J. Yokota

B. Morris, J. Yokota, T. Kohno, 1999, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Rapid assessment of two major repair activities against DNA double-strand breaks in vertebrate cells.

David J. Chen, J. Yokota, T. Kohno, 2006, Biochemical and biophysical research communications.

Allelic imbalance on chromosome 18 in neuroblastoma.

J. Yokota, R. Hanada, J. Takita, 2000, European journal of cancer.

p53 mutations in human lung tumors.

J. Yokota, K. Kok, K. Simon, 1992, Cancer research.

A novel splice-site variant of the base excision repair gene MYH is associated with production of an aberrant mRNA transcript encoding a truncated MYH protein not localized in the nucleus.

J. Yokota, S. Tsugane, H. Sugimura, 2004, Carcinogenesis.

Suppressive activities of OGG1 and MYH proteins against G:C to T:A mutations caused by 8-hydroxyguanine but not by benzo[a]pyrene diol epoxide in human cells in vivo.

J. Yokota, T. Kohno, N. Sunaga, 2003, Carcinogenesis.

First case of aplastic anemia in a Japanese child with a homozygous missense mutation in the NBS1 gene (I171V) associated with genomic instability

J. Yokota, H. Shimada, S. Mimaki, 2004, Human Genetics.

Mutation analysis of coding sequences of the entire transforming growth factor beta type II receptor gene in sporadic human colon cancer using genomic DNA and Intron primers

J. Yokota, C. Harris, W. Bennett, 1997, Oncogene.

Mutation analysis of the Smad2 gene in human colon cancers using genomic DNA and intron primers.

J. Yokota, C. Harris, W. Bennett, 1998, Carcinogenesis.

Genetic alterations and expression of the protein phosphatase 1 genes in human cancers.

A. Okamoto, J. Yokota, T. Kohno, 2001, International journal of oncology.

Activation of the AKT and STAT3 pathways and prolonged survival by a mutant EGFR in human lung cancer cells.

J. Yokota, S. Matsumoto, H. Akça, 2006, Lung cancer.

ISOTOPE: ISOform-guided prediction of epiTOPEs in cancer

E. Eyras, J. Yokota, F. Sanz, 2020, bioRxiv.

Infrequent mutations of the transforming growth factor beta-type II receptor gene at chromosome 3p22 in human lung cancers with chromosome 3p deletions.

J. Yokota, C. Harris, T. Kohno, 1997, Carcinogenesis.

Orthotopic growth and metastasis of human non-small cell lung carcinoma cell injected into the pleural cavity of nude mice.

J. Yokota, H. Tsuda, Y. Niitsu, 1998, Cancer letters.

Loss of Keap 1 Function Activates Nrf 2 and Provides Advantages for Lung Cancer Cell Growth

S. Hirohashi, J. Yokota, T. Shibata, 2008 .

Reduced expression of MYO18B, a candidate tumor‐suppressor gene on chromosome arm 22q, in ovarian cancer

N. Yanaihara, A. Okamoto, J. Yokota, 2004, International journal of cancer.

OCIA domain containing 2 is highly expressed in adenocarcinoma mixed subtype with bronchioloalveolar carcinoma component and is associated with better prognosis

J. Yokota, M. Noguchi, T. Iijima, 2007, Cancer science.

Suicidal gene therapy for pleural metastasis of lung cancer by liposome-mediated transfer of herpes simplex virus thymidine kinase gene

J. Yokota, Teruhiko Yoshida, K. Shimizu, 1999, Cancer Gene Therapy.

Overexpression of candidate tumor suppressor gene FUS1 isolated from the 3p21.3 homozygous deletion region leads to G1 arrest and growth inhibition of lung cancer cells

J. Minna, J. Yokota, J. Roth, 2001, Oncogene.

Identification and characterization of families with aggregation of lung cancer.

J. Yokota, T. Kohno, Y. Tomizawa, 1998, Japanese journal of clinical oncology.

Increased formation of oxidative DNA damage, 8-hydroxydeoxyguanosine, in human livers with chronic hepatitis.

S. Hirohashi, J. Yokota, M. Sakamoto, 1994, Cancer research.

Genetic alterations of the c-erbB-2 oncogene occur frequently in tubular adenocarcinoma of the stomach and are often accompanied by amplification of the v-erbA homologue.

N. Nomura, J. Yokota, Teruhiko Yoshida, 1988, Oncogene.

Differential expression of the LAMB3 and LAMC2 genes between small cell and non-small cell lung carcinomas.

J. Yokota, T. Kohno, T. Niki, 2000, Biochemical and biophysical research communications.

DNA damage-inducible gene p33ING2 negatively regulates cell proliferation through acetylation of p53

X. Wang, J. Yokota, S. Linke, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Correlation between the status of the p53 gene and survival in patients with stage I non-small cell lung carcinoma

S. Hirohashi, J. Yokota, T. Kohno, 1999, Oncogene.

Variable mutations of the RB gene in small-cell lung carcinoma.

A. Okamoto, J. Yokota, T. Akiyama, 1990, Oncogene.

Growth suppression by MYC inhibition in small cell lung cancer cells with TP53 and RB1 inactivation

J. Yokota, T. Kohno, M. Perucho, 2016, Oncotarget.

Association of KRAS polymorphisms with risk for lung adenocarcinoma accompanied by atypical adenomatous hyperplasias.

Kenji Suzuki, J. Yokota, T. Kohno, 2008, Carcinogenesis.

Frequent allelic losses on chromosomes 2q, 18q, and 22q in advanced non-small cell lung carcinoma.

J. Yokota, T. Kohno, M. Shiseki, 1994, Cancer research.

Clinicopathological significance of Fhit protein expression in stage I non-small cell lung carcinoma.

J. Yokota, T. Kohno, Y. Tomizawa, 1998, Cancer research.

Clinicopathological significance of epigenetic inactivation of RASSF1A at 3p21.3 in stage I lung adenocarcinoma.

J. Minna, Tesshi Yamada, J. Yokota, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Frequent Alleile Losses and Mutations of the p53 Gene in Human Ovarian Cancer1

A. Okamoto, J. Yokota, T. Sugimura, 2006 .

Familial gastric cancer: clinicopathological characteristics, RER phenotype and germline p53 and E-cadherin mutations.

J. Yokota, T. Kohno, A. Reeve, 1999, Carcinogenesis.

Multiple genetic alterations in human carcinogenesis.

S. Hirohashi, J. Yokota, T. Sugimura, 1992, Environmental health perspectives.

Activation of N-ras gene in a rat hepatocellular carcinoma induced by dibutylnitrosamine and butylated hydroxytoluene.

J. Yokota, T. Sugimura, H. Sakamoto, 1987, Japanese journal of cancer research : Gann.

Mutation and expression of the DCC gene in human lung cancer.

J. Yokota, T. Kohno, K. Inoue, 2000, Neoplasia.

Alterations of the tumour suppressor gene DCC in neuroblastoma.

J. Yokota, R. Hanada, J. Takita, 1997, European journal of cancer.

Breakpoint junction of interstitial homozygous deletion at chromosome 2q33 in a small cell lung carcinoma.

J. Yokota, T. Kohno, J. Inazawa, 1996, DNA research : an international journal for rapid publication of reports on genes and genomes.

Absence of Germline CHK2 Mutations in Familial Gastric Cancer

J. Yokota, H. Katai, K. Yoshimura, 2000, Japanese journal of cancer research : Gann.

Allelotype and replication error phenotype of small cell lung carcinoma.

S. Hirohashi, J. Yokota, T. Kohno, 1997, Carcinogenesis.

Alternative splicing of the neurofibromatosis 1 gene correlates with growth patterns and neuroendocrine properties of human small‐cell lung‐carcinoma cells

J. Yokota, K. Ookawa, H. Haga, 1995, International journal of cancer.

Comprehensive genomic profiles of small cell lung cancer

Martin Vingron, Jan O. Korbel, Lucia Anna Muscarella, 2015, Nature.

Familial gastric cancer: overview and guidelines for management*

J. Yokota, C. Caldas, D. Huntsman, 1999, Journal of medical genetics.

Pipeline design to identify key features in prognosis biomarker analysis using a real lung cancer dataset

J. Yokota, I. Galván-Femenía, R. Cid, 2017 .

Adult T‐cell leukemia: Structures and expression of the p53 gene

J. Yokota, K. Yamato, Y. Sameshima, 1991, International journal of cancer.

Targeted Disruption of Ing2 Results in Defective Spermatogenesis and Development of Soft-Tissue Sarcomas

K. Kumamoto, J. Yokota, C. Harris, 2010, PloS one.

Whole genome comparison of allelic imbalance between noninvasive and invasive small-sized lung adenocarcinomas.

