H. Husi

发表

The HUPO PSI's Molecular Interaction format—a community standard for the representation of protein interaction data

C. Sander, B. Steipe, P. Bork, 2004, Nature Biotechnology.

Proteomic Analysis of in Vivo Phosphorylated Synaptic Proteins*

Iain D G Campuzano, S. Grant, H. Husi, 2005, Journal of Biological Chemistry.

Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome

S. Grant, H. Husi, Chris N. G. Anderson, 2006, Journal of neurochemistry.

Isolation of 2000‐kDa complexes of N‐methyl‐d‐aspartate receptor and postsynaptic density 95 from mouse brain

S. Grant, H. Husi, 2001, Journal of neurochemistry.

Proteomic analysis of NMDA receptor–adhesion protein signaling complexes

S. Grant, H. Husi, J. Choudhary, 2000, Nature Neuroscience.

Proteomics and Metabolomics for AKI Diagnosis.

H. Husi, M. Klingele, J. Zoidakis, 2018, Seminars in nephrology.

Protein Interactome of Muscle Invasive Bladder Cancer

A. Vlahou, H. Husi, A. Heinzel, 2015, PloS one.

New insights in molecular mechanisms involved in chronic kidney disease using high-resolution plasma proteome analysis.

A. Vlahou, H. Husi, H. Mischak, 2015, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Omics databases on kidney disease: where they can be found and how to benefit from them

H. Husi, R. Stevens, J. Schanstra, 2016, Clinical kidney journal.

Classical MALDI-MS versus CE-based ESI-MS proteomic profiling in urine for clinical applications.

H. Husi, H. Mischak, J. Schanstra, 2014, Bioanalysis.

Selective chemical intervention in the proteome of Caenorhabditis elegans.

H. Husi, N. Angelopoulos, Victoria J. Butler, 2010, Journal of proteome research.

The Organization and Integrative Function of the Post-Synaptic Proteome

S. Grant, H. Husi, Mark Cumiskey, 2003 .

Urinary peptidomics analysis reveals proteases involved in diabetic nephropathy

A. Vlahou, H. Husi, H. Mischak, 2017, Scientific Reports.

Systems Biology Approach in Hypertension Research.

H. Husi, C. Delles, 2017, Methods in molecular biology.

Isotopically labeled bovine beta-lactoglobulin for NMR studies expressed in Pichia pastoris.

H. Husi, C. Batt, D. Uhrín, 1998, Protein expression and purification.

Proteome-Based Systems Biology Analysis of the Diabetic Mouse Aorta Reveals Major Changes in Fatty Acid Biosynthesis as Potential Hallmark in Diabetes Mellitus–Associated Vascular Disease

A. Vlahou, H. Husi, H. Mischak, 2014, Circulation. Cardiovascular genetics.

The Human Urinary Proteome Fingerprint Database UPdb

H. Husi, J. Ross, C. Greig, 2013, International journal of proteomics.

Establishment of a integrative multi-omics expression database CKDdb in the context of chronic kidney disease (CKD)

H. Husi, Marco Fernandes, 2017, Scientific Reports.

The influence of hypoxia on the prostate cancer proteome

H. Husi, J. Ross, F. Habib, 2020, Clinical chemistry and laboratory medicine.

Proteomic identification of potential cancer markers in human urine using subtractive analysis.

H. Husi, J. Ross, R. Skipworth, 2016, International journal of oncology.

Proteomics in the Neurosciences

S. Grant, H. Husi, M. Collins, 2004 .

Acute kidney injury prediction in cardiac surgery patients by a urinary peptide pattern: a case-control validation study

H. Husi, M. Klingele, H. Mischak, 2016, Critical Care.

Separation of human vitamin K-dependent coagulation proteins using hydrophobic interaction chromatography.

H. Husi, M. Walkinshaw, 1999, Journal of chromatography. B, Biomedical sciences and applications.

degradation in adult rat diaphragm muscle The effect of denervation on protein synthesis and

H. Husi, Pham Nguyen Quy, C. Greig, 2015 .

Mapping of the immunophilin-immunosuppressant site of interaction on calcineurin.

