N. Shastri

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Discrete proteolytic intermediates in the MHC class I antigen processing pathway and MHC I-dependent peptide trimming in the ER.

P. Paz, N. Brouwenstijn, R. Perry, 1999, Immunity.

Editorial overview: Antigen processing and presentation: Where cellular immunity begins.

J. Yewdell, N. Shastri, 2015, Current opinion in immunology.

Leucine-tRNA Initiates at CUG Start Codons for Protein Synthesis and Presentation by MHC Class I

N. Shastri, S. R. Starck, T. Pan, 2012, Science.

The final touches make perfect the peptide-MHC class I repertoire.

N. Shastri, T. Kanaseki, G. Hammer, 2007, Immunity.

Major Histocompatibility Class I Molecules Can Present Cryptic Translation Products to T-cells (*)

N. Shastri, Vu Nguyen, F. Gonzalez, 1995, The Journal of Biological Chemistry.

Amino acid residues distinct from the determinant region can profoundly affect activation of T cell clones by related antigens.

N. Shastri, A. Miller, E. Sercarz, 1986, Journal of immunology.

Unanticipated Antigens: Translation Initiation at CUG with Leucine

N. Shastri, S. Malarkannan, T. Horng, 2004, PLoS biology.

Translation from the 5′ untranslated region shapes the integrated stress response

Peter Walter, Lei Wang, Keling Chen, 2016, Science.

ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum

N. Shastri, T. Serwold, F. Gonzalez, 2002, Nature.

The molecular and functional characterization of a dominant minor H antigen, H60.

N. Shastri, S. Malarkannan, T. Horng, 1998, Journal of immunology.

Brain microvessel cross-presentation is a hallmark of experimental cerebral malaria

F. Ginhoux, N. Shastri, C. Poh, 2013, EMBO molecular medicine.

ERAAP and Tapasin Independently Edit the Amino and Carboxyl Termini of MHC Class I Peptides

N. Nagarajan, N. Shastri, A. Rockwood, 2013, The Journal of Immunology.

Constitutive Display of Cryptic Translation Products by MHC Class I Molecules

N. Shastri, C. Kang, S. Schwab, 2003, Science.

Mousepox detected in a research facility: case report and failure of mouse antibody production testing to identify Ectromelia virus in contaminated mouse serum.

S. Griffey, N. Shastri, E. James, 2009, Comparative medicine.

Apparent MHC-independent stimulation of CD8+ T cells in vivo during latent murine gammaherpesvirus infection.

N. Shastri, M. Blackman, D. Woodland, 1999, Journal of Immunology.

Gammaherpesvirus Infection T Cells In Vivo During Latent Murine + CD 8 Apparent MHC-Independent Stimulation of Woodland and

N. Shastri, M. Blackman, D. Woodland, 1999 .

Differences that matter: major cytotoxic T cell-stimulating minor histocompatibility antigens.

N. Brouwenstijn, N. Shastri, S. Malarkannan, 2000, Immunity.

ERAAP Shapes the Peptidome Associated with Classical and Nonclassical MHC Class I Molecules

N. Nagarajan, N. Shastri, C. Perreault, 2016, The Journal of Immunology.

Class I Major Histocompatibility Complex Presentation of Antigens That Escape from the Parasitophorous Vacuole of Toxoplasma gondii

N. Shastri, B. Striepen, M. Gubbels, 2005, Infection and Immunity.

Efficient MHC class I presentation by controlled intracellular trafficking of antigens in octaarginine-modified liposomes.

Hideyoshi Harashima, Kentaro Kogure, N. Shastri, 2008, Molecular therapy : the journal of the American Society of Gene Therapy.

Positional cloning and molecular characterization of an immunodominant cytotoxic determinant of the mouse H3 minor histocompatibility complex.

N. Shastri, D. Roopenian, A. Zuberi, 1998, Immunity.

Bacterial surface proteins recognized by CD4+ T cells during murine infection with Listeria monocytogenes.

