Y. Michotte

发表

Determination of the enantiomeric purity of dexfenfluramine by capillary electrophoresis: use of a Plackett—Burman design for the optimization of the separation

Y. Heyden, S. Boonkerd, M. Detaevernier, 1996 .

Increased hippocampal noradrenaline is a biomarker for efficacy of vagus nerve stimulation in a limbic seizure model

R. Raedt, E. Carrette, Y. Michotte, 2011, Journal of neurochemistry.

The evolution of serum astroglial S-100 beta protein in patients with cardiac arrest treated with mild hypothermia.

Y. Michotte, G. Ebinger, M. Zizi, 2005, Resuscitation.

Chiral separation of cetirizine by capillary electrophoresis

Y. Michotte, A. Van Eeckhaut, 2006, Electrophoresis.

Chiral separations by capillary electrophoresis: Recent developments and applications

Y. Michotte, A. Van Eeckhaut, 2006, Electrophoresis.

In Vivo Study of the Effect of Valpromide and Valnoctamide in the Pilocarpine Rat Model of Focal Epilepsy

Y. Michotte, M. Bialer, I. Smolders, 2000, Pharmaceutical Research.

Differential modulations of striatal tyrosine hydroxylase and dopamine metabolism by cannabinoid agonists as evidence for functional selectivity in vivo

Y. Michotte, E. Hermans, G. Muccioli, 2012, Neuropharmacology.

Revisiting the complex influences of cannabinoids on motor functions unravels pharmacodynamic differences between cannabinoid agonists

Y. Michotte, I. Smolders, E. Hermans, 2010, Neuropharmacology.

Neurochemical changes and laser Doppler flowmetry in the endothelin-1 rat model for focal cerebral ischemia

Y. Michotte, I. Smolders, G. Ebinger, 2000, Brain Research.

Rat hippocampal somatostatin sst3 and sst4 receptors mediate anticonvulsive effects in vivo: Indications of functional interactions with sst2 receptors

Y. Michotte, I. Smolders, J. Portelli, 2011, Neuropharmacology.

Load dependency and reliability of microhardness measurements on acid-etched enamel surfaces.

D. Coomans, Y. Michotte, R. Cleymaet, 1992, Dental materials : official publication of the Academy of Dental Materials.

The Significance of Homovanillic Acid and 3,4‐Dihydroxyphenylacetic Acid Concentrations in Human Lumbar Cerebrospinal Fluid

Y. Michotte, G. Ebinger, P. Herregodts, 1987, Journal of neurochemistry.

Strategies to reduce aspecific adsorption of peptides and proteins in liquid chromatography-mass spectrometry based bioanalyses: an overview.

Y. Michotte, K. Maes, I. Smolders, 2014, Journal of chromatography. A.

Development of an On‐Line Electrochemical Biosensor for Glucose Determination in Rat Brain Using Microdialysis Sampling

Y. Michotte, M. Pravda, J. Kauffmann, 2000 .

Study of a new solid carbon paste tyrosinase-modified amperometric biosensor for the determination of catecholamines by high-performance liquid chromatography

Y. Michotte, K. Vytras, M. Pravda, 1996 .

Mild hypothermia reduces activated caspase-3 up to 1 week after a focal cerebral ischemia induced by endothelin-1 in rats

Y. Michotte, S. Hachimi-Idrissi, R. Kooijman, 2013, Brain Research.

The dual role of the neuroinflammatory response after ischemic stroke: modulatory effects of hypothermia

Y. Michotte, S. Hachimi-Idrissi, R. Kooijman, 2010, Journal of Neuroinflammation.

Combined ion-pair extraction and high-performance liquid chromatography for the determination of the biogenic amines and their major metabolites in single brain tissue samples.

Y. Michotte, G. Ebinger, P. Herregodts, 1987, Journal of chromatography.

The control of kainic acid-induced status epilepticus

Y. Michotte, I. Smolders, A. Massie, 2010, Epilepsy Research.

Quantitative in Vivo Microdialysis Study on the Influence of Multidrug Transporters on the Blood-Brain Barrier Passage of Oxcarbazepine: Concomitant Use of Hippocampal Monoamines as Pharmacodynamic Markers for the Anticonvulsant Activity

Y. Michotte, A. Meurs, I. Smolders, 2005, Journal of Pharmacology and Experimental Therapeutics.

Benserazide decreases central AADC activity, extracellular dopamine levels and levodopa decarboxylation in striatum of the rat

Y. Michotte, G. Ebinger, S. Sarre, 2001, Journal of Neural Transmission.

Quantitative microdialysis for the in vivo measurement of carbamazepine, oxcarbazepine and their major metabolites in rat brain- and liver tissue and in blood using the internal standard technique

Y. Michotte, G. Ebinger, S. Sarre, 1995 .

In vitro and in vivo microdialysis calibration for the measurement of carbamazepine and its metabolites in rat brain tissue using the internal reference technique

Y. Michotte, G. Ebinger, S. Sarre, 1993, Journal of Neuroscience Methods.

The use of microdialysis for the determination of plasma protein binding of drugs.

Y. Michotte, I. Smolders, S. Sarre, 1992, Journal of pharmaceutical and biomedical analysis.

Proteomic analysis of global protein expression changes in the endothelin-1 rat model for cerebral ischemia: Rescue effect of mild hypothermia

L. Arckens, Y. Michotte, M. Vinken, 2013, Neurochemistry International.

Insulin-Like Growth Factor I: A Potential Neuroprotective Compound for the Treatment of Acute Ischemic Stroke?

