P. Marynen

发表

Gene prioritization through genomic data fusion

Bassem A. Hassan, B. Moor, P. Carmeliet, 2006, Nature Biotechnology.

Allele-specific copy number analysis of tumors

C. Perou, A. Børresen-Dale, A. Zetterberg, 2010, Proceedings of the National Academy of Sciences.

Molecular Karyotyping: Array CGH Quality Criteria for Constitutional Genetic Diagnosis

Bart De Moor, Frank Speleman, Björn Menten, 2005, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

T cell antigen receptor stimulation induces MALT1 paracaspase–mediated cleavage of the NF-κB inhibitor A20

P. Marynen, Zhijian J. Chen, Lijun Sun, 2008, Nature Immunology.

A20 Negatively Regulates T Cell Receptor Signaling to NF-κB by Cleaving Malt1 Ubiquitin Chains1

P. Marynen, J. Ruland, D. Krappmann, 2009, The Journal of Immunology.

The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa-associated lymphoid tissue lymphomas.

P. Marynen, A. Hagemeijer, C. Wolf‐peeters, 1999, Blood.

A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome.

Peter Marynen, Rafeul Alam, Jan Cools, 2003, The New England journal of medicine.

Rearrangement between the MYH11 gene at 16p13 and D12S158 at 12p13 in a case of acute myeloid leukemia M1 (AML‐M1)

P. Marynen, C. Mecucci, M. Martelli, 1998, Genes, chromosomes & cancer.

Delineation of the critical deletion region for congenital heart defects, on chromosome 8p23.1.

P. Marynen, K. Devriendt, J. Vermeesch, 1999, American journal of human genetics.

A rapid, semiautomated method for apolipoprotein E genotyping.

P. Marynen, J. Cassiman, C. Guo, 1993, PCR methods and applications.

TP53 mutations are frequent in malignant NFI tumors

P. Marynen, T. Glover, R. Wu, 1994, Genes, chromosomes & cancer.

cIAP2 is a ubiquitin protein ligase for BCL10 and is dysregulated in mucosa-associated lymphoid tissue lymphomas.

Sun-Mi Park, P. Marynen, Xiaolu Yang, 2005, The Journal of clinical investigation.

FIP1L1-PDGFRA in chronic eosinophilic leukemia and BCR-ABL1 in chronic myeloid leukemia affect different leukemic cells

P. Marynen, C. Mecucci, M. Martelli, 2007, Leukemia.

Novel class II HLA-DRB4 and DPB1 alleles found in the Belgian population

P. Marynen, R. Bouillon, J. Cassiman, 2004, Immunogenetics.

Detection of bacterial and mycoplasma contamination in cell cultures by polymerase chain reaction.

P. Marynen, J. Cassiman, M. Spaepen, 1992, FEMS microbiology letters.

Telomere length homeostasis and telomere position effect on a linear human artificial chromosome are dictated by the genetic background

P. Marynen, T. Voet, L. Schoonjans, 2012, Nucleic acids research.

Cellular transformation of NIH3T3 fibroblasts by CIZ/NMP4 fusions

P. Marynen, A. Corveleyn, J. Cools, 2005, Journal of cellular biochemistry.

TEL gene is involved in myelodysplastic syndromes with either the typical t(5;12)(q33;p13) translocation or its variant t(10;12)(q24;p13).

P. Marynen, A. Aventín, C. Mecucci, 1995, Blood.

Molecular cloning of amphiglycan, a novel integral membrane heparan sulfate proteoglycan expressed by epithelial and fibroblastic cells

P. Marynen, J. Cassiman, H. van den Berghe, 1992, The Journal of cell biology.

Loss of SLC38A5 and FTSJ1 at Xp11.23 in three brothers with non-syndromic mental retardation due to a microdeletion in an unstable genomic region

J. Gécz, P. Marynen, H. Ropers, 2007, Human Genetics.

The Dark Side of EGFP: Defective Polyubiquitination

P. Marynen, H. Noels, A. Billiau, 2006, PloS one.

Deletion of the short arm of chromosome 12 is a secondary event in acute lymphoblastic leukemia with t(12;21).

P. Marynen, R. Berger, S. Romana, 1996, Leukemia.

Fusion of a Novel Gene, BTL, to ETV6 in Acute Myeloid Leukemias With a t(4;12)(q11-q12;p13)

P. Marynen, A. Hagemeijer, J. Cools, 1999 .

Fusion of a novel gene, BTL, to ETV6 in acute myeloid leukemias with a t(4;12)(q11-q12;p13).

P. Marynen, A. Hagemeijer, J. Cools, 1999, Blood.

Biallelic alterations of both ETV6 and CDKN1B genes in a t(12;21) childhood acute lymphoblastic leukemia case.

P. Marynen, C. Mecucci, J. Aerssens, 1996, Cancer research.

ETV6 gene rearrangements in hematopoietic malignant disorders.

P. Marynen, C. Mecucci, H. van den Berghe, 1996, Leukemia & lymphoma.

JAK2 rearrangements, including the novel SEC31A-JAK2 fusion, are recurrent in classical Hodgkin lymphoma.

P. Marynen, P. de Paepe, C. de Wolf‐Peeters, 2009, Blood.

JAK 2 rearrangements , including the novel SEC 31 AJAK 2 fusion , are recurrent in classical Hodgkin lymphoma *

P. Marynen, P. D. Paepe, C. Wolf‐peeters, 2011 .

MAPK phosphatase DUSP16/MKP-7, a candidate tumor suppressor for chromosome region 12p12–13, reduces BCR-ABL-induced transformation

P. Marynen, R. Sciot, J. Goris, 2003, Oncogene.

The mitochondrial solute carrier SLC25A5 at Xq24 is a novel candidate gene for non-syndromic intellectual disability

J. Rosenfeld, P. Marynen, K. Devriendt, 2013, Human Genetics.

Detection of genomic copy number changes in patients with idiopathic mental retardation by high‐resolution X‐array‐CGH: important role for increased gene dosage of XLMR genes

P. Marynen, K. Devriendt, J. Vermeesch, 2007, Human mutation.

Mutations in L1-CAM in two families with X linked complicated spastic paraplegia, MASA syndrome, and HSAS.

P. Marynen, J. Fryns, T. Glover, 1995, Journal of medical genetics.

Advances in Brief Prediction of Resistance to Small Molecule FLT 3 Inhibitors : Implications for Molecularly Targeted Therapy of Acute Leukemia

D. Fabbro, P. Marynen, P. Furet, 2004 .

The FIP1L1-PDGFR&agr; kinase in hypereosinophilic syndrome and chronic eosinophilic leukemia

P. Marynen, D. Gilliland, J. Cools, 2004, Current opinion in hematology.

Encephalocraniocutaneous lipomatosis with a mutation in the NF1 gene.

P. Marynen, J. Fryns, E. Legius, 1995, Journal of medical genetics.

Glypican-6, a New Member of the Glypican Family of Cell Surface Heparan Sulfate Proteoglycans*

P. Marynen, J. Vermeesch, H. Ceulemans, 1999, The Journal of Biological Chemistry.

The product of the t(11;18), an API2-MLT fusion, is an almost exclusive finding in marginal zone cell lymphoma of extranodal MALT-type.

P. Marynen, C. Wolf‐Peeters, C. de Wolf‐Peeters, 2000, Annals of oncology : official journal of the European Society for Medical Oncology.

Competitive in situ hybridization in a mediastinal germ cell tumor.

P. Marynen, G. Deneffe, H. van den Berghe, 1994, Cancer genetics and cytogenetics.

Immature teratoma of the pineal gland with isochromosome 12p

H. V. den Berghe, P. Marynen, P. Cin, 1997, Acta Neuropathologica.

Kinase activation and transformation by NUP214-ABL1 is dependent on the context of the nuclear pore.

