W. Hong

发表

Abstract PR-03: Genetic variations in microRNA biogenesis genes as predictors for risk of second primary tumor (SPT) and/or recurrence in patients with early‐stage head and neck cancer

Edward S. Kim, M. Spitz, S. Lippman, 2010 .

Higher potency of N-(4-hydroxyphenyl)retinamide than all-trans-retinoic acid in induction of apoptosis in non-small cell lung cancer cell lines.

W. Hong, J. Kurie, C. Zou, 1998, Clinical cancer research : an official journal of the American Association for Cancer Research.

Accumulation of p53 Protein and Retinoic Acid Receptorin Retinoid

S. Lippman, R. Lotan, W. Hong, 1997 .

Chemopreventive effects of deguelin, a novel Akt inhibitor, on tobacco-induced lung tumorigenesis.

R. Price, W. Hong, D. Cody, 2005, Journal of the National Cancer Institute.

Clinical significance of cyclin B1 protein expression in squamous cell carcinoma of the tongue.

W. Hong, A. El‐Naggar, J. Soria, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Overexpression of cyclin B1 in early-stage non-small cell lung cancer and its clinical implication.

F. Khuri, W. Hong, J. Soria, 2000, Cancer research.

Advances in Brief Overexpression of Cyclin B 1 in Early-Stage Non-Small Cell Lung Cancer and Its Clinical Implication 1

Diane D. Liu, F. Khuri, W. Hong, 2000 .

Effective treatment of early endobronchial cancer with regional administration of liposome-p53 complexes.

W. Hong, R. Perez-soler, G. Lozano, 1998, Journal of the National Cancer Institute.

Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing

Yu Cao, Yuanqing Ye, Harshad Mahadeshwar, 2014, Science.

Expression of hepatoma-derived growth factor is a strong prognostic predictor for patients with early-stage non-small-cell lung cancer.

F. Khuri, W. Hong, J. Lee, 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Overview of combined modality therapies for head and neck cancer.

W. Hong, I. Dimery, Isaiah W. Dimery, 1993, Journal of the National Cancer Institute.

Head and Neck Cancer

S. Lippman, W. Hong, R. Weichselbaum, 1993, Cancer treatment and research.

The BATTLE trial: personalizing therapy for lung cancer.

Edward S. Kim, S. Lippman, F. Khuri, 2011, Cancer discovery.

Comprar Holland-Frei Cancer Medicine 8th | Waun Ki Hong | 9781607950141 | Mcgraw-Hill Education

R. Bast, W. Hong, R. Weichselbaum, 2010 .

A risk model for prediction of lung cancer.

Matthew B Schabath, Sanjay Shete, Christopher I Amos, 2007, Journal of the National Cancer Institute.

Stress Pathway Activation Induces Phosphorylation of Retinoid X Receptor*

W. Hong, J. Woodgett, D. Mangelsdorf, 2000, The Journal of Biological Chemistry.

Genomic heterogeneity of multiple synchronous lung cancer

Dongmei Lin, Li Zhang, John V Heymach, 2016, Nature Communications.

In Support of a Patient-Driven Initiative and Petition to Lower the High Price of Cancer Drugs.

James Allison, Stephen Forman, Massimo Cristofanilli, 2015, Mayo Clinic proceedings.

Lung Cancer, Third Edition

W. Hong, J. Roth, J. Cox, 2008 .

An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

Michael Peyton, John D. Minna, Li Shen, 2012, Clinical Cancer Research.

Randomized trial of 13-cis retinoic acid compared with retinyl palmitate with or without beta-carotene in oral premalignancy.

Edward S. Kim, S. Lippman, F. Khuri, 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Abnormalities of the TITF-1 Lineage-Specific Oncogene in NSCLC: Implications in Lung Cancer Pathogenesis and Prognosis

Humam Kadara, Diane D. Liu, Diane D Liu, 2011, Clinical Cancer Research.

Comprehensive Biomarker Analysis and Final Efficacy Results of Sorafenib in the BATTLE Trial

Michael Peyton, John D. Minna, Lixia Diao, 2013, Clinical Cancer Research.

Interdigitating versus concurrent chemotherapy and radiotherapy for limited small cell lung cancer.

A. Garden, W. Hong, J. Roth, 1995, International journal of radiation oncology, biology, physics.

Implication of the Insulin-like Growth Factor-IR Pathway in the Resistance of Non–small Cell Lung Cancer Cells to Treatment with Gefitinib

Edward S. Kim, W. Hong, F. Ciardiello, 2007, Clinical Cancer Research.

A Five-Gene and Corresponding Protein Signature for Stage-I Lung Adenocarcinoma Prognosis

John D. Minna, Humam Kadara, Edward S. Kim, 2010, Clinical Cancer Research.

Epidermal Growth Factor Receptor Expression and Gene Copy Number in the Risk of Oral Cancer

Edward S. Kim, W. Hong, J. Lee, 2010, Cancer Prevention Research.

Influence of technologic advances on outcomes in patients with unresectable, locally advanced non-small-cell lung cancer receiving concomitant chemoradiotherapy.

Radhe Mohan, Edward S. Kim, Xiong Wei, 2010, International journal of radiation oncology, biology, physics.

Enolase-alpha is frequently down-regulated in non-small cell lung cancer and predicts aggressive biological behavior.

W. Hong, Y. Chang, L. Mao, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

General keynote: the impact of cancer chemoprevention.

W. Hong, 2003, Gynecologic oncology.

The Biology and Prevention of Aerodigestive Tract Cancers

W. Hong, G. Newell, W. Hong, 2012, Advances in Experimental Medicine and Biology.

Structural basis for depletion of heat shock protein 90 client proteins by deguelin.

W. Hong, Hyun-Ju Park, J. Myers, 2007, Journal of the National Cancer Institute.

Identifying and recruiting healthy control subjects from a managed care organization: a methodology for molecular epidemiological case-control studies of cancer.

M. Spitz, W. Hong, R. Chamberlain, 1997, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

13-cis-retinoic acid in the treatment of oral leukoplakia.

W. Hong, E. Atkinson, J. Batsakis, 1986, The New England journal of medicine.

Phase II Randomized, Placebo-Controlled Trial of Green Tea Extract in Patients with High-Risk Oral Premalignant Lesions

Diane D. Liu, W. Hong, I. Wistuba, 2009, Cancer Prevention Research.

Heterodimerization of insulin-like growth factor receptor/epidermal growth factor receptor and induction of survivin expression counteract the antitumor action of erlotinib.

Edward S. Kim, W. Hong, Ho-Yyoung Lee, 2006, Cancer research.

BESCT (Biology, Education, Screening, Chemoprevention and Treatment) Program

W. Hong, W. Hong, 2010 .

Evidence That Retinoic Acid Receptor β Induction by Retinoids Is Important for Tumor Cell Growth Inhibition*

R. Lotan, W. Hong, Shi-Yong Sun, 2000, The Journal of Biological Chemistry.

Augmentation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by the synthetic retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid (CD437) through up-regulation of TRAIL receptors in human lung cancer cells.

W. Hong, R. Lotan, S. Y. Sun, 2000, Cancer research.

Induction of Fas expression and augmentation of Fas/Fas ligand-mediated apoptosis by the synthetic retinoid CD437 in human lung cancer cells.

W. Hong, R. Lotan, S. Y. Sun, 2000, Cancer research.

The impact of current staging procedures in assessing disease extent of prostatic adenocarcinoma.

James B. Nickson, W. Hong, R. Finney, 1979, The Journal of urology.

The Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor ZD 1839 ( Iressa ) Suppresses cSrc and Pak 1 Pathways and Invasiveness of Human Cancer Cells

C. J. Barnes, R. Lotan, W. Hong, 2004 .

An A ttenuated A denovirus, O NYX-015, A s M outhwash T herapy for P remalignant O ral D ysplasia

C. Rudin, S. Lippman, W. Hong, 2006 .

An apple a day...does it really keep the doctor away? The current state of cancer chemoprevention.

Edward S. Kim, W. Hong, 2005, Journal of the National Cancer Institute.

Phase 2 bioadjuvant study of interferon alfa-2a, isotretinoin, and vitamin E in locally advanced squamous cell carcinoma of the head and neck: long-term follow-up.

Edward S. Kim, F. Khuri, W. Hong, 2005, Archives of otolaryngology--head & neck surgery.

Strategies in Lung Cancer Chemoprevention

Edward S. Kim, F. Khuri, W. Hong, 2005 .

Phase II trial of 13-cis-retinoic acid plus interferon-α in recurrent head and neck cancer

R. Weber, S. Lippman, W. Hong, 1993, Investigational new drugs.

Initial clinical trial of oral TAC-101, a novel retinoic acid receptor-alpha selective retinoid, in patients with advanced cancer.

W. Hong, J. Marshall, N. Rizvi, 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Cyclin D1 and p16 alterations in advanced premalignant lesions of the upper aerodigestive tract: role in response to chemoprevention and cancer development.

W. Hong, A. El‐Naggar, L. Mao, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Cyclin D 1 and p 16 Alterations in Advanced Premalignant Lesions of the Upper Aerodigestive Tract : Role in Response to Chemoprevention and Cancer Development 1

Diane D. Liu, W. Hong, A. El‐Naggar, 2001 .

The impact of smoking status, disease stage, and index tumor site on second primary tumor incidence and tumor recurrence in the head and neck retinoid chemoprevention trial.

Edward S. Kim, S. Lippman, F. Khuri, 2001, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

A randomized clinical trial of 4-hydroxyphenylretinamide for high-grade squamous intraepithelial lesions of the cervix.

S. Lippman, R. Lotan, W. Hong, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

A Randomized Clinical Trial of 4-Hydroxyphenylretinamide for High-Grade Squamous Intraepithelial Lesions of the Cervix 1

S. Lippman, R. Lotan, W. Hong, 2001 .

Biomolecular markers as intermediate end points in chemoprevention trials of upper aerodigestive tract cancer

W. Hong, V. Papadimitrakopoulou, W. Hong, 2000, International journal of cancer.

Differential responses of normal, premalignant, and malignant human bronchial epithelial cells to receptor-selective retinoids.

R. Lotan, W. Hong, J. Kurie, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

Chemoprevention in head and neck cancer: basic science and clinical application.

W. Hong, V. Papadimitrakopoulou, C. Geyer, 1998, Seminars in radiation oncology.

Survival after treatment of small-cell lung cancer: an endless uphill battle.

W. Hong, B. Glisson, W. Hong, 1997, Journal of the National Cancer Institute.

Retinoids in Head and Neck Chemoprevention

W. Hong, V. Papadimitrakopoulou, W. Hong, 1997, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Retinoid refractoriness occurs during lung carcinogenesis despite functional retinoid receptors.

R. Lotan, W. Hong, J. Nesbitt, 1995, Cancer research.

Potential of retinoids in cancer prevention.

S. Lippman, W. Hong, J. Kurie, 1994, Cancer treatment reviews.

Modulation by retinoic acid (RA) of squamous cell differentiation, cellular RA-binding proteins, and nuclear RA receptors in human head and neck squamous cell carcinoma cell lines.

P. Chambon, W. Hong, J. Clifford, 1994, Cancer research.

Randomized placebo-controlled trial of isotretinoin in chemoprevention of bronchial squamous metaplasia.

S. Lippman, J. Lee, W. Hong, 1994, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Differential expression of nuclear retinoid receptors in normal, premalignant, and malignant head and neck tissues.

R. Lotan, W. Hong, D. Shin, 1994, Cancer research.

Retinoid chemoprevention of aerodigestive carcinogenesis

S. Lippman, W. Hong, S. Benner, 1994 .

The natural history of cervical intraepithelial neoplasia: an argument for intermediate endpoint biomarkers.

W. Hong, W. Hittelman, R. Lotan, 1994, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Biomarkers in aerodigestive tract chemoprevention trials

S. Lippman, R. Lotan, W. Hong, 1993 .

The role of retinoids in preventing second lung cancers

S. Lippman, W. Hong, S. Benner, 1993 .

Adjuvant chemotherapy for resectable squamous cell carcinoma of the head and neck. Report on Intergroup Study 0034.

W. Hong, W. Hong, 1992, International journal of radiation oncology, biology, physics.

Determination of biomarkers for intermediate end points in chemoprevention trials.

S. Lippman, R. Lotan, W. Hong, 1992, Cancer research.

Anticlastogenic effects of 13-cis-retinoic acid in vitro.

W. Hong, J. Lee, T. Hsu, 1992, European journal of cancer.

Chemotherapy in head and neck cancer.

W. Hong, M. Kies, N. Levitan, 1983, The New England journal of medicine.

Chemoprevention of head and neck cancer. Potential use of retinoids.

W. Hong, W. Doos, 1985, Otolaryngologic clinics of North America.

Adjuvant chemotherapy of head and neck cancer: the past, the present, and the future.

W. Hong, I. Dimery, A. J. Choksi, 1988, Seminars in oncology.

Biomarkers as intermediate end points in chemoprevention trials.

R. Lotan, W. Hong, M. Wargovich, 1990, Journal of the National Cancer Institute.

Etoposide combined with cyclophosphamide plus vincristine compared with doxorubicin plus cyclophosphamide plus vincristine and with high-dose cyclophosphamide plus vincristine in the treatment of small-cell carcinoma of the lung: a randomized trial of the Bristol Lung Cancer Study Group.

W. Hong, J. Speer, J. Maroun, 1989, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Nuclear factor-kappaB (NF-kappaB) is frequently expressed in lung cancer and preneoplastic lesions.