Y. Michotte, J. De Keyser, R. Kooijman, 2009, Stroke.

Mild hypothermia causes differential, time-dependent changes in cytokine expression and gliosis following endothelin-1-induced transient focal cerebral ischemia

Y. Michotte, S. Hachimi-Idrissi, R. Kooijman, 2011, Journal of Neuroinflammation.

Spontaneously hypertensive rats display reduced microglial activation in response to ischemic stroke and lipopolysaccharide

Y. Michotte, J. De Keyser, R. Kooijman, 2012, Journal of Neuroinflammation.

The adaptation of the human thyroid gland to a physiological regimen of iodide intake: evidence for a transitory inhibition of thyroid hormone secretion modulated by the intrathyroidal iodine stores

F. Deconinck, Y. Michotte, M. Jonckheer, 1983, Journal of endocrinological investigation.

Direct enhancement of hippocampal dopamine or serotonin levels as a pharmacodynamic measure of combined antidepressant–anticonvulsant action

Y. Michotte, A. Meurs, I. Smolders, 2008, Neuropharmacology.

Cellular targets for angiotensin II fragments: pharmacological and molecular evidence

Y. Michotte, G. Vauquelin, I. Smolders, 2002, Journal of the renin-angiotensin-aldosterone system : JRAAS.

Intrathecal lidocaine elevates prostaglandin E2 levels in cerebrospinal fluid: a microdialysis study in freely moving rats.

Y. Michotte, I. Smolders, F. Camu, 2008, British journal of anaesthesia.

Translocation of the insulin‐regulated aminopeptidase to the cell surface: detection by radioligand binding

Y. Michotte, G. Vauquelin, P. Vanderheyden, 2008, British journal of pharmacology.

Involvement of insulin-regulated aminopeptidase in the effects of the renin–angiotensin fragment angiotensin IV: a review

Y. Michotte, G. Vauquelin, I. Smolders, 2008, Heart Failure Reviews.

Use of microbore LC-MS/MS for the quantification of oxcarbazepine and its active metabolite in rat brain microdialysis samples.

Y. Michotte, I. Smolders, R. Clinckers, 2006, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Capillary and nano-liquid chromatography-tandem mass spectrometry for the quantification of small molecules in microdialysis samples: comparison with microbore dimensions.

Y. Michotte, I. Smolders, A. Van Eeckhaut, 2006, Journal of chromatography. A.

Seizure activity and changes in hippocampal extracellular glutamate, GABA, dopamine and serotonin

Y. Michotte, A. Meurs, I. Smolders, 2008, Epilepsy Research.

Synergistic modulation of cystinyl aminopeptidase by divalent cation chelators.

Y. Michotte, V. Kersemans, G. Vauquelin, 2004, Biochemical pharmacology.

Antidepressant-like effects of oxytocin in mice are dependent on the presence of insulin-regulated aminopeptidase.

Y. Michotte, I. Smolders, P. Gard, 2013, The international journal of neuropsychopharmacology.

Proconvulsive effects of oxytocin in the generalized pentylenetetrazol mouse model are mediated by vasopressin 1a receptors

Y. Michotte, I. Smolders, A. Schallier, 2012, Brain Research.

Acute versus long-term effects of 6-hydroxydopamine on oxidative stress and dopamine depletion in the striatum of mice

Y. Michotte, V. Baekelandt, S. Sarre, 2011, Journal of Neuroscience Methods.

Dopaminergic neurons of system xc–‐deficient mice are highly protected against 6‐hydroxydopamine‐induced toxicity

N. Plesnila, Y. Michotte, I. Smolders, 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The use of capillary gas chromatography/mass spectrometry for the determination of acidic dopamine metabolites in human brain.

Y. Michotte, D. Deleu, G. Ebinger, 1985, Biomedical mass spectrometry.

In vivo pharmacokinetics of levodopa and 3-O-methyldopa in muscle

Y. Michotte, D. Deleu, G. Ebinger, 1991, Naunyn-Schmiedeberg's Archives of Pharmacology.

In vivo pharmacokinetics of levodopa and 3-O-methyldopa in muscle

Y. Michotte, D. Deleu, G. Ebinger, 1991, Naunyn-Schmiedeberg's Archives of Pharmacology.

Simultaneous in vivo microdialysis in plasma and skeletal muscle: a study of the pharmacokinetic properties of levodopa by noncompartmental analysis.

Y. Michotte, D. Deleu, G. Ebinger, 1994, Journal of pharmaceutical sciences.

The effect of carbidopa and entacapone pretreatment on the L-dopa pharmacokinetics and metabolism in blood plasma and skeletal muscle in beagle dog: an in vivo microdialysis study.

Y. Michotte, D. Deleu, G. Ebinger, 1995, The Journal of pharmacology and experimental therapeutics.

Involvement of CRH Receptors in the Neuroprotective Action of R-Apomorphine in the Striatal 6-OHDA Rat Model

Y. Michotte, S. Sarre, Eduard Bentea, 2013 .

Clinical and pharmacokinetic comparison of oral and duodenal delivery of levodopa/carbidopa in patients with Parkinson's disease with a fluctuating response to levodopa

Y. Michotte, D. Deleu, G. Ebinger, 2004, European Journal of Clinical Pharmacology.

The effect of carbidopa on the pharmacokinetics and metabolism of intravenously administered levodopa in blood plasma and skeletal muscle

Y. Michotte, D. Deleu, G. Ebinger, 1993, Naunyn-Schmiedeberg's Archives of Pharmacology.

Substantia Nigra Is an Anticonvulsant Site of Action of Topiramate in the Focal Pilocarpine Model of Limbic Seizures

Y. Michotte, A. Meurs, I. Smolders, 2006, Epilepsia.

The role of the central renin-angiotensin system in Parkinson’s disease

Y. Michotte, P. Vanderheyden, S. Sarre, 2010, Journal of the renin-angiotensin-aldosterone system : JRAAS.

Histological, behavioural and neurochemical evaluation of medial forebrain bundle and striatal 6-OHDA lesions as rat models of Parkinson's disease

Y. Michotte, G. Ebinger, S. Sarre, 2005, Journal of Neuroscience Methods.

Catechol is the major product of salicylate hydroxylation in 1-methyl-4-phenylpyridinium ion treated rats

Y. Michotte, S. Sarre, N. Verbeke, 1998, European Journal of Drug Metabolism and Pharmacokinetics.

Effects of venlafaxine on extracellular 5-HT, dopamine and noradrenaline in the hippocampus and on peripheral hormone concentrations in the rat in vivo.