Shingo Matsumoto, Eiji Shimizu, Koji Tsuta, 2009, Cancer research.

CYP1A1, GSTM1, and GSTT1 Polymorphisms, Smoking, and Lung Cancer Risk in a Pooled Analysis among Asian Populations

J. Yokota, L. Le Marchand, P. Pisani, 2008, Cancer Epidemiology Biomarkers & Prevention.

Glutathione-S-transferase pi as a determinant of drug resistance in transfectant cell lines.

J. Yokota, N. Saijo, K. Tew, 1990, The Journal of biological chemistry.

T-cell leukemia/lymphoma Down-regulation of TCF8 is involved in the leukemogenesis of adult

J. Yokota, T. Kohno, T. Taki, 2013 .

Infrequent mutations of the activating transcription factor-2 gene in human lung cancer, neuroblastoma and breast cancer.

J. Yokota, T. Kohno, S. Ishii, 2002, International journal of oncology.

Inactivation of p16 in Hepatocellular Carcinoma

J. Yokota, Y. Kanai, M. Sakamoto, 1998 .

Detection of Three Genetic Polymorphisms in the 5′‐Flanking Region and Intron 1 of Human CYP1A2 in the Japanese Population

J. Yokota, T. Kamataki, T. Yokoi, 1999, Japanese journal of cancer research : Gann.

Poly(ADP-ribose) polymerase-1 gene in human tumor cell lines: Its expression and structural alteration

Tesshi Yamada, S. Hirohashi, J. Yokota, 2004, Proceedings of the Japan Academy. Series B, Physical and Biological Sciences.

Isolation of an Amplified DNA Sequence in Stomach Cancer

J. Yokota, Teruhiko Yoshida, T. Sugimura, 1990, Japanese journal of cancer research : Gann.

Two homologous oncogenes, HST1 and INT2, are closely located in human genome.

J. Yokota, P. Little, T. Sugimura, 1988, Biochemical and biophysical research communications.

Human HST1 (HSTF1) gene maps to chromosome band 11q13 and coamplifies with the INT2 gene in human cancer.

J. Yokota, H. Satoh, K. Miyagawa, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Deficiency of Myo18B in mice results in embryonic lethality with cardiac myofibrillar aberrations

J. Yokota, A. Otsuka, T. Kohno, 2008, Genes to cells : devoted to molecular & cellular mechanisms.

Formation of an oxidative DNA damage, 8-hydroxydeoxyguanosine, in mouse lung DNA after intratracheal instillation of diesel exhaust particles and effects of high dietary fat and beta-carotene on this process.

J. Yokota, Y. Nagamachi, H. Kasai, 1995, Carcinogenesis.

Frequent allelic losses and mutations of the p53 gene in human ovarian cancer.

A. Okamoto, J. Yokota, T. Sugimura, 1991, Cancer research.

OGG1 protein suppresses G:C-->T:A mutation in a shuttle vector containing 8-hydroxyguanine in human cells.

J. Yokota, T. Kohno, N. Sunaga, 2001, Carcinogenesis.

Relation between Nucleolar Size and Growth Characteristics in Small Cell Lung Cancer Cell Lines

A. Okamoto, J. Yokota, Y. Shimosato, 1991, Japanese journal of cancer research : Gann.

Selection of Radioresistant Cells by Vitamin A Deficiency in a Small Cell Lung Cancer Cell Line

J. Yokota, Y. Shimosato, M. Terada, 1990, Japanese journal of cancer research : Gann.

Absence of hSNF5/INI1 mutation in human lung cancer.

J. Yokota, T. Kohno, H. Kuwano, 2000, Cancer letters.

Identification of genes differentially expressed in association with metastatic potential of K-1735 murine melanoma by messenger RNA differential display.

J. Yokota, N. Shindo-Okada, Y. Hashimoto, 1996, Cancer research.

Identification of a breakpoint cluster region 3' of the ribophorin I gene at 3q21 associated with the transcriptional activation of the EVI1 gene in acute myelogenous leukemias with inv(3)(q21q26).

J. Yokota, N. Kamada, S. Takahashi, 1994, Blood.

In vitro growth suppression and morphological change in a human renal cell carcinoma cell line by the introduction of normal chromosome 3 via microcell fusion

M. Oshimura, J. Yokota, M. Yoshida, 1994, Molecular carcinogenesis.

Concordant deletions of chromosome 3p and loss of heterozygosity for chromosomes 13 and 17 in small cell lung carcinoma.

M. Oshimura, J. Yokota, M. Noguchi, 1989, Cancer research.

p53 Mutations in Human Lung Tumors1

Carl W. Miller, J. Yokota, K. Kok, 2006 .

p 53 Mutations in Human Lung Tumors 1

Carl W. Miller, J. Yokota, K. Kok, 2006 .

Evidence for a putative telomerase repressor gene in the 3p14.2–p21.1 region

M. Oshimura, J. Yokota, J. Barrett, 1998, Genes, chromosomes & cancer.

Loss of heterozygosity on the short arm of chromosome 3 in carcinoma of the uterine cervix.

J. Yokota, T. Nakajima, T. Sugimura, 1989, Cancer research.

Dicer is essential for the survival and proliferation of retinal progenitor cells

T. Higuchi, S. Miyano, J. Yokota, 2022 .

Suppression of chemically induced and spontaneously occurring oxidative mutagenesis by three alleles of human OGG1 gene encoding 8-hydroxyguanine DNA glycosylase.

J. Yokota, T. Kohno, M. Yamada, 2004, Mutation research.

Somatic mutations and single nucleotide polymorphisms of base excision repair genes involved in the repair of 8-hydroxyguanine in damaged DNA.

J. Yokota, T. Kohno, S. Yamaguchi, 2001, Cancer letters.

Reconstitution of the RB gene suppresses the growth of small-cell lung carcinoma cells carrying multiple genetic alterations.

J. Yokota, R. Takahashi, M. Shiseki, 1993, Oncogene.

Molecular footprints of human lung cancer progression

J. Yokota, T. Kohno, 2004, Cancer science.

Activation of RB tumor suppressor protein and growth suppression of small cell lung carcinoma cells by reintroduction of p16INK4A gene.

J. Yokota, E. Shimizu, S. Sone, 1999, International journal of oncology.

Growth suppression of non-small cell lung carcinoma cells by the introduction of the p16(INK4A) gene.

J. Yokota, T. Kohno, T. Akiyama, 1997, International journal of oncology.

Mutations of the p53 gene in myelodysplastic syndrome and overt leukemia.

J. Yokota, K. Oshimi, H. Mizoguchi, 1995, Leukemia research.

Molecular analysis of the adenomatous polyposis coli gene in sarcomas, hematological malignancies and noncolonic, neoplastic tissues

J. Yokota, C. Miller, H. Mizoguchi, 1997, Journal of Molecular Medicine.

Frequent Loss of Heterozygosity on Chromosomes 16 and 4 in Human Hepatocellular Carcinoma

S. Hirohashi, J. Yokota, H. Tsuda, 1990, Japanese journal of cancer research : Gann.

LEVELS OF GLUTATHIONES TRANSFERASE π mRNA IN HUMAN LUNG CANCER CELL LINES CORRELATE WITH THE RESISTANCE TO CISPLATIN AND CARBOPLATIN

J. Yokota, N. Saijo, Y. Fujiwara, 1988, Japanese journal of cancer research : Gann.

Ovarian Cancer: Loss of Heterozygosity Frequently Occurs in the ATM Gene, but Structural Alterations Do Not Occur in This Gene

J. Yokota, H. Koeffler, N. Tsuruoka, 1999, Oncology.

Mutations of the p53 tumour suppressor gene in haematologic neoplasms

J. Yokota, K. Oshimi, H. Mizoguchi, 1992, British journal of haematology.

Events on different chromosomes alter the genes for the two peptides of platelet-derived growth factor in an osteogenic sarcoma.

J. Yokota, H. Battifora, M. Cline, 1987, Cancer genetics and cytogenetics.

RER phenotype and its associated mutations in familial gastric cancer.

J. Yokota, H. Sugimura, K. Shinmura, 1998, Carcinogenesis.

EVI-1 zinc finger protein works as a transcriptional activator via binding to a consensus sequence of GACAAGATAAGATAAN1-28 CTCATCTTC.

J. Yokota, T. Taki, J. Ihle, 1995, Oncogene.

Frequent loss of heterozygosity on chromosome 14q in neuroblastoma.

J. Yokota, T. Sugimura, H. Mugishima, 1989, Cancer research.

An atypical case of megakaryoblastic leukaemia.