Diane D. Liu, W. Hong, I. Wistuba, 2006, Cancer.

Head and Neck Cancer: A Multidisciplinary Approach

W. Hong, L. Harrison, R. Sessions, 2013 .

p53 protein accumulation and genomic instability in head and neck multistep tumorigenesis.

S. Lippman, W. Hong, J. Lee, 2001, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Multiple oral squamous epithelial lesions: are they genetically related?

W. Hong, S. Jang, L. Mao, 2001, Oncogene.

A prospective randomized trial of methotrexate versus cisplatin in the treatment of recurrent squamous cell carcinoma of the head and neck

S. Shapshay, W. Hong, B. Issell, 1983, Cancer.

Ifosfamide with Mesna Uroprotection in the Management of Lung Cancer

W. Hong, J. S. Lee, M. Raber, 1990, American journal of clinical oncology.

Safety and pharmacokinetic effects of TNP-470, an angiogenesis inhibitor, combined with paclitaxel in patients with solid tumors: evidence for activity in non-small-cell lung cancer.

F. Khuri, W. Hong, R. Herbst, 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

BATTLE-2 program: A biomarker-integrated targeted therapy study in previously treated patients with advanced non-small cell lung cancer (NSCLC).

K. Coombes, J. Lee, W. Hong, 2013 .

Changes in keratin expression during 7,12-dimethylbenz[a]anthracene-induced hamster cheek pouch carcinogenesis.

T. Slaga, W. Hong, D. Roop, 1990, Cancer research.

Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma

K. Ashizawa, Xin Hu, P. Scheet, 2019, Nature Communications.

Expression of epidermal growth factor receptor, polyamine levels, ornithine decarboxylase activity, micronuclei, and transglutaminase I in a 7,12-dimethylbenz(a)anthracene-induced hamster buccal pouch carcinogenesis model.

T. Slaga, R. Lotan, W. Hong, 1990, Cancer research.

Regression of oral leukoplakia with alpha-tocopherol: a community clinical oncology program chemoprevention study.

S. Lippman, W. Hong, R. Winn, 1993, Journal of the National Cancer Institute.

Polyamine measurements in the uterine cervix

R. Lotan, W. Hong, J. Lee, 1997, Journal of cellular biochemistry. Supplement.

Retinoic acid receptor beta and telomerase catalytic subunit expression in bronchial epithelium of heavy smokers.

Diane D. Liu, F. Khuri, R. Lotan, 2003, Journal of the National Cancer Institute.

Phase II Trials of Imatinib Mesylate and Docetaxel in Patients with Metastatic Non-small Cell Lung Cancer and Head and Neck Squamous Cell Carcinoma

W. Hong, I. Wistuba, J. Lee, 2011, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

A phase II study of STEALTH cisplatin (SPI-77) in patients with advanced non-small cell lung cancer.

F. Khuri, W. Hong, R. Herbst, 2001, Lung cancer.

Mediation of N-(4-hydoxyphenyl)retinamide-induced apoptosis in human cancer cells by different mechanisms.

S. Lippman, R. Lotan, W. Hong, 1999, Cancer research.

Vandetanib and indwelling pleural catheter for non-small-cell lung cancer with recurrent malignant pleural effusion.

Diane D. Liu, W. Hong, I. Wistuba, 2014, Clinical lung cancer.

Longitudinal study of smoking patterns in relation to the development of smoking‐related secondary primary tumors in patients with upper aerodigestive tract malignancies

M. Spitz, F. Khuri, W. Hong, 2004, Cancer.

Serum Levels of Insulin Growth Factor (IGF-I) and IGF-Binding Protein Predict Risk of Second Primary Tumors in Patients with Head and Neck Cancer

M. Spitz, W. Hong, Xifeng Wu, 2004, Clinical Cancer Research.

Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer.

S. Lippman, F. Khuri, R. Lotan, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Assessing environmental and occupational risk factors for lung cancer in Mexican–Americans

M. Spitz, W. Hong, Q. Dong, 2010, Cancer Causes & Control.

Induction chemotherapy in advanced squamous head and neck carcinoma with high‐dose cis‐platinum and bleomycin infusion

S. Shapshay, W. Hong, M. Strong, 1979, Cancer.

Biology of Human Tumors VEGF / VEGFR-2 Upregulates EZH 2 Expression in Lung Adenocarcinoma Cells and EZH 2 Depletion Enhances the Response to Platinum-Based and VEGFR-2 – Targeted Therapy

K. Coombes, Jing Wang, J. Minna, 2014 .

VEGF/VEGFR-2 Upregulates EZH2 Expression in Lung Adenocarcinoma Cells and EZH2 Depletion Enhances the Response to Platinum-Based and VEGFR-2–Targeted Therapy

K. Coombes, Jing Wang, J. Minna, 2014, Clinical Cancer Research.

The risk of second primary tumors after resection of stage I nonsmall cell lung cancer.

A. Sabichi, S. Lippman, W. Hong, 2003, The Annals of thoracic surgery.

Expression of cyclooxygenase‐1 and cyclooxygenase‐2 in bronchial epithelium and nonsmall cell lung carcinoma

W. Hong, J. Kurie, J. S. Lee, 2002, Cancer.

Frequent loss of imprinting at the IGF2 and H19 genes in head and neck squamous carcinoma

W. Hong, A. El‐Naggar, G. Clayman, 1999, Oncogene.

Value of p 16 INK 4 a and RASSF 1 A Promoter Hypermethylation in Prognosis of Patients with Resectable Non – Small Cell Lung Cancer

Diane D. Liu, W. Hong, J. Lee, 2004 .

Cyclin B1 overexpression and resistance to radiotherapy in head and neck squamous cell carcinoma.

Diane D. Liu, K. Ang, W. Hong, 2002, Cancer research.

Association of Ki-67, p53, and bcl-2 expression of the primary non-small-cell lung cancer lesion with brain metastatic lesion.

W. Hong, J. Roth, T. McDonnell, 2002, International journal of radiation oncology, biology, physics.

The synthetic retinoid CD437 selectively induces apoptosis in human lung cancer cells while sparing normal human lung epithelial cells.

R. Lotan, W. Hong, Shi-Yong Sun, 2002, Cancer research.

Identification of a novel synthetic triterpenoid, methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate, that potently induces caspase-mediated apoptosis in human lung cancer cells.

M. Sporn, R. Lotan, W. Hong, 2002, Molecular cancer therapeutics.

Phase I trial of cisplatin, pemetrexed, and imatinib mesylate in chemonaive patients with unresectable malignant pleural mesothelioma.

W. Hong, I. Wistuba, J. Lee, 2014, Clinical lung cancer.

Induction chemotherapy and cetuximab for locally advanced squamous cell carcinoma of the head and neck: results from a phase II prospective trial.

A. Garden, S. Lippman, W. Hong, 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Phase II study of tallysomycin S10b in patients with advanced head and neck cancer

W. Hong, M. Rozencweig, I. Krakoff, 1990, Investigational New Drugs.

Dietary intake of isothiocyanates: evidence of a joint effect with glutathione S-transferase polymorphisms in lung cancer risk.

M. Spitz, W. Hong, Xifeng Wu, 2000, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Oral Epithelium as a Surrogate Tissue for Assessing Smoking-Induced Molecular Alterations in the Lungs

Edward S. Kim, Diane D. Liu, W. Hong, 2008, Cancer Prevention Research.

Benzo(a)pyrene diol epoxide-induced chromosomal aberrations and risk of lung cancer.

M. Spitz, W. Hong, M. Bondy, 1996, Cancer research.

In vitro BPDE‐induced DNA adducts in peripheral lymphocytes as a risk factor for squamous cell carcinoma of the head and neck

M. Spitz, W. Hong, E. Sturgis, 2001, International journal of cancer.

Simultaneous Carcinomas of the Esophagus and Upper Aerodigestive Tract

S. Shapshay, M. Fried, W. Hong, 1980, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

Identification of Gene Signatures and Molecular Markers for Human Lung Cancer Prognosis using an In vitro Lung Carcinogenesis System

R. Lotan, W. Hong, I. Wistuba, 2009, Cancer Prevention Research.

Telomerase activity in head and neck squamous cell carcinoma and adjacent tissues.

S. Lippman, R. Lotan, W. Hong, 1996, Cancer research.

Implication of the Insulin-like Growth Factor-IRPathway in the Resistance of Non ^ small Cell Lung Cancer Cells toTreatment with

Edward S. Kim, W. Hong, F. Ciardiello, 2007 .

Serum Signature of Hypoxia-Regulated Factors Is Associated with Progression after Induction Therapy in Head and Neck Squamous Cell Cancer

K. Ang, S. Lippman, W. Hong, 2010, Molecular Cancer Therapeutics.

Advances in Brief Implication of Protein Kinase B / Akt and Bcl-2 / Bcl-XL Suppression by the Farnesyl Transferase Inhibitor SCH 66336 in Apoptosis Induction in Squamous Carcinoma Cells 1

F. Khuri, R. Lotan, W. Hong, 2003 .

Cells SCH 66336 in Apoptosis Induction in Squamous Carcinoma Suppression by the Farnesyl Transferase Inhibitor Implication of Protein Kinase B / Akt and Bcl-2 / Bcl-XL Updated

F. Khuri, R. Lotan, W. Hong, 2003 .

Implication of protein kinase B/Akt and Bcl-2/Bcl-XL suppression by the farnesyl transferase inhibitor SCH66336 in apoptosis induction in squamous carcinoma cells.

F. Khuri, R. Lotan, W. Hong, 2003, Cancer research.

Phase I study of farnesyl tranferase inhibitors (FTI) SCH66336 with paclitaxel in solid tumors: Dose finding, pharmacokinetics, efficacy/safety

P. Thall, F. Khuri, W. Hong, 2000 .

Survivin expression in normal human bronchial epithelial cells: an early and critical step in tumorigenesis induced by tobacco exposure.

W. Hong, L. Mao, Ho-Yyoung Lee, 2008, Carcinogenesis.

EGFR tyrosine kinase domain mutations are detected in histologically normal respiratory epithelium in lung cancer patients.

J. Minna, W. Hong, J. Roth, 2005, Cancer research.

Transcriptomic architecture of the adjacent airway field cancerization in non-small cell lung cancer.

K. Coombes, Jing Wang, W. Hong, 2014, Journal of the National Cancer Institute.

Phase I Study of the Farnesyltransferase Inhibitor Lonafarnib with Paclitaxel in Solid Tumors

Edward S. Kim, W. R. Bishop, P. Thall, 2004, Clinical Cancer Research.

Retinoic A cid R eceptor-Beta a s a P rognostic I ndicator i n Stage I N on-Small-Cell L ung C ancer

S. Lippman, F. Khuri, R. Lotan, 2000 .

Response of Non–Small Cell Lung Cancer Cells to the Inhibitors of Phosphatidylinositol 3-Kinase/Akt- and MAPK Kinase 4/c-Jun NH2-Terminal Kinase Pathways: An Effective Therapeutic Strategy for Lung Cancer

W. Hong, Y. Suh, Suyun Huang, 2005, Clinical Cancer Research.

Mechanisms of apoptosis induced by the synthetic retinoid CD437 in human non-small cell lung carcinoma cells

R. Lotan, W. Hong, Shi-Yong Sun, 1999, Oncogene.

Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcome.

John V Heymach, Kevin R Coombes, Lixia Diao, 2012, Journal of the National Cancer Institute.

CXCR2 expression in tumor cells is a poor prognostic factor and promotes invasion and metastasis in lung adenocarcinoma.

John V Heymach, Young-Ho Ahn, Roy S Herbst, 2013, Cancer research.

Clinical and Biomarker Outcomes of the Phase II Vandetanib Study from the BATTLE Trial

Edward S. Kim, S. Lippman, W. Hong, 2013, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Selective oral epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 is generally well-tolerated and has activity in non-small-cell lung cancer and other solid tumors: results of a phase I trial.

Roy S Herbst, W. Hong, J. Baselga, 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Gene therapy for non-small cell lung cancer: a preliminary report of a phase I trial of adenoviral p53 gene replacement.

W. Hong, J. Roth, S. Swisher, 1998, Seminars in oncology.

Telomere dysfunction: a potential cancer predisposition factor.

M. Spitz, W. Hong, Xifeng Wu, 2003, Journal of the National Cancer Institute.

Associations between cytochrome P4502E1 genotype, mutagen sensitivity, cigarette smoking and susceptibility to lung cancer.

M. Spitz, W. Hong, Xifeng Wu, 1997, Carcinogenesis.

Increased phospho-AKT (Ser(473)) expression in bronchial dysplasia: implications for lung cancer prevention studies.

S. Lam, W. Hong, T. McDonnell, 2003, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Increased Phospho-AKT (Ser473) Expression in Bronchial Dysplasia

S. Lam, W. Hong, T. McDonnell, 2003 .

Expression of DMBT1, a candidate tumor suppressor gene, is frequently lost in lung cancer.

J. Minna, A. Gazdar, W. Hong, 1999, Cancer research.

Treatment and prevention of intraepithelial neoplasia: an important target for accelerated new agent development.

M. Sporn, D. Alberts, S. Lam, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Clinical Prevention of Recurrence of Colorectal Adenomas by the Combination of Difluoromethylornithine and Sulindac: An Important Milestone

M. Sporn, W. Hong, W. Hong, 2008, Cancer Prevention Research.

9-cis-Retinoic Acid Treatment Increases Serum Concentrations of α-Tocopherol in Former Smokers

Diane D. Liu, R. Lotan, W. Hong, 2005, Clinical Cancer Research.

