K. Brew

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A possible three-dimensional structure of bovine alpha-lactalbumin based on that of hen's egg-white lysozyme.

D. Phillips, A. North, W. J. Browne, 1969, Journal of molecular biology.

Conserved signature proposed for folding in the lipocalin superfamily

Keith Brew, Lesley H Greene, K. Brew, 2003, FEBS letters.

E. coli expression of TIMP-4 and comparative kinetic studies with TIMP-1 and TIMP-2: insights into the interactions of TIMPs and matrix metalloproteinase 2 (gelatinase A).

K. Brew, R. Wait, H. Nagase, 2002, Biochemistry.

Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1

R. Huber, K. Brew, W. Bode, 1997, Nature.

Mutational Study of the Amino-terminal Domain of Human Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) Locates an Inhibitory Region for Matrix Metalloproteinases*

K. Brew, Ko Suzuki, H. Nagase, 1997, The Journal of Biological Chemistry.

Cross-linking of the components of lactose synthetase with dimethylpimelimidate.

K. Brew, R. Hill, K. Olsen, 1975, The Journal of biological chemistry.

Functional site in alpha-lactalbumin encompasses a region corresponding to a subsite in lysozyme and parts of two adjacent flexible substructures.

K. Brew, V. Malinovskii, J. Tian, 1996, Biochemistry.

Characterization of human angiogenin variants implicated in amyotrophic lateral sclerosis.

K. Brew, K. Acharya, R. Shapiro, 2007, Biochemistry.

Urokinase directly activates matrix metalloproteinases-9: a potential role in glioblastoma invasion.

K. Brew, D. Templeton, I. Hussaini, 2008, Biochemical and biophysical research communications.

Role of a conserved acidic cluster in bovine beta1,4 galactosyltransferase-1 probed by mutagenesis of a bacterially expressed recombinant enzyme.

K. Brew, V. Malinovskii, Y. Zhang, 1999, Glycobiology.

Screening a limited structure-based library identifies UDP-GalNAc-specific mutants of alpha-1,3-galactosyltransferase.

Keith Brew, K. Brew, K. Acharya, 2008, Glycobiology.

Structures of Complexes of a Metal-independent Glycosyltransferase GT6 from Bacteroides ovatus with UDP-N-Acetylgalactosamine (UDP-GalNAc) and Its Hydrolysis Products*

K. Brew, M. Lizotte-Waniewski, K. Acharya, 2014, The Journal of Biological Chemistry.

Structure of a metal-independent bacterial glycosyltransferase that catalyzes the synthesis of histo-blood group A antigen

K. Brew, M. Lizotte-Waniewski, K. Acharya, 2012, Scientific Reports.

Secretion of α-Lactalbumin into Milk and its Relevance to the Organization and Control of Lactose Synthetase

K. Brew, 1969, Nature.

Inactivation of N-TIMP-1 by N-terminal acetylation when expressed in bacteria.

K. Brew, S. V. Van Doren, Mark O. Palmier, 2008, Biopolymers.

Structure and function in galactosyltransferase. Sequence locations of alpha-lactalbumin binding site, thiol groups, and disulfide bond.

K. Brew, S. Yadav, 1991, The Journal of biological chemistry.

Sequence homology in the metalloproteins; purple acid phosphatase from beef spleen and uteroferrin from porcine uterus.

J. Yates, K. Brew, J. Shabanowitz, 1987, Biochemical and biophysical research communications.

Composition of the milks of the bottlenose dolphin (Tursiops trucatus) and the Florida manatee (Trichechus manatus latirostris).

K. Brew, S. Pervaiz, Keith Brew, 1986, Comparative biochemistry and physiology. A, Comparative physiology.

Designing TIMP (tissue inhibitor of metalloproteinases) variants that are selective metalloproteinase inhibitors.

K. Brew, H. Nagase, 2003, Biochemical Society symposium.

Primary structural requirements for the enzymatic formation of the N-glycosidic bond in glycoproteins. Studies with alpha-lactalbumin.

K. Brew, W. Lennarz, D. Struck, 1978, The Journal of biological chemistry.

Thermodynamic profiles of the interactions of suramin, chondroitin sulfate, and pentosan polysulfate with the inhibitory domain of TIMP‐3

K. Brew, M. Lizotte-Waniewski, T. Logue, 2020, FEBS letters.

The hormonal control of lactose synthetase in the developing mouse mammary gland.