J. Yokota, S. Asano, K. Morishita, 2009, Scandinavian journal of haematology.

E‐cadherin gene variants in gastric cancer families whose probands are diagnosed with diffuse gastric cancer

J. Yokota, T. Nakajima, H. Katai, 2002, International journal of cancer.

Report on the first meeting of the International Collaborative Group on Hereditary Gastric Cancer.

J. Yokota, C. Caldas, J. G. Park, 2000, Journal of the National Cancer Institute.

hOGG1 exon7 polymorphism and gastric cancer in case-control studies of Japanese Brazilians and non-Japanese Brazilians.

J. Yokota, S. Tsugane, I. Nishimoto, 2001, Cancer letters.

HOMER2 binds MYO18B and enhances its activity to suppress anchorage independent growth.

J. Yokota, K. Sutoh, M. Maeda, 2007, Biochemical and biophysical research communications.

Newly Established Uterine Cervical Carcinoma Cell Line with Co‐amplification of Human Papillomavirus DNA and c‐myc Gene

S. Hirohashi, J. Yokota, T. Nakajima, 1991, Japanese journal of cancer research : Gann.

Chromosomal localization of putative tumor-suppressor genes in several human cancers.

J. Yokota, T. Sugimura, M. Terada, 1991, Environmental health perspectives.

Microsatellite instability in lymphoid leukemia and lymphoma cell lines but not in myeloid leukemia cell lines

J. Yokota, T. Kohno, T. Kodera, 1999, Genes, chromosomes & cancer.

Proto-oncogene abnormalities in human breast cancer: correlations with anatomic features and clinical course of disease.

J. Yokota, H. Battifora, M. Cline, 1987, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Deletion map of chromosome 9 and p16 (CDKN2A) gene alterations in neuroblastoma.

J. Yokota, T. Kohno, R. Hanada, 1997, Cancer research.

Alterations of polypeptide composition of mature granulocytes obtained from patients with chronic myelogenous leukemia.

J. Yokota, S. Asano, A. Iwamoto, 1982, Blood.

Somatic mutations and genetic polymorphisms of the PPP1R3 gene in patients with several types of cancers

A. Okamoto, J. Yokota, T. Kohno, 2000, Oncogene.

AMPLIFICATION OF c-erbB-2 ONCOGENE IN HUMAN ADENOCARCINOMAS IN VIVO

J. Yokota, T. Sugimura, M. Terada, 1986, The Lancet.

Infrequent loss of chromosomal heterozygosity in human stomach cancer.

J. Yokota, T. Sugimura, H. Mizoguchi, 1988, Cancer research.

Introduction of normal chromosome 3p modulates the tumorigenicity of a human renal cell carcinoma cell line YCR.

M. Oshimura, J. Yokota, T. Shuin, 1990, Oncogene.

MYO18B interacts with the proteasomal subunit Sug1 and is degraded by the ubiquitin-proteasome pathway.

J. Yokota, K. Sutoh, T. Kon, 2006, Biochemical and biophysical research communications.

Homozygous deletion and frequent allelic loss of the 21q11.1‐q21.1 region including the ANA gene in human lung carcinoma

J. Yokota, T. Kohno, M. Ohki, 1998, Genes, chromosomes & cancer.

Alterations of the p53 gene are common and critical events for the maintenance of malignant phenotypes in small-cell lung carcinoma.

S. Hirohashi, J. Yokota, T. Sugimura, 1992, Oncogene.

Point mutation of the p53 gene resulting in splicing inhibition in small cell lung carcinoma.

J. Yokota, T. Akiyama, T. Sugimura, 1990, Biochemical and biophysical research communications.

Multiple genetic alterations in small-cell lung carcinoma.

J. Yokota, T. Akiyama, T. Sugimura, 1989, Princess Takamatsu symposia.

Identification of a novel phospholipase C family gene at chromosome 2q33 that is homozygously deleted in human small cell lung carcinoma.

J. Yokota, T. Kohno, T. Yamamoto, 1995, Human molecular genetics.

Frequent expression of receptors for granulocyte‐macrophage colony‐stimulating factor on human nonhematopoietic tumor cell lines

J. Yokota, K. Miyazono, K. Miyagawa, 1990, Journal of cellular physiology.

Corrigendum to: Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines Leukemia Research 24 (2000), 255-262.

J. Yokota, T. Kohno, Y. Hayashi, 2001, Leukemia research.

8-hydroxyguanine (7,8-dihydro-8-oxoguanine) DNA glycosylase and AP lyase activities of hOGG1 protein and their substrate specificity.

J. Yokota, H. Sugimura, K. Shinmura, 1997, Mutation research.

Fusion of the MLL gene with two different genes, AF-6 and AF-5alpha, by a complex translocation involving chromosomes 5, 6, 8 and 11 in infant leukemia.

J. Yokota, M. Seto, Y. Hayashi, 1996, Oncogene.

Alleile Loss on Chromosome 17 p and / > 53 Mutations in Human Endometrial Carcinoma of the Uterus 1

A. Okamoto, J. Yokota, Y. Sameshima, 2006 .

Gene Amplification-Associated Overexpression of the Selenoprotein tRNA Enzyme TRIT1 Confers Sensitivity to Arsenic Trioxide in Small-Cell Lung Cancer

F. Setién, M. Esteller, J. Yokota, 2021, Cancers.

Evaluation of CYP2A6 genetic polymorphisms as determinants of smoking behavior and tobacco-related lung cancer risk in male Japanese smokers.

J. Yokota, H. Yamazaki, H. Dosaka-akita, 2004, Carcinogenesis.

Genetic polymorphism of CYP2A6 gene and tobacco-induced lung cancer risk in male smokers.

Jun Yokota, J. Yokota, H. Dosaka-akita, 2002, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Identification of a functional SNP in the 3'UTR of CXCR2 that is associated with reduced risk of lung cancer.

Jun Yokota, Takashi Kohno, E. Bowman, 2015, Cancer research.

Alteration of polypeptide synthesis and composition during differentiation of human leukemia cell line HL60.

J. Yokota, S. Asano, A. Iwamoto, 1984, Leukemia research.

Tyrosine phosphorylation of paxillin affects the metastatic potential of human osteosarcoma

Satoshi Inoue, Jun Yokota, Y. Ouchi, 2005, Oncogene.

Frequent co-localization of Cox-2 and laminin-5 gamma2 chain at the invasive front of early-stage lung adenocarcinomas.

Miyuki Saito, Setsuo Hirohashi, Jun Yokota, 2002, The American journal of pathology.

Correlation between long-term survival in breast cancer patients and amplification of two putative oncogene-coamplification units: hst-1/int-2 and c-erbB-2/ear-1.

S. Hirohashi, J. Yokota, H. Tsuda, 1989, Cancer research.

Cancer Susceptibility Polymorphism of p53 at Codon 72 Affects Phosphorylation and Degradation of p53 Protein*

J. Yokota, T. Kohno, T. Shibata, 2011, The Journal of Biological Chemistry.

Frequent loss of heterozygosity in the region of the D7S523 locus in advanced ovarian cancer

Carl W. Miller, J. Yokota, N. Tsuruoka, 1997, Genes, chromosomes & cancer.

Retrospective study on amplification of N-myc and c-myc genes in pediatric solid tumors and its association with prognosis and tumor differentiation.

S. Hirohashi, J. Yokota, H. Tsuda, 1988, Laboratory investigation; a journal of technical methods and pathology.

Expression and clinical significance of genes frequently mutated in small cell lung cancers defined by whole exome/RNA sequencing.

S. Miyano, J. Yokota, C. Harris, 2015, Carcinogenesis.

Isolation of a novel Sry-related gene that is expressed in high-metastatic K-1735 murine melanoma cells.

J. Yokota, S. Takenoshita, Y. Nagamachi, 1997, Genomics.

Druggable Oncogene Fusions in Invasive Mucinous Lung Adenocarcinoma

Koji Tsuta, Shun-ichi Watanabe, Yoko Shimada, 2014, Clinical Cancer Research.

Unbalanced translocation, a major chromosome alteration causing loss of heterozygosity in human lung cancer

J. Yokota, H. Ogiwara, T. Kohno, 2008, Oncogene.

Frequent chromosome 8q gains in human small cell lung carcinoma detected by arbitrarily primed-PCR genomic fingerprinting.

J. Yokota, T. Kohno, M. Perucho, 2000, Cancer genetics and cytogenetics.

How many tumor suppressor genes are involved in human lung carcinogenesis?

J. Yokota, T. Kohno, 1999, Carcinogenesis.

Induction of apoptosis but not G1 arrest by expression of the wild-type p53 gene in small cell lung carcinoma.

