J. Knowles

S. E. Stewart, R. Delorme, E. Cook, 2013, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Significant linkage to compulsive hoarding on chromosome 14 in families with obsessive-compulsive disorder: results from the OCD Collaborative Genetics Study.

V. Willour, S. Rauch, D. Murphy, 2007, The American journal of psychiatry.

A CTGF-YAP Regulatory Pathway Is Essential for Angiogenesis and Barriergenesis in the Retina

J. Knowles, Sangmi Lee, B. Chaqour, 2020, bioRxiv.

Parent-of-origin effect in panic disorder.

S. Hodge, M. Weissman, A. Fyer, 1999, American journal of medical genetics.

Self-reported health and smoking status, and body mass index: a case-control comparison based on GEN SCRIP (GENetics of SChizophRenia In Pakistan) data

Muntazir Mehdi, C. Pato, M. Pato, 2021, BMJ Open.

Gender differences in genetic linkage and association on 11p15 in obsessive–compulsive disorder families

S. Rauch, D. Murphy, B. Greenberg, 2009, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Non-coding RNAs derived from an alternatively spliced REST transcript (REST-003) regulate breast cancer invasiveness

J. Knowles, A. Weitz, R. Chow, 2015, Scientific Reports.

Regulation of Synaptic nlg-1/Neuroligin Abundance by the skn-1/Nrf Stress Response Pathway Protects against Oxidative Stress

J. Knowles, D. Sieburth, Trisha A. Staab, 2014, PLoS genetics.

Genetics of recurrent early-onset major depression (GenRED): significant linkage on chromosome 15q25-q26 after fine mapping with single nucleotide polymorphism markers.

Diana, J. Potash, M. Gladis, 2007, The American journal of psychiatry.

BMPR2 mutations in pulmonary arterial hypertension with congenital heart disease

J. Knowles, R. Barst, J. McElroy, 2004, European Respiratory Journal.

Pulmonary arterial hypertension: future directions: report of a National Heart, Lung and Blood Institute/Office of Rare Diseases workshop.

J. Knowles, D. Gail, S. Archer, 2004, Circulation.

Correction: Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

P. O’Reilly, A. Danese, P. Visscher, 2020, Molecular Psychiatry.

Familial pulmonary arterial hypertension, leucopenia, and atrial septal defect: a probable new familial syndrome with multisystem involvement

J. Knowles, R. Barst, A. Dursun, 2009, Clinical dysmorphology.

Isolation, characterization, and expression of the gene encoding the late histone subtype H1-gamma of the sea urchin Strongylocentrotus purpuratus

J. Knowles, Z. Lai, G. Childs, 1987, Molecular and cellular biology.

Isolation, Characterization, and Expression of the Gene Encoding the Late Histone Subtype Hi-Gamma of the Sea Urchin Strongylocentrotus purpuratus

J. Knowles, Z. Lai, G. Childs, 2022 .

Refinement of the spinal muscular atrophy locus to the interval between D5S435 and MAP1B.

T. Gilliam, J. Knowles, G. Penchaszadeh, 1993, Genomics.

Multivariate analysis of anxiety disorders yields further evidence of linkage to chromosomes 4q21 and 7p in panic disorder families

M. Weissman, A. Fyer, M. Weissman, 2012, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Genetic aspects of pulmonary arterial hypertension.

J. Knowles, J. Morse, Z. Deng, 2001, Annals medicus.

Cell type catalog of middle turbinate epithelium

J. Knowles, O. Evgrafov, Fasil Mathews, 2022, bioRxiv.

Self-reported executive function and hoarding in adults with obsessive-compulsive disorder.

D. Murphy, B. Greenberg, A. Fyer, 2018, Comprehensive psychiatry.

Endogenous Cell Type-Specific DISC1 Interactomes Reveal Protein Networks Associated to Neurodevelopmental Disorders

J. Knowles, B. Wilkinson, M. Coba, 2019 .

Comprehensive family‐based association study of the glutamate transporter gene SLC1A1 in obsessive‐compulsive disorder

S. Rauch, B. Greenberg, A. Fyer, 2011, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Bone morphogenetic protein receptor 2 mutations in adults and children with idiopathic pulmonary arterial hypertension: association with thyroid disease.

J. Knowles, K. Chada, R. Barst, 2005, Chest.

Dorsal Amygdala Neurotrophin-3 Decreases Anxious Temperament in Primates

Ethan K. Brodsky, Andrew L. Alexander, Andrew S. Fox, 2019, Biological Psychiatry.

Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene.

S. Hodge, J. Knowles, S. Slager, 2000, American journal of human genetics.

Is obsessive–compulsive disorder an anxiety disorder, and what, if any, are spectrum conditions? A family study perspective

S. Rauch, D. Murphy, B. Greenberg, 2011, Psychological Medicine.

Evidence for potential relationship between SLC1A1 and a putative genetic linkage region on chromosome 14q to obsessive‐compulsive disorder with compulsive hoarding

S. Rauch, D. Murphy, B. Greenberg, 2008, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Familiality of Factor Analysis-Derived YBOCS Dimensions in OCD-Affected Sibling Pairs from the OCD Collaborative Genetics Study

Benjamin D. Greenberg, Ying Wang, Gregor Hasler, 2007, Biological Psychiatry.