R. W. Turkington, K. Brew, T. Vanaman, 1968, The Journal of biological chemistry.

Tissue inhibitor of metalloproteinases-1 protects human neurons from staurosporine and HIV-1-induced apoptosis: mechanisms and relevance to HIV-1-associated dementia

Ashutosh, K. Brew, A. Ghorpade, 2012, Cell Death and Disease.

Presence of tear lipocalin and other major proteins in lacrimal fluid of rabbits.

K. Brew, C. Zylberberg, Smitha Kota, 2004, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Characterization of 58-kilodalton human neutrophil collagenase: comparison with human fibroblast collagenase.

K. Brew, H. Birkedal‐Hansen, H. V. Van Wart, 1990, Biochemistry.

Reactive Site Mutations in Tissue Inhibitor of Metalloproteinase-3 Disrupt Inhibition of Matrix Metalloproteinases but Not Tumor Necrosis Factor-α-converting Enzyme*

K. Brew, M. Kashiwagi, Zhihong Xie, 2005, Journal of Biological Chemistry.

Folding and characterization of the amino‐terminal domain of human tissue inhibitor of metalloproteinases‐1 (TIMP‐1) expressed at high yield in E. coli

K. Brew, S. V. Van Doren, Ko Suzuki, 1996, FEBS letters.

Energetics of binding the mammalian high mobility group protein HMGA2 to poly(dA-dT)2 and poly(dA)-poly(dT).

K. Brew, F. Leng, T. Cui, 2005, Journal of molecular biology.

Affinity labeling of bovine colostrum galactosyltransferase with a uridine 5'-diphosphate derivative.

K. Brew, J. Powell, J. Powell, 1976, Biochemistry.

Involvement of tissue inhibitors of metalloproteinases (TIMPS) during matrix metalloproteinase activation.

K. Suzuki, K. Brew, M. Gehring, 1996, Advances in experimental medicine and biology.

Expression of Human Pro-Matrix Metalloproteinase 3 that Lacks the N-terminal 34 Residues in Escherichia coli: Autoactivation and Interaction with Tissue Inhibitor of Metalloproteinase 1 (TIMP-1)

K. Brew, M. Gehring, Ko Suzuki, 1998, Biological chemistry.

A label selection procedure for determining the location of protein-protein interaction sites by cross-linking with bisimidoesters. Application to lactose synthase.

K. Brew, S. Sinha, 1981, Journal of Biological Chemistry.

Isolation of a calcium‐sensitive, 35,000‐dalton microfilament‐ and liposome‐binding protein from ascites tumor cell microvilli: Identification as monomeric calpactin

K. Brew, Y. Liu, C. A. Carraway, 1987, Journal of cellular biochemistry.

Effects of the binding of myosin light chain kinase on the reactivities of calmodulin lysines.

K. Brew, K. Carraway, D. Puett, 1986, Journal of Biological Chemistry.

Effects of Fe3+ binding on the microenvironments of individual amino groups in human serum transferrin as determined by differential kinetic labeling.

K. Brew, J. Shewale, 1982, The Journal of biological chemistry.

Development of a convenient peptide‐based assay for lysyl hydroxylase

K. Brew, G. Fields, M. Cudic, 2008, Biopolymers.

Interaction of human rheumatoid synovial collagenase (matrix metalloproteinase 1) and stromelysin (matrix metalloproteinase 3) with human alpha 2-macroglobulin and chicken ovostatin. Binding kinetics and identification of matrix metalloproteinase cleavage sites.

J. Enghild, K. Brew, G. Salvesen, 1989, The Journal of biological chemistry.

Dm1 and Dm2 Matrix Metallopeptidases

K. Brew, A. Page-McCaw, 2013 .

Identification of a region of UDP-galactose:N-acetylglucosamine beta 4-galactosyltransferase involved in UDP-galactose binding by differential labeling.

K. Brew, S. Yadav, 1990, Journal of Biological Chemistry.

Differentiation of secreted and membrane-type matrix metalloproteinase activities based on substitutions and interruptions of triple-helical sequences.