H. Husi, M. Zurini, M. Luyten, 1994, The Journal of biological chemistry.

Gene Ontology (GO)-Driven Inference of Candidate Proteomic Markers Associated with Muscle Atrophy Conditions

H. Husi, A. Stalmach, R. Skipworth, 2022, Molecules.

Tissue Proteomics in Vascular Disease.

H. Husi, H. Mischak, W. Mullen, 2017, Methods in molecular biology.

Identification of diagnostic upper gastrointestinal cancer tissue type-specific urinary biomarkers

H. Husi, J. Ross, R. Skipworth, 2019, Biomedical reports.

The X‐ray structure of a divergent cyclophilin from the nematode parasite Brugia malayi

H. Husi, P. Taylor, M. Walkinshaw, 1998, FEBS letters.

The Many Facets of Fabry Disease in the Kidney-Heart Axis

H. Husi, Marco Fernandes, 2018 .

Integrative Systems Biology Investigation of Fabry Disease

H. Husi, Marco Fernandes, 2016, Diseases.

Covalent binding of cyclosporine inhibits irreversibly T-lymphocyte activation.

H. Husi, B. Ryffel, B. Foxwell, 1992, Biochemical pharmacology.

Identification of several cyclosporine binding proteins in lymphoid and non-lymphoid cells in vivo.

H. Husi, B. Ryffel, B. Foxwell, 1992, Biochimica et biophysica acta.

Identification of PSD-93 as a Substrate for the Src Family Tyrosine Kinase Fyn*

S. Grant, H. Husi, T. Akiyama, 2003, Journal of Biological Chemistry.

Immunological Techniques to Assess Protein Thiol Redox State: Opportunities, Challenges and Solutions

H. Husi, J. Cobley, 2020, Antioxidants.

Assessment of Metabolomic and Proteomic Biomarkers in Detection and Prognosis of Progression of Renal Function in Chronic Kidney Disease

Julie Klein, Holger Husi, Harald Mischak, 2014, PloS one.

Proteomics of multiprotein complexes: answering fundamental questions in neuroscience.

S. Grant, H. Husi, 2001, Trends in biotechnology.

Bile and urine peptide marker profiles: access keys to molecular pathways and biological processes in cholangiocarcinoma

M. Manns, H. Husi, H. Mischak, 2020, Journal of Biomedical Science.

Structures of cyclophilin-ligand complexes.

H. Husi, P. Taylor, M. Walkinshaw, 1997, Progress in biophysics and molecular biology.

CVD and Oxidative Stress

H. Husi, D. Llanas-Cornejo, Karla I Cervantes Gracia, 2017, Journal of clinical medicine.

Proteomics and Metabolomics for AKI Diagnosis.

H. Husi, M. Klingele, J. Zoidakis, 2018, Seminars in nephrology.

Current advances in systems and integrative biology

Holger Husi, Marco Fernandes, Scott W. Robinson, 2014, Computational and structural biotechnology journal.

Biochemical and Structural Characterization of a Divergent Loop Cyclophilin from Caenorhabditis elegans *

H. Husi, Su-Ying Wu, P. Taylor, 1999, The Journal of Biological Chemistry.

Neuropathic Sensitization of Behavioral Reflexes and Spinal NMDA Receptor/CaM Kinase II Interactions Are Disrupted in PSD-95 Mutant Mice

S. Grant, H. Husi, S. Fleetwood-Walker, 2003, Current Biology.

Proteomic strategies to unravel age‐related redox signalling defects in skeletal muscle

H. Husi, J. Cobley, B. McDonagh, 2019, Free radical biology & medicine.

Chapter 9 – Proteomics

Amaya Albalat, Holger Husi, H. Husi, 2014 .

Purification of factor X by hydrophobic interaction chromatography.

H. Husi, M. Walkinshaw, 2001, Journal of chromatography. B, Biomedical sciences and applications.

A combinatorial approach of Proteomics and Systems Biology in unravelling the mechanisms of acute kidney injury (AKI): involvement of NMDA receptor GRIN1 in murine AKI

Alberto Ortiz, Holger Husi, Harald Mischak, 2013, BMC Systems Biology.

Urinary diagnostic proteomic markers for dynapenia in cancer patients.