Clinically effective OCD treatment prevents 5-HT1B receptor-induced repetitive behavior and striatal activation

J. Knowles, William R. Katzka, S. Dulawa, 2015, Psychopharmacology.

De novo variants in GREB1L are associated with non-syndromic inner ear malformations and deafness

D. Raible, J. Knowles, M. Huentelman, 2018, Human Genetics.

Lack of genetic linkage or association between a functional serotonin transporter polymorphism and panic disorder.

S. Hodge, M. Weissman, D. Klein, 1999, Psychiatric genetics.

Effect of RNA integrity on uniquely mapped reads in RNA-Seq

J. Knowles, O. Evgrafov, T. Souaiaia, 2014, BMC Research Notes.

Study protocol of DIVERGE, the first genetic epidemiological study of major depressive disorder in Pakistan

J. Knowles, Farooq Naeem, M. Ayub, 2022, Psychiatric genetics.

D8/17 in obsessive-compulsive disorder and trichotillomania.

Dan J Stein, J. Knowles, S. Seedat, 1999, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.

Comparison of the late H1 histone genes of the sea urchins Lytechinus pictus and Strongelocentrotus purpuratus.

J. Knowles, G. Childs, 1986, Nucleic acids research.

The autism-associated gene chromodomain helicase DNA-binding protein 8 (CHD8) regulates noncoding RNAs and autism-related genes

J. Knowles, B. Wilkinson, O. Evgrafov, 2015, Translational Psychiatry.

Obsessive–compulsive disorder: subclassification based on co-morbidity

S. Rauch, D. Murphy, B. Greenberg, 2008, Psychological Medicine.

Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders

Michael J. Purcaro, Emily E. Burke, Annie W Shieh, 2021, Nature Communications.

Age at first birth in women is genetically associated with increased risk of schizophrenia

Hoffmann, Hartmann, Roussos, 2017, Scientific Reports.

Early- versus late-onset obsessive–compulsive disorder: investigating genetic and clinical correlates

D. Stein, J. Knowles, J. Moolman-Smook, 2004, Psychiatry Research.

BMPR2 germline mutations in pulmonary hypertension associated with fenfluramine derivatives

S. Hodge, M. Humbert, J. Knowles, 2002, European Respiratory Journal.

Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology

Dan J Stein, Melissa J. Green, Janice M. Fullerton, 2021, Nature Genetics.

Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium

John P. Rice, Warren W. Kretzschmar, Robert M. Maier, 2017, Biological Psychiatry.

Novel loci for major depression identified by genome-wide association study of STAR*D and meta-analysis of three studies

J. Knowles, D. Jancic, W. Coryell, 2009, Molecular Psychiatry.

Tubby-like protein 1 homozygous splice-site mutation causes early-onset severe retinal degeneration.

J. Ott, T. Aleman, A. Cideciyan, 1999, Investigative ophthalmology & visual science.

Identification of common genetic risk variants for autism spectrum disorder

John P. Rice, Warren W. Kretzschmar, Robert M. Maier, 2019, Nature Genetics.

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

Laura J. Scott, Naomi R. Wray, Margaret A. Pericak-Vance, 2015, Nature Neuroscience.

Genome-wide association study identifies new locus associated with OCD

Dan J Stein, Ben D. Greenberg, M. S. Artigas, 2021, medRxiv.

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

Wei Cheng, Jianxin Shi, Elvira Bramon, 2016, Nature Genetics.

Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study.

Dan J Stein, F. A. Schroeder, S. E. Stewart, 2014, Journal of the American Academy of Child and Adolescent Psychiatry.

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

Michael F. Green, Max W. Y. Lam, Catherine A. Sugar, 2022, Nature.

Gene Expression in Patient-Derived Neural Progenitors Implicates WNT5A Signaling in the Etiology of Schizophrenia

C. Pato, M. Pato, H. Medeiros, 2019, Biological Psychiatry.

The genetics of the mood disorder spectrum: genome-wide association analyses of over 185,000 cases and 439,000 controls

Melissa J. Green, Robert C. Thompson, Pamela B. Mahon, 2018, bioRxiv.

Genome-wide association study identifies 30 Loci Associated with Bipolar Disorder

Melissa J. Green, Robert C. Thompson, Pamela B. Mahon, 2017, bioRxiv.

Autism spectrum disorder trios from consanguineous populations are enriched for rare biallelic variants, identifying 32 new candidate genes

J. Vincent, J. Knowles, L. French, 2021, medRxiv.

Association study of 83 candidate genes for bipolar disorder in chromosome 6q selected using an evidence‐based prioritization algorithm

F. McMahon, Zhongming Zhao, C. Pato, 2013, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Ultra-rare genetic variation in the epilepsies: a whole-exome sequencing study of 17,606 individuals

Michael R. Johnson, S. Gabriel, M. Daly, 2019, bioRxiv.