K. Brew, C. Overall, G. Fields, 2007, Biochemistry.

The Roles of Substrate Thermal Stability and P2 and P1′ Subsite Identity on Matrix Metalloproteinase Triple-helical Peptidase Activity and Collagen Specificity*

K. Brew, C. Overall, G. Fields, 2006, Journal of Biological Chemistry.

Calcium effects on calmodulin lysine reactivities.

D. Giedroc, K. Brew, D. Puett, 1987, Archives of biochemistry and biophysics.

Sequences of two highly divergent canine type c lysozymes: implications for the evolutionary origins of the lysozyme/alpha-lactalbumin superfamily.

K. Brew, J. Grobler, S. Pervaiz, 1994, Archives of biochemistry and biophysics.

Adipose pyruvate carboxylase: amino acid sequence and domain structure deduced from cDNA sequencing.

K. Brew, W. Xia, J. Zhang, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Tissue inhibitors of metalloproteinases: evolution, structure and function.

K. Brew, D. Dinakarpandian, H. Nagase, 2000, Biochimica et biophysica acta.

A New Role for TIMP-1 in Modulating Neurite Outgrowth and Morphology of Cortical Neurons

K. Brew, V. Dive, S. Rivera, 2009, PloS one.

Involvement of a region near valine-69 of tissue inhibitor of metalloproteinases (TIMP)-1 in the interaction with matrix metalloproteinase 3 (stromelysin 1).

K. Suzuki, K. Brew, H. Nagase, 1997, The Biochemical journal.

Thermodynamic Basis of Selectivity in the Interactions of Tissue Inhibitors of Metalloproteinases N-domains with Matrix Metalloproteinases-1, -3, and -14*

K. Brew, Ying Wu, Haiying Zou, 2016, The Journal of Biological Chemistry.

Proteins from the organic matrix of core-top and fossil planktonic foraminifera

K. Brew, L. Robbins, 1990 .

Comparison of the Amino Acid Sequence of Bovine α-Lactalbumin and Hens Egg White Lysozyme

Keith Brew, K. Brew, T. Vanaman, 1967 .

Amino acid sequence of a 32‐residue region around the thiol ester site in duck ovostatin

K. Brew, H. Nagase, 1987, FEBS letters.

Chemical and enzymatic synthesis of glycoconjugates 1. Enzymatic galactosylation of conduritol B

K. Brew, P. Wang, Libing Yu, 1995 .

The primary structure of human serum transferrin. The structures of seven cyanogen bromide fragments and the assembly of the complete structure.

K. Brew, R. MacGillivray, E. Méndez, 1983, The Journal of biological chemistry.

The role of alpha-lactalbumin and the A protein in lactose synthetase: a unique mechanism for the control of a biological reaction.

K. Brew, T. Vanaman, R. Hill, 1968, Proceedings of the National Academy of Sciences of the United States of America.

Glycosyltransferases in the Golgi membranes of onion stem.

K. Brew, J. Powell, 1974, The Biochemical journal.

Mutational analysis of the catalytic subunit of muscle protein phosphatase-1.

K. Brew, E. Y. Lee, Z. Zhang, 1996, Biochemistry.

Epitopes on the major capsid protein of simian virus 40.

K. Brew, L. Babe, W. Scott, 1989, The Journal of biological chemistry.

Crystal Structures of Apo- and Holo-bovine α-Lactalbumin at 2.2-Å Resolution Reveal an Effect of Calcium on Inter-lobe Interactions*

K. Brew, K. Acharya, E. Chrysina, 2000, The Journal of Biological Chemistry.

The complete amino acid sequence of bovine α-lactalbumin.

K. Brew, T. Vanaman, R. Hill, 1970 .

A comparison of the interactions of galactosyltransferase with a glycoprotein substrate (Ovalbumin) and with alpha-lactalbumin.

K. Brew, J. Powell, 1976, The Journal of biological chemistry.

Metal ion activation of galactosyltransferase.

K. Brew, J. Powell, 1976, The Journal of biological chemistry.

The amino-acid sequences of three cystine-free cyanogen-bromide fragments of human serum transferrin.