Y. Michotte, R. Meeusen, M. Piacentini, 2003, Life sciences.

Determination of amino acids associated with cerebral ischaemia in rat brain microdialysates using narrowbore liquid chromatography and fluorescence detection

Y. Michotte, I. Smolders, A. Hemelrijck, 2005, Journal of Neuroscience Methods.

Direct angiotensin II type 2 receptor stimulation decreases dopamine synthesis in the rat striatum

Y. Michotte, P. Vanderheyden, S. Sarre, 2010, Neuropharmacology.

Ion-pair ultra-high performance liquid chromatographic analysis of monoamines: peak-splitting at high flow rates.

Y. Michotte, K. Maes, A. Van Eeckhaut, 2013, Journal of chromatography. A.

UHPLC with electrochemical detection for the quantitative determination of monoamines in microdialysis samples

Y. Michotte, A. Eeckhaut, H. Brouwer, 2012 .

S-100 protein as early predictor of regaining consciousness after out of hospital cardiac arrest.

Y. Michotte, J. Schiettecatte, G. Ebinger, 2002, Resuscitation.

Continuous intravenous monitoring of levodopa and 3-O-methyldopa by microdialysis and high-performance liquid chromatography with electrochemical detection.

Y. Michotte, D. Deleu, G. Ebinger, 1991, Journal of pharmaceutical and biomedical analysis.

Clinical and pharmacokinetic evaluation of controlled-release levodopa/carbidopa (CR-4) in parkinsonian patients with severe motor fluctuations: a six month follow-up study

Y. Michotte, D. Deleu, G. Ebinger, 1989, Clinical Neurology and Neurosurgery.

Basal and Tolbutamide‐induced Plasma Somatostatin in Healthy Subjects and in Patients with Diabetes and Impaired Glucose Tolerance

Y. Michotte, G. Somers, O. Segers, 1989, Diabetic medicine : a journal of the British Diabetic Association.

Effect of bupropion on hippocampal neurotransmitters and on peripheral hormonal concentrations in the rat.

Y. Michotte, R. Meeusen, M. Piacentini, 2003, Journal of applied physiology.

High-performance liquid chromatography with electrochemical detection for the determination of levodopa, catecholamines and their metabolites in rat brain dialysates.

Y. Michotte, D. Deleu, G. Ebinger, 1992, Journal of chromatography.

The analysis of excitatory, inhibitory and other amino acids in rat brain microdialysates using microbore liquid chromatography

Y. Michotte, I. Smolders, G. Ebinger, 1995, Journal of Neuroscience Methods.

A Potential Neuroprotective Compound for the Treatment of Acute Ischemic Stroke?

Y. Michotte, J. Keyser, R. Kooijman, 2009 .

Distribution of apomorphine enantiomers in plasma, brain tissue and striatal extracellular fluid.

Y. Michotte, S. Sarre, N. Verbeke, 1997, European journal of pharmacology.

Time-dependent changes in GLT-1 functioning in striatum of hemi-Parkinson rats

Y. Michotte, C. Meshul, A. Massie, 2010, Neurochemistry International.

Inactivation of the Constitutively Active Ghrelin Receptor Attenuates Limbic Seizure Activity in Rodents

G. Collingridge, Z. Bortolotto, Y. Michotte, 2012, Neurotherapeutics.

Selective labeling of IRAP by the tritiated AT4 receptor ligand [3H]Angiotensin IV and its stable analog [3H]AL-11

Y. Michotte, G. Vauquelin, S. Chakravarthy, 2009, Molecular and Cellular Endocrinology.

Involvement of insulin-regulated aminopeptidase and/or aminopeptidase N in the angiotensin IV-induced effect on dopamine release in the striatum of the rat

Y. Michotte, G. Vauquelin, I. Smolders, 2007, Brain Research.

Microbore liquid chromatography with UV detection to study the in vivo passage of compound 21, a non-peptidergic AT2 receptor agonist, to the striatum in rats

Y. Michotte, A. Eeckhaut, R. Clinckers, 2011, Journal of Neuroscience Methods.

Deletion of insulin-regulated aminopeptidase in mice decreases susceptibility to pentylenetetrazol-induced generalized seizures

Y. Michotte, I. Smolders, P. Vanderheyden, 2011, Seizure.

Metabolism of angiotensin II is required for its in vivo effect on dopamine release in the striatum of the rat

Y. Michotte, G. Vauquelin, G. Ebinger, 2004, Journal of neurochemistry.

The chemical composition of idiopathic nonarteriosclerotic cerebral calcifications

D. Massart, Y. Michotte, J. Smeyers-Verbeke, 1975, Neurology.

Effectiveness of vigabatrin against focally evoked pilocarpine-induced seizures and concomitant changes in extracellular hippocampal and cerebellar glutamate, gamma-aminobutyric acid and dopamine levels, a microdialysis-electrocorticography study in freely moving rats.

Y. Michotte, J. Manil, I. Smolders, 1997, The Journal of pharmacology and experimental therapeutics.

The effects of LY393613, nimodipine and verapamil, in focal cerebral ischaemia.

Y. Michotte, M. O'Neill, I. Smolders, 2001, European journal of pharmacology.

Separation of neutral dihydropyridines and their enantiomers using electrokinetic chromatography.

M. Detaevernier, Y. Michotte, A. Van Eeckhaut, 2004, Journal of pharmaceutical and biomedical analysis.

Prediction of antiepileptic drug efficacy: the use of intracerebral microdialysis to monitor biophase concentrations

Y. Michotte, M. Danhof, R. Voskuyl, 2009, Expert opinion on drug metabolism & toxicology.

A morphological and chemical study of calcification of the pineal gland

D. Massart, Y. Michotte, A. Lowenthal, 1977, Journal of Neurology.

Quantification of piritramide in human colostrum

Y. Michotte, J. Poelaert, A. Van Eeckhaut, 2017, Journal of clinical pharmacy and therapeutics.

Peripheral inflammation modifies the effect of intrathecal IL-1β on spinal PGE2 production mainly through cyclooxygenase-2 activity. A spinal microdialysis study in freely moving rats

Y. Michotte, I. Smolders, F. Camu, 2006, Pain.

Neostigmine influences the l-dopa-induced extracellular dopamine levels in the striatum

Y. Michotte, G. Ebinger, S. Sarre, 2000, Brain Research.

The inheritance of plasma and red blood cell magnesium and zinc levels studied from twin and family data.