Rare coding variants in ten genes confer substantial risk for schizophrenia

S. Gabriel, M. Daly, H. Kang, 2022, Nature.

Gene Expression in Patient-Derived Neural Progenitors Implicates WNT5A Signaling in the Etiology of Schizophrenia

C. Pato, M. Pato, H. Medeiros, 2017, Biological Psychiatry.

Noncoding RNA in the transcriptional landscape of human neural progenitor cell differentiation

Patrick M. Hecht, J. Knowles, I. Ballesteros-Yáñez, 2015, Front. Neurosci..

A polygenic resilience score moderates the genetic risk for schizophrenia

M. Pirinen, P. Donnelly, C. Spencer, 2019, Molecular Psychiatry.

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders

Fengzhu Sun, Hui Yang, Giulio Genovese, 2017, Nature Neuroscience.

Exome sequencing in obsessive–compulsive disorder reveals a burden of rare damaging coding variants

B. Greenberg, A. Fyer, Anthony W. Zoghbi, 2021, Nature Neuroscience.

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

Benjamin A. Logsdon, Hae Kyung Im, Solveig K Sieberts, 2019, Nature Genetics.

Interrogating the Genetic Determinants of Tourette's Syndrome and Other Tic Disorders Through Genome-Wide Association Studies.

H. Stefánsson, N. Freimer, R. Ophoff, 2019, The American journal of psychiatry.

Concordance of genetic variation that increases risk for Tourette Syndrome and that influences its underlying neurocircuitry

Neda Jahanshad, Emile R Chimusa, Shareefa Dalvie, 2018, bioRxiv.

Rare Copy Number Variants in NRXN1 and CNTN6 Increase Risk for Tourette Syndrome

Douglas W. Woods, Jae Hoon Sul, Michael S. Okun, 2016, Neuron.

Using 3D epigenomic maps of primary olfactory neuronal cells from living individuals to understand gene regulation

B. Berman, P. Farnham, J. Knowles, 2018, Science Advances.

A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts

John P. Rice, Robert M. Maier, C. Spencer, 2020, Biological Psychiatry.

Investigation of polymorphisms in the CREM gene in panic disorder

S. Hodge, M. Weissman, D. Klein, 2004, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Evidence for a susceptibility locus for panic disorder near the catechol-O-methyltransferase gene on chromosome 22

Steven P. Hamilton, Susan L. Slager, Myrna M. Weissman, 2000, Biological Psychiatry.

EphA7 regulates spiral ganglion innervation of cochlear hair cells

Huizhong W Tao, Li I. Zhang, James A Knowles, 2016, Developmental neurobiology.

Investigating the role of dopaminergic and serotonergic candidate genes in obsessive-compulsive disorder

D. Stein, J. Knowles, J. Moolman-Smook, 2003, European Neuropsychopharmacology.

Polygenic selection underlies evolution of human brain structure and behavioral traits

P. Thompson, D. Stein, B. Stranger, 2017, bioRxiv.

Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

John P. Rice, Warren W. Kretzschmar, Robert M. Maier, 2020, Biological Psychiatry.

Corrigendum to “Gender in obsessive–compulsive disorder: clinical and genetic findings” [Eur. Neuropsychopharmacol. 14/2 (2004) 105–113]

D. Stein, J. Knowles, J. Moolman-Smook, 2004, European Neuropsychopharmacology.

Gender in obsessive–compulsive disorder: clinical and genetic findings

James A. Knowles, Dan J. Stein, Christine Lochner, 2004, European Neuropsychopharmacology.

Single-neuron RNA-Seq: technical feasibility and reproducibility

Shenfeng Qiu, Pat Levitt, Gary P. Schroth, 2012, Front. Gene..

Single-neuron RNA-Seq: technical feasibility and

S. Luo, G. Schroth, J. Knowles, 2012 .

Deconvolution of Transcriptional Networks Identified TCF4 as a Master Regulator in Schizophrenia

J. Knowles, J. Duan, O. Evgrafov, 2017, bioRxiv.

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

D. Rujescu, S. Cichon, I. Giegling, 2021, Biological Psychiatry.

Complement genes contribute sex-biased vulnerability in diverse illnesses

Simon C. Potter, Christopher W. Whelan, M. Pirinen, 2020, Nature.

Polygenic risk score-based phenome-wide association study identifies novel associations for Tourette syndrome

M. Daly, H. Stefánsson, R. Ophoff, 2022, Translational Psychiatry.

Contribution of Rare Copy Number Variants to Bipolar Disorder Risk Is Limited to Schizoaffective Cases

N. Craddock, S. Mccarroll, H. Nicolini, 2018, Biological Psychiatry.

Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder

N. Craddock, S. Mccarroll, H. Nicolini, 2017, Translational Psychiatry.

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

John P. Rice, A. Danese, P. Visscher, 2019, Molecular Psychiatry.

Genome-wide Association Study of Pediatric Obsessive-Compulsive Traits: Shared Genetic Risk between Traits and Disorder

Dan J Stein, Ben D. Greenberg, R. Delorme, 2019, bioRxiv.

Concordance of genetic variation that increases risk for anxiety disorders and posttraumatic stress disorders and that influences their underlying neurocircuitry.

Israel Liberzon, Neda Jahanshad, Shareefa Dalvie, 2019, Journal of affective disorders.