K. Brew, R. MacGillivray, M. R. Sutton, 1975, European Journal of Biochemistry.

4 – Comparison of the Structures of Alpha-Lactalbumin and Lysozyme*

K. Brew, R. Hill, H. Steinman, 1974 .

Proteolytic enzymes of the K-1 strain of Streptomyces griseus obtained from a commercial preparation (Pronase). Purification and characterization of the carboxypeptidase.

K. Brew, J. Powell, W. M. Awad, 1976, The Journal of biological chemistry.

The amino acid sequence of goat α-lactalbumin

K. Brew, R. MacGillivray, K. Barnes, 1979 .

Transferrin: internal homology in the amino acid sequence

K. Brew, R. MacGillivray, 1975, Science.

Purification and characterization of the seven cyanogen bromide fragments of human serum transferrin.

K. Brew, M. R. Sutton, 1974, The Biochemical journal.

The sequence of residues 1–26 of human serum transferrin

K. Brew, M. R. Sutton, 1974, FEBS letters.

The Complete Amino‐Acid Sequence of Human α‐Lactalbumin

K. Brew, J. Findlay, 1972 .

The complete amino-acid sequence of guinea-pig -lactalbumin.

K. Brew, 1972, European journal of biochemistry.

The preparation and characterization of two forms of bovine galactosyl transferase.

K. Brew, J. Powell, 1974, European journal of biochemistry.

Holoprotein formation of human chorionic gonadotropin: differential trace labeling with acetic anhydride.

K. Brew, D. Puett, S. Yadav, 1994, Molecular endocrinology.

Homology of beta-lactoglobulin, serum retinol-binding protein, and protein HC.

K. Brew, S. Pervaiz, 1985, Science.

Rapid collapse and slow structural reorganisation during the refolding of bovine alpha-lactalbumin.

C. Dobson, K. Brew, C. Robinson, 1999, Journal of molecular biology.

Primary structural requirements for the enzymatic formation of the N-glycosidic bond in glycoproteins. Studies with natural and synthetic peptides.

K. Brew, G. Hart, R. Bradshaw, 1979, The Journal of biological chemistry.

Some kinetic properties of human-milk galactosyl transferase.

D. G. Herries, K. Brew, B. Khatra, 1974, European journal of biochemistry.

Cloning and sequencing of cDNA of bovine N-acetylglucosamine (beta 1-4)galactosyltransferase.

K. Brew, H. Okayama, H. Narimatsu, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Homology and structure‐function correlations between α1 ‐acid glycoprotein and serum retinol‐binding protein and its relatives

K. Brew, S. Pervaiz, 1987, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

NMR structure of tissue inhibitor of metalloproteinases-1 implicates localized induced fit in recognition of matrix metalloproteinases.

K. Brew, V. Semenchenko, S. V. Van Doren, 2000, Journal of molecular biology.

Synthesis of 4-deoxy-D-xylo-hexose and 4-azido-4-deoxy-D-glucose and their effects on lactose synthase.

K. Brew, S. Sinha, 1980, Carbohydrate research.

Highly Efficient Chemoenzymatic Synthesis of α-Galactosyl Epitopes with a Recombinant α(1→3)-Galactosyltransferase

Peng George Wang, Keith Brew, Jianwen Fang, 1998 .

Isolation and characteristics of galactosyltransferase from Golgi membranes of lactating sheep mammary glands.

K. Brew, C. Smith, 1977, The Journal of biological chemistry.

Evolution of alpha-lactalbumins. The complete amino acid sequence of the alpha-lactalbumin from a marsupial (Macropus rufogriseus) and corrections to regions of sequence in bovine and goat alpha-lactalbumins.

K. Brew, J. Shewale, S. Sinha, 1984, The Journal of biological chemistry.

The structure, function, and evolution of alpha-lactalbumin.

K. Brew, T. Vanaman, R. Hill, 1968, Brookhaven symposia in biology.

Spectroscopic characterization by photodiode array detection of human urinary and amniotic protein HC subpopulations fractionated by anion-exchange and size-exclusion high-performance liquid chromatography.

K. Brew, J. Escribano, M. Calero, 1996, Journal of chromatography. A.

The complete amino acid sequence of human serum transferrin.

R T MacGillivray, K. Brew, R. MacGillivray, 1982, Proceedings of the National Academy of Sciences of the United States of America.

The tissue inhibitors of metalloproteinases (TIMPs): an ancient family with structural and functional diversity.

