S. Buus

O. Lund, M. Nielsen, S. Buus, 2010, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

MHC-I-restricted epitopes conserved among variola and other related orthopoxviruses are recognized by T cells 30 years after vaccination

O. Lund, K. Lamberth, S. Buus, 2008, Archives of Virology.

Activating Polyfunctional CD8+ T Cells in Mycobacterium tuberculosis Antigens Genome-Based In Silico Identification of New

O. Lund, S. Buus, U. Şahin, 2013 .

Genome-Based In Silico Identification of New Mycobacterium tuberculosis Antigens Activating Polyfunctional CD8+ T Cells in Human Tuberculosis

Ole Lund, Ugur Sahin, Søren Buus, 2011, The Journal of Immunology.

Human Tuberculosis T Cells in + Activating Polyfunctional CD 8 Antigens Mycobacterium tuberculosis Genome-Based In Silico Identification of New Ottenhoff

O. Lund, S. Buus, U. Şahin, 2010 .

Shared peptide binding of HLA Class I and II alleles associate with cutaneous nevirapine hypersensitivity and identify novel risk alleles

M. Carrington, S. Mallal, Bjoern Peters, 2017, Scientific Reports.

A recombinant antibody with the antigen-specific, major histocompatibility complex-restricted specificity of T cells.

P. S. Andersen, S. Buus, L. Fugger, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Identification of a Novel UTY‐Encoded Minor Histocompatibility Antigen

O. Lund, S. Buus, M. Harndahl, 2012, Scandinavian journal of immunology.

Sequencing swine leucocyte alleles for vaccine development

M. Nielsen, S. Buus, R. Bishop, 2018 .

Peptide-loaded dendritic cells prime and activate MHC-class I-restricted T cells more efficiently than protein-loaded cross-presenting DC.

S. Buus, M. Claesson, O. Met, 2003, Cellular immunology.

Immunoinformatics: Predicting Peptide-MHC Binding.

Morten Nielsen, Bjoern Peters, Massimo Andreatta, 2020, Annual review of biomedical data science.

Identification and Mapping of Linear Antibody Epitopes in Human Serum Albumin Using High-Density Peptide Arrays

S. Buus, C. Schafer‐Nielsen, Lajla Bruntse Hansen, 2013, PloS one.

High-resolution Mapping of Linear Antibody Epitopes Using Ultrahigh-density Peptide Microarrays*□S

S. Buus, Björn Forsström, M. Uhlén, 2012 .

Establishing the pig as a large animal model for vaccine development against human cancer

S. Buus, M. Rasmussen, G. Jungersen, 2015, Front. Genet..

Quantitative predictions of peptide binding to MHC class I molecules using specificity matrices and anchor-stratified calibrations.

S Brunak, S L Lauemøller, S. Brunak, 2001, Tissue antigens.

SARS CTL vaccine candidates; HLA supertype‐, genome‐wide scanning and biochemical validation

S. Brunak, M. Nielsen, O. Lund, 2004, Tissue antigens.

Efficient Induction of T Cells against Conserved HIV-1 Regions by Mosaic Vaccines Delivered as Self-Amplifying mRNA

S. Buus, U. Şahin, T. Hanke, 2018, Molecular therapy. Methods & clinical development.

The peptide-binding specificity of HLA-A*3001 demonstrates membership of the HLA-A3 supertype

Morten Nielsen, Ole Lund, Claus Lundegaard, 2008, Immunogenetics.

Identification of CD8+ T Cell Epitopes in the West Nile Virus Polyprotein by Reverse-Immunology Using NetCTL

Morten Nielsen, Ole Lund, Søren Buus, 2010, PloS one.

In silico-accelerated identification of conserved and immunogenic variola/vaccinia T-cell epitopes.

Julie A McMurry, Sharon Frey, Leonard Moise, 2009, Vaccine.

Diversity of Francisella tularensis Schu4 antigens recognized by T lymphocytes after natural infections in humans: identification of candidate epitopes for inclusion in a rationally designed tularemia vaccine.

Julie A McMurry, Leonard Moise, Anne S De Groot, 2007, Vaccine.

NNAlign_MA; semi-supervised MHC peptidome deconvolution for accurate characterization of MHC binding motifs and improved T cell epitope prediction

Massimo Andreatta, Morten Nielsen, Bruno Alvarez, 2019 .