Significant concordance of genetic variation that increases both the risk for obsessive-compulsive disorder and the volumes of the nucleus accumbens and putamen.

Neda Jahanshad, Shareefa Dalvie, Sarah E Medland, 2018, The British journal of psychiatry : the journal of mental science.

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture ofmajor depressive disorder

Li, Katharina, Warren W. Kretzschmar, 2018 .

GENOME-WIDE ASSOCIATION ANALYSES IDENTIFY 44 RISK VARIANTS AND REFINE THE GENETIC ARCHITECTURE OF MAJOR DEPRESSIVE DISORDER

John P. Rice, Warren W. Kretzschmar, Robert M. Maier, 2019, European Neuropsychopharmacology.

Genetic correlation between amyotrophic lateral sclerosis and schizophrenia

Denis C. Bauer, Annelot M. Dekker, Ashley R. Jones, 2017, Nature Communications.

Genetics of recurrent early-onset major depression (GenRED): final genome scan report.

J. Steele, J. Potash, M. Gladis, 2007, The American journal of psychiatry.

Bone morphogenetic protein receptor type II C-terminus interacts with c-Src: implication for a role in pulmonary arterial hypertension.

J. Knowles, J. Morse, W. Wong, 2005, American journal of respiratory cell and molecular biology.

Sea urchin (Lytechinus pictus) late-stage histone H3 and H4 genes: Characterization and mapping of a clustered but nontandemly linked multigene family

J. Knowles, C. Holt, G. Childs, 1982, Cell.

Identification of a novel member of the TGF-beta superfamily highly expressed in human placenta.

M. Soares, M. Bonaldo, J. Knowles, 1997, Gene.

Genes Implicated in Rare Congenital Inner Ear and Cochleovestibular Nerve Malformations

S. Leal, J. Knowles, M. Huentelman, 2020, Ear and hearing.

Olfactory neuroepithelium-derived neural progenitor cells as a model system for investigating the molecular mechanisms of neuropsychiatric disorders

J. Knowles, D. Malaspina, O. Evgrafov, 2011, Psychiatric genetics.

Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

Janice M. Fullerton, Warren W. Kretzschmar, Robert M. Maier, 2020, Molecular Psychiatry.

Childhood Trauma and Psychotic Symptomatology in Ethnic Minorities With Schizophrenia

C. Pato, M. Pato, A. Fanous, 2021, Schizophrenia Bulletin Open.

No evidence for significant linkage between bipolar affective disorder and chromosome 18 pericentromeric markers in a large series of multiplex extended pedigrees.

J. R. Alexander, J. Ott, T. Gilliam, 1998, American journal of human genetics.

Polygenic risk score and heritability estimates reveals a genetic relationship between ASD and OCD

B. Greenberg, A. Fyer, J. Knowles, 2017, European Neuropsychopharmacology.

Genetic overlap of schizophrenia and bipolar disorder in a high‐density linkage survey in the Portuguese Island population

Zhongming Zhao, F. Middleton, C. Pato, 2012, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Linkage Disequilibrium Mapping of a Chromosome 15q25-26 Major Depression Linkage Region and Sequencing of NTRK3

J. Potash, M. Weissman, P. Holmans, 2008, Biological Psychiatry.

B. Greenberg, J. Knowles, Y. Shugart, 2019, Journal of child and adolescent psychopharmacology.

Btbd3 expression regulates compulsive-like and exploratory behaviors in mice

J. Knowles, C. Portugal-Nunes, S. Dulawa, 2019, Translational Psychiatry.

Examination of the Shared Genetic Basis of Anorexia Nervosa and Obsessive-Compulsive Disorder

G. Breen, M. Kas, J. Knowles, 2017, bioRxiv.

Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD.

S. E. Stewart, C. Sabatti, N. Freimer, 2015, The American journal of psychiatry.

The genomic psychiatry cohort: Partners in discovery

S. Mccarroll, H. Nicolini, S. Purcell, 2013, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Significant linkage to compulsive hoarding on chromosome 14 in families with obsessive-compulsive disorder: results from the OCD Collaborative Genetics Study.

V. Willour, S. Rauch, D. Murphy, 2007, The American journal of psychiatry.

Genome Wide Association Study (GWAS) between Attention Deficit Hyperactivity Disorder (ADHD) and Obsessive Compulsive Disorder (OCD)

D. Murphy, B. Greenberg, A. Fyer, 2017, Front. Mol. Neurosci..

Next Generation Sequence Analysis and Computational Genomics Using Graphical Pipeline Workflows

Arthur W. Toga, Carl Kesselman, Ivo D. Dinov, 2012, Genes.

When tractography meets tracer injections: a systematic study of trends and variation sources of diffusion-based connectivity

Maite Christi Francois, Hong-wei Dong, A. Toga, 2018, Brain Structure and Function.

A de novo SIX1 variant in a patient with a rare nonsyndromic cochleovestibular nerve abnormality, cochlear hypoplasia, and bilateral sensorineural hearing loss

S. Leal, J. Knowles, M. Huentelman, 2019, Molecular genetics & genomic medicine.

Compound heterozygous mutations in MASP1 in a deaf child with absent cochlear nerves

J. Knowles, M. Huentelman, J. Go, 2017, Neurology: Genetics.

Assessing characteristics of RNA amplification methods for single cell RNA sequencing

Jian-Bing Fan, Hannah Dueck, Junhyong Kim, 2016, BMC Genomics.