K. Brew, H. Nagase, 2010, Biochimica et biophysica acta.

Lactose synthetase: evolutionary origins, structure and control.

K. Brew, 1970, Essays in biochemistry.

The characterization of the whey proteins of guinea-pig milk. The isolation and properties of alpha-lactalbumin.

K. Brew, P. Campbell, 1967, The Biochemical journal.

Macromolecules from Living and Fossil Biominerals

K. Brew, G. Muyzer, L. Robbins, 1993 .

Macromolecules from Living and Fossil Biominerals Implications for the Establishment of Molecular Phylogenies

K. Brew, G. Muyzer, L. Robbins, 1993 .

Differential trace labeling of calmodulin: investigation of binding sites and conformational states by individual lysine reactivities. Effects of beta-endorphin, trifluoperazine, and ethylene glycol bis(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid.

D. Giedroc, K. Brew, D. Puett, 1985, The Journal of biological chemistry.

Lactose synthetase.

K. Brew, R. Hill, 1975, Advances in enzymology and related areas of molecular biology.

Selective Modulation of Matrix Metalloproteinase 9 (MMP-9) Functions via Exosite Inhibition*

Robert P. Hammer, Keith Brew, Gregg B. Fields, 2008, Journal of Biological Chemistry.

Naturally-Occurring Polypeptide Inhibitors: Cystatins/Stefins, Inhibitors of Apoptosis (IAPs), Serpins, and Tissue Inhibitors of Metalloproteinases (TIMPs)

K. Brew, M. Lizotte-Waniewski, 2016 .

Role of conserved residues in structure and stability: Tryptophans of human serum retinol‐binding protein, a model for the lipocalin superfamily

K. Brew, L. Greene, K. Acharya, 2001, Protein Science.

Characteristics of the binding of Ca2+ and other divalent metal ions to bovine alpha-lactalbumin.

K. Brew, M. Kronman, S. Sinha, 1981, The Journal of biological chemistry.

Enzymic characteristics of fat globule membranes from bovine colostrum and bovine milk

K. Brew, J. Powell, U. Järlfors, 1977, The Journal of cell biology.

Phage Display of Tissue Inhibitor of Metalloproteinases-2 (TIMP-2)

K. Brew, S. Sidhu, Yingnan Zhang, 2011, The Journal of Biological Chemistry.

Family 6 Glycosyltransferases in Vertebrates and Bacteria: Inactivation and Horizontal Gene Transfer May Enhance Mutualism between Vertebrates and Bacteria*

K. Brew, K. Acharya, P. Tumbale, 2010, The Journal of Biological Chemistry.

Reflections on the evolution of the vertebrate tissue inhibitors of metalloproteinases

K. Brew, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Thermodynamic and mechanistic insights into coupled binding and unwinding of collagen by matrix metalloproteinase 1.

K. Brew, S. W. Manka, 2020, Journal of molecular biology.

Thermodynamic and mechanistic insights into coupled binding and unwinding of collagen by matrix metalloproteinase 1

K. Brew, S. W. Manka, 2020, bioRxiv.

Purification and characterization of the major whey proteins from the milks of the bottlenose dolphin (Tursiops truncatus), the Florida manatee (Trichechus manatus latirostris), and the beagle (Canis familiaris).

K. Brew, S. Pervaiz, 1986, Archives of biochemistry and biophysics.

Protein Engineering of the Tissue Inhibitor of Metalloproteinase 1 (TIMP-1) Inhibitory Domain

K. Brew, H. Nagase, Ying Chen, 2003, The Journal of Biological Chemistry.

Crystal structures of guinea-pig, goat and bovine alpha-lactalbumin highlight the enhanced conformational flexibility of regions that are significant for its action in lactose synthase.

K. Brew, A. Pike, K. Acharya, 1996, Structure.

Stability, activity and flexibility in α-lactalbumin

K. Brew, L. Greene, K. Acharya, 1999 .

Structural evidence for the presence of a secondary calcium binding site in human alpha-lactalbumin.

K. Brew, K. Acharya, N. Chandra, 1998, Biochemistry.

Ovostatin: a novel proteinase inhibitor from chicken egg white. I. Purification, physicochemical properties, and tissue distribution of ovostatin.