P. Marynen, M. Fornerod, D. Gilliland, 2008, Molecular cell.

Prognostic significance of lymphocyte morphology in patients with advanced chronic lymphocytic leukemia treated with first line therapy of fludarabine + prednisone.

P. Marynen, C. Mecucci, M. Martelli, 1994 .

Intestinal neurofibromatosis is a subtype of familial GIST and results from a dominant activating mutation in PDGFRA.

P. Marynen, R. Sciot, M. Debiec‐Rychter, 2006, Gastroenterology.

Primary structure of pregnancy zone protein. Molecular cloning of a full-length PZP cDNA clone by the polymerase chain reaction.

P. Marynen, K. Devriendt, J. Cassiman, 1991, Biochimica et Biophysica Acta.

A genetic polymorphism in a functional domain of human pregnancy zone protein: the bait region

P. Marynen, K. Devriendt, J. Cassiman, 1990, FEBS letters.

Role of the alpha 2M-receptor in attachment and spreading of human fibroblasts.

P. Marynen, F. van Leuven, J. Cassiman, 1981, Cell biology international reports.

Inhibition of intracellular proteolytic processing of soluble proproteins by an engineered alpha 2-macroglobulin containing a furin recognition sequence in the bait region.

P. Marynen, W. V. D. Van de Ven, T. Ayoubi, 1997, The Biochemical journal.

Efficient male and female germline transmission of a human chromosomal vector in mice.

P. Marynen, J. Vermeesch, T. Voet, 2001, Genome research.

Evidence for position effects as a variant ETV6-mediated leukemogenic mechanism in myeloid leukemias with a t(4;12)(q11-q12;p13) or t(5;12)(q31;p13).

P. Marynen, A. Hagemeijer, M. Odero, 2002, Blood.

The EOL-1 cell line as an in vitro model for the study of FIP1L1-PDGFRA-positive chronic eosinophilic leukemia.

P. Marynen, H. Drexler, J. Griffin, 2004, Blood.

MALT1 Auto-Proteolysis Is Essential for NF-κB-Dependent Gene Transcription in Activated Lymphocytes

P. Marynen, M. Thome, M. Baens, 2014, PloS one.

Auto-Ubiquitination-Induced Degradation of MALT1-API2 Prevents BCL10 Destabilization in t(11;18)(q21;q21)-Positive MALT Lymphoma

P. Marynen, H. Noels, C. de Wolf‐Peeters, 2009, PloS one.

A Novel TRAF6 Binding Site in MALT1 Defines Distinct Mechanisms of NF-κB Activation by API2·MALT1 Fusions*

P. Marynen, H. Noels, G. van Loo, 2007, Journal of Biological Chemistry.

Selective Expansion of Marginal Zone B Cells in Eμ-API2-MALT1 Mice Is Linked to Enhanced IκB Kinase γ Polyubiquitination

P. Marynen, H. Noels, C. Wolf‐peeters, 2006 .

MALT1 is deregulated by both chromosomal translocation and amplification in B-cell non-Hodgkin lymphoma.

Peter Marynen, Reiner Siebert, Randy D Gascoyne, 2003, Blood.

Comparative expressed sequence hybridization studies of t(11;18)(q21;q21)-positive and -negative gastric MALT lymphomas reveal both unique and overlapping gene programs

P. Loo, P. Marynen, C. Wolf‐peeters, 2010, Modern Pathology.

Detection of t(11;18)(q21;q21) by interphase fluorescence in situ hybridization using API2 and MLT specific probes.

P. Gaulard, P. Marynen, A. Hagemeijer, 2000, Blood.

Inv(2)(p23q35) in anaplastic large-cell lymphoma induces constitutive anaplastic lymphoma kinase (ALK) tyrosine kinase activation by fusion to ATIC, an enzyme involved in purine nucleotide biosynthesis.

R. Siebert, P. Marynen, C. Wolf‐peeters, 2000, Blood.

A 4-Mb BAC/PAC contig and complete genomic structure of the GPC5/GPC6 gene cluster on chromosome 13q32.

P. Marynen, J. Vermeesch, J. Fryns, 2001, Matrix biology : journal of the International Society for Matrix Biology.

Polymorphous endocytotic organelles in the receptor-mediated endocytosis of gold-labelled alpha 2-macroglobulin complexes by human fibroblasts.

P. Marynen, F. van Leuven, J. Cassiman, 1985, Journal of cell science.

Evidence for increased SOX3 dosage as a risk factor for X‐linked hypopituitarism and neural tube defects

P. Marynen, H. Van Esch, J. Fryns, 2014, American journal of medical genetics. Part A.

ALK‐ATIC fusion in urinary bladder inflammatory myofibroblastic tumor

P. Marynen, A. Hagemeijer, P. Pauwels, 2003, Genes, chromosomes & cancer.

Identification of Intellectual Disability Genes in Female Patients with a Skewed X‐Inactivation Pattern

J. Lupski, R. Gibbs, D. Muzny, 2016, Human mutation.

Myeloid cell diff erentiation arrest by miR-125b-1 in myelodysplasic syndrome and acute myeloid leukemia with the t(2;11)(p21;q23) translocation Most chromosomal translocations in myelodysplastic syndromes (MDS)

P. Brousset, P. Marynen, A. Hagemeijer, 2008 .

Copy-number gains of HUWE1 due to replication- and recombination-based rearrangements.

P. Marynen, T. Bose, M. Roselló, 2012, American journal of human genetics.

Human and rat chromosomal localization of two genes for 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase by analysis of somatic cell hybrids and in situ hybridization.

P. Marynen, M. Chikri, G. Rousseau, 1991, Genomics.

Characterization of a helicase-like transcription factor involved in the expression of the human plasminogen activator inhibitor-1 gene.

L. Nelles, P. Marynen, M. Carmo-Fonseca, 1996, DNA and cell biology.

Spatial and temporal changes in the expression of fibroglycan (syndecan-2) during mouse embryonic development.

P. Marynen, X. Bai, J. Cassiman, 1993, Development.

Localization of the gene encoding the α2 subunit of the human VLA-2 receptor to chromosome 5q23-31

P. Marynen, J. Cassiman, H. Cuppens, 1991 .

Report of the fourth International Workshop in Human Chromosome 12 Mapping, 1997.

R. Kucherlapati, P. Marynen, C. Turc‐Carel, 1997, Cytogenetics and cell genetics.

Report of the Third International Workshop on Human Chromosome 12 Mapping 1995.

R. Kucherlapati, P. Marynen, 1996, Cytogenetics and cell genetics.

Sorafenib is a potent inhibitor of FIP1L1-PDGFRalpha and the imatinib-resistant FIP1L1-PDGFRalpha T674I mutant.

P. Marynen, J. Cools, N. Mentens, 2006, Blood.

Sorafenib (BAY43-9006) is a potent inhibitor of FIP1L1-PDGFR α and the imatinib resistant FIP1L1-PDGFR α T674I mutant

P. Marynen, J. Cools, N. Mentens, 2006 .

Novel PORCN mutations in focal dermal hypoplasia

P. Marynen, K. Devriendt, H. Van Esch, 2009, Clinical genetics.

Primary Structure and Gene Structure of Staphylokinase

P. Marynen, P. Holvoet, D. Collen, 1992 .

A cluster of α2-macroglobulin-related genes (α2M) on human chromosome 12p: cloning of the pregnancy-zone protein gene and an α2M pseudogene

P. Marynen, K. Devriendt, J. Cassiman, 1989 .

Identification of internal variation in the pseudoautosomal VNTR DXYS17, with nonrandom distribution of the alleles on the X and the Y chromosomes.

