B. Lipworth

B. Lipworth, A. Nair, J. Ward, 2011, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Pragmatic clinical perspective on biologics for severe refractory type 2 asthma.

B. Lipworth, R. Chan, C. Kuo, 2020, The journal of allergy and clinical immunology. In practice.

Combined mediator antagonism for allergic rhinitis

B. Lipworth, C. Jackson, 2004, Allergy.

Association between β2-adrenoceptor polymorphism and susceptibility to bronchodilator desensitisation in moderately severe stable asthmatics

Brian Lipworth, I. Hall, B. Lipworth, 1997, The Lancet.

Long-Acting β2-Agonists in Asthma

B. Lipworth, G. Currie, Daniel K. C. Lee, 2006 .

Differential anti‐inflammatory effects of large and small particle size inhaled corticosteroids in asthma

B. Lipworth, A. Nair, D. Menzies, 2007, Allergy.

British Journal of Clinical Pharmacology

B. Lipworth, P. Waller, G. Tucker, 2013 .

5-Lipoxygenase polymorphism and in-vivo response to leukotriene receptor antagonists

I. Hall, A. Wheatley, B. Lipworth, 2002, European Journal of Clinical Pharmacology.

The biochemical effects of high-dose inhaled salbutamol in patients with asthma

B. Lipworth, D. McDevitt, R. Clark, 2004, European Journal of Clinical Pharmacology.

Adverse effects of long-acting beta-agonists on airway hyperresponsiveness.

B. Lipworth, A. Manoharan, P. Short, 2013, American journal of respiratory cell and molecular biology.

Dose-response evaluation of the therapeutic index for inhaled budesonide in patients with mild-to-moderate asthma.

B. Lipworth, A. Wilson, A. Wilson, 2000, The American journal of medicine.

Adrenergic beta(2)-receptor genotype predisposes to exacerbations in steroid-treated asthmatic patients taking frequent albuterol or salmeterol.

B. Lipworth, C. Palmer, S. Mukhopadhyay, 2009, The Journal of allergy and clinical immunology.

Randomized placebo-controlled trial to evaluate chronic dosing effects of propranolol in asthma.

B. Lipworth, P. Williamson, P. Short, 2013, American journal of respiratory and critical care medicine.

Prescribing of β-adrenoceptor antagonists in asthma: an observational study

P. Donnan, C. Jackson, B. Lipworth, 2011, Thorax.

Response to salbutamol in patients with mild asthma treated with nadolol

B. Lipworth, N. Hanania, P. Williamson, 2010, European Respiratory Journal.

β blockers for asthma: a double-edged sword

B. Lipworth, P. Williamson, 2009, The Lancet.

Think the impossible: beta-blockers for treating asthma.

B. Lipworth, P. Williamson, 2009, Clinical science.

The effects of chronic dosing on the β1 and β2-adrenoceptor antagonism of betaxolol and atenolol

B. Lipworth, D. McDevitt, N. Irvine, 2004, European Journal of Clinical Pharmacology.

The effects of time and dose on the relative beta 1- and beta 2-adrenoceptor antagonism of betaxolol and atenolol.

B. Lipworth, D. McDevitt, N. Irvine, 1991, British journal of clinical pharmacology.

A dose-ranging study to evaluate the beta-adrenoceptor selectivity of single doses of betaxolol.

B. Lipworth, D. McDevitt, N. Irvine, 1990, British journal of clinical pharmacology.

Longitudinal Data on Positive Tuberculin Skin Tests From Three US States

B. Lipworth, H. Colt, D. J. Castro, 2000 .

Beta-adrenoceptor responses to high doses of inhaled salbutamol in patients with bronchial asthma.

B. Lipworth, D. Dhillon, D. McDevitt, 1988, British journal of clinical pharmacology.

Reaudit of Acute Asthma Admissions Using a Severity Marker Stamp and Determinants of an Outcome Measure

B. Lipworth, D. Dhillon, R. Clark, 1997, Scottish medical journal.

Does Bronchial Hyperresponsiveness in Asthma Matter?

C. Jackson, B. Lipworth, G. Currie, 2004, The Journal of asthma : official journal of the Association for the Care of Asthma.

Relationship between airway hyperresponsiveness to mannitol and adenosine monophosphate

S. Anderson, B. Lipworth, J. Brannan, 2003, Allergy.

Optimizing bronchodilator therapy for copd.

B. Lipworth, 2001, Chest.

Revisiting interactions between hypoxaemia and beta2 agonists in asthma.

B. Lipworth, Lipworth Bj, 2001, Thorax.

Dose-Response of Inhaled Drugs in Asthma

B. Lipworth, D. Clark, 1997, Clinical pharmacokinetics.

Comparison of the relative airways and systemic potencies of inhaled fenoterol and salbutamol in asthmatic patients.

B. Lipworth, D. Dhillon, D. McDevitt, 1995, Thorax.

Single dosing comparison of the relative cardiac beta 1/beta 2 activity of inhaled fenoterol and salbutamol in normal subjects.

B. Lipworth, D. McDevitt, D. Newnham, 1993, Thorax.

Inhaled beta 2-adrenoceptor agonists in asthma: help or hindrance?

B. Lipworth, D. McDevitt, 1992, British journal of clinical pharmacology.

The β‐agonist controversy: fact or fiction?

B. Lipworth, 1992 .

Risks Versus Benefits of Inhaled β2-Agonists in the Management of Asthma

B. Lipworth, 1992 .

Lung delivery of salbutamol by dry powder inhaler (Turbuhaler) and small volume antistatic metal spacer (Airomir CFC-free MDI plus NebuChamber).

B. Lipworth, D. Clark, D. Clark, 1997, The European respiratory journal.

Cardiopulmonary effects of endothelin-1 in man.

B. Lipworth, A. Struthers, D. Kiely, 1997, Cardiovascular research.

Comparison of the extrapulmonary beta2-adrenoceptor responses and pharmacokinetics of salbutamol given by standard metered dose-inhaler and modified actuator device.

B. Lipworth, D. McDevitt, D. Newnham, 1993, British journal of clinical pharmacology.

Respiratory effect of beta-blocker eye drops in asthma: population-based study and meta-analysis of clinical trials.

P. Donnan, C. Jackson, B. Lipworth, 2016, British journal of clinical pharmacology.

Tolerability of Bisoprolol on Domiciliary Spirometry in COPD

B. Lipworth, S. Jabbal, 2018, Lung.

Second-Line Controller Therapy for Persistent Asthma Uncontrolled on Inhaled Corticosteroids

C. Jackson, B. Lipworth, 2012, Drugs.

A proof of concept study to evaluate putative benefits of montelukast in moderate persistent asthmatics.

B. Lipworth, S. Fowler, O. J. Dempsey, 2003, British journal of clinical pharmacology.

Add-on therapy with montelukast or formoterol in patients with the glycine-16 beta2-receptor genotype.

C. Jackson, B. Lipworth, E. Sims, 2003, British journal of clinical pharmacology.

Concomitant occasional use of salbutamol influences bronchoprotective responsiveness afforded by formoterol in patients with the glycine-16 genotype

B. Lipworth, E. Sims, 2003, European Journal of Clinical Pharmacology.

Fluticasone propionate/salmeterol combination.

B. Lipworth, 2001, The Journal of allergy and clinical immunology.

Effects of adding a leukotriene antagonist or a long-acting beta(2)-agonist in asthmatic patients with the glycine-16 beta(2)-adrenoceptor genotype.

B. Lipworth, A. Wilson, O. J. Dempsey, 2000, The American journal of medicine.

Problems with asthma following treatment of thyrotoxicosis.

B. Lipworth, R. Newton, D. Dhillon, 1988, British journal of diseases of the chest.

Effects of fexofenadine and desloratadine on subjective and objective measures of nasal congestion in seasonal allergic rhinitis

B. Lipworth, A. Wilson, E. Sims, 2002, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Reproducibility of response to nasal lysine-aspirin challenge in patients with aspirin-induced asthma.

B. Lipworth, Daniel K. C. Lee, K. Haggart, 2004, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Effects of lisinopril on congestive heart failure in normotensive patients with diastolic dysfunction but intact systolic function

B. Lipworth, C. Lang, A. Struthers, 2004, European Journal of Clinical Pharmacology.

Effects of the inverse alpha‐agonist doxazosin in allergic rhinitis

B. Lipworth, A. Manoharan, A. Morrison, 2016, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Impact of Left Ventricular Hypertrophy on Survival in Chronic Obstructive Pulmonary Disease

B. Lipworth, A. Struthers, D. Elder, 2015, Lung.

Regular use of salbutamol in asthma

B. Lipworth, S. Fowler, 2000, The Lancet.

Considerations of a real life pragmatic clinical trial in adolescent asthma

B. Lipworth, S. Mukhopadhyay, T. Ruffles, 2021, European Respiratory Journal.

Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases

A. Sheikh, T. To, R. Picard, 2019, Clinical and Translational Allergy.

Does unified allergic airway disease impact on lung function and type 2 biomarkers?

B. Lipworth, R. Chan, C. Kuo, 2019, Allergy, Asthma & Clinical Immunology.

MASK 2017: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma multimorbidity using real-world-evidence

Rosalind W. Picard, D. Ryan, A. Sheikh, 2018, Clinical and Translational Allergy.

Effects of levocetirizine as add‐on therapy to fluticasone in seasonal allergic rhinitis

B. Lipworth, T. Fardon, M. Barnes, 2006, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Loss of normal cyclical beta 2 adrenoceptor regulation and increased premenstrual responsiveness to adenosine monophosphate in stable female asthmatic patients.

B. Lipworth, K. Tan, L. McFarlane, 1997, Thorax.

Impact of Long-Acting Bronchodilators and Exposure to Inhaled Corticosteroids on Mortality in COPD: A Real-Life Retrospective Cohort Study

B. Lipworth, A. Manoharan, W. Anderson, 2014, Lung.

A proof of concept study to evaluate stepping down the dose of fluticasone in combination with salmeterol and tiotropium in severe persistent asthma.

B. Lipworth, Daniel K. C. Lee, T. Fardon, 2007, Respiratory medicine.

Prior treatment with diuretic augments the hypokalemic and electrocardiographic effects of inhaled albuterol.

B. Lipworth, A. Struthers, D. McDevitt, 1989, The American journal of medicine.

Cross tolerance to salbutamol occurs independently of β2 adrenoceptor genotype-16 in asthmatic patients receiving regular formoterol or salmeterol

C. Jackson, B. Lipworth, D. K. Lee, 2004, Thorax.

The effects of frusemide and triamterene on the hypokalaemic and electrocardiographic responses to inhaled terbutaline.

B. Lipworth, D. McDevitt, D. Newnham, 1991, British journal of clinical pharmacology.

Left ventricular hypertrophy in COPD without hypoxemia: the elephant in the room?

B. Lipworth, A. Struthers, J. George, 2013, Chest.

Effects of frusemide and hypoxia on the pulmonary vascular bed in man.

B. Lipworth, D. Kiely, R. Cargill, 2003, British journal of clinical pharmacology.

Simvastatin does not exhibit therapeutic anti-inflammatory effects in asthma.

B. Lipworth, A. Nair, D. Fleming, 2007, The Journal of allergy and clinical immunology.

Dose response of inhaled corticosteroids on bronchial hyperresponsiveness: a meta-analysis.

B. Lipworth, S. Fowler, G. Currie, 2003, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Inflammation, glucocorticoids and risk of cardiovascular disease

B. Lipworth, G. Burmester, F. Buttgereit, 2009, Nature Clinical Practice Rheumatology.

Tachyphylaxis to systemic but not to airway responses during prolonged therapy with high dose inhaled salbutamol in asthmatics.

B. Lipworth, A. Struthers, D. McDevitt, 1989, The American review of respiratory disease.

Salmeterol and inhaled corticosteroids in patients with persistent asthma.

B. Lipworth, S. Fowler, 2001, JAMA.

Glycopyrrolate/formoterol fumarate metered dose inhaler for maintenance-naïve patients with chronic obstructive pulmonary disease: a post-hoc analysis of the randomized PINNACLE trials

B. Lipworth, Jinping Zheng, P. Assam, 2020, Respiratory Research.

Effects of Adding Tiotropium or Aclidinium as Triple Therapy Using Impulse Oscillometry in COPD

B. Lipworth, A. Manoharan, A. Morrison, 2016, Lung.

Emerging role of long acting muscarinic antagonists for asthma

B. Lipworth, 2014, British journal of clinical pharmacology.

Is a Positive Nasal Lysine–Aspirin Challenge Test Associated with a More Severe Phenotype of Chronic Rhinosinusitis and Asthma?

B. Lipworth, P. Williamson, S. Vaidyanathan, 2012, American journal of rhinology & allergy.

Airway dysfunction in nasal polyposis: a spectrum of asthmatic disease?

B. Lipworth, P. Williamson, K. Clearie, 2011, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Pulmonary arterial stiffening in COPD and its implications for right ventricular remodelling

B. Lipworth, A. Struthers, J. Weir-McCall, 2018, European Radiology.

The Art and Science of Diagnosing Interstitial Lung Diseases

L. Trupin, B. Lipworth, J. Balmes, 2009 .

Elevated levels of natriuretic peptides in patients with pulmonary thromboembolism.

B. Lipworth, O. Pirzada, A. Struthers, 2005, Respiratory medicine.

Will New Diagnostic Tests and Antiviral Drugs Make a Difference

B. Lipworth, 2015 .

Effects of contrast administration on cardiac MRI volumetric, flow and pulse wave velocity quantification using manual and software-based analysis

B. Lipworth, A. Struthers, J. Weir-McCall, 2017, The British journal of radiology.

Beta-adrenoceptor responses to inhaled salbutamol in normal subjects

B. Lipworth, D. McDevitt, 2004, European Journal of Clinical Pharmacology.

Beta-adrenoceptor subtypes mediating the airways response to BRL 35135 in man.

B. Lipworth, D. Newnham, A. Mackie, 1993, British journal of clinical pharmacology.

Assessment of airways, tremor and chronotropic responses to inhaled salbutamol in the quantification of beta 2-adrenoceptor blockade.