Effects of 9-cis-retinoic acid on the insulin-like growth factor axis in former smokers.

Diane D. Liu, M. Spitz, R. Lotan, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Head and Neck Cancer in Minority Populations

W. Hong, I. Dimery, R. Byers, 1989 .

Dietary folate intake and lung cancer risk in former smokers: a case-control analysis.

Hongbing Shen, M. Spitz, W. Hong, 2003, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Deguelin-Induced Inhibition of Cyclooxygenase-2 Expression in Human Bronchial Epithelial Cells

W. Hong, J. Pezzuto, J. Kurie, 2004, Clinical Cancer Research.

An Expanded Risk Prediction Model for Lung Cancer

M. Spitz, W. Hong, Xifeng Wu, 2008, Cancer Prevention Research.

Suppression of retinoic acid receptor beta in non-small-cell lung cancer in vivo: implications for lung cancer development.

R. Lotan, W. Hong, J. Lee, 1997, Journal of the National Cancer Institute.

A parallel study of in vitro sensitivity to benzo[a]pyrene diol epoxide and bleomycin in lung carcinoma cases and controls

M. Spitz, W. Hong, Xifeng Wu, 1998, Cancer.

HER Family Receptor Abnormalities in Lung Cancer Brain Metastases and Corresponding Primary Tumors

Carmen Behrens, Ignacio I Wistuba, K. Aldape, 2009, Clinical Cancer Research.

Hypermethylation of the death-associated protein kinase promoter attenuates the sensitivity to TRAIL-induced apoptosis in human non-small cell lung cancer cells.

Li Mao, Weiguo Wu, Ignacio I Wistuba, 2004, Molecular cancer research : MCR.

The use of improved and complete enrichment co-amplification at lower denaturation temperature (ICE COLD-PCR) method for the detection of EGFR and KRAS mutations from cell-free plasma DNA of non-small cell lung cancer (NSCLC) patients.

Edward S. Kim, W. Hong, I. Wistuba, 2014 .

Loss of PTEN expression as a prognostic marker for tongue cancer.

W. Hong, A. El‐Naggar, J. Soria, 2001, Archives of otolaryngology--head & neck surgery.

Joint effect of insulin-like growth factors and mutagen sensitivity in lung cancer risk.

M. Spitz, W. Hong, Xifeng Wu, 2000, Journal of the National Cancer Institute.

Benzo[a]pyrene diol epoxide-induced 3p21.3 aberrations and genetic predisposition to lung cancer.

M. Spitz, J. Minna, W. Hong, 1998, Cancer research.

Phase II study of a multidisciplinary approach with induction chemotherapy, followed by surgical resection, radiation therapy, and consolidation chemotherapy for unresectable malignant thymomas: final report.

Edward S. Kim, F. Khuri, W. Hong, 2004, Lung cancer.

Immunologic determinants of head and neck cancer response to induction chemotherapy.

W. Hong, R. Rossen, H. Savage, 1989, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Joint effect of insulin-like growth factors and mutagen sensitivity in lung cancer risk.

M. Spitz, W. Hong, C. Amos, 2000, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Laryngeal preservation by induction chemotherapy plus radiotherapy in locally advanced head and neck cancer: The M. D. Anderson cancer center experience

A. Garden, R. Weber, S. Lippman, 1994, Head & neck.

The role of induction chemotherapy for organ preservation in laryngeal carcinoma.

W. Hong, I. Dimery, R. Byers, 1990, Cancer treatment and research.

Podoplanin: a novel marker for oral cancer risk in patients with oral premalignancy.

Edward S. Kim, S. Lippman, W. Hong, 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Expression of retinoic acid receptor beta is associated with inhibition of keratinization in human head and neck squamous carcinoma cells.

W. Hong, C. Zou, R. Lotan, 1999, Differentiation; research in biological diversity.

All-trans-retinoic acid increases transforming growth factor-beta2 and insulin-like growth factor binding protein-3 expression through a retinoic acid receptor-alpha-dependent signaling pathway.

W. Hong, J. Kurie, P. Cohen, 1997, The Journal of biological chemistry.

Novel Susceptibility Loci for Second Primary Tumors/Recurrence in Head and Neck Cancer Patients: Large-Scale Evaluation of Genetic Variants

Jian Gu, J Jack Lee, Yuanqing Ye, 2009, Cancer Prevention Research.

Genetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma.

Edward S. Kim, S. Lippman, Hushan Yang, 2010, Carcinogenesis.

Mutagen sensitivity as a predictor of tumor recurrence in patients with cancer of the upper aerodigestive tract.

M. Spitz, S. Lippman, F. Khuri, 1998, Journal of the National Cancer Institute.

Expression of DMBT 1 , a Candidate Tumor Suppressor Gene , Is Frequently Lost in Lung Cancer 1

J. Minna, W. Hong, A. Gazdar, 1999 .

Randomized phase III trial of low-dose isotretinoin for prevention of second primary tumors in stage I and II head and neck cancer patients.

Edward S. Kim, S. Lippman, F. Khuri, 2006, Journal of the National Cancer Institute.

Rapid induction of apoptosis in human C33A cervical carcinoma cells by the synthetic retinoid 6‐[3‐(1‐adamantyl)hydroxyphenyl]‐2‐naphtalene carboxylic acid (CD437)

R. Lotan, W. Hong, R. Lotan, 1997, International journal of cancer.

Pharmacology, Clinical Efficacy and Adverse Effects of Vindesine Sulfate, A New Vinca Alkaloid

R. J. Cersosimo, W. Hong, R. Bromer, 1983, Pharmacotherapy.

All-trans Retinoic Acid Converts E 2 F into a Transcriptional Suppressor and Inhibits the Growth of Normal Human Bronchial Epithelial Cells Through a Retinoic Acid Receptor – dependent Signaling Pathway

W. Hong, M. Andreeff, J. Kurie, 1998 .

Involvement of reactive oxygen species in N-(4-hydroxyphenyl)retinamide-induced apoptosis in cervical carcinoma cells.

R. Lotan, W. Hong, R. Lotan, 1997, Journal of the National Cancer Institute.

13-cis-Retinoic Acid and Interferon α -2a: Effective Combination. Therapy for Advanced Squamous Cell Carcinoma of the Skin

R. Weber, S. Lippman, W. Hong, 1992 .

Abstract LB-88: Gene expression signatures predictive of clinical outcome and tumor mutations in refractory NSCLC patients (pts) in the BATTLE trial (Biomarker-integrated Approaches of Targeted Therapy for Lung Cancer Elimination)

Edward S. Kim, J. Weinstein, K. Coombes, 2011 .

977 Phase I/II trial evaluating blockade of tumour blood supply and tumour cell proliferation with combined bevacizumab and erlotinib HCl as targeted cancer therapy in patients with recurrent non-small cell lung cancer

Edward S. Kim, W. Hong, R. Herbst, 2003 .

Cancer chemoprevention in the 21st century: genetics, risk modeling, and molecular targets.

M. Spitz, S. Lippman, W. Hong, 2000, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Chromosome instability in lymphocytes: a potential indicator of predisposition to oral premalignant lesions.

M. Spitz, S. Lippman, W. Hong, 2002, Cancer research.

Activation of p53 gene expression in premalignant lesions during head and neck tumorigenesis.

W. Hong, J. Roth, W. Hittelman, 1994, Cancer research.

The use of cis-retinoic acid in recurrent respiratory papillomatosis of the larynx: a randomized pilot study.

W. Hong, L. Itri, M. Strong, 1988, American journal of otolaryngology.

Differential effects of retinoic acid on the in vitro growth and cell‐surface glycoconjugates of 2 human head and neck squamous‐cell carcinomas

R. Lotan, W. Hong, D. Lotan, 1987, International journal of cancer.

Identification of retinamides that are more potent than N-(4-hydroxyphenyl)retinamide in inhibiting growth and inducing apoptosis of human head and neck and lung cancer cells.

V. Steele, S. Lippman, R. Lotan, 2001, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Results of a phase II double-blinded randomized clinical trial of difluoromethylornithine for cervical intraepithelial neoplasia grades 2 to 3.

W. Hong, A. Malpica, M. Follen, 2005, Clinical cancer research : an official journal of the American Association for Cancer Research.

Phase I dose de-escalation trial of alpha-difluoromethylornithine in patients with grade 3 cervical intraepithelial neoplasia.

R. Lotan, W. Hong, J. Lee, 1998, Clinical cancer research : an official journal of the American Association for Cancer Research.

Hypermethylation of the Retinoic Acid Receptor-β2 Gene in Head and Neck Carcinogenesis

S. Lippman, R. Lotan, W. Hong, 2004, Clinical Cancer Research.

Treatment of patients with recurrent or metastatic squamous cell carcinoma of the head and neck: current status and future directions.

S. Lippman, F. Khuri, W. Hong, 2000, Seminars in oncology.

Induction of apoptosis by retinoids in human cervical-carcinoma cell-lines.

W. Hong, D. Lotan, R. Lotan, 1995, International journal of oncology.

Mutagen sensitivity as a risk factor for second malignant tumors following malignancies of the upper aerodigestive tract.

M. Spitz, W. Hong, C. Amos, 1994, Journal of the National Cancer Institute.

Inhibition of growth and squamous-cell differentiation markers in cultured human head and neck squamous carcinoma cells by beta-all-trans retinoic acid.

R. Lotan, W. Hong, D. Lotan, 1990, International journal of cancer.

Treatment of patients with small-cell lung cancer refractory to etoposide and cisplatin with the topoisomerase I poison topotecan.

W. Hong, R. Perez-soler, F. Fossella, 1996, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Evidence of a retinoid signaling alteration involving the activator protein 1 complex in tumorigenic human bronchial epithelial cells and non-small cell lung cancer cells.

W. Hong, J. Kurie, M. Dawson, 1997, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Retinoids in Head and Neck Chemoprevention (44179)

W. Hong, V. Papadimitrakopoulou, W. Hong, 1997 .

Larynx Preservation Using Induction Chemotherapy plus Radiation Therapy as an Alternative to Laryngectomy in Advanced Head and Neck Cancer A Long‐Term Follow‐up Report

W. Hong, S. Zeitels, P. Calarese, 1991, American Journal of Clinical Oncology.

Sequential increases in proliferating cell nuclear antigen expression in head and neck tumorigenesis: a potential biomarker.

W. Hong, W. Hittelman, D. Shin, 1993, Journal of the National Cancer Institute.

Suppression by retinoic acid of epidermal growth factor receptor autophosphorylation and glycosylation in cultured human head and neck squamous carcinoma cells.

R. Lotan, W. Hong, P. Steck, 1992, Journal of the National Cancer Institute. Monographs.

Induction chemotherapy followed by radiotherapy versus radiotherapy alone in patients with advanced nasopharyngeal carcinoma : Results of a matched cohort study

A. Garden, K. Ang, S. Lippman, 1997 .

Role of paclitaxel, ifosfamide, and cisplatin in patients with recurrent or metastatic squamous cell carcinoma of the head and neck.

S. Lippman, F. Khuri, W. Hong, 1998, Seminars in oncology.

Abstract 4686: T cell repertoire evolution from the normal lung to invasive lung adenocarcinoma

P. Scheet, W. Hong, I. Wistuba, 2018, Immunology.

P2.02-013 Investigation of Genomic and TCR Repertoire Evolution of AAH, AIS, MIA to Invasive Lung Adenocarcinoma by Multiregion Exome and TCR Sequencing

J. Fujimoto, Xin Hu, W. Hong, 2017 .

Laryngeal preservation for advanced laryngeal and hypopharyngeal cancers.

A. Garden, R. Weber, W. Hong, 1995, Archives of otolaryngology--head & neck surgery.

Posttranslational mechanisms contribute to the suppression of specific cyclin:CDK complexes by all-trans retinoic acid in human bronchial epithelial cells.

W. Hong, J. Kurie, G. Walsh, 1999, Cancer research.

Anti-retinoic acid (RA) antibody binding to human premalignant oral lesions, which occurs less frequently than binding to normal tissue, increases after 13-cis-RA treatment in vivo and is related to RA receptor beta expression.

S. Lippman, R. Lotan, W. Hong, 1995, Cancer research.

Cellular and humoral immune responses to adenovirus and p53 protein antigens in patients following intratumoral injection of an adenovirus vector expressing wild-type p53 (Ad-p53)

F. Khuri, W. Hong, J. Roth, 2000, Cancer Gene Therapy.

C-CAM1, a candidate tumor suppressor gene, is abnormally expressed in primary lung cancers.

W. Hong, L. Mao, S. H. Lin, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

Correlates of mutagen sensitivity in patients with upper aerodigestive tract cancer.

M. Spitz, S. Lippman, F. Khuri, 1997, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

The Synthetic Heteroarotinoid SHetA 2 Induces Apoptosis in Squamous Carcinoma Cells through a Receptor-independent and Mitochondria-dependent Pathway 1

R. Lotan, W. Hong, K. Berlin, 2003 .

Detection of Nuclear Retinoic Acid Receptor mRNA in Histological Tissue Sections Using Nonradioactive In Situ Hybridization Histochemistry

R. Lotan, W. Hong, J. Clifford, 1994, Diagnostic molecular pathology : the American journal of surgical pathology, part B.

changes in a mouse model of oral tumorigenesis may help refine prevention and treatment strategies in patients with oral cancer.

