Yusu Gu

发表

MicroRNA-133 controls cardiac hypertrophy

C. Croce, M. Latronico, D. Catalucci, 2007, Nature Medicine.

Tbx20 regulates a genetic program essential to adult mouse cardiomyocyte function.

G. Wang, John M Westlund, M. Nóbrega, 2011, The Journal of clinical investigation.

ErbB2 is essential in the prevention of dilated cardiomyopathy

Susumu Minamisawa, Kuo-Fen Lee, John Ross, 2002, Nature Medicine.

Desmosomal COP9 regulates proteome degradation in arrhythmogenic right ventricular dysplasia/cardiomyopathy

Yusu Gu, N. Dalton, K. Peterson, 2021, The Journal of clinical investigation.

Loss of Enigma Homolog Protein Results in Dilated Cardiomyopathy

Yusu Gu, N. Dalton, K. Peterson, 2010, Circulation research.

Global disturbances in autonomic function yield cardiovascular instability and hypertension in the chromogranin a null mouse.

D. O'Connor, Yusu Gu, S. Mahata, 2009, Endocrinology.

An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice.

A. McCulloch, Yusu Gu, N. Dalton, 2008, The Journal of clinical investigation.

Analysis and validation of traits associated with a single nucleotide polymorphism Gly364Ser in catestatin using humanized chromogranin A mouse models

Yusu Gu, T. Rieg, Kuixing Zhang, 2016, Journal of hypertension.

Increased Echogenicity and Radiodense Foci on Echocardiogram and MicroCT in Murine Myocarditis

Yusu Gu, N. Dalton, K. Peterson, 2016, PloS one.

Reduction of myocardial ischaemia–reperfusion injury by inactivating oxidized phospholipids

Yusu Gu, N. Dalton, K. Peterson, 2018, Cardiovascular research.

Mitochondrial reprogramming induced by CaMKIIδ mediates hypertrophy decompensation.

Ajit S. Divakaruni, Yusu Gu, N. Dalton, 2015, Circulation research.

function in a mouse model of pulmonary inflammation Impaired exercise capacity and skeletal muscle

W. Roberts, Yusu Gu, N. Dalton, 2015 .

in a mouse model of pulmonary inflammation Impaired exercise capacity and skeletal muscle function

Yusu Gu, N. Dalton, K. Peterson, 2013 .

Impaired exercise capacity and skeletal muscle function in a mouse model of pulmonary inflammation.

Yusu Gu, N. Dalton, K. Peterson, 2013, Journal of applied physiology.

Aortic pathology from protein kinase G activation is prevented by an antioxidant vitamin B12 analog

Yusu Gu, N. Dalton, K. Peterson, 2019, Nature Communications.

(cid:1) 1 Integrin Gene Excision in the Adult Murine Cardiac Myocyte Causes Defective Mechanical and Signaling Responses

Yusu Gu, N. Dalton, K. Peterson, 2012 .

Lmo7 is dispensable for skeletal muscle and cardiac function.

Yusu Gu, N. Dalton, K. Peterson, 2015, American journal of physiology. Cell physiology.

Lmo 7 is dispensable for skeletal muscle and cardiac function

Yusu Gu, N. Dalton, K. Peterson, 2015 .

Apoptosis and oncosis in the early progression of left ventricular dysfunction in the cardiomyopathic hamster

M. Martone, Sam S. Oh, Yusu Gu, 2002, Basic Research in Cardiology.

Ca2+/Calmodulin-Dependent Protein Kinase II &dgr; Mediates Myocardial Ischemia/Reperfusion Injury Through Nuclear Factor-&kgr;B

Yusu Gu, N. Dalton, K. Peterson, 2013, Circulation research.

Impaired mitophagy facilitates mitochondrial damage in Danon disease.

Ajit S. Divakaruni, Kenneth L. Jones, Yusu Gu, 2017, Journal of molecular and cellular cardiology.

Discoidin domain receptor 2 germline gene deletion leads to altered heart structure and function in the mouse.

Yusu Gu, N. Dalton, K. Peterson, 2014, American journal of physiology. Heart and circulatory physiology.

Restoration of Deficient Membrane Proteins in the Cardiomyopathic Hamster by In Vivo Cardiac Gene Transfer

J. Ross, Sam S. Oh, Yusu Gu, 2002, Circulation.

Systemic AAV9.LAMP2B injection reverses metabolic and physiologic multiorgan dysfunction in a murine model of Danon disease

Yusu Gu, N. Dalton, K. Peterson, 2020, Science Translational Medicine.