B. Lipworth, D. McDevitt, R. A. Brown, 1989, British journal of clinical pharmacology.

Effects of genetic polymorphism on ex vivo and in vivo function of beta2-adrenoceptors in asthmatic patients.

I. Hall, B. Lipworth, W. Coutie, 1999, Chest.

Airway and systemic effects of soluble and suspension formulations of nebulized budesonide in asthmatic children.

B. Lipworth, P. Williamson, S. Mukhopadhyay, 2009, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

NSAID‐exacerbated respiratory disease: a meta‐analysis evaluating prevalence, mean provocative dose of aspirin and increased asthma morbidity

P. Donnan, C. Jackson, B. Lipworth, 2015, Allergy.

Potentially hazardous co-prescribing of beta-adrenoceptor antagonists and agonists in the community.

B. Lipworth, J. Evans, T. MacDonald, 1996, The British journal of general practice : the journal of the Royal College of General Practitioners.

Effects of regular salmeterol on lung function and exercise capacity in patients with chronic obstructive airways disease.

B. Lipworth, D. Dhillon, J. Winter, 1996, Thorax.

Comparison of the effects of prolonged treatment with low and high doses of inhaled terbutaline on beta-adrenoceptor responsiveness in patients with chronic obstructive pulmonary disease.

B. Lipworth, D. Dhillon, D. McDevitt, 1990, The American review of respiratory disease.

The impact of tiotropium on mortality and exacerbations when added to inhaled corticosteroids and long-acting β-agonist therapy in COPD.

B. Lipworth, S. Lipworth, P. Williamson, 2012, Chest.

A pragmatic approach to simplify inhaler therapy for COPD.

B. Lipworth, S. Jabbal, 2017, The Lancet. Respiratory medicine.

Cardiac effects of the beta 3-adrenoceptor agonist BRL35135 in man.

B. Lipworth, D. McDevitt, N. Wheeldon, 1994, British journal of clinical pharmacology.

An audit of hospital discharge letters in patients admitted with acute asthma. Tayside Asthma Audit Group.

B. Lipworth, J. Allan, R. Clark, 1993, Scottish medical journal.

Clinical pharmacology of b 3-adrenoceptors

B. Lipworth, 1996 .

The role of long-acting β-agonists in patients uncontrolled on inhaled steroids alone – a pharmacological approach

B. Lipworth, 2001 .

Anti-inflammatory reliever therapy for asthma.

B. Lipworth, R. Chan, Chris RuiWen Kuo, 2020, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Benefits of glycopyrrolate/formoterol fumarate metered dose inhaler (GFF MDI) in improving lung function and reducing exacerbations in patients with moderate-to-very severe COPD: a pooled analysis of the PINNACLE studies

F. Martinez, K. Rabe, B. Lipworth, 2020, Respiratory Research.

The potential role of direct and indirect bronchial challenge testing to identify overtreatment of community managed asthma

B. Lipworth, A. Manoharan, C. Jackson, 2014, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Assessment of Spirometry and Impulse Oscillometry in Relation to Asthma Control

B. Lipworth, A. Manoharan, W. Anderson, 2015, Lung.

A randomized primary care trial of steroid titration against mannitol in persistent asthma: STAMINA trial.

C. Jackson, B. Lipworth, P. Williamson, 2012, Chest.

Relationship between fractional exhaled nitric oxide and nasal nitric oxide in airways disease.

B. Lipworth, P. Williamson, S. Vaidyanathan, 2010, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Bronchodilator subsensitivity after chronic dosing with eformoterol in patients with asthma.

B. Lipworth, D. McDevitt, D. Newnham, 1994, The American journal of medicine.

A comparison of topical budesonide and oral montelukast in seasonal allergic rhinitis and asthma

B. Lipworth, A. Wilson, O. J. Dempsey, 2001, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

FULFIL an Unmet Need in Chronic Obstructive Pulmonary Disease.

B. Lipworth, S. Jabbal, 2017, American journal of respiratory and critical care medicine.

Small airway dysfunction is associated with poorer asthma control

B. Lipworth, A. Manoharan, W. Anderson, 2014, European Respiratory Journal.

Targeting the small airways asthma phenotype: if we can reach it, should we treat it?

B. Lipworth, 2013, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Systemic bioavailability of hydrofluoroalkane (HFA) formulations of fluticasone/salmeterol in healthy volunteers via pMDI alone and spacer.

B. Lipworth, H. Nell, P. Williamson, 2010, British journal of clinical pharmacology.

An own GOAL or a real breakthrough?

B. Lipworth, T. Fardon, 2005, American journal of respiratory and critical care medicine.

Addition of fexofenadine to inhaled corticosteroid therapy to reduce inflammatory biomarkers in atopic asthma.

B. Lipworth, Daniel K. C. Lee, T. Fardon, 2005, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Forced Vital Capacity and Low Frequency Reactance Area Measurements Are Associated with Asthma Control and Exacerbations

B. Lipworth, R. Chan, 2022, Lung.

Randomized controlled trial of triple versus dual inhaler therapy on small airways in smoking asthmatics

B. Lipworth, S. Jabbal, C. Kuo, 2020, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

2020 Updated Asthma Guidelines: Clinical utility of fractional exhaled nitric oxide (Feno) in asthma management.

B. Lipworth, R. Chan, C. Kuo, 2020, The Journal of allergy and clinical immunology.

Pragmatic evaluation of inhaled corticosteroid particle size formulations on asthma control

B. Lipworth, S. Jabbal, C. Kuo, 2019, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Tiotropium in asthma.

B. Lipworth, 2012, The Lancet. Respiratory medicine.

Lack of clinically relevant differences between combination therapy and monotherapy in COPD

B. Lipworth, 2014, European Respiratory Journal.

Elevated levels of brain natriuretic peptide in acute hypoxaemic chronic obstructive pulmonary disease.

B. Lipworth, C. Lang, A. Struthers, 1992, Clinical science.

Evaluation of the metabolic responses to inhaled salbutamol in the measurement of beta2-adrenoceptor blockade

B. Lipworth, D. McDevitt, W. Coutie, 2004, European Journal of Clinical Pharmacology.

Atrial natriuretic peptide and brain natriuretic peptide in cor pulmonale. Hemodynamic and endocrine effects.

B. Lipworth, R. Cargill, 1996, Chest.

Increased plasma levels of brain natriuretic peptide in patients with isolated diastolic dysfunction.

B. Lipworth, C. Lang, T. MacDonald, 1994, American heart journal.

Pulmonary vasorelaxant activity of atrial natriuretic peptide and brain natriuretic peptide in humans.

B. Lipworth, R. Cargill, R. I. Cargill, 1995, Thorax.

Does the asthma visual analog scale relate to the Asthma Control Questionnaire?

B. Lipworth, S. Jabbal, 2018, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Symptoms, spirometry, exhaled nitric oxide, and asthma exacerbations in clinical practice.

C. Jackson, B. Lipworth, R. Houston, 2008, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

An in vivo and in vitro comparison of inhaled steroid delivery via a novel vortex actuator and a conventional valved holding chamber.

B. Lipworth, A. Nair, D. Menzies, 2007, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Non-Invasive Measurement of Airway Inflammation in Asthma

B. Lipworth, A. Nair, D. Menzies, 2006, The Journal of asthma : official journal of the Association for the Care of Asthma.

A comparison of 2 extrafine hydrofluoroalkane-134a-beclomethasone formulations on methacholine hyperresponsiveness.

B. Lipworth, T. Fardon, M. Barnes, 2006, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Pharmacological interventions and outcome measurements in the unified airway

B. Lipworth, 2005 .

Adrenal suppression with dry powder formulations of fluticasone propionate and mometasone furoate.

B. Lipworth, Daniel K. C. Lee, L. McFarlane, 2004, American journal of respiratory and critical care medicine.

Targets for inhaled treatment.

B. Lipworth, 2000, Respiratory medicine.

Effects of low and high doses of inhaled flunisolide and triamcinolone acetonide on basal and dynamic measures of adrenocortical activity in healthy volunteers.

B. Lipworth, A. Wilson, L. McFarlane, 1998, The Journal of clinical endocrinology and metabolism.

Treatment of acute asthma

B. Lipworth, 1997, The Lancet.

Effects of airway calibre on lung delivery of nebulised salbutamol.

B. Lipworth, D. Clark, 1997, Thorax.

Adverse effects of hypoxaemia on diastolic filling in humans.

B. Lipworth, D. Kiely, R. Cargill, 1995, Clinical science.

Inhaled corticosteroid therapy reduces the early morning peak in cortisol and aldosterone

B. Lipworth, A. Struthers, E. Sims, 1998 .

Inhaled corticosteroid therapy reduces the early morning peak in cortisol and aldosterone.

B. Lipworth, A. Struthers, A. Wilson, 1998, Clinical science.

Beta-adrenoceptor subtypes mediating the metabolic effects of BRL 35135 in man.

B. Lipworth, D. McDevitt, L. McFarlane, 1994, Clinical science.

C-type natriuretic peptide levels in cor pulmonale and in congestive heart failure.

B. Lipworth, A. Struthers, W. Coutie, 1994, Thorax.

Reversible myocardial ischaemia following vincristine containing chemotherapy.

B. Lipworth, A. Boyter, R. Cargill, 1994, Respiratory medicine.

Assessment of proximal pulmonary arterial stiffness using magnetic resonance imaging: effects of technique, age and exercise

B. Lipworth, A. Struthers, J. Weir-McCall, 2016, BMJ Open Respiratory Research.

University of Dundee Assessment of proximal pulmonary arterial stiffness using magnetic resonance imaging

B. Lipworth, A. Struthers, J. Weir-McCall, 2016 .

C-reactive protein. A clinical marker in community-acquired pneumonia.

B. Lipworth, I. Cree, E. Spiers, 1995, Chest.

Anti-interleukin 13 for asthma: stick or twist?

B. Lipworth, S. Jabbal, C. Kuo, 2018, The Lancet. Respiratory medicine.

C-reactive protein in simple community-acquired pneumonia.

B. Lipworth, R. P. Smith, Robin P. Smith, 1995, Chest.

Asthma prescribing according to Arg16Gly beta-2 genotype: a randomised trial in adolescents

B. Lipworth, C. Palmer, Christina J. Jones, 2021, European Respiratory Journal.

Optimised glucocorticoid therapy: the sharpening of an old spear

B. Lipworth, G. Burmester, F. Buttgereit, 2005, The Lancet.

Influence of sex-steroid hormones on the regulation of lymphocyte beta 2-adrenoceptors during the menstrual cycle.

B. Lipworth, J. A. Peters, N. Wheeldon, 1994, British journal of clinical pharmacology.

Scottish consensus statement on the role of FeNO in adult asthma.

J. Haughney, B. Lipworth, M. Spears, 2019, Respiratory medicine.

In vivo effect of albuterol on methacholine-contracted bronchi in conjunction with salmeterol and formoterol.

B. Lipworth, I. Aziz, 1999, The Journal of allergy and clinical immunology.

Effects of low dose fluticasone/salmeterol combination on surrogate inflammatory markers in moderate persistent asthma

B. Lipworth, F. Carey, G. Currie, 2003, Allergy.

Effects of fluticasone vs. fluticasone/salmeterol on airway calibre and airway hyperresponsiveness in mild persistent asthma.

B. Lipworth, G. Currie, Suvi Stenback, 2003, British journal of clinical pharmacology.

Leukotriene antagonists in asthma.

C. Jackson, B. Lipworth, 2011, The New England journal of medicine.

Dose-response comparison of budesonide dry powder inhalers using adenosine monophosphate bronchial challenge.

B. Lipworth, E. Sims, S. Das, 2005, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Leukotriene C4 synthase polymorphisms and responsiveness to leukotriene antagonists in asthma.

B. Lipworth, J. Sylvester, J. Lima, 2003, British journal of clinical pharmacology.

Effects of montelukast on surrogate inflammatory markers in corticosteroid-treated patients with asthma.

B. Lipworth, G. Currie, Daniel K. C. Lee, 2003, American journal of respiratory and critical care medicine.

Evaluation of surrogate inflammatory markers for optimizing inhaled corticosteroid therapy in a real-life clinical setting

B. Lipworth, S. Fowler, F. Carey, 2003 .

Airway and systemic effects of hydrofluoroalkane fluticasone and beclomethasone in patients with asthma

B. Lipworth, S. Fowler, A. Wilson, 2002, Thorax.

Therapeutic ratio of hydrofluoroalkane and chlorofluorocarbon formulations of fluticasone propionate.

B. Lipworth, S. Fowler, E. Sims, 2002, Chest.

Effects of monotherapy with intra‐nasal corticosteroid or combined oral histamine and leukotriene receptor antagonists in seasonal allergic rhinitis

B. Lipworth, E. Sims, A. Wilson, 2001, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

A retrospective cohort study to evaluate the relationship of airway hyperresponsiveness to type 2 biomarkers in persistent asthma

B. Lipworth, R. Chan, C. Kuo, 2021, Archives of Asthma, Allergy and Immunology.

Supervised step-down of inhaled corticosteroids in the community--an observational study.

C. Jackson, B. Lipworth, P. Williamson, 2011, Respiratory medicine.

Effects of chlorine and exercise on the unified airway in adolescent elite Scottish swimmers

B. Lipworth, P. Williamson, K. Clearie, 2010, Allergy.

A proof-of-concept study to evaluate the antiinflammatory effects of a novel soluble cyclodextrin formulation of nebulized budesonide in patients with mild to moderate asthma.

B. Lipworth, P. Williamson, A. Tutuncu, 2009, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Adenosine monophosphate bronchial provocation and the actions of asthma therapy

B. Lipworth, R. Gray, D. K. C. Lee, 2003, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Relationship of skin‐prick reactivity to aeroallergens and hyperresponsiveness to challenges with methacholine and adenosine monophosphate

B. Lipworth, S. Fowler, 2003, Allergy.

Screening for bronchial hyperresponsiveness using methacholine and adenosine monophosphate. Relationship to asthma severity and beta(2)-receptor genotype.