P. Marynen, R. Decorte, J. Cassiman, 1994, American journal of human genetics.

Telomere-independent homologue pairing and checkpoint escape of accessory ring chromosomes in male mouse meiosis

B. Liebe, H. Scherthan, P. Marynen, 2003, The Journal of cell biology.

The product of the t(11;18), an API2-MLT fusion, marks nearly half of gastric MALT type lymphomas without large cell proliferation.

P. Marynen, C. Wolf‐peeters, C. de Wolf‐Peeters, 2000, The American journal of pathology.

Molecular characterization of 12p abnormalities in hematologic malignancies: deletion of KIP1, rearrangement of TEL, and amplification of CCND2.

P. Marynen, M. Höglund, B. Johansson, 1996, Blood.

Two cases of myeloid disorders and a t(8;12) (q12;p13).

P. Marynen, J. García, N. Gutiérrez, 2000, Haematologica.

Interstitial del(14)(q) involving IGH: a novel recurrent aberration in B-NHL

P. Loo, P. Marynen, J. Vermeesch, 2007, Leukemia.

Fusion of ETV6 to MDS1/EVI1 as a result of t(3;12)(q26;p13) in myeloproliferative disorders.

P. Marynen, A. Hagemeijer, H. van den Berghe, 1997, Cancer research.

Activity of imatinib in systemic mastocytosis with chronic basophilic leukemia and a PRKG2-PDGFRB fusion

P. Marynen, D. Arthur, I. Lahortiga, 2008, Haematologica.

The 12;21 translocation involving TEL and deletion of the other TEL allele: two frequently associated alterations found in childhood acute lymphoblastic leukemia.

P. Marynen, Caiying Guo, H. Cavé, 1996, Blood.

FIP1L1-PDGFRalpha in hypereosinophilic syndrome and mastocytosis.

P. Marynen, J. Cools, G. Gilliland, 2004, The hematology journal : the official journal of the European Haematology Association.

B-cell lymphoma ALK activation by the CLTC-ALK fusion is a recurrent event in large

P. Marynen, F. Speleman, P. D. Paepe, 2013 .

Complex genomic rearrangement of ALK loci associated with integrated human Epstein-Barr virus in a post-transplant myogenic liver tumor.

P. Marynen, A. Hagemeijer, R. Sciot, 2003, The American journal of pathology.

A deletion polymorphism in the human alpha-2-macroglobulin (A2M) gene.

P. Marynen, G. Matthijs, 1991, Nucleic acids research.

Cloning and characterization of the promoter region of the murine alpha-4 integrin subunit.

P. Marynen, G. Matthijs, J. Cassiman, 1994, DNA and cell biology.

Prader-Willi syndrome.

P. Marynen, K. Devriendt, J. Vermeesch, 1998, The American journal of psychiatry.

positive chronic eosinophilic leukemia - The EOL-1 cell line as an in vitro model for the study of FIP1L1-PDGFRA

P. Marynen, H. Drexler, J. Griffin, 2013 .

Hypereosinophilic SyndromeResearch Paper

P. Marynen, A. Aventín, C. Mecucci, 2005 .

Partial primary structure of the 48- and 90-kilodalton core proteins of cell surface-associated heparan sulfate proteoglycans of lung fibroblasts. Prediction of an integral membrane domain and evidence for multiple distinct core proteins at the cell surface of human lung fibroblasts.

P. Marynen, J. Cassiman, J. Cassiman, 1989, The Journal of biological chemistry.

A20 Negatively Regulates T Cell Receptor

P. Marynen, J. Ruland, D. Krappmann, 2009 .

This information is current as Ubiquitin Chains B by Cleaving Malt 1 κ Signaling to NFA 20 Negatively Regulates T Cell Receptor

P. Marynen, J. Ruland, D. Krappmann, 2009 .

Ubiquitin Chains B by Cleaving Malt 1 κ Signaling to NFA 20 Negatively Regulates T Cell Receptor

P. Marynen, J. Ruland, D. Krappmann, 2009 .

Role of cardiac myocyte tissue factor in heart hemostasis

P. Marynen, T. Voet, N. Mackman, 2007, Journal of thrombosis and haemostasis : JTH.

Report of the International Meeting on Chromosome 12 Genes in Cancer.

R. Kucherlapati, P. Marynen, A. Hagemeijer, 1996, Cytogenetics and cell genetics.

A human homologue (BICD1) of the Drosophila bicaudal-D gene.

P. Marynen, M. Baens, Peter Marynen, 1997, Genomics.

Chromosome mapping using polymerase chain reaction on somatic cell hybrids.

P. Marynen, K. Devriendt, J. Cassiman, 1990, Cancer genetics and cytogenetics.

Submicroscopic duplications of the hydroxysteroid dehydrogenase HSD17B10 and the E3 ubiquitin ligase HUWE1 are associated with mental retardation.

Peter Marynen, Rodney Scott, Patrick S Tarpey, 2008, American journal of human genetics.

Co‐amplification of the cystic fibrosis ΔF508 mutation with the HLA DQA1 sequence in single cell PCR: Implications for improved assessment of polar bodies and blastomeres in preimplantation diagnosis

P. Marynen, R. Decorte, R. Wu, 1993, Prenatal diagnosis.

BIRC3 (baculoviral IAP repeat-containing 3)

P. Marynen, B. Mathijs, 2011 .

MALT1 (mucosa associated lymphoid tissue lymphoma translocation gene 1)

P. Marynen, B. Mathijs, 2011 .

Splenic marginal zone lymphoma-like features in API2-MALT1 transgenic mice that are exposed to antigenic stimulation.

P. Marynen, T. Theys, C. de Wolf‐Peeters, 2006, Haematologica.

The novel t(11;12;18)(q21;q13;q21) represents a variant translocation of the t(11;18)(q21;q21) associated with MALT-type lymphoma

P. Marynen, J. Dierlamm, L. Michaux, 2002, Leukemia.

Translocation t(11;18) absent in early gastric marginal zone B-cell lymphoma of MALT type responding to eradication of Helicobacter pylori infection.

P. Marynen, M. Stolte, J. Dierlamm, 2000, Blood.

The gene for the alpha 4 subunit of the VLA-4 integrin maps to chromosome 2Q31-32.

P. Marynen, J. Cassiman, M. Jaspers, 1991, Blood.

Characterization of 12p molecular events outside ETV6 in complex karyotypes of acute myeloid malignancies

P. Marynen, F. Mandelli, C. Mecucci, 1999, British journal of haematology.

Identification of multiple copies of a 20q-chromosome in a case of myelodysplastic syndrome: a FISH study.

T. L. Hood, P. Marynen, J. Vermeesch, 1999, Leukemia research.

A third MRX family (MRX68) is the result of mutation in the long chain fatty acid-CoA ligase 4 (FACL4) gene: proposal of a rapid enzymatic assay for screening mentally retarded patients

P. Marynen, J. Fryns, M. Raynaud, 2003, Journal of medical genetics.

Sporadic late onset ornithine transcarbamylase deficiency in a boy with somatic mosaicism for an intragenic deletion

P. Marynen, M. Stul, E. Legius, 1990, Clinical genetics.

MCT8 mutation analysis and identification of the first female with Allan–Herndon–Dudley syndrome due to loss of MCT8 expression

J. Gécz, P. Marynen, S. Lenzner, 2008, European Journal of Human Genetics.

Severe alport phenotype in a woman with two missense mutations in the same COL4A5 gene and preponderant inactivation of the X chromosome carrying the normal allele.

P. Marynen, K. Devriendt, J. Cassiman, 1995, The Journal of clinical investigation.

Differential splicing of COL4A5 mRNA in kidney and white blood cells: A complex mutation in the COL4A5 gene of an alport patient deletes the NC1 domain

P. Marynen, J. Cassiman, H. Berghe, 1994, Pediatric Nephrology.

Differential splicing of COL4A5 mRNA in kidney and white blood cells: a complex mutation in the COL4A5 gene of an Alport patient deletes the NC1 domain.