J. Yokota, T. Okazaki, S. Tsuchida, 1996, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Microsatellite instability in primary and metastatic lung carcinomas

S. Hirohashi, J. Yokota, T. Okazaki, 1995, Genes, chromosomes & cancer.

Loss of heterozygosity on chromosomes 3, 13, and 17 in small-cell carcinoma and on chromosome 3 in adenocarcinoma of the lung.

M Terada, J. Yokota, T. Sugimura, 1987, Proceedings of the National Academy of Sciences of the United States of America.

p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity.

Koh Miura, Jun Yokota, Ettore Appella, 2003, Cancer research.

A catalog of genes homozygously deleted in human lung cancer and the candidacy of PTPRD as a tumor suppressor gene

Luc Girard, Jun Yokota, Takashi Kohno, 2010, Genes, chromosomes & cancer.

MYCL is a target of a BET bromodomain inhibitor, JQ1, on growth suppression efficacy in small cell lung cancer cells

Andreu Alibés, Jun Yokota, Takashi Kohno, 2016, Oncotarget.

Allele loss on chromosome 16 associated with progression of human hepatocellular carcinoma.

S. Hirohashi, J. Yokota, H. Tsuda, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Optimal Targeting of HER 2 – PI 3 K Signaling in Breast Cancer : Mechanistic Insights and Clinical Implications

A. Schetter, S. Groshen, E. Bowman, 2013 .

The SRY-HMG box gene, SOX4, is a target of gene amplification at chromosome 6p in lung cancer.

J. Cigudosa, J. Benítez, J. Yokota, 2009, Human molecular genetics.

Expression of the Elm1 Gene, a Novel Gene of the CCN (Connective Tissue Growth Factor, Cyr61/Cef10, and Neuroblastoma Overexpressed Gene) Family, Suppresses In Vivo Tumor Growth and Metastasis of K-1735 Murine Melanoma Cells

J. Yokota, N. Shindo-Okada, T. Shiroishi, 1998, The Journal of experimental medicine.

A Three-microRNA Signature Predicts Responses to Platinum-Based Doublet Chemotherapy in Patients with Lung Adenocarcinoma

A. Schetter, K. Kumamoto, J. Yokota, 2014, Clinical Cancer Research.

Disappearance of the angiogenic potential of endothelial cells caused by Argonaute2 knockdown.

Tomohiro Asai, Naoto Oku, J. Yokota, 2008, Biochemical and biophysical research communications.

A gene‐alteration profile of human lung cancer cell lines

Jun Yokota, Ruben Pio, Takashi Kohno, 2009, Human mutation.

Advances in Brief Mutations in the p 16 @ ' @ 4 / MTS 1 / CDKN 2 , p 15 @ 4 B / MTS 2 , and p 18 Genes in Primary and Metastatic Lung Cancer '

G. Hannon, A. Okamoto, J. Yokota, 2006 .

Prognostic significance of allelic imbalances on chromosome 9p in stage I non-small cell lung carcinoma.

S. Hirohashi, J. Yokota, T. Kohno, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

p16INK4 Expression Is Associated with the Increased Sensitivity of Human Non‐small Cell Lung Cancer Cells to DNA Topoisomerase I Inhibitors

J. Yokota, N. Saijo, H. Yokote, 1997, Japanese journal of cancer research : Gann.

Erratum: Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis

F. Setién, M. Esteller, J. Yokota, 2016, Oncogene.

Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis

F. Setién, M. Esteller, J. Yokota, 2015, Oncogene.

The Expression of Four Genes as a Prognostic Classifier for Stage I Lung Adenocarcinoma in 12 Independent Cohorts

Jun Yokota, Takashi Kohno, Seiichi Takenoshita, 2014, Cancer Epidemiology, Biomarkers & Prevention.

Gene aberrations for precision medicine against lung adenocarcinoma

J. Yokota, T. Kohno, S. Takenoshita, 2016, Cancer science.

Frequent BRG1/SMARCA4–inactivating mutations in human lung cancer cell lines

Jun Yokota, Ruben Pio, Takashi Kohno, 2008, Human mutation.

Genomic Profiling of Patient-Derived Xenografts for Lung Cancer Identifies B2M Inactivation Impairing Immunorecognition.

J. Yokota, D. Pisano, E. Felip, 2017, Clinical cancer research : an official journal of the American Association for Cancer Research.

Genomic Profiling of Patient-Derived Xenografts for Lung Cancer Identifies B2M Inactivation Impairing Immunorecognition

J. Yokota, D. Pisano, E. Felip, 2017, Clinical Cancer Research.

Possible involvement of LKB1-AMPK signaling in non-homologous end joining

J. Yokota, C. Harris, H. Ogiwara, 2014, Oncogene.

MAX inactivation in small cell lung cancer disrupts MYC-SWI/SNF programs and is synthetic lethal with BRG1.

J. Yokota, T. Kohno, S. Moran, 2014, Cancer discovery.

A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1.

J. Yokota, H. Ogiwara, T. Kohno, 2013, Cancer research.

Inactivating mutations in SWI/SNF chromatin remodeling genes in human cancer.

J. Yokota, H. Ogiwara, T. Kohno, 2013, Japanese journal of clinical oncology.

Alterations in the INK4a/ARF locus and their effects on the growth of human osteosarcoma cell lines.

J. Yokota, K. Shimizu, M. Park, 2002, Cancer genetics and cytogenetics.

NuMA Is Required for the Selective Induction of p53 Target Genes

T. Nagase, J. Yokota, M. Miyazaki, 2013, Molecular and Cellular Biology.

Report of the Seventh International Symposium of the Foundation for Promotion of Cancer Research: fundamental and clinical research in lung cancer.

J. Yokota, A. Gazdar, N. Saijo, 1994, Japanese journal of clinical oncology.

Epidermal Growth Factor Receptor Tyrosine Kinase Defines Critical Prognostic Genes of Stage I Lung Adenocarcinoma

Masao Nagasaki, Satoru Miyano, Teppei Shimamura, 2012, PloS one.

Identification of genes upregulated in ALK-positive and EGFR/KRAS/ALK-negative lung adenocarcinomas.

Satoru Miyano, Rui Yamaguchi, Seiichiro Yamamoto, 2012, Cancer research.

Genomic Ampli fi cation of CD 274 ( PD-L 1 ) in Small-Cell Lung Cancer

I. Petersen, J. Yokota, C. Harris, 2017 .

Genomic Amplification of CD274 (PD-L1) in Small-Cell Lung Cancer

I. Petersen, J. Yokota, C. Harris, 2016, Clinical Cancer Research.

Genetic basis for susceptibility to lung cancer: Recent progress and future directions.

Jun Yokota, Takashi Kohno, J. Yokota, 2010, Advances in cancer research.

Clonal and Parallel Evolution of Primary Lung Cancers and Their Metastases Revealed by Molecular Dissection of Cancer Cells

J. Yokota, T. Kohno, Y. Arai, 2007, Clinical Cancer Research.

Genetic and epigenetic alterations of the candidate tumor‐suppressor gene MYO18B, on chromosome arm 22q, in colorectal cancer

J. Yokota, A. Otsuka, T. Kohno, 2005, Genes, chromosomes & cancer.

Genetic alterations responsible for metastatic phenotypes of lung cancer cells

J. Yokota, T. Kohno, M. Tani, 2004, Clinical & Experimental Metastasis.

Expression and mutational analysis of the DCC, DPC4, and MADR2/JV18-1 genes in neuroblastoma.

J. Yokota, R. Hanada, J. Takita, 1997, Cancer research.

Activation of EVI1 transcripts with chromosomal translocation joining the TCRVβ locus and the EVI1 gene in human acute undifferentiated leukemia cell line (Kasumi-3) with a complex translocation of der(3)t(3;7;8)

J. Yokota, N. Kamada, M. Taniwaki, 1999, Leukemia.

Molecular processes of chromosome 9p21 deletions causing inactivation of the p16 tumor suppressor gene in human cancer: deduction from structural analysis of breakpoints for deletions.

J. Yokota, T. Kohno, 2006, DNA repair.

Prevalent Involvement of Illegitimate V(D)J Recombination in Chromosome 9p21 Deletions in Lymphoid Leukemia*

Kaoru Inoue, Jun Yokota, Takashi Kohno, 2002, The Journal of Biological Chemistry.

The intracellular E-cadherin germline mutation V832 M lacks the ability to mediate cell–cell adhesion and to suppress invasion

J. Yokota, D. Huntsman, M. Mareel, 2003, Oncogene.

Down-regulation of TCF8 is involved in the leukemogenesis of adult T-cell leukemia/lymphoma.