B. Lipworth, S. Fowler, O. J. Dempsey, 2000, American journal of respiratory and critical care medicine.

Effects of single or combined histamine H1-receptor and leukotriene CysLT1-receptor antagonism on nasal adenosine monophosphate challenge in persistent allergic rhinitis.

C. Jackson, B. Lipworth, Daniel K. C. Lee, 2004, British journal of clinical pharmacology.

Emerging role of antileukotriene therapy in allergic rhinitis

B. Lipworth, 2001, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Influence of β(2)-adrenergic receptor polymorphism on methacholine hyperresponsiveness in asthmatic patients.

B. Lipworth, A. Manoharan, W. Anderson, 2013, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

THE ARGININE 16 BETA2 ADRENOCEPTOR GENOTYPE PREDISPOSES ASTHMATICS TAKING REGULAR SALMETEROL TO INCREASED EXACERBATIONS

B. Lipworth, C. Palmer, S. Mukhopadhyay, 2006 .

THE ARGININE16 BETA2 ADRENOCEPTOR GENOTYPE PREDISPOSES TO EXACERBATIONS IN YOUNG ASTHMATICS TAKING REGULAR SALMETEROL

B. Lipworth, C. Palmer, S. Mukhopadhyay, 2006 .

Inhaled and systemic corticosteroid response in severe asthma assessed by alveolar nitric oxide: a randomized crossover pilot study of add-on therapy.

B. Lipworth, P. Williamson, S. Vaidyanathan, 2013, British journal of clinical pharmacology.

Antagonism of long‐acting β2‐adrenoceptor agonism

B. Lipworth, 2002 .

β2-Adrenergic receptor Gly16Arg polymorphism and impaired asthma control in corticosteroid-treated asthmatic adults.

B. Lipworth, A. Manoharan, Joseph Lipworth, 2015, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Reply: Pharmacological obfuscation of clinical relevance.

B. Lipworth, P. Williamson, P. Short, 2014, American journal of respiratory and critical care medicine.

β-Adrenoceptor genotype and bronchoprotective subsensitivity with long-acting β-agonists in asthma.

B. Lipworth, 2013, American journal of respiratory and critical care medicine.

Step-up therapy for children with uncontrolled asthma.

B. Lipworth, C. Palmer, S. Mukhopadhyay, 2010, The New England journal of medicine.

β-agonist safety and the elephant in the room?

B. Lipworth, P. Williamson, C. Palmer, 2010, Thorax.

The arginine-16 beta2-adrenoceptor polymorphism predisposes to bronchoprotective subsensitivity in patients treated with formoterol and salmeterol.

I. Hall, B. Lipworth, J. Lima, 2003, British journal of clinical pharmacology.

Effects of treatment with formoterol on bronchoprotection against methacholine.

B. Lipworth, D. Hendrick, M. Devlin, 1998, The American journal of medicine.

Benefit-Risk Assessment of Long-Acting β2-Agonists in Asthma

C. Jackson, B. Lipworth, 2004 .

Asthma exacerbations and sputum eosinophil counts. Authors' reply

B. Lipworth, C. Brightling, A. Wardlaw, 2003 .

Systemic IL-6 and Severe Asthma

B. Lipworth, R. Chan, C. Kuo, 2020, American journal of respiratory and critical care medicine.

Allergen sensitization and bronchial hyper‐responsiveness to adenosine monophosphate in asthmatic patients

C. Jackson, B. Lipworth, G. Currie, 2003, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Omalizumab or dupilumab for chronic rhinosinusitis with nasal polyposis.

B. Lipworth, R. Chan, C. Kuo, 2020, The Journal of allergy and clinical immunology.

Dupilumab for nasal polyposis

B. Lipworth, R. Chan, C. Kuo, 2020, The Lancet.

Debate on long-acting β agonists for asthma: they think it's all over.

B. Lipworth, S. Jabbal, 2017, The Lancet. Respiratory medicine.

Use of the oral beta blocker bisoprolol to reduce the rate of exacerbation in people with chronic obstructive pulmonary disease (COPD): a randomised controlled trial (BICS)

D. Price, J. Wedzicha, A. Morice, 2022, Trials.

Erratum to: Comparative lung bioavailability of fluticasone/salmeterol via a breath-actuated spacer and conventional plastic spacers

B. Lipworth, P. Williamson, A. Nair, 2011, European Journal of Clinical Pharmacology.

Are we overlooking persistent small airways dysfunction in community-managed asthma?

B. Lipworth, W. Anderson, E. Zajda, 2012, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Proof of concept study to evaluate step-down therapy with inhaled corticosteroid alone or additive therapy on surrogate inflammatory markers in asthma.

B. Lipworth, P. Williamson, P. Short, 2011, British journal of clinical pharmacology.

Respirable dose delivery of fluticasone propionate from a small valved holding chamber, a compact breath actuated integrated vortex device and a metered dose inhaler.

B. Lipworth, A. Nair, D. Menzies, 2008, British journal of clinical pharmacology.

Pharmacokinetics and extrapulmonary beta 2 adrenoceptor activity of nebulised racemic salbutamol and its R and S isomers in healthy volunteers.

B. Lipworth, C. Arbeeny, D. Clark, 1997, Thorax.

Comparison of combination inhalers vs inhaled corticosteroids alone in moderate persistent asthma.

C. Jackson, B. Lipworth, G. Currie, 2003, British journal of clinical pharmacology.

The step 3 dilemma for moderate persistent asthma.

B. Lipworth, 2002, American journal of respiratory and critical care medicine.

The emerging role of leukotriene antagonists in asthma therapy.

B. Lipworth, 1999, Chest.

Leukotriene-receptor antagonists

B. Lipworth, 1999, The Lancet.

Combined mediator blockade or topical steroid for treating the unified allergic airway

B. Lipworth, A. Wilson, D. Menzies, 2007, Allergy.

Comparative adrenal suppression with inhaled budesonide and fluticasone propionate in adult asthmatic patients.

B. Lipworth, D. Clark, A. Grove, 1996, Thorax.

Effects of intranasal salmeterol and fluticasone given alone and in combination in persistent allergic rhinitis.

B. Lipworth, A. Nair, P. Short, 2012, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Fluticasone reverses oxymetazoline-induced tachyphylaxis of response and rebound congestion.

B. Lipworth, F. Khan, P. Williamson, 2010, American journal of respiratory and critical care medicine.

Effects of butterbur treatment in intermittent allergic rhinitis: a placebo-controlled evaluation.

B. Lipworth, Daniel K. C. Lee, K. Haggart, 2004, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Effects of intranasal corticosteroids on adrenal, bone, and blood markers of systemic activity in allergic rhinitis.

B. Lipworth, A. Wilson, E. Sims, 1998, The Journal of allergy and clinical immunology.

Salmeterol and tolerance.

C. Jackson, B. Lipworth, 2000, Chest.

Clinical pharmacology of corticosteroids in bronchial asthma.

B. Lipworth, 1993, Pharmacology & therapeutics.

Pharmacokinetic/pharmacodynamic evaluation of urinary cortisol suppression after inhalation of fluticasone propionate and mometasone furoate.

B. Lipworth, G. Hochhaus, Daniel K. C. Lee, 2007, British journal of clinical pharmacology.

Effects of topical corticosteroid and combined mediator blockade on domiciliary and laboratory measurements of nasal function in seasonal allergic rhinitis.

B. Lipworth, A. Wilson, E. Sims, 2001, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Antiasthmatic effects of mediator blockade versus topical corticosteroids in allergic rhinitis and asthma.

B. Lipworth, A. Wilson, O. J. Dempsey, 2000, American journal of respiratory and critical care medicine.

Modern drug treatment of chronic asthma

B. Lipworth, 1999, BMJ.

Adrenal suppression with inhaled budesonide and fluticasone propionate given by large volume spacer to asthmatic children.

B. Lipworth, R. Clark, D. Clark, 1996, Thorax.

A comparison of the systemic bioactivity of inhaled budesonide and fluticasone propionate in normal subjects.

B. Lipworth, C. Jackson, L. McFarlane, 1994, British journal of clinical pharmacology.

COVID-19: Start with the nose

B. Lipworth, R. Chan, Chris RuiWen Kuo, 2020, Journal of Allergy and Clinical Immunology.

Weathering the Cytokine Storm in Susceptible Patients with Severe SARS-CoV-2 Infection

B. Lipworth, S. Lipworth, R. Chan, 2020, The Journal of Allergy and Clinical Immunology: In Practice.

Paradoxical down-regulation and desensitization of beta2-adrenoceptors by exogenous progesterone in female asthmatics.

B. Lipworth, K. Tan, L. McFarlane, 1997, Chest.

Asthma Step-Down Strategies: Perhaps the Patient Should Decide?

E. Israel, B. Lipworth, 2018, The journal of allergy and clinical immunology. In practice.

Airway subsensitivity with long-acting beta 2-agonists. Is there cause for concern?

B. Lipworth, 1997, Drug safety.

Long-acting β2-adrenoceptor agonists: a smart choice for asthma?

B. Lipworth, 2007 .

Evaluation of an abbreviated adenosine monophosphate bronchial challenge.

B. Lipworth, T. Fardon, M. Hodge, 2005, Chest.

Disconnect between effects of mepolizumab on severe eosinophilic asthma and chronic rhinosinusitis with nasal polyps.

B. Lipworth, R. Chan, C. Kuo, 2020, The journal of allergy and clinical immunology. In practice.

Effects of methacholine challenge on alveolar nitric oxide

B. Lipworth, P. Williamson, K. Clearie, 2009, Thorax.

Real-life small airway outcomes in severe asthma patients receiving biologic therapies.

B. Lipworth, R. Chan, Chris RuiWen Kuo, 2021, The journal of allergy and clinical immunology. In practice.

Criteria for Airway Oscillometry Reversibility in Asthma.

B. Lipworth, R. Chan, C. Kuo, 2020, Chest.

Inhaled triple therapy and airway hyperresponsiveness in persistent asthma.

B. Lipworth, S. Jabbal, R. Chan, 2021, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Effects of prior treatment with salmeterol and formoterol on airway and systemic beta 2 responses to fenoterol.

B. Lipworth, A. Grove, 1996, Thorax.

Airway and systemic effects of inhaled corticosteroids in asthma: dose response relationship.

B. Lipworth, 1996, Pulmonary pharmacology.

A bolus of inhaled budesonide rapidly reverses airway subsensitivity and beta2-adrenoceptor down-regulation after regular inhaled formoterol.

B. Lipworth, I. Aziz, 1999, Chest.

Making simple things complicated using anti-inflammatory reliever therapy

B. Lipworth, R. Chan, C. Kuo, 2020, European Respiratory Journal.

Inhaled 2-adrenoceptor agonists in asthma: help or hindrance?

B. Lipworth, D. McDevitt, 2006 .

Expression of the beta 2 adrenoceptor partial agonist/antagonist activity of salbutamol in states of low and high adrenergic tone.

B. Lipworth, L. McFarlane, A. Grove, 1995, Thorax.

Effects of theophylline on airway eosinophils.

B. Lipworth, 2002, American journal of respiratory and critical care medicine.

Electrocardiographic changes induced by inhaled salbutamol after treatment with bendrofluazide: effects of replacement therapy with potassium, magnesium and triamterene.

B. Lipworth, A. Struthers, D. McDevitt, 1990, Clinical science.

Subsensitivity of bronchodilator and systemic beta 2 adrenoceptor responses after regular twice daily treatment with eformoterol dry powder in asthmatic patients.

B. Lipworth, D. McDevitt, D. Newnham, 1995, Thorax.

The effects of angiotensin II on circulating levels of natriuretic peptides.

B. Lipworth, W. Coutie, R. Cargill, 1994, British journal of clinical pharmacology.

Clinical Pharmacokinetics of Drugs Administered Buccally and Sublingually

B. Lipworth, J. Motwani, 1991, Clinical pharmacokinetics.

Long-acting beta2-agonists in asthma: not so SMART?

B. Lipworth, G. Currie, Daniel K. C. Lee, 2006, Drug safety.

Un-diagnosing persistent adult asthma

B. Lipworth, S. Jabbal, 2017, European Respiratory Journal.

Effects of Extra-Fine Inhaled and Oral Corticosteroids on Alveolar Nitric Oxide in COPD

B. Lipworth, P. Williamson, P. Short, 2012, Lung.

P257 Effects of extra-fine inhaled and oral corticosteroids on alveolar nitric oxide in COPD

B. Lipworth, P. Williamson, P. Short, 2011, Thorax.

Concomitant administration of low-dose prednisolone protects against in vivo beta2-adrenoceptor subsensitivity induced by regular formoterol.

B. Lipworth, K. Tan, L. McFarlane, 1998, Chest.

Dose Response to Inhaled Corticosteroids: Benefits and Risks

B. Lipworth, Andrew Wilson, A. Wilson, 1998 .

Tadalafil in patients with chronic obstructive pulmonary disease: a randomised, double-blind, parallel-group, placebo-controlled trial.

B. Lipworth, A. Struthers, P. Hopkinson, 2014, The Lancet. Respiratory medicine.

Comparison of hypokalaemic, electrocardiographic and haemodynamic responses to inhaled isoprenaline and salbutamol in young and elderly subjects

B. Lipworth, D. McDevitt, B. Tregaskis, 2004, European Journal of Clinical Pharmacology.

A comparison of the effects of prednisolone and mianserin on ventilatory, exercise and psychometric parameters in patients with chronic obstructive pulmonary disease

B. Lipworth, D. Dhillon, R. Clark, 2004, European Journal of Clinical Pharmacology.

Salmeterol in smokers with COPD.

B. Lipworth, 1996, Thorax.

Bronchodilator reversibility to low and high doses of terbutaline and ipratropium bromide in patients with chronic obstructive pulmonary disease.

B. Lipworth, D. Dhillon, R. Clark, 1993, Thorax.

Pharmacological management—oral treatment

B. Lipworth, G. Currie, Daniel K. C. Lee, 2006, BMJ : British Medical Journal.

Phosphodiesterase type 4 inhibitors for asthma: a real breakthrough or just expensive theophylline?

B. Lipworth, 2006, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Investigations on the renin-angiotensin system in acute severe asthma.