Y. Michotte, P. Darlu, J. Henrotte, 1981, Acta geneticae medicae et gemellologiae.

Abnormal Fatty Acid Turnover in the Phospholipids of the Red Blood Cell Membranes of Cystic Fibrosis Patients (in Vitro Study)

Y. Michotte, V. Rogiers, A. Vercruysse, 1984, Pediatric Research.

Development and Testing of Bioadhesive, Fluoride‐containing Slow‐release Tablets for Oral Use

D. Coomans, J. Remon, Y. Michotte, 1991, The Journal of pharmacy and pharmacology.

Brain calcification in a case of acute lymphoblastic leukaemia

D. Massart, Y. Michotte, J. Smeyers-Verbeke, 1975, Journal of the Neurological Sciences.

A morphological and chemical study of calcification of the choroid plexus

D. Massart, Y. Michotte, A. Lowenthal, 1977, Journal of Neurology.

Anticonvulsant effect and neurotransmitter modulation of focal and systemic 2-chloroadenosine against the development of pilocarpine-induced seizures

Y. Michotte, I. Smolders, G. Ebinger, 2000, Neuropharmacology.

NMDA receptor‐mediated pilocarpine‐induced seizures: characterization in freely moving rats by microdialysis

Y. Michotte, J. Manil, I. Smolders, 1997, British journal of pharmacology.

Using microdialysis to analyse the passage of monovalent nanobodies through the blood–brain barrier

Y. Michotte, S. Muyldermans, P. De Baetselier, 2012, British journal of pharmacology.

Critical Evaluation of Acetylcholine Determination in Rat Brain Microdialysates using Ion-Pair Liquid Chromatography with Amperometric Detection

Sophie Sarre, Yvette Michotte, Y. Michotte, 2008, Sensors.

Endogenous cystinyl aminopeptidase in Chinese hamster ovary cells: characterization by [125I]Ang IV binding and catalytic activity.

Veerle Kersemans, Minh Tam Le, Patrick Vanderheyden, 2004, Biochemical pharmacology.

Neuroprotective and neurotrophic effect of apomorphine in the striatal 6-OHDA-lesion rat model of Parkinson's disease

Y. Michotte, G. Ebinger, S. Sarre, 2004, Brain Research.

Development and evaluation of a linear regression method for the prediction of maximal chiral separation of basic drug racemates by cyclodextrin-mediated capillary zone electrophoresis.

S. Boonkerd, M. Detaevernier, Y. Michotte, 2000, Journal of chromatography. A.

Validation of bioanalytical LC-MS/MS assays: evaluation of matrix effects.

Y. Michotte, I. Smolders, A. Van Eeckhaut, 2009, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Quantitative liquid chromatography/mass spectrometry for the analysis of microdialysates.

Y. Michotte, I. Smolders, S. Sarre, 2008, Talanta.

Differential effects of organic modifiers on the enantioseparation of dimetindene maleate with carboxymethyl-beta-cyclodextrin in capillary electrophoresis.

M. Detaevernier, Y. Michotte, J. Crommen, 2004, Journal of separation science.

Use of capillary electrophoresis for the determination of vitamins of the B group in pharmaceutical preparations

S. Boonkerd, M. Detaevernier, Y. Michotte, 1994 .

Matrix effects in the determination of copper and manganese in biological materials using carbon furnace atomic absorption spectrometry

D. Massart, Y. Michotte, J. Smeyers-Verbeke, 1976 .

Comparison of the effects of intrathecal administration of levobupivacaine and lidocaine on the prostaglandin E2 and glutamate increases in cerebrospinal fluid: a microdialysis study in freely moving rats.

Y. Michotte, I. Smolders, J. Poelaert, 2009, British journal of anaesthesia.

Formalin-induced spinal glutamate release in freely moving rats: comparison of two spinal microdialysis approaches.

Y. Michotte, F. Camu, M. Zizi, 2004, Acta anaesthesiologica Belgica.

Suppression of chiral recognition of 3-hydroxy-1,4-benzodiazepines during micellar electrokinetic capillary chromatography with bile salts.

S. Boonkerd, M. Detaevernier, J. Vindevogel, 1995, Journal of chromatography. A.

Rehardening of surface softened and surface etched enamel in vitro and by intraoral exposure.

D. Coomans, Y. Michotte, R. Cleymaet, 1993, Caries research.

IN VITRO DISSOLUTION OF TWO ORAL CONTROLLED RELEASE PREPARATIONS OF DICLOFENAC SODIUM

M. Detaevernier, Y. Michotte, P. Wilder, 1991 .

Atrophic autoimmune thyroiditis: relationship between the clinical state and intrathyroidal iodine as measured in vivo in man.

F. Deconinck, Y. Michotte, M. Jonckheer, 1981, The Journal of clinical endocrinology and metabolism.

Anticonvulsant action of hippocampal dopamine and serotonin is independently mediated by D2 and 5‐HT1A receptors

Y. Michotte, A. Meurs, I. Smolders, 2004, Journal of neurochemistry.

Determination of the biogenic amines and their major metabolites in single human brain tissue samples using a combined extraction procedure and high-performance liquid chromatography with electrochemical detection.

Y. Michotte, G. Ebinger, P. Herregodts, 1985, Journal of chromatography.

Influence of some matrix elements on the determination of copper and manganese by furnace atomic absorption spectrometry

D. Massart, Y. Michotte, J. Smeyers-Verbeke, 1978 .

Monoaminergic neurotransmitters in Alzheimer's disease An HPLC study comparing presenile familial and sporadic senile cases

Y. Michotte, J. Keyser, G. Ebinger, 1989, Journal of Neurological Sciences.

Regional differences in the distribution of norepinephrine and epinephrine in human cerebral cortex: A neurochemical study using HPLC and electrochemical detection

Y. Michotte, G. Ebinger, P. Herregodts, 1989, Neuroscience Letters.

Distribution of biogenic amines and their catabolites in brains from patients with Alzheimer's disease

Y. Michotte, J. Martín, P. Cras, 1987, Journal of the Neurological Sciences.

Separation and simultaneous determination of the components in an analgesic tablet formulation by micellar electrokinetic chromatography

S. Boonkerd, M. Detaevernier, Y. Michotte, 1995 .

Migration behaviour of benzodiazepines in micellar electrokinetic chromatography

S. Boonkerd, M. Detaevernier, J. Vindevogel, 1996 .

Development of a validated capillary electrophoresis method for enantiomeric purity testing of dexchlorpheniramine maleate.