N. Shastri, D. Campbell, 1998, Journal of immunology.

Class I MHC presentation of exogenous soluble antigen via macropinocytosis in bone marrow macrophages.

N. Shastri, A. Prescott, L. Hewlett, 1995, Immunity.

Basic science232. Certolizumab pegol prevents pro-inflammatory alterations in endothelial cell function

H. L. Wright, R. Moots, T. Spector, 2012 .

In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides

N. Shastri, G. Hammer, F. Gonzalez, 2007, Nature Immunology.

Continuous Effector CD8(+) T Cell Production in a Controlled Persistent Infection Is Sustained by a Proliferative Intermediate Population.

N. Shastri, J. P. Gosling, G. Lythe, 2016, Immunity.

Minors held by majors: the H13 minor histocompatibility locus defined as a peptide/MHC class I complex.

P. Paz, N. Shastri, D. Roopenian, 1997, Immunity.

Construction and destruction of MHC class I in the peptide-loading complex

N. Shastri, G. Hammer, 2007, Nature Immunology.

Alloreactive CD8+ T cells can recognize unusual, rare, and unique processed peptide/MHC complexes.

N. Shastri, S. Malarkannan, G. Adair, 1996, Journal of immunology.

The mouse mammary tumor virus env gene is the source of a CD8+ T-cell-stimulating peptide presented by a major histocompatibility complex class I molecule in a murine thymoma.

N. Shastri, S. Malarkannan, T. Serwold, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Distinguishing Self from Nonself: Immunogenicity of the Murine H47 Locus Is Determined by a Single Amino Acid Substitution in an Unusual Peptide1

N. Shastri, D. Roopenian, P. Eden, 2001, The Journal of Immunology.

Introducing endogenous antigens into the major histocompatibility complex (MHC) class II presentation pathway. Both Ii mediated inhibition and enhancement of endogenous peptide/MHC class II presentation require the same Ii domains

N. Shastri, K. Frauwirth, 2001, Immunology.

Identification of a CD4+ T cell-stimulating antigen of pathogenic bacteria by expression cloning

N. Shastri, D. Campbell, S. Sanderson, 1995, The Journal of experimental medicine.

Biochemical Analysis of Naturally Processed Antigenic Peptides Presented by MHC Class I Molecules.

N. Shastri, T. Kanaseki, 2019, Methods in molecular biology.

Biochemical analysis of naturally processed antigenic peptides presented by MHC class I molecules.

N. Shastri, T. Kanaseki, 2013, Methods in molecular biology.

Discrimination Motifs Determine Self-Nonself Lacking Conventional MHC Binding Anchor Differing by a Single Methyl Group and How H13 Histocompatibility Peptides

N. Shastri, S. Almo, D. Roopenian, 2001 .

A peptide-based fluorescent probe images ERAAP activity in cells and in high throughput assays.

N. Shastri, N. Murthy, Yumiao Zhang, 2018, Chemical communications.

MHC Class I Molecules Quality of Processed Peptides Presented by Regulates Associated with Antigen Processing Endoplasmic Reticulum Aminopeptidase

N. Shastri, T. Kanaseki, 2008 .

Rearranged beta T cell receptor genes in a helper T cell clone specific for lysozyme: no correlation between V beta and MHC restriction.

L. Hood, T. Hunkapiller, N. Shastri, 1985, Cell.

Molecular analysis of skewed Tcra-V gene use in T-cell receptor β-chain transgenic mice

N. Shastri, R. Barth, K. Natarajan, 1997, Immunogenetics.

Non-classical MHC class Ib-restricted cytotoxic T cells monitor antigen processing in the endoplasmic reticulum

N. Nagarajan, N. Shastri, F. Gonzalez, 2012, Nature Immunology.

A Ligand for the Murine NK Activation Receptor Ly-49D: Activation of Tolerized NK Cells from β2-Microglobulin- Deficient Mice1

N. Shastri, W. Yokoyama, K. Iizuka, 2002, The Journal of Immunology.

Second Class Minors

N. Shastri, H. Sahara, 2003, The Journal of experimental medicine.

Tyrosyl phosphorylation and activation of MAP kinases by p56lck.