N. Thomson, B. Lipworth, C. McSharry, 1997, The European respiratory journal.

Determinants of airway hyperresponsiveness in mild asthma.

C. Jackson, B. Lipworth, G. Currie, 2003, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

The ISOLDE trial

B. Lipworth, 2000, BMJ : British Medical Journal.

Lack of subsensitivity to albuterol after treatment with salmeterol in patients with asthma.

B. Lipworth, C. Jackson, 1999, American journal of respiratory and critical care medicine.

Current appraisal of single inhaler triple therapy in COPD

B. Lipworth, S. Jabbal, C. Kuo, 2018, International journal of chronic obstructive pulmonary disease.

An evaluation of short-term corticosteroid response in perennial allergic rhinitis using histamine and adenosine monophosphate nasal challenge.

B. Lipworth, E. Sims, F. Robb, 2003, British journal of clinical pharmacology.

Reproducibility of nasal function measurements with histamine and adenosine monophosphate nasal challenge testing in patients with allergic rhinitis

B. Lipworth, E. Sims, F. Robb, 2003 .

A comparison of once daily fexofenadine versus the combination of montelukast plus loratadine on domiciliary nasal peak flow and symptoms in seasonal allergic rhinitis

B. Lipworth, A. Wilson, E. Sims, 2002, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Subjective and objective markers of treatment response in patients with seasonal allergic rhinitis.

B. Lipworth, A. Wilson, O. J. Dempsey, 2000, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Safety of Inhaled and Intranasal Corticosteroids

C. Jackson, B. Lipworth, 2000, Drug safety.

Dose–response for inhaled fluticasone on airway and systemic inflammation in COPD

B. Lipworth, P. Williamson, K. Clearie, 2011, European Respiratory Journal.

Beta2-adrenoceptor regulation and function in female asthmatic patients receiving the oral combined contraceptive pill.

B. Lipworth, K. Tan, L. McFarlane, 1998, Chest.

Effects of exogenous female sex-steroid hormones on lymphocyte beta 2-adrenoceptors in normal females.

B. Lipworth, K. Tan, L. McFarlane, 1996, British journal of clinical pharmacology.

Sex Hormones and Asthma: Don’t Forget Progesterone

B. Lipworth, R. Chan, C. Kuo, 2020, American journal of respiratory and critical care medicine.

Antagonism of long-acting beta2-adrenoceptor agonism.

B. Lipworth, 2002, British journal of clinical pharmacology.

Tolerance with beta 2-adrenoceptor agonists: time for reappraisal.

B. Lipworth, A. Grove, B. Lipworth, 1995, British journal of clinical pharmacology.

COPD_A_229794 99..106

F. Martinez, K. Rabe, B. Lipworth, 2020 .

Concomitant inhaled corticosteroid resensitises cardiac β2-adrenoceptors in the presence of long-acting β2-agonist therapy

B. Lipworth, I. Aziz, L. McFarlane, 1998, European Journal of Clinical Pharmacology.

Montelukast and Churg-Strauss syndrome.

B. Lipworth, A. Wilson, 2001, Thorax.

On-demand relief treatment for asthma

B. Lipworth, S. Fowler, G. Currie, 2001, The Lancet.

Hypoxaemia and release of endothelin-1.

B. Lipworth, D. Kiely, R. Clark, 1995, Thorax.

Extrapulmonary β2-responses to intravenous salbutamol during the menstrual cycle

B. Lipworth, D. McDevitt, D. Newnham, 2004, European Journal of Clinical Pharmacology.

Effects of hydrofluoroalkane formulations of ciclesonide 400 microg once daily vs fluticasone 250 microg twice daily on methacholine hyper-responsiveness in mild-to-moderate persistent asthma.

B. Lipworth, G. Currie, Daniel K. C. Lee, 2004, British journal of clinical pharmacology.

Effects of hydroﬂuoroalkane formulations of ciclesonide 400 m g once daily vs ﬂuticasone 250 m g twice daily on methacholine hyper-responsiveness in mild-to-moderate persistent asthma

B. Lipworth, Daniel K. C. Lee, K. Haggart, 2004 .

Acute Effects of Anp and Bnp on Hypoxic Pulmonary Vasoconstriction in Humans

B. Lipworth, R. Cargill, 1995 .

Comparative efficacy and anti-inflammatory profile of once-daily therapy with leukotriene antagonist or low-dose inhaled corticosteroid in patients with mild persistent asthma.

B. Lipworth, O. J. Dempsey, G. Kennedy, 2002, The Journal of allergy and clinical immunology.

Effects of fluticasone plus salmeterol versus twice the dose of fluticasone in asthmatic patients

C. Jackson, B. Lipworth, G. Currie, 2003, European Journal of Clinical Pharmacology.

Therapeutic ratio of inhaled fluticasone

B. Lipworth, 2000, Thorax.

Effects of hypercapnia on hemodynamic, inotropic, lusitropic, and electrophysiologic indices in humans.

B. Lipworth, D. Kiely, R. Cargill, 1996, Chest.

Systemic versus topical glucocorticoid therapy for acute asthma.

B. Lipworth, D. Menzies, 2005, American journal of respiratory and critical care medicine.

Reappraisal of the clinical effect of mepolizumab.

B. Lipworth, S. Jabbal, 2017, The Lancet. Respiratory medicine.

In vivo comparison of the relative systemic bioavailability of fluticasone propionate from three anti-static spacers and a metered dose inhaler.

B. Lipworth, A. Nair, D. Menzies, 2009, British journal of clinical pharmacology.

Dose-response to salbutamol via a novel palm sized nebuliser (Aerodose Inhaler), conventional nebuliser (Pari LC Plus) and metered dose inhaler (Ventolin Evohaler) in moderate to severe asthmatics.

B. Lipworth, E. Sims, R. Fishman, 2005, British journal of clinical pharmacology.

Emerging Pharmacotherapy for Covid-19

B. Lipworth, R. Chan, C. Kuo, 2020, The journal of the Royal College of Physicians of Edinburgh.

Comparative cutoff points for adenosine monophosphate and methacholine challenge testing.

B. Lipworth, T. Fardon, M. Hodge, 2004, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Differences in lung bioavailability between different propellants for fluticasone propionate

B. Lipworth, E. Sims, A. Wilson, 1999, The Lancet.

Sensitivity of Lung Resistance and Compliance to Beta-Blocker Induced Bronchoconstriction and Long Acting Beta-Agonist Withdrawal in COPD

B. Lipworth, S. Jabbal, 2017, Lung.

Development and implementation of guidelines in allergic rhinitis – an ARIA-GA2LEN paper.

B. Yawn, W. Busse, H. Schünemann, 2010, Allergy.

The comparative safety/efficacy ratio of HFA-BDP.

B. Lipworth, 2000, Respiratory medicine.

Evaluation of an antibiotic prescribing protocol for treatment of acute exacerbations of chronic obstructive airways disease in a hospital respiratory unit.

B. Lipworth, P. Davey, R. Clark, 1995, The Journal of antimicrobial chemotherapy.

Benefits of long-acting β2-agonists

B. Lipworth, 2007 .

Combination therapy with a long-acting beta2-agonist and an inhaled corticosteroid as initial maintenance treatment in asthma.

B. Lipworth, G. Currie, Daniel K. C. Lee, 2005, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Airway and systemic effects of hydrofluoroalkane formulations of high-dose ciclesonide and fluticasone in moderate persistent asthma.

B. Lipworth, Daniel K. C. Lee, L. McFarlane, 2005, Chest.

Effects of high-dose inhaled fluticasone propionate on the hypothalamic-pituitary-adrenal axis in asthmatic patients with severely impaired lung function.

B. Lipworth, G. Currie, Daniel K. C. Lee, 2004, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Repeated dosing effects of mediator antagonists in inhaled corticosteroid-treated atopic asthmatic patients.

C. Jackson, B. Lipworth, Daniel K. C. Lee, 2004, Chest.

Butterbur, a herbal remedy, confers complementary anti‐inflammatory activity in asthmatic patients receiving inhaled corticosteroids

B. Lipworth, K. Haggart, F. Robb, 2004 .

RAPID RESPONSES FROM BMJ.COM: Anti-inflammatory end points

B. Lipworth, S. Fowler, G. Currie, 2002, British medical journal.

Comparison of rhinitis treatments using MASK‐air® data and considering the minimal important difference

H. Schünemann, T. Zuberbier, J. Brożek, 2022, Allergy.

Systemic safety of fluticasone furoate/vilanterol combination

B. Lipworth, 2013, Thorax.

Adrenal suppression with chronic dosing of fluticasone propionate compared with budesonide in adult asthmatic patients.

B. Lipworth, D. Clark, 1997, Thorax.

Clinical importance of the Step 3 choice in asthma

B. Lipworth, M. Weatherall, M. Masoli, 2006, Thorax.

Bronchodilator response to albuterol after regular formoterol and effects of acute corticosteroid administration.

B. Lipworth, I. Aziz, 2000, Chest.

Duration of steroid therapy determines dose-response effect.

B. Lipworth, 2002, Chest.

Optimizing inhaled drug delivery in patients with asthma.

C. Jackson, B. Lipworth, 1995, The British journal of general practice : the journal of the Royal College of General Practitioners.

Influence of β2-adrenoceptor 16 genotype on propranolol-induced bronchoconstriction in patients with persistent asthma.

B. Lipworth, A. Manoharan, P. Short, 2014, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Relationships Between Airway Hyperresponsiveness, Inflammation, and Calibre in Asthma

B. Lipworth, S. Lipworth, P. Short, 2011, Lung.

Single Triple vs Dual Inhaler Therapy.

B. Lipworth, C. Kuo, 2019, Chest.

Cardiac effects of the 3-adrenoceptor agonist BRL35135 in

B. Lipworth, N. Wheeldon, D. McDevitt, 2006 .

Evaluation of in vivo partial 31 / 2-agonist activity : a dose-ranging study with carteolol

B. Lipworth, N. Wheeldon, D. McDevitt, 2006 .

The effects of time and dose on the relative 1- and 2-adrenoceptor antagonism of betaxolol and atenolol

B. Lipworth, N. Irvine, D. G. McDEVITF, 2006 .

A dose-ranging study to evaluate the β1-adrenoceptor selectivity of bisoprolol

B. Lipworth, D. McDevitt, N. Irvine, 1991, European Journal of Clinical Pharmacology.

Selectivity of antagonist and partial agonist activity of celiprolol in normal subjects.

B. Lipworth, D. McDevitt, N. Wheeldon, 1992, British journal of clinical pharmacology.

Evaluation of in vivo partial beta 1/beta 2-agonist activity: a dose-ranging study with carteolol.

B. Lipworth, D. McDevitt, N. Wheeldon, 1992, British journal of clinical pharmacology.

Beta-adrenoceptor responses to inhaled salbutamol in the elderly.

B. Lipworth, D. McDevitt, B. Tregaskis, 1989, British journal of clinical pharmacology.

Airway-systemic ratio of hydrofluoroalkane fluticasone and beclomethasone in asthmatics

B. Lipworth, S. Fowler, E. Sims, 2002 .

Adrenocortical activity with repeated administration of one-daily inhaled fluticasone propionate and budesonide in asthmatic adults

B. Lipworth, A. Wilson, M. Devlin, 1998, European Journal of Clinical Pharmacology.

Adrenocortical activity with repeated twice daily dosing of fluticasone propionate and budesonide given via a large volume spacer to asthmatic school children.

B. Lipworth, L. McFarlane, D. Clark, 1997, Thorax.

Eosinophils and airway hyper-responsiveness

B. Lipworth, 2001, The Lancet.

Of mice and men-the curious tale of β blockers in asthma.

B. Lipworth, S. Jabbal, 2016, The Lancet. Respiratory medicine.

From mouse to man: predicting biased effects of beta‐blockers in asthma

B. Lipworth, P. Short, W. Anderson, 2016, British journal of pharmacology.

Benefit-risk assessment of long-acting beta2-agonists in asthma.

C. Jackson, B. Lipworth, 2004, Drug safety.

Lung delivery of salbutamol given by breath activated pressurized aerosol and dry powder inhaler devices.

B. Lipworth, D. Clark, 1997, Pulmonary pharmacology & therapeutics.

Effect of multiple actuations, delayed inhalation and antistatic treatment on the lung bioavailability of salbutamol via a spacer device.

B. Lipworth, D. Clark, 1996, Thorax.

A placebo‐controlled evaluation of butterbur and fexofenadine on objective and subjective outcomes in perennial allergic rhinitis

B. Lipworth, F. Robb, R. Gray, 2004, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Allergic inflammation in the unified airway: start with the nose

B. Lipworth, P. White, 2000, Thorax.

Behavioural patterns in allergic rhinitis medication in Europe: A study using MASK‐air® real‐world data

T. Zuberbier, Á. Cruz, W. Fokkens, 2022, Allergy.

Comparable efficacy of administration with face mask or mouthpiece of nebulized budesonide suspension for infants and young children with persistant asthma.

B. Lipworth, C. Jackson, 2001, American journal of respiratory and critical care medicine.

Measures for detecting systemic bioactivity with inhaled and intranasal corticosteroids.

B. Lipworth, J. Seckl, 1997, Thorax.

Cardiopulmonary interactions of salbutamol and hypoxaemia in healthy young volunteers.

B. Lipworth, D. Kiely, R. Cargill, 1995, British journal of clinical pharmacology.

Respiratory symptoms, pulmonary function, and markers of inflammation among bar workers before and after a legislative ban on smoking in public places.

Martyn Barnes, Brian J Lipworth, B. Lipworth, 2006, JAMA.

Pneumothorax resulting from bronchial brushing during fibre-optic bronchoscopy.

B. Lipworth, R. P. Smith, 1994, Respiratory medicine.

Sex differences in hypokalaemic and electrocardiographic effects of inhaled terbutaline.