S. Lippman, W. Hong, J. Lachuer, 2016 .

13-cis-Retinoic Acid Plus Interferon α -2a: Highly Active Systemic Theraphy for Squamous Cell Carcinoma of the Cervix

S. Lippman, W. Hong, J. Kavanagh, 1992 .

Advances in Brief Benzo [ fl ] pyrene Diol Epoxide-induced 3 p 21 . 3 Aberrations and Genetic Predisposition to Lung Cancer 1

Xifeng, J. Minna, W. Hong, 2006 .

Reduced expression levels of nucleotide excision repair genes in lung cancer: a case-control analysis.

M. Spitz, W. Hong, Q. Wei, 2000, Carcinogenesis.

Sorafenib treatment efficacy and KRAS biomarker status in the Biomarker-Integrated Approaches of Targeted Therapy for Lung Cancer Elimination (BATTLE) trial.

W. Hong, I. Wistuba, R. Herbst, 2010 .

The evolution of mature teratoma from malignant testicular tumors

R. Wittes, W. Hong, W. Whitmore, 1977, Cancer.

Genome-wide association study of genetic predictors of overall survival for non-small cell lung cancer in never smokers.

Joe Y. Chang, V Shane Pankratz, Yuanqing Ye, 2013, Cancer research.

Overexpressed Activated Retinoid X Receptors Can Mediate Growth Inhibitory Effects of Retinoids in Human Carcinoma Cells*

R. Lotan, W. Hong, M. Dawson, 1998, The Journal of Biological Chemistry.

Implication of p53 in growth arrest and apoptosis induced by the synthetic retinoid CD437 in human lung cancer cells.

R. Lotan, W. Hong, Shi-Yong Sun, 1999, Cancer research.

the Synthetic Retinoid CD 437 in Human Lung Cancer Cells Implication of p 53 in Growth Arrest and Apoptosis Induced by Updated

R. Lotan, W. Hong, Shi-Yong Sun, 1999 .

Implication of p 53 in Growth Arrest and Apoptosis Induced by the Synthetic Retinoid CD 437 in Human Lung Cancer Cells 1

R. Lotan, W. Hong, Shi-Yong Sun, 1999 .

Phenotypic diversity of the lung vasculature in experimental models of metastases.

W. Hong, Imran T. Mohiuddin, W. Arap, 2005, Chest.

The KRAS-variant and treatment response in BATTLE-1.

Edward S. Kim, F. Slack, Jun Yu, 2014 .

Antisense oligonucleotides directed at the bcl-xl gene product augment chemotherapy response in mesothelioma.

W. Hong, Xiaobo X. Cao, Steven D. Miller, 2004, Molecular cancer therapeutics.

Activation of melanoma antigen tumor antigens occurs early in lung carcinogenesis.

W. Hong, R. Morice, J. Soria, 2001, Cancer research.

Effectiveness of combined induction chemotherapy and radiotherapy in advanced nasopharyngeal carcinoma.

R. Weber, W. Hong, L. Peters, 1993, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Phase II trial of carboplatin plus cisplatin in recurrent and advanced squamous cell carcinoma of the head and neck.

W. Hong, R. Winn, I. Dimery, 1991, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Phase II trial of trimetrexate for unresectable or metastatic non-small cell bronchogenic carcinoma

W. Hong, R. Winn, F. Fossella, 1992, Investigational New Drugs.

Cis-diamminedichlorplatinum-induced acute renal failure in the rat.

J. Kaufman, W. Hong, B. Trump, 1982, Kidney international.

Alterations of PTEN/MMAC1, a candidate tumor suppressor gene, and its homologue, PTH2, in small cell lung cancer cell lines

W. Hong, L. Mao, L. Su, 1998, Oncogene.

NCCN Practice Guidelines for Head and Neck Cancers.

R H Wheeler, J. Shah, W. Hong, 2000, Oncology.

Identification of three distinct tumor suppressor loci on the short arm of chromosome 9 in small cell lung cancer.

J. Minna, W. Hong, L. Mao, 1997, Cancer research.

A Multidisciplinary Approach to Therapy for Unresectable Malignant Thymoma

W. Hong, J. Roth, J. Nesbitt, 1998, Annals of Internal Medicine.

Improved therapeutic index by leucovorin of edatrexate, cyclophosphamide, and cisplatin regimen for non-small-cell lung cancer.

S. Lippman, W. Hong, H. Libshitz, 1992, Journal of the National Cancer Institute.

Vindesine versus Vindesine with Cis-Platinum in Metastatic Non-Small Cell Lung Cancer

W. Hong, G. Snider, R. Pugatch, 1981 .

Phase I/II study of cisplatin, 5-fluorouracil and α-interferon for recurrent carcinoma of the head and neck

S. Lippman, W. Hong, I. Dimery, 2004, Investigational New Drugs.

A phase II study of ifosfamide in recurrent squamous cell carcinoma of the head and neck.

S. Lippman, W. Hong, I. Dimery, 1996, American journal of clinical oncology.

Phase II study of carboplatin and continuous infusion bleomycin followed by cisplatin and 5-fluorouracil in recurrent head and neck cancer.

S. Lippman, W. Hong, R. Winn, 1995, Annals of oncology : official journal of the European Society for Medical Oncology.

p 53 Protein Accumulation and Genomic Instability in Head and Neck Multistep Tumorigenesis 1

S. Lippman, W. Hong, J. Lee, 2001 .

The Synthetic Retinoid CD 437 Selectively Induces Apoptosis in Human Lung Cancer Cells while Sparing Normal Human Lung Epithelial Cells 1

R. Lotan, W. Hong, Shi-Yong Sun, 2002 .

Frequent inactivation of p16INK4a in oral premalignant lesions

S. Lippman, R. Lotan, W. Hong, 1997, Oncogene.

Transformation of lymphoma to amyloidoma following radiation therapy.

W. Hong, A. Rubinow, N. Levitan, 1985, Human pathology.

Reduction to homozygosity at the SIS/PDGF-2 locus in human mesenchymal tumors.

W. Hong, R. Ferrell, D. Shin, 1988, Biochemical and biophysical research communications.

Adenovirus-mediated p53 gene transfer in advanced non-small-cell lung cancer.

F. Khuri, W. Hong, J. Roth, 1999, Journal of the National Cancer Institute.

Induction chemotherapy for organ preservation in advanced laryngeal cancer: Is there a role?

W. Hong, G. Wolf, G. Wolf, 1995, Head & neck.

Gemcitabine (G) with concurrent chest radiation (XRT) followed by consolidation chemotherapy with gemcitabine plus cisplatin (CDDP): A phase I trial for patients with stage III non-small cell lung cancer (NSCLC)

F. Khuri, W. Hong, R. Herbst, 2000 .

The incidence of hypercalcemia in squamous cell carcinoma of the head and neck.

W. Hong, E. Dorman, M. Strong, 1984, Head & neck surgery.

Cis-diamminedichiorplatinum-induced acute renal failure in the rat

W. Hong, B. Trump, J. Kaufman, 1982 .

Editorial. Induction chemotherapy for advanced head and neck cancer

W. Hong, 1988 .

Chemotherapy of head and neck cancer.

W. Hong, M. Kies, N. Levitan, 1985 .

Implication of c-Myc in apoptosis induced by the retinoid CD437 in human lung carcinoma cells

R. Lotan, W. Hong, Shi-Yong Sun, 1999, Oncogene.

Early genetic changes during upper aerodigestive tract tumorigenesis

W. Hong, W. Hittelman, D. Shin, 1993, Journal of cellular biochemistry. Supplement.

Abstract 5166: Sex determining region Y-box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung

Edward S. Kim, J. Minna, W. Hong, 2010 .

Insulin-like growth factor binding protein-3 inhibits the growth of non-small cell lung cancer.

Pinchas Cohen, W. Hong, J. Kurie, 2002, Cancer research.

A pilot clinical laboratory trial of paclitaxel and endobronchial brachytherapy in patients with non-small cell lung cancer.

W. Hong, R. Komaki, W. Hittelman, 1999, Seminars in radiation oncology.

Squamous cell carcinoma of the upper aerodigestive tract. A case comparison analysis

M. Spitz, W. Hong, H. Goepfert, 1988, Cancer.

Hypermethylation of the Death-Associated Protein Kinase Promoter Attenuates the Sensitivity to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Induced Apoptosis in Human Non–Small Cell Lung Cancer Cells

W. Hong, I. Wistuba, Shi-Yong Sun, 2004, Molecular Cancer Research.

Prognostic implications of tumoral expression of insulin like growth factors 1 and 2 in patients with non-small-cell lung cancer.

Edward S. Kim, Diane D. Liu, S. Lippman, 2014, Clinical lung cancer.

Phase II study of paclitaxel, ifosfamide, and carboplatin in patients with recurrent or metastatic head and neck squamous cell carcinoma

S. Lippman, F. Khuri, W. Hong, 2001, Cancer.

Prospective randomized trial of high-dose cisplatin and fluorouracil infusion with or without sodium diethyldithiocarbamate in recurrent and/or metastatic squamous cell carcinoma of the head and neck.

W. Hong, R. Newman, I. Dimery, 1988, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Phase II study of combination weekly gemcitabine and vinorelbine in patients with untreated or previously treated non-small cell lung cancer

Diane D. Liu, F. Khuri, W. Hong, 2000 .

Reduced DNA repair capacity in lung cancer patients.

M. Spitz, W. Hong, Q. Wei, 1996, Cancer research.

In vitro protective effects of chemopreventive agents against bleomycin-induced genotoxicity in lymphoblastoid cell lines and peripheral blood lymphocytes of head and neck cancer patients.

M. Spitz, W. Hong, J. Lee, 1993, Cancer detection and prevention.

Concordance of oral HPV prevalence between patients with oropharyngeal cancer and their partners

W. Hong, J. Lee, M. Guo, 2016, Infectious Agents and Cancer.

Cancer Prevention by Delay

S. Lippman, W. Hong, W. Hong, 2002 .

Molecular and cellular biomarkers for field cancerization and multistep process in head and neck tumorigenesis

W. Hong, D. Shin, V. Papadimitrakopoulou, 1996, Cancer and Metastasis Reviews.

Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities.

Michael Peyton, Humam Kadara, Murim Choi, 2015, Cancer discovery.

Implication of mitochondria-derived reactive oxygen species, cytochrome C and caspase-3 in N-(4-Hydroxyphenyl)retinamide-induced apoptosis in cervical carcinoma cells

R. Lotan, W. Hong, N. Oridate, 1999, Oncogene.

Polyamine metabolism in carcinoma of the oral cavity compared with adjacent and normal oral mucosa.

W. Hong, D. Ota, K. Nishioka, 1987, American journal of surgery.

Recent advances in chemoprevention of cancer.

M. Sporn, W. Hong, M B Sporn, 1997, Science.

Phase I/II trial evaluating the anti-vascular endothelial growth factor monoclonal antibody bevacizumab in combination with the HER-1/epidermal growth factor receptor tyrosine kinase inhibitor erlotinib for patients with recurrent non-small-cell lung cancer.

Edward S. Kim, Diane D. Liu, W. Hong, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

From Protocols to Publications: A Study in Selective Reporting of Outcomes in Randomized Trials in Oncology.

D. Berry, L. Ellis, W. Hong, 2015, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Thymidylate Synthase 5′- and 3′-Untranslated Region Polymorphisms Associated with Risk and Progression of Squamous Cell Carcinoma of the Head and Neck

M. Spitz, W. Hong, Q. Wei, 2004, Clinical Cancer Research.

Phase II clinical trial of didemnin B in previously treated small cell lung cancer

W. Hong, R. Winn, R. Perez-soler, 2004, Investigational New Drugs.

Increased polysomies of chromosomes 7 and 17 during head and neck multistage tumorigenesis.

W. Hong, W. Hittelman, D. Shin, 1993, Cancer research.

Regional metastases in patients with advanced laryngeal cancer. Department of Veterans Affairs Laryngeal Cancer Study Group.

W. Hong, G. Wolf, S. Fisher, 1996, Archives of otolaryngology--head & neck surgery.

A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer

I. Tannock, F. Khuri, W. Hong, 2000, Nature Medicine.

Frequent microsatellite alterations at chromosomes 9p21 and 3p14 in oral premalignant lesions and their value in cancer risk assessment

S. Lippman, W. Hong, L. Mao, 1996, Nature Medicine.

Estrogen receptors in normal salivary gland and salivary gland carcinoma.

W. Hong, I. Dimery, H. Goepfert, 1987, Archives of otolaryngology--head & neck surgery.

Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer.

W. Hong, G. Laramore, W. Henderson, 1991, The New England journal of medicine.

p53 Expression: Predicting Recurrence and Second Primary Tumors in Head and Neck Squamous Cell Carcinoma

S. Lippman, W. Hong, J. Lee, 1996 .

Phase II and biologic study of interferon alfa, retinoic acid, and cisplatin in advanced squamous skin cancer.

Diane D. Liu, S. Lippman, F. Khuri, 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

P h a s e I I a n d B i o logic S tudy o f I nterferon A lfa, R etinoic Acid, a nd C isplatin i n A dvanced S quamous S kin C ancer

Diane D. Liu, S. Lippman, F. Khuri, 2002 .

Sequential germ cell tumor without prior involvement of the testes.

W. Hong, R. Pugatch, W. Doos, 1981, The Journal of urology.

Evaluation of glutathione S‐transferase polymorphisms and mutagen sensitivity as risk factors for the development of second primary tumors in patients previously diagnosed with early‐stage head and neck cancer

M. Spitz, W. Hong, Xifeng Wu, 2006, Cancer.

Testis tumor markers: how accurate are they?