J. Yokota, T. Kohno, T. Taki, 2008, Blood.

Alterations of the PPP1R3 gene in human cancer.

A. Okamoto, J. Yokota, Tadao Tanaka, 1999, Cancer Research.

Association of CDKN2A (p16)/CDKN2B (p15) alterations and homozygous chromosome arm 9p deletions in human lung carcinoma

J. Yokota, T. Kohno, S. Ohwada, 1998, Genes, chromosomes & cancer.

Genomic profiling in advanced stage non-small-cell lung cancer patients with platinum-based chemotherapy identifies germline variants with prognostic value in SMYD2.

Rafael de Cid, David Torrents, Lauro Sumoy, 2018, Cancer treatment and research communications.

Alterations of myc, myb, and rasHa proto-oncogenes in cancers are frequent and show clinical correlation.

J. Yokota, H. Battifora, Y. Tsunetsugu-Yokota, 1986, Science.

Oncogenes of stomach cancers.

J. Yokota, T. Sugimura, H. Sakamoto, 1990, Basic life sciences.

Probing the chromosome 9p21 region susceptible to DNA double-strand breaks in human cells in vivo by restriction enzyme transfer

J. Yokota, T. Kohno, Masanori Sato, 2005, Oncogene.

Pathogenetic and biologic significance of TP14ARF alterations in nonsmall cell lung carcinoma.

J. Yokota, T. Kohno, K. Shimizu, 2003, Cancer Genetics and Cytogenetics.

A novel tumor suppressor locus on chromosome 18q involved in the development of human lung cancer.

S. Hirohashi, J. Yokota, T. Kohno, 1998, Cancer research.

Loss of heterozygosity in neuroblastomas--an overview.

J. Yokota, J. Takita, Y. Hayashi, 1997, European journal of cancer.

Identification of chromosome arm 9p as the most frequent target of homozygous deletions in lung cancer

J. Minna, J. Yokota, T. Kohno, 2005, Genes, chromosomes & cancer.

Mutations and deletions of the CBP gene in human lung cancer.

Tokuki Sakiyama, Jun Yokota, Takashi Kohno, 2005, Clinical cancer research : an official journal of the American Association for Cancer Research.

Inactivation of the PTEN/MMAC1/TEP1 gene in human lung cancers

J. Yokota, T. Kohno, M. Takahashi, 1998, Genes, chromosomes & cancer.

Constitutive activation of the Wnt signaling pathway by CTNNB1 (β‐catenin) mutations in a subset of human lung adenocarcinoma

J. Yokota, T. Kohno, E. Fearon, 2001, Genes, chromosomes & cancer.

Identification of a 428-kb homozygously deleted region disrupting the SEZ6L gene at 22q12.1 in a lung cancer cell line

J. Yokota, T. Kohno, T. Niki, 2000, Oncogene.

Germline Mutations of the PTEN/MMAC1 Gene in Japanese Patients with Cowden Disease

J. Yokota, T. Kohno, T. Fukutomi, 1998, Japanese journal of cancer research : Gann.

Genetic defects in cancer cells and cancer prone families.

J. Yokota, T. Kohno, A. Sasaki, 1996, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation.

Mutation and expression of the p51 gene in human lung cancer.

J. Yokota, T. Kohno, C. Kawahara, 1999, Neoplasia.

chromosome 12p12.3-13.1 (region of TEL and Kip1 loci) and chromosome 12q23-ter: evidence for two new genes.

J. Yokota, H. Koeffler, S. Takeuchi, 2007 .

Ovarian cancer has frequent loss of heterozygosity at chromosome 12p12.3-13.1 (region of TEL and Kip1 loci) and chromosome 12q23-ter: evidence for two new tumour-suppressor genes.

J. Yokota, H. Koeffler, Y. Hatta, 1997, British Journal of Cancer.

Detection of novel germ-line p53 mutations in diverse-cancer-prone families identified by selecting patients with childhood adrenocortical carcinoma.

J. Yokota, T. Sugimura, Y. Tsunematsu, 1992, Journal of the National Cancer Institute.

Absence of p51 mutation in human hepatocellular carcinoma.

J. Yokota, S. Ikawa, Y. Morishita, 2000, Cancer letters.

Identification of CpG islands hypermethylated in human lung cancer by the arbitrarily primed-PCR method

J. Yokota, T. Kohno, J. Inazawa, 1998, Human Genetics.

Association of amino acid substitution polymorphisms in DNA repair genes TP53, POLI, REV1 and LIG4 with lung cancer risk

J. Yokota, T. Kohno, R. Saito, 2005, International journal of cancer.

A Nucleolar Stress–Specific p53–miR-101 Molecular Circuit Functions as an Intrinsic Tumor-Suppressor Network

J. Yokota, C. Harris, T. Kohno, 2018, EBioMedicine.

Prevalence of human papillomavirus 16/18/33 infection and p53 mutation in lung adenocarcinoma

J. Yokota, T. Kohno, R. Iwakawa, 2010, Cancer science.

Significantly mutated genes and regulatory pathways in SCLC-a meta-analysis.

F. Liang, J. Yokota, T. Kohno, 2017, Cancer genetics.

Small Cell Lung Cancer: Can Recent Advances in Biology and Molecular Biology Be Translated into Improved Outcomes?

G. Giaccone, M. Krasnow, C. Rudin, 2022 .

Resistance to anticancer drugs in NIH3T3 cells transfected with c-myc and/or c-H-ras genes.

M. Shibuya, J. Yokota, N. Saijo, 1991, British Journal of Cancer.

Heterogeneity of lung cancer cells with respect to the amplification and rearrangement of myc family oncogenes.

J. Yokota, Teruhiko Yoshida, M. Noguchi, 1988, Oncogene.

MYC Amplification as a Prognostic Marker of Early-Stage Lung Adenocarcinoma Identified by Whole Genome Copy Number Analysis

J. Yokota, T. Kohno, S. Ogawa, 2010, Clinical Cancer Research.

Amplification and expression of a cellular oncogene (c-myc) in human gastric adenocarcinoma cells

J. Yokota, M. Shibuya, Y. Ueyama, 1985, Molecular and cellular biology.

A Two‐Gene Prognostic Classifier for Early‐Stage Lung Squamous Cell Carcinoma in Multiple Large‐Scale and Geographically Diverse Cohorts

A. Gemma, M. Seike, E. Bowman, 2017, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma

Y. Miyagi, Y. Kamatani, Y. Okada, 2016, Nature Communications.

An Integrated Prognostic Classifier for Stage I Lung Adenocarcinoma Based on mRNA, microRNA, and DNA Methylation Biomarkers

David Petersen, Naoto Tsuchiya, Vidar Skaug, 2015, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Development of lung adenocarcinomas with exclusive dependence on oncogene fusions.

J. Yokota, T. Kohno, Teruhiko Yoshida, 2015, Cancer research.

MYO18B, a candidate tumor suppressor gene at chromosome 22q12.1, deleted, mutated, and methylated in human lung cancer

J. Minna, N. Yanaihara, J. Yokota, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Physical and transcriptional map of a 311-kb segment of chromosome 18q21, a candidate lung tumor suppressor locus.

M. Yamazaki, Y. Fukuzumi, Y. Fujimori, 2001, Genomics.

Allelotype of neuroblastoma.

J. Yokota, T. Kohno, Y. Hayashi, 1995, Oncogene.

Pipeline design to identify key features and classify the chemotherapy response on lung cancer patients using large-scale genetic data

Ricard Gavaldà, Vicent J. Ribas, Xavier Rafael-Palou, 2018, BMC Systems Biology.

Localization of a human lung adenocarcinoma susceptibility locus, possibly syntenic to the mouse Pas1 locus, in the vicinity of the D12S1034 locus on chromosome 12p11.2-p12.1.

J. Yokota, T. Kohno, N. Sunaga, 2002, Carcinogenesis.

Therapeutic Priority of the PI3K/AKT/mTOR Pathway in Small Cell Lung Cancers as Revealed by a Comprehensive Genomic Analysis

Hironobu Ohmatsu, Shingo Matsumoto, Akiko Takahashi, 2014, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women.

Hongbing Shen, Chien-Jen Chen, N. Rothman, 2016, Human molecular genetics.

Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types.

Jian Su, Wen Tan, Paolo Vineis, 2015, Journal of the National Cancer Institute.

Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for 13 Cancer Types

Alison P. Klein, William Wheeler, Li Jin, 2015 .

A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population

Yusuke Nakamura, Koichi Goto, Koji Tsuta, 2012, Nature Genetics.