B. Lipworth, A. Struthers, D. McDevitt, 1992, Thorax.

Aspirin desensitisation therapy for aspirin-intolerant chronic rhinosinusitis

B. Lipworth, S. Mckean, S. Vaidyanathan, 2009 .

Aspirin desensitisation therapy for aspirin-intolerant chronic rhinosinusitis

B. Lipworth, S. Vaidyanathan, S. Mckean, 2009 .

Montelukast protects against nasal lysine-aspirin challenge in patients with aspirin-induced asthma

B. Lipworth, K. Haggart, F. Robb, 2004, European Respiratory Journal.

Montelukast protects against nasal lysine-aspirin challenge in patients with aspirin-induced asthma.

B. Lipworth, K. Haggart, F. Robb, 2004, The European respiratory journal.

Therapeutic implications of non-genomic glucocorticoid activity

B. Lipworth, 2000, The Lancet.

Evaluation of the buccal component of systemic absorption with inhaled fluticasone propionate

B. Lipworth, O. J. Dempsey, W. Coutie, 1999, Thorax.

24 hour and fractionated profiles of adrenocortical activity in asthmatic patients receiving inhaled and intranasal corticosteroids

B. Lipworth, A. Wilson, 1999, Thorax.

Correction to: Benefit:Risk Profile of Budesonide in Obstructive Airways Disease

B. Lipworth, D. Tashkin, R. Brattsand, 2019, Drugs.

Beta2-adrenoceptor polymorphism and bronchoprotective sensitivity with regular short- and long-acting beta2-agonist therapy.

I. Hall, A. Wheatley, B. Lipworth, 1999, Clinical science.

Uncorrected nitric oxide levels in mild asthmatics produce flawed interpretation.

B. Lipworth, 2013, The Journal of allergy and clinical immunology.

The effects of butterbur on the histamine and allergen cutaneous response.

C. Jackson, B. Lipworth, Daniel K. C. Lee, 2004, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Effects of mediator antagonism on mannitol and adenosine monophosphate challenges

S. Anderson, B. Lipworth, J. Brannan, 2003, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Combined mediator blockade or topical corticosteroids for seasonal allergic rhinitis.

B. Lipworth, G. Currie, Daniel K. C. Lee, 2002, The Journal of allergy and clinical immunology.

Evaluation of the beta 2 adrenoceptor agonist/antagonist activity of formoterol and salmeterol.

B. Lipworth, A. Grove, 1996, Thorax.

Bronchodilator reversibility to albuterol predicts bronchodilator response to salmeterol.

C. Jackson, B. Lipworth, 2002, Chest.

P10 Randomised Placebo Controlled Trial to Evaluate Chronic Dosing Effects of Propranolol in Steroid Treated Persistent Asthmatics

B. Lipworth, P. Williamson, P. Short, 2012, Thorax.

Inhaled Corticosteroids and COVID-19

B. Lipworth, S. Lipworth, R. Chan, 2020, American journal of respiratory and critical care medicine.

A high dose of albuterol does not overcome bronchoprotective subsensitivity in asthmatic subjects receiving regular salmeterol or formoterol.

B. Lipworth, I. Aziz, 2011, The Journal of allergy and clinical immunology.

Comparison of parameters of in vitro lymphocyte β2-adrenoceptor function in normal and asthmatic subjects

B. Lipworth, W. Coutie, D. Newnham, 2004, European Journal of Clinical Pharmacology.

Subsensitivity of beta-adrenoceptor responses in asthmatic patients taking regular low dose inhaled salbutamol

B. Lipworth, D. Dhillon, D. McDevitt, 2004, European Journal of Clinical Pharmacology.

Effect of β blockers in treatment of chronic obstructive pulmonary disease: a retrospective cohort study

Brian J Lipworth, B. Lipworth, S. Lipworth, 2011, BMJ : British Medical Journal.

The effects of chronic dosing on the beta 1 and beta 2-adrenoceptor antagonism of betaxolol and atenolol.

B. Lipworth, D. McDevitt, N. Irvine, 1991, European journal of clinical pharmacology.

A dose-ranging study to evaluate the beta 1-adrenoceptor selectivity of bisoprolol.

B. Lipworth, D. McDevitt, N. Irvine, 1991, European journal of clinical pharmacology.

Prospective follow-up of novel markers of bone turnover in persistent asthmatics exposed to low and high doses of inhaled ciclesonide over 12 months.

B. Lipworth, L. McFarlane, W. Anderson, 2012, The Journal of clinical endocrinology and metabolism.

Enhanced synergy between fluticasone propionate and salmeterol inhaled from a single inhaler versus separate inhalers.

B. Lipworth, T. Fardon, 2004, The Journal of allergy and clinical immunology.

Comparative trough effects of formoterol and salmeterol on lymphocyte β2-adrenoceptor – regulation and bronchodilatation

B. Lipworth, L. McFarlane, I. Aziz, 1999, European Journal of Clinical Pharmacology.

Comparative effects of atrial natriuretic peptide and brain natriuretic peptide on the aldosterone and pressor responses to angiotensin II in man.

B. Lipworth, A. Struthers, R. Cargill, 1995, Clinical science.

Asthma management with HFA-BDP (Qvar).

B. Lipworth, C. Leach, R. Davies, 1999, Hospital medicine.

Fenoterol and asthma mortality

C. Jackson, B. Lipworth, 1998, The Lancet.

Dose-response for adrenal suppression with hydrofluoroalkane formulations of fluticasone propionate and beclomethasone dipropionate.

B. Lipworth, S. Fowler, A. Wilson, 2001, British journal of clinical pharmacology.

Equivalence of hydrofluoroalkane (HFA) and chlorofluorocarbons (CFC) formulations of inhaled beclomethasone.

B. Lipworth, C. Jackson, 2000, Respiratory medicine.

Pharmacokinetics of chlorofluorocarbon and hydrofluoroalkane metered-dose inhaler formulations of beclomethasone dipropionate.

B. Lipworth, C. Jackson, 1999, British journal of clinical pharmacology.

Exercise-induced asthma [1] (multiple letters)

E. R. Mcfadden, B. Lipworth, J. Jenkins, 1998 .

Abnormal myocardial repolarisation in response to hypoxaemia and fenoterol.

B. Lipworth, A. Struthers, D. Kiely, 1995, Thorax.

Lung bioavailability of chlorofluorocarbon free, dry powder and chlorofluorocarbon containing formulations of salbutamol.

B. Lipworth, D. Clark, 1996, British journal of clinical pharmacology.

Blood eosinophils: The forgotten man of inhaled steroid dose titration

B. Lipworth, S. Jabbal, Brian Lipworth, 2018, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

P172 Fluticasone/salmeterol combination confers significant benefits in smoking asthmatics

B. Lipworth, P. Williamson, P. Hopkinson, 2010, Thorax.

Relationship of Mannitol Challenge to Methacholine Challenge and Inflammatory Markers in Persistent Asthmatics Receiving Inhaled Corticosteroids

B. Lipworth, W. Anderson, 2012, Lung.

Short-term repeatability and correlates of laboratory measures of nasal function in patients with seasonal allergic rhinitis.

B. Lipworth, E. Sims, Q. Gardiner, 2002, Rhinology.

Profound vagal reactions to brain natriuretic peptide

B. Lipworth, T. MacDonald, P. Clarkson, 1995, Journal of Molecular Medicine.

Systemic effects of fluticasone on blood eosinophils in bronchiectasis

B. Lipworth, R. Chan, C. Kuo, 2020, European Respiratory Journal.

Systemic potency of fluticasone in asthma

B. Lipworth, R. Chan, C. Kuo, 2020, European Respiratory Journal.

Adrenal suppression with inhaled corticosteroids: the seed and the soil.

B. Lipworth, S. Jabbal, C. Kuo, 2018, The Lancet. Respiratory medicine.

Designer inhaled corticosteroids: are they any safer?

B. Lipworth, 2005, Chest.

Adrenal suppression with inhaled corticosteroids.

B. Lipworth, 2001, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Mometason furoate levels.

B. Lipworth, 2001, Chest.

The problem of dose-response and therapeutic ratio of inhaled steroids.

B. Lipworth, 2001, American journal of respiratory and critical care medicine.

Fluticasone and cortisol measurements.

B. Lipworth, 2001, Chest.

Systemic e V ects of inhaled steroids

B. Lipworth, S. Bell, K. Stallard, 2001 .

Relative effects of exogenous inhaled corticosteroids on diurnal cortisol secretion.

B. Lipworth, 2000, Archives of internal medicine.

Inhaled corticosteroids and bone density

B. Lipworth, 2000, The Lancet.

Effects of oral and inhaled corticosteroids on the hypothalamic-pituitary-adrenal axis.

B. Lipworth, C. Jackson, 1999, The Journal of allergy and clinical immunology.

Dose-response comparison of systemic bioactivity with inhaled budesonide and triamcinolone acetonide in asthmatic adults.

B. Lipworth, A. Wilson, A. Wilson, 1998, The Journal of allergy and clinical immunology.

Dose-response effect for adrenal suppression with repeated twice daily inhaled fluticasone propionate and triamcinolone acetonide in adult asthmatics.

B. Lipworth, A. Wilson, L. McFarlane, 1997, American journal of respiratory and critical care medicine.

High-dose inhaled steroids in asthmatic children

B. Lipworth, D. Clark, 1996, The Lancet.

Effects of short-term exposure to high-dose inhaled corticosteroids on novel markers of bone metabolism

B. Lipworth, L. McFarlane, C. Jackson, 1996, European Journal of Clinical Pharmacology.

Intravenous montelukast in acute asthma: expensive aminophylline?

B. Lipworth, O. J. Dempsey, 2000, Thorax.

Lower thresholds for bronchial challenge testing

B. Lipworth, G. Currie, Daniel K. C. Lee, 2004, Allergy.

Single and short-term dosing effects of levocetirizine on adenosine monophosphate bronchoprovocation in atopic asthma.

B. Lipworth, Daniel K. C. Lee, F. Robb, 2004, British journal of clinical pharmacology.

Comparison of measured exhaled nitric oxide at varying flow rates

B. Lipworth, D. Menzies, T. Fardon, 2005, Thorax.

Comparative in vivo bioactivity of modern H1-antihistamines on AMP challenge in atopic asthma.

B. Lipworth, G. Currie, Daniel K. C. Lee, 2003, The Journal of allergy and clinical immunology.

Single dose and steady-state pharmacokinetics of 4 mg and 8 mg oral salbutamol controlled-release in patients with bronchial asthma

M. Charter, B. Lipworth, J. Palmer, 1989, European Journal of Clinical Pharmacology.

Comparison of the efficacy and systemic effects of 4 mg and 8 mg formulations of salbutamol controlled release in patients with asthma

B. Lipworth, J. Palmer, D. Dhillon, 2004, European Journal of Clinical Pharmacology.

Short-term dose-response relationships for the relative systemic effects of oral prednisolone and inhaled fluticasone in asthmatic adults.

B. Lipworth, A. Wilson, 1999, British journal of clinical pharmacology.

Does size really matter?: Relationship of particle size to lung deposition and exhaled fraction.

B. Lipworth, S. Jabbal, G. Poli, 2017, The Journal of allergy and clinical immunology.

Systemic bioavailability of fluticasone in COPD.

B. Lipworth, D. Menzies, 2005, American journal of respiratory and critical care medicine.

Evaluation of partial β‐adrenoceptor agonist activity

B. Lipworth, A. Grove, 1997 .

Eosinophils from patients with asthma express higher levels of the pan‐leucocyte receptor CD45 and the isoform CD45RO

B. Lipworth, O. J. Dempsey, G. Walsh, 2003, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Evaluation of corticotropin releasing factor stimulation and basal markers of hypothalamic-pituitary-adrenal axis suppression in asthmatic patients.

B. Lipworth, D. Clark, 1997, Chest.

Comparative lung bioavailability of fluticasone/salmeterol via a breath-actuated spacer and conventional plastic spacers

B. Lipworth, P. Williamson, A. Nair, 2010, European Journal of Clinical Pharmacology.

Lung delivery of non-CFC salbutamol via small volume metal spacer and large volume plastic spacer devices compared with an open vent jet nebulizer.

B. Lipworth, D. Clark, 1998, British journal of clinical pharmacology.

Asthma exacerbations and inhaled corticosteroids

B. Lipworth, T. Fardon, R. Gray, 2004, The Lancet.

Montelukast for persistent asthma

B. Lipworth, S. Fowler, G. Currie, 2001, The Lancet.

Bronchoprotection with formoterol via dry powder and metered-dose inhalers in patients with asthma.

A. Morice, B. Lipworth, B. O'connor, 2005, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Therapeutic equivalence of inhaled salbutamol

B. Lipworth, S. Fowler, 2000, Thorax.

Systemic beta-adrenoceptor responses to salbutamol given by metered-dose inhaler alone and with pear shaped spacer attachment: comparison of electrocardiographic, hypokalaemic and haemodynamic effects.

B. Lipworth, A. Struthers, D. McDevitt, 1989, British journal of clinical pharmacology.

Effect of exogenous female sex-steroid hormones on β2-adrenoceptors in healthy males

B. Lipworth, K. Tan, L. McFarlane, 1997, European Journal of Clinical Pharmacology.

Comparative effects of desloratadine, fexofenadine, and levocetirizine on nasal adenosine monophosphate challenge in patients with perennial allergic rhinitis

B. Lipworth, K. Haggart, D. K. C. Lee, 2004, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Pneumonia Due to Inhaled Corticosteroids in COPD.

B. Lipworth, R. Chan, C. Kuo, 2020, Chest.

Salmeterol and conventional asthma therapy.

B. Lipworth, 2001, Chest.

Prior Treatment with Diuretic Augments the Hypokalaemic and Electrocardiographic Effects of Inhaled Salbutamol in Man

B. Lipworth, A. Struthers, D. McDevitt, 1989 .

Nitric oxide: an important role in the maintenance of systemic and pulmonary vascular tone in man.

B. Lipworth, A. Struthers, D. Kiely, 1998, British journal of clinical pharmacology.

Use of Pulsed-Wave Doppler Echocardiography to Measure Changes in MPAP: To the Editor

B. Lipworth, D. Kiely, 1997 .

Human C-type natriuretic peptide: effects on the haemodynamic and endocrine responses to angiotensin II.

B. Lipworth, A. Struthers, R. Cargill, 1995, Cardiovascular research.

The effects of enalapril and spironolactone on terbutaline-induced hypokalemia.

