A. McQuillin

A. McQuillin, N. Bass, D. Curtis, 2019, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Identification of rare nonsynonymous variants in SYNE1/CPG2 in bipolar affective disorder

A. McQuillin, N. Bass, R. Kandaswamy, 2017, Psychiatric genetics.

Genetic association, mutation screening, and functional analysis of a Kozak sequence variant in the metabotropic glutamate receptor 3 gene in bipolar disorder.

H. Gurling, A. McQuillin, D. Curtis, 2013, JAMA psychiatry.

A novel polymorphism in exon 11 of the WKL1 gene, shows no association with schizophrenia

H. Gurling, A. McQuillin, D. Quested, 2002, European Journal of Human Genetics.

Genetic association studies of schizophrenia using the 8p21-22 genes: prepronociceptin (PNOC), neuronal nicotinic cholinergic receptor alpha polypeptide 2 (CHRNA2) and arylamine N-acetyltransferase 1 (NAT1)

David Curtis, Andrew McQuillin, Jacob Lawrence, 2001, European Journal of Human Genetics.

Fine Mapping by Genetic Association Implicates the Chromosome 1q23.3 Gene UHMK1, Encoding a Serine/Threonine Protein Kinase, as a Novel Schizophrenia Susceptibility Gene

H. Gurling, A. McQuillin, K. Choudhury, 2007, Biological Psychiatry.

Genetic association and brain morphology studies and the chromosome 8p22 pericentriolar material 1 (PCM1) gene in susceptibility to schizophrenia.

David Curtis, Khalid Choudhury, Andrew McQuillin, 2006, Archives of general psychiatry.

Failure to confirm genetic association between schizophrenia and markers on chromosome 1q23.3 in the region of the gene encoding the regulator of G‐protein signaling 4 protein (RGS4)

H. Gurling, A. McQuillin, K. Choudhury, 2006, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

The Epsin 4 gene on chromosome 5q, which encodes the clathrin-associated protein enthoprotin, is involved in the genetic susceptibility to schizophrenia.

David Curtis, Andrew McQuillin, Srinivasa Thirumalai, 2005, American journal of human genetics.

Evidence for the association of the DAOA (G72) gene with schizophrenia and bipolar disorder but not for the association of the DAO gene with schizophrenia

A. McQuillin, K. Choudhury, J. Pimm, 2009, Behavioral and Brain Functions.

Confirmation of the genetic association between the U2AF homology motif (UHM) kinase 1 (UHMK1) gene and schizophrenia on chromosome 1q23.3

C. Crombie, G. Fraser, N. Walker, 2008, European Journal of Human Genetics.

Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia.

Leena Peltonen, Andrew McQuillin, Jouko Lönnqvist, 2003, American journal of human genetics.

Genetic overlap between Attention-Deficit / Hyperactivity Disorder and Bipolar Disorder : Evidence from GWAS meta-analysis

B. Franke, O. Andreassen, J. Kelsoe, 2017 .

A polygenic risk score analysis of psychosis endophenotypes across brain functional, structural, and cognitive domains

D. Rujescu, E. Bramon, R. Murray, 2017, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Whole-exome sequencing of individuals from an isolated population implicates rare risk variants in bipolar disorder

August G. Wang, J. Wang, L. Bolund, 2017, Translational Psychiatry.

MUTATIONS IN THE GABRB1 GENE PROMOTE ALCOHOL CONSUMPTION THROUGH INCREASED TONIC INHIBITION

Alastair M. Hosie, Jimmy D Bell, E. Fisher, 2013, Nature Communications.

Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

N. Wray, D. Rujescu, S. Cichon, 2018, bioRxiv.

Mutation intolerant genes and targets of FMRP are enriched for nonsynonymous alleles in schizophrenia

M. Owen, M. O’Donovan, P. Sullivan, 2017, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

John P. Rice, Melissa J. Green, Robert C. Thompson, 2017, Cell.

The functional GRM3 Kozak sequence variant rs148754219 affects the risk of schizophrenia and alcohol dependence as well as bipolar disorder

D. Ball, A. McQuillin, D. Quested, 2014, Psychiatric genetics.

Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity

Tom R. Gaunt, Thomas M. Keane, Hashem A. Shihab, 2017, Scientific Reports.

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

John P. Rice, Melissa J. Green, Robert C. Thompson, 2017, Cell.

Characterisation of age and polarity at onset in bipolar disorder

Till F. M. Andlauer, S. Cichon, S. Djurovic, 2021, The British Journal of Psychiatry.

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

Hunna J. Watson, James E. Mitchell, Melissa J. Green, 2020, medRxiv.

22 . 1-11 . 2 and 1 q 21 . 3-24 . 2

A. McQuillin, D. Curtis, H. Gurling, 2015 .

Genetic linkage analysis supports the presence of two susceptibility loci for alcoholism and heavy drinking on chromosome 1p22.1-11.2 and 1q21.3-24.2

A. McQuillin, D. Curtis, H. Gurling, 2005, BMC Genetics.

Variation in the DCP1 gene, encoding the angiotensin converting enzyme ACE, is not associated with increased susceptibility to Alzheimer's disease

G. Livingston, C. Katona, A. McQuillin, 2003, Psychiatric genetics.

Meta-analysis of genetic association with diagnosed Alzheimer’s disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing

J. Gallacher, M. Fornage, I. Giegling, 2018, bioRxiv.

Universitet Low-frequency variation in TP 53 has large effects on head circumference and intracranial

Tom R. Gaunt, Thomas M. Keane, Hashem A. Shihab, 2019 .

Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

Tom R. Gaunt, Hashem A. Shihab, Gail P. Clement, 2018, bioRxiv.

A microarray gene expression study of the molecular pharmacology of lithium carbonate on mouse brain mRNA to understand the neurobiology of mood stabilization and treatment of bipolar affective disorder

H. Gurling, A. McQuillin, M. Rizig, 2007, Pharmacogenetics and genomics.

How data science can advance mental health research (Forthcoming)

Zina M. Ibrahim, R. Dobson, A. McIntosh, 2018 .

Rare variant analysis in multiply affected families, association studies and functional analysis suggest a role for the ITGΒ4 gene in schizophrenia and bipolar disorder

A. McQuillin, N. Bass, D. Curtis, 2018, Schizophrenia Research.

Genetic variants in PNPLA3 and TM6SF2 predispose to the development of hepatocellular carcinoma in individuals with alcohol‐related cirrhosis

F. Lammert, J. Hampe, A. McQuillin, 2018, The American Journal of Gastroenterology.

Correction: Genetic Variants in PNPLA3 and TM6SF2 Predispose to the Development of Hepatocellular Carcinoma in Individuals With Alcohol-Related Cirrhosis

A. McQuillin, H. Nischalke, S. Buch, 2018, The American Journal of Gastroenterology.

Genetic variation in TERT modifies the risk of hepatocellular carcinoma in alcohol-related cirrhosis: results from a genome-wide case-control study

M. Rietschel, C. Datz, C. Strassburg, 2022, Gut.

Replication of genetic association studies between markers at the Epsin 4 gene locus and schizophrenia in two Han Chinese samples

H. Gurling, A. McQuillin, J. Pimm, 2007, Schizophrenia Research.

Gene brain structure relationships: arbitrary assumptions of heterogeneity generate unfalsifiable claims.

Richard S. J. Frackowiak, A. Malhotra, H. Critchley, 2007 .

A gene expression and systems pathway analysis of the effects of clozapine compared to haloperidol in the mouse brain implicates susceptibility genes for schizophrenia

M. Zvelebil, H. Gurling, A. McQuillin, 2012, Journal of psychopharmacology.

Multi-ancestry GWAS of major depression aids locus discovery, fine-mapping, gene prioritisation, and causal inference

Dan J Stein, N. Wray, R. Kessler, 2022, bioRxiv.

Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders

Minna Männikkö, David Curtis, Peter Holmans, 2016, Nature Neuroscience.

Heterozygous carriage of the alpha1-antitrypsin Pi*Z variant increases the risk to develop liver cirrhosis

M. Rietschel, C. Datz, C. Trautwein, 2018, Gut.

Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Nick C Fox, Michelle K. Lupton, Charles C. White, 2019, Nature Genetics.

Reply to: "The PNPLA3 SNP rs738409:G allele is associated with increased liver disease-associated mortality but reduced overall mortality in a population-based cohort".

A. McQuillin, M. Morgan, S. Atkinson, 2017, Journal of hepatology.

Response to: The PNPLA3 SNP rs738409:G allele is associated with increased liver disease-associated mortality but reduced overall mortality in a population-based cohort

A. McQuillin, M. Morgan, S. Atkinson, 2018 .

Title: High rates of neurodevelopmental risk CNVs in patients with intellectual disabilities and co-morbid psychiatric disorders Running title: High rates of CNVs in ID with psychiatric disorder Byline:

J. Vermeesch, A. McQuillin, N. Baena, 2018 .

Novel Biological Insights Into the Common Heritable Liability to Substance Involvement: A Multivariate Genome-wide Association Study

Z. Kutalik, A. McQuillin, N. Pirastu, 2022, Biological Psychiatry.

The communication of metacognition for social strategy in psychosis: an exploratory study

B. Bahrami, A. McQuillin, Uri Hertz, 2020, Schizophrenia Bulletin Open.

Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis

Tom R. Gaunt, Thomas M. Keane, Hashem A. Shihab, 2019, Nature Communications.

A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans

Gail Clement, Jie Huang, Antonio Ciampi, 2014, Nature Communications.

Memory Decline in Down Syndrome and Its Relationship to iPF2alpha, a Urinary Marker of Oxidative Stress

A. McQuillin, D. Praticò, Z. Walker, 2014, PloS one.

SLC19A1 Genetic Variation Leads to Altered Thiamine Diphosphate Transport: Implications for the Risk of Developing Wernicke-Korsakoff's Syndrome.

A. McQuillin, N. Bass, I. Smith, 2022, Alcohol and alcoholism.

The differential associations of positive and negative symptoms with suicidality

A. McQuillin, N. Bass, Rebecca Jones, 2022, Schizophrenia Research.

A nonconservative amino acid change in the UPF3B gene in a patient with schizophrenia.

