J. G. Patton

发表

Mutation of PTB binding sites causes misregulation of alternative 3' splice site selection in vivo.

I. Pérez, C. H. Lin, J. G. McAfee, 1997, RNA.

Biogenesis, delivery, and function of extracellular RNA

Michael T. McManus, Alissa M. Weaver, J. G. Patton, 2015, Journal of extracellular vesicles.

Alternative splicing in the control of gene expression.

J. G. Patton, C. W. Smith, B. Nadal-Ginard, 1989, Annual review of genetics.

Transcriptome-wide analysis of small RNA expression in early zebrafish development.

J. G. Patton, A. Rokas, L. Salichos, 2012, RNA.

Multiplex Conditional Mutagenesis Using Transgenic Expression of Cas9 and sgRNAs

Linlin Yin, J. G. Patton, S. Burgess, 2015, Genetics.

Genomic organization of microRNAs

J. G. Patton, Abigail F. Olena, 2009, Journal of cellular physiology.

Go with the Flow: Fluid Roles for miRNAs in Vertebrate Osmoregulation

J. G. Patton, A. Flynt, 2015 .

Zebrafish miR-214 modulates Hedgehog signaling to specify muscle cell fate

J. G. Patton, A. Flynt, Nan Li, 2007, Nature Genetics.

Identification of a Paralog-Specific Notch1 Intracellular Domain Degron.

J. G. Patton, Ethan Lee, A. Salic, 2016, Cell reports.

Splicing fidelity, enhancers, and disease.

J. G. Patton, N. Shariat, A. S. Solis, 2008, Frontiers in bioscience : a journal and virtual library.

The Splicing Factor PSF is Part of a Large Complex That Assembles in the Absence of pre-mRNA and Contains All 5 snRNPs

Andrew J Link, J. G. Patton, A. Link, 2006, RNA biology.

Genome-wide microRNA screening in Nile tilapia reveals pervasive isomiRs’ transcription, sex-biased arm switching and increasing complexity of expression throughout development

J. G. Patton, M. Acencio, N. Lemke, 2018, Scientific Reports.

Reassessment of Exosome Composition

Dylan T Burnette, L. Rome, J. G. Patton, 2019, Cell.

Neurotransmitter-Regulated Regeneration in the Zebrafish Retina

J. G. Patton, Dominic Didiano, Mahesh B. Rao, 2017, Stem cell reports.

Initiation of Retina Regeneration By a Conserved Mechanism of Adult Neurogenesis

J. G. Patton, Dominic Didiano, Mahesh B. Rao, 2016, bioRxiv.

A new double-stranded RNA-binding protein that interacts with PKR.

J. G. Patton, C. Coolidge, 2000, Nucleic acids research.

alpha-tropomyosin exon 2 Enhancer elements activate the weak 3' splice site of

J. G. Patton, B. Dye, Chorng-Horng Lin, 1998 .

U1 precursors: variant 3' flanking sequences are transcribed in human cells

J. G. Patton, E. Wieben, 1987, The Journal of cell biology.

Cloning and character!zation of PSF, a novel pre-mRNA sphcing factor

J. G. Patton, B. Nadal-Ginard, J. Galcerán, 2007 .

A molecular basis for variation in clinical severity of isolated growth hormone deficiency type II.

J. G. Patton, J. Cogan, J. Phillips, 2009, The Journal of clinical endocrinology and metabolism.

miR-8 microRNAs regulate the response to osmotic stress in zebrafish embryos

J. G. Patton, A. Flynt, Nan Li, 2009, The Journal of cell biology.

Dynamic sorting of nuclear components into distinct nucleolar caps during transcriptional inhibition.

J. G. Patton, X. Darzacq, B. Dye, 2005, Molecular biology of the cell.

Alternative Pre‐mRNA Splicing: Prevalence, Mechanisms, and Disease

J. G. Patton, Christopher W. J. Smith, 2002 .

Direct evidence that polypyrimidine tract binding protein (PTB) is essential for internal initiation of translation of encephalomyocarditis virus RNA.

J. G. Patton, R. Jackson, A. Kaminski, 1995, RNA.

Quantitative Proteomic Analysis of Small and Large Extracellular Vesicles (EVs) Reveals Enrichment of Adhesion Proteins in Small EVs.