B. Lipworth, A. Struthers, D. McDevitt, 1992, Chest.

Corticosteroid Protection Against COVID-19: Begin with the Nose

B. Lipworth, T. Carr, R. Chan, 2021, The Journal of Allergy and Clinical Immunology: In Practice.

β-agonists and asthma

B. Lipworth, E. Walters, H. Booth, 1993, The Lancet.

Tocilizumab for severe COVID-19 pneumonia

B. Lipworth, R. Chan, C. Kuo, 2020, The Lancet Rheumatology.

Predicting Severe Outcomes in COVID-19

B. Lipworth, R. Chan, C. Kuo, 2020, The Journal of Allergy and Clinical Immunology: In Practice.

Journal Pre-proof Elevated levels of interleukin-6 and CRP predict the need for mechanical ventilation in COVID-19

B. Lipworth, T. Weinberger, T. Herold, 2020 .

Use of inhaled corticosteroids in asthma and coronavirus disease 2019

B. Lipworth, R. Chan, C. Kuo, 2020, Annals of Allergy, Asthma & Immunology.

Effects of inhaled fluticasone propionate and oral prednisolone on lymphocyte beta 2-adrenoceptor function in asthmatic patients.

B. Lipworth, K. Tan, L. McFarlane, 1996, Chest.

β2-agonists in asthma

A. Morice, B. Lipworth, J. Crane, 1991, The Lancet.

Relationship of large and small airway response with inhaled corticosteroid to asthma control.

B. Lipworth, A. Manoharan, W. Anderson, 2013, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Congenital nephrotic syndrome and agammaglobulinemia: A therapeutic

B. Lipworth, A. Manoharan, W. Anderson, 2013 .

Montelukast confers complimentary non-steroidal anti-inflammatory activity in asthmatics receiving fluticasone alone and fluticasone/salmeterol combination

B. Lipworth, G. Currie, K. Haggart, 2003 .

Long-Acting β2 Agonists and Inhaled Corticosteroids in Asthma

B. Lipworth, 2009 .

Bronchoprotective tolerance with inhaled corticosteroid/long-acting β-agonist treatment.

B. Lipworth, Chris RuiWen Kuo, 2019, The Journal of allergy and clinical immunology.

Acute effects of ANP and BNP on hypoxic pulmonary vasoconstriction in humans.

B. Lipworth, R. Cargill, R. I. Cargill, 1995, British journal of clinical pharmacology.

Clinical pharmacology of 3-adrenoceptors

B. Lipworth, 2003 .

Impact of Biologic Therapy on the Small Airways Asthma Phenotype

B. Lipworth, R. Chan, 2022, Lung.

Importance of drug-device interaction in determining systemic effects of inhaled cor ticosteroids

B. Lipworth, O. J. Dempsey, E. Sims, 1999, The Lancet.

Adrenal suppression with high doses of inhaled fluticasone propionate and triamcinolone acetonide in healthy volunteers

B. Lipworth, A. Wilson, L. McFarlane, 1997, European Journal of Clinical Pharmacology.

An evaluation of short-term corticosteroid response in perennial allergic rhinitis using histamine and adenosine monophosphate nasal challenge.

B. Lipworth, E. Sims, F. Robb, 2003, British journal of clinical pharmacology.

Does use or withdrawal of long-acting β2-adrenoceptor induce desensitisation?

I. Hall, B. Lipworth, K. Tan, 1998, The Lancet.

Bronchodilation subsensitivity to salbutamol after salmeterol

B. Lipworth, M. Weinberger, N. Barnes, 1995, The Lancet.

Asthma control

B. Lipworth, C. Connolly, A. Grove, 1994, The Lancet.

Nasal nitric oxide as a measure of osteomeatal complex patency in nasal polyps.

B. Lipworth, P. Williamson, S. Vaidyanathan, 2011, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Dose response with fluticasone propionate on adrenocortical activity and recovery of basal and stimulated responses after stopping treatment

B. Lipworth, A. Wilson, E. Sims, 1999, Clinical endocrinology.

Evaluating the effects of "triple therapy" with inhaled corticosteroids, long-acting beta2-agonists, and leukotriene modifiers in asthma.

B. Lipworth, G. Currie, Daniel K. C. Lee, 2006, Chest.

Lost in the labyrinth of end points.

B. Lipworth, 2001, Chest.

P215 Left Ventricular Hypertrophy in Chronic Obstructive Pulmonary Disease Without Hypoxaemia: The Elephant in the Room?

B. Lipworth, A. Struthers, J. George, 2012, Thorax.

Lisinopril attenuates acute hypoxic pulmonary vasoconstriction in humans.

B. Lipworth, R. Cargill, R. I. Cargill, 1996, Chest.

Effects of once-daily formoterol and budesonide given alone or in combination on surrogate inflammatory markers in asthmatic adults.

B. Lipworth, A. Wilson, I. Aziz, 2000, Chest.

Peak inspiratory flow rate is more sensitive than acoustic rhinometry or rhinomanometry in detecting corticosteroid response with nasal histamine challenge.

B. Lipworth, E. Sims, F. Robb, 2003, Rhinology.

Biomarkers to predict inhaled corticosteroid response.

B. Lipworth, 2015, The Journal of allergy and clinical immunology.

Non-canonical β2-receptor signaling.

B. Lipworth, R. Chan, Chris RuiWen Kuo, 2019, The Journal of allergy and clinical immunology.

Butterbur, a herbal remedy, attenuates adenosine monophosphate induced nasal responsiveness in seasonal allergic rhinitis

C. Jackson, B. Lipworth, G. Currie, 2003, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Which is better for fall in nitric oxide?

B. Lipworth, 2002, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Effects of repeated once daily dosing of three intranasal corticosteroids on basal and dynamic measures of hypothalamic-pituitary-adrenal-axis activity.

B. Lipworth, A. Wilson, L. McFarlane, 1998, The Journal of allergy and clinical immunology.

Marginal benefits of adding formoterol

B. Lipworth, C. Jackson, 2002, Thorax.

Nebulised salbutamol and magnesium sulphate in acute asthma

B. Lipworth, Daniel K. C. Lee, C. Jackson, 2003, The Lancet.

Budesonide dose-response in mild persistent asthma.

B. Lipworth, 2002, American journal of respiratory and critical care medicine.

Differences in asthma control and lung function in relation to allergic status

B. Lipworth, C. Kuo, 2019, European Respiratory Journal.

Childhood asthma exacerbations and the Arg16 β2-receptor polymorphism: A meta-analysis stratified by treatment.

E. Burchard, M. Pino-Yanes, B. Lipworth, 2016, The Journal of allergy and clinical immunology.

Bioavailability of salbutamol.

B. Lipworth, A. Grove, 1994, Thorax.

Effects of Short Term Exposure to Inhaled Corticosteroids on Novel Biochemical Markers of Bone Metabolism

B. Lipworth, L. McFarlane, A. Grove, 1995 .

Clinical relevance of house dust mite immunotherapy.

B. Lipworth, 2015, The Journal of allergy and clinical immunology.

Allergic burden and response to dupilumab.

B. Lipworth, R. Chan, C. Kuo, 2020, The journal of allergy and clinical immunology. In practice.

Spacer devices increase dose of inhaled corticosteroids delivered

B. Lipworth, A. Wilson, O. J. Dempsey, 1999, BMJ.

Acute neurohormonal responses to hypoxaemia in man

B. Lipworth, W. Coutie, L. McFarlane, 2004, European Journal of Applied Physiology and Occupational Physiology.

Adrenal insufficiency in patients taking benralizumab as corticosteroid sparing therapy.

B. Lipworth, R. Chan, R. Misirovs, 2021, The Lancet. Respiratory medicine.

End‐point selection to determine the airway‐systemic ratio of inhaled corticosteroids in asthma

B. Lipworth, R. Chan, C. Kuo, 2020, British journal of clinical pharmacology.

Inhaled triple therapy in chronic obstructive pulmonary disease

B. Lipworth, S. Jabbal, C. Kuo, 2018, The Lancet.

Cardioprotective effects of inhaled corticosteroid-containing combination therapy in COPD

B. Lipworth, C. Kuo, 2019, European Respiratory Journal.

Salmeterol response and β2-adrenergic receptor genotype

C. Jackson, B. Lipworth, 2007 .

Benefits of combination therapy on exacerbations in nonsmoking patients with asthma.

C. Jackson, B. Lipworth, 2008, The Journal of allergy and clinical immunology.

Portable exhaled nitric oxide measurement: Comparison with the "gold standard" technique.

B. Lipworth, A. Nair, D. Menzies, 2007, Chest.

Effects of oral and inhaled corticosteroid on lymphocyte beta2-adrenoceptor function in asthmatic patients.

B. Lipworth, K. Tan, L. McFarlane, 2003, British journal of clinical pharmacology.

Reduced protection against exercise induced bronchoconstriction after chronic dosing with salmeterol.

B. Lipworth, I. Cree, D. Dhillon, 1994, Respiratory medicine.

Importance of β2-receptor function in premenstrual asthma.

B. Lipworth, R. Chan, Kirsten E. Stewart, 2022, The journal of allergy and clinical immunology. In practice.

The skin vasoconstrictor assay does not correlate significantly to airway or systemic responsiveness to inhaled budesonide in asthmatic patients

B. Lipworth, E. Sims, W. Coutie, 2003, European Journal of Clinical Pharmacology.

Adrenal suppression with fluticasone furoate.

B. Lipworth, 2013, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Low-Grade B Cell Lymphoproliferative Disorder Masquerading as Chronic Rhinosinusitis

B. Lipworth, R. Chan, C. Kuo, 2021, Sinusitis.

PHARMACOKINETICS AND DISPOSITION

B. Lipworth, D. Clark, 1997 .

Inhaled corticosteroid dose-response on blood eosinophils in asthma.

B. Lipworth, S. Jabbal, A. Manoharan, 2016, The Lancet. Respiratory medicine.

Effects of salmeterol on smooth muscle versus inflammatory outcomes.

C. Jackson, B. Lipworth, 2003, The Journal of allergy and clinical immunology.

Effect of plastic spacer handling on salbutamol lung deposition in asthmatic children.

H. Bisgaard, J. Anhøj, B. Lipworth, 2002, British journal of clinical pharmacology.

Effect of electrostatic charge in plastic spacers on the lung delivery of HFA-salbutamol in children.

H. Bisgaard, J. Anhøj, B. Lipworth, 1999, British journal of clinical pharmacology.

Pharmacokinetics, efficacy and adverse effects of sublingual salbutamol in Patients with asthma

B. Lipworth, T. Moreland, A. Struthers, 1989, European Journal of Clinical Pharmacology.

Real‐world data using mHealth apps in rhinitis, rhinosinusitis and their multimorbidities

T. Zuberbier, Á. Cruz, S. Durham, 2022, Clinical and translational allergy.

Utility of impulse oscillometry in patients with moderate to severe persistent asthma.

B. Lipworth, S. Jabbal, A. Manoharan, 2016, The Journal of allergy and clinical immunology.

Allergic Rhinitis and its Impact on Asthma (ARIA): achievements in 10 years and future needs.

Todor A Popov, D. Postma, A. Sheikh, 2012, The Journal of allergy and clinical immunology.

New perspectives on inhaled drug delivery and systemic bioactivity.

B. Lipworth, 1995, Thorax.

Therapeutic equivalence of inhaled salbutamol (multiple letters)

B. Lipworth, S. Fowler, 2000 .

What can we learn about COPD from impulse oscillometry?

B. Lipworth, S. Jabbal, 2018, Respiratory medicine.

Is diet partly responsible for differences in COVID-19 death rates between and within countries?

Ana C. Coelho, Todor A Popov, I. Pavord, 2020, Clinical and Translational Allergy.

Phosphodiesterase-4 inhibitors for asthma and chronic obstructive pulmonary disease

B. Lipworth, 2005, The Lancet.

Elevated levels of IL-6 and CRP predict the need for mechanical ventilation in COVID-19

B. Lipworth, M. von Bergwelt-Baildon, T. Weinberger, 2020, Journal of Allergy and Clinical Immunology.

Systemic bioactivity profiles of oral prednisolone and nebulized budesonide in adult asthmatics.

B. Lipworth, A. Wilson, L. McFarlane, 1998, Chest.

β2-Adrenoceptor polymorphism and bronchoprotective sensitivity with regular short- and long-acting β2-agonist therapy

I. Hall, A. Wheatley, B. Lipworth, 1999 .

Pharmacokinetics of inhaled drugs.

B. Lipworth, B J Lipworth, 2003, British journal of clinical pharmacology.

MACVIA‐ARIA Sentinel NetworK for allergic rhinitis (MASK‐rhinitis): the new generation guideline implementation

F. Rodenas, G. Joos, R. Bourret, 2015, Allergy.

Guidance to 2018 good practice: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma

A. Sheikh, O. Mayora, T. To, 2019, Clinical and Translational Allergy.

Allergic Rhinitis and its Impact on Asthma (ARIA) Phase 4 (2018): Change management in allergic rhinitis and asthma multimorbidity using mobile technology.

A. Sheikh, O. Mayora, T. To, 2019, The Journal of allergy and clinical immunology.

ARIA 2016: Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle

Todor A Popov, D. Postma, A. Sheikh, 2016, Clinical and Translational Allergy.

Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5)

D. Postma, I. Pavord, A. Sheikh, 2016, Clinical and Translational Allergy.

Severe Chronic Allergic (and Related) Diseases: A Uniform Approach – A MeDALL – GA2LEN – ARIA Position Paper

D. Postma, C. Auffray, A. Sheikh, 2012, International Archives of Allergy and Immunology.

Differentiation of COVID‐19 signs and symptoms from allergic rhinitis and common cold: An ARIA‐EAACI‐GA2LEN consensus

Todor A Popov, J. Bousquet, T. Zuberbier, 2021, Allergy.

Removing nasal valve obstruction in peak nasal inspiratory flow measurement.

B. Lipworth, M. Barnes, 2007, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Investigation of putative cardiac δ3-adrenoceptors in man

B. Lipworth, D. McDevitt, N. Wheeldon, 1993 .

The effects of lower than conventional doses of oral nadolol on relative beta 1/beta 2-adrenoceptor blockade.