M. Detaevernier, Y. Michotte, A. Van Eeckhaut, 2002, Journal of chromatography. A.

Hippocampal and cerebellar extracellular amino acids during pilocarpine-induced seizures in freely moving rats.

Y. Michotte, I. Smolders, G. Ebinger, 1997, European journal of pharmacology.

The absolute quantification of endogenous levels of brain neuropeptides in vivo using LC-MS/MS.

Y. Michotte, K. Maes, I. Smolders, 2011, Bioanalysis.

Biotransformation of locally applied precursors of dopamine, serotonin and noradrenaline in striatum and hippocampus: A microdialysis study

Y. Michotte, I. Smolders, G. Ebinger, 2005, Journal of Neural Transmission.

Flumazenil prevents diazepam-elicited anticonvulsant action and concomitant attenuation of glutamate overflow.

Y. Michotte, I. Smolders, G. Ebinger, 2000, European journal of pharmacology.

Effects of diazepam on extracellular brain neurotransmitters in pilocarpine-induced seizures in rats.

Y. Michotte, J. Manil, I. Smolders, 1999, European journal of pharmacology.

Relation between lead in surface tooth enamel, blood, and saliva from children residing in the vicinity of a non-ferrous metal plant in Belgium.

D. Coomans, Y. Michotte, R. Cleymaet, 1991, British journal of industrial medicine.

A comparative study of the lead and cadmium content of surface enamel of Belgian and Kenyan children.

D. Coomans, Y. Michotte, R. Cleymaet, 1991, The Science of the total environment.

Capillary gas chromatographic determination of vincamine in plasma.

D. Massart, Y. Michotte, 1985, Journal of chromatography.

Nigral proteasome inhibition in mice leads to motor and non-motor deficits and increased expression of Ser129 phosphorylated α-synuclein

Y. Michotte, V. Baekelandt, I. Smolders, 2015, Front. Behav. Neurosci..

Longitudinal follow-up and characterization of a robust rat model for Parkinson's disease based on overexpression of alpha-synuclein with adeno-associated viral vectors

R. D'Hooge, Y. Michotte, G. Bormans, 2015, Neurobiology of Aging.

Determination of reboxetine in rat brain microdialysates and plasma samples using liquid chromatography coupled to fluorescence detection.

Y. Michotte, R. Clinckers, A. Van Eeckhaut, 2012, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Microdialysis as a Tool to Unravel Neurobiological Mechanisms of Seizures and Antiepileptic Drug Action

Y. Michotte, I. Smolders, R. Clinckers, 2011 .

Oxidative Stress in Genetic Mouse Models of Parkinson's Disease

Y. Michotte, S. Sarre, Eduard Bentea, 2012, Oxidative medicine and cellular longevity.

In vivo characterization of the angiotensin‐(1–7)‐induced dopamine and γ‐aminobutyric acid release in the striatum of the rat

Y. Michotte, G. Ebinger, S. Sarre, 2005, The European journal of neuroscience.

Effects of tryptophan and/or acute running on extracellular 5-HT and 5-HIAA levels in the hippocampus of food-deprived rats

Y. Michotte, R. Meeusen, F. Chaouloff, 1996, Brain Research.

Postischemic mild hypothermia reduces neurotransmitter release and astroglial cell proliferation during reperfusion after asphyxial cardiac arrest in rats

Y. Michotte, A. Michotte, I. Smolders, 2004, Brain Research.

Nano-LC-MS/MS for the monitoring of angiotensin IV in rat brain microdialysates: limitations and possibilities.

Y. Michotte, I. Smolders, S. Sarre, 2007, Journal of separation science.

Convulsant and Subconvulsant Doses of Norfloxacin in the Presence and Absence of Biphenylacetic Acid Alter Extracellular Hippocampal Glutamate but Not Gamma-Aminobutyric Acid Levels in Conscious Rats

Y. Michotte, W. Couet, I. Smolders, 2002, Antimicrobial Agents and Chemotherapy.

Metabolic activation of quercetin mutagenicity.

Y. Michotte, A. Boeyé, R. Vrijsen, 1990, Mutation research.

Assessment of the convulsant liability of antidepressants using zebrafish and mouse seizure models

Y. Michotte, A. Crawford, I. Smolders, 2011, Epilepsy & Behavior.

Loss of System xc− Does Not Induce Oxidative Stress But Decreases Extracellular Glutamate in Hippocampus and Influences Spatial Working Memory and Limbic Seizure Susceptibility

Y. Michotte, I. Smolders, Joeri Van Liefferinge, 2011, The Journal of Neuroscience.

High‐affinity Na+/K+‐dependent glutamate transporter EAAT4 is expressed throughout the rat fore‐ and midbrain

L. Arckens, Y. Michotte, R. Mccullumsmith, 2008, The Journal of comparative neurology.

Region- and age-specific changes in glutamate transport in the AβPP23 mouse model for Alzheimer's disease.

Y. Michotte, A. Michotte, I. Smolders, 2011, Journal of Alzheimer's disease : JAD.

Chapter 5.3 The use of microdialysis for the study of neurological disorders

Y. Michotte, I. Smolders, 2006 .

Ghrelin: An emerging new anticonvulsant neuropeptide

Y. Michotte, I. Smolders, J. Portelli, 2012, Epilepsia.

Effect of M1- and M2-muscarinic drugs on striatal dopamine release and metabolism: an in vivo microdialysis study comparing normal and 6-hydroxydopamine-lesioned rats

Y. Michotte, G. Ebinger, S. Sarre, 1993, Brain Research.

Influence of brain catecholamines on the development of fatigue in exercising rats in the heat

Y. Michotte, R. Meeusen, M. Piacentini, 2008, The Journal of physiology.

Simultaneous determination of levodopa, carbidopa, 3-O-methyldopa and dopamine in plasma using high-performance liquid chromatography with electrochemical detection.