P. Marynen, J. Cassiman, H. Berghe, 1993 .

Submicroscopic deletions in 5 q-associated malignancies

P. Marynen, C. Mecucci, M. Martelli, 2004 .

dup(12)(q13→qter) in two t(14;18)‐negative follicular b‐non‐hodgkin's lymphomas

P. Marynen, C. Mecucci, C. de Wolf‐Peeters, 1992, Genes, chromosomes & cancer.

Genomic organization of TEL: the human ETS-variant gene 6.

P. Marynen, J. Aerssens, M. Baens, 1996, Genome research.

Re-evaluation of MRX36 family after discovery of an ARX gene mutation reveals mild neurological features of Partington syndrome.

P. Marynen, J. Fryns, E. Legius, 2002, American journal of medical genetics.

A new subtype of pre-B acute lymphoblastic leukemia with t(5;12)(q31q33;p12), molecularly and cytogenetically distinct from t(5;12) in chronic myelomonocytic leukemia.

P. Marynen, A. Aventín, C. Mecucci, 1997, Blood.

The Sp1 transcription factor gene (SP1) and the 1,25-dihydroxyvitamin D3 receptor gene (VDR) are colocalized on human chromosome arm 12q and rat chromosome 7.

H. DeLuca, P. Marynen, J. Cassiman, 1991, Genomics.

CREBL2, a novel transcript from the chromosome 12 region flanked by ETV6 and CDKN1B.

P. Marynen, M. Baens, I. Hoornaert, 1998, Genomics.

Assignment of the human glypican gene (GPC1) to 2q35-q37 by fluorescence in situ hybridization.

P. Marynen, J. Vermeesch, G. David, 1995, Genomics.

A new NDE1/PDGFRB fusion transcript underlying chronic myelomonocytic leukaemia in Noonan Syndrome

P. Marynen, C. Mecucci, M. Martelli, 2007, Leukemia.

Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia

Rob Pieters, Frank Speleman, Peter Marynen, 2007, Nature Genetics.

Mapping of structure-function relationships in proteins with a panel of monoclonal antibodies. A study on human alpha 2 macroglobulin.

P. Marynen, F. van Leuven, J. Cassiman, 1988, Journal of immunological methods.

THE MOLECULAR ORGANIZATION OF HUMAN ALPHA 2-MACROGLOBULIN. AN IMMUNO ELECTRON MICROSCOPIC STUDY WITH MONOCLONAL ANTIBODIES

P. Marynen, E. Delain, F. van Leuven, 1988, Thrombosis and Haemostasis.

API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with MALT lymphomas

P. Marynen, J. Dierlamm, I. Wlodarska, 1999 .

Controlled transgene dosage and PAC-mediated transgenesis in mice using a chromosomal vector.

P. Marynen, T. Voet, S. Carpentier, 2003, Genomics.

Germline loss-of-function mutations in SPRED1 cause a neurofibromatosis 1–like phenotype

G. Thomas, P. Marynen, A. Yoshimura, 2007, Nature Genetics.

The ETV6, CDKN1B and D12S178 loci are involved in a segment commonly deleted in various 12p aberration in different hematological malignancies.

P. Marynen, C. Mecucci, H. van den Berghe, 1996, Cytogenetics and cell genetics.

The ability of sorafenib to inhibit oncogenic PDGFRbeta and FLT3 mutants and overcome resistance to other small molecule inhibitors.

P. Marynen, I. Lahortiga, J. Cools, 2007, Haematologica.

Genetic insights in the pathogenesis of T-cell acute lymphoblastic leukemia.

P. Marynen, J. Cools, K. De Keersmaecker, 2005, Haematologica.

Identification of a novel conserved human gene, TEGT.

P. Marynen, L. Walter, G. Levan, 1995, Genomics.

Rapid DNA typing of class II HLA antigens using the polymerase chain reaction and reverse dot blot hybridization.

P. Marynen, R. Decorte, J. Cassiman, 1993, Tissue antigens.

The epitopes of two complex-specific monoclonal antibodies, related to the receptor recognition site, map to the COOH-terminal end of human alpha 2-macroglobulin.

P. Marynen, F. van Leuven, J. Cassiman, 1986, The Journal of biological chemistry.

Relation of internal thioesters to conformational change and receptor-recognition site in alpha 2-macroglobulin complexes.

P. Marynen, F. van Leuven, J. Cassiman, 1982, The Biochemical journal.

Stability of metal uncharged ligand complexes in ion exchangers. Part 1.—Quantitative characterization and thermodynamic basis

P. Marynen, A. Maes, A. Cremers, 1977 .

Thermodynamic stability of the ammonium ions of ethylenediamine and histamine in montmorillonite

P. Marynen, A. Maes, A. Cremers, 1978 .

The Ion Exchange Adsorption of Alkylammonium Ions: An Alternative View

P. Marynen, A. Maes, A. Cremers, 1977 .

Ovarian germ cell tumor with chromosome 12 anomaly but without i(12p).

P. Marynen, H. van den Berghe, P. Dal Cin, 1996, Cancer genetics and cytogenetics.

Identification of the critical region of 12p over-representation in testicular germ cell tumors of adolescents and adults

P. Marynen, L. Looijenga, A. Verkerk, 1998, Oncogene.

Isolation and Characterisation of NotI-end Cosmids Mapping to Human Chromosome 12p

P. Marynen, J. Aerssens, M. Baens, 1994 .

Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis.

Sandra A. Moore, S. Gabriel, T. Golub, 2005, Cancer cell.

A new member of the IL-1 receptor family highly expressed in hippocampus and involved in X-linked mental retardation

Lin Jun, Peter Marynen, Mark T. Ross, 1999, Nature Genetics.

Interaction partners for human ZNF384/CIZ/NMP4--zyxin as a mediator for p130CAS signaling?

Peter Marynen, P. Marynen, H. Janssen, 2006, Experimental cell research.

Emerging patterns of cryptic chromosomal imbalance in patients with idiopathic mental retardation and multiple congenital anomalies: a new series of 140 patients and review of published reports

G Mortier, Y Moreau, B De Moor, 2006, Journal of Medical Genetics.

Characterization of the human alpha 2-macroglobulin gene promoter: identification of a novel, triple TRE/RARE/ERE response element.

P. Marynen, G. Matthijs, J. Cassiman, 1994, Biochemical and biophysical research communications.

Incorporation of dITP or 7-deaza dGTP during PCR improves sequencing of the product.

P. Marynen, M. Stul, J. Cassiman, 1993, Nucleic acids research.

Mechanisms of resistance to imatinib mesylate in gastrointestinal stromal tumors and activity of the PKC412 inhibitor against imatinib-resistant mutants.

P. Marynen, A. Hagemeijer, R. Sciot, 2005, Gastroenterology.

Evidence for Co-Evolution between Human MicroRNAs and Alu-Repeats

G. Verbeke, P. Van Loo, P. Marynen, 2009, PloS one.

X-linked mental retardation and epigenetics

P. Marynen, T. Voet, G. Froyen, 2006, Journal of cellular and molecular medicine.

Recombination hotspot in NF1 microdeletion patients.