K. Brew, J. Woessner, E. D. Harris, 1983, The Journal of biological chemistry.

The Primary Structure of Human Serum Transferrin

Sudhir, K. Brew, E. Méndez, 2001 .

Sequence of a full-length cDNA for rat lung beta-galactoside-binding protein: primary and secondary structure of the lectin.

K. Brew, T. Miller, D. Massaro, 1988, Biochemistry.

Cloning and mapping of a testis-specific gene with sequence similarity to a sperm-coating glycoprotein gene.

P. Goodfellow, K. Brew, M. Kasahara, 1989, Genomics.

On the interaction of alpha-lactalbumin and galactosyltransferase during lactose synthesis.

K. Brew, J. Powell, 1975, The Journal of biological chemistry.

Increased backbone mobility in beta-barrel enhances entropy gain driving binding of N-TIMP-1 to MMP-3.

Keith Brew, K. Brew, V. Semenchenko, 2003, Journal of molecular biology.

Tissue inhibitor of metalloproteinases-1 promotes liver metastasis by induction of hepatocyte growth factor signaling.

A. Krüger, K. Brew, L. Coussens, 2007, Cancer research.

TIMP-3 Binds to Sulfated Glycosaminoglycans of the Extracellular Matrix*

K. Brew, J. Woessner, Wei-hsuan Yu, 2000, The Journal of Biological Chemistry.

Peptide maps at picomolar levels obtained by reversed-phase high-performance liquid chromatography and pre-column derivatization with phenyl isothiocyanate. Microsequencing of Phenylthiocarbamyl Peptides.

K. Brew, E. Méndez, S. Yadav, 1991, Journal of Chromatography A.

The whey proteins of pig's milk. Isolation and characterization of a beta-lactoglobulin.

K. Brew, E. Kessler, Keith Brew, 1970, Biochimica et biophysica acta.

Crystal Structure of the Catalytic Domain of Matrix Metalloproteinase-1 in Complex with the Inhibitory Domain of Tissue Inhibitor of Metalloproteinase-1*

Keith Brew, K Ravi Acharya, K. Brew, 2006, Journal of Biological Chemistry.

An analysis of the circular dichroism of the lysozyme- -lactalbumin group of proteins.

K. Brew, D. Cowburn, W. Gratzer, 1972, Biochemistry.

Studies on the biosynthesis of protein by lactating guinea-pig mammary gland. Characteristics of the synthesis of alpha-lactalbumin and total protein by slices and cell-free systems.

K. Brew, P. Campbell, 1967, The Biochemical journal.

The disulfide bonds of bovine alpha-lactalbumin.

K. Brew, T. Vanaman, R. Hill, 1970, The Journal of biological chemistry.

Nitration of tyrosyl residues in human alpha-lactalbumin. Effect on lactose synthase specifier activity.

K. Brew, J. Prieels, M. Dolmans, 1975, European journal of biochemistry.

Conformational changes induced by binding UDP-2F-galactose to alpha-1,3 galactosyltransferase- implications for catalysis.

S. Withers, K. Brew, K. Acharya, 2007, Journal of molecular biology.

Application of topologically constrained mini-proteins as ligands, substrates, and inhibitors.

K. Brew, G. Fields, Janelle L. Lauer-Fields, 2007, Methods in molecular biology.

Study by mutagenesis of the roles of two aromatic clusters of alpha-lactalbumin in aspects of its action in the lactose synthase system.

J A Grobler, K. Brew, A. Pike, 1994, The Journal of biological chemistry.

Structural Basis of Ordered Binding of Donor and Acceptor Substrates to the Retaining Glycosyltransferase, α-1,3-Galactosyltransferase*

G. J. Swaminathan, K. Brew, E. Boix, 2002, The Journal of Biological Chemistry.

Signaling Metastasis by Induction of Hepatocyte Growth Factor Tissue Inhibitor of Metalloproteinases-1 Promotes Liver

A. Krüger, K. Brew, L. Coussens, 2007 .

TIMP-3 Is a Potent Inhibitor of Aggrecanase 1 (ADAM-TS4) and Aggrecanase 2 (ADAM-TS5)*

M Kashiwagi, K. Brew, M. Kashiwagi, 2001, The Journal of Biological Chemistry.