Y. Michotte, M. Moors, D. Deleu, 1987, Journal of pharmaceutical and biomedical analysis.

Serotonin Reuptake Inhibition by Citalopram in Rat Strains Differing for Their Emotionality

Y. Michotte, F. Chaouloff, G. Ebinger, 2000, Neuropsychopharmacology.

Low dose guanfacine once-a-day for the treatment of hypertension in general practice: A multi-centre pilot study

Y. Michotte, K. Westelinck, 1982 .

Antagonists of GLUK5-containing kainate receptors prevent pilocarpine-induced limbic seizures

G. Collingridge, Z. Bortolotto, Y. Michotte, 2002, Nature Neuroscience.

Ang II and Ang IV: Unraveling the Mechanism of Action on Synaptic Plasticity, Memory, and Epilepsy

Y. Michotte, I. Smolders, P. Vanderheyden, 2008, CNS neuroscience & therapeutics.

Cortistatin‐14 Mediates its Anticonvulsant Effects Via sst2 and sst3 but Not Ghrelin Receptors

Y. Michotte, G. Di Giovanni, I. Smolders, 2014, CNS neuroscience & therapeutics.

Acute dopamine/norepinephrine reuptake inhibition increases brain and core temperature in rats.

Romain Meeusen, Sophie Sarre, Hiroshi Hasegawa, 2005, Journal of applied physiology.

Neuropeptide Y increases in vivo hippocampal extracellular glutamate levels through Y1 receptor activation

Y. Michotte, A. Meurs, I. Smolders, 2012, Neuroscience Letters.

Astrocytic β2-adrenergic receptors: From physiology to pathology

Y. Michotte, N. Wilczak, J. Keyser, 2010, Progress in Neurobiology.

Mild hypothermia induced by a helmet device: a clinical feasibility study.

Y. Michotte, G. Ebinger, S. Hachimi-Idrissi, 2001, Resuscitation.

Hippocampal dopamine and serotonin elevations as pharmacodynamic markers for the anticonvulsant efficacy of oxcarbazepine and 10,11-dihydro-10-hydroxycarbamazepine

Y. Michotte, A. Meurs, I. Smolders, 2005, Neuroscience Letters.

Chapter 3.1 Liquid chromatographic methods used for microdialysis: an overview

Y. Michotte, S. Sarre, 2006 .

Involvement of the AT1 receptor subtype in the effects of angiotensin IV and LVV‐haemorphin 7 on hippocampal neurotransmitter levels and spatial working memory

Y. Michotte, G. Vauquelin, V. Caveliers, 2010, Journal of neurochemistry.

Sigma 1 receptor‐mediated increase in hippocampal extracellular dopamine contributes to the mechanism of the anticonvulsant action of neuropeptide Y

Y. Michotte, A. Meurs, I. Smolders, 2007, The European journal of neuroscience.

Intrastrain differences in seizure susceptibility, pharmacological response and basal neurochemistry of Wistar rats

Alfred Meurs, Yvette Michotte, Y. Michotte, 2009, Epilepsy Research.

Experimental and Clinical Use of Therapeutic Hypothermia for Ischemic Stroke: Opportunities and Limitations

Y. Michotte, S. Hachimi-Idrissi, S. Sarre, 2011, Stroke research and treatment.

Involvement of the somatostatin‐2 receptor in the anti‐convulsant effect of angiotensin IV against pilocarpine‐induced limbic seizures in rats

Y. Michotte, A. Meurs, I. Smolders, 2006, Journal of neurochemistry.

Muscarinic antagonists in substantia nigra influence the decarboxylation of L-dopa in striatum.

Y. Michotte, G. Ebinger, S. Sarre, 2000, European journal of pharmacology.

Biotransformation of l‐DOPA to Dopamine in the Substantia Nigra of Freely Moving Rats: Effect of Dopamine Receptor Agonists and Antagonists

Y. Michotte, G. Ebinger, S. Sarre, 1998, Journal of neurochemistry.

Development of Monoaminergic Neurotransmitters in Fetal and Postnatal Rat Brain: Analysis by HPLC with Electrochemical Detection

Y. Michotte, L. Vanhaelst, E. Hooghe-Peters, 1990, Journal of neurochemistry.

Influence of methanol on the enantioresolution of antihistamines with carboxymethyl‐β‐cyclodextrin in capillary electrophoresis

Y. Michotte, J. Crommen, A. Van Eeckhaut, 2004, Electrophoresis.

Anticonvulsant action of GBR-12909 and citalopram against acute experimentally induced limbic seizures

Y. Michotte, A. Meurs, I. Smolders, 2004, Neuropharmacology.

In vivo use of a dual acid etch biopsy for the evaluation of lead profiles in human surface enamel.

D. Coomans, Y. Michotte, R. Cleymaet, 1991, Caries Research.

VEGF modulates NMDA receptors activity in cerebellar granule cells through Src-family kinases before synapse formation

Paul Antoine Salin, P. Carmeliet, D. Schmucker, 2011, Proceedings of the National Academy of Sciences.

In Vivo Modulatory Action of Extracellular Glutamate on the Anticonvulsant Effects of Hippocampal Dopamine and Serotonin

Y. Michotte, A. Meurs, I. Smolders, 2005, Epilepsia.

LY377770, a novel iGlu5 kainate receptor antagonist with neuroprotective effects in global and focal cerebral ischaemia

Y. Michotte, P. Ornstein, M. O'Neill, 2000, Neuropharmacology.

In vivo neurochemical effects of the NR2B selective NMDA receptor antagonist CR 3394 in 6-hydroxydopamine lesioned rats.

Y. Michotte, F. Makovec, S. Sarre, 2008, European journal of pharmacology.

Acute running stimulates hippocampal dopaminergic neurotransmission in rats, but has no influence on brain-derived neurotrophic factor.

Y. Michotte, R. Meeusen, I. Bos, 2012, Journal of applied physiology.

Biotransformation of locally applied l-dopa in the corpus striatum of the hemi-Parkinsonian rat studied with microdialysis

Y. Michotte, G. Ebinger, S. Sarre, 1994, Naunyn-Schmiedeberg's Archives of Pharmacology.

Biotransformation of l-DOPA in striatum and substantia nigra of rats with a unilateral, nigrostriatal lesion: a microdialysis study

Y. Michotte, D. Deleu, G. Ebinger, 1992, Naunyn-Schmiedeberg's Archives of Pharmacology.

Endurance training effects on neurotransmitter release in rat striatum: an in vivo microdialysis study.