M. Dorschner, P. Marynen, C. Lázaro, 2001, Human molecular genetics.

Molecular studies in 20 submicroscopic neurofibromatosis type 1 gene deletions

X. Estivill, P. Marynen, C. Lázaro, 1999, Human mutation.

Efficacy of the Kinase Inhibitor SU11248 against Gastrointestinal Stromal Tumor Mutants Refractory to Imatinib Mesylate

P. Marynen, R. Sciot, M. Debiec‐Rychter, 2006, Clinical Cancer Research.

Acute Lymphoblastic LeukemiaMolecular Basis of Disease

P. Marynen, J. Cools, K. D. Keersmaecker, 2005 .

Molecular cloning of a phosphatidylinositol-anchored membrane heparan sulfate proteoglycan from human lung fibroblasts

P. Marynen, J. Cassiman, H. van den Berghe, 1990, The Journal of cell biology.

Duplication of the MECP2 region is a frequent cause of severe mental retardation and progressive neurological symptoms in males.

J. Gécz, P. Marynen, H. Van Esch, 2005, American journal of human genetics.

Microdissection and FISH investigations in acute myeloid leukemia: a step forward to full identification of complex karyotypic changes.

P. Marynen, J. Vermeesch, C. Mecucci, 2000, Cancer genetics and cytogenetics.

Xp22.3; Yq11.2 chromosome translocation and its clinical manifestations.

L. Lagae, P. Marynen, K. Devriendt, 2001, Annales de genetique.

Malt1 self‐cleavage is critical for regulatory T cell homeostasis and anti‐tumor immunity in mice

P. Marynen, J. Cools, C. D. de Bock, 2018, European journal of immunology.

Small chromosomal regions position themselves autonomously according to their chromatin class.

Wouter Meuleman, Ludo Pagie, Peter Marynen, 2017, Genome research.

Genomic imbalances including amplification of the tyrosine kinase gene JAK2 in CD30+ Hodgkin cells.

P. Marynen, P. Lichter, M. Pfreundschuh, 2000, Cancer research.

Genomic gain at 6p21: a new cryptic molecular rearrangement in secondary myelodysplastic syndrome and acute myeloid leukemia

P. Marynen, A. Aventín, C. Mecucci, 2006, Leukemia.

A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias

P. Marynen, F. Speleman, J. Vandesompele, 2005, Leukemia.

Myeloid cell differentiation arrest by miR-125b-1 in myelodysplasic syndrome and acute myeloid leukemia with the t(2;11)(p21;q23) translocation

Dominique Leroux, Peter Marynen, Eric Lippert, 2008, The Journal of experimental medicine.

X‐linked mental retardation: vanishing boundaries between non‐specific (MRX) and syndromic (MRXS) forms

P. Marynen, S. Frints, J. Fryns, 2002, Clinical genetics.

Translocation t(1;6)(p35.3;p25.2): a new recurrent aberration in ‘unmutated’ B-CLL

P. Marynen, A. Hagemeijer, M. Stul, 2005, Leukemia.

SSCP: a tool for contig building of duplicated genomic regions

P. Marynen, J. Vermeesch, C. López-Correa, 2000 .

Importance of HLA-DRB1 and DQA1 genes and of the amino acid polymorphisms in the functional domain of DRβ1 chain in multiple sclerosis

P. Marynen, J. Cassiman, C. Vandevyver, 1995, Journal of Neuroimmunology.

Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia

A. Ferrando, D. Gilliland, A. Look, 2004, Nature Genetics.

A physical map of the chromosome 12 centromere

P. Marynen, J. Vermeesch, J. Fryns, 2004, Cytogenetic and Genome Research.

NUP214-ABL1 amplification in t(5;14)/HOX11L2-positive ALL present with several forms and may have a prognostic significance

P. Marynen, R. Berger, O. Bernard, 2005, Leukemia.

The IL-9 receptor gene, located in the Xq/Yq pseudoautosomal region, has an autosomal origin, escapes X inactivation and is expressed from the Y.

P. Marynen, J. Vermeesch, J. Renauld, 1997, Human molecular genetics.

Interstitial telomeric sequences at the junction site of a jumping translocation

P. Marynen, K. Devriendt, F. Speleman, 1997, Human Genetics.

Computational methods for the detection of cis-regulatory modules

Peter Van Loo, Peter Marynen, P. Loo, 2009, Briefings Bioinform..

ModuleMiner - improved computational detection of cis-regulatory modules: are there different modes of gene regulation in embryonic development and adult tissues?

Yves Moreau, Stein Aerts, Bart De Moor, 2008, Genome Biology.

A physical, transcript, and deletion map of chromosome region 12p12.3 flanked by ETV6 and CDKN1B: hypermethylation of the LRP6 CpG island in two leukemia patients with hemizygous del(12p).

P. Marynen, A. Hagemeijer, A. Corveleyn, 1999, Genomics.

Resistance to tyrosine kinase inhibitors: calling on extra forces.

P. Marynen, J. Cools, C. Maertens, 2005, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

Characterization of a double homeodomain protein (DUX1) encoded by a cDNA homologous to 3.3 kb dispersed repeated elements.

P. Marynen, H. Ding, D. Collen, 1998, Human molecular genetics.

Nonrecurrent MECP2 duplications mediated by genomic architecture-driven DNA breaks and break-induced replication repair.

P. Marynen, R. Stevenson, C. Schwartz, 2008, Genome research.

Unequal meiotic crossover: a frequent cause of NF1 microdeletions.

P. Marynen, C. Lázaro, E. Legius, 2000, American journal of human genetics.

Genomic organization and evolution of the NF1 microdeletion region.

P. Marynen, J. Vermeesch, C. López-Correa, 2004, Genomics.

The genes coding for rat cystatin-related prostate protein (Cstrp) map to chromosome 3q41.

P. Marynen, J. Cassiman, M. Rivière, 1995, Cytogenetics and cell genetics.

A child, homozygous for a stop codon in exon 11, shows milder cystic fibrosis symptoms than her heterozygous nephew

P. Marynen, J. Cassiman, H. Berghe, 1990, Journal of medical genetics.

Rapid and simple detection of minisatellite regions in forensic DNA samples by the polymerase chain reaction combined with a chemiluminescence method.

P. Marynen, R. Decorte, J. Cassiman, 1990, Trends in genetics : TIG.

Rapid detection of hypervariable regions by the polymerase chain reaction technique.

P. Marynen, R. Decorte, J. Cassiman, 1990, DNA and cell biology.

Eighth International Workshop on Human Gene Mapping

K. O. Elliston, D. Cox, K. Kidd, 1984 .

X chromosome array-CGH for the identification of novel X-linked mental retardation genes.

P. Marynen, H. Van Esch, G. Froyen, 2005, European journal of medical genetics.

Activation of FIP1L1-PDGFRα requires disruption of the juxtamembrane domain of PDGFRα and is FIP1L1-independent

P. Marynen, D. Gilliland, J. Cools, 2006 .

Clinical and molecular features of FIP1L1-PDFGRA (+) chronic eosinophilic leukemias

D. Gilliland, P. Marynen, M. Herregods, 2004, Leukemia.

A novel cryptic translocation t(12;17)(p13;p12–p13) in a secondary acute myeloid leukemia results in a fusion of the ETV6 gene and the antisense strand of the PER1 gene

Peter Marynen, Jan Cools, P. Marynen, 2003, Genes, chromosomes & cancer.

Transformation of hematopoietic cell lines to growth‐factor independence and induction of a fatal myelo‐ and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes

J. Aster, P. Marynen, M. Tomasson, 1998, The EMBO journal.

Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia.

P. Marynen, J. Grosgeorge, J. Cools, 1997, Blood.

Transition from EML1-ABL1 to NUP214-ABL1 positivity in a patient with acute T-lymphoblastic leukemia

P. Marynen, I. Lahortiga, J. Cools, 2006, Leukemia.

Fusion of EML1 to ABL1 in T-cell acute lymphoblastic leukemia with cryptic t(9;14)(q34;q32).