W. Hong, C. Olsson, R. deVere White, 1981, The Journal of urology.

Rapidly Expanding Retroperitoneal Mass

W. Hong, C. Olsson, S. Gerzof, 1980 .

Differential induction of apoptosis by all-trans-retinoic acid and N-(4-hydroxyphenyl)retinamide in human head and neck squamous cell carcinoma cell lines.

R. Lotan, W. Hong, D. Lotan, 1996, Clinical cancer research : an official journal of the American Association for Cancer Research.

Inhibition of growth and squamous‐cell differentiation markers in cultured human head and neck squamous carcinoma cells by β‐all‐trans retinoic acid

R. Lotan, W. Hong, D. Lotan, 1990 .

TSG101 is not mutated in lung cancer but a shortened transcript is frequently expressed in small cell lung cancer

J. Minna, W. Hong, L. Mao, 1998, Oncogene.

Induction of TIG3, a putative class II tumor suppressor gene, by retinoic acid in head and neck and lung carcinoma cells and its association with suppression of the transformed phenotype

R. Lotan, W. Hong, R. Chandraratna, 2003, Oncogene.

Combined interferon-alfa, 13-cis-retinoic acid, and alpha-tocopherol in locally advanced head and neck squamous cell carcinoma: novel bioadjuvant phase II trial.

Dan Liu, A. Garden, K. Ang, 2001, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Chemoprevention of lung cancer.

Edward S. Kim, W. Hong, S. Lantuejoul, 2003, The Lancet. Oncology.

Proteomics-based identification of proteins secreted in apical surface fluid of squamous metaplastic human tracheobronchial epithelial cells cultured by three-dimensional organotypic air-liquid interface method.

R. Lotan, W. Hong, I. Wistuba, 2007, Cancer research.

Three-Dimensional Organotypic Air-Liquid Interface Method Tracheobronchial Epithelial Cells Cultured by Apical Surface Fluid of Squamous Metaplastic Human Proteomics-Based Identification of Proteins Secreted in

R. Lotan, W. Hong, I. Wistuba, 2007 .

Identification of receptor-selective retinoids that are potent inhibitors of the growth of human head and neck squamous cell carcinoma cells.

R. Lotan, W. Hong, Shi-Yong Sun, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

Overexpression of retinoic acid receptor beta in head and neck squamous cell carcinoma cells increases their sensitivity to retinoid-induced suppression of squamous differentiation by retinoids.

W. Hong, D. Lotan, R. Lotan, 1999, Cancer research.

Accumulation of p53 protein and retinoic acid receptor beta in retinoid chemoprevention.

S. Lippman, R. Lotan, W. Hong, 1997, Clinical cancer research : an official journal of the American Association for Cancer Research.

Increased Retinoic Acid Responsiveness in Lung Carcinoma Cells that Are Nonresponsive Despite the Presence of Endogenous Retinoic Acid Receptor (RAR) β by Expression of Exogenous Retinoid Receptors Retinoid X Receptor α, RARα, and RARγ

Reuben Lotan, R. Lotan, W. Hong, 2001 .

Localization of insulin-like growth factor binding protein-2 messenger RNA during postnatal brain development: correlation with insulin-like growth factors

W. Hong, J. Roth, J. Kurie, 1993 .

All-trans-Retinoic Acid Inhibits Jun N-Terminal Kinase by Increasing Dual-Specificity Phosphatase Activity

W. Hong, D. Mangelsdorf, J. Kurie, 1999, Molecular and Cellular Biology.

Prognostic implication of microsatellite alteration profiles in early-stage non-small cell lung cancer.

F. Khuri, W. Hong, J. Lee, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

Randomized phase III intergroup trial of isotretinoin to prevent second primary tumors in stage I non-small-cell lung cancer.

S. Lippman, F. Khuri, R. Lotan, 2001, Journal of the National Cancer Institute.

N-(4-hydroxyphenyl)retinamide in the chemoprevention of squamous metaplasia and dysplasia of the bronchial epithelium.

S. Lippman, F. Khuri, R. Lotan, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

Differential effects of synthetic nuclear retinoid receptor-selective retinoids on the growth of human non-small cell lung carcinoma cells.

R. Lotan, W. Hong, Shi-Yong Sun, 1997, Cancer research.

Chemoprevention of Upper Aerodigestive Tract Cancer

Edward S. Kim, F. Khuri, W. Hong, 2005 .

Biologic correlates of a biochemoprevention trial in advanced upper aerodigestive tract premalignant lesions.

Diane D. Liu, W. Hong, J. Lee, 2002, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Treatment and Prevention of Intraepithelial Neoplasia: An Important Target for Accelerated New Agent Development: Recommendations of the American Association for Cancer Research Task Force on the Treatment and Prevention of Intraepithelial Neoplasia

M. Sporn, D. Alberts, S. Lam, 2002 .

Treatment and Prevention of Intraepithelial Neoplasia : An Important Target for Accelerated New Agent Development Recommendations of the American Association for Cancer Research Task Force on the Treatment and Prevention of Intraepithelial Neoplasia 1

M. Sporn, D. Alberts, S. Lam, 2002 .

Suppression of retinoic acid receptor-beta in premalignant oral lesions and its up-regulation by isotretinoin.

J S Lee, S. Lippman, R. Lotan, 1995, The New England journal of medicine.

Value of p16INK4a and RASSF1A Promoter Hypermethylation in Prognosis of Patients with Resectable Non–Small Cell Lung Cancer

Diane D. Liu, W. Hong, J. Lee, 2004, Clinical Cancer Research.

Phase II study of TAS-106 in patients with platinum-failure recurrent or metastatic head and neck cancer and nasopharyngeal cancer

W. Hong, A. Tsao, E. Hui, 2013, Cancer medicine.

Phase II study of a liposome-entrapped cisplatin analog (L-NDDP) administered intrapleurally and pathologic response rates in patients with malignant pleural mesothelioma.

W. Hong, S. Swisher, R. Perez-soler, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Phase I clinical and pharmacological study of liposome-entrapped NDDP administered intrapleurally in patients with malignant pleural effusions.

W. Hong, R. Perez-soler, A. Khokhar, 1997, Clinical cancer research : an official journal of the American Association for Cancer Research.

Retrovirus–mediated wild–type P53 gene transfer to tumors of patients with lung cancer.

W. Hong, J. Roth, J. Lee, 1996, Nature Medicine.

Chemoprevention of aerodigestive tract cancers.

Edward S. Kim, F. Khuri, W. Hong, 2002, Annual review of medicine.

Treatment of former smokers with 9-cis-retinoic acid reverses loss of retinoic acid receptor-beta expression in the bronchial epithelium: results from a randomized placebo-controlled trial.

Diane D. Liu, J. Minna, F. Khuri, 2003, Journal of the National Cancer Institute.

The use of retinoids in head and neck cancer

R. Lotan, W. Hong, S. Schantz, 1987 .

Fluorouracil, doxorubicin, cyclophosphamide, and cisplatin combination chemotherapy in advanced or recurrent salivary gland carcinoma.

W. Hong, S. Legha, I. Dimery, 1990, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

New DNA Methylation Markers and Global DNA Hypomethylation Are Associated with Oral Cancer Development

Edward S. Kim, Jing Wang, S. Lippman, 2015, Cancer Prevention Research.

Cancer prevention science and practice.

S. Lippman, W. Hong, W. Hong, 2002, Cancer research.

Perspectives in Cancer Research Cancer Prevention Science and Practice 1

S. Lippman, W. Hong, W. Hong, 2002 .

Clonal genetic alterations in the lungs of current and former smokers.

J S Lee, S. Lippman, F. Khuri, 1997, Journal of the National Cancer Institute.

The Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor ZD1839 (Iressa) Suppresses c-Src and Pak1 Pathways and Invasiveness of Human Cancer Cells

C. J. Barnes, R. Lotan, W. Hong, 2004, Clinical Cancer Research.

Differential expression profiling of head and neck squamous carcinoma: significance in their phenotypic and biological classification

W. Hong, J. Lee, G. Clayman, 2002, Oncogene.

Multiregion gene expression profiling reveals heterogeneity in molecular subtypes and immunotherapy response signatures in lung cancer

P. A. Futreal, Jing Wang, W. Hong, 2018, Modern Pathology.

Effects of N-(4-hydroxyphenyl)retinamide on hTERT expression in the bronchial epithelium of cigarette smokers.

W. Hong, R. Morice, C. Moon, 2002, Journal of the National Cancer Institute.

Author Correction: Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma

P. A. Futreal, K. Ashizawa, Xin Hu, 2019, Nature Communications.

Progress in Chemoprevention Drug Development: The Promise of Molecular Biomarkers for Prevention of Intraepithelial Neoplasia and Cancer—A Plan to Move Forward

G. Mills, S. Lam, M. Spitz, 2006, Clinical Cancer Research.

Cyclin D1 genotype, response to biochemoprevention, and progression rate to upper aerodigestive tract cancer.

Diane D. Liu, W. Hong, J. Lee, 2003, Journal of the National Cancer Institute.

A novel polymorphism in human cytosine DNA-methyltransferase-3B promoter is associated with an increased risk of lung cancer.

Hongbing Shen, M. Spitz, W. Hong, 2002, Cancer research.

Expression of Epidermal Growth Factor Receptor , Polyamine Levels , Ornithine Decarboxylase Activity , Micronuclei , and Transglutaminase I in a 7 , 12-Dimethylbenz ( a ) anthracene-induced Hamster Buccal Pouch Carcinogenesis Model 1

T. Slaga, R. Lotan, W. Hong, 2006 .

Suppression of epidermal growth factor receptor, mitogen-activated protein kinase, and Pak1 pathways and invasiveness of human cutaneous squamous cancer cells by the tyrosine kinase inhibitor ZD1839 (Iressa).

C. J. Barnes, W. Hong, M. Mandal, 2003 .

Sex Determining Region Y-Box 2 (SOX2) Is a Potential Cell-Lineage Gene Highly Expressed in the Pathogenesis of Squamous Cell Carcinomas of the Lung

John D. Minna, Humam Kadara, Yang Xie, 2010, PloS one.

Clinical Outcomes and Biomarker Profiles of Elderly Pretreated NSCLC Patients from the BATTLE Trial

J Jack Lee, Edward S. Kim, Ignacio Wistuba, 2012, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Histopathologic findings after cis-platinum bleomycin therapy in advanced previously untreated head and neck carcinoma.

S. Shapshay, W. Hong, M. Strong, 1978, American journal of surgery.

Oral cancer prevention and the evolution of molecular-targeted drug development.

J. Sudbø, S. Lippman, W. Hong, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Phenotype and genotype of advanced premalignant head and neck lesions after chemopreventive therapy.

S. Lippman, W. Hong, J. Lee, 1998, Journal of the National Cancer Institute.

Loss of Fhit is frequent in stage I non-small cell lung cancer and in the lungs of chronic smokers.

F. Khuri, W. Hong, L. Mao, 1999, Cancer research.

Correlation between insulin-like growth factor-binding protein-3 promoter methylation and prognosis of patients with stage I non-small cell lung cancer.

Li Mao, Fadlo R Khuri, Diane D. Liu, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Biomarkers as Intermediate Endpoints in Chemoprevention Trials: Biological Basis of Lung Cancer Prevention

W. Hong, V. Papadimitrakopoulou, 1998 .

Identification and validation of metastasis-associated proteins in head and neck cancer cell lines by two-dimensional electrophoresis and mass spectrometry

Li Mao, Wei Hu, Weiguo Wu, 2004, Clinical & Experimental Metastasis.

Biomarkers in upper aerodigestive tract tumorigenesis: a review.

W. Hong, W. Hittelman, D. Shin, 1994, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Prognostic factors in resected stage I non-small-cell lung cancer: a multivariate analysis of six molecular markers.

Li Mao, B Nebiyou Bekele, Fadlo R Khuri, 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Concomitant targeting of the mTOR/MAPK pathways: novel therapeutic strategy in subsets of RICTOR/KRAS-altered non-small cell lung cancer

James X. Sun, Jing Wang, J. Minna, 2018, Oncotarget.

Activation of insulin-like growth factor 1 receptor in patients with non-small cell lung cancer

Edward S. Kim, Diane D. Liu, S. Lippman, 2015, Oncotarget.

Loss of Fhit expression is a predictor of poor outcome in tongue cancer.

W. Hong, J. Soria, L. Mao, 2001, Cancer research.

Synchronous Overexpression of Epidermal Growth Factor Receptor and HER2-neu Protein Is a Predictor of Poor Outcome in Patients with Stage I Non-Small Cell Lung Cancer

Roy S Herbst, Waun K Hong, Arlene M Correa, 2004, Clinical Cancer Research.

Personalizing lung cancer prevention through a reverse migration strategy.

Edward S. Kim, W. Hong, I. Wistuba, 2013, Topics in current chemistry.

Focus on head and neck cancer.

W. Hong, L. Mao, V. Papadimitrakopoulou, 2004, Cancer cell.

Microenvironment and Immunology CXCR 2 Expression inTumorCells Is aPoorPrognosticFactor and Promotes Invasion and Metastasis in Lung Adenocarcinoma

Edward S. Kim, Diane D. Liu, S. Lippman, 2013 .

XPA polymorphism associated with reduced lung cancer risk and a modulating effect on nucleotide excision repair capacity.

M. Spitz, W. Hong, Xifeng Wu, 2003, Carcinogenesis.

A myeloperoxidase polymorphism associated with reduced risk of lung cancer.

M. Spitz, W. Hong, Xifeng Wu, 2002, Lung cancer.

Polymorphism of DNA ligase I and risk of lung cancer--a case-control analysis.