R. Aebersold, N. Shastri, J. Watts, 1992, Science.

Identification of CD8+ T-cell-stimulating antigen genes in cDNA libraries.

N. Shastri, S. Malarkannan, L. Mendoza, 2001, Methods in molecular biology.

LacZ inducible, antigen/MHC-specific T cell hybrids.

N. Shastri, S. Sanderson, Sarah Sanderson, 1994, International immunology.

Non-conventional sources of peptides presented by MHC class I

N. Shastri, S. R. Starck, S. Starck, 2011, Cellular and Molecular Life Sciences.

Mutation of the invariant chain transmembrane region inhibits II degradation, prolongs association with MHC class II, and selectively disrupts antigen presentation.

N. Shastri, K. Frauwirth, 2001, Cellular immunology.

Presentation of Cryptic Peptides by MHC Class I Is Enhanced by Inflammatory Stimuli

N. Shastri, S. R. Starck, Sharanya Prasad, 2016, The Journal of Immunology.

The choice between two distinct T cell determinants within a 23-amino acid region of lysozyme depends on their structural context.

N. Shastri, A. Miller, E. Sercarz, 1986, Journal of immunology.

In vivo targeting of dendritic cells for activation of cellular immunity using vaccine carriers based on pH-responsive microparticles.

N. Shastri, J. Fréchet, E. James, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Transnuclear CD8 T cells specific for the immunodominant epitope Gra6 lower acute‐phase Toxoplasma gondii burden

N. Shastri, H. Ploegh, Nagisa Yoshida, 2016, Immunology.

The Choice of T‐Cell Epitopes Utilized on a Protein Antigen Depends on Multiple Factors Distant from, as well as at the Determinant Site

N. Shastri, E. Sercarz, Alexander Miller, 1987, Immunological Reviews.

Impact of regulated secretion on antiparasitic CD8 T cell responses.

N. Shastri, J. Boothroyd, M. Reese, 2014, Cell reports.

The promiscuous development of an unconventional Qa1b-restricted T cell population

N. Shastri, S. Chan, E. Robey, 2022, bioRxiv.

The expressed T cell repertoire is hierarchical: the precise focus of lysozyme-specific T cell clones is dependent upon the structure of the immunogen.

N. Shastri, A. Miller, E. Sercarz, 1984, The Journal of molecular and cellular immunology : JMCI.

A limited region within hen egg-white lysozyme serves as the focus for a diversity of T cell clones.

N. Shastri, A. Miller, E. Sercarz, 1984, Journal of immunology.

Microglobulin-Deficient Mice 2 β Cells from Receptor Ly-49 D : Activation of Tolerized NK A Ligand for the Murine NK Activation

N. Shastri, W. Yokoyama, K. Iizuka, 2002 .

IL-3 enhances both presentation of exogenous particulate antigen in association with class I major histocompatibility antigen and generation of primary tumor-specific cytolytic T lymphocytes.

N. Shastri, A. McAdam, J. Frelinger, 1998, Journal of immunology.

T Lymphocytes Generation of Primary Tumor-Specific Cytolytic Major Histocompatibility Antigen and Particulate Antigen in Association with Class I IL-3 Enhances Both Presentation of Exogenous

N. Shastri, A. McAdam, J. Frelinger, 1998 .

Coping with loss of perfection in the MHC class I peptide repertoire.

N. Shastri, N. Blanchard, 2008, Current opinion in immunology.

Immune surveillance for ERAAP dysfunction.