Alissa M. Weaver, J. G. Patton, J. Franklin, 2019, Journal of proteome research.

miRNA Biogenesis and Function

J. G. Patton, Abigail F. Olena, 2014 .

RNA Interference and microRNAs in Zebra Fish

J. G. Patton, A. Flynt, Elizabeth J. Thatcher, 2009 .

A switch in the development: microRNA arm usage screening in zebrafish suggests an important role of arm switching events in ontogenesis

J. G. Patton, L. Bovolenta, D. Pinhal, 2021 .

RNAi-Mediated Gene silencing in Zebrafish Triggered by Convergent Transcription

J. G. Patton, Chunyao Wei, Omozusi E. Andrews, 2014, Scientific Reports.

Small RNAs have a big impact on regeneration

J. G. Patton, Elizabeth J. Thatcher, 2010, RNA biology.

Regulation of zebrafish fin regeneration by microRNAs

J. G. Patton, Elizabeth J. Thatcher, K. Anderson, 2008, Proceedings of the National Academy of Sciences.

siRNA therapeutics: big potential from small RNAs

J. G. Patton, A. Flynt, J G Patton, 2005, Gene Therapy.

Genome-wide microRNA screening in Nile tilapia reveals pervasive isomiRs’ transcription, sex-biased arm switching and increasing complexity of expression throughout development

J. G. Patton, M. Acencio, N. Lemke, 2018, Scientific Reports.

Dynamic miRNA expression patterns during retinal regeneration in zebrafish: Reduced dicer or miRNA expression suppresses proliferation of Müller Glia‐derived neuronal progenitor cells

J. G. Patton, D. Hyde, T. Bailey, 2014, Developmental dynamics : an official publication of the American Association of Anatomists.

Dispatched Homolog 2 is targeted by miR-214 through a combination of three weak microRNA recognition sites

J. G. Patton, A. Flynt, Nan Li, 2008, Nucleic acids research.

Genomic Organization of Zebrafish microRNAs

Ima Paydar, J. G. Patton, Elizabeth J. Thatcher, 2008, BMC Genomics.

Reassessment of Exosome Composition

Dylan T Burnette, L. Rome, J. G. Patton, 2019, Cell.

Alternative splicing is an efficient mechanism for the generation of protein diversity: contractile protein genes as a model system.

J. G. Patton, C. W. Smith, B. Nadal-Ginard, 1991, Advances in enzyme regulation.

A comparative analysis of heart microRNAs in vertebrates brings novel insights into the evolution of genetic regulatory networks

J. G. Patton, N. Lemke, L. Bovolenta, 2021, BMC genomics.

KRAS-MEK Signaling Controls Ago2 Sorting into Exosomes

Alissa M. Weaver, J. G. Patton, R. Coffey, 2016, Cell reports.

Blocking Zebrafish MicroRNAs with Morpholinos.

J. G. Patton, A. Flynt, Mahesh B Rao, 2017, Methods in molecular biology.

Regulation of endoderm formation and left-right asymmetry by miR-92 during early zebrafish development

J. G. Patton, Nan Li, Chunyao Wei, 2011, Development.

Interaction of lncRNA MIR100HG with hnRNPA2B1 facilitates m6A-dependent stabilization of TCF7L2 mRNA and colorectal cancer progression

T. Yeatman, J. G. Patton, R. Coffey, 2022, Molecular cancer.

miRNAs and Müller Glia Reprogramming During Retina Regeneration

J. G. Patton, Claire Ferguson, Matthew R. Kent, 2021, Frontiers in Cell and Developmental Biology.

miR-27 regulates chondrogenesis by suppressing focal adhesion kinase during pharyngeal arch development

J. G. Patton, Chunyao Wei, N. Kara, 2017, Developmental biology.

KRAS-dependent sorting of miRNA to exosomes

Alissa M. Weaver, J. G. Patton, S. Levy, 2015, eLife.

An RNA recognition motif (RRM) is required for the localization of PTB-associated splicing factor (PSF) to subnuclear speckles.

J. G. Patton, B. Dye, 2001, Experimental cell research.

Enhancer elements activate the weak 3' splice site of alpha-tropomyosin exon 2.

C. H. Lin, J. G. Patton, B. Dye, 1998, RNA.

Functional crosstalk between exon enhancers, polypyrimidine tracts and branchpoint sequences

J. G. Patton, M. Buvoli, S. Mayer, 1997, The EMBO journal.

miR-153 Regulates SNAP-25, Synaptic Transmission, and Neuronal Development

J. G. Patton, K. Broadie, Chunyao Wei, 2013, PloS one.

Cloning and characterization of PSF, a novel pre-mRNA splicing factor.

J. G. Patton, P. Tempst, J. Galceran, 1993, Genes & development.

Biogenesis of RNA-containing extracellular vesicles at endoplasmic reticulum membrane contact sites

Alissa M. Weaver, J. G. Patton, J. Ping, 2020, bioRxiv.