H. Gurling, A. McQuillin, P. Szyszka, 2012, Psychiatric genetics.

Adjacent genetic markers on chromosome 11p15.5 at or near the tyrosine hydroxylase locus that show population linkage disequilibrium with each other do not show allelic association with bipolar affective disorder

A. McQuillin, J. Lawrence, D. Curtis, 1999, Psychological Medicine.

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease (vol 41, pg 1088, 2009)

Nick C Fox, Moskvina, D. Rujescu, 2013 .

Genetic testing in intellectual disability psychiatry: Opinions and practices of UK child and intellectual disability psychiatrists

A. McQuillin, N. Bass, C. Patch, 2017, Journal of applied research in intellectual disabilities : JARID.

Genetic risk scores and dementia risk across different ethnic groups in UK Biobank

A. McQuillin, N. Mukadam, K. Kuchenbaecker, 2022, PloS one.

Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

Tom R. Gaunt, Thomas M. Keane, Hashem A. Shihab, 2018, bioRxiv.

No association between a neuronal nitric oxide synthase (NOS1) gene polymorphism on chromosome 12q24 and bipolar disorder

A. McQuillin, J. Lawrence, O. Mors, 2004, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

No evidence for excess runs of homozygosity in bipolar disorder

P. Sklar, H. Gurling, A. McQuillin, 2009, Psychiatric genetics.

Genetic variation in HSD17B3 reduces the risk for developing severe alcoholic hepatitis

A. McQuillin, M. Morgan, S. Atkinson, 2020, Journal of Hepatology.

The effect of clozapine on mRNA expression for genes encoding G protein-coupled receptors and the protein components of clathrin-mediated endocytosis

S. Hunt, H. Gurling, A. McQuillin, 2013, Psychiatric genetics.

Does rare matter? Copy number variants at 16p11.2 and the risk of psychosis: A systematic review of literature and meta-analysis

A. McQuillin, N. Bass, G. Giaroli, 2014, Schizophrenia Research.

Meta-analysis of 32 genome-wide linkage studies of schizophrenia

E M Wijsman, G Kalsi, T Sigmundsson, 2009, Molecular Psychiatry.

Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel

Tom R. Gaunt, Klaudia Walter, Nicholas J Timpson, 2015, Nature Communications.

Evidence for genetic susceptibility to the alcohol dependence syndrome from the thiamine transporter 2 gene solute carrier SLC19A3

D. Ball, H. Gurling, A. McQuillin, 2014, Psychiatric genetics.

Direct genomic PCR sequencing of the high affinity thiamine transporter (SLC19A2) gene identifies three genetic variants in Wernicke Korsakoff syndrome (WKS)

A. McQuillin, M. Kopelman, A. Thomson, 2005, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology

Dan J Stein, Melissa J. Green, Janice M. Fullerton, 2021, Nature Genetics.

Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders

Hunna J. Watson, Ryan L. Collins, Dan J Stein, 2019, bioRxiv.

Genetic variation in the miR‐708 gene and its binding targets in bipolar disorder

A. McQuillin, N. Bass, D. Curtis, 2016, Bipolar disorders.

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

Laura J. Scott, Naomi R. Wray, Margaret A. Pericak-Vance, 2015, Nature Neuroscience.

Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1

P. Muglia, A. Noor, J. Vincent, 2014, BMC Medical Genetics.

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

Wei Cheng, Jianxin Shi, Elvira Bramon, 2016, Nature Genetics.

No allelic association between bipolar affective disorder and the tryptophan hydroxylase gene.

A. McQuillin, J. Lawrence, D. Curtis, 1998, Archives of general psychiatry.

GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia

D. Rujescu, S. Cichon, A. Ingason, 2011, Molecular Psychiatry.

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

Michael F. Green, Max W. Y. Lam, Catherine A. Sugar, 2022, Nature.

The genetics of the mood disorder spectrum: genome-wide association analyses of over 185,000 cases and 439,000 controls

Melissa J. Green, Robert C. Thompson, Pamela B. Mahon, 2018, bioRxiv.

Genome-wide association study identifies 30 Loci Associated with Bipolar Disorder

Melissa J. Green, Robert C. Thompson, Pamela B. Mahon, 2017, bioRxiv.

Ultra-rare genetic variation in the epilepsies: a whole-exome sequencing study of 17,606 individuals

Michael R. Johnson, S. Gabriel, M. Daly, 2019, bioRxiv.

Rare coding variants in ten genes confer substantial risk for schizophrenia

S. Gabriel, M. Daly, H. Kang, 2022, Nature.

A polygenic resilience score moderates the genetic risk for schizophrenia.

M. Pirinen, P. Donnelly, C. Spencer, 2019, Molecular psychiatry.

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Nick C Fox, Michelle K. Lupton, Charles C. White, 2019, Nature Genetics.

Behavioral and Brain Functions Failure to Confirm Allelic and Haplotypic Association between Markers at the Chromosome 6p22.3 Dystrobrevin-binding Protein 1 (dtnbp1) Locus and Schizophrenia

Kirwin, A. McQuillin, K. Choudhury, 2022 .

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

Hae Kyung Im, Solveig K Sieberts, Kiran Girdhar, 2019, Nature Genetics.

GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores.

N. Wray, D. Rujescu, S. Cichon, 2019, The American journal of psychiatry.

Exome sequencing in bipolar disorder identifies AKAP11 as a risk gene shared with schizophrenia

N. Freimer, R. Ophoff, D. Clair, 2022, Nature Genetics.

A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts

John P. Rice, Robert M. Maier, C. Spencer, 2020, Biological Psychiatry.

DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia

R. Murray, E. Vassos, D. Collier, 2021, eLife.

CACNA1C hypermethylation is associated with bipolar disorder

A. McQuillin, O. Mors, M. Nyegaard, 2016, Translational psychiatry.

Genome-wide Association Study of Clinical Features in the Schizophrenia Psychiatric Genomics Consortium: Confirmation of Polygenic Effect on Negative Symptoms

D. Rujescu, O. Andreassen, R. Ophoff, 2017, bioRxiv.

Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity

Tom R. Gaunt, Thomas M. Keane, Hashem A. Shihab, 2017, Scientific Reports.

Linkage disequilibrium and demographic history of the isolated population of the Faroe Islands

August G. Wang, A. McQuillin, O. Mors, 2002, European Journal of Human Genetics.

UK 10 K Consortium

Tom R. Gaunt, Hashem A. Shihab, Gail P. Clement, 2019 .

Genetic association of the tachykinin receptor 1 TACR1 gene in bipolar disorder, attention deficit hyperactivity disorder, and the alcohol dependence syndrome

S. Hunt, S. Stanford, H. Gurling, 2014, American Journal of Medical Genetics Part B: Neuropsychiatric Genetics.

Identifying risk factors involved in the common versus specific liabilities to substance use: A genetically informed approach

C. Cecil, A. McQuillin, E. Walton, 2020, Addiction biology.

Identifying risk factors involved in the common versus specific liabilities to substance use: A genetically informed approach

C. Cecil, A. McQuillin, E. Walton, 2019, bioRxiv.

Analysis of t(9;17)(q33.2;q25.3) chromosomal breakpoint regions and genetic association reveals novel candidate genes for bipolar disorder.

H. Gurling, A. McQuillin, Z. Tümer, 2015, Bipolar disorders.

The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease.

Thomas W. Mühleisen, Michelle K. Lupton, A. Singleton, 2012, Journal of Alzheimer's disease : JAD.

Neurodevelopmental risk copy number variants in adults with intellectual disabilities and comorbid psychiatric disorders

J. Vermeesch, A. McQuillin, N. Bass, 2018, British Journal of Psychiatry.

Chromosomal microarray testing in adults with intellectual disability presenting with comorbid psychiatric disorders

A. McQuillin, N. Bass, C. Patch, 2016, European Journal of Human Genetics.

Identification of the Slynar gene (AY070435) and related brain expressed sequences as a candidate gene for susceptibility to affective disorders through allelic and haplotypic association with bipolar disorder on chromosome 12q24.

A. McQuillin, K. Choudhury, V. Puri, 2006, The American journal of psychiatry.

Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder

Hoang T. Nguyen, G. Abecasis, H. Kang, 2021, Molecular Psychiatry.

EXOME SEQUENCING IN BIPOLAR DISORDER REVEALS SHARED RISK GENE AKAP11 WITH SCHIZOPHRENIA

R. Ophoff, N. Craddock, M. Owen, 2021, European Neuropsychopharmacology.

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

D. Rujescu, S. Cichon, I. Giegling, 2021, Biological Psychiatry.

Complement genes contribute sex-biased vulnerability in diverse illnesses

Simon C. Potter, Christopher W. Whelan, M. Pirinen, 2020, Nature.

Genetic copy number variants, cognition and psychosis: a meta-analysis and a family study

D. Rujescu, E. Bramon, R. Murray, 2020, Molecular Psychiatry.

Genetics of attention-deficit hyperactivity disorder (ADHD)

Andrew McQuillin, H. Gurling, A. McQuillin, 2009, Neuropharmacology.

Polygenic risk score-based phenome-wide association study identifies novel associations for Tourette syndrome

M. Daly, H. Stefánsson, R. Ophoff, 2022, Translational Psychiatry.

Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia

Thomas W. Mühleisen, N. Wray, D. Rujescu, 2017, Translational Psychiatry.

Genetic correlation between amyotrophic lateral sclerosis and schizophrenia

Denis C. Bauer, Annelot M. Dekker, Ashley R. Jones, 2017, Nature Communications.

New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis.

P. Visscher, N. Wray, M. Daly, 2015, International journal of epidemiology.

Elevated Common Variant Genetic Risk for Tourette Syndrome in a Densely Affected Pedigree

Michael Okun, H. Stefánsson, R. Ophoff, 2021, Molecular Psychiatry.