Extraordinary peptide-binding mode of a songbird MHC class-I molecule suggests mechanism to counter pathogen immune evasion

M. Nielsen, S. Buus, K. Lindkvist-Petersson, 2023, bioRxiv.

A modern approach for epitope prediction: identification of foot-and-mouth disease virus peptides binding bovine leukocyte antigen (BoLA) class I molecules

M. Nielsen, S. Buus, M. Rasmussen, 2015, Immunogenetics.

Characterization of binding specificities of bovine leucocyte class I molecules: impacts for rational epitope discovery

Morten Nielsen, Søren Buus, Mikkel Harndahl, 2014, Immunogenetics.

Transgenic/H-2 Class I Null Mice: Novel Versatile Preclinical Models of Human T Cell Responses

Tanja, S. Buus, F. Lemonnier, 2014 .

HLA-A*01:03, HLA-A*24:02, HLA-B*08:01, HLA-B*27:05, HLA-B*35:01, HLA-B*44:02, and HLA-C*07:01 Monochain Transgenic/H-2 Class I Null Mice: Novel Versatile Preclinical Models of Human T Cell Responses

S. Buus, L. BenMohamed, F. Lemonnier, 2013, The Journal of Immunology.

ResponsesPreclinical Models of Human T Cell Transgenic/H-2 Class I Null Mice: Novel and HLA-C*07:01 Monochain HLA-B*27:05, HLA-B*35:01, HLA-B*44:02, HLA-A*01:03, HLA-A*24:02, HLA-B*08:01,

S. Buus, A. Lim, M. Bérard, 2013 .

Responses Versatile Preclinical Models of Human T Cell Hla-a*01:03, Hla-a*24:02, Hla-b*08:01

S. Buus, L. BenMohamed, F. Lemonnier, 2022 .

The Immune Epitope Database and Analysis Resource

Philip E. Bourne, John Sidney, Huynh-Hoa Bui, 2006, PRIB.

Relative contribution of "determinant selection" and "holes in the T-cell repertoire" to T-cell responses.

M. Bekoff, H. Grey, A. Sette, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Peptide-MHC class I stability is a stronger predictor of CTL immunogenicity than peptide affinity

M. Nielsen, S. Buus, M. Harndahl, 2012 .

NetMHCIIpan-3.0, a common pan-specific MHC class II prediction method including all three human MHC class II isotypes, HLA-DR, HLA-DP and HLA-DQ

O. Lund, M. Nielsen, S. Buus, 2013, Immunogenetics.

Tumor‐associated antigens identified by mRNA expression profiling induce protective anti‐tumor immunity

Søren Buus, Morten Ruhwald, S. Buus, 2001, European journal of immunology.

Immunogenicity of HLA Class I and II Double Restricted Influenza A-Derived Peptides

S. R. Pedersen, M. Nielsen, S. Buus, 2016, PloS one.

A combined prediction strategy increases identification of peptides bound with high affinity and stability to porcine MHC class I molecules SLA-1*04:01, SLA-2*04:01, and SLA-3*04:01

M. Nielsen, S. Buus, M. Harndahl, 2016, Immunogenetics.

HLA-Specific Intracellular Epitope Processing Shapes an Immunodominance Pattern for HLA-B*57 That Is Distinct from HLA-B*58:01

Greg J. Towers, Søren Buus, Mikkel Harndahl, 2013, Journal of Virology.

HLA-B7–Restricted Islet Epitopes Are Differentially Recognized in Type 1 Diabetic Children and Adults and Form Weak Peptide-HLA Complexes

S. Buus, G. Bruno, F. Lemonnier, 2012, Diabetes.

Porcine major histocompatibility complex (MHC) class I molecules and analysis of their peptide-binding specificities

Morten Nielsen, Ole Lund, Kasper Lamberth, 2011, Immunogenetics.

Tapasin Discriminates Peptide-Human Leukocyte Antigen-A*02:01 Complexes Formed with Natural Ligands*

G. Røder, S. Buus, M. Harndahl, 2011, The Journal of Biological Chemistry.

Identification of MHC class II restricted T‐cell‐mediated reactivity against MHC class I binding Mycobacterium tuberculosis peptides

O. Lund, S. Justesen, S. Buus, 2011, Immunology.

Longer peptide can be accommodated in the MHC class I binding site by a protrusion mechanism

Søren Buus, Anette Stryhn, S. Buus, 2000, European journal of immunology.

HLA class I is most tightly linked to levels of tapasin compared with other antigen-processing proteins in glioblastoma

S. Buus, M. Harndahl, K. Paulsson, 2015, British Journal of Cancer.

Structural requirements for the interaction between peptide antigens and I-Ed molecules.

L Adorini, G Doria, A Sette, 1989, Journal of immunology.

Capacity of intact proteins to bind to MHC class II molecules.

L Adorini, A Sette, H. Grey, 1989, Journal of immunology.