Activation of α-Tropomyosin Exon 2 Is Regulated by the SR Protein 9G8 and Heterogeneous Nuclear Ribonucleoproteins H and F

J. G. Patton, J. Crawford, 2006, Molecular and Cellular Biology.

The Extracellular RNA Communication Consortium: Establishing Foundational Knowledge and Technologies for Extracellular RNA Research

Nikita A. Sakhanenko, Michael T. McManus, Andrew R. Jackson, 2019, Cell.

Characterization and molecular cloning of polypyrimidine tract-binding protein: a component of a complex necessary for pre-mRNA splicing.

J. G. Patton, P. Tempst, B. Nadal-Ginard, 1991, Genes & development.

Functional analysis of the polypyrimidine tract in pre-mRNA splicing.

J. G. Patton, C J Coolidge, R J Seely, 1997, Nucleic acids research.

Cloning and domain structure of the mammalian splicing factor U2AF

Michael R. Green, J. G. Patton, P. Zamore, 1992, Nature.

The miR-216a-Dot1l Regulatory Axis Is Necessary and Sufficient for Müller Glia Reprogramming during Retina Regeneration

J. G. Patton, N. Kara, Dominic Didiano, 2019, Cell reports.

Growth Hormone Deficiency and Splicing Fidelity

J. G. Patton, J. Phillips, A. S. Solis, 2008, Journal of Biological Chemistry.

Scanning from an independently specified branch point defines the 3′ splice site of mammalian introns

J. G. Patton, Christopher W. J. Smith, B. Nadal-Ginard, 1989, Nature.

MicroRNAs in Cancer Progression

J. G. Patton, Omozusi E. Andrews, 2014 .

GH1 splicing is regulated by multiple enhancers whose mutation produces a dominant-negative GH isoform that can be degraded by allele-specific small interfering RNA (siRNA).

J. G. Patton, J. Phillips, A. Flynt, 2004, Endocrinology.

Nuclear relocalization of the pre-mRNA splicing factor PSF during apoptosis involves hyperphosphorylation, masking of antigenic epitopes, and changes in protein interactions.

J Vandekerckhove, J. G. Patton, B. Dye, 2001, Molecular biology of the cell.

VAP-A and its binding partner CERT drive biogenesis of RNA-containing extracellular vesicles at ER membrane contact sites.

Bryan A. Millis, Alissa M. Weaver, J. G. Patton, 2022, Developmental cell.

Rab13 regulates sEV secretion in mutant KRAS colorectal cancer cells

J. G. Patton, R. Coffey, J. Franklin, 2020, Scientific Reports.

Induction of a proliferative response in the zebrafish retina by injection of extracellular vesicles.

J. G. Patton, Qi Liu, E. Levine, 2020, Experimental eye research.

MiRNA expression analysis during normal zebrafish development and following inhibition of the Hedgehog and Notch signaling pathways

J. G. Patton, A. Flynt, Nan Li, 2007, Developmental dynamics : an official publication of the American Association of Anatomists.

miR-216a regulates snx5, a novel notch signaling pathway component, during zebrafish retinal development.

J. G. Patton, Shu-Yu Wu, Abigail F. Olena, 2015, Developmental biology.

PSF and p54nrb bind a conserved stem in U5 snRNA.

I. Pérez, J. G. Patton, B. Dye, 2002, RNA.

Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes

Alissa M. Weaver, J. G. Patton, S. Levy, 2016, Scientific Reports.

lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/β-catenin signaling

T. Yeatman, J. G. Patton, R. Coffey, 2017, Nature Medicine.

Regulation of Alternative Splicing by SRrp86 and Its Interacting Proteins

J. G. Patton, A. Link, Jun Li, 2003, Molecular and Cellular Biology.

Regulation of alternative splicing by SRrp86 through coactivation and repression of specific SR proteins.

J. G. Patton, D. Barnard, Jun Li, 2002, RNA.

Identiﬁcation and Characterization of a Novel Serine-Arginine-Rich Splicing Regulatory Protein

J. G. Patton, D. Barnard, 2022 .

Alpha-tropomyosin mutually exclusive exon selection: competition between branchpoint/polypyrimidine tracts determines default exon choice.

J. G. Patton, C. W. Smith, B. Nadal-Ginard, 1991, Genes & development.

A novel set of spliceosome‐associated proteins and the essential splicing factor PSF bind stably to pre‐mRNA prior to catalytic step II of the splicing reaction.