Assessing the measurement transfer function of single-cell RNA sequencing

Jian-Bing Fan, Hannah Dueck, Wei Wang, 2016, bioRxiv.

Genetic effects influencing risk for major depressive disorder in China and Europe

John P. Rice, N. Wray, S. Cichon, 2017, Translational Psychiatry.

Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

John P. Rice, Warren W. Kretzschmar, Robert M. Maier, 2019, Biological psychiatry. Cognitive neuroscience and neuroimaging.

A linkage search for joint panic disorder/bipolar genes

S. Hodge, A. Fyer, M. Weissman, 2009, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Transcriptional Gene Silencing of the Autism-Associated Long Noncoding RNA MSNP1AS in Human Neural Progenitor Cells

Patrick M. Hecht, K. Morris, J. Knowles, 2016, Developmental Neuroscience.

Apparent mtDNA heteroplasmy in Alzheimer's disease patients and in normals due to PCR amplification of nucleus-embedded mtDNA pseudogenes.

S. Dimauro, E. Schon, R. Mayeux, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Genetics of primary pulmonary hypertension

J. Knowles, J. Morse, 2001 .

Comorbidity of severe psychotic disorders with measures of substance use.

Sarah M. Hartz, Patricia A. Cavazos-Rehg, L. Bierut, 2014, JAMA psychiatry.

Robust RNA-Seq of aRNA-amplified single cell material collected by patch clamp

J. Knowles, R. Chow, O. Evgrafov, 2020, Scientific Reports.

Homeobox genes in obsessive‐compulsive disorder

S. Rauch, B. Greenberg, A. Fyer, 2012, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Genetic effects influencing risk for major depressive disorder in China and Europe

John P. Rice, Till F. M. Andlauer, N. Wray, 2017, Translational Psychiatry.

Fine genetic mapping of a gene for autosomal recessive retinitis pigmentosa on chromosome 6p21.

T. Matise, J. Ott, S. Jacobson, 1995, American journal of human genetics.

Genetics of recurrent early‐onset depression (GenRED): Design and preliminary clinical characteristics of a repository sample for genetic linkage studies

P. Holmans, M. McInnis, M. Weissman, 2003, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders

N. Wray, H. Stefánsson, S. Cichon, 2015, Neuron.

Association between a catechol-o-methyltransferase polymorphism and obsessive-compulsive disorder in the Afrikaner population.

D. Stein, R. Emsley, J. Knowles, 2001, Journal of affective disorders.

Transcriptome data of temporal and cingulate cortex in the Rett syndrome brain

James W. MacDonald, J. Knowles, O. Evgrafov, 2020, Scientific Data.

Transcriptome data of temporal and cingulate cortex in the Rett syndrome brain

James W. MacDonald, J. Knowles, P. Levitt, 2020, Scientific Data.

Evaluation of biological and technical variations in low-input RNA-Seq and single-cell RNA-Seq

Kai Wang, Fan Gao, Ming-Yi Lin, 2018, Int. J. Comput. Biol. Drug Des..

The Conserved SKN-1/Nrf2 Stress Response Pathway Regulates Synaptic Function in Caenorhabditis elegans

J. Knowles, O. Evgrafov, T. Griffen, 2013, PLoS genetics.

Bipolar disorder and chromosome 18p11: uncertainties redux.

J. Knowles, M. Baron, 2000, Psychiatric genetics.

Perils of gene mapping with microsatellite markers.

V. Vieland, T. Gilliam, J. Knowles, 1992, American journal of human genetics.

Meta-analyses of genome-wide linkage scans of anxiety-related phenotypes

N. Wray, Zhongming Zhao, P. Sham, 2012, European Journal of Human Genetics.

Evidence for Genetic Linkage Between a Polymorphism in the Adenosine 2A Receptor and Panic Disorder

Susan E Hodge, Myrna M Weissman, James A Knowles, 2004, Neuropsychopharmacology.

Potential panic disorder syndrome: clinical and genetic linkage evidence.

S. Hodge, M. Weissman, R. Hen, 2000, American journal of medical genetics.

TULP1 mutation in two extended Dominican kindreds with autosomal recessive Retinitis pigmentosa

J. Ott, S. Jacobson, T. Gilliam, 1998, Nature Genetics.

Whole genome association analysis of treatment response in obsessive-compulsive disorder

D. Murphy, B. Greenberg, A. Fyer, 2015, Molecular Psychiatry.

Characterization of Age and Polarity at Onset in Bipolar Disorder

Janice M. Fullerton, Till F. M. Andlauer, S. Cichon, 2021, medRxiv.

A comprehensive linkage analysis of chromosome 21q22 supports prior evidence for a putative bipolar affective disorder locus.

J. Terwilliger, T. Gilliam, J. Endicott, 1999, American journal of human genetics.

Investigation of dopamine receptor (DRD4) and dopamine transporter (DAT) polymorphisms for genetic linkage or association to panic disorder.