H. Husi, J. Ross, C. Greig, 2018, Biomedical reports.

Proteomics of Vitreous Humor of Patients with Exudative Age-Related Macular Degeneration

H. Husi, H. Mischak, J. Jankowski, 2014, PloS one.

Reversible Thiol Oxidation Inhibits the Mitochondrial ATP Synthase in Xenopus laevis Oocytes

H. Husi, Rachel Bessell, J. Cobley, 2020, Antioxidants.

Catalyst-free Click PEGylation reveals substantial mitochondrial ATP synthase sub-unit alpha oxidation before and after fertilisation

H. Husi, J. Cobley, M. Guille, 2019, Redox biology.

Molecular determinants of acute kidney injury

H. Husi, C. Human, 2015, Journal of injury & violence research.

Robust Enrichment of Phosphorylated Species in Complex Mixtures by Sequential Protein and Peptide Metal-Affinity Chromatography and Analysis by Tandem Mass Spectrometry

S. Grant, H. Husi, M. Collins, 2005, Science's STKE.

Computational Approaches in Proteomics

H. Husi, K. Gracia, Karla I Cervantes Gracia, 2019, Computational Biology.

Identification of diagnostic upper gastrointestinal cancer tissue type-specific urinary biomarkers

H. Husi, J. Ross, R. Skipworth, 2019, Biomedical reports.

Programmed cell death 6 interacting protein (PDCD6IP) and Rabenosyn‐5 (ZFYVE20) are potential urinary biomarkers for upper gastrointestinal cancer

H. Husi, J. Ross, C. Greig, 2015, Proteomics. Clinical applications.

Integrative Systems Biology Resources and Approaches in Disease Analytics

Holger Husi, Marco Fernandes, H. Husi, 2019, Systems Biology.

Commentary: Integrative Analysis of Multiple Sclerosis Using a Systems Biology Approach

H. Husi, Monterrey, Karla Gracia, 2018, Journal of Neurology & Neuromedicine.

HabitualMyo fi brillarProteinSynthesis IsNormal in Patients with Upper GI Cancer Cachexia

H. Husi, J. Ross, C. Greig, 2015 .

Habitual Myofibrillar Protein Synthesis Is Normal in Patients with Upper GI Cancer Cachexia

H. Husi, J. Ross, C. Greig, 2014, Clinical Cancer Research.

Mitogen-Activated Protein Kinase 14 Promotes AKI.

H. Husi, M. Sánchez-Niño, H. Mischak, 2017, Journal of the American Society of Nephrology : JASN.

Molecular Model for CKD

Marco Fernandes, Katryna Cisek, Holger Husi, 2018 .

Diagnosis and Prediction of CKD Progression by Assessment of Urinary Peptides.

A. Vlahou, H. Husi, J. Staessen, 2015, Journal of the American Society of Nephrology : JASN.

NMDA receptors, neural pathways, and protein interaction databases.

H. Husi, 2004, International review of neurobiology.

Improving peptide relative quantification in MALDI‐TOF MS for biomarker assessment

A. Vlahou, H. Husi, H. Mischak, 2013, Proteomics.

C/VDdb: A multi-omics expression profiling database for a knowledge-driven approach in cardiovascular disease (CVD)

Holger Husi, Marco Fernandes, Alisha Patel, 2018, bioRxiv.

Increased Skeletal Muscle 11βHSD1 mRNA Is Associated with Lower Muscle Strength in Ageing

H. Husi, J. Starr, A. MacLullich, 2013, PloS one.

Integrative OMICS Data-Driven Procedure Using a Derivatized Meta-Analysis Approach

H. Husi, R. Chahwan, Karla Cervantes-Gracia, 2022, Frontiers in Genetics.

Proteomics of the nervous system

Holger Husi, S. Grant, H. Husi, 2001, Trends in Neurosciences.

Knowledge Discovery and Data Mining

Holger Husi, Magdalena Krochmal, H. Husi, 2018 .

Proteomic analysis of urinary upper gastrointestinal cancer markers

H. Husi, J. Ross, C. Greig, 2011, Proteomics. Clinical applications.

Identification of Urinary Peptide Biomarkers Associated with Rheumatoid Arthritis

Julie Klein, Holger Husi, Harald Mischak, 2014, PLoS ONE.