B. Lipworth, D. McDevitt, N. Wheeldon, 1994, British Journal of Clinical Pharmacology.

Effects of hydrocortisone on acute β-adrenoceptor blocker and histamine induced bronchoconstriction.

B. Lipworth, P. Williamson, P. Short, 2012, British journal of clinical pharmacology.

Respiratory effect of beta-blockers in people with asthma and cardiovascular disease: population-based nested case control study

P. Donnan, C. Jackson, B. Lipworth, 2017, BMC Medicine.

Adverse respiratory effect of acute β-blocker exposure in asthma: a systematic review and meta-analysis of randomized controlled trials.

Bruce Guthrie, Brian J Lipworth, P. Donnan, 2014, Chest.

Effects of intravenous and oral β-blockade in persistent asthmatics controlled on inhaled corticosteroids

B. Lipworth, P. Williamson, P. Short, 2013, Heart.

Arginine-16 β2 adrenoceptor genotype predisposes to exacerbations in young asthmatics taking regular salmeterol

B. Lipworth, C. Palmer, S. Mukhopadhyay, 2006, Thorax.

The effect of β2‐adrenoceptor haplotypes on bronchial hyper‐responsiveness in patients with asthma

I. Hall, B. Lipworth, A. Wilson, 2006, Allergy.

Left ventricular systolic performance during acute hypoxemia.

B. Lipworth, D. Kiely, R. I. Cargill, 1995, Chest.

Nrf2-interacting nutrients and COVID-19: time for research to develop adaptation strategies

Ana C. Coelho, Todor A Popov, I. Pavord, 2020, Clinical and Translational Allergy.

Asthma and Cushing's syndrome.

B. Lipworth, R. Jung, A. Wilson, 2000, Chest.

Toll‐like receptor 3 blockade in rhinovirus‐induced experimental asthma exacerbations: A randomized controlled study

V. Backer, S. Johnston, B. Lipworth, 2017, The Journal of allergy and clinical immunology.

A Repeat Audit of Hospital Discharge Letters in Patients Admitted with Acute Asthma

B. Lipworth, D. Dhillon, R. Clark, 1993 .

IMPLICATION OF ALTERNATIVE MINIMAL CLINICALLY IMPORTANT DIFFERENCE THRESHOLD ESTIMATION METHODS ON TECHNOLOGY ASSESSMENT

B. Lipworth, E. Meltzer, U. Munzel, 2016, International Journal of Technology Assessment in Health Care.

The minimal clinically important difference in allergic rhinitis

B. Lipworth, P. Williamson, S. Vaidyanathan, 2010, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Research priorities to address the global burden of chronic obstructive pulmonary disease (COPD) in the next decade

J. Wedzicha, D. Mannino, F. Martinez, 2021, Journal of global health.

Cardiopulmonary interactions with beta-blockers and inhaled therapy in COPD

B. Lipworth, S. Jabbal, A. Manoharan, 2017, QJM : monthly journal of the Association of Physicians.

Beta-blockers in COPD: time for reappraisal

J. Wedzicha, B. Lipworth, J. Vestbo, 2016, European Respiratory Journal.

Acute systemic effects of inhaled salbutamol in asthmatic subjects expressing common homozygous beta2-adrenoceptor haplotypes at positions 16 and 27.

B. Lipworth, Daniel K. C. Lee, C. E. Bates, 2003, British journal of clinical pharmacology.

Treatment of Chronic Rhinosinusitis With Nasal Polyposis With Oral Steroids Followed by Topical Steroids

P. Donnan, B. Lipworth, P. Williamson, 2011, Annals of Internal Medicine.

Nasal AMP and histamine challenge within and outside the pollen season in patients with seasonal allergic rhinitis.

B. Lipworth, P. Williamson, S. Vaidyanathan, 2011, The Journal of allergy and clinical immunology.

Haemodynamic and endocrine effects of type 1 angiotensin II receptor blockade in patients with hypoxaemic cor pulmonale.

B. Lipworth, D. Kiely, W. Coutie, 1997, Cardiovascular research.

Angiotensin II receptor blockade and effects on pulmonary hemodynamics and hypoxic pulmonary vasoconstriction in humans.

B. Lipworth, D. Kiely, R. Cargill, 1996, Chest.

Nebuliser performance, pharmacokinetics, airways and systemic effects of salbutamol given via a novel nebuliser delivery system ("Ventstream").

B. Lipworth, D. Newnham, D. Newnham, 1994, Thorax.

Correction to: Is diet partly responsible for differences in COVID-19 death rates between and within countries?

Ana C. Coelho, Todor A Popov, I. Pavord, 2020, Clinical and Translational Allergy.

Childhood asthma exacerbations and the Arg 16 2-receptor polymorphism

E. Burchard, M. Pino-Yanes, B. Lipworth, 2015 .

Functional antagonism with formoterol and salmeterol in asthmatic patients expressing the homozygous glycine-16 beta(2)-adrenoceptor polymorphism.

B. Lipworth, O. J. Dempsey, I. Aziz, 2000, Chest.

Airway Subsensitivity with Long-Acting β2-Agonists

B. Lipworth, 1997 .

Airway-stabilizing effect of long-acting beta2-agonists as add-on therapy to inhaled corticosteroids.

B. Lipworth, S. Ogston, G. Currie, 2003, QJM : monthly journal of the Association of Physicians.

Step-down therapy with low-dose fluticasone-salmeterol combination or medium-dose hydrofluoroalkane 134a-beclomethasone alone.

B. Lipworth, S. Fowler, G. Currie, 2002, The Journal of allergy and clinical immunology.

Effect of ciclesonide and fluticasone on hypothalamic-pituitary-adrenal axis function in adults with mild-to-moderate persistent asthma.

M. Kaliner, B. Lipworth, H. Kaiser, 2005, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Systemic corticosteriod rapidly reverses bronchodilator subsensitivity induced by formoterol in asthmatic patients.

I. Hall, B. Lipworth, K. Tan, 1997, American journal of respiratory and critical care medicine.

Relationship Between Changes in Quality of Life and Measures of Lung Function and Bronchial Hyper-Responsiveness During High-Dose Inhaled Corticosteroid Treatment in Uncontrolled Asthma

B. Lipworth, S. Fowler, L. C. Orr, 2003, American journal of respiratory medicine : drugs, devices, and other interventions.

Pharmacokinetic and pharmacodynamic comparison of hydrofluoroalkane and chlorofluorocarbon formulations of budesonide.

B. Lipworth, P. Williamson, M. Carlholm, 2011, British journal of clinical pharmacology.

Fluticasone propionate bioavailability in asthma

B. Lipworth, S. Fowler, A. Wilson, 2000, The Lancet.

Evaluation of the effect of a large volume spacer on the systemic bioactivity of fluticasone propionate metered-dose inhaler.

B. Lipworth, A. Wilson, O. J. Dempsey, 1999, Chest.

Inhaled corticosteroid dose response using domiciliary exhaled nitric oxide in persistent asthma: the FENOtype trial.

B. Lipworth, P. Williamson, P. Short, 2012, Chest.

Decongestant effects of nasal xylometazoline and mometasone furoate in persistent allergic rhinitis.

B. Lipworth, B. T. Biallosterski, T. Fardon, 2005, Rhinology.

Proof-of-concept evaluation of trough airway hyper-responsiveness following regular racemic or levosalbutamol in genotype-stratified steroid-treated persistent asthmatic patients.

B. Lipworth, C. Palmer, P. Williamson, 2014, Clinical science.

Effects of leukotriene receptor antagonist therapy in patients with chronic rhinosinusitis in a real life rhinology clinic setting.

B. Lipworth, A. Wilson, Q. Gardiner, 2001, Rhinology.

Underuse of β-blockers in heart failure and chronic obstructive pulmonary disease

D. Price, B. Lipworth, V. Carter, 2016, Heart.

The role of the renin-angiotensin and natriuretic peptide systems in the pulmonary vasculature.

B. Lipworth, R. I. Cargill, BJ Lipworth, 1995, British journal of clinical pharmacology.

Comparative effects of angiotensin II on Doppler parameters of left and right heart systolic and diastolic blood flow.

B. Lipworth, K. Dagg, 1993, British journal of clinical pharmacology.

Bronchoprotective effects of leukotriene receptor antagonists in asthma: a meta-analysis.

B. Lipworth, G. Currie, 2002, Chest.

The role of pulmonary arterial stiffness in COPD

B. Lipworth, A. Struthers, J. Weir-McCall, 2015, Respiratory medicine.

Paradoxical trough effects of triple therapy with budesonide/formoterol and tiotropium bromide on pulmonary function outcomes in COPD.

B. Lipworth, P. Williamson, S. Vaidyanathan, 2010, Chest.

Inhaled treatment for chronic obstructive pulmonary disease: what's new and how does it fit?

B. Lipworth, G. Currie, 2016, QJM : monthly journal of the Association of Physicians.

Beta2-adrenoceptor regulation and bronchodilator sensitivity after regular treatment with formoterol in subjects with stable asthma.

I. Hall, B. Lipworth, I. Aziz, 1998, The Journal of allergy and clinical immunology.

Bronchodilator subsensitivity to salbutamol after twice daily salmeterol in asthmatic patients

B. Lipworth, A Grove, B. J Lipworth, 1995, The Lancet.

Disconnection of pulmonary and systemic arterial stiffness in COPD

B. Lipworth, A. Struthers, J. Weir-McCall, 2018, International journal of chronic obstructive pulmonary disease.

Disconnect between standardized field‐based testing and mannitol challenge in Scottish elite swimmers

B. Lipworth, P. Williamson, K. Clearie, 2009, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Development of persistent late onset asthma following treatment with captopril.

J. McMurray, B. Lipworth, A. Struthers, 1989, The European respiratory journal.

Resistance Heterogeneity and Small Airway Asthma Phenotype

B. Lipworth, C. Kuo, 2019, American journal of respiratory and critical care medicine.

Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler Improves Lung Function versus Monotherapies in GOLD Category A Patients with COPD: Pooled Data from the Phase III PINNACLE Studies

F. Martinez, K. Rabe, B. Lipworth, 2020, International journal of chronic obstructive pulmonary disease.

An algorithm recommendation for the pharmacological management of allergic rhinitis in the UK: a consensus statement from an expert panel

B. Lipworth, J. Schwarze, I. Small, 2017, npj Primary Care Respiratory Medicine.

University of Dundee An algorithm recommendation for the pharmacological management of allergic rhinitis in the UK

B. Lipworth, J. Schwarze, I. Small, 2017 .

The presence of emphysema does not affect the systemic bioactivity of inhaled fluticasone in severe chronic obstructive pulmonary disease.

B. Lipworth, Daniel K. C. Lee, 2004, British journal of clinical pharmacology.

Relationships between impulse oscillometry, spirometry and dyspnoea in COPD.

B. Lipworth, W. Anderson, 2012, The journal of the Royal College of Physicians of Edinburgh.

Type 2 Asthma Inflammation and COVID-19: A Double Edged Sword

B. Lipworth, R. Chan, Chris RuiWen Kuo, 2021, The Journal of Allergy and Clinical Immunology: In Practice.

Use of Fractional Exhaled Nitric Oxide to Guide the Treatment of Asthma: An Official American Thoracic Society Clinical Practice Guideline

B. Lipworth, C. Sorkness, L. Que, 2021, American journal of respiratory and critical care medicine.

Comparative safety and efficacy of 2 formulations of fluticasone aqueous nasal spray in persistent allergic rhinitis.

B. Lipworth, S. Vaidyanathan, M. Barnes, 2009, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Effect of exercise on the nasal transmucosal potential difference in patients with cystic fibrosis and normal subjects

B. Lipworth, A. Struthers, W. Coutie, 2022 .

The long-term sequelae of COVID-19: an international consensus on research priorities for patients with pre-existing and new-onset airways disease

D. Mannino, G. Koppelman, B. Lipworth, 2021, The Lancet Respiratory Medicine.

Effect of systemic steroids on humming nasal nitric oxide in chronic rhinosinusitis with nasal polyposis.

B. Lipworth, P. Williamson, S. Vaidyanathan, 2010, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Allopurinol in Patients with Pulmonary Hypertension Associated with Chronic Lung Disease

B. Lipworth, A. Struthers, J. Weir-McCall, 2020, International journal of chronic obstructive pulmonary disease.

COPD_A_260917 2015..2024

B. Lipworth, A. Struthers, J. Weir-McCall, 2020 .

Effect of fluticasone propionate nasal spray on the hypothalamic-pituitary-adrenal axis.

B. Lipworth, C. Jackson, 1999, The Journal of allergy and clinical immunology.

Clinical pharmacology of beta 3-adrenoceptors.

B. Lipworth, 1996, British journal of clinical pharmacology.

Effect of aspirin on airway inflammation and pulmonary function in patients with persistent asthma.

B. Lipworth, A. Nair, D. Menzies, 2008, The Journal of allergy and clinical immunology.

Effects of intranasal corticosteroid on nasal adenosine monophosphate challenge in persistent allergic rhinitis *

B. Lipworth, T. Fardon, M. L. Barnes, 2006, Allergy.

Pharmacologic and anti‐IgE treatment of allergic rhinitis ARIA update (in collaboration with GA2LEN)

R. Dubakiene, Todor A Popov, B. Yawn, 2006, Allergy.

Rhinitis associated with asthma is distinct from rhinitis alone: The ARIA‐MeDALL hypothesis

L. Boulet, O. Spranger, T. Haahtela, 2023, Allergy.

Unlocking the quiet zone: the small airway asthma phenotype.

B. Lipworth, A. Manoharan, W. Anderson, 2014, The Lancet. Respiratory medicine.

Comparative evaluation of nasal blood flow and airflow in the decongestant response to oxymetazoline.