S. Hodge, M. Weissman, D. Klein, 2000, American journal of medical genetics.

An investigation of doubt in obsessive-compulsive disorder.

S. E. Stewart, D. Murphy, B. Greenberg, 2017, Comprehensive psychiatry.

Hoarding in Children and Adolescents with Obsessive-Compulsive Disorder.

S. E. Stewart, D. Murphy, B. Greenberg, 2014, Journal of obsessive-compulsive and related disorders.

Further development of YBOCS dimensions in the OCD Collaborative Genetics Study: Symptoms vs. categories

V. Willour, S. Rauch, D. Murphy, 2008, Psychiatry Research.

Chromosome 18p11 and linkage to bipolar disorder revisited.

J. Knowles, M. Baron, 1999, Psychiatric genetics.

Association of SLC6A4 variants with obsessive-compulsive disorder in a large multi-center US family study

S. Rauch, D. Murphy, B. Greenberg, 2009, Molecular Psychiatry.

The human GCAP1 and GCAP2 genes are arranged in a tail-to-tail array on the short arm of chromosome 6 (p21.1).

J. D. Bronson, J. Knowles, K. Palczewski, 1997, Genomics.

Evolutionary conservation and mutational spectrum of BMPR2 gene.

J. Knowles, J. Morse, W. Wong, 2006, Gene.

Genetic aspect of pulmonary arterial hypertension

J. Knowles, J. Morse, Z. Deng, 2001 .

Trichotillomania comorbidity in a sample enriched for familial obsessive-compulsive disorder.

S. Rauch, B. Greenberg, J. Knowles, 2019, Comprehensive psychiatry.

Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

Kristen K. Dang, D. A. Lewis, C. Spencer, 2019, Nature Genetics.

Genome-wide Burden of Rare Short Deletions Is Enriched in Major Depressive Disorder in Four Cohorts

John P. Rice, M. Rietschel, J. Potash, 2019, Biological Psychiatry.

Impact of the Autism-Associated Long Noncoding RNA MSNP1AS on Neuronal Architecture and Gene Expression in Human Neural Progenitor Cells

J. Knowles, B. Wilkinson, O. Evgrafov, 2016, Genes.

Dlgap1 knockout mice exhibit alterations of the postsynaptic density and selective reductions in sociability

S. Grant, J. Knowles, M. Coba, 2018, Scientific Reports.

Homozygosity and physical mapping of the autosomal recessive retinitis pigmentosa locus (RP14) on chromosome 6p21.3.

J. Ott, S. Jacobson, T. Gilliam, 1998, Genomics.

Identification of a locus, distinct from RDS-peripherin, for autosomal recessive retinitis pigmentosa on chromosome 6p.

J. Ott, S. Jacobson, T. Gilliam, 1994, Human molecular genetics.

Prognostic factors for survival in human immunodeficiency virus-associated pulmonary arterial hypertension.

M. Humbert, J. Knowles, R. Barst, 2003, American journal of respiratory and critical care medicine.

Is Persistent Motor or Vocal Tic Disorder a Milder Form of Tourette Syndrome?

B. Greenberg, J. Knowles, J. McCracken, 2021, Movement disorders : official journal of the Movement Disorder Society.

Fine mapping of 10q and 18q for familial Alzheimer's disease in Caribbean Hispanics

J. H. Lee, B. Tycko, R. Mayeux, 2004, Molecular Psychiatry.

Chromosome-12 mapping of late-onset Alzheimer disease among Caribbean Hispanics.

J. H. Lee, B. Tycko, R. Mayeux, 2002, American journal of human genetics.

The OCD collaborative genetics study: Methods and sample description

V. Willour, S. Rauch, B. Greenberg, 2006, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Obsessive-compulsive disorder and the promoter region polymorphism (5-HTTLPR) in the serotonin transporter gene (SLC6A4): a negative association study in the Afrikaner population.

D. Stein, R. Emsley, J. Knowles, 2000, The international journal of neuropsychopharmacology.

Genetic risk factors for portopulmonary hypertension in patients with advanced liver disease.

H. Tighiouart, J. Knowles, D. Rabinowitz, 2009, American journal of respiratory and critical care medicine.

Neuropeptide Secreted from a Pacemaker Activates Neurons to Control a Rhythmic Behavior

J. Knowles, Kelly M. Girskis, L. Schoofs, 2013, Current Biology.

Complement genes contribute sex-biased vulnerability in diverse disorders

Christopher W. Whelan, M. Pirinen, C. Spencer, 2020, Nature.

Association and linkage analysis of candidate genes GRP, GRPR, CRHR1, and TACR1 in panic disorder

M. Weissman, A. Fyer, J. Knowles, 2009, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Parental bonding and hoarding in obsessive-compulsive disorder.

S. E. Stewart, D. Murphy, B. Greenberg, 2017, Comprehensive psychiatry.

Prevalence and correlates of lifetime suicide attempt in obsessive-compulsive disorder with major depression.

S. E. Stewart, B. Greenberg, A. Fyer, 2023, Journal of psychiatric research.

Recurrent Rare Copy Number Variants Increase Risk for Esotropia

C. Pato, M. Pato, J. Knowles, 2020, Investigative ophthalmology & visual science.

High-resolution mapping and transcript identification at the progressive epilepsy with mental retardation locus on chromosome 8p.