Contribution of the TP53, OGG1, CHRNA3, and HLA-DQA1 Genes to the Risk for Lung Squamous Cell Carcinoma

Seiichiro Yamamoto, Jun Yokota, Takashi Kohno, 2011, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Individuals susceptible to lung adenocarcinoma defined by combined HLA-DQA1 and TERT genotypes.

Koichi Goto, Yutaka Nishiwaki, Seiichiro Yamamoto, 2010, Carcinogenesis.

Contribution of nicotine acetylcholine receptor polymorphisms to lung cancer risk in a smoking-independent manner in the Japanese.

J. Yokota, T. Kohno, Y. Nishiwaki, 2009, Carcinogenesis.

Contribution of the NQO1 and GSTT1 polymorphisms to lung adenocarcinoma susceptibility.

J. Yokota, T. Kohno, N. Sunaga, 2002, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

CYP2A6 gene deletion reduces susceptibility to lung cancer.

J. Yokota, H. Dosaka-akita, T. Kamataki, 1999, Biochemical and biophysical research communications.

Identification of a function-specific mutation of clathrin heavy chain (CHC) required for p53 transactivation.

J. Yokota, S. Yokoyama, M. Shirouzu, 2009, Journal of molecular biology.

ING2 is upregulated in colon cancer and increases invasion by enhanced MMP13 expression

N. Yanaihara, E. Bowman, K. Kumamoto, 2009, International journal of cancer.

A novel PHD-finger motif protein, p47ING3, modulates p53-mediated transcription, cell cycle control, and apoptosis

J. Yokota, C. Harris, S. Okamura, 2003, Oncogene.

Advances in Brief p 29 ING 4 and p 28 ING 5 Bind to p 53 and p 300 , and Enhance p 53 Activity

J. Yokota, C. Harris, E. Appella, 2003 .

Angiogenic activity of the recombinant hst-1 protein.

S. Hirohashi, J. Yokota, H. Sakamoto, 1994, Cancer letters.

Nutlin-3a activates p53 to both down-regulate inhibitor of growth 2 and up-regulate mir-34a, mir-34b, and mir-34c expression, and induce senescence.

Izumi Horikawa, Jun Yokota, Seiichi Takenoshita, 2008, Cancer research.

Association of p16 Homozygous Deletions with Clinicopathologic Characteristics and EGFR/KRAS/p53 Mutations in Lung Adenocarcinoma

Kenji Suzuki, J. Yokota, T. Kohno, 2008, Clinical Cancer Research.

Association of the OGG1‐Ser326Cys polymorphism with lung adenocarcinoma risk

J. Yokota, T. Kohno, R. Saito, 2006, Cancer science.

KIF5B-RET fusions in lung adenocarcinoma

Yasushi Totoki, Koji Tsuta, Shun-ichi Watanabe, 2012, Nature Medicine.

Establishment of human osteosarcoma cell lines with high metastatic potential to lungs and their utilities for therapeutic studies on metastatic osteosarcoma

J. Yokota, H. Moriya, H. Tsuda, 2004, Clinical & Experimental Metastasis.

Biological properties and gene expression associated with metastatic potential of human osteosarcoma

J. Yokota, S. Ohwada, K. Aoyagi, 2004, Clinical & Experimental Metastasis.

BREK/LMTK2 is a myosin VI‐binding protein involved in endosomal membrane trafficking

O. Ohara, J. Yokota, K. Sutoh, 2008, Genes to cells : devoted to molecular & cellular mechanisms.

p53 gene mutations in gastric cancer metastases and in gastric cancer cell lines derived from metastases.

S. Hirohashi, J. Yokota, Teruhiko Yoshida, 1991, Cancer research.

N-cadherin expression is a potential survival mechanism of gefitinib-resistant lung cancer cells.

S. Miyano, J. Yokota, T. Kohno, 2011, American journal of cancer research.

Involvement of LKB1 in epithelial-mesenchymal transition (EMT) of human lung cancer cells.

J. Yokota, T. Kohno, T. Akiyama, 2010, Lung cancer.

Evaluation of a whole‐genome amplification method based on adaptor‐ligation PCR of randomly sheared genomic DNA

J. Yokota, T. Kohno, Teruhiko Yoshida, 2003, Genes, chromosomes & cancer.

Combination of protein coding and noncoding gene expression as a robust prognostic classifier in stage I lung adenocarcinoma.

A. Schetter, E. Bowman, J. Yokota, 2013, Cancer research.

Correlation between histone acetylation and expression of the MYO18B gene in human lung cancer cells

Masahiko Shiraishi, Jun Yokota, Takashi Kohno, 2004, Genes, chromosomes & cancer.

Specificity of proto-oncogene amplification in human malignant diseases.

J. Yokota, S. Meltzer, H. Battifora, 1987, Molecular biology & medicine.

Genome-wide identification of genes with amplification and/or fusion in small cell lung cancer

J. Yokota, Y. Totoki, T. Kohno, 2013, Genes, chromosomes & cancer.

Y chromosome abnormality in human stomach and lung cancer.

J. Yokota, T. Sugimura, H. Mizoguchi, 1987, Japanese journal of cancer research : Gann.

A novel gene, MEL1, mapped to 1p36.3 is highly homologous to the MDS1/EVI1 gene and is transcriptionally activated in t(1;3)(p36;q21)-positive leukemia cells.

J. Yokota, M. Taniwaki, T. Nagasawa, 2000, Blood.

Identification of breakpoint cluster regions at 1p36.3 and 3q21 in hematologic malignancies with t(1;3)(p36;q21)

J. Yokota, B. Johansson, M. Taniwaki, 2000, Genes, chromosomes & cancer.

Molecular karyotype (amplotype) of metastatic colorectal cancer by unbiased arbitrarily primed PCR DNA fingerprinting.

J. Yokota, T. Sekiya, M. Perucho, 1998, Proceedings of the National Academy of Sciences of the United States of America.

ECT2 amplification and overexpression as a new prognostic biomarker for early-stage lung adenocarcinoma

J. Yokota, M. Noguchi, T. Iijima, 2014, Cancer science.

Multistage carcinogenesis : involvement of tumour suppressor genes in the genesis and progression of human cancer : Metastases

J. Yokota, 1994 .

in acute myelogenous leukemias with inv(3)(q21q26) at 3q21 associated with the transcriptional activation of the EVI1 gene Identification of a breakpoint cluster region 3' of the ribophorin I gene

J. Yokota, N. Kamada, S. Asano, 2011 .

Phenotypic alterations of small cell lung carcinoma induced by different levels of wild-type p53 expression

J. Yokota, T. Kohno, Y. Tomizawa, 1998, Cell Death and Differentiation.

Deficiency of antiproliferative family protein Ana correlates with development of lung adenocarcinoma

J. Yokota, Toru Suzuki, K. Mitsumori, 2009, Cancer science.

Inhibition of lung cancer cell growth and induction of apoptosis after reexpression of 3p21.3 candidate tumor suppressor gene SEMA3B

J. Minna, J. Yokota, A. Gazdar, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Genetic polymorphisms and alternative splicing of the hOGG1 gene, that is involved in the repair of 8-hydroxyguanine in damaged DNA

J. Yokota, T. Kohno, H. Sugimura, 1998, Oncogene.

TSPAN2 is involved in cell invasion and motility during lung cancer progression.

J. Yokota, T. Kohno, T. Ochiya, 2014, Cell reports.

TSPAN12 is a critical factor for cancer–fibroblast cell contact-mediated cancer invasion

J. Yokota, T. Kohno, T. Ochiya, 2014, Proceedings of the National Academy of Sciences.

Use of a cytokine gene expression signature in lung adenocarcinoma and the surrounding tissue as a prognostic classifier.

Leah E. Mechanic, Krista A. Zanetti, X. Wang, 2007, Journal of the National Cancer Institute.

Loss of Keap1 function activates Nrf2 and provides advantages for lung cancer cell growth.

S. Hirohashi, J. Yokota, T. Shibata, 2008, Cancer research.

Mutation and expression of the beta-catenin-interacting protein ICAT in human colorectal tumors.

J. Yokota, T. Akiyama, Y. Morishita, 2002, Japanese journal of clinical oncology.

Identification of tumor markers and differentiation markers for molecular diagnosis of lung adenocarcinoma

J. Yokota, T. Kohno, Y. Matsuno, 2006, Oncogene.

Frequent EGFR mutations in noninvasive bronchioloalveolar carcinoma

Kenji Suzuki, J. Yokota, T. Kohno, 2006, International journal of cancer.

Friend erythroleukaemia cell mutants defective in viral gene expression.

J. Yokota, A. Iwamoto, A. Suzuki, 1984, The Journal of general virology.

NEK9-dependent proliferation of cancer cells lacking functional p53

J. Yokota, T. Kohno, T. Ochiya, 2014, Scientific Reports.

Involvement of Ku80 in microhomology-mediated end joining for DNA double-strand breaks in vivo.