5 AN INTEGRATED GENETIC-EPIGENETIC ANALYSIS OF SCHIZOPHRENIA: EVIDENCE FOR CO-LOCALIZATION OF GENETIC ASSOCIATIONS AND DIFFERENTIAL DNA METHYLATION FROM A LARGE META-ANALYSIS OF WHOLE BLOOD DNA

D. Collier, D. Clair, G. Breen, 2019, European Neuropsychopharmacology.

Exome sequence analysis and follow up genotyping implicates rare ULK1 variants to be involved in susceptibility to schizophrenia

A. McQuillin, N. Bass, D. Curtis, 2017, Annals of human genetics.

Genetic variants in or near ADH1B and ADH1C affect susceptibility to alcohol dependence in a British and Irish population

D. Ball, A. McQuillin, D. Curtis, 2015, Addiction biology.

Genetic association study of GABRA2 single nucleotide polymorphisms and electroencephalography in alcohol dependence

D. Ball, A. McQuillin, I. Smith, 2011, Neuroscience Letters.

Fine mapping of a susceptibility locus for bipolar and genetically related unipolar affective disorders, to a region containing the C21ORF29 and TRPM2 genes on chromosome 21q22.3

A. McQuillin, K. Choudhury, V. Puri, 2006, Molecular Psychiatry.

Epigenetic age is accelerated in schizophrenia with age- and sex-specific effects and associated with polygenic disease risk

S. Horvath, R. Ophoff, P. Sullivan, 2019 .

Schizophrenia is characterized by age- and sex-specific effects on epigenetic aging

S. Horvath, R. Ophoff, A. McQuillin, 2019, bioRxiv.

Physical Health and Clinical Phenotypes

A. McQuillin, A. Strydom, Alexander Curmi, 2018, Physical Health of Adults with Intellectual and Developmental Disabilities.

Use of schizophrenia and bipolar disorder polygenic risk scores to identify psychotic disorders

D. Rujescu, E. Bramon, R. Murray, 2018, The British Journal of Psychiatry.

An inherited duplication at the gene p21 Protein-Activated Kinase 7 (PAK7) is a risk factor for psychosis

Bradley P. Coe, M. Pirinen, C. Spencer, 2014, Human molecular genetics.

Hypomethylation of FAM63B in bipolar disorder patients

A. McQuillin, O. Mors, M. Nyegaard, 2016, Clinical Epigenetics.

Polygenic dissection of the bipolar phenotype

G. Kirov, D. Grozeva, N. Craddock, 2011, British Journal of Psychiatry.

Assessing the burden of rare DNA methylation deviations in schizophrenia

A. Sharp, A. McQuillin, J. Mill, 2023, bioRxiv.

Delineating the psychiatric and behavioral phenotype of recurrent 2q13 deletions and duplications

D. Skuse, A. McQuillin, N. Bass, 2018, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

A rare functional noncoding variant at the GWAS-implicated MIR137/MIR2682 locus might confer risk to schizophrenia and bipolar disorder.

Jianxin Shi, Pablo V Gejman, Jubao Duan, 2014, American journal of human genetics.

Maternally derived microduplications at 15q11-q13: implication of imprinted genes in psychotic illness.

H. Stefánsson, D. Rujescu, S. Cichon, 2011, The American journal of psychiatry.

Analysis of genetic deletions and duplications in the University College London bipolar disorder case control sample

S. Purcell, P. Sklar, H. Gurling, 2011, European Journal of Human Genetics.

Failure to Confirm Allelic Association Between Markers at the CAPON Gene Locus and Schizophrenia in a British Sample

H. Gurling, A. McQuillin, K. Choudhury, 2006, Biological Psychiatry.

Confirmation of prior evidence of genetic susceptibility to alcoholism in a genome-wide association study of comorbid alcoholism and bipolar disorder

S. Purcell, P. Sklar, A. McQuillin, 2011, Psychiatric genetics.

DISC1 association, heterogeneity and interplay in schizophrenia and bipolar disorder

I. Deary, J. Suvisaari, T. Paunio, 2009, Molecular Psychiatry.

Genome-wide Association Study for Alcohol-related Cirrhosis Identifies Risk Loci in MARC1 and HNRNPUL1.

C. Datz, J. Hampe, A. McQuillin, 2020, Gastroenterology.

Genetic Variation in HSD17B13 Reduces the Risk of Developing Cirrhosis and Hepatocellular Carcinoma in Alcohol Misusers

C. Datz, F. Lammert, J. Hampe, 2020, Hepatology.

Homozygosity for rs738409:G in PNPLA3 is associated with increased mortality following an episode of severe alcoholic hepatitis.

A. McQuillin, M. Morgan, S. Atkinson, 2017, Journal of hepatology.

A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis

K. Huse, S. Cichon, M. Rietschel, 2015, Nature Genetics.

Genome-Wide Association Study of Suicide Attempts in Mood Disorder Patients

Michael G. Christel, S. Cichon, M. Rietschel, 2010 .

Adolescent Verbal Memory as a Psychosis Endophenotype: A Genome-Wide Association Study in an Ancestrally Diverse Sample

E. Bramon, A. McQuillin, E. Zartaloudi, 2022, Genes.

A TWO-STAGE GENOME-WIDE ASSOCIATION STUDY CONFIRMS PNPLA 3 AND IDENTIFIES TM 6 SF 2 AND MBOAT 7 AS RISK LOCI FOR ALCOHOL-RELATED CIRRHOSIS

K. Huse, S. Cichon, M. Rietschel, 2017 .

Case–case genome-wide association analysis shows markers differentially associated with schizophrenia and bipolar disorder and implicates calcium channel genes

David Curtis, Khalid Choudhury, Andrew McQuillin, 2011, Psychiatric genetics.