J. G. Patton, R. Reed, O. Gozani, 1994, The EMBO journal.

The role of miR-124a in early development of the Xenopus eye

J. G. Patton, Jane Y. Wu, A. Flynt, 2009, Mechanisms of Development.

A Unique Glutamic Acid-Lysine (EK) Domain Acts as a Splicing Inhibitor*

J. G. Patton, D. Barnard, Jun Li, 2002, The Journal of Biological Chemistry.

Diverse Long RNAs Are Differentially Sorted into Extracellular Vesicles Secreted by Colorectal Cancer Cells.

Alissa M. Weaver, J. G. Patton, S. Levy, 2018, Cell reports.

Multiple RRMs contribute to RNA binding specificity and affinity for polypyrimidine tract binding protein.

I. Pérez, J. G. McAfee, J. G. Patton, 1997, Biochemistry.

Regulation of alternative 3' splice site selection by constitutive splicing factors.

C. H. Lin, J. G. Patton, 1995, RNA.

Identification of pre-mRNA Splicing Factors and Analysis of RNA—Protein Interaction

J. G. McAfee, J. G. Patton, B. Dye, 1997 .

Interaction of protein phosphatase type 1 with a splicing factor

J. G. Patton, D. Hartshorne, K. Hirano, 1996, FEBS letters.

The involvement of a spliceosome component in internal initiation of human rhinovirus RNA translation.

J. G. Patton, R. Jackson, A. Borman, 1993, The Journal of general virology.

Identification of PSF, the polypyrimidine tract‐binding protein–associated splicing factor, as a developmentally regulated neuronal protein

G. Moonen, J. G. Patton, B. Malgrange, 1999, Journal of neuroscience research.

Disruption of exon definition produces a dominant-negative growth hormone isoform that causes somatotroph death and IGHD II

J. G. Patton, I. Robinson, J. Phillips, 2003, Human Genetics.

Inhibition of GABAA-ρ receptors induces retina regeneration in zebrafish

J. G. Patton, Matthew R. Kent, Nergis Kara, 2020, Neural regeneration research.

Developmental regulation of Wnt signaling by Nagk and the UDP-GlcNAc salvage pathway

J. G. Patton, Ethan Lee, D. Robbins, 2019, Mechanisms of Development.

Damage-induced senescent immune cells regulate regeneration of the zebrafish retina

J. G. Patton, Kyle T Vallone, Gregory Konar, 2023, bioRxiv.

Depletion of METTL3 alters cellular and extracellular levels of miRNAs containing m6A consensus sequences

Alissa M. Weaver, J. G. Patton, R. Coffey, 2021, Heliyon.

Rescue of pituitary function in a mouse model of isolated growth hormone deficiency type II by RNA interference.

J. G. Patton, I. Robinson, J. Phillips, 2008, Endocrinology.

miR-203 regulates progenitor cell proliferation during adult zebrafish retina regeneration.

J. G. Patton, D. Hyde, Kamya Rajaram, 2014, Developmental biology.

Strain-specific suppression of microRNA-320 by carcinogenic Helicobacter pylori promotes expression of the antiapoptotic protein Mcl-1.

J. G. Patton, J. Noto, R. Peek, 2013, American journal of physiology. Gastrointestinal and liver physiology.

Argonautes in extracellular vesicles: artifact or selected cargo?

Alissa M. Weaver, J. G. Patton, 2019, Cancer research.

Systematic Assessment of Small RNA Profiling in Human Extracellular Vesicles

Alissa M. Weaver, J. G. Patton, T. Dawson, 2023, Cancers.

A transcription factor network controls cell migration and fate decisions in the developing zebrafish pineal complex

J. G. Patton, J. Gamse, Sataree Khuansuwan, 2016, Development.

Analysis of SRrp86-regulated alternative splicing

J. G. Patton, A. S. Solis, Amanda S. Solis, 2010, RNA biology.

Author response: KRAS-dependent sorting of miRNA to exosomes

Alissa M. Weaver, J. G. Patton, S. Levy, 2015 .

Crosstalk between planar cell polarity signaling and miR-8 control of NHERF1-mediated actin reorganization

J. G. Patton, A. Flynt, 2010, Cell cycle.

Technical brief: Constant intense light exposure to lesion and initiate regeneration in normally pigmented zebrafish

J. G. Patton, Kamya Rajaram, E. Summerbell, 2014, Molecular vision.

The Extracellular RNA Communication Consortium: Establishing Foundational Knowledge and Technologies for Extracellular RNA Research

Nikita A. Sakhanenko, Michael T. McManus, Andrew R. Jackson, 2019, Cell.