J. Yokota, T. Kohno, Masanori Sato, 2007, DNA repair.

Hepatocyte Growth Factor Expression in EGFR Mutant Lung Cancer with Intrinsic and Acquired Resistance to Tyrosine Kinase Inhibitors in a Japanese Cohort

J. Yokota, M. Oda, Y. Yatabe, 2011, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

The usefulness of mutation-specific antibodies in detecting epidermal growth factor receptor mutations and in predicting response to tyrosine kinase inhibitor therapy in lung adenocarcinoma.

Kenji Suzuki, J. Yokota, T. Kohno, 2011, Lung cancer.

Identification of genes (SPON2 and C20orf2) differentially expressed between cancerous and noncancerous lung cells by mRNA differential display.

J. Yokota, T. Kohno, Y. Matsuno, 1999, Genomics.

Utility of serum DNA and pyrosequencing for the detection of EGFR mutations in non-small cell lung cancer.

Hakan Akca, Jun Yokota, J. Yokota, 2013, Cancer genetics.

CUB Domain-Containing Protein 1 Is a Novel Regulator of Anoikis Resistance in Lung Adenocarcinoma

J. Yokota, R. Sakai, T. Kiyono, 2007, Molecular and Cellular Biology.

Chronic myelomonocytic leukemia with a chromosome abnormality (46,XY,20q–) in all dividing myeloid cells: Evidence for clonal origin in a multipotent stem cell common to granulocyte, monocyte, erythrocyte, and thrombocyte

J. Yokota, S. Asano, K. Morishita, 1983, American journal of hematology.

A single nucleotide polymorphism at the splice donor site of the human MYH base excision repair gene results in reduced translation efficiency of its transcripts

J. Yokota, H. Kuwano, S. Takenoshita, 2002, Genes to cells : devoted to molecular & cellular mechanisms.

Genetic variants associated with longer telomere length are associated with increased lung cancer risk among never‐smoking women in Asia: a report from the female lung cancer consortium in Asia

B. Qian, Hongbing Shen, Chien-Jen Chen, 2015, International journal of cancer.

Stage-dependent evaluation of microsatellite instability in gastric carcinoma with familial clustering.

J. Yokota, H. Sugimura, K. Kanazawa, 1997, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Homozygous deletion at chromosome 2q33 in human small-cell lung carcinoma identified by arbitrarily primed PCR genomic fingerprinting.

J. Yokota, T. Kohno, D. Shapiro, 1994, Oncogene.

Association of CYP19A1 polymorphisms with risks for atypical adenomatous hyperplasia and bronchioloalveolar carcinoma in the lungs.

Kenji Suzuki, J. Yokota, T. Kohno, 2010, Carcinogenesis.

Association of DNA repair gene polymorphisms with response to platinum-based doublet chemotherapy in patients with non-small-cell lung cancer.

J. Yokota, T. Kohno, Y. Ohe, 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Genetic pathways to human cancer

J. Yokota, W. Yasui, H. Ohgaki, 2003 .

A full genome scan for gastric cancer

J. Yokota, T. Kohno, Y. Maehara, 2005, Journal of Medical Genetics.

Identification and Characterization of a New Phospholipase C-like Protein, PLC-L2

Jun Yokota, Takashi Kohno, Kiyoko Fukami, 1999 .

Identification and characterization of a new phospholipase C-like protein, PLC-L(2).

J. Yokota, T. Kohno, T. Takenawa, 1999, Biochemical and biophysical research communications.

Multiple steps in carcinogenesis involving alterations of multiple tumor suppressor genes

J. Yokota, Takashi Sugimura, Takashi Sugimura, 1993, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Requirement of ATM for Rapid p53 Phosphorylation at Ser46 without Ser/Thr-Gln Sequences

J. Yokota, Y. Taya, T. Hirota, 2010, Molecular and Cellular Biology.

Differential ability of polymorphic OGG1 proteins to suppress mutagenesis induced by 8-hydroxyguanine in human cell in vivo.

J. Yokota, T. Kohno, N. Sunaga, 2004, Carcinogenesis.

Molecular cloning of a novel NF2/ERM/4.1 superfamily gene, ehm2, that is expressed in high-metastatic K1735 murine melanoma cells.

J. Yokota, K. Shimizu, Y. Nagamachi, 2000, Genomics.

The OGG1 gene encodes a repair enzyme for oxidatively damaged DNA and is involved in human carcinogenesis.

J. Yokota, K. Shinmura, J Yokota, 2001, Antioxidants & redox signaling.

Germline p53 mutation in a patient with multiple primary cancers.

J. Yokota, T. Hasegawa, K. Shinmura, 2001, Japanese journal of clinical oncology.

Population-based mapping of pulmonary adenoma susceptibility 1 locus.

S. Hirohashi, J. Yokota, T. Mitsudomi, 2000, Cancer research.

Profiling of actionable gene alterations in ovarian cancer by targeted deep sequencing.

N. Yanaihara, A. Okamoto, J. Yokota, 2015, International journal of oncology.

Cloning of a human homolog of the yeast OGG1 gene that is involved in the repair of oxidative DNA damage

J. Yokota, T. Kohno, M. Taniwaki, 1997, Oncogene.

BET-Inhibitor I-BET762 and PARP-Inhibitor Talazoparib Synergy in Small Cell Lung Cancer Cells

J. Yokota, L. Bagella, I. Marchesi, 2020, International journal of molecular sciences.

Identification of translocational breakpoints within the intron region before the last coding exon (exon 12) of the EVI1 gene in two cases of CML-BC with inv(3)(q21q26).

J. Yokota, N. Kamada, T. Taki, 1997, Genomics.

The human thrombopoietin gene is located on chromosome 3q26.33-q27, but is not transcriptionally activated in leukemia cells with 3q21 and 3q26 abnormalities (3q21q26 syndrome).

J. Yokota, H. Satoh, M. Taniwaki, 1995, Leukemia.

Quantification of epigenetic and genetic 2nd hits in CDH1 during hereditary diffuse gastric cancer syndrome progression.

J. Yokota, D. Huntsman, J. Senz, 2009, Gastroenterology.

Studies Combination of Protein Coding and Noncoding Gene Expression as a Robust Prognostic Classi fi er in Stage I Lung Adenocarcinoma

A. Schetter, E. Bowman, J. Yokota, 2013 .

Clinical Studies Combination of Protein Coding and Noncoding Gene Expression as a Robust Prognostic Classi fi er in Stage I Lung Adenocarcinoma

A. Schetter, E. Bowman, J. Yokota, 2013 .

Identification of genes whose expression is upregulated in lung adenocarcinoma cells in comparison with type II alveolar cells and bronchiolar epithelial cells in vivo

J. Yokota, T. Kohno, M. Nakamoto, 2004, Oncogene.

Microsatellite instability in primary and metastatic colorectal cancers

J. Yokota, T. Muto, M. Shiseki, 1995, International journal of cancer.

The autocrine motility factor receptor gene encodes a novel type of seven transmembrane protein 1

J. Yokota, A. Raz, S. Ohwada, 1999, FEBS letters.

KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer.

F. Setién, M. Esteller, J. Yokota, 2015, Cancer research.

KAT 6 B Is a Tumor Suppressor Histone H 3 Lysine 23 Acetyltransferase UndergoingGenomic Loss in Small Cell Lung Cancer

F. Setién, M. Esteller, J. Yokota, 2015 .

Association of polymorphisms in the MTH1 gene with small cell lung carcinoma risk.

J. Yokota, T. Kohno, Y. Nishiwaki, 2006, Carcinogenesis.

Homozygous deletion and reduced expression of the DOCK8 gene in human lung cancer.

J. Minna, J. Yokota, T. Kohno, 2006, International journal of oncology.

Decreased TCGF activity in the culture medium of PHA stimulated peripheral mononuclear cells from patients with metastatic cancer.

J. Yokota, S. Asano, S. Miwa, 1983, Clinical and experimental immunology.

Garcinol, a Histone Acetyltransferase Inhibitor, Radiosensitizes Cancer Cells by Inhibiting Nonhomologous End Joining

J. Yokota, H. Ogiwara, T. Kohno, 2012 .

Garcinol, a histone acetyltransferase inhibitor, radiosensitizes cancer cells by inhibiting non-homologous end joining.

Takashi Nakano, Jun Yokota, Takashi Kohno, 2012, International journal of radiation oncology, biology, physics.