A machine learning case–control classifier for schizophrenia based on DNA methylation in blood

D. Clair, Chathura Gunasekara, C. Coarfa, 2021, Translational Psychiatry.

Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis

B. Franke, O. Andreassen, J. Kelsoe, 2017, Biological Psychiatry.

The Influence of CYP2D6 and CYP2C19 Genetic Variation on Diabetes Mellitus Risk in People Taking Antidepressants and Antipsychotics

Spiros C. Denaxas, E. Bramon, A. McQuillin, 2021, medRxiv.

Association of rare variation in the glutamate receptor gene SLC1A2 with susceptibility to bipolar disorder and schizophrenia

A. McQuillin, S. Sharp, A. Fiorentino, 2014, European Journal of Human Genetics.

A genetic association study of chromosome 11q22-24 in two different samples implicates the FXYD6 gene, encoding phosphohippolin, in susceptibility to schizophrenia.

C. Crombie, G. Fraser, N. Walker, 2007, American journal of human genetics.

Genome scan of Tourette syndrome in a single large pedigree shows some support for linkage to regions of chromosomes 5, 10 and 13

A. McQuillin, D. Curtis, M. Robertson, 2004, Psychiatric genetics.

Genome scan of pedigrees multiply affected with bipolar disorder provides further support for the presence of a susceptibility locus on chromosome 12q23‐q24, and suggests the presence of additional loci on 1p and 1q

H. Pétursson, M. McInnis, H. Gurling, 2003, Psychiatric genetics.

No linkage found between chromosome 11p15.5 markers and manic-depressive illness.

David Curtis, Andrew McQuillin, Jacob Lawrence, 1998 .

A microarray gene expression and genetic association study of the RGS4 gene in schizophrenia

Datta, David Curtis, Andrew McQuillin, 2004 .

Linkage and allelic association studies of the 8p schizophrenia locus.

David Curtis, Andrew McQuillin, Hmd Gurling, 1999 .

A search for the risk allele for bipolar affective disorder on chromosome 12q24.2.

Torben A. Kruse, David Curtis, Andrew McQuillin, 2000 .

Characterization of Age and Polarity at Onset in Bipolar Disorder

Till F. M. Andlauer, S. Cichon, S. Djurovic, 2021, medRxiv.

Evidence of allelic association of bipolar disorder with two genes P2RX7 and AY070435 6 MB apart on 12q24

David Curtis, Andrew McQuillin, Puri, 2005 .

Genome wide parametric genetic linkage analysis of bipolar and related unipolar affective disorders (manic depression) implicates chromosomes 1 and 12.

T. Sigmundsson, H. Pétursson, M. McInnis, 1999 .

NK1 (TACR1) Receptor Gene ‘Knockout’ Mouse Phenotype Predicts Genetic Association with ADHD

S. Stanford, H. Gurling, A. McQuillin, 2010, Journal of psychopharmacology.

Genome‐wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness

Stephan Ripke, Andrew McQuillin, Hugh Gurling, 2016, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

The influence of regression models on genome-wide association studies of alcohol dependence: a comparison of binary and quantitative analyses.

M. Nöthen, A. McQuillin, N. Bass, 2020, Psychiatric genetics.

Genetic variants in ALDH1B1 and alcohol dependence risk in a British and Irish population: A bioinformatic and genetic study

A. McQuillin, M. Morgan, M. Way, 2017, PloS one.

Support of association between BRD1 and both schizophrenia and bipolar affective disorder

S. Purcell, P. Sklar, A. McQuillin, 2010, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Localization of functional regions of the cucumber mosaic virus RNA replicase using monoclonal and polyclonal antibodies.

A. McQuillin, R. Hayes, K. Buck, 1994, The Journal of general virology.

The influence of CYP2D6 and CYP2C19 genetic variation on diabetes mellitus risk in people taking antidepressants and antipsychotics.

Spiros C. Denaxas, E. Bramon, A. McQuillin, 2021, medRxiv.

Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

Kristen K. Dang, D. A. Lewis, C. Spencer, 2019, Nature Genetics.

Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia

D. Rujescu, R. Murray, I. Melle, 2022, JAMA psychiatry.

Variants in PCSK7, PNPLA3 and TM6SF2 are risk factors for the development of cirrhosis in hereditary haemochromatosis

C. Datz, J. Hampe, A. McQuillin, 2021, Alimentary pharmacology & therapeutics.

A genetic risk score and diabetes predict development of alcohol-related cirrhosis in drinkers.

J. Whitfield, M. Pirmohamed, A. McQuillin, 2021, Journal of hepatology.

Heterozygous carriage of the alpha1-antitrypsin Pi*Z variant increases the risk to develop liver cirrhosis

M. Rietschel, C. Datz, C. Trautwein, 2018, Gut.

Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits

A. McQuillin, A. Palmer, M. Nyegaard, 2020, Nature Neuroscience.

Complement genes contribute sex-biased vulnerability in diverse disorders

Christopher W. Whelan, M. Pirinen, C. Spencer, 2020, Nature.