N. Nagarajan, N. Shastri, 2013, Molecular immunology.

Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages

N. Shastri, A. Diefenbach, A. Jamieson, 2000, Nature Immunology.

Ia-transfected L-cell fibroblasts present a lysozyme peptide but not the native protein to lysozyme-specific T cells.

L. Hood, N. Shastri, B. Malissen, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Structure-function analysis of Ia molecules: in-phase insertion mutagenesis of the amino-terminal domain of the E beta k polypeptide chain.

N. Shastri, B. Malissen, F. Letourneur, 1988, Biochimie.

Interleukin 3 enhances cytotoxic T lymphocyte development and class I major histocompatibility complex "re-presentation" of exogenous antigen by tumor-infiltrating antigen-presenting cells.

N. Shastri, D. Penney, J. Frelinger, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Virus-infected Cells I Peptide Repertoire in Normal and the Composition and Structure of Mhc Class Associated with Antigen Processing Defines Endoplasmic Reticulum Aminopeptidase

N. Nagarajan, N. Shastri, D. Crockett, 2022 .

Requirement for association of p56 lck with CD4 in antigen-specific signal transduction in T cells

N. Shastri, N. Glaichenhaus, D. Littman, 1991, Cell.

Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library

C. Janeway, N. Shastri, L. Wen, 1999, Nature Medicine.

Peptides, Scrambled and Stitched

N. Shastri, 2006, Science.

Structure-function relationship among T-cell receptors specific for lysozyme peptides bound to Ab or Abm-12 molecules.

L. Hood, N. Shastri, J. Kobori, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Immune surveillance obstructed by viral mRNA

N. Shastri, S. R. Starck, S. Cardinaud, 2008, Proceedings of the National Academy of Sciences.

A novel strategy for the generation of T cell lines lacking expression of endogenous alpha- and/or beta-chain T cell receptor genes.

N. Shastri, J. Allison, N. Glaichenhaus, 1991, Journal of immunology.

The Toxoplasma gondii Peptide AS15 Elicits CD4 T Cells That Can Control Parasite Burden

N. Shastri, S. Chan, E. Robey, 2012, Infection and Immunity.

The Influence of the Molecular Context of T Cell Determinants and the non-MHC Genetic Context of the H-2b Genes on the Immunogenicity of Lysozyme

N. Shastri, A. Miller, S. Sadegh-Nasseri, 1986 .

I-A(k) and I-E(k) present 2 unique sets of epitopes on a small peptide of hen lysozyme (HEL)

N. Shastri, E. Sercarz, Alexander Miller, 1985 .

Apparent MHC-independent stimulation of CD8+ T cells in vivo during latent murine gammaherpesvirus infection.

N. Shastri, M. Blackman, D. Woodland, 1999, Journal of immunology.

The Molecular Context of a Determinant Influences Its Dominant Expression in a T Cell Response Hierarchy Through “Fine Processing”

N. Shastri, E. Sercarz, Alexander Miller, 1986 .

The ER Aminopeptidases, ERAP1 and ERAP2, synergize to self-modulate their respective activities

N. Shastri, S. Sadegh-Nasseri, J. A. López de Castro, 2022, Frontiers in Immunology.

Cross‐presentation of peptides from intracellular pathogens by MHC class I molecules

N. Shastri, N. Blanchard, 2010, Annals of the New York Academy of Sciences.

Intracellular calcium dependence of gene expression in single T lymphocytes.

P. Negulescu, N. Shastri, M. Cahalan, 1994, Proceedings of the National Academy of Sciences of the United States of America.

A macromolecular delivery vehicle for protein-based vaccines: Acid-degradable protein-loaded microgels

Jean M. J. Fréchet, Jun Kunisawa, N. Shastri, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Antigen processing and recognition Edited by James McCluskey. Boca Raton: CRC Press. (1991). 257 pp. $139.95

N. Shastri, 1992, Cell.

Quantitative Analysis of the Immune Response to Mouse Non-MHC Transplantation Antigens In Vivo: The H60 Histocompatibility Antigen Dominates Over All Others

N. Shastri, S. Malarkannan, E. Choi, 2001, The Journal of Immunology.

The molecular genetics of the T-cell antigen receptor and T-cell antigen recognition.