Hongbing Shen, M. Spitz, W. Hong, 2002, Lung cancer.

p53 Genotypes and Haplotypes Associated With Lung Cancer Susceptibility and Ethnicity.

M. Spitz, S. Shete, W. Hong, 2002, Journal of the National Cancer Institute.

The association of microsomal epoxide hydrolase polymorphisms and lung cancer risk in African-Americans and Mexican-Americans.

C I Amos, M. Spitz, W. Hong, 2001, Carcinogenesis.

Polymorphisms of methylene-tetrahydrofolate reductase and risk of lung cancer: a case-control study.

Hongbing Shen, M. Spitz, W. Hong, 2001, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Case-control study of the D2 dopamine receptor gene and smoking status in lung cancer patients.

M. Spitz, W. Hong, Xifeng Wu, 1998, Journal of the National Cancer Institute.

Differential expression of E-cadherin and type IV collagenase genes predicts outcome in patients with stage I non-small cell lung carcinoma.

C. Bucana, F. Khuri, W. Hong, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

Fingerprinting the circulating repertoire of antibodies from cancer patients

Kim-Anh Do, Christopher J. Logothetis, Massimo Cristofanilli, 2003, Nature Biotechnology.

Dysregulation of epidermal growth factor receptor expression in premalignant lesions during head and neck tumorigenesis.

W. Hong, W. Hittelman, D. Shin, 1994, Cancer research.

Effects of insulin-like growth factor binding protein-3 and farnesyltransferase inhibitor SCH66336 on Akt expression and apoptosis in non-small-cell lung cancer cells.

Lin Ji, Hojin Moon, Fadlo R Khuri, 2004, Journal of the National Cancer Institute.

Predictive Biomarkers and Personalized Medicine Comprehensive Biomarker Analysis and Final Ef fi cacy Results of Sorafenib in the BATTLE Trial

Edward S. Kim, Jing Wang, J. Minna, 2013 .

Gene Expression Signature–Based Prognostic Risk Score in Gastric Cancer

Jae Yong Cho, Jae Ho Cheong, Eun Sung Park, 2011, Clinical Cancer Research.

Hypermethylation of the death-associated protein (DAP) kinase promoter and aggressiveness in stage I non-small-cell lung cancer.

F. Khuri, W. Hong, J. Lee, 2000, Journal of the National Cancer Institute.

Epidermal growth factor receptor and K‐Ras mutations and resistance of lung cancer to insulin‐like growth factor 1 receptor tyrosine kinase inhibitors

Edward S. Kim, S. Lippman, W. Hong, 2012, Cancer.

Elevated epithelial insulin-like growth factor expression is a risk factor for lung cancer development.

Edward S. Kim, Y. Miller, S. Lippman, 2009, Cancer research.

Elevated PDGFRB gene copy number gain is prognostic for improved survival outcomes in resected malignant pleural mesothelioma.

W. Hong, I. Wistuba, J. Lee, 2014, Annals of diagnostic pathology.

Integrative proteomic and transcriptomic analysis provides evidence for TrkB (NTRK2) as a therapeutic target in combination with tyrosine kinase inhibitors for non-small cell lung cancer

Jing Wang, W. Hong, I. Wistuba, 2018, Oncotarget.

Liposomal Encapsulation of Deguelin: Evidence for Enhanced Antitumor Activity in Tobacco Carcinogen–Induced and Oncogenic K-ras–Induced Lung Tumorigenesis

W. Hong, Ho-Yyoung Lee, J. Woo, 2009, Cancer Prevention Research.

Effects of deguelin on the phosphatidylinositol 3-kinase/Akt pathway and apoptosis in premalignant human bronchial epithelial cells.

R. Lotan, W. Hong, J. Pezzuto, 2003, Journal of the National Cancer Institute.

Germline genetic variations in drug action pathways predict clinical outcomes in advanced lung cancer treated with platinum-based chemotherapy

Joe Y. Chang, M. Spitz, Hushan Yang, 2008, Pharmacogenetics and genomics.

Frequent abnormalities of FHIT, a candidate tumor suppressor gene, in head and neck cancer cell lines.

W. Hong, L. Mao, R. Lotan, 1996, Cancer research.

Cyclin D1 and Cancer Development in Laryngeal Premalignancy Patients

Diane D. Liu, S. Lippman, W. Hong, 2009, Cancer Prevention Research.

Met Receptor Tyrosine Kinase and Chemoprevention of Oral Cancer

Edward S. Kim, S. Lippman, W. Hong, 2018, Journal of the National Cancer Institute.

Discordant p53 gene mutations in primary head and neck cancers and corresponding second primary cancers of the upper aerodigestive tract.

W. Hong, T. Mukhopadhyay, A. Casson, 1993, Cancer research.

Aberrant promoter methylation of multiple genes in bronchial brush samples from former cigarette smokers.

Diane D. Liu, W. Hong, J. Lee, 2002, Cancer research.

DPC4, a candidate tumor suppressor gene, is altered infrequently in head and neck squamous cell carcinoma.

R. Lotan, W. Hong, L. Mao, 1996, Cancer research.

Nuclear factor‐κB (nf‐κB) is frequently expressed in lung cancer and preneoplastic lesions

Bharat B. Aggarwal, Ignacio I. Wistuba, Shishir Shishodia, 2006 .

Stress hormones promote EGFR inhibitor resistance in NSCLC: Implications for combinations with β-blockers

Edward S. Kim, Diane D. Liu, Jing Wang, 2017, Science Translational Medicine.

Localization of chromosome 8p regions involved in early tumorigenesis of oral and laryngeal squamous carcinoma

W. Hong, J. Batsakis, J. Kagan, 1998, Oncogene.

All-trans-retinoic Acid Increases Transforming Growth Factor-β2 and Insulin-like Growth Factor Binding Protein-3 Expression through a Retinoic Acid Receptor-α-dependent Signaling Pathway*

W. Hong, J. Kurie, P. Cohen, 1997, The Journal of Biological Chemistry.

The tobacco-specific carcinogen-operated calcium channel promotes lung tumorigenesis via IGF2 exocytosis in lung epithelial cells

W. Hong, I. Wistuba, J. Lee, 2016, Nature Communications.

A Novel Derivative of the Natural Agent Deguelin for Cancer Chemoprevention and Therapy

Gordon Mills, Yoo-Shin Kim, Woo-Young Kim, 2008, Cancer Prevention Research.

Intratumoral Genetic Heterogeneity in Primary Head and Neck Squamous Carcinoma Using Microsatellite Markers

W. Hong, J. Batsakis, H. Goepfert, 1997, Diagnostic molecular pathology : the American journal of surgical pathology, part B.

Dysregulated cyclin D1 expression early in head and neck tumorigenesis: in vivo evidence for an association with subsequent gene amplification

W. Hong, Xia Li, W. Hittelman, 1998, Oncogene.

Plasma levels of insulin-like growth factor-I and lung cancer risk: a case-control analysis.

M. Spitz, W. Hong, Xifeng Wu, 1999, Journal of the National Cancer Institute.

Prospective study of combination chemotherapy with cyclophosphamide, doxorubicin, and cisplatin for unresectable or metastatic malignant pleural mesothelioma

W. Hong, F. Fossella, G. Walsh, 1995, Cancer.

Acute Pneumonitis Associated with MOPP Chemotherapy of Hodgkin's Disease

R. J. Cersosimo, W. Hong, S. J. Matthews, 1984, Drug intelligence & clinical pharmacy.

Implication of AMP-activated protein kinase and Akt-regulated survivin in lung cancer chemopreventive activities of deguelin.

W. Hong, I. Wistuba, C. Behrens, 2007, Cancer research.

ΔNp63 Overexpression, Alone and in Combination with Other Biomarkers, Predicts the Development of Oral Cancer in Patients with Leukoplakia

Edward S. Kim, S. Lippman, W. Hong, 2009, Clinical Cancer Research.

Susceptibility and Prevention Δ Np 63 Overexpression , Alone and in Combination with Other Biomarkers , Predicts the Development of Oral Cancer in Patients with Leukoplakia

Edward S. Kim, S. Lippman, W. Hong, 2009 .

Clinicopathologic Characteristics of the EGFR Gene Mutation in Non–small Cell Lung Cancer

M. Spitz, W. Hong, J. Roth, 2006, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Retinoic acid receptor- and retinoid X receptor-selective retinoids activate signaling pathways that converge on AP-1 and inhibit squamous differentiation in human bronchial epithelial cells.

R. Lotan, W. Hong, J. Nesbitt, 1996, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

The BATTLE-2 Study: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small-Cell Lung Cancer.

Li Shen, John V Heymach, Kevin R Coombes, 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Adenovirus-mediated p53 gene transfer in patients with advanced recurrent head and neck squamous cell carcinoma.

S. Lippman, W. Hong, J. Roth, 1998, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Chemoprevention of Cancer

Edward S. Kim, W. Hong, A. Tsao, 2004, CA: a cancer journal for clinicians.

Repair of tobacco carcinogen-induced DNA adducts and lung cancer risk: a molecular epidemiologic study.

M. Spitz, W. Hong, Q. Wei, 2000, Journal of the National Cancer Institute.

Fenretinide Activity in Retinoid-Resistant Oral Leukoplakia

S. Lippman, F. Khuri, R. Lotan, 2006, Clinical Cancer Research.

An attenuated adenovirus, ONYX-015, as mouthwash therapy for premalignant oral dysplasia.

C. Rudin, S. Lippman, W. Hong, 2003, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Functional outcomes following treatment for advanced laryngeal cancer. Part I--Voice preservation in advanced laryngeal cancer. Part II--Laryngectomy rehabilitation: the state of the art in the VA System. Research Speech-Language Pathologists. Department of Veterans Affairs Laryngeal Cancer Study Gr

W. Hong, G. Wolf, S. Fisher, 1998, The Annals of otology, rhinology & laryngology. Supplement.

Biomarker‐Integrated Neoadjuvant Dasatinib Trial in Resectable Malignant Pleural Mesothelioma

Jing Wang, W. Hong, I. Wistuba, 2017, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Inhibition of c-Src expression and activation in malignant pleural mesothelioma tissues leads to apoptosis, cell cycle arrest, and decreased migration and invasion

Ignacio Wistuba, W. Hong, I. Wistuba, 2007, Molecular Cancer Therapeutics.

Phase II study of 10-ethyl-10-deaza-aminopterin (10-EdAM; CGP 30 694) for stage IIIB or IV non-small cell lung cancer

W. Hong, H. Libshitz, J. S. Lee, 1990, Investigational New Drugs.

Adding Erlotinib to Chemoradiation Improves Overall Survival but not Progression-Free Survival in Stage III Non-Small-Cell Lung Cancer

Diane D. Liu, W. Hong, I. Wistuba, 2015, International journal of radiation oncology, biology, physics.

Prediction of Survival in Resected Non–Small Cell Lung Cancer Using a Protein Expression–Based Risk Model: Implications for Personalized Chemoprevention and Therapy

Edward S. Kim, Diane D. Liu, W. Hong, 2013, Clinical Cancer Research.

Retinoids and chemoprevention: Clinical and basic studies

S. Lippman, W. Hong, J. Kurie, 1995, Journal of cellular biochemistry. Supplement.

Patterns of relapse in locally advanced head and neck cancer patients who achieved complete remission after combined modality therapy

S. Shapshay, W. Hong, M. Strong, 1985, Cancer.

Feasibility of Image-Guided Transthoracic Core-Needle Biopsy in the BATTLE Lung Trial

Edward S. Kim, S. Lippman, W. Hong, 2013, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Therapeutic Target for Overcoming EGFR Inhibitor Resistance Resistance to EGFR and PI 3 K Inhibitors and Identifies Axl as a Mesenchymal Transition Gene Signature Predicts

Edward S. Kim, J. Weinstein, K. Coombes, 2012 .

Expression of vascular endothelial growth factor and microvessel density in head and neck tumorigenesis.

W. Hong, J. Lee, W. Hittelman, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

IMPACT (Imaging and Molecular Markers for Patients with Lung Cancer: Approaches with Molecular Targets and Complementary, Innovative and Therapeutic Modalities)

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Prospective study of the pulmonary toxicity of continuously infused bleomycin.

W. Hong, K. R. Cooper, W. Hong, 1981, Cancer treatment reports.

Epirubicin: a review of the pharmacology, clinical activity, and adverse effects of an adriamycin analogue.

R. J. Cersosimo, W. Hong, W K Hong, 1986, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Second primary tumors in patients with upper aerodigestive tract cancers: joint effects of smoking and alcohol (United States)

M. Spitz, F. Khuri, W. Hong, 2003, Cancer Causes & Control.

A Novel Small-Molecule Inhibitor Targeting CREB-CBP Complex Possesses Anti-Cancer Effects along with Cell Cycle Regulation, Autophagy Suppression and Endoplasmic Reticulum Stress

W. Hong, J. Koo, R. Herbst, 2015, PloS one.

The dynamics of gene expression changes in a mouse model of oral tumorigenesis may help refine prevention and treatment strategies in patients with oral cancer

S. Lippman, W. Hong, J. Lachuer, 2016, Oncotarget.

Induction of p53-regulated genes and tumor regression in lung cancer patients after intratumoral delivery of adenoviral p53 (INGN 201) and radiation therapy.

J. Gu, F. Khuri, W. Hong, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Effect of retinoic acid on DNA cleavage and cytotoxicity of topoisomerase II-reactive drugs in a human head and neck squamous carcinoma cell line.