Biochemical analysis of peptide binding to MHC class I

S. Buus, A. Stryhn, L. Ostergaardpedersen, 1996 .

Structural requirements for the interaction between class II MHC molecules and peptide antigens

L Adorini, A Sette, H. Grey, 1990, Immunologic research.

Structural requirements and biological significance of interactions between peptides and the major histocompatibility complex.

H. Grey, A. Sette, S. Buus, 1989, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Structural Requirements of an Ovalbumin-Derived Immunogenic Peptide for T Cell Activation and Interaction with IAd

H. Grey, A. Sette, S. Buus, 1988 .

I-Ad-binding peptides derived from unrelated protein antigens share a common structural motif.

H. Grey, A. Sette, S. Buus, 1988, Journal of immunology.

Identification of a nonameric H-2Kk-restricted CD8+ cytotoxic T lymphocyte epitope on the Plasmodium falciparum circumsporozoite protein

S. Hoffman, J. Berzofsky, S. Buus, 1995, Infection and immunity.

Interaction of an immunodominant epitope with Ia molecules in T-cell activation.

L Adorini, G Doria, A Sette, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Role of the T Cell Receptor Ligand Affinity in T Cell Activation by Bacterial Superantigens*

Søren Buus, S. Buus, C. Geisler, 2001, The Journal of Biological Chemistry.

Low antigen dose formulated in CAF09 adjuvant Favours a cytotoxic T-cell response following intraperitoneal immunization in Göttingen minipigs.

S. Buus, G. Jungersen, T. M. Frøsig, 2017, Vaccine.

Comparison of Vaccine-Induced Effector CD8 T Cell Responses Directed against Self- and Non–Self-Tumor Antigens: Implications for Cancer Immunotherapy

S. R. Pedersen, S. Buus, J. Christensen, 2013, The Journal of Immunology.

Humoral and Cellular CMV Responses in Healthy Donors; Identification of a Frequent Population of CMV-Specific, CD4+ T Cells in Seronegative Donors

S. Buus, A. Stryhn, H. Madsen, 2012, PloS one.

Programmed death-1 expression on HIV-1-specific CD8+ T cells is shaped by epitope specificity, T-cell receptor clonotype usage and antigen load

P. Klenerman, S. Buus, P. Goulder, 2014, AIDS.

Immune hierarchy among HIV-1 CD8+ T cell epitopes delivered by dendritic cells depends on MHC-I binding irrespective of mode of loading and immunization in HLA-A*0201 mice

S. Buus, A. Fomsgaard, I. Karlsson, 2009, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

Identification of peptides from foot-and-mouth disease virus structural proteins bound by class I swine leukocyte antigen (SLA) alleles, SLA-1*0401 and SLA-2*0401.

M. Nielsen, S. Buus, M. Harndahl, 2013, Animal genetics.

Structure of HLA-A*1101 in complex with a hepatitis B peptide homologue.

S. Buus, T. Blicher, L. Pedersen, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

High‐resolution structure of HLA‐A*1101 in complex with SARS nucleocapsid peptide

S. Buus, T. Blicher, J. Kastrup, 2005, Acta crystallographica. Section D, Biological crystallography.

MHC Class I Epitope Binding Prediction Trained on Small Data Sets

Søren Brunak, Morten Nielsen, Ole Lund, 2004, ICARIS.

Selecting Informative Data for Developing Peptide-MHC Binding Predictors Using a Query by Committee Approach

Søren Brunak, Morten Nielsen, Ole Lund, 2003, Neural Computation.

High‐affinity human leucocyte antigen class I binding variola‐derived peptides induce CD4+ T cell responses more than 30 years post‐vaccinia virus vaccination

O. Lund, S. Buus, M. Claesson, 2009, Clinical and experimental immunology.

Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity

H. Ullum, S. Buus, M. Skrzypczak, 2021, Nature Communications.

Personalized adoptive immunotherapy for patients with EBVassociated tumors and complications

S. Buus, R. Blasczyk, B. Maecker-Kolhoff, 2018 .

Chaperone-assisted thermostability engineering of a soluble T cell receptor using phage display

S. Justesen, S. Buus, Kristin S. Gunnarsen, 2013, Scientific Reports.

Effect of conformational propensity of peptide antigens in their interaction with MHC class II molecules. Failure to document the importance of regular secondary structures.

A Sette, H. Grey, A. Sette, 1989, Journal of immunology.

Expanding specificity of class I restricted CD8+ T cells for viral epitopes following multiple inoculations of swine with a human adenovirus vectored foot-and-mouth disease virus (FMDV) vaccine.

M. Nielsen, S. Buus, L. E. Pedersen, 2016, Veterinary immunology and immunopathology.

Food intake and nutritional status after gastrectomy.