Heart-targeted overexpression of caspase3 in mice increases infarct size and depresses cardiac function

M. Todaro, G. Stassi, C. Croce, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice.

Tong Zhang, Ju Chen, Yusu Gu, 2009, The Journal of clinical investigation.

Delta-Sarcoglycan Gene Therapy Halts Progression of Cardiac Dysfunction, Improves Respiratory Failure, and Prolongs Life in Myopathic Hamsters

Mark Ellisman, J. Ross, Yusu Gu, 2011, Circulation. Heart failure.

Desmosomal junctions are necessary for adult sinus node function.

A. McCulloch, Yusu Gu, N. Dalton, 2016, Cardiovascular research.

Loss-of-function mutations in co-chaperone BAG3 destabilize small HSPs and cause cardiomyopathy

Yusu Gu, N. Dalton, K. Peterson, 2017, The Journal of clinical investigation.

The Muscle Ankyrin Repeat Proteins CARP, Ankrd2, and DARP Are Not Essential for Normal Cardiac Development and Function at Basal Conditions and in Response to Pressure Overload

M. Bang, Yusu Gu, N. Dalton, 2014, PloS one.

The cardiovascular physiologic actions of urocortin II: acute effects in murine heart failure.

Yusu Gu, N. Dalton, K. Peterson, 2004, Proceedings of the National Academy of Sciences of the United States of America.

FHL2 (SLIM3) Is Not Essential for Cardiac Development and Function

J. Ross, Yusu Gu, Ju Chen, 2000, Molecular and Cellular Biology.

Sarcoplasmic reticulum calcium defect in Ras-induced hypertrophic cardiomyopathy heart.

J. Ross, Yusu Gu, K. Chien, 2004, American journal of physiology. Heart and circulatory physiology.

Cardiomyocyte Expression of ZO-1 Is Essential for Normal Atrioventricular Conduction but Does Not Alter Ventricular Function

A. McCulloch, Yusu Gu, N. Dalton, 2020, Circulation research.

cardiomyopathy with premature death

M. Bang, Yusu Gu, N. Dalton, 2008 .

Hypertension from targeted ablation of chromogranin A can be rescued by the human ortholog.

D. O'Connor, J. Ross, Yusu Gu, 2005, The Journal of clinical investigation.

Normalization of Naxos plakoglobin levels restores cardiac function in mice.

Yusu Gu, N. Dalton, K. Peterson, 2015, The Journal of clinical investigation.

Combined loss of obscurin and obscurin-like 1 in murine hearts results in impaired diastolic dysfunction, altered metabolism and deregulated mitophagy

Yusu Gu, N. Dalton, F. Sheikh, 2022, bioRxiv.

Talin1 Has Unique Expression versus Talin 2 in the Heart and Modifies the Hypertrophic Response to Pressure Overload*

Yusu Gu, K. Peterson, A. Samarel, 2012, The Journal of Biological Chemistry.

PRDM16 Is a Compact Myocardium-Enriched Transcription Factor Required to Maintain Compact Myocardial Cardiomyocyte Identity in Left Ventricle

Yusu Gu, Xiang-Dong Fu, Ju Chen, 2021, Circulation.

Desmosomal COP 9 regulates proteome degradation in arrhythmogenic right ventricular dysplasia / cardiomyopathy

Tomoo, Yusu Gu, N. Dalton, 2021 .

Prion-Induced Amyloid Heart Disease with High Blood Infectivity in Transgenic Mice

E. Masliah, B. Chesebro, Yusu Gu, 2006, Science.

Constitutive protein kinase G activation exacerbates stress‐induced cardiomyopathy

Yusu Gu, N. Dalton, G. Boss, 2021, British journal of pharmacology.

A nitric oxide‐releasing derivative of enalapril, NCX 899, prevents progressive cardiac dysfunction and remodeling in hamsters with heart failure

J. Ross, G. Condorelli, Yusu Gu, 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Pulmonary artery pressure responses to increased cardiac output in chickens with raised metabolic rate.