W. Hong, L. Zwelling, D. Chan, 1989, Cancer research.

Receptor Tyrosine Kinase EphA5 Is a Functional Molecular Target in Human Lung Cancer

Diane D. Liu, R. Sidman, W. Hong, 2015, The Journal of Biological Chemistry.

Association of a p73 exon 2 G4C14-to-A4T14 polymorphism with risk of squamous cell carcinoma of the head and neck.

M. Spitz, W. Hong, Q. Wei, 2004, Carcinogenesis.

A novel C/T polymorphism in the core promoter of human de novo cytosine DNA methyltransferase 3B6 is associated with prognosis in head and neck cancer.

Edward S. Kim, W. Hong, L. Mao, 2004, International journal of oncology.

Genome-wide association study of survival in non-small cell lung cancer patients receiving platinum-based chemotherapy.

Jian Gu, Joe Y. Chang, Yuanqing Ye, 2011, Journal of the National Cancer Institute.

All-trans retinoic acid converts E2F into a transcriptional suppressor and inhibits the growth of normal human bronchial epithelial cells through a retinoic acid receptor- dependent signaling pathway.

W. Hong, M. Andreeff, J. Kurie, 1998, The Journal of clinical investigation.

Association between the V109G Polymorphism of the p27 Gene and the Risk and Progression of Oral Squamous Cell Carcinoma

M. Spitz, W. Hong, Q. Wei, 2004, Clinical Cancer Research.

Association between the V 109 G Polymorphism of the p 27 Gene and the Risk and Progression of Oral Squamous Cell Carcinoma

M. Spitz, W. Hong, Q. Wei, 2004 .

Alleviation by leucovorin of the dose-limiting toxicity of edatrexate: potential for improved therapeutic efficacy

W. Hong, J. S. Lee, W. Murphy, 2004, Cancer Chemotherapy and Pharmacology.

Benzo[a]pyrene diol epoxide and bleomycin sensitivity and susceptibility to cancer of upper aerodigestive tract.

M. Spitz, W. Hong, Xifeng Wu, 1998, Journal of the National Cancer Institute.

Joint Effect of Mutagen Sensitivity and Insulin-Like Growth Factors in Predicting the Risk of Developing Secondary Primary Tumors and Tumor Recurrence in Patients with Head and Neck Cancer

M. Spitz, J. Gu, W. Hong, 2006, Clinical Cancer Research.

The BATTLE to Personalize Lung Cancer Prevention through Reverse Migration

Edward S. Kim, W. Hong, I. Wistuba, 2011, Cancer Prevention Research.

Frequent expression of MAGE1 tumor antigens in bronchial epithelium of smokers without lung cancer.

Diane D. Liu, W. Hong, J. Lee, 2011, Experimental and therapeutic medicine.

Mechanisms underlying lack of insulin-like growth factor-binding protein-3 expression in non-small-cell lung cancer

F. Khuri, W. Hong, Y. Chang, 2004, Oncogene.

Phase II study of induction chemotherapy with paclitaxel, ifosfamide, and carboplatin (TIC) for patients with locally advanced squamous cell carcinoma of the head and neck

A. Garden, S. Lippman, F. Khuri, 2002, Cancer.

Methylenetetrahydrofolate reductase polymorphisms and risk of squamous cell carcinoma of the head and neck: A case‐control analysis

Hongbing Shen, M. Spitz, S. Shete, 2005, International journal of cancer.

Phase II trial of 5,6-dihydro-5-azacytidine in pleural malignant mesothelioma

W. Hong, R. Winn, M. Raber, 1991, Investigational New Drugs.

Clinical significance of insulin-like growth factor-binding protein-3 expression in stage I non-small cell lung cancer.

Diane D. Liu, F. Khuri, W. Hong, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Phase II trial of 13-cis-retinoic acid plus interferon-alpha in recurrent head and neck cancer.

R. Weber, S. Lippman, W. Hong, 1993, Investigational new drugs.

INDUCTION CHEMOTHERAPY OF ADVANCED PREVIOUSLY UNTREATED SQUAMOUS CELL HEAD AND NECK CANCER WITH CISPLATIN AND BLEOMYCIN

S. Shapshay, W. Hong, S. Strong, 1980 .

Preoperative adjuvant induction chemotherapy in head and neck cancer

S. Shapshay, W. Hong, J. Popkin, 1984 .

Prognostic indicators in induction cis-platinum bleomycin chemotherapy for advanced head and neck cancer.

S. Shapshay, W. Hong, A. Sismanis, 1980, American journal of surgery.

Combination of cis‐platinum and bleomycin prior to surgery and/or radiotherapy compared with radiotherapy alone for the treatment of advanced squamous cell carcinoma of the head and neck

S. Shapshay, W. Hong, C. Vaughan, 1982, Cancer.

Association of levels of circulating C1q binding macromolecules with induction chemotherapy response in head and neck cancer patients.

W. Hong, R. Rossen, H. Savage, 1988, Cancer research.

Induction bleomycin infusion in head and neck cancer

W. Hong, M. Strong, C. Vaughan, 1984, American journal of clinical oncology.

Treatment of previously untreated stage III and IV squamous cell carcinoma of the head and neck.

S. Shapshay, W. Hong, 1980, Otolaryngologic clinics of North America.

Identification of Insulin-Like Growth Factor Binding Protein-3 as a Farnesyl Transferase Inhibitor SCH66336-Induced Negative Regulator of Angiogenesis in Head and Neck Squamous Cell Carcinoma

F. Khuri, W. Hong, P. Cohen, 2006, Clinical Cancer Research.

Evaluation of Difluoromethylornithine for the Chemoprevention of Barrett's Esophagus and Mucosal Dysplasia

W. Hong, R. Broaddus, E. Gerner, 2011, Cancer Prevention Research.

Phase II study of carboplatin and edatrexate (10-EdAM) with leucovorin rescue for patients with recurrent squamous cell carcinoma of the head and neck

S. Lippman, W. Hong, I. Dimery, 2004, Investigational New Drugs.

Immune-Modulation by Epidermal Growth Factor Receptor Inhibitors: Implication on Anti-Tumor Immunity in Lung Cancer

W. Hong, R. Perez-soler, C. Haymaker, 2016, PloS one.

The influence of cytoreductive surgery on the response to chemotherapy of a rat renal cancer

W. Hong, C. Olsson, R. deVere White, 2004, Urological Research.

The Effect of Diethyldithiocarbamate (DDTC) on Response, Toxicity and Pharmacology of Cisplatin in Patients with Recurrent Squamous Cell Carcinoma of the Head and Neck

W. Hong, R. Newman, I. Dimery, 1988 .

Phase I/II trial of radiation with chemotherapy "boost" for advanced squamous cell carcinomas of the head and neck: toxicities and responses.

A. Garden, K. Ang, S. Lippman, 1999, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Multiple primary cancer in patients with cancer of the head and neck: second cancer of the head and neck, esophagus, and lung.

M. Spitz, W. Hong, J. Licciardello, 1989, International journal of radiation oncology, biology, physics.

Plasma exchange in six patients with advanced cancers of the head and neck

W. Hong, M. Strong, C. Vaughan, 1985, Journal of clinical apheresis.

Interleukin-11 Receptor Is a Candidate Target for Ligand-Directed Therapy in Lung Cancer: Analysis of Clinical Samples and BMTP-11 Preclinical Activity.

R. Sidman, Menghong Sun, W. Hong, 2016, The American journal of pathology.

Squamous Carcinoma Cell Line Topoisomerase II-reactive Drugs in a Human Head and Neck Effect of Retinoic Acid on DNA Cleavage and Cytotoxicity of Updated Version

W. Hong, Hoon Kim, L. Zwelling, 2006 .

Effect of Retinoic Acid on DNA Cleavage and Cytotoxicity of Topoisomerase II-reactive Drugs in a Human Head and Neck Squamous Carcinoma Cell Line 1

W. Hong, Hoon Kim, L. Zwelling, 2006 .

Retinoids as antitumor agents: a new age of biological therapy.

W. Hong, J. Kurie, W. Hong, 1999, The cancer journal from Scientific American.

Phase I Trial of Weekly Topotecan and Gemcitabine in Patients With Solid Tumors

Edward S. Kim, S. Lippman, F. Khuri, 2009, American journal of clinical oncology.

Mutagen sensitivity to benzo(a)pyrene diol epoxide and the risk of squamous cell carcinoma of the head and neck.

M. Spitz, W. Hong, E. Sturgis, 1998, Clinical cancer research : an official journal of the American Association for Cancer Research.

Epidermal growth factor receptor-targeted therapy with C225 and cisplatin in patients with head and neck cancer.

F. Khuri, W. Hong, R. Perez-soler, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Epidermal growth factor receptor-targeted therapy with C225 and cisplatin in patients with head and neck cancer.

F. Khuri, W. Hong, D. Shin, 2001, Clinical Cancer Research.

Epidermal Growth Factor Receptor Expression in Head and Neck Tumorigenesis and Saturation of EGFR with Monoclonal Antibody RG83852

W. Hong, R. Perez-soler, W. Hittelman, 1997 .

Membrane Carbonic Anhydrase IX Expression and Relapse Risk in Resected Stage I–II Non–Small-Cell Lung Cancer

Diane D. Liu, W. Hong, J. Roth, 2014, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Phase II study of topotecan in patients with non-small cell lung cancer

W. Hong, R. Perez-soler, M. Raber, 1993 .

Polymorphisms of FAS and FAS Ligand Genes Involved in the Death Pathway and Risk and Progression of Squamous Cell Carcinoma of the Head and Neck

M. Spitz, W. Hong, Q. Wei, 2006, Clinical Cancer Research.

Continuous vindesine infusion in advanced head and neck cancer

W. Hong, M. Strong, C. Vaughan, 1983, American journal of clinical oncology.

Increased retinoic acid responsiveness in lung carcinoma cells that are nonresponsive despite the presence of endogenous retinoic acid receptor (RAR) beta by expression of exogenous retinoid receptors retinoid X receptor alpha, RAR alpha, and RAR gamma.

W. Hong, R. Lotan, W K Hong, 2001, Cancer research.

Differential impacts of insulin-like growth factor-binding protein-3 (IGFBP-3) in epithelial IGF-induced lung cancer development.

W. Hong, I. Wistuba, J. Lee, 2011, Endocrinology.

Sensitivity to DNA damage induced by benzo(a)pyrene diol epoxide and risk of lung cancer: a case-control analysis.

M. Spitz, W. Hong, Q. Wei, 2001, Cancer research.

Reduced DNA repair capacity in head and neck cancer patients.

M. Spitz, W. Hong, Q. Wei, 1998, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Reduced expression of hMLH1 and hGTBP/hMSH6: a risk factor for head and neck cancer.

M. Spitz, W. Hong, S. Strom, 1998, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

The prognostic role of loss of insulin-like growth factor-binding protein-3 expression in head and neck carcinogenesis.

Diane D. Liu, W. Hong, V. Papadimitrakopoulou, 2006, Cancer letters.

Reduced DNA Repair Capacity for Removing Tobacco Carcinogen–Induced DNA Adducts Contributes to Risk of Head and Neck Cancer but not Tumor Characteristics

M. Spitz, R. Weber, S. Lippman, 2010, Clinical Cancer Research.

Chemoprevention of respiratory tract cancer.

F. Khuri, W. Hong, J. Kurie, 1997, Hematology/oncology clinics of North America.

Genetic Variants in Inflammation-Related Genes Are Associated with Radiation-Induced Toxicity Following Treatment for Non-Small Cell Lung Cancer

Joe Y. Chang, M. Spitz, J. Minna, 2010, PloS one.

Molecular epidemiology and retinoid chemoprevention of head and neck cancer.

M. Spitz, S. Lippman, F. Khuri, 1997, Journal of the National Cancer Institute.

Hypoxia-inducible factor 1alpha and antiangiogenic activity of farnesyltransferase inhibitor SCH66336 in human aerodigestive tract cancer.

Edward S. Kim, W. Hong, Ji-Youn Han, 2005, Journal of the National Cancer Institute.

Identification and validation of differences in protein levels in normal, premalignant, and malignant lung cells and tissues using high-throughput Western Array and immunohistochemistry.

R. Lotan, W. Hong, I. Wistuba, 2006, Cancer research.

Immunohistochemical Expression of Basic Fibroblast Growth Factor and Fibroblast Growth Factor Receptors 1 and 2 in the Pathogenesis of Lung Cancer

R. Lotan, W. Hong, I. Wistuba, 2008, Clinical Cancer Research.

Proliferative changes in the bronchial epithelium of former smokers treated with retinoids.

Diane D. Liu, J. Minna, F. Khuri, 2007, Journal of the National Cancer Institute.

A pilot double-blind, randomized, placebo-controlled trial of curcumin/bioperine for lung cancer chemoprevention in patients with chronic obstructive pulmonary disease

Diane D. Liu, W. Hong, I. Wistuba, 2013 .

Biological Activity of Celecoxib in the Bronchial Epithelium of Current and Former Smokers

Edward S. Kim, Diane D. Liu, R. Lotan, 2010, Cancer Prevention Research.

Impact of Smoking Cessation on Global Gene Expression in the Bronchial Epithelium of Chronic Smokers

Li Mao, J Jack Lee, Li Zhang, 2005, Cancer Prevention Research.

Variant alleles of the D2 dopamine receptor gene and obesity

Christopher I. Amos, Margaret R. Spitz, Xifeng Wu, 2000 .