T. Gilliam, P. D. de Jong, M. Soares, 1997, Genome research.

Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease.

H. Tighiouart, J. Knowles, V. Shah, 2010, Gastroenterology.

Clinical implications of determining BMPR2 mutation status in a large cohort of children and adults with pulmonary arterial hypertension.

J. Knowles, S. Rich, K. Chada, 2008, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

Fine mapping of PPH1, a gene for familial primary pulmonary hypertension, to a 3-cM region on chromosome 2q33.

S. Hodge, J. Knowles, R. Barst, 2000, American journal of respiratory and critical care medicine.

Sapap3 and pathological grooming in humans: Results from the OCD collaborative genetics study

V. Willour, S. Rauch, D. Murphy, 2009, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Serotonin transporter polymorphisms in familial and idiopathic pulmonary arterial hypertension.

M. Humbert, J. Knowles, R. Barst, 2006, American journal of respiratory and critical care medicine.

University of Groningen Examination of the shared genetic basis of anorexia nervosa and obsessive-compulsive disorder Eating Disorders Working Group of the Psychiatric Genomics Consortium

G. Breen, M. Kas, J. Knowles, 2018 .

Deconvolution of transcriptional networks identifies TCF4 as a master regulator in schizophrenia

J. Knowles, J. Duan, O. Evgrafov, 2019, Science Advances.

Robust RNA-Seq of aRNA-amplified single cell material collected by patch clamp

J. Knowles, R. Chow, O. Evgrafov, 2020, Scientific Reports.

General personality dimensions, impairment and treatment response in obsessive-compulsive disorder.

S. E. Stewart, D. Murphy, B. Greenberg, 2019, Personality and mental health.

ADHD and executive functioning deficits in OCD youths who hoard.

S. E. Stewart, D. Murphy, B. Greenberg, 2016, Journal of psychiatric research.

Hoarding in obsessive-compulsive disorder: results from the OCD Collaborative Genetics Study.

V. Willour, S. Rauch, D. Murphy, 2007, Behaviour research and therapy.

Evidence for Linkage and Association of GABRB3 and GABRA5 to Panic Disorder

M. Weissman, A. Fyer, J. Knowles, 2014, Neuropsychopharmacology.

Sex-specific clinical correlates of hoarding in obsessive-compulsive disorder.

S. Rauch, D. Murphy, B. Greenberg, 2008, Behaviour research and therapy.

Dependent personality, separation anxiety disorder and other anxiety disorders in OCD.

S. Rauch, D. Murphy, B. Greenberg, 2016, Personality and mental health.

Greater history of traumatic event exposure and PTSD associated with comorbid body dysmorphic disorder in a large OCD cohort

K. Phillips, C. Pato, M. Pato, 2020, Psychiatry Research.

RseqFlow: workflows for RNA-Seq data analysis

Ying Wang, Ting Chen, Ewa Deelman, 2011, Bioinform..

Enabling Data and Compute Intensive Workflows in Bioinformatics

Ying Wang, Ting Chen, Ewa Deelman, 2011, Euro-Par Workshops.

Hoarding in obsessive-compulsive disorder: clinical and genetic correlates.

D. Stein, J. Knowles, S. Seedat, 2005, The Journal of clinical psychiatry.

Investigating the role of p11 (S100A10) sequence variation in susceptibility to major depression

J. Potash, P. Holmans, D. Cutler, 2007, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Separation anxiety disorder in OCD

S. Rauch, D. Murphy, B. Greenberg, 2011, Depression and anxiety.

Serotonin transporter polymorphisms in patients with portopulmonary hypertension.

J. Knowles, J. Trotter, R. Benza, 2009, Chest.

Endogenous Cell Type–Specific Disrupted in Schizophrenia 1 Interactomes Reveal Protein Networks Associated With Neurodevelopmental Disorders

J. Knowles, B. Wilkinson, M. Coba, 2019, Biological Psychiatry.

A family‐based association study of the glutamate transporter gene SLC1A1 in obsessive–compulsive disorder in 378 families

S. Rauch, B. Greenberg, A. Fyer, 2009, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Demographic and clinical characteristics associated with treatment status in family members with obsessive‐compulsive disorder

V. Willour, S. Rauch, B. Greenberg, 2008, Depression and anxiety.

Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions

Sara B. Linker, Evan Z. Macosko, Thomas G. Gilgenast, 2023, Cell genomics.

Cultured Mesenchymal Cells from Nasal Turbinate as a Cellular Model of the Neurodevelopmental Component of Schizophrenia Etiology

M. Pato, J. Knowles, O. Evgrafov, 2023, bioRxiv.

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes.

John P. Rice, Simon C. Potter, Melissa J. Green, 2018, Cell.

Genome-wide association study of over 40,000 bipolar disorder cases provides novel biological insights

John P. Rice, Melissa J. Green, Janice M. Fullerton, 2020, medRxiv.

Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases.

Han Xu, Stephan Ripke, Chongzhi Zang, 2014, American journal of human genetics.