S Sarre, Y. Michotte, R. Meeusen, 1997, Acta physiologica Scandinavica.

Brain, liver and blood distribution kinetics of carbamazepine and its metabolic interaction with clomipramine in rats: a quantitative microdialysis study.

S Sarre, Y. Michotte, G. Ebinger, 1995, The Journal of pharmacology and experimental therapeutics.

Longitudinal follow-up and characterization of a robust rat model for Parkinson’s disease based on overexpression of alpha-synuclein with adeno-associated viral vectors. Authors:

Gijsbers, R. D'Hooge, Y. Michotte, 2015 .

Tonic GABA-ergic modulation of striatal dopamine release studied by in vivo microdialysis in the freely moving rat.

Y. Michotte, I. Smolders, G. Ebinger, 1995, European journal of pharmacology.

5-HT4 receptor involvement in the serotonin-enhanced dopamine efflux from the substantia nigra of the freely moving rat: a microdialysis study

Y. Michotte, G. Ebinger, K. Thorré, 1998, Brain Research.

Dopaminergic regulation of serotonin release in the substantia nigra of the freely moving rat using microdialysis

Y. Michotte, I. Smolders, G. Ebinger, 1998, Brain Research.

Muscarinic Modulation of Striatal Dopamine, Glutamate, and GABA Release, as Measured with In Vivo Microdialysis

Y. Michotte, I. Smolders, G. Ebinger, 1997, Journal of neurochemistry.

Reversible neurochemical changes mediated by delayed intrastriatal glial cell line‐derived neurotrophic factor gene delivery in a partial Parkinson's disease rat model

Y. Michotte, J. Brotchi, M. Levivier, 2009, The journal of gene medicine.

Simultaneous monitoring of levodopa, dopamine and their metabolites in skeletal muscle and subcutaneous tissue in different pharmacological conditions using microdialysis.

Y. Michotte, D. Deleu, G. Ebinger, 1993, Journal of pharmaceutical and biomedical analysis.

Levodopa biotransformation in hemi-Parkinson rats: effect of dopamine receptor agonists and antagonists.

Y. Michotte, G. Ebinger, S. Sarre, 1996, European journal of pharmacology.

Differential effects of restraint stress on hippocampal 5-HT metabolism and extracellular levels of 5-HT in streptozotocin-diabetic rats

Romain Meeusen, Sophie Sarre, Yvette Michotte, 1997, Brain Research.

NMDA receptor antagonism potentiates the l-DOPA-induced extracellular dopamine release in the subthalamic nucleus of hemi-parkinson rats

Y. Michotte, P. Deurwaerdère, I. Smolders, 2014, Neuropharmacology.

MK801 suppresses the l-DOPA-induced increase of glutamate in striatum of hemi-Parkinson rats

Y. Michotte, G. Ebinger, S. Sarre, 2002, Brain Research.

Molecular connectivity and retention indexes.

D L Massart, D. Massart, Y. Michotte, 1977, Journal of pharmaceutical sciences.

Extracellular Striatal Dopamine and Glutamate After Decortication and Kainate Receptor Stimulation, as Measured by Microdialysis

Y. Michotte, I. Smolders, G. Ebinger, 1996, Journal of neurochemistry.

Pharmacological and neurochemical characterization of the involvement of hippocampal adrenoreceptor subtypes in the modulation of acute limbic seizures

Y. Michotte, A. Meurs, I. Smolders, 2010, Journal of neurochemistry.

Controlled-release carbidopa/levodopa (CR) in parkinsonian patients with response fluctuations on standard levodopa treatment: clinical and pharmacokinetic observations.

Y. Michotte, D. Deleu, G. Ebinger, 1989, Neurology.

l-Theanine intake increases threshold for limbic seizures but decreases threshold for generalized seizures

Y. Michotte, I. Smolders, Joeri Van Liefferinge, 2013, Nutritional neuroscience.

Time-dependent changes in striatal xCT protein expression in hemi-Parkinson rats

Y. Michotte, I. Smolders, A. Massie, 2008, Neuroreport.

Effect of l-tryptophan, l-5-hydroxytryptophan and l-tryptophan prodrugs on the extracellular levels of 5-HT and 5-HIAA in the hippocampus of the rat using microdialysis

Y. Michotte, R. Meeusen, G. Ebinger, 1996 .

Reassessment of the antioxidative mixture for the challenging electrochemical determination of dopamine, noradrenaline and serotonin in microdialysis samples.

Y. Michotte, K. Maes, I. Smolders, 2015, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Microbore liquid chromatography analysis of monoamine transmitters.

Y. Michotte, S. Sarre, I. Smolders, 1997, Methods in molecular biology.

Microbore liquid chromatography analysis of amino acid transmitters.

Y. Michotte, G. Ebinger, S. Sarre, 1997, Methods in molecular biology.

Characterization of the extracellular serotonin release in the substantia nigra of the freely moving rat using microdialysis

Y. Michotte, G. Ebinger, S. Sarre, 1997, Brain Research.

New antioxidant mixture for long term stability of serotonin, dopamine and their metabolites in automated microbore liquid chromatography with dual electrochemical detection.

Y. Michotte, G. Ebinger, M. Pravda, 1997, Journal of chromatography. B, Biomedical sciences and applications.

Microbore liquid chromatography with dual electrochemical detection for the determination of serotonin and 5-hydroxyindoleacetic acid in rat brain dialysates.