The structure and regulation of the lactose synthetase system.

K. Brew, J. Findlay, B. Khatra, 1972, The Biochemical journal.

Engineering of tissue inhibitor of metalloproteinases mutants as potential therapeutics

K. Brew, H. Nagase, 2002, Arthritis research.

Letter to the Editor: 1H, 13C and 15N resonance assignments and secondary structure of the N-terminal domain of human tissue inhibitor of metalloproteinases-1

K. Brew, S. V. Van Doren, W. Huang, 1999, Journal of biomolecular NMR.

Engineering of Selective TIMPs

K. Brew, W. Bode, K. Maskos, 1999, Annals of the New York Academy of Sciences.

Residue 2 of TIMP-1 Is a Major Determinant of Affinity and Specificity for Matrix Metalloproteinases but Effects of Substitutions Do Not Correlate with Those of the Corresponding P1′ Residue of Substrate*

K. Brew, Yajing Hu, W. Bode, 1999, The Journal of Biological Chemistry.

Structure of UDP Complex of UDP-galactose:β-Galactoside-α-1,3-galactosyltransferase at 1.53-Å Resolution Reveals a Conformational Change in the Catalytically Important C Terminus*

G. J. Swaminathan, K. Brew, R. Natesh, 2001, The Journal of Biological Chemistry.

Mapping of the calpain proteolysis products of the junctional foot protein of the skeletal muscle triad junction

K. Brew, A. Caswell, R. Mellgren, 1992, The Journal of Membrane Biology.

STRUCTURAL BASIS OF THE REGULATION OF GALACTOSYLTRANSFERASE

K. Brew, R. Richardson, S. Sinha, 1979 .

Puromycin does not inactivate the galactrosyltransferase of Golgi membranes.

K. Brew, C. Smith, J. Powell, 1975, Biochemical and biophysical research communications.

Roles of active site tryptophans in substrate binding and catalysis by alpha-1,3 galactosyltransferase.

K. Brew, R. Natesh, K. Acharya, 2004, Glycobiology.

THE PROTEOLYTIC ENZYMES OF THE K-1 STRAIN OF STREPTOMYCES GRISEUS OBTAINED FROM A COMMERCIAL PREPARATION (PRONASE). XI. EVOLUTIONARY IMPLICATIONS

K. Brew, J. Powell, W. M. Awad, 1976 .

Constraining specificity in the N‐domain of tissue inhibitor of metalloproteinases‐1; gelatinase‐selective inhibitors

K. Brew, K. Acharya, H. Bahudhanapati, 2007, Protein science : a publication of the Protein Society.

Engineered Sarafotoxins as Tissue Inhibitor of Metalloproteinases-like Matrix Metalloproteinase Inhibitors*

K. Brew, G. Fields, M. Cudic, 2007, Journal of Biological Chemistry.

The complete amino acid sequence of a bacteriochlorophyll a-protein from Prosthecochloris aestuarii.

K. Brew, R. Fenna, S. T. Daurat-Larroque, 1986, The Journal of biological chemistry.

Evidence for a thiol ester in duck ovostatin (ovomacroglobulin).

K. Brew, E. D. Harris, H. Nagase, 1986, Journal of Biological Chemistry.

Triple-helical transition state analogues: a new class of selective matrix metalloproteinase inhibitors.

K. Brew, G. Fields, Shunzi Li, 2007, Journal of the American Chemical Society.

Crystal structure of alpha-1,3-galactosyltransferase (alpha3GT) in a complex with p-nitrophenyl-beta-galactoside (pNPbetaGal).

K. Brew, K. Acharya, H. Jamaluddin, 2009, Biochemical and biophysical research communications.

Characterization of a Metal-independent CAZy Family 6 Glycosyltransferase from Bacteroides ovatus*

K. Brew, P. Tumbale, 2009, The Journal of Biological Chemistry.

Structural basis of UDP-galactose binding by alpha-1,3-galactosyltransferase (alpha3GT): role of negative charge on aspartic acid 316 in structure and activity.