Peter Marynen, Jan Cools, Carlos Graux, 2005, Blood.

e6-a2 BCR-ABL1 fusion in T-cell acute lymphoblastic leukemia

P. Marynen, H. Drexler, H. Quentmeier, 2005, Leukemia.

FOXP1, a gene highly expressed in a subset of diffuse large B-cell lymphoma, is recurrently targeted by genomic aberrations

P. Marynen, A. Hagemeijer, P. D. Paepe, 2005, Leukemia.

Dosage-dependent severity of the phenotype in patients with mental retardation due to a recurrent copy-number gain at Xq28 mediated by an unusual recombination.

P. Marynen, H. Van Esch, C. Spaich, 2009, American journal of human genetics.

Deletion of VCX-A due to NAHR plays a major role in the occurrence of mental retardation in patients with X-linked ichthyosis.

P. Marynen, K. Devriendt, J. Vermeesch, 2005, Human molecular genetics.

Recurrent rearrangement of the Ewing's sarcoma gene, EWSR1, or its homologue, TAF15, with the transcription factor CIZ/NMP4 in acute leukemia.

P. Marynen, A. Hagemeijer, R. Foà, 2002, Cancer research.

Atonal homolog 1 Is a Tumor Suppressor Gene

Bassem A. Hassan, P. Marynen, B. Hassan, 2009, PLoS biology.

Tenth International Workshop on Human Gene Mapping

K. O. Elliston, D. Cox, K. Kidd, 1988 .

Interpretation of the complex karyotype and identification of a new 6p amplicon by integrated comparative genomic hybridization and fluorescence in situ hybridization on the U937-I cell line.

P. Marynen, C. Mecucci, A. Orlacchio, 2002, Cancer Genetics and Cytogenetics.

Fusion of ETV6 to GOT1 in a case with myelodysplastic syndrome and t(10;12)(q24;p13).

P. Marynen, A. Hagemeijer, C. Mecucci, 2006, Haematologica.

Activation of FIP 1 L 1-PDGFR requires disruption of the juxtamembrane domain of PDGFR and is FIP 1 L 1-independent

P. Marynen, D. Gilliland, J. Cools, 2006 .

Fluorescence in situ hybridization characterization of new translocations involving TEL (ETV6) in a wide spectrum of hematologic malignancies.

P. Marynen, A. Hagemeijer, C. Mecucci, 1998, Blood.

Fluorescence in situ hybridization analysis of t(3; 12)(q26; p13): a recurring chromosomal abnormality involving the TEL gene (ETV6) in myelodysplastic syndromes.

P. Marynen, J. Grosgeorge, S. Raynaud, 1996, Blood.

Structure of the MLT gene and molecular characterization of the genomic breakpoint junctions in the t(11;18)(q21;q21) of marginal zone B‐cell lymphomas of MALT type

P. Marynen, C. de Wolf‐Peeters, J. Dierlamm, 2000, Genes, chromosomes & cancer.

Coactivated platelet-derived growth factor receptor {alpha} and epidermal growth factor receptor are potential therapeutic targets in intimal sarcoma.

P. Marynen, R. Sciot, L. Guillou, 2010, Cancer research.

Translocations t(11;18)(q21;q21) and t(14;18)(q32;q21) are the main chromosomal abnormalities involving MLT/MALT1 in MALT lymphomas

C. Copie-Bergman, P. Gaulard, P. Marynen, 2003, Leukemia.

Fusion of EML 1 to ABL 1 in T-cell acute lymphoblastic leukemia with cryptic t ( 9 ; 14 ) ( q 34 ; q 32 )

Peter Marynen, Jan Cools, Carlos Graux, 2005 .

PKC412 overcomes resistance to imatinib in a murine model of FIP1L1-PDGFRα-induced myeloproliferative disease.

D. Fabbro, D. Neuberg, J. Kutok, 2003, Cancer cell.

The NPM-ALK and the ATIC-ALK fusion genes can be detected in non-neoplastic cells.

P. Marynen, C. Wolf‐peeters, C. de Wolf‐Peeters, 2001, The American journal of pathology.

In vitro validation of gamma-secretase inhibitors for the treatment of T-cell acute lymphoblastic leukemia

P. Marynen, I. Lahortiga, J. Cools, 2007 .

GPC4, the gene for human K-glypican, flanks GPC3 on xq26: deletion of the GPC3-GPC4 gene cluster in one family with Simpson-Golabi-Behmel syndrome.

P. Marynen, J. Vermeesch, K. Watanabe, 1998, Genomics.

Evidence for the existence of a pristanoyl-CoA oxidase gene in man.

P. Marynen, G. Mannaerts, P. V. Van Veldhoven, 1997, Biochemical Journal.

Molecular characterization of the human peroxisomal branched-chain acyl-CoA oxidase: cDNA cloning, chromosomal assignment, tissue distribution, and evidence for the absence of the protein in Zellweger syndrome.

J. Leunissen, P. Marynen, J. Vandekerckhove, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Cryptic translocation t(5;18) in familial mental retardation.

P. Marynen, K. Devriendt, J. Vermeesch, 2000, Annales de genetique.

Molecular analysis of the isochromosome 12P in the Pallister-Killian syndrome

P. Marynen, K. Devriendt, J. Fryns, 1989, Human Genetics.

FIP1L1-PDGFRα D842V, a novel panresistant mutant, emerging after treatment of FIP1L1-PDGFRα T674I eosinophilic leukemia with single agent sorafenib

P. Marynen, L. Michaux, J. Cools, 2009, Leukemia.

Conservation of hotspots for recombination in low-copy repeats associated with the NF1 microdeletion

M. Stephens, P. Marynen, C. Lázaro, 2006, Nature Genetics.

architecture-driven DNA breaks and break-induced replication duplications mediated by genomicMECP 2 Nonrecurrent Material Supplemental

P. Marynen, R. Stevenson, C. Schwartz, 2008 .

ALK-positive large B-cell lymphomas with cryptic SEC31A-ALK and NPM1-ALK fusions

J. Delabie, P. Marynen, C. de Wolf‐Peeters, 2010, Haematologica.

The receptor-binding domain of human alpha 2-macroglobulin. Isolation after limited proteolysis with a bacterial proteinase.

P. Marynen, F. van Leuven, J. Cassiman, 1986, The Journal of biological chemistry.

MONOCLONAL ANTIBODIES TOWARD THE RECEPTOR‐RECOGNITION SITE ON α2‐MACROGLOBULIN COMPLEXES a

P. Marynen, J. Cassiman, H. Berghe, 1983 .

Prediction of Resistance to Small Molecule FLT3 Inhibitors

Doriano Fabbro, Peter Marynen, Pascal Furet, 2004, Cancer Research.

De novo MECP2 duplications in two females with intellectual disability and unfavorable complete skewed X-inactivation

S. Seneca, P. Marynen, E. Baere, 2014, Human Genetics.

Generation and Characterization of an Nxf7 Knockout Mouse to Study NXF5 Deficiency in a Patient with Intellectual Disability

R. D'Hooge, P. Marynen, A. Roebroek, 2013, PloS one.

Detection and validation of copy number variation in X-linked mental retardation

P. Marynen, H. Van Esch, H. Esch, 2009, Cytogenetic and Genome Research.

Mild Wolf-Hirschhorn syndrome: micro-array CGH analysis of atypical 4p16.3 deletions enables refinement of the genotype-phenotype map

P. Marynen, T. de Ravel, K. Devriendt, 2004, Journal of Medical Genetics.

Identification of novel fusion partners of ALK, the anaplastic lymphoma kinase, in anaplastic large‐cell lymphoma and inflammatory myofibroblastic tumor

P. Marynen, A. Hagemeijer, P. Pauwels, 2002, Genes, chromosomes & cancer.

Genomic organization of human JAK2 and mutation analysis of its JH2-domain in leukemia

P. Marynen, T. Voet, A. Aventín, 1999, Cytogenetic and Genome Research.

Activation of FIP1L1-PDGFRalpha requires disruption of the juxtamembrane domain of PDGFRalpha and is FIP1L1-independent.