J. West, Yusu Gu, K. Peterson, 2010, Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.

Combined loss of obscurin and obscurin-like 1 in murine hearts results in diastolic dysfunction, altered metabolism and deregulated mitophagy

Yusu Gu, N. Dalton, F. Sheikh, 2022, bioRxiv.

Muscle‐specific VEGF deficiency greatly reduces exercise endurance in mice

R. A. Howlett, Yusu Gu, N. Dalton, 2009, The Journal of physiology.

Thymosin Beta 4 Is Dispensable for Murine Cardiac Development and Function

Yusu Gu, N. Dalton, K. Peterson, 2012, Circulation research.

Myocardial expression, signaling, and function of GPR22: a protective role for an orphan G protein-coupled receptor.

John Ross, John W. Adams, J. Ross, 2008, American journal of physiology. Heart and circulatory physiology.

The Cardiac-specific Nuclear δB Isoform of Ca2+/Calmodulin-dependent Protein Kinase II Induces Hypertrophy and Dilated Cardiomyopathy Associated with Increased Protein Phosphatase 2A Activity*

Tong Zhang, John Ross, H. Schulman, 2002, The Journal of Biological Chemistry.

A Defect in the Kv Channel-Interacting Protein 2 (KChIP2) Gene Leads to a Complete Loss of I to and Confers Susceptibility to Ventricular Tachycardia

J. Ross, Yusu Gu, W. Giles, 2001, Cell.

A secretory pathway kinase regulates sarcoplasmic reticulum Ca2+ homeostasis and protects against heart failure

Yusu Gu, N. Dalton, K. Peterson, 2018, eLife.

Impaired Chronotropic Response to Exercise in Mice Lacking Catecholamines in Adrenergic Cells

Yusu Gu, M. Ziegler, Fujun Liu, 2008, Annals of the New York Academy of Sciences.

Chronic phospholamban inhibition prevents progressive cardiac dysfunction and pathological remodeling after infarction in rats.

J. Chrast, J. Ross, Yusu Gu, 2004, The Journal of clinical investigation.

A cardiac myocyte vascular endothelial growth factor paracrine pathway is required to maintain cardiac function

Yusu Gu, N. Dalton, Yan Huang, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Nebulette knockout mice have normal cardiac function, but show Z-line widening and up-regulation of cardiac stress markers.

M. Bang, Yusu Gu, N. Dalton, 2015, Cardiovascular research.

Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis.

D. Brenner, Yusu Gu, N. Dalton, 2014, The Journal of clinical investigation.

Suppression of Endothelial AGO1 Promotes Adipose Tissue Browning and Improves Metabolic Dysfunction

Gene W. Yeo, Yusu Gu, K. Peterson, 2020, Circulation.

Adipocyte-specific loss of PPARγ attenuates cardiac hypertrophy.

Hsien-Da Huang, Yusu Gu, N. Dalton, 2016, JCI insight.

&agr;-E-Catenin Inactivation Disrupts the Cardiomyocyte Adherens Junction, Resulting in Cardiomyopathy and Susceptibility to Wall Rupture

Yusu Gu, N. Dalton, K. Peterson, 2006, Circulation.

Combinatorial interactions of genetic variants in human cardiomyopathy

Eric D. Adler, Nicholas J. Schork, Adam J. Engler, 2019, Nature Biomedical Engineering.

Chronic suppression of heart-failure progression by a pseudophosphorylated mutant of phospholamban via in vivo cardiac rAAV gene delivery

Masahiko Hoshijima, Susumu Minamisawa, John Ross, 2002, Nature Medicine.

Nesprin 1 is critical for nuclear positioning and anchorage.

Yusu Gu, N. Dalton, K. Peterson, 2010, Human molecular genetics.

Mediator complex proximal Tail subunit MED30 is critical for Mediator core stability and cardiomyocyte transcriptional network

Yusu Gu, T. Boyer, Changming Tan, 2021, PLoS genetics.

Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo.

E. Masliah, Yusu Gu, N. Dalton, 2017, Cell stem cell.

Selective deletion of long but not short Cypher isoforms leads to late-onset dilated cardiomyopathy.

Kensuke Kimura, Ju Chen, Norbert Frey, 2011, Human molecular genetics.

Cardiac-specific ablation of Cypher leads to a severe form of dilated cardiomyopathy with premature death.

Ju Chen, M. Bang, Yusu Gu, 2009, Human molecular genetics.