B. Lipworth, P. Williamson, S. Vaidyanathan, 2012, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Effect of levocetirizine on nasal provocation testing with adenosine monophosphate compared with allergen challenge in allergic rhinitis

B. Lipworth, S. Vaidyanathan, A. Nair, 2009, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Gene-Environment Interaction in the Onset of Eczema in Infancy: Filaggrin Loss-of-Function Mutations Enhanced by Neonatal Cat Exposure

A. Woodcock, C. Pipper, K. Bønnelykke, 2008, PLoS medicine.

Acute hypoxic pulmonary vasoconstriction in man is attenuated by type I angiotensin II receptor blockade.

B. Lipworth, D. Kiely, R. Cargill, 1995, Cardiovascular research.

Hypoxaemia and the renin-angiotensin system: new answers for old questions.

B. Lipworth, D. Kiely, R. I. Cargill, 1994, Pulmonary pharmacology.

Oscillometry bronchodilator response in adult moderate to severe eosinophilic asthma patients: A prospective cohort study

B. Lipworth, R. Chan, 2022, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Is small airways dysfunction related to asthma control and type 2 inflammation?

B. Lipworth, S. Jabbal, C. Kuo, 2018, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Comparison of the effect of beclometasone/formoterol in asthma patients after methacholine‐induced bronchoconstriction: A noninferiority study using metered dose vs. dry powder inhaler

B. Lipworth, Dave Singh, L. Santoro, 2019, British journal of clinical pharmacology.

ARIA digital anamorphosis: Digital transformation of health and care in airway diseases from research to practice

Matteo Bonini, Daniel Laune, Boleslaw Samolinski, 2020, Allergy.

Do β3-adrenoceptors mediate metabolic responses to isoprenaline

B. Lipworth, N. Wheeldon, D. McDevitt, 1993 .

Steroid sparing effects of intranasal corticosteroids in asthma and allergic rhinitis

B. Lipworth, P. Williamson, S. Vaidyanathan, 2010, Allergy.

A proof‐of‐concept study to assess the putative dose response to topical corticosteroid in persistent allergic rhinitis using adenosine monophosphate challenge

B. Lipworth, A. Nair, D. Menzies, 2007, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Systemic bioactivity profiles of intranasal triamcinolone and mometasone in patients with perennial allergic rhinitis

B. Lipworth, E. Sims, G. Currie, 2003 .

Erratum to: Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5)

D. Postma, I. Pavord, A. Sheikh, 2017, Clinical and Translational Allergy.

The case for impulse oscillometry in the management of asthma in children and adults.

B. Lipworth, Hye-Won Shin, H. Komarow, 2017, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Clinical characteristics of the asthma bronchiectasis phenotype.

B. Lipworth, R. Chan, C. Duraikannu, 2022, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Have we reached our final destination with biologics in severe uncontrolled asthma?

B. Lipworth, R. Chan, 2023, The journal of allergy and clinical immunology. In practice.

Targeting downstream type 2 cytokines or upstream epithelial alarmins for severe asthma.

B. Lipworth, R. Chan, R. Misirovs, 2022, The journal of allergy and clinical immunology. In practice.

Improvements in asthma control and quality of life with benralizumab are unrelated to baseline bronchodilator response.

B. Lipworth, R. Chan, Kirsten E. Stewart, 2022, The journal of allergy and clinical immunology. In practice.

Inhaled corticosteroid dose response in asthma: Should we measure inflammation?

B. Lipworth, S. Jabbal, P. Short, 2017, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Does body mass index influence responsiveness to inhaled corticosteroids in persistent asthma?

B. Lipworth, W. Anderson, 2012, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Assessment of Small-Airways Disease Using Alveolar Nitric Oxide and Impulse Oscillometry in Asthma and COPD

B. Lipworth, P. Williamson, S. Vaidyanathan, 2011, Lung.

Asthma exacerbations and sputum eosinophil counts

Graeme P Currie, Daniel KC Lee, Brian J Lipworth, 2003, The Lancet.

Allergen immunotherapy in MASK‐air users in real‐life: Results of a Bayesian mixed‐effects model

T. Zuberbier, T. Casale, Á. Cruz, 2022, Clinical and translational allergy.

Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19: a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterisation Protocol UK

Jordan J. Clark, Michael J. Murphy, Megan L. Nagel, 2021, The Lancet. Respiratory medicine.

The ARIA approach of Value-Added Medicines: as-needed treatment in allergic rhinitis.

T. Zuberbier, Á. Cruz, T. Haahtela, 2022, The journal of allergy and clinical immunology. In practice.

after the ban provides strong evidence for reduced inhala- tion of secondhand smoke in the same period, as does the bar workers' self-reported estimate.

Daniel Menzies, Brian J. Lipworth, B. Lipworth, 2007 .

Safety and efficacy of the Russian COVID-19 vaccine: more information needed

Piero Carninci, B. Lipworth, L. Tuosto, 2020, The Lancet.

Long-acting beta2-adrenoceptor agonists: a smart choice for asthma?

B. Lipworth, 2007, Trends in pharmacological sciences.

Eosinophil paradox with mepolizumab in chronic rhinosinusitis with nasal polyposis.

B. Lipworth, R. Chan, Chris RuiWen Kuo, 2020, Journal of Allergy and Clinical Immunology.

Consistent trajectories of rhinitis control and treatment in 16,177 weeks: The MASK‐air® longitudinal study

T. Zuberbier, Á. Cruz, W. Fokkens, 2022, Allergy.

Effects of formoterol or salmeterol on impulse oscillometry in patients with persistent asthma.

B. Lipworth, A. Manoharan, A. Morrison, 2016, The Journal of allergy and clinical immunology.

Improved lung function and patient-reported outcomes with co-suspension delivery technology glycopyrrolate/formoterol fumarate metered dose inhaler in COPD: a randomized Phase III study conducted in Asia, Europe, and the USA

B. Lipworth, Rongchang Chen, N. Zhong, 2018, International journal of chronic obstructive pulmonary disease.

Human C-Type Natriuretic Peptide: Effects on the Haemodynamic and Hormonal Responses to Angiotensin Ii

B. Lipworth, A. Struthers, R. Cargill, 1995 .

Real-life effect of long-acting β2-agonist withdrawal in patients with controlled step 3 asthma.

B. Lipworth, S. Jabbal, A. Manoharan, 2016, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Tailored second-line therapy in asthmatic children with the Arg(16) genotype.

Colin N A Palmer, Brian J Lipworth, B. Lipworth, 2013, Clinical science.

Safety risks for patients with aspirin-exacerbated respiratory disease after acute exposure to selective nonsteroidal anti-inflammatory drugs and COX-2 inhibitors: Meta-analysis of controlled clinical trials.

P. Donnan, C. Jackson, B. Lipworth, 2014, The Journal of allergy and clinical immunology.

The inverse agonist propranolol confers no corticosteroid-sparing activity in mild-to-moderate persistent asthma.

B. Lipworth, P. Williamson, A. Manoharan, 2014, Clinical science.

Combined medical and surgical therapy for chronic rhinosinusitis with nasal polyposis.

B. Lipworth, R. Chan, R. Misirovs, 2022, The Lancet Respiratory Medicine.

MEASUREMENT OF NORMAL HUMAN AIRWAYS RESPONSE TO β‐ADRENOCEPTOR STIMULATION USING A FORCED OSCILLATION TECHNIQUE

B. Lipworth, D. McDevitt, R. Clark, 1991, Journal of clinical pharmacy and therapeutics.

Usefulness of impulse oscillometry for the assessment of airway hyperresponsiveness in mild-to-moderate adult asthma.

B. Lipworth, A. Manoharan, P. Short, 2015, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Sensitivity of impulse oscillometry and spirometry in beta-blocker induced bronchoconstriction and beta-agonist bronchodilatation in asthma.

B. Lipworth, P. Williamson, P. Short, 2012, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Effects of formoterol or salmeterol on impulse oscillometry in persistent asthma

B. Lipworth, A. Morrison, Alexander von Wilamowitz-Moellendorff, 2016 .

Filaggrin null mutations are associated with increased asthma exacerbations in children and young adults

B. Lipworth, C. Palmer, S. Mukhopadhyay, 2008, Allergy.

Vasoconstrictor effects of angiotensin II on the pulmonary vascular bed.

B. Lipworth, K. Dagg, K. Dagg, 1994, Chest.

The burden of chronic obstructive pulmonary disease associated with maintenance monotherapy in the UK

B. Lipworth, A. Scowcroft, Susan C Edwards, 2016, International journal of chronic obstructive pulmonary disease.

Combined oral and intranasal corticosteroid therapy for nasal polyps.

P. Donnan, B. Lipworth, P. Williamson, 2011, Annals of internal medicine.

The effect of pindolol on creatine kinase is not due to beta 2-adrenoceptor partial agonist activity.

B. Lipworth, D. McDevitt, D. Newnham, 1991, British journal of clinical pharmacology.

Effects of adding either a leukotriene receptor antagonist or low-dose theophylline to a low or medium dose of inhaled corticosteroid in patients with persistent asthma.

B. Lipworth, S. Fowler, O. J. Dempsey, 2002, Chest.

Acute effects of hypoxaemia and angiotensin II in the human pulmonary vascular bed.

B. Lipworth, R. Cargill, 1994, Pulmonary pharmacology.

Positioning the principles of precision medicine in care pathways for allergic rhinitis and chronic rhinosinusitis – A EUFOREA‐ARIA‐EPOS‐AIRWAYS ICP statement

D. Ryan, R. Picard, M. Kogevinas, 2017, Allergy.

Hypokalemic and ECG sequelae of combined beta-agonist/diuretic therapy. Protection by conventional doses of spironolactone but not triamterene.

B. Lipworth, A. Struthers, D. McDevitt, 1990, Chest.

MACVIA clinical decision algorithm in adolescents and adults with allergic rhinitis.

Todor A Popov, I. Pavord, A. Sheikh, 2016, The Journal of allergy and clinical immunology.

Eosinophil depletion with benralizumab is associated with attenuated mannitol airway hyperresponsiveness in severe uncontrolled eosinophilic asthma.

B. Lipworth, S. Jabbal, R. Chan, 2022, The Journal of allergy and clinical immunology.

Bisoprolol versus celiprolol on dynamic hyperinflation, cardiopulmonary exercise and domiciliary safety in COPD: a single-centre, randomised, crossover study

B. Lipworth, R. Ross, P. Short, 2023, BMJ Open Respiratory Research.

It is important to distinguish between HFrEF and HFpEF when interpreting these data

B. Lipworth, V. Carter, G. Devereux, 2016, Heart.

Improvements with sublingual house dust mite immunotherapy in allergic rhinitis.

B. Lipworth, 2016, Journal of Allergy and Clinical Immunology.

Comparative in vivo lung delivery of hydrofluoroalkane-salbutamol formulation via metered-dose inhaler alone, with plastic spacer, or with cardboard tube.

B. Lipworth, S. Fowler, A. Wilson, 2001, Chest.

Early lung absorption profile of non-CFC salbutamol via small and large volume plastic spacer devices.

B. Lipworth, D. Clark, 1998, British journal of clinical pharmacology.

Pharmacokinetics and systemic beta2-adrenoceptor-mediated responses to inhaled salbutamol.

B. Lipworth, S. Fowler, 2001, British journal of clinical pharmacology.

Butterbur, a herbal remedy, confers complementary anti-inflammatory activity in asthmatic patients receiving inhaled corticosteroids.

B. Lipworth, K. Haggart, F. Robb, 2004, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

MACVIA-ARIA Sentinel NetworK for allergic rhinitis (MASK-rhinitis): the new generation guideline implementation.

Todor A Popov, D. Postma, R. Picard, 2015, Allergy.

Severe Chronic Allergic (and Related) Diseases: A Uniform Approach – A MeDALL – GA2LEN – ARIA Position Paper

D. Postma, C. Auffray, W. Busse, 2012, International Archives of Allergy and Immunology.

Guidance to 2018 good practice: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma

O. Mayora, T. To, D. Caillaud, 2019, Clinical and Translational Allergy.

International collaborative research on Charcot's disease

B. Lipworth, P. Williamson, 2009 .

Acute hypoxic pulmonary vasoconstriction in man is attenuated by type I angiotensin II receptor blockade.

B. Lipworth, D. Kiely, R. I. Cargill, 1995, Cardiovascular research.

Effects of single or combined histamine H1-receptor and leukotriene CysLT1-receptor antagonism on nasal adenosine monophosphate challenge in persistent allergic rhinitis.

C. Jackson, B. Lipworth, Daniel K. C. Lee, 2004, British journal of clinical pharmacology.

A novel breath-actuated integrated vortex spacer device increases relative lung bioavailability of fluticasone/salmeterol in combination.

B. Lipworth, A. Nair, D. Menzies, 2009, Pulmonary pharmacology & therapeutics.

Respiratory effect of beta-blocker eye drops in asthma: population-based study and meta-analysis of clinical trials.

P. Donnan, C. Jackson, B. Lipworth, 2016, British journal of clinical pharmacology.

Medium-term repeatability for airwave oscillometry in patients with severe asthma taking benralizumab

B. Lipworth, R. Chan, 2023, The journal of allergy and clinical immunology. Global.

Clinical Investigations: InfectionC-Reactive Protein: A Clinical Marker in Community-Acquired Pneumonia

B. Lipworth, I. Cree, E. Spiers, 1995 .

Letter to the editor: Comparing pace and speed in the pulmonary circulation?

B. Lipworth, A. Struthers, J. Weir-McCall, 2016, American journal of physiology. Heart and circulatory physiology.

Tailored second-line therapy in asthmatic children with the Arg(16) genotype.

B. Lipworth, S. Ogston, S. Mukhopadhyay, 2013, Clinical science.

Arginine-16 β2 adrenoceptor genotype predisposes to exacerbations in young asthmatics taking regular salmeterol

B. Lipworth, S. Mukhopadhyay, SimonMing-Yuen Lee, 2006, Thorax.

Underuse of β-blockers in heart failure and chronic obstructive pulmonary disease

D. Price, B. Lipworth, V. Carter, 2016, Heart.

Sensitive Serum Thyrotropin Assay Assessed for Efficiency of Screening Hospital Patients

B. Lipworth, Cahlum G. Fraser, 2004 .

Tiotropium in asthma.

B. Lipworth, 2015, The Lancet. Respiratory medicine.