P. Grabowski

发表

A neuron-specific splicing switch mediated by an array of pre-mRNA repressor sites: evidence of a regulatory role for the polypyrimidine tract binding protein and a brain-specific PTB counterpart.

M. Ashiya, P. Grabowski, 1997, RNA.

Function of quaking in myelination: Regulation of alternative splicing

P. Grabowski, Jiang I. Wu, R. B. Reed, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Self-splicing RNA: Autoexcision and autocyclization of the ribosomal RNA intervening sequence of tetrahymena

T. Cech, P. Grabowski, A. Zaug, 1982, Cell.

In vitro splicing of the ribosomal RNA precursor of tetrahymena: Involvement of a guanosine nucleotide in the excision of the intervening sequence

T. Cech, P. Grabowski, A. Zaug, 1981, Cell.

Alternative splicing takes shape during neuronal development.

P. Grabowski, 2011, Current opinion in genetics & development.

Alternative RNA splicing in the nervous system

D. Black, P. Grabowski, 2001, Progress in Neurobiology.

Splicing Error in E1α Pyruvate Dehydrogenase mRNA Caused by Novel Intronic Mutation Responsible for Lactic Acidosis and Mental Retardation*

M. Abitbol, P. Grabowski, G. Touati, 2003, The Journal of Biological Chemistry.

Alternative pre-mRNA splicing and neuronal function.

D L Black, D. Black, P. Grabowski, 2003, Progress in molecular and subcellular biology.

Combinatorial splicing of exon pairs by two-site binding of U1 small nuclear ribonucleoprotein particle

P. Grabowski, F. Nasim, H. Kuo, 1991, Molecular and Cellular Biology.

Control of alternative splicing by the differential binding of U1 small nuclear ribonucleoprotein particle.

P. Grabowski, F. Nasim, P J Grabowski, 1991, Science.

The intervening sequence of the ribosomal RNA precursor is converted to a circular RNA in isolated nuclei of tetrahymena

T. Cech, P. Grabowski, A. Zaug, 1981, Cell.

Exon Silencing by UAGG Motifs in Response to Neuronal Excitation

Ping An, P. Grabowski, P. An, 2007, PLoS biology.

Cofactor requirements of splicing of purified messenger RNA precursors

P. Sharp, P. Grabowski, R. Padgett, 1984, Nature.

Alternative Splicing of a Novel Inducible Exon Diversifies the CASK Guanylate Kinase Domain

Gene W. Yeo, P. Grabowski, P. An, 2012, Journal of nucleic acids.

Splicing of messenger RNA precursors.

P. Sharp, P. Grabowski, R. Padgett, 1987, Annual review of biochemistry.

A Sequential splicing mechanism promotes selection of an optimal exon by repositioning a downstream 5' splice site in preprotachykinin pre-mRNA.

P. Grabowski, P. Spears, F. Nasim, 1990, Genes & development.

Lariat RNA's as intermediates and products in the splicing of messenger RNA precursors.

P. Sharp, P. Grabowski, R. Padgett, 1984, Science.

Meayamycin inhibits pre–messenger RNA splicing and exhibits picomolar activity against multidrug-resistant cells

M. Moore, P. Grabowski, B. Day, 2009, Molecular Cancer Therapeutics.

Splicing-active nuclear extracts from rat brain.

P. Grabowski, 2005, Methods.

U1 snRNP targets an essential splicing factor, U2AF65, to the 3' splice site by a network of interactions spanning the exon.

P. Grabowski, B. Hoffman, B E Hoffman, 1992, Genes & development.

Heterogeneous nuclear ribonucleoproteins: role in RNA splicing.

G. Dreyfuss, P. Grabowski, P. Sharp, 1986, Science.

Isolation and analysis of splicing complexes.

P. Grabowski, 1990, Methods in enzymology.

Affinity chromatography of splicing complexes: U2, U5, and U4 + U6 small nuclear ribonucleoprotein particles in the spliceosome.