L. Hood, N. Shastri, M. Kronenberg, 1986, Annual review of immunology.

Processing of the preparations of beta-subunit of human chorionic gonadotropin for minimization of cross-reactivity with human luteinizing hormone.

N. Shastri, S. Ramakrishnan, G. P. Talwar, 1976, Contraception.

Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes

N. Shastri, L. Coscoy, E. Robey, 2022, bioRxiv.

Kinetics of antibody response in animals injected with processed beta-HCG conjugated to tetanus toxoid (Pr- beta-HCG-TT).

N. Shastri, G. P. Talwar, M. Salahuddin, 1976, Contraception.

Immunological properties of dinitrophenyl derivatives of beta-subunit of the human chorionic gonadotropin.

N. Shastri, G. P. Talwar, M. Salahuddin, 1976, Contraception.

Measurement of ligand-induced activation in single viable T cells using the lacZ reporter gene.

N. Shastri, J. Karttunen, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Differential affinity of anti-Pr-β-hCG-TT antibodies for hCG and hLH

N. Shastri, G. P. Talwar, M. Salahuddin, 1978 .

Important Role of the Carrier in the Induction of Antibody Response Without Freund's Complete Adjuvant Against a “Self” Peptide Luteinizing Hormone‐Releasing Hormone (LHRH) *

N. Shastri, G. P. Talwar, S. Manhar, 1981 .

Differences between the discriminatory activity of antisera raised against the total gonadotropins and the Pr-beta-hCG-TT for neutralization of hCG and LH action.

N. Shastri, G. P. Talwar, T. Chapekar, 1978, Contraception.

A Distinct Translation Initiation Mechanism Generates Cryptic Peptides for Immune Surveillance

N. Shastri, R. Roberts, X. Qi, 2008, PloS one.

Nowhere to hide: unconventional translation yields cryptic peptides for immune surveillance

N. Shastri, S. Starck, 2016, Immunological reviews.

Leucine-tRNA Initiates at CUG Start Codons for Protein Synthesis and Presentation by MHC Class I

N. Shastri, T. Pan, V. Jiang, 2012, Science.

The Synthesis of Truncated Polypeptides for Immune Surveillance and Viral Evasion

N. Shastri, S. Cardinaud, P. Chandra, 2010, PloS one.

All the peptides that fit: the beginning, the middle, and the end of the MHC class I antigen‐processing pathway

N. Shastri, T. Serwold, J. Kunisawa, 2005, Immunological reviews.

Producing nature's gene-chips: the generation of peptides for display by MHC class I molecules.

N. Shastri, T. Serwold, S. Schwab, 2002, Annual review of immunology.

Presentation of out-of-frame peptide/MHC class I complexes by a novel translation initiation mechanism.

N. Shastri, S. Malarkannan, T. Horng, 1999, Immunity.

Delivery of protein to the cytosol of macrophages using Escherichia coli K‐12

N. Shastri, D. Portnoy, D. Higgins, 1999, Molecular microbiology.

SPAS-1 (stimulator of prostatic adenocarcinoma-specific T cells)/SH3GLB2: A prostate tumor antigen identified by CTLA-4 blockade

N. Shastri, J. Allison, N. Greenberg, 2008, Proceedings of the National Academy of Sciences.

Murine cytomegalovirus downregulates ERAAP & induces an unconventional T cell response to self

N. Shastri, L. Coscoy, E. Robey, 2022, bioRxiv.

The nonclassical immune surveillance for ERAAP function.