Y. Michotte, G. Ebinger, S. Sarre, 1992, Journal of chromatography.

Effects of dietary sucrose on hippocampal serotonin release: a microdialysis study in the freely-moving rat

Y. Michotte, I. Smolders, G. Ebinger, 2001, British Journal of Nutrition.

NMDA‐mediated release of glutamate and GABA in the subthalamic nucleus is mediated by dopamine: an in vivo microdialysis study in rats

Y. Michotte, A. Massie, G. Ebinger, 2007, Journal of neurochemistry.

In vivo characterization of somatodendritic dopamine release in the substantia nigra of 6‐hydroxydopamine‐lesioned rats

Y. Michotte, G. Ebinger, S. Sarre, 2004, Journal of neurochemistry.

Absence of system xc- in mice decreases anxiety and depressive-like behavior without affecting sensorimotor function or spatial vision

L. Arckens, Y. Michotte, I. Smolders, 2015, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Neuroprotective effect of N‐acetyl‐aspartyl‐glutamate in combination with mild hypothermia in the endothelin‐1 rat model of focal cerebral ischaemia

Y. Michotte, G. Ebinger, S. Hachimi-Idrissi, 2005, Journal of neurochemistry.

Rat strain differences in peripheral and central serotonin transporter protein expression and function

Y. Michotte, J. Launay, M. Moisan, 2003, The European journal of neuroscience.

Serial Semiquantitative Imaging of Brain Damage Using Micro-SPECT and Micro-CT After Endothelin-1–Induced Transient Focal Cerebral Ischemia in Rats

Sophie Sarre, Tony Lahoutte, Vicky Caveliers, 2011, The Journal of Nuclear Medicine.

Mild hypothermia attenuates the excitatory amino acids overflow and diminishes the nitric oxide synthase activity during reperfusion after asphyxial cardiac arrest in rats.

Y. Michotte, S. Hachimi-Idrissi, L. Huyghens, 2014 .

Angiotensin IV and LVV-haemorphin 7 enhance spatial working memory in rats: Effects on hippocampal glucose levels and blood flow

Y. Michotte, I. Smolders, A. Albiston, 2009, Neurobiology of Learning and Memory.

Distribution of monoamines in human brain: evidence for neurochemical heterogeneity in subcortical as well as in cortical areas

Y. Michotte, G. Ebinger, P. Herregodts, 1991, Brain Research.

In vivo modulation of extracellular hippocampal glutamate and GABA levels and limbic seizures by group I and II metabotropic glutamate receptor ligands

Y. Michotte, A. Meurs, M. O'Neill, 2004, Journal of neurochemistry.

The effect of low-temperature ashing on the structure and composition of mineral components.

D. Massart, Y. Michotte, J. Pelsmaekers, 1976, Talanta.

Angiotensin AT4 receptor ligand interaction with cystinyl aminopeptidase and aminopeptidase N: [125I]Angiotensin IV only binds to the cystinyl aminopeptidase apo-enzyme.

Minh Tam Le, Patrick Vanderheyden, Yvette Michotte, 2006, European journal of pharmacology.

Effect of trihexyphenidyl, a non-selective antimuscarinic drug, on decarboxylation of L-dopa in hemi-Parkinson rats.

Y. Michotte, G. Ebinger, S. Sarre, 1998, European journal of pharmacology.

Metal ion modulation of cystinyl aminopeptidase.

Y. Michotte, V. Kersemans, G. Vauquelin, 2005, The Biochemical journal.

Multifactor simultaneous statistical optimization of the mobile phase composition for the separation of inorganic anions in reversed-phase ion-interaction chromatography

Y. Michotte, W. Baeyens, Q. Xianren, 1989 .

vGLUT2 heterozygous mice show more susceptibility to clonic seizures induced by pentylenetetrazol

Y. Michotte, W. Drinkenburg, D. Moechars, 2009, Neurochemistry International.

2-Chloro-N 6-cyclopentyladenosine-elicited attenuation of evoked glutamate release is not sufficient to give complete protection against pilocarpine-induced seizures in rats

Y. Michotte, I. Smolders, G. Ebinger, 2001, Neuropharmacology.

Post‐ischaemic mild hypothermia inhibits apoptosis in the penumbral region by reducing neuronal nitric oxide synthase activity and thereby preventing endothelin‐1‐induced hydroxyl radical formation

Y. Michotte, G. Ebinger, S. Hachimi-Idrissi, 2005, The European journal of neuroscience.

Effect of resuscitative mild hypothermia on glutamate and dopamine release, apoptosis and ischaemic brain damage in the endothelin‐1 rat model for focal cerebral ischaemia

Y. Michotte, G. Ebinger, S. Hachimi-Idrissi, 2003, Journal of neurochemistry.

Biphasic and bilateral changes in striatal VGLUT1 and 2 protein expression in hemi-Parkinson rats

L. Arckens, Y. Michotte, A. Massie, 2010, Neurochemistry International.

System Journal of Renin-angiotensin-aldosterone Journal of Renin-angiotensin-aldosterone System the Role of the Central Renin-angiotensin System in Parkinson's Disease Journal of Renin-angiotensin-aldosterone System Additional Services and Information For

Y. Michotte, P. Vanderheyden, S. Sarre, 2022 .

Impact of efflux transporters and of seizures on the pharmacokinetics of oxcarbazepine metabolite in the rat brain

Y. Michotte, M. Danhof, R. Voskuyl, 2008, British journal of pharmacology.

The neuroprotective action of candesartan is related to interference with the early stages of 6‐hydroxydopamine‐induced dopaminergic cell death

Y. Michotte, S. Sarre, B. Mertens, 2011, The European journal of neuroscience.

Robots in flexible analysis systems

P. Kool, Y. Michotte, Y. Michotte, 1985 .

The neuroprotective effect of post ischemic brief mild hypothermic treatment correlates with apoptosis, but not with gliosis in endothelin-1 treated rats

Y. Michotte, S. Hachimi-Idrissi, R. Kooijman, 2012, BMC Neuroscience.

Improved sensitivity of the nano ultra-high performance liquid chromatography-tandem mass spectrometric analysis of low-concentrated neuropeptides by reducing aspecific adsorption and optimizing the injection solvent.

Erin E. Chambers, Y. Michotte, Y. Vander Heyden, 2014, Journal of chromatography. A.

An ultrasensitive nano UHPLC-ESI-MS/MS method for the quantification of three neuromedin-like peptides in microdialysates.

Erin E. Chambers, Y. Michotte, K. Maes, 2015, Bioanalysis.

Dopaminergic Control of the Neurotransmitter Release in the Subthalamic Nucleus: Implications for Parkinson’s Disease Treatment Strategies

Y. Michotte, S. Sarre, Anissa El Arfani, 2011 .