Genetic homogeneity between acute and chronic forms of spinal muscular atrophy

T. Lehner, J. Ott, T. Gilliam, 1990, Nature.

Biological Insights From 108 Schizophrenia-Associated Genetic Loci

C. Spencer, K. Davis, P. Visscher, 2014, Nature.

Corrigendum to “Gender in obsessive-compulsive disorder: clinical and genetic findings” [Eur. Neuropsychopharmacol. 14 (2) (2004) 105–113]

D. Stein, J. Knowles, J. Moolman-Smook, 2004, European Neuropsychopharmacology.

Clinical correlates and genetic linkage of social and communication difficulties in families with obsessive–compulsive disorder: Results from the OCD Collaborative Genetics Study

S. Rauch, D. Murphy, B. Greenberg, 2014, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

OBSESSIVE–COMPULSIVE PERSONALITY DISORDER: EVIDENCE FOR TWO DIMENSIONS

S. Rauch, J. Knowles, Benjamin D. Greenberg, 2016, Depression and anxiety.

Genetic variants specific to aging-related verbal memory: Insights from GWASs in a population-based cohort

J. Knowles, C. Prescott, N. Pendleton, 2017, PloS one.

Reverse Engineering of Trascriptional Networks Uncovers Candidate Master Regulators Governing Neuropathology of Schizophrenia

J. Knowles, J. Duan, O. Evgrafov, 2017 .

Polygenic Adaptation Underlies Evolution of Brain Structures and Behavioral Traits

Dan J Stein, B. Stranger, J. Knowles, 2019, European Neuropsychopharmacology.

Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

Warren W. Kretzschmar, Robert M. Maier, P. O’Reilly, 2020, Molecular psychiatry.

Applications of the pipeline environment for visual informatics and genomics computations

Arthur W. Toga, Carl Kesselman, Ivo D. Dinov, 2011, BMC Bioinformatics.

A screen of SLC1A1 for OCD‐related alleles

S. Rauch, D. Murphy, B. Greenberg, 2010, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls.

Melissa J. Green, Janice M. Fullerton, Robert C. Thompson, 2019, Biological psychiatry.

Rare Copy Number Variants in NRXN1 and CNTN6 Increase Risk for Tourette Syndrome

N. Freimer, M. Nöthen, W. McMahon, 2016, Neuron.

Parental bonding and hoarding in obsessive-compulsive disorder.

S. E. Stewart, D. Murphy, B. Greenberg, 2017, Comprehensive psychiatry.

De novo variants in GREB1L are associated with non-syndromic inner ear malformations and deafness

D. Raible, J. Knowles, M. Huentelman, 2018, Human Genetics.

Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium

John P. Rice, Warren W. Kretzschmar, Robert M. Maier, 2017, Biological Psychiatry.

Polygenic risk prediction: why and when out-of-sample prediction R2 can exceed SNP-based heritability.

John P. Rice, Warren W. Kretzschmar, Robert M. Maier, 2023, American journal of human genetics.

A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts.

John P. Rice, Warren W. Kretzschmar, Robert M. Maier, 2021, Biological psychiatry.

Genome-wide Burden of Rare Short Deletions Is Enriched in Major Depressive Disorder in Four Cohorts

John P. Rice, M. Rietschel, J. Potash, 2019, Biological Psychiatry.

risk variants and refine the genetic architecture ofmajor depressive disorder

Li, Katharina, Warren W. Kretzschmar, 2022 .

No genetic linkage or association between a functional promoter polymorphism in the monoamine oxidase-A gene and panic disorder

S. Hodge, D. Klein, A. Fyer, 2000, Molecular Psychiatry.

Association and linkage analysis of candidate genes GRP, GRPR, CRHR1, and TACR1 in panic disorder

M. Weissman, A. Fyer, J. Knowles, 2009, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Genome-wide association study of pediatric obsessive-compulsive traits: shared genetic risk between traits and disorder

Dan J Stein, S. E. Stewart, R. Delorme, 2021, Translational Psychiatry.

When tractography meets tracer injections: a systematic study of trends and variation sources of diffusion-based connectivity

Yonggang Shi, Arthur W Toga, Dogu Baran Aydogan, 2018, Brain Structure and Function.

Clinical correlates and genetic linkage of social and communication difficulties in families with obsessive–compulsive disorder: Results from the OCD Collaborative Genetics Study

S. E. Stewart, S. Rauch, D. Murphy, 2014, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Gene expression in patient-derived neural progenitors provide insights into neurodevelopmental aspects of schizophrenia

C. Pato, M. Pato, H. Medeiros, 2017 .

Dorsal Amygdala Neurotrophin-3 Decreases Anxious Temperament in Primates

N. Kalin, W. Block, J. Knowles, 2019, Biological Psychiatry.

Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder

N. Craddock, S. Mccarroll, H. Nicolini, 2017, Translational Psychiatry.

Multivariate analysis of anxiety disorders yields further evidence of linkage to chromosomes 4q21 and 7p in panic disorder families

A. Fyer, M. Weissman, J. Knowles, 2012, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

Madeline, Melissa J. Green, Janice M. Fullerton, 2017 .

Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

John P. Rice, Warren W. Kretzschmar, Robert M. Maier, 2020, Biological Psychiatry.