S. Buus, I. Hessov, S. Bisballe, 1986, Human nutrition. Clinical nutrition.

Thiopurine 6TG treatment increases tumor immunogenicity and response to immune checkpoint blockade

M. Nielsen, S. Buus, C. Bertolotto, 2022, Oncoimmunology.

Materno-Fetal Transfer of Preproinsulin Through the Neonatal Fc Receptor Prevents Autoimmune Diabetes

N. Gupta, S. Justesen, S. Buus, 2015, Diabetes.

High levels of antibodies 6 months after COVID‐19 vaccination in children with severe chronic diseases: A prospective longitudinal case series

S. Buus, K. Nielsen, L. Stensballe, 2023, Acta paediatrica.

A novel system for continuous protein refolding and on‐line capture by expanded bed adsorption

Søren Buus, S. Buus, O. Thomas, 2005, Protein science : a publication of the Protein Society.

Efficient Control of Zika Virus Infection Induced by a Non-Replicating Adenovector Encoding Zika Virus NS1/NS2 Antigens Fused to the MHC Class II-Associated Invariant Chain

S. Buus, J. Christensen, A. Stryhn, 2021, Viruses.

Adaptive immune responses to booster vaccination against yellow fever virus are much reduced compared to those after primary vaccination

S. Buus, J. Christensen, A. Stryhn, 2017, Scientific Reports.

Antibodies to native gluten arise from cross-reactive B cells with implications for epitope spreading in celiac disease

S. Buus, K. Lundin, J. Jahnsen, 2022, bioRxiv.

Bjoern Peters, S. Buus, Yohan Kim, 2013, Malaria Journal.

Peptides Derived From Insulin Granule Proteins Are Targeted by CD8+ T Cells Across MHC Class I Restrictions in Humans and NOD Mice

S. Buus, G. Bruno, D. Eizirik, 2020, Diabetes.

Dataset size and composition impact the reliability of performance benchmarks for peptide-MHC binding predictions

M. Nielsen, Bjoern Peters, J. Sidney, 2014, BMC Bioinformatics.

Gene SAG 1 Immunized with a Plasmid Encoding the Infection in Mice Toxoplasma gondii Complete Protection against Lethal

S. Buus, S. Lauemøller, A. Fomsgaard, 1999 .

A New In Vivo Model to Study Protective Immunity to Zika Virus Infection in Mice With Intact Type I Interferon Signaling

S. Buus, J. Christensen, A. Stryhn, 2018, Front. Immunol..

The structure of songbird MHC class I reveals antigen binding that is flexible at the N-terminus and static at the C-terminus

M. Nielsen, S. Buus, K. Lindkvist-Petersson, 2023, Frontiers in immunology.

Access the most recent version at doi: 10.1110/ps.0239403 References

O. Lund, S. Brunak, C. Lundegaard, 2002 .

Sensitive quantitative predictions of peptide-MHC binding by a 'Query by Committee' artificial neural network approach.

S Brunak, S Buus, S L Lauemøller, 2003, Tissue antigens.

Translational Immunology: from vaccines to immunotherapy

G. Røder, S. Buus, M. Harndahl, 2010 .

Treatment of transplanted CT26 tumour with dendritic cell vaccine in combination with blockade of vascular endothelial growth factor receptor 2 and CTLA-4.

S. Buus, M. Claesson, A. Pedersen, 2006, Cancer letters.

Reliable prediction of T‐cell epitopes using neural networks with novel sequence representations

O. Lund, S. Brunak, C. Lundegaard, 2003, Protein science : a publication of the Protein Society.

Differential Immunodominance Hierarchy of CD8 (cid:2) T-Cell Responses in HLA-B * 27:05- and -B * 27:02-Mediated Control of HIV-1 Infection

B. Walker, M. John, S. Mallal, 2018 .

Differential Immunodominance Hierarchy of CD8 (cid:2) T-Cell Responses in HLA-B * 27:05- and -B * 27:02-Mediated Control of HIV-1 Infection

B. Walker, M. John, S. Mallal, 2018 .

HIV control through a single nucleotide on the HLA-I locus

T. Ndung’u, S. Buus, M. Harndahl, 2012, Journal of Virology.

Competition of Chemically Related Antigens for Presentation by Accessory Cells to T Cells Requires Expenditure of Metabolic Energy by the Accessory Cells

S. Buus, S. Buus, O. Werdelin, 1983, Scandinavian journal of immunology.

Purification of correctly oxidized MHC class I heavy‐chain molecules under denaturing conditions: A novel strategy exploiting disulfide assisted protein folding

C. Sylvester-Hvid, S. Buus, T. Blicher, 2003, Protein science : a publication of the Protein Society.

Complete dissection of the Hb(64-76) determinant using T helper 1, T helper 2 clones, and T cell hybridomas.