Methods in capillary electrophoresis coupled to mass spectrometry for the identification of clinical proteomic/peptidomic biomarkers in biofluids.

H. Husi, H. Mischak, A. Stalmach, 2015, Methods in molecular biology.

Discovery and validation of urinary biomarkers for detection of renal cell carcinoma.

A. Vlahou, H. Husi, H. Mischak, 2014, Journal of proteomics.

Urinary Peptide Analysis Differentiates Pancreatic Cancer From Chronic Pancreatitis

M. Manns, H. Husi, H. Mischak, 2016, Pancreas.

Development of a MALDI MS‐based platform for early detection of acute kidney injury

H. Husi, W. van Biesen, H. Mischak, 2016, Proteomics. Clinical applications.

Proteomics for rejection diagnosis in renal transplant patients: Where are we now?

H. Husi, D. Marx, J. Metzger, 2016, World journal of transplantation.

Proteomics in Kidney Allograft Transplantation—Application of Molecular Pathway Analysis for Kidney Allograft Disease Phenotypic Biomarker Selection

H. Husi, W. Mullen, D. Marx, 2019, Proteomics. Clinical applications.

Suppression of Skeletal Muscle Turnover in Cancer Cachexia: Evidence from the Transcriptome in Sequential Human Muscle Biopsies

H. Husi, J. Ross, J. Timmons, 2012, Clinical Cancer Research.

Oxidative stress and inflammation in the development of cardiovascular disease and contrast induced nephropathy

H. Husi, I. Megson, R. Chahwan, 2020 .

Integrative Analysis of Incongruous Cancer Genomics and Proteomics Datasets.

H. Husi, R. Chahwan, Karla Cervantes-Gracia, 2021, Methods in molecular biology.

Proteomic identification of potential markers of myosteatosis in human urine.

H. Husi, J. Ross, R. Skipworth, 2018, Biomedical reports.

A novel oral tracer procedure for measurement of habitual myofibrillar protein synthesis.

H. Husi, C. Greig, N. Stephens, 2013, Rapid communications in mass spectrometry : RCM.

Effects of older age and age of asthma onset on clinical and inflammatory variables in severe refractory asthma.

N. Thomson, H. Husi, C. Brightling, 2016, Respiratory medicine.

How close are we to finding noninvasive markers for upper GI tract cancer?

H. Husi, J. Ross, R. Skipworth, 2011, Future oncology.

K 14 promotes acute kidney injury

H. Husi, M. Sánchez-Niño, H. Mischak, 2016 .

An improved understanding of pathogenic pathways may identify novel acute kidney injury

H. Husi, M. Sánchez-Niño, H. Mischak, 2016 .

Cerebrospinal fluid prohormone processing and neuropeptides stimulating feed intake of dairy cows during early lactation.

H. Husi, B. Kuhla, W. Mullen, 2015, Journal of proteome research.

MAGE genes in the kidney: identification of MAGED2 as upregulated during kidney injury and in stressed tubular cells.

H. Husi, M. Sánchez-Niño, H. Mischak, 2018, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Performance benchmarking microplate-immunoassays for quantifying target-specific cysteine oxidation reveals their potential for understanding redox-regulation and oxidative stress.

H. Husi, J. Cobley, D. Muggeridge, 2023, Free radical biology & medicine.

Increased sputum endotoxin levels are associated with an impaired lung function response to oral steroids in asthmatic patients.

N. Thomson, H. Husi, R. Chaudhuri, 2014, The Journal of allergy and clinical immunology.

Can a simple proteomics urine test assist in the early diagnosis of early-stage cancer?

H. Husi, J. Ross, K. Fearon, 2011, Expert review of proteomics.

Cheminformatics and Computational Approaches in Metabolomics

Holger Husi, Marco Fernandes, Bela Sanches, 2019, Computational Biology.

Bile and urine peptide marker profiles: access keys to molecular pathways and biological processes in cholangiocarcinoma

M. Manns, H. Husi, H. Mischak, 2020, Journal of Biomedical Science.

Database Creation and Utility

Holger Husi, Magdalena Krochmal, Katryna Cisek, 2018 .