P. Marynen, D. Gilliland, J. Cools, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Submicroscopic deletions in 5q- associated malignancies.

P. Marynen, C. Mecucci, M. Martelli, 2004, Haematologica.

Ubiquitin Ligase HUWE1 Regulates Axon Branching through the Wnt/β-Catenin Pathway in a Drosophila Model for Intellectual Disability

Bassem A. Hassan, Marion Langen, P. Verstreken, 2013, PloS one.

Association between XV2c/CS7/KM19/D9 haplotypes and the ΔF508 mutation A study of 57 Belgian families

P. Marynen, R. Decorte, J. Fryns, 1990, Human Genetics.

Possible association of CD3 and CD4 polymorphisms with insulin‐dependent diabetes mellitus (IDDM)

P. Marynen, R. Decorte, E. Legius, 1994, Clinical and experimental immunology.

The mitochondrial solute carrier SLC25A5 at Xq24 is a novel candidate gene for non-syndromic intellectual disability

J. Rosenfeld, P. Marynen, K. Devriendt, 2013, Human Genetics.

Construction and evaluation of a hncDNA library of human 12p transcribed sequences derived from a somatic cell hybrid.

P. Marynen, J. Cassiman, H. van den Berghe, 1993, Genomics.

A novel fusion of the MALT1 gene and the microtubule‐associated protein 4 (MAP4) gene occurs in diffuse large B‐cell lymphoma

R. Siebert, H. Stein, P. Marynen, 2006, Genes, chromosomes & cancer.

Molecular cytogenetic findings in a four-way t(1;12;5;12)(p36;p13;q33;q24) underlying the ETV6-PDGFRB fusion gene in chronic myelomonocytic leukemia.

P. Marynen, C. Mecucci, M. Martelli, 2007, Cancer genetics and cytogenetics.

The hypereosinophilic syndrome: fluorescence in situ hybridization detects the del(4)(q12)-FIP1L1/PDGFRA but not genomic rearrangements of other tyrosine kinases.

P. Marynen, A. Aventín, C. Mecucci, 2005, Haematologica.

ATIC, an enzyme involved in purine nucleotide biosynthesis anaplastic lymphoma kinase (ALK) tyrosine kinase activation by fusion to Inv(2)(p23q35) in anaplastic large-cell lymphoma induces constitutive

R. Siebert, P. Marynen, S. Gesk, 2013 .

ALK activation by the CLTC-ALK fusion is a recurrent event in large B-cell lymphoma.

P. Marynen, F. Speleman, P. de Paepe, 2003, Blood.

myelodysplastic syndromes in recurring chromosomal abnormality involving the TEL gene (ETV6) Fluorescence in situ hybridization analysis of t(3; 12)(q26; p13): a

P. Marynen, J. Grosgeorge, N. Ayraud, 2011 .

Association of particular HLA class II alleles, haplotypes and genotypes with susceptibility to IDDM in the Belgian population

P. Marynen, L. Sandkuyl, R. Bouillon, 1994, Diabetologia.

Increased and decreased relative risk for noninsulin‐dependent diabetes mellitus conferred by HLA class II and by CD4 alleles

P. Marynen, R. Decorte, E. Legius, 1995, Clinical genetics.

Detection of 98.5% of the mutations in 200 Belgian cystic fibrosis alleles by reverse dot-blot and sequencing of the complete coding region and exon/intron junctions of the CFTR gene.

P. Marynen, J. Cassiman, H. Cuppens, 1993, Genomics.

Activity of Dasatinib, a Dual SRC/ABL Kinase Inhibitor, and IPI-504, a Heat Shock Protein 90 Inhibitor, against Gastrointestinal Stromal Tumor–Associated PDGFRAD842V Mutation

P. Marynen, R. Sciot, M. Debiec‐Rychter, 2008, Clinical Cancer Research.

A Novel TRAF6 binding site in MALT1 defines distinct mechanisms of NF-kappaB activation by API2middle dotMALT1 fusions.

P. Marynen, H. Noels, G. van Loo, 2007, The Journal of biological chemistry.

Molecular Characterization of 12 p Abnormalities in Hematologic Malignancies : Deletion of K I P I , Rearrangement of TEL , and Amplification of CCND 2

P. Marynen, B. Johansson, F. Mitelman, 2002 .

T-cell/histiocyte-rich large B-cell lymphoma shows transcriptional features suggestive of a tolerogenic host immune response

J. Delabie, P. Van Loo, P. Marynen, 2010, Haematologica.

Isolation and regional assignment of human chromosome 12p cDNAs.

P. Marynen, J. Aerssens, H. van den Berghe, 1995, Genomics.

Mapping of an ordered set of 14 cosmids to human chromosome 12p by two-color in situ hybridization.

P. Marynen, J. Aerssens, E. Schoenmakers, 1995, Cytogenetics and cell genetics.

The Atonal Proneural Transcription Factor Links Differentiation and Tumor Formation in Drosophila

Bassem A. Hassan, S. Aerts, P. Marynen, 2009, PLoS Biology.

A monoclonal antibody to a neo-antigen on alpha 2-macroglobulin complexes inhibits receptor-mediated endocytosis.

P. Marynen, F. van Leuven, J. Cassiman, 1981, Journal of immunology.

Multiple small accessory marker chromosomes from different centromeric origin in a moderately mentally retarded male

P. Marynen, J. Vermeesch, J. Fryns, 1999, Human Genetics.

Chromosome healing of constitutional chromosome deletions studied by microdissection

P. Marynen, J. Vermeesch, J. Fryns, 1998, Cytogenetic and Genome Research.

Reversed dot-blotting in hybridoma screening and epitope mapping. A model study with human alpha 2-macroglobulin to select complex-specific monoclonal antibodies.

P. Marynen, F. van Leuven, J. Cassiman, 1986, Journal of immunological methods.

alpha 2-Macroglobulin-proteinase complexes in cystic fibrosis serum. Analysis by monoclonal antibodies and receptor-mediated endocytosis by normal human fibroblasts.

P. Marynen, F. van Leuven, J. Cassiman, 1984, Biochimica et biophysica acta.

DEFECTIVE RECEPTOR BINDING OF NATURALLY OCCURRING α2‐MACROGLOBULIN‐PROTEASE COMPLEXES IN CYSTIC FIBROSIS BY NORMAL HUMAN FIBROBLASTS a

P. Marynen, J. Cassiman, F. Leuven, 1983, Annals of the New York Academy of Sciences.

Solubilization and affinity purification of the alpha 2-macroglobulin receptor from human fibroblasts.

P. Marynen, F. van Leuven, J. Cassiman, 1984, The Journal of biological chemistry.

Human osteosarcoma derived clonal variants: stable differences in cell surface composition.

P. Marynen, F. van Leuven, J. Cassiman, 1982, Cell biology international reports.

Receptor-mediated endocytosis of alpha 2macroglobulin-protease complexes by fibroblasts in culture. Competitive inhibition by bacitracin.

P. Marynen, F. van Leuven, J. Cassiman, 1981, FEBS letters.

Characterization of glypican-5 and chromosomal localization of human GPC5, a new member of the glypican gene family.

P. Marynen, J. Vermeesch, G. Reekmans, 1997, Genomics.

Study of the possible association of HLA class II, CD4, and CD3 polymorphisms with schizophrenia.

P. Marynen, M. De Hert, J. Peuskens, 1994, American journal of medical genetics.

A radiation hybrid map with 60 loci covering the entire short arm of chromosome 12.