P. Sharp, P. Grabowski, 1986, Science.

Splicing messenger RNA precursors: branch sites and lariat RNAs

P. Sharp, P. Grabowski, R. Padgett, 1985 .

Messenger RNA splicing in vitro: An excised intervening sequence and a potential intermediate

P. Sharp, P. Grabowski, R. Padgett, 1984, Cell.

A multicomponent complex is involved in the splicing of messenger RNA precursors

Phillip A. Sharp, P. Sharp, P. Grabowski, 1985, Cell.

Characterization of the branch site in lariat RNAs produced by splicing of mRNA precursors

P. Sharp, P. Grabowski, R. Padgett, 1985, Nature.

Spliceosome assembly involves the binding and release of U4 small nuclear ribonucleoprotein.

P. Sharp, P. Grabowski, A. Lamond, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Splicing Decisions Shape Neuronal Protein Function across the Transcriptome

P. Grabowski, Jill A. Dembowski, 2013 .

Evidence for Direct Roles of Two Additional Factors, SECp43 and Soluble Liver Antigen, in the Selenoprotein Synthesis Machinery*

P. Grabowski, V. Gladyshev, B. Carlson, 2005, Journal of Biological Chemistry.

Autocatalytic cyclization of an excised intervening sequence RNA is a cleavage–ligation reaction

T. Cech, P. Grabowski, A. Zaug, 1983, Nature.

Splicing Regulation in Neurons: Tinkering with Cell-Specific Control

P. Grabowski, 1998, Cell.

Identification of a protein component of a mammalian tRNA(Sec) complex implicated in the decoding of UGA as selenocysteine.

P. Grabowski, F. Ding, 1999, RNA.

The CUGBP2 Splicing Factor Regulates an Ensemble of Branchpoints from Perimeter Binding Sites with Implications for Autoregulation

P. Grabowski, Jill A. Dembowski, 2009, PLoS genetics.

Region-specific alternative splicing in the nervous system: implications for regulation by the RNA-binding protein NAPOR.

P. Grabowski, Kyoungha Han, Haiying Liu, 2002, RNA.

RNA-binding proteins switch gears to drive alternative splicing in neurons

P. Grabowski, 2007, Nature Structural &Molecular Biology.

A Combinatorial Code for Splicing Silencing: UAGG and GGGG Motifs

Gene W. Yeo, Ping An, C. Burge, 2005, PLoS biology.

A molecular code for splicing silencing: configurations of guanosine-rich motifs.

P. Grabowski, 2004, Biochemical Society transactions.

Coordinate repression of a trio of neuron-specific splicing events by the splicing regulator PTB.

P. Grabowski, W. Liu, L. Zhang, 1999, RNA.

Essential nucleotides direct neuron-specific splicing of gamma 2 pre-mRNA.

M. Ashiya, P. Grabowski, T. Sherman, 1996, RNA.

Genetic Evidence for a Nova Regulator of Alternative Splicing in the Brain

P. Grabowski, 2000, Neuron.

Splicing of messenger RNA precursors.

P. Sharp, P. Grabowski, A. Lamond, 1987, Cold Spring Harbor symposia on quantitative biology.

Alternative splicing in parallel

P. Grabowski, Paula Grabowski, 2002, Nature Biotechnology.

Cell- and stage-specific splicing events resolved in specialized neurons of the rat cerebellum.

P. Grabowski, Z. Wang, P J Grabowski, 1996, RNA.

Intrinsic U2AF binding is modulated by exon enhancer signals in parallel with changes in splicing activity.

P. Grabowski, Z. Wang, H. Hoffmann, 1995, RNA.

Mutations in RRM4 uncouple the splicing repression and RNA-binding activities of polypyrimidine tract binding protein.

P. Grabowski, R. B. Reed, Haiying Liu, 2002, RNA.

Splicing of messenger RNA precursors.

P. Sharp, P. Grabowski, R. Padgett, 1987, Annual Review of Biochemistry.

Splicing error in E1alpha pyruvate dehydrogenase mRNA caused by novel intronic mutation responsible for lactic acidosis and mental retardation.

Marc Abitbol, P. Grabowski, G. Touati, 2003, The Journal of biological chemistry.

Splicing of messenger RNA precursors.

P. Sharp, P. Grabowski, R. Padgett, 1985, Harvey lectures.