

Genetics by gel electrophoresis: the impact of pulsed field gel electrophoresis on mammalian genetics

H. Lehrach, D. Barlow, 1987 .

Sequencing of laminin B chain cDNAs reveals C‐terminal regions of coiled‐coil alpha‐helix.

D. Barlow, B. Hogan, N. Green, 1984, The EMBO journal.

Identification of the human homolog of the imprinted mouse Air non-coding RNA.

E. Wagner, M. Oshimura, F. Pauler, 2008, Genomics.

Conservation of a maternal-specific methylation signal at the human IGF2R locus.

D. Barlow, R. Kurzbauer, T. Henn, 1995, Human molecular genetics.

A regular pattern of two types of 100-residue motif in the sequence of titin

T. Gibson, D. Barlow, U. Francke, 1990, Nature.

An ICE pattern crystallizes

D. Barlow, L. Spahn, 2003, Nature Genetics.

Characterization of the C3 YAC contig from proximal mouse chromosome 17 and analysis of allelic expression of genes flanking the imprinted Igf2r gene.

S. Meier-Ewert, H. Lehrach, R. Cox, 1997, Genomics.

Random and imprinted monoallelic expression

D. Barlow, D. Watanabe, D P Barlow, 1996, Genes to cells : devoted to molecular & cellular mechanisms.

Gametic Imprinting in Mammals

D. Barlow, D P Barlow, 1995, Science.

Mechanisms of long range silencing by imprinted macro non-coding RNAs

Denise P Barlow, F. Pauler, D. Barlow, 2012, Current opinion in genetics & development.

Impressions of imprints.

D. Barlow, R. Ohlsson, Azim Surani, 1994, Trends in genetics : TIG.

Cloning of the mouse and human solute carrier 22a3 (Slc22a3/SLC22A3) identifies a conserved cluster of three organic cation transporters on mouse chromosome 17 and human 6q26-q27.

D. Barlow, N. Schweifer, R. Zwart, 1999, Genomics.

Imprinted silencing is extended over broad chromosomal domains in mouse extra-embryonic lineages

D. Barlow, Q. Hudson, T. Kuliński, 2013, Current opinion in cell biology.

The imprinted Air ncRNA is an atypical RNAPII transcript that evades splicing and escapes nuclear export

D. Barlow, S. Stricker, C. Seidl, 2006, The EMBO journal.

Silencing and transcriptional properties of the imprinted Airn ncRNA are independent of the endogenous promoter

F. Pauler, D. Barlow, M. A. Sloane, 2008, The EMBO journal.

A Downstream CpG Island Controls Transcript Initiation and Elongation and the Methylation State of the Imprinted Airn Macro ncRNA Promoter

F. Pauler, D. Barlow, Katarzyna E. Warczok, 2012, PLoS genetics.

Multiple roles for DNA methylation in gametic imprinting.

D. Barlow, B. Neumann, 1996, Current opinion in genetics & development.

Making sense of imprinting the mouse and human IGF2R loci.

D. Barlow, A. Wutz, O. Smrzka, 1998, Novartis Foundation symposium.

Identification of a male meiosis-specific gene, Tcte2, which is differentially spliced in species that form sterile hybrids with laboratory mice and deleted in t chromosomes showing meiotic drive.

D. Barlow, G. Braidotti, 1997, Developmental biology.

Isolation of cDNA clones for basal lamina components: type IV procollagen.

D. Helfman, D. Barlow, B. Hogan, 1983, Nucleic acids research.

The extraneuronal monoamine transporter Slc22a3/Orct3 co-localizes with the Maoa metabolizing enzyme in mouse placenta

D. Barlow, R. Zwart, S. Verhaagh, 2001, Mechanisms of Development.

Embryonic germ cell lines and their derivation from mouse primordial germ cells.

D. Barlow, B. Hogan, P. Labosky, 2007, Ciba Foundation symposium.

Three linked myosin heavy chain genes clustered within 370 kb of each other show independent transcriptional and post-transcriptional regulation during differentiation of a mouse muscle cell line.

D. Barlow, M. Buckingham, A. Weydert, 1991, Developmental biology.

Kettin, a large modular protein in the Z‐disc of insect muscles.

D. Barlow, M. Gautel, K. Leonard, 1993, The EMBO journal.

Pattern of serum protein gene expression in mouse visceral yolk sac and foetal liver.

D. Barlow, B. Hogan, R. Meehan, 1984, The EMBO journal.

Tissue‐specific Gene Expression in Mouse F9 Embryonal Carcinoma Cells: Type IV Collagen

D. Barlow, B. Hogan, M. Kurkinen, 1985, Annals of the New York Academy of Sciences.

The non-coding Air RNA is required for silencing autosomal imprinted genes

D. Barlow, F. Sleutels, R. Zwart, 2002, Nature.