Coxsackievirus and adenovirus receptor (CAR) mediates atrioventricular-node function and connexin 45 localization in the murine heart.

A. McCulloch, Yusu Gu, N. Dalton, 2008, The Journal of clinical investigation.

Loss of a gp130 Cardiac Muscle Cell Survival Pathway Is a Critical Event in the Onset of Heart Failure during Biomechanical Stress

J. Ross, K. Rajewsky, Yusu Gu, 1999, Cell.

Syncoilin is required for generating maximum isometric stress in skeletal muscle but dispensable for muscle cytoarchitecture.

Ju Chen, Richard L Lieber, M. Bang, 2008, American journal of physiology. Cell physiology.

Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice

J. Ross, Yusu Gu, N. Dalton, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Luma is not essential for murine cardiac development and function

Yusu Gu, N. Dalton, K. Peterson, 2018, Cardiovascular research.

Mouse and computational models link Mlc2v dephosphorylation to altered myosin kinetics in early cardiac disease.

Andrew D McCulloch, Richard L Moss, Ju Chen, 2012, The Journal of clinical investigation.

- oxidation capacity in skeletal muscle β-estradiol have increased β Men supplemented with 17

Yusu Gu, N. Dalton, K. Peterson, 2010 .

Chronic Phospholamban–Sarcoplasmic Reticulum Calcium ATPase Interaction Is the Critical Calcium Cycling Defect in Dilated Cardiomyopathy

M. Martone, J. Ross, Yusu Gu, 1999, Cell.

Atypical ALPK2 kinase is not essential for cardiac development and function.

Yusu Gu, Ju Chen, J. Bogomolovas, 2020, American journal of physiology. Heart and circulatory physiology.

Epinephrine Is Required for Normal Cardiovascular Responses to Stress in the Phenylethanolamine N-Methyltransferase Knockout Mouse

J. Ross, Yusu Gu, N. Dalton, 2007, Circulation.

Urocortin 2 lowers blood pressure and reduces plasma catecholamine levels in mice with hyperadrenergic activity.

D. O'Connor, Yusu Gu, K. Peterson, 2010, Endocrinology.

Intermittent hypoxia and hypercapnia induce pulmonary artery atherosclerosis and ventricular dysfunction in low density lipoprotein receptor deficient mice.

Andrew C. Li, R. Douglas, Yusu Gu, 2013, Journal of applied physiology.

accordance with the recommendations in the Guide for the Care and Use of Laboratory Animals of the National Institutes of Health

Andrew C. Li, R. Douglas, Yusu Gu, 2013 .

LeakRegulation and Physiology of Mitochondrial Proton

Ajit S. Divakaruni, L. Ferrucci, Yusu Gu, 2015 .

Requirement for Ca 2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice (Journal of Clinical Investigation (2009) 119, 5, (1230-1240) doi: 10.1172/JCI38022)

Donald M. Bers, Tong Zhang, Ju Chen, 2012 .

Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications

Jordi Villà-Freixa, Peter Sandner, Bernd J. Pichler, 2017, BMC Pharmacology and Toxicology.

MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice.

M. Latronico, D. Catalucci, G. Condorelli, 2010, The Journal of clinical investigation.

Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice

J. Ross, G. Stassi, C. Croce, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Absence of SOCS3 in the Cardiomyocyte Increases Mortality in a gp130-Dependent Manner Accompanied by Contractile Dysfunction and Ventricular Arrhythmias

Yusu Gu, N. Dalton, K. Peterson, 2011, Circulation.

Increasing Mononuclear Diploid Cardiomyocytes by Loss of E2F Transcription Factor 7/8 Fails to Improve Cardiac Regeneration After Infarct.

Yusu Gu, Ju Chen, S. Evans, 2023, Circulation.

Combinatorial interactions of genetic variants in human cardiomyopathy

Elie N. Farah, N. Schork, Yusu Gu, 2019, Nature Biomedical Engineering.

Infarct Fibroblasts Do Not Derive From Bone Marrow Lineages

Yusu Gu, N. Dalton, K. Peterson, 2017, Circulation research.

Cardiolipin Remodeling Defects Impair Mitochondrial Architecture and Function in a Murine Model of Barth Syndrome Cardiomyopathy

Yusu Gu, Å. Gustafsson, Changming Tan, 2021, Circulation. Heart failure.

DELE1 is protective for mitochondrial cardiomyopathy.