13-cis-retinoic acid plus interferon-α2a in recurrent respiratory papillomatosis

R. Weber, S. Lippman, W. Hong, 1994 .

Epidermal growth factor receptor, cyclooxygenase-2, and BAX expression in the primary non-small cell lung cancer and brain metastases.

W. Hong, J. Roth, T. McDonnell, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Visualization of the timing of gene amplification during multistep head and neck tumorigenesis.

W. Hong, M. Tainsky, W. Hittelman, 2000, Cancer research.

Clinical development plans for cancer chemopreventive agents

G. Omenn, V. Steele, W. Hong, 1996 .

Gender differences in p53 mutational status in small cell lung cancer.

W. Hong, L. Mao, J. Ro, 1999, Cancer research.

Advances in Brief Gender Differences in p 53 Mutational Status in Small Cell Lung Cancer 1

Diane D. Liu, W. Hong, L. Mao, 1999 .

Identification of two distinct tumor-suppressor loci on the long arm of chromosome 10 in small cell lung cancer

Li Mao, Waun K Hong, W. Hong, 1998, Oncogene.

Global Assessment of Genetic Variation Influencing Response to Retinoid Chemoprevention in Head and Neck Cancer Patients

Edward S. Kim, M. Spitz, J. Gu, 2011, Cancer Prevention Research.

Validation of a Novel Statistical Model for Assessing the Synergy of Combined-Agent Cancer Chemoprevention

R. Lotan, W. Hong, J. Lee, 2010, Cancer Prevention Research.

A phase I/II study of neoadjuvant chemotherapy followed by radiation with boost chemotherapy for advanced T-stage nasopharyngeal carcinoma.

A. Garden, K. Ang, F. Khuri, 2005, International journal of radiation oncology, biology, physics.

Predictors of Survival in Never-Smokers with Non–Small Cell Lung Cancer: A Large-Scale, Two-Phase Genetic Study

M. Spitz, J. Minna, S. Lippman, 2012, Clinical Cancer Research.

Strategy and planning for chemopreventive drug development: Clinical development plans II

G. Omenn, V. Steele, W. Hong, 1996, Journal of cellular biochemistry. Supplement.

A statistical analysis of the reliability and classification error in application of the mutagen sensitivity assay.

M. Spitz, W. Hong, J. Lee, 1996, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Nuclear retinoid acid receptor beta in bronchial epithelium of smokers before and during chemoprevention.

S. Lippman, R. Lotan, W. Hong, 1999, Journal of the National Cancer Institute.

Chemoprevention of lung cancer.

W. Hong, 1999, Oncology.

Characterizing the Molecular Spatial and Temporal Field of Injury in Early-Stage Smoker Non–Small Cell Lung Cancer Patients after Definitive Surgery by Expression Profiling

Edward S. Kim, K. Coombes, Jing Wang, 2012, Cancer Prevention Research.

THE MANAGEMENT OF SUPERIOR SULCUS TUMORS

W. Hong, J. Roth, C. Stevens, 2001 .

Clinical chemoprevention: developing a cancer prevention strategy.

W. Hong, S. Benner, 1993, Journal of the National Cancer Institute.

Development and Validation of a Lung Cancer Risk Prediction Model for African-Americans

M. Spitz, W. Hong, Q. Dong, 2008, Cancer Prevention Research.

Does induction chemotherapy have a role in the management of nasopharyngeal carcinoma? Results of treatment in the era of computerized tomography.

A. Garden, K. Ang, S. Lippman, 1996, International Journal of Radiation Oncology, Biology, Physics.

Inhibition of proliferation and induction of apoptosis in cervical carcinoma cells by retinoids: Implications for chemoprevention

W. Hong, D. Lotan, M. Mitchell, 1995, Journal of cellular biochemistry. Supplement.

PROSPECT (Profiling of Resistance Patterns & Oncogenic Signaling Pathways in Evaluation of Cancers of the Thorax and Therapeutic Target Identification)

W. Hong, D. Stewart, W. Hong, 2008 .

The evolution of treatment outcomes for resected stage IIIA non-small cell lung cancer over 16 years at a single institution.

W. Hong, J. Roth, S. Swisher, 2005, The Journal of thoracic and cardiovascular surgery.

Dose escalation of gemcitabine is possible with concurrent chest three-dimensional rather than two-dimensional radiotherapy: a phase I trial in patients with stage III non-small-cell lung cancer.

W. Hong, R. Herbst, R. Komaki, 2009, International journal of radiation oncology, biology, physics.

Cisplatin, ifosfamide, and prolonged oral etoposide in the treatment of patients with extensive small cell lung carcinoma

W. Hong, R. Perez-soler, F. Fossella, 1998, Cancer.

Inhibition of N-(4-hydroxyphenyl)retinamide-Induced Apoptosis in Breast Cancer Cells by Galectin-3

R. Lotan, W. Hong, Jin-Hyuk Choi, 2004, Cancer biology & therapy.

The synthetic heteroarotinoid SHetA2 induces apoptosis in squamous carcinoma cells through a receptor-independent and mitochondria-dependent pathway.

R. Lotan, W. Hong, K. Berlin, 2003, Cancer research.

Intra-tumor Heterogeneity in Localized Lung Adenocarcinomas Delineated by Multi-region Sequencing

Yuanqing Ye, Harshad Mahadeshwar, David C. Wedge, 2015 .

Phase I study of recombinant human endostatin in patients with advanced solid tumors.

L. Ellis, K. Hess, W. Hong, 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Cancer prevention by delay. Commentary re: J. A. O'Shaughnessy et al., Treatment and Prevention of Intraepithelial Neoplasia: An Important Target for Accelerated New Agent Development. Clin. Cancer Res., 8: 314-346, 2002.

S. Lippman, W. Hong, W. Hong, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Dual mechanisms of action of the retinoid CD437: nuclear retinoic acid receptor-mediated suppression of squamous differentiation and receptor-independent induction of apoptosis in UMSCC22B human head and neck squamous cell carcinoma cells.

R. Lotan, W. Hong, R. Lotan, 2000, Molecular pharmacology.

Chemoprvention traials in the cervix: Design, feasibility, and recruitment

Kenji Nishioka, W. Hong, R. Richards-Kortum, 1995, Journal of cellular biochemistry. Supplement.

An Attenuated Adenovirus , ONYX-015 , As Mouthwash Therapy for Premal ignant

C. Rudin, S. Lippman, W. Hong, 2003 .

Oral Premalignant Lesions Chromosome Polysomy and Histological Characteristics in Updated

S. Lippman, W. Hong, W. Hittelman, 2001 .

Primary chemotherapy of advanced head and neck cancer: where do we go from here?

W. Hong, B. Glisson, W. Hong, 1996, Journal of the National Cancer Institute.

p 53 Expression : Predicting Recurrence and Second Primary Tumors in Head and Neck Squamous Cell Carcinoma

S. Lippman, W. Hong, J. Lee, 1996 .

Recent advances in head and neck cancer--larynx preservation and cancer chemoprevention: the Seventeenth Annual Richard and Hinda Rosenthal Foundation Award Lecture.

S. Lippman, W. Hong, G. Wolf, 1993, Cancer research.

Concomitant DFMO and sulindac chemoprevention of colorectal adenomas: a major clinical advance

M. Sporn, W. Hong, 2008, Nature Clinical Practice Oncology.

Insulin-like growth factor binding protein-6 activates programmed cell death in non-small cell lung cancer cells

W. Hong, J. Roth, J. Kurie, 2000, Oncogene.

All-trans-Retinoic Acid Inhibits Jun N-terminal Kinase-dependent Signaling Pathways*

W. Hong, J. Kurie, M. Dawson, 1998, The Journal of Biological Chemistry.

Genetic Variants in the PI3K/PTEN/AKT/mTOR Pathway Predict Head and Neck Cancer Patient Second Primary Tumor/Recurrence Risk and Response to Retinoid Chemoprevention

Edward S. Kim, M. Spitz, S. Lippman, 2012, Clinical Cancer Research.

Predictive Biomarkers and Personalized Medicine Genetic Variants in the PI 3 K / PTEN / AKT / mTOR Pathway Predict Head and Neck Cancer Patient Second Primary Tumor / Recurrence Risk and Response to Retinoid Chemoprevention

Edward S. Kim, M. Spitz, S. Lippman, 2012 .

A Phase II Study of Lonafarnib (SCH66336) in Patients With Chemorefractory, Advanced Squamous Cell Carcinoma of the Head and Neck

Edward S. Kim, F. Khuri, W. Hong, 2009, American journal of clinical oncology.

Expression of Interleukin-1 Receptor–Associated Kinase-1 in Non–Small Cell Lung Carcinoma and Preneoplastic Lesions

R. Lotan, W. Hong, I. Wistuba, 2009, Clinical Cancer Research.

Biomarkers in chemoprevention for upper aerodigestive tract tumors.

W. Hong, D. Shin, J. Ro, 1994, Yonsei medical journal.

Intermediate end point markers in chemoprevention trials of lung cancer

S. Lippman, W. Hong, R. Morice, 1997 .

Phase II multicenter study of the epidermal growth factor receptor antibody cetuximab and cisplatin for recurrent and refractory squamous cell carcinoma of the head and neck.

W. Hong, R. Herbst, E. Vokes, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Targeting heat shock protein 90 overrides the resistance of lung cancer cells by blocking radiation-induced stabilization of hypoxia-inducible factor-1alpha.

W. Hong, Ho-Yyoung Lee, S. Oh, 2009, Cancer research.

Involvement of mitochondrial and Akt signaling pathways in augmented apoptosis induced by a combination of low doses of celecoxib and N-(4-hydroxyphenyl) retinamide in premalignant human bronchial epithelial cells.

R. Lotan, W. Hong, D. Lotan, 2006, Cancer research.

Phase 2 study of carboplatin, docetaxel, and bevacizumab as frontline treatment for advanced nonsmall‐cell lung cancer

Edward S. Kim, Diane D. Liu, G. Gladish, 2010, Cancer.

Association between glutathione S‐transferase π polymorphisms and survival in patients with advanced nonsmall cell lung carcinoma

Joe Y. Chang, M. Spitz, W. Hong, 2006, Cancer.

P-484 Synchronous overexpression of epidermal growth factor receptor and HER2-NEU is a predictor of poor outcome in patients with stage I non-small cell lung cancer

C. Bucana, W. Hong, R. Herbst, 2003 .

Cervical human papillomavirus infection and intraepithelial neoplasia: a review.

M F Mitchell, R Richards-Kortum, W. Hong, 1996, Journal of the National Cancer Institute. Monographs.

Enhanced growth inhibition and apoptosis induction in NSCLC cell lines by combination of celecoxib and 4HPR at clinically relevant concentrations

R. Lotan, W. Hong, Shi-Yong Sun, 2005, Cancer biology & therapy.

A randomized double-blind study of the biological effects of celecoxib as a chemopreventive agent in current and former smokers

Edward S. Kim, Diane D. Liu, W. Hong, 2008 .

Phase II study of combination cisplatin, docetaxel and erlotinib in patients with metastatic/recurrent head and neck squamous cell carcinoma (HNSCC)

Edward S. Kim, S. Lippman, W. Hong, 2005 .

Continuous cisplatin (24‐hour) and 5‐fluorouracil (120‐hour) infusion in recurrent head and neck squamous cell carcinoma

W. Hong, I. Dimery, R. Byers, 1988, Cancer.

Identification of novel antiangiogenic anticancer activities of deguelin targeting hypoxia‐inducible factor‐1 alpha

W. Hong, Ho-Yyoung Lee, S. Oh, 2008, International journal of cancer.

Immunohistochemical overexpression of platelet-derived growth factor receptor-beta (PDGFR-β) is associated with PDGFRB gene copy number gain in sarcomatoid non-small-cell lung cancer.

W. Hong, I. Wistuba, J. Lee, 2011, Clinical lung cancer.

Prognostic impact of insulin receptor expression on survival of patients with nonsmall cell lung cancer

Edward S. Kim, Diane D. Liu, S. Lippman, 2012, Cancer.

Recent advances in cancer chemoprevention.

S. Lippman, R. Lotan, W. Hong, 1991, Cancer cells.

Phase I S tudy o f R ecombinant H uman E ndostatin i n Patients W ith A dvanced S olid T umors

L. Ellis, K. Hess, W. Hong, 2002 .

No Association between hOGG1 Ser326Cys polymorphism and risk of squamous cell carcinoma of the head and neck.

M. Spitz, W. Hong, Q. Wei, 2004, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Effects of insulin-like growth factor binding protein-3 and farnesyltransferase inhibitor SCH66336 on Akt expression and apoptosis in non-small-cell lung cancer cells.

F. Khuri, R. Lotan, W. Hong, 2004, Journal of the National Cancer Institute.

Retinoids in oncology

R. Lotan, W. Hong, W. Hong, 1993 .

O-112 A phase I/II study of the anti-VEGF MAb bevacizumab (Avastin™) and erlotinib (Tarceva™), a HER1/EGFR-TK inhibitor: a multi-faceted approach for the treatment of recurrent non-small cell lung cancer

Edward S. Kim, W. Hong, R. Herbst, 2003 .

The current status of docetaxel in solid tumors. An M. D. Anderson Cancer Center Review.

W. Hong, 2002, Oncology.

Prevention of lung cancer. The new millennium.

F. Khuri, W. Hong, E. Kim, 2000, Chest surgery clinics of North America.

Growth of Non-Small Cell Lung Cancer Insulin-like Growth Factor Binding Protein-3 Inhibits the Updated Version

W. Hong, J. Kurie, P. Cohen, 2002 .