Advances in Brief Population-based Mapping of Pulmonary Adenoma Susceptibility 1 Locus 1

S. Hirohashi, J. Yokota, T. Mitsudomi, 2000 .

Frequent EGFR mutations in brain metastases of lung adenocarcinoma

J. Yokota, T. Kohno, R. Iwakawa, 2006, International journal of cancer.

Identification of D19S246 as a novel lung adenocarcinoma susceptibility locus by genome survey with 10-cM resolution microsatellite markers.

J. Yokota, T. Kohno, R. Saito, 2003, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Identification of D 19 S 246 as a Novel Lung Adenocarcinoma Susceptibility Locus by Genome Survey with 10-cM Resolution Microsatellite Markers 1

J. Yokota, T. Kohno, R. Saito, 2003 .

Comprehensive analysis of p53 gene mutation characteristics in lung carcinoma with special reference to histological subtypes.

J. Yokota, T. Kohno, Y. Tomizawa, 1999, International journal of oncology.

Genetic heterogeneity of chromosome 11 associated with tumorigenicity in HeLa D98-OR cells.

M. Oshimura, A. Okamoto, J. Yokota, 1995, Cancer genetics and cytogenetics.

hOGG 1 Ser 326 Cys Polymorphism and Lung Cancer Susceptibility 1

B. Morris, J. Yokota, T. Kohno, 1999 .

HPV-associated lung cancers: an international pooled analysis.

F. Khuri, J. Yokota, D. Spandidos, 2014, Carcinogenesis.

Smoking and Genetic Risk Variation Across Populations of European, Asian, and African American Ancestry—A Meta‐Analysis of Chromosome 15q25

Ming D. Li, John P. Rice, Yan V. Sun, 2012, Genetic epidemiology.

Genetic polymorphism of CYP2D6 in the Japanese population.

J. Yokota, T. Kamataki, F. Gonzalez, 1999, Pharmacogenetics.

Segregation Analysis of Gastric Cancer in a Japanese Population

R. Elston, J. Yokota, M. Kanamori, 2001 .

Loss of functional E-cadherin renders cells more resistant to the apoptotic agent taxol in vitro.

M. Gleave, J. Yokota, D. Huntsman, 2005, Experimental cell research.

Deletion mapping of chromosome 2 in human lung carcinoma

S. Hirohashi, J. Yokota, T. Kohno, 1996, Genes, chromosomes & cancer.

Loss of heterozygosity on chromosomes 1p and 11p in sporadic pheochromocytoma.

J. Yokota, T. Sugimura, M. Tsutsumi, 1989, Journal of the National Cancer Institute.

Genomic structure and chromosomal localization of the mouse Ogg1 gene that is involved in the repair of 8-hydroxyguanine in DNA damage

S. Wakana, J. Yokota, T. Kohno, 2009, Mammalian Genome.

Infrequent Mutations of the hOGG1 Gene, That Is Involved in the Excision of 8‐Hydroxyguanine in Damaged DNA, in Human Gastric Cancer

J. Yokota, T. Kohno, H. Sugimura, 1998, Japanese journal of cancer research : Gann.

Adenine excisional repair function of MYH protein on the adenine:8-hydroxyguanine base pair in double-stranded DNA.

J. Yokota, S. Yamaguchi, T. Nohmi, 2000, Nucleic acids research.

Analysis of replication error (RER+) phenotypes in cervical carcinoma.

S. Kern, G. Hampton, J. Yokota, 1996, Cancer research.

Enhancement of OGG1 protein AP lyase activity by increase of APEX protein.

J. Yokota, S. Yamaguchi, K. Shinmura, 2001, Mutation research.

Possible role of protein kinase C in the regulation of intracellular stability of focal adhesion kinase in mouse 3T3 cells

J. Yokota, J. Fujimoto, A. Mogi, 1995, FEBS letters.

Stimulation of tyrosine‐ and serine‐phosphorylation of focal adhesion kinase in mouse 3T3 cells by fibronectin and fibroblast growth factor

J. Yokota, Y. Yaoi, A. Mogi, 1994, FEBS letters.

Oncogene and Tumor Suppressor Gene.

J. Yokota, T. Muto, H. Yuki, 1991 .

Differentiation induced by RB expression and apoptosis induced by p53 expression in an osteosarcoma cell line

J. Yokota, S. Tsuchida, K. Ookawa, 1997, Oncogene.

Abstract 5721: Garcinol, a histone acetyltransferase inhibitor, radiosensitizes cancer cells by inhibiting non-homologous end joining

J. Yokota, H. Ogiwara, T. Kohno, 2012 .

Reduced Levels of ATF-2 Predispose Mice to Mammary Tumors

Koichi Nagasaki, Yoshio Miki, Shintaro Nomura, 2006, Molecular and Cellular Biology.

Two regions of homozygous deletion clusters at chromosome band 9p21 in human lung cancer

J. Minna, M. Yamazaki, H. Tashiro, 2000, Genes, chromosomes & cancer.

Contribution of the NQO 1 and GSTT 1 Polymorphisms to Lung Adenocarcinoma Susceptibility 1

J. Yokota, T. Kohno, N. Sunaga, 2002 .

Inactivation of p16(INK4) in hepatocellular carcinoma

S. Hirohashi, J. Yokota, Y. Kanai, 1996 .

Contribution of germline mutations to PARK2 gene inactivation in lung adenocarcinoma

J. Yokota, T. Kohno, S. Ogawa, 2012, Genes, chromosomes & cancer.

Microsatellite instability in gastric cancer prone families.

K. Maruyama, J. Yokota, H. Katai, 1996, Cancer letters.

Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines.

J. Yokota, T. Kohno, Y. Hayashi, 2000, Leukemia research.

Abstract A61: MiR-101 as a molecular switch for sequential activation of p53-dependent G1 and G2 checkpoints in response to ribosomal stress

J. Yokota, T. Kohno, Y. Fujiwara, 2013 .

Expression of granulocyte and granulocyte-macrophage colony-stimulating factors by human non-hematopoietic tumor cells.

J. Yokota, Y. Ueyama, S. Nagata, 1990, Growth factors.

BET inhibition is an effective approach against KRAS-driven PDAC and NSCLC

J. Yokota, B. Haendler, J. Whitfield, 2018, Oncotarget.

Electronic Microarray Technique for Detection of Nine Base Substitutions including Single-nucleotide Poly- Morphisms in the Human Ogg1 Gene, Zhilong Gong, 1#

J. Yokota, T. Kohno, X. Le, 2004 .

Oncogenic Ras/ERK Signaling Activates CDCP1 to Promote Tumor Invasion and Metastasis

J. Yokota, R. Sakai, H. Tsuda, 2014, Molecular Cancer Research.

Oncogenes and Tumor Suppressors Oncogenic Ras / ERK Signaling Activates CDCP 1 to Promote Tumor Invasion and Metastasis

J. Yokota, R. Sakai, H. Tsuda, 2014 .

Alterations of glycolipids of human leukemia cell line HL-60 during differentiation.

J. Yokota, T. Momoi, 1983, Journal of the National Cancer Institute.

Comparative allelotype of early and advanced stage non‐small cell lung carcinomas

S. Hirohashi, J. Yokota, T. Kohno, 1996, Genes, chromosomes & cancer.

Concordant p53 and DCC alterations and allelic losses on chromosomes 13q and 14q associated with liver metastases of colorectal carcinoma

S. Hirohashi, J. Yokota, K. Ookawa, 1993, International journal of cancer.

Bronchioloalveolar Carcinoma (Lepidic Growth) Component Is a More Useful Prognostic Factor than Lymph Node Metastasis

Kenji Suzuki, J. Yokota, M. Noguchi, 2009, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Clonality and heterogeneity of pulmonary blastoma from the viewpoint of genetic alterations: a case report.

J. Yokota, T. Kohno, Y. Arai, 2007, Lung cancer.

Expression of the OGG1-type 1a (nuclear form) protein in cancerous and non-cancerous human cells.

J. Yokota, T. Kohno, H. Sugimura, 2000, International journal of oncology.

Status of deleted in colorectal cancer gene expression correlates with neuroblastoma metastasis.

J. Yokota, P. Lin, M. Reyes-Múgica, 1998, Laboratory investigation; a journal of technical methods and pathology.

Allelic losses associated with the metastatic potential of colorectal-carcinoma.

S. Hirohashi, J. Yokota, T. Muto, 1994, International journal of oncology.

Point Mutations of the Mxil Gene are Rare in Prostate Cancers

J. Yokota, S. Wilczynski, N. Kawamata, 1996, The Prostate.

Deletion mapping of chromosomes 14q and 1p in human neuroblastoma.

M. Schwab, Y. Nakamura, J. Yokota, 1992, Oncogene.