Jennifer B Pierson

发表

The Comprehensive in Vitro Proarrhythmia Assay (CiPA) initiative - Update on progress.

T. Colatsky, B. Fermini, G. Gintant, 2016, Journal of pharmacological and toxicological methods.

Can non‐clinical repolarization assays predict the results of clinical thorough QT studies? Results from a research consortium

Jean-Pierre Valentin, Gary A Gintant, Todd Wisialowski, 2018, British journal of pharmacology.

Evaluating Uncertainty to Strengthen Epidemiologic Data for Use in Human Health Risk Assessments

Jennifer B Pierson, J. Wright, I. Burstyn, 2014, Environmental health perspectives.

International Multisite Study of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Drug Proarrhythmic Potential Assessment

Daniel C Millard, G. Gintant, Jennifer B Pierson, 2018, Cell reports.

Cross-Site Reliability of Human Induced Pluripotent stem cell-derived Cardiomyocyte Based Safety Assays Using Microelectrode Arrays: Results from a Blinded CiPA Pilot Study

Qianyu Dang, Gary Gintant, Hong Shi, 2018, Toxicological sciences : an official journal of the Society of Toxicology.

The Challenges of Predicting Drug-Induced QTc Prolongation in Humans

G. Gintant, Jennifer B Pierson, C. Garnett, 2022, Toxicological sciences : an official journal of the Society of Toxicology.

Publisher Correction: Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells

B. Fermini, G. Gintant, Jennifer B Pierson, 2020, Scientific Reports.

Considerations for an In Vitro, Cell-Based Testing Platform for Detection of Drug-Induced Inotropic Effects in Early Drug Development. Part 2: Designing and Fabricating Microsystems for Assaying Cardiac Contractility With Physiological Relevance Using Human iPSC-Cardiomyocytes

G. Gintant, Jennifer B Pierson, B. Berridge, 2019, Front. Pharmacol..

University of Birmingham Changes in the metabolome and microRNA levels in biological fluids might represent biomarkers of neurotoxicity:

W. Tong, W. Slikker, Jennifer B Pierson, 2017 .

CO Can We Panelize Seizure?

Jennifer B Pierson, Ruth Roberts, I. Suzuki, 2020 .

Repolarization studies using human stem cell-derived cardiomyocytes: Validation studies and best practice recommendations.

G. Gintant, Jennifer B Pierson, S. Stoelzle-Feix, 2020, Regulatory toxicology and pharmacology : RTP.

A public-private consortium advances cardiac safety evaluation: achievements of the HESI Cardiac Safety Technical Committee.

Jennifer B Pierson, S. Pettit, B. Berridge, 2013, Journal of pharmacological and toxicological methods.

Non-Lethal Endotoxin Injection: A Rat Model of Hypercoagulability

K. Thompson, Jennifer B Pierson, H. Ellinger-Ziegelbauer, 2017, PloS one.

Can We Panelize Seizure?

Jennifer B Pierson, Ruth Roberts, I. Suzuki, 2020, Toxicological sciences : an official journal of the Society of Toxicology.

Use of the ZDF rat to model dietary fat induced hypercoagulability is limited by progressive and fatal nephropathy.

Jennifer B Pierson, A. E. Schultze, A. Chiang, 2020, Journal of pharmacological and toxicological methods.

Echocardiographic and hemodynamic indices of myocardial contractility simultaneously evaluated in telemetered beagle dogs: A HESI-sponsored cross-company evaluation.

Eric I. Rossman, Jennifer B Pierson, N. Polissar, 2020, Journal of pharmacological and toxicological methods.

The evaluation of drug-induced changes in cardiac inotropy in dogs: Results from a HESI-sponsored consortium.

Eric I. Rossman, Jennifer L. Doyle, Jennifer B Pierson, 2015, Journal of pharmacological and toxicological methods.

Considerations for an In Vitro, Cell-Based Testing Platform for Detection of Adverse Drug-Induced Inotropic Effects in Early Drug Development. Part 1: General Considerations for Development of Novel Testing Platforms

Tanja Zabka, John Koerner, Gary Gintant, 2019, Front. Pharmacol..

Electrophysiological characterization of drug response in hSC-derived cardiomyocytes using voltage-sensitive optical platforms.

Godfrey L. Smith, Graham T Dempsey, G. Gintant, 2019, Journal of pharmacological and toxicological methods.

Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells

B. Fermini, G. Gintant, Jennifer B Pierson, 2020, Scientific Reports.

An evaluation of the utility of LVdP/dt40, QA interval, LVdP/dtmin and Tau as indicators of drug-induced changes in contractility and lusitropy in dogs.

Eric I. Rossman, Jennifer B Pierson, J. Koerner, 2017, Journal of pharmacological and toxicological methods.

Public Health Laboratories and Radiological Readiness

Jennifer B Pierson, M. Latshaw, Deborah Kim, 2011, Disaster Medicine and Public Health Preparedness.

Title : Cross-Site Reliability of Human Induced Pluripotent Stem-Cell Derived Cardiomyocyte Based Safety Assays using Microelectrode Arrays : Results from a Blinded CiPA Pilot Study Running Title : CiPA hSC-CM MEA Pilot Study

G. Gintant, Jennifer B Pierson, C. Strock, 2018 .

The incidence of spontaneous arrhythmias in telemetered beagle dogs, Göttingen Minipigs and Cynomolgus non-human primates: A HESI consortium retrospective analysis.

Matthew M. Abernathy, Eric I. Rossman, Jennifer B Pierson, 2023, Journal of pharmacological and toxicological methods.

A Proof-of-Concept Evaluation of JTPc and Tp-Tec as Proarrhythmia Biomarkers in Preclinical Species: A Retrospective Analysis by an HESI-Sponsored Consortium

Matthew M. Abernathy, Eric I. Rossman, Jennifer B Pierson, 2018, International journal of toxicology.

Cardiac contractility: Correction strategies applied to telemetry data from a HESI-sponsored consortium.

Jennifer B Pierson, E. Troncy, S. Authier, 2017, Journal of pharmacological and toxicological methods.

Assessing drug-induced long QT and proarrhythmic risk using human stem cell-derived cardiomyocytes in a Ca2+ imaging assay: Evaluation of 28 CiPA compounds at three test sites.

Jennifer B Pierson, I. Kopljar, R. Kettenhofen, 2019, Toxicological sciences : an official journal of the Society of Toxicology.