S. Mathieu

发表

Development of Orally Efficacious Allosteric Inhibitors of TNFα via Fragment-Based Drug Design.

S. C. Panchal, Philip B. Cox, P. Hajduk, 2020, Journal of medicinal chemistry.

NRF2 activator A-1396076 ameliorates inflammation in autoimmune disease models by inhibiting antigen dependent T cell activation

Christian Goess, P. Richardson, D. Donnelly-roberts, 2020, Journal of translational autoimmunity.

DipeptidaseAminodipeptidase, Quiescent Cell Proline of a Novel Post-Proline-Cleaving Vesicular Localization and Characterization

S. Mathieu, B. Huber, M. Chiravuri, 2000 .

Vesicular Localization and Characterization of a Novel Post-Proline-Cleaving Aminodipeptidase, Quiescent Cell Proline Dipeptidase1

S. Mathieu, B. Huber, M. Chiravuri, 2000, The Journal of Immunology.

Discovery of ABBV-3373, an Anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody Drug Conjugate.

Christian Goess, A. Hobson, S. Mathieu, 2022, Journal of medicinal chemistry.

POS0365 ANTI-TNF GLUCOCORTICOID RECEPTOR MODULATOR ANTIBODY DRUG CONJUGATE FOR THE TREATMENT OF AUTOIMMUNE DISEASES

Christian Goess, S. Mathieu, M. Ruzek, 2021 .

The Bcl-2 Family Antagonist ABT-737 Significantly Inhibits Multiple Animal Models of Autoimmunity

Christian Goess, S. Mathieu, S. Rosenberg, 2009, The Journal of Immunology.

ABBV-105, a selective and irreversible inhibitor of Bruton’s tyrosine kinase, is efficacious in multiple preclinical models of inflammation

Christian Goess, S. Mathieu, E. Sampson, 2018, Modern rheumatology.

Role of α7 nicotinic acetylcholine receptors in regulating tumor necrosis factor-α (TNF-α) as revealed by subtype selective agonists

J. Waring, S. Mathieu, Jinhe Li, 2009, Journal of Neuroimmunology.

Design and Development of Glucocorticoid Receptor Modulators as Immunology Antibody-Drug Conjugate Payloads.

A. Hobson, S. Mathieu, R. Stoffel, 2022, Journal of medicinal chemistry.

Optimization of Drug-Linker to Enable Long-term Storage of Antibody-Drug Conjugate for Subcutaneous Dosing.

A. Hobson, S. Mathieu, M. McPherson, 2023, Journal of medicinal chemistry.

Homodimerization via a leucine zipper motif is required for enzymatic activity of quiescent cell proline dipeptidase.

S. Mathieu, H. Lee, B. Huber, 2000, The Journal of biological chemistry.

An anti–TNF–glucocorticoid receptor modulator antibody-drug conjugate is efficacious against immune-mediated inflammatory diseases

K. Longenecker, A. Hobson, S. Mathieu, 2024, Science Translational Medicine.