K. Brew, K. Acharya, H. Jamaluddin, 2008, Biochemistry.

Specificity and Mechanism of Metal Ion Activation in UDP-galactose:β-Galactoside-α-1,3-galactosyltransferase*

K. Brew, P. Wang, Yingnan Zhang, 2001, The Journal of Biological Chemistry.

Protein Folding Monitored at Individual Residues During a Two-Dimensional NMR Experiment

C M Dobson, C. Dobson, K. Brew, 1996, Science.

Comparison of the amino acid sequence of bovine alpha-lactalbumin and hens egg white lysozyme.

K. Brew, T. Vanaman, R. Hill, 1967, The Journal of biological chemistry.

Molecular conformation and fluorescence properties of lactalbumin from four animal species.

K. Brew, M. Kronman, P. B. Sommers, 1973, Biochemical and biophysical research communications.

Preparation and characterization of an NH2-terminal fragment of human serum transferrin containing a single iron-binding site.

K. Brew, J. Lineback-Zins, 1980, The Journal of biological chemistry.

Structure of human ACE gives new insights into inhibitor binding and design.

K. Brew, 2003, Trends in pharmacological sciences.

Recombinant bovine alpha-lactalbumin obtained by limited proteolysis of a fusion protein expressed at high levels in Escherichia coli.

K. Brew, G. Conner, W. Scott, 1989, The Journal of biological chemistry.

Calcium regulates folding and disulfide-bond formation in α-lactalbumin

K. Brew, K. Rao, 1989 .

Reactive-site mutants of N-TIMP-3 that selectively inhibit ADAMTS-4 and ADAMTS-5: biological and structural implications

J. Enghild, K. Brew, M. Kashiwagi, 2010, The Biochemical journal.

STUDIES OF THE MOLECULAR LOCALIZATION OF PROTEIN-PROTEIN INTERACTION SITES IN THE LACTOSE SYNTHASE SYSTEM1

K. Brew, S. Sinha, 1982 .

CRYSTAL STRUCTURE OF APO-BOVINE ALPHA-LACTALBUMIN

K. Brew, K. Acharya, E. Chrysina, 2000 .

Effects of interaction with calcineurin on the reactivities of calmodulin lysines.

K. Brew, Q. Wei, K. Carraway, 1988, The Journal of biological chemistry.

Hypothesis: Metalloproteinase Inhibitors Decrease Risks of Cardiovascular Disease.

K. Brew, M. Lizotte-Waniewski, C. Hennekens, 2016, Journal of Cardiovascular Pharmacology and Therapeutics.

Primary structure of the major isomorph of the crustacean hyperglycemic hormone (CHH-I) from the sinus gland of the Mexican crayfish Procambarus bouvieri (Ortmann): Interspecies comparison

K. Brew, J. Shabanowitz, D. Hunt, 1993, Peptides.

Catalytic properties of ADAM12 and its domain deletion mutants.

J. Enghild, K. Brew, H. P. Sørensen, 2008, Biochemistry.

Association of calmodulin and smooth muscle myosin light chain kinase: Application of a lable selection technique with trace acetylated calmodulin

K. Brew, A. Means, K. Carraway, 1987, Proteins.

Roles of individual enzyme-substrate interactions by alpha-1,3-galactosyltransferase in catalysis and specificity.

Keith Brew, Zhihong Xie, K Ravi Acharya, 2003, Biochemistry.

Entropy Increases from Different Sources Support the High-affinity Binding of the N-terminal Inhibitory Domains of Tissue Inhibitors of Metalloproteinases to the Catalytic Domains of Matrix Metalloproteinases-1 and -3*

K. Brew, Ying Wu, S. V. Van Doren, 2011, The Journal of Biological Chemistry.

Milk Proteins | α-Lactalbumin

K. Brew, 2011 .

Drosophila TIMP is a potent inhibitor of MMPs and TACE: similarities in structure and function to TIMP-3.

K. Brew, Zhihong Xie, Elena Filenova, 2003, Biochemistry.

Crystal structure of alpha-1,3-galactosyltransferase (alpha3GT) in a complex with p-nitrophenyl-beta-galactoside (pNPbetaGal).

K. Brew, H. Jamaluddin, N. Thiyagarajan, 2009, Biochemical and biophysical research communications.

Effect of alloxan-diabetes on the glucose-ATP phosphotransferase activity of adipose tissue.

K. Brew, P. Mclean, J. Brown, 1966, Biochemical and biophysical research communications.