Predictive power of the ADHD GWAS 2019 polygenic risk scores in independent samples of bipolar patients with childhood ADHD.

M. Nöthen, A. McQuillin, N. Bass, 2019, Journal of affective disorders.

Variations in the Promoter Region of the Glutaminase Gene and the Development of Hepatic Encephalopathy in Patients with Cirrhosis

A. McQuillin, M. Morgan, S. Atkinson, 2016 .

PWE-033 Promoter Region Variations in The Glutaminase Gene as A Risk Factor for The Development Hepatic Encephalopathy in Patients with Cirrhosis

A. McQuillin, M. Morgan, S. Atkinson, 2016 .

No evidence that extended tracts of homozygosity are associated with Alzheimer's disease

Michelle K. Lupton, M. Gill, M. Owen, 2011, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Allelic Association, DNA Resequencing and Copy Number Variation at the Metabotropic Glutamate Receptor GRM7 Gene Locus in Bipolar Disorder

H. Gurling, A. McQuillin, D. Curtis, 2014, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Investigating the association between schizophrenia and distance visual acuity: Mendelian randomisation study

A. McQuillin, C. Cooper, G. Lewis, 2023, BJPsych Open.

Corrigendum: TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport

Gail Clement, Jie Huang, Inês Barroso, 2016, Nature Communications.

Effect of the 2004 tsunami on suicide rates in Sri Lanka

A. McQuillin, J. Pimm, A. Rodrigo, 2009 .

Lack of allelic association between markers at the DRD2 and ANKK1 gene loci with the alcohol-dependence syndrome and criminal activity.

D. Ball, H. Gurling, A. McQuillin, 2011, Psychiatric genetics.

Case–control studies show that a non-conservative amino-acid change from a glutamine to arginine in the P2RX7 purinergic receptor protein is associated with both bipolar- and unipolar-affective disorders

A. McQuillin, K. Choudhury, V. Puri, 2009, Molecular Psychiatry.

Prevalence of attention deficit hyperactivity disorder symptoms in patients with schizophrenia

A. McQuillin, G. Giaroli, K. Wolfe, 2018, Acta psychiatrica Scandinavica.

A genomewide association study of response to lithium for prevention of recurrence in bipolar disorder.

S. Purcell, J. Smoller, P. Sklar, 2009, The American journal of psychiatry.

Lack of guidelines and translational knowledge is hindering the implementation of psychiatric genetic counseling and testing within Europe - A multi-professional survey study.

J. Suvisaari, M. Rietschel, A. McQuillin, 2023, European journal of medical genetics.

A Genome-Wide Association Study Identifies PNPLA3 and SLC38A4 as Risk Loci for Alcoholic Hepatitis

A. McQuillin, M. Morgan, S. Atkinson, 2016 .

Prediction of disease comorbidity using explainable artificial intelligence and machine learning techniques: A systematic review

A. McQuillin, J. Thygesen, Jung-Won Choi, 2023, Int. J. Medical Informatics.

Analysis of ANK3 and CACNA1C variants identified in bipolar disorder whole genome sequence data

D. Locke, H. Gurling, A. McQuillin, 2014, Bipolar disorders.

Novel insights into the common heritable liability to addiction: a multivariate genome-wide association study

Z. Kutalik, A. McQuillin, N. Pirastu, 2021, medRxiv.

Principles of Psychiatric Genetics: The genetics of schizophrenia

H. Gurling, A. McQuillin, 2012 .

Optimization of liposome mediated transfection of a neuronal cell line

Andrew D. Miller, A. McQuillin, H. Gurling, 1997, Neuroreport.

Genetic association and sequencing of the insulin‐like growth factor 1 gene in bipolar affective disorder

S. Purcell, P. Sklar, A. McQuillin, 2011, American Journal of Medical Genetics Part B: Neuropsychiatric Genetics.

Sequencing of the ANKYRIN 3 gene (ANK3) encoding ankyrin G in bipolar disorder reveals a non‐conservative amino acid change in a short isoform of ankyrin G

H. Gurling, A. McQuillin, R. Kandaswamy, 2012, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions

Sara B. Linker, Evan Z. Macosko, Thomas G. Gilgenast, 2023, Cell genomics.

Phenotypic heterogeneity in study populations may significantly confound the results of genetic association studies on alcohol dependence

A. McQuillin, A. Thomson, M. Morgan, 2015, Psychiatric genetics.

Positive allelic association of the marker D21S171 with bipolar disorder identifies TRPC7, a calcium channel protein on chromosome 21 at 21q22.3, as being a candidate gene for increasing susceptibility to bipolar and related unipolar affective disorders

A. McQuillin, J. Lawrence, N. Bass, 2002 .

Genetic variation in GABR&bgr;1 and the risk for developing alcohol dependence

A. McQuillin, M. Morgan, Q. Anstee, 2017, Psychiatric genetics.

The UK10K project identifies rare variants in health and disease

Tom R. Gaunt, Thomas M. Keane, Hashem A. Shihab, 2015, Nature.