P. Marynen, M. Höglund, J. Cassiman, 1995, Genomics.

Selective expansion of marginal zone B cells in Emicro-API2-MALT1 mice is linked to enhanced IkappaB kinase gamma polyubiquitination.

P. Marynen, H. Noels, C. de Wolf‐Peeters, 2006, Cancer research.

NXF5, a novel member of the nuclear RNA export factor family, is lost in a male patient with a syndromic form of mental retardation

P. Marynen, E. Izaurralde, C. Dotti, 2001, Current Biology.

Structural organisation of the gene encoding the α-subunit of the human amiloride-sensitive epithelial sodium channel

P. Marynen, L. Wickert, F. Bidlingmaier, 1998, Human Genetics.

Sorafenib is a potent inhibitor of FIP1L1-PDGFRα and the imatinib-resistant FIP1L1-PDGFRα T674I mutant

P. Marynen, J. Cools, N. Mentens, 2006 .

CALL interrupted in a patient with non-specific mental retardation: gene dosage-dependent alteration of murine brain development and behavior.

R. D'Hooge, P. Marynen, J. Steyaert, 2003, Human molecular genetics.

Mild Wolf-Hirschhorn syndrome: micro-array CGH analysis of atypical 4p16.3 deletions enables refinement of the genotype-phenotype map

P. Marynen, K. Devriendt, J. Vermeesch, 2004, Journal of Medical Genetics.

Breakpoint analysis by fluorescence in situ hybridization in myelodysplastic syndromes with t(3;12)(q26;p13) and expression of EVI1

P. Marynen, K. Kok, E. Vellenga, 2000, Leukemia.

Charge reduction of zeolite Y through exchange with lanthanum ions: Intracrystalline oxide and hydroxide formation

P. Marynen, A. Maes, A. Cremers, 1984 .

Identification of intellectual disability genes in female patients with skewed X-inactivation

S. Seneca, P. Marynen, K. Devriendt, 2015 .

The gene for the peroxisomal targeting signal import receptor (PXR1) is located on human chromosome 12p13, flanked by TPI1 and D12S1089.

P. Marynen, G. Mannaerts, M. Fransen, 1995, Genomics.

Construction of a highly annotated cosmid contig spanning 550Kb within the X-linked nonspecific mental retardation candidate region at Xp21.3-22.1.

J. Weissenbach, T. Bruls, P. Marynen, 1999, American journal of medical genetics.

Linkage analysis in three families with nonspecific X-linked mental retardation.

P. Marynen, S. Claes, J. Fryns, 1996, American journal of medical genetics.

Assignment of the gene for the human proliferating cell nucleolar protein P120 (NOL1) to chromosome 12p13 by fluorescence in situ hybridization and polymerase chain reaction with somatic cell hybrids.

P. Marynen, J. Aerssens, J. Cassiman, 1994, Genomics.

CIZ gene rearrangements in acute leukemia: report of a diagnostic FISH assay and clinical features of nine patients

P. Marynen, A. Hagemeijer, R. Foà, 2005, Leukemia.

Simultaneous screening for 11 mutations in the cystic fibrosis transmembrane conductance regulator gene by multiplex amplification and reverse dot-blot.

P. Marynen, H. Cuppens, I. Buyse, 1992, Molecular and cellular probes.

Inv(X)(p21.1;q22.1) in a man with mental retardation, short stature, general muscle wasting, and facial dysmorphism: Clinical study and mutation analysis of the NXF5 Gene

P. Marynen, K. Devriendt, H. Ropers, 2003, American journal of medical genetics. Part A.

Inv(2)(p23q35) in anaplastic large-cell lymphoma induces constitutive ALK tyrosine kinase activation by fusion to ATIC, an enzyme involved in purine nucleotide biosynthesis

R. Siebert, P. Marynen, S. Gesk, 1999 .

Chromosome abnormalities of the short arm of chromosome 12 in hematopoietic malignancies: a report including three novel translocations involving the TEL/ETV6 gene

P. Marynen, R. Berger, C. Berthou, 1997, Leukemia.

Localisation of a new gene for non-specific mental retardation to Xq22-q26 (MRX35).

P. Marynen, R. Decorte, J. Fryns, 1996, Journal of medical genetics.

AP12-MLT transgenic mice: A model for the pathogenesis of MALT lymphomas?

P. Marynen, C. Wolf‐peeters, X. Sagaert, 2003 .

Nxf7 deficiency impairs social exploration and spatio-cognitive abilities as well as hippocampal synaptic plasticity in mice

R. D'Hooge, P. Marynen, D. Balschun, 2015, Front. Behav. Neurosci..

Limited Expansion of the (CAG)n Repeat of the Huntington Gene: A Premutation (?)

P. Marynen, K. Demyttenaere, R. Dom, 1994, European journal of human genetics : EJHG.

Sorafenib is a potent inhibitor of FIP 1 L 1-PDGFR and the imatinib-resistant FIP 1 L 1-PDGFR T 674 I mutant

P. Marynen, J. Cools, N. Mentens, 2006 .

Molecular cytogenetic and clinical findings in ETV6/ABL1‐positive leukemia

P. Marynen, F. Speleman, A. De Paepe, 2001, Genes, chromosomes & cancer.

In vitro validation of γ-secretase inhibitors alone or in combination with other anti-cancer drugs for the treatment of T-cell acute lymphoblastic leukemia

P. Marynen, M. Odero, L. van Neste, 2008, Haematologica.

Clinical study and haplotype analysis in two brothers with Partington syndrome.

P. Marynen, J. Fryns, G. Froyen, 2002, American journal of medical genetics.

A form of non-specific mental retardation is probably caused by a microdeletion in a Belgian family

P. Marynen, J. Fryns, J. Cassiman, 1996 .

Regional mapping of the human NSP gene to chromosome region 14q21-->q22 by fluorescence in situ hybridization analysis.

P. Marynen, A. Roebroek, W. V. D. Van de Ven, 1994, Cytogenetics and cell genetics.

Structure of the human alpha-2 macroglobulin gene and its promotor.

P. Marynen, K. Devriendt, G. Matthijs, 1992, Biochemical and biophysical research communications.

Differences in the distribution and nature of the interstitial telomeric (TTAGGG)n sequences in the chromosomes of the Giraffidae, okapai (Okapia johnstoni), and giraffe (Giraffa camelopardalis): evidence for ancestral telomeres at the okapi polymorphic rob(5;26) fusion site.

P. Marynen, J. Vermeesch, H. van den Berghe, 1996, Cytogenetics and Cell Genetics.

Genetic heterogeneity in Rieger eye malformation.

P. Marynen, F. Verbraak, R. Decorte, 1994, Journal of medical genetics.

Report and abstracts of the Second International Workshop on Human Chromosome 12 mapping 1994. New Haven, Connecticut, June 20-22, 1994.

R. Kucherlapati, P. Marynen, I. Craig, 1994, Cytogenetics and Cell Genetics.

Identification of a new frameshift mutation and a duplication polymorphism in the CFTR gene in the Algerian population.

P. Marynen, H. Cuppens, J. Cassiman, 1992, Human Molecular Genetics.

Spatial and temporal changes in the expression of fibroglycan (syndecan-2) during mouse embryonic development.

P. Marynen, G. David, Xiao-mei Bai, 1993, Development.

Allele-specific copy number analysis of tumors

C. Perou, A. Børresen-Dale, A. Zetterberg, 2010, Proceedings of the National Academy of Sciences.

European Mathematical Genetics Meeting, Heidelberg, Germany, 12th–13th April 2007

Bassem A. Hassan, B. Moor, P. Carmeliet, 2007 .

A new family of small, palmitoylated, membrane‐associated proteins, characterized by the presence of a cysteine‐rich hydrophobic motif

P. Marynen, J. Cools, N. Mentens, 2001, FEBS letters.

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