Yusu Gu, S. Evans, K. Ouyang, 2022, Journal of molecular and cellular cardiology.

Connexin defects underlie arrhythmogenic right ventricular cardiomyopathy in a novel mouse model.

A. McCulloch, Yusu Gu, K. Peterson, 2014, Human molecular genetics.

PTPMT1 Is Required for Embryonic Cardiac Cardiolipin Biosynthesis to Regulate Mitochondrial Morphogenesis and Heart Development.

Yusu Gu, Changming Tan, F. Vaz, 2021, Circulation.

erbB2 is required for G protein-coupled receptor signaling in the heart

Yusu Gu, K. Peterson, B. Brar, 2006, Proceedings of the National Academy of Sciences.

Increased Infarct Wall Thickness by a Bio-Inert Material Is Insufficient to Prevent Negative Left Ventricular Remodeling after Myocardial Infarction

Jeffrey H. Omens, Kirk L. Peterson, Yusu Gu, 2011, PloS one.

A Post-transcriptional Compensatory Pathway in Heterozygous Ventricular Myosin Light Chain 2-Deficient Mice Results in Lack of Gene Dosage Effect during Normal Cardiac Growth or Hypertrophy*

Yusu Gu, K. Chien, J. Ross, 1999, The Journal of Biological Chemistry.

Plakophilin‐2 Gene Therapy Prevents Arrhythmogenic Right Ventricular Cardiomyopathy Development In A Novel Mouse Model Harboring Patient Genetics

Yusu Gu, K. Peterson, F. Sheikh, 2021, The FASEB Journal.

Mitochondrial Stress Induces an HRI-eIF2α Pathway Protective for Cardiomyopathy.

Y. Kluger, Yusu Gu, Jun Zhao, 2022, Circulation.

Distinct roles of HF-1b/Sp4 in ventricular and neural crest cells lineages affect cardiac conduction system development.

Masahiko Hoshijima, Kenneth R Chien, Monica Zamora, 2006, Developmental biology.

Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications

James C. Campbell, Dong I. Lee, M. Zaccolo, 2017, BMC Pharmacology and Toxicology.

In vivo high-efficiency transcoronary gene delivery and Cre–LoxP gene switching in the adult mouse heart

J. Ross, Yusu Gu, K. Chien, 2003, Gene Therapy.

Gene transfer of a phospholamban-targeted antibody improves calcium handling and cardiac function in heart failure.

J. Ross, Yusu Gu, K. Peterson, 2005, Cardiovascular research.

Coxsackievirus and adenovirus receptor (CAR) mediates atrioventricular-node function and connexin 45 localization in the murine heart.

A. McCulloch, Yusu Gu, N. Dalton, 2008, The Journal of clinical investigation.

Selective deletion of long but not short Cypher isoforms leads to late-onset dilated cardiomyopathy.

Yusu Gu, N. Dalton, K. Peterson, 2011, Human molecular genetics.

Mouse and computational models link Mlc2v dephosphorylation to altered myosin kinetics in early cardiac disease.

A. McCulloch, Yusu Gu, N. Dalton, 2012, The Journal of clinical investigation.

Heart Failure Absence of Socs3 in the Cardiomyocyte Increases Mortality in a Gp130-dependent Manner Accompanied by Contractile Dysfunction and Ventricular Arrhythmias Clinical Perspective on P 2701

Yusu Gu, N. Dalton, T. Yajima, 2022 .

Desmosomal junctions are necessary for adult sinus node function.

A. McCulloch, Yusu Gu, N. Dalton, 2016, Cardiovascular research.

Tbx20 regulates a genetic program essential to adult mouse cardiomyocyte function.

G. Wang, John M Westlund, Yusu Gu, 2011, The Journal of clinical investigation.

Progressive cardiac dysfunction and fibrosis in the cardiomyopathic hamster and effects of growth hormone and angiotensin-converting enzyme inhibition.

J. Ross, Yusu Gu, K. Peterson, 1999, Circulation.

Impaired exercise capacity and skeletal muscle function in a mouse model of pulmonary inflammation.

Yusu Gu, N. Dalton, K. Peterson, 2013, Journal of applied physiology.

Interaction of Filamin C With Actin Is Essential for Cardiac Development and Function

Yusu Gu, S. Ithychanda, Ju Chen, 2023, Circulation research.