Rare loss-of-function variants in KMT2F are associated with schizophrenia and developmental disorders

J. Danesh, M. Daly, M. Hurles, 2016, bioRxiv.

Tests of linkage and allelic association between markers in the 1p36 PRKCZ (Protein Kinase C Zeta) gene region and bipolar affective disorder

H. Gurling, A. McQuillin, D. Curtis, 2012, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes.

John P. Rice, Simon C. Potter, Melissa J. Green, 2018, Cell.

Genome-wide association study of over 40,000 bipolar disorder cases provides novel biological insights

John P. Rice, Melissa J. Green, Janice M. Fullerton, 2020, medRxiv.

Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases.

Han Xu, Stephan Ripke, Chongzhi Zang, 2014, American journal of human genetics.

Common variants at ABCA 7 , MS 4 A 6 A / MS 4 A 4 E , EPHA 1 , CD 33 and CD 2 AP are associated with Alzheimer ’ s disease

Nick C Fox, John X. Morris, Thomas W. Mühleisen, 2011 .

Psychosis Endophenotypes: A Gene-Set-Specific Polygenic Risk Score Analysis

D. Rujescu, I. Giegling, E. Bramon, 2023, Schizophrenia bulletin.

Biological Insights From 108 Schizophrenia-Associated Genetic Loci

C. Spencer, K. Davis, P. Visscher, 2014, Nature.

Genome-wide association study of suicide attempts in mood disorder patients.

S. Cichon, M. Rietschel, M. Nöthen, 2010, The American journal of psychiatry.

TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport

Tom R. Gaunt, Thomas M. Keane, Colin A. Johnson, 2015, Nature Communications.

Age at first birth in women is genetically associated with increased risk of schizophrenia

Hoffmann, Hartmann, Roussos, 2017, Scientific Reports.

Schizophrenia genetic variants are not associated with intelligence

A F Terwisscha van Scheltinga, S C Bakker, N E M van Haren, 2013, Psychological Medicine.

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

N. Wray, H. Stefánsson, D. Rujescu, 2019, Nature Genetics.

Rare coding variants in 10 genes confer substantial risk for schizophrenia

S. Gabriel, J. Suvisaari, T. Paunio, 2023 .

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

P. Visscher, J. Sebat, D. Malhotra, 2016, Nature Genetics.

A polygenic risk score analysis of psychosis endophenotypes across brain functional, structural, and cognitive domains

D. Rujescu, E. Bramon, E. Vassos, 2017, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

S. Gabriel, M. Daly, D. Collier, 2008, Nature Genetics.

A threonine to isoleucine missense mutation in the pericentriolar material 1 gene is strongly associated with schizophrenia

C. Crombie, G. Fraser, N. Walker, 2010, Molecular Psychiatry.

The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls.

Melissa J. Green, Janice M. Fullerton, Robert C. Thompson, 2019, Biological psychiatry.

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Genetic, Nick C Fox, Michelle K. Lupton, 2019, Nature Genetics.

Schizophrenia genetic variants are not associated with intelligence

P. Donnelly, P. Visscher, H. Stefánsson, 2013, Psychological Medicine.

GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors.

Philip D. Harvey, I. Giegling, A. Hartmann, 2023, The American journal of psychiatry.

Genome-wide association studies and cross-population meta-analyses investigating short and long sleep duration

Spiros C. Denaxas, Daniel J Buysse, E. Bramon, 2023, Nature communications.

Genome-wide association study of antisocial personality disorder diagnostic criteria provides evidence for shared risk factors across disorders

A. McQuillin, N. Bass, Hang Zhou, 2023, Psychiatric genetics.

Multiple psychiatric polygenic risk scores predict associations between childhood adversity and bipolar disorder.

A. McQuillin, N. Bass, J. Thygesen, 2023, Journal of affective disorders.

A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts.

John P. Rice, Warren W. Kretzschmar, Robert M. Maier, 2021, Biological psychiatry.

Genome-wide Association Study of Alzheimer’s disease with Psychotic Symptoms

Michelle K. Lupton, M. Gill, M. O’Donovan, 2011, Molecular Psychiatry.

Genetic association and sequencing of the insulin‐like growth factor 1 gene in bipolar affective disorder

S. Purcell, P. Sklar, A. McQuillin, 2011, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Genetic Evidence Implicates the Immune System and Cholesterol Metabolism in the Aetiology of Alzheimer's Disease

Thomas W. Mühleisen, Michelle K. Lupton, A. Singleton, 2010, PloS one.

Heterozygous carriage of the alpha1-antitrypsin Pi*Z variant increases the risk to develop liver cirrhosis

M. Rietschel, C. Datz, C. Trautwein, 2018, Gut.

Journal Pre-proof for Identifies

C. Datz, A. McQuillin, S. Buch, 2020 .

How data science can advance mental health research

Zina M. Ibrahim, R. Dobson, A. McIntosh, 2018, Nature Human Behaviour.

Evidence for Genetic Overlap Between Schizophrenia and Age at First Birth in Women.

P. Visscher, E. Bramon, S. Djurovic, 2016, JAMA psychiatry.

No consistent evidence for association between mtDNA variants and Alzheimer disease

Nick C Fox, John X. Morris, Michelle K. Lupton, 2012, Neurology.