S. Buus, P. Allen, B. Evavold, 1992, Journal of immunology.

Accurate pan-specific prediction of peptide-MHC class II binding affinity with improved binding core identification

M. Nielsen, S. Buus, M. Andreatta, 2015, Immunogenetics.

HIV-specific CD8+ T-cells in tonsils express exhaustive TRM-like signatures

T. Ndung’u, S. Kazer, A. Shalek, 2021, bioRxiv.

MHC molecules protect T cell epitopes against proteolytic destruction.

S. Buus, M. Meldal, S. Buus, 1992, Journal of immunology.

HLA-A*68: 02-restricted Gag-specific cytotoxic T lymphocyte responses can drive selection pressure on HIV but are subdominant and ineffective

B. Walker, T. Ndung’u, S. Buus, 2013, AIDS.

Coxsackievirus infection induces direct pancreatic β-cell killing but poor anti-viral CD8+ T-cell responses

S. Tuomela, S. Buus, R. Scharfmann, 2023, bioRxiv.

Conservation of HIV-1 T cell epitopes across time and clades: validation of immunogenic HLA-A2 epitopes selected for the GAIA HIV vaccine

S. Buus, A. D. De Groot, O. Koita, 2012, Retrovirology.

Identification of peptides from foot-and-mouth disease virus structural proteins bound by class I swine leukocyte antigen (SLA) alleles, SLA-1*0401 and SLA-2*0401.

S. Buus, M. Harndahl, L. E. Pedersen, 2013, Animal genetics.

Elimination of Immunodominant Epitopes from Multispecific DNA-Based Vaccines Allows Induction of CD8 T Cells That Have a Striking Antiviral Potential1

K. Lamberth, S. Buus, F. Lemonnier, 2009, The Journal of Immunology.

Interaction between Protein-Derived Immunogenic Peptides and Ia

H. Grey, S. Buus, 1986 .

Low antigen dose formulated in CAF09 adjuvant Favours a cytotoxic T-cell response following intraperitoneal immunization in Göttingen minipigs.

S. Buus, G. Jungersen, T. M. Frøsig, 2017, Vaccine.

Lauemøller Identifying cytotoxic T cell epitopes from C . Kesmir genomic and proteomic information :

Holm, S. Brunak, S. Buus, 2022 .

Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance

P. Klenerman, K. Lamberth, S. Buus, 2009, Nature Immunology.

ArrayPitope: Automated Analysis of Amino Acid Substitutions for Peptide Microarray-Based Antibody Epitope Mapping

Morten Nielsen, Ole Lund, Paolo Marcatili, 2017, PloS one.

A combined prediction strategy increases identification of peptides bound with high affinity and stability to porcine MHC class I molecules SLA-1*04:01, SLA-2*04:01, and SLA-3*04:01

M. Nielsen, S. Buus, M. Harndahl, 2015, Immunogenetics.

Identification of peptides from foot-and-mouth disease virus structural proteins bound by class I swine leukocyte antigen (SLA) alleles, SLA-1*0401 and SLA-2*0401.

S. Buus, M. Harndahl, L. E. Pedersen, 2013, Animal genetics.

Peptide specific expansion of CD8(+) T cells by recombinant plate bound MHC/peptide complexes.

S. Buus, A. Stryhn, M. Claesson, 2009, Journal of immunological methods.

Uncovering the Peptide-Binding Specificities of HLA-C: A General Strategy To Determine the Specificity of Any MHC Class I Molecule

M. Nielsen, S. Buus, M. Harndahl, 2014, The Journal of Immunology.

HLA-A*01:03, HLA-A*24:02, HLA-B*08:01, HLA-B*27:05, HLA-B*35:01, HLA-B*44:02, and HLA-C*07:01 Monochain Transgenic/H-2 Class I Null Mice: Novel Versatile Preclinical Models of Human T Cell Responses

S. Buus, L. BenMohamed, F. Lemonnier, 2013, The Journal of Immunology.

Soluble Human Leukocyte Antigen‐G in Seminal Plasma is Associated with HLA‐G Genotype: Possible Implications for Fertility Success

S. Buus, T. Hviid, A. Lindhard, 2014, American journal of reproductive immunology.

Pan-Specific Prediction of Peptide–MHC Class I Complex Stability, a Correlate of T Cell Immunogenicity

M. Nielsen, S. Buus, M. Harndahl, 2016, The Journal of Immunology.