N. Shastri, Joshua A Taylor, J. D. Peske, 2021, Current opinion in immunology.

Antigen Processing in the Endoplasmic Reticulum Is Monitored by Semi-Invariant αβ TCRs Specific for a Conserved Peptide–Qa-1b MHC Class Ib Ligand

N. Shastri, Yuxin Yin, F. Gonzalez, 2017, The Journal of Immunology.

ERAAP synergizes with MHC class I molecules to make the final cut in the antigenic peptide precursors in the endoplasmic reticulum.

N. Shastri, T. Kanaseki, G. Hammer, 2006, Immunity.

The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules

N. Shastri, D. Cado, G. Hammer, 2006, Nature Immunology.

Immunodominant, protective response to the parasite Toxoplasma gondii requires antigen processing in the endoplasmic reticulum

N. Shastri, M. Schaeffer, E. Robey, 2008, Nature Immunology.

Single T cell probes for antigen/MHC expression.

N. Shastri, 1995, Current opinion in immunology.

Casting a wider net: Immunosurveillance by nonclassical MHC molecules

Timothy A. Gondré-Lewis, E. Adams, Y. Chien, 2019, PLoS pathogens.

Rearranged β t cell receptor genes in a helper t cell clone specific for lysozyme: No correlation between Vβ and MHC restriction

L. Hood, T. Hunkapiller, N. Shastri, 1985, Cell.

Acid-degradable particles for protein-based vaccines: enhanced survival rate for tumor-challenged mice using ovalbumin model.

Young Jik Kwon, Jun Kunisawa, Lana Lau, 2004, Bioconjugate chemistry.

Neonatal T-cell tolerance to minimal immunogenic peptides is caused by clonal inactivation

N. Shastri, E. Sercarz, S. Wilbur, 1986, Nature.

Endoplasmic Reticulum Aminopeptidase Associated with Antigen Processing Regulates Quality of Processed Peptides Presented by MHC Class I Molecules1

N. Shastri, T. Kanaseki, 2008, The Journal of Immunology.

Hsp90alpha chaperones large C-terminally extended proteolytic intermediates in the MHC class I antigen processing pathway.

N. Shastri, J. Kunisawa, 2006, Immunity.

The group II chaperonin TRiC protects proteolytic intermediates from degradation in the MHC class I antigen processing pathway.

Jun Kunisawa, N. Shastri, J. Kunisawa, 2003, Molecular cell.

MHC class I molecules can direct proteolytic cleavage of antigenic precursors in the endoplasmic reticulum.

N. Brouwenstijn, N. Shastri, T. Serwold, 2001, Immunity.

ER aminopeptidases generate a unique pool of peptides for MHC class I molecules

N. Shastri, T. Serwold, S. Gaw, 2001, Nature Immunology.

Generation of antigen-specific, lacZ-inducible T-cell hybrids.

N. Shastri, S. Malarkannan, L. Mendoza, 2001, Methods in molecular biology.

Specific proteolytic cleavages limit the diversity of the pool of peptides available to MHC class I molecules in living cells.

N. Shastri, T. Serwold, 1999, Journal of immunology.

Expression of endogenous peptide-major histocompatibility complex class II complexes derived from invariant chain-antigen fusion proteins.

N. Shastri, K. Frauwirth, S. Sanderson, 1995, Proceedings of the National Academy of Sciences of the United States of America.

The role of MHC class I molecules in the generation of endogenous peptide/MHC complexes.

N. Shastri, S. Malarkannan, D. Buchholz, 1995, Journal of immunology.

Endogenous generation and presentation of the ovalbumin peptide/Kb complex to T cells.

N. Shastri, F. Gonzalez, 1993, Journal of immunology.

Detection of rare antigen-presenting cells by the lacZ T-cell activation assay suggests an expression cloning strategy for T-cell antigens.

N. Shastri, S. Sanderson, J. Karttunen, 1992, Proceedings of the National Academy of Sciences of the United States of America.

All Others Histocompatibility Antigen Dominates Over Transplantation Antigens In Vivo : The H 60 Response to Mouse Non-MHC Quantitative Analysis of the Immune

N. Shastri, S. Malarkannan, E. Choi, 2001 .

Location of the CD8 T Cell Epitope within the Antigenic Precursor Determines Immunogenicity and Protection against the Toxoplasma gondii Parasite

N. Shastri, V. Vasseur, Mark J. Brown, 2013, PLoS pathogens.

A rare cryptic translation product is presented by Kb major histocompatibility complex class I molecule to alloreactive T cells

N. Shastri, S. Malarkannan, M. Afkarian, 1995, The Journal of experimental medicine.

Enhanced antigen presentation and CTL activity by transduction of mature rather than immature dendritic cells with octaarginine-modified liposomes.

Hideyoshi Harashima, Kentaro Kogure, N. Shastri, 2009, Journal of controlled release : official journal of the Controlled Release Society.

Critical Role of Endoplasmic Reticulum Aminopeptidase 1 in Determining the Length and Sequence of Peptides Bound and Presented by HLA–B27

N. Shastri, T. Elliott, R. Fischer, 2014, Arthritis & rheumatology.

Elimination of T‐cell‐receptor β‐chain diversity in transgenic mice restricts antigen‐specific but not alloreactive responses

N. Shastri, C. Baecher-Allan, R. Barth, 1997, Immunology.

Diversity of T-Cell Receptor Structures Specific for Minimal Peptide/Ia Determinants: Implications for Immune Response Gene Defects

L. Hood, N. Shastri, J. Kobori, 1986 .

Induction of tolerance to one determinant on a synthetic peptide does not affect the response to a second linked determinant. Implications for the mechanism of neonatal tolerance induction

N. Shastri, E. Sercarz, G. Gammon, 1986, The Journal of experimental medicine.

Distinct recognition phenotypes exist for T cell clones specific for small peptide regions of proteins. Implications for the mechanisms underlying major histocompatibility complex-restricted antigen recognition and clonal deletion models of immune response gene defects

N. Shastri, A. Miller, E. Sercarz, 1985, The Journal of experimental medicine.

The Role of T Cells in Obesity-Associated Inflammation and Metabolic Disease

N. Shastri, Chan-Su Park, Chan-su Park, 2022, Immune network.

Ia molecule-associated selectivity in T cell recognition of a 23-amino- acid peptide of lysozyme

N. Shastri, A. Miller, E. Sercarz, 1986, The Journal of experimental medicine.

Needles in haystacks: identifying specific peptide antigens for T cells.

N. Shastri, 1996, Current opinion in immunology.

Cotransfer of the Ed alpha and Ad beta genes into L cells results in the surface expression of a functional mixed-isotype Ia molecule.

L. Hood, N. Shastri, B. Malissen, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Reading within the lines: naturally processed peptides displayed by MHC class I molecules.

P. Paz, N. Shastri, T. Serwold, 1998, Current opinion in immunology.

Presentation without Proteolytic Cleavage of Endogenous Precursors in the MHC Class I Antigen Processing Pathway (*)

N. Shastri, P. Scott, Daniel Buchholz, 1995, The Journal of Biological Chemistry.

Presentation of endogenous peptide/MHC class I complexes is profoundly influenced by specific C-terminal flanking residues.

N. Shastri, T. Serwold, F. Gonzalez, 1995, Journal of immunology.

Endoplasmic Reticulum Aminopeptidase Associated with Antigen Processing Defines the Composition and Structure of MHC Class I Peptide Repertoire in Normal and Virus-Infected Cells

N. Nagarajan, N. Shastri, D. Crockett, 2010, The Journal of Immunology.

How H13 Histocompatibility Peptides Differing by a Single Methyl Group and Lacking Conventional MHC Binding Anchor Motifs Determine Self-Nonself Discrimination1

H. Grey, N. Shastri, S. Almo, 2002, The Journal of Immunology.

Discrimination Motifs Determine Self-Nonself Lacking Conventional MHC Binding Anchor Differing by a Single Methyl Group and How H13 Histocompatibility Peptides

H. Grey, N. Shastri, S. Almo, 2001 .

Topological journey of parasite-derived antigens for presentation by MHC class I molecules.

N. Shastri, N. Blanchard, 2010, Trends in immunology.

Bacterial Proteins Can Be Processed by Macrophages in a Transporter Associated with Antigen Processing-Independent, Cysteine Protease-Dependent Manner for Presentation by MHC Class I Molecules1

N. Shastri, T. Serwold, D. Campbell, 2000, The Journal of Immunology.

Class I Molecules Cysteine Protease-Dependent Manner for with Antigen Processing-Independent , Macrophages in a Transporter Associated Bacterial Proteins Can Be Processed

N. Shastri, D. Campbell, 1999 .

Generation of naturally processed peptide/MHC class I complexes is independent of the stability of endogenously synthesized precursors.

N. Shastri, V. Nguyen, S. Goth, 1996, Journal of immunology.

The Major Histocompatibility Complex and the T Cell Repertoire

N. Shastri, E. Sercarz, J. Cogswell, 1987 .

The use of LCMV-specific T cell hybridomas for the quantitative analysis of MHC class I restricted antigen presentation.

N. Shastri, K. Schwarz, M. van den Broek, 2000, Journal of immunological methods.

Both human and mouse cells expressing H-2Kb and ovalbumin process the same peptide, SIINFEKL.

I. Graef, H. Rammensee, N. Shastri, 1993, Cellular immunology.

The multiplicity of domains on a protein antigen affecting immune responsiveness

N. Shastri, E. Sercarz, 1984 .

Hierarchical Relationships Among Epitopes: Only Certain Potentially Utilizable Epitopes on Protein Antigens are Actually Presented in a Particular Haplotype

N. Shastri, R. Maizels, E. Sercarz, 1983 .

Monitoring peptide processing for MHC class I molecules in the endoplasmic reticulum.

N. Nagarajan, N. Shastri, T. Kanaseki, 2014, Current opinion in immunology.

The promiscuous development of an unconventional Qa1b-restricted T cell population

N. Shastri, L. Coscoy, S. Chan, 2023, bioRxiv.

Commensal Bacteria Maintain a Qa-1b-restricted Unconventional CD8+ T Population in Gut Epithelium

N. Shastri, J. D. Peske, E. Robey, 2023, bioRxiv.

CD1d- and MR1-Restricted T Cells in Sepsis

N. Shastri, S. Haeryfar, J. McCormick, 2015, Front. Immunol..

Determination of a Key Antigen for Immunological Intervention To Target the Latent Stage of Toxoplasma gondii

N. Shastri, Yasuhiro Suzuki, A. Tiwari, 2017, The Journal of Immunology.

Commensal Bacteria Maintain a Qa-1b-restricted Unconventional CD8+ T Population in Gut Epithelium

N. Shastri, J. D. Peske, E. Robey, 2023, bioRxiv.

A peptide puzzle

N. Shastri, J. Guan, 2018, eLife.

Immune surveillance obstructed by viral mRNA

N. Shastri, S. Cardinaud, S. Starck, 2008, Proceedings of the National Academy of Sciences.

Cross‐presentation of peptides from intracellular pathogens by MHC class I molecules

N. Shastri, N. Blanchard, 2010, Annals of the New York Academy of Sciences.

Commensal bacteria maintain a Qa-1b-restricted unconventional CD8+ T population in gut epithelium

N. Shastri, J. D. Peske, E. Robey, 2023, bioRxiv.

A peptide-based fluorescent probe images ERAAP activity in cells and in high throughput assays.

N. Shastri, N. Murthy, Yumiao Zhang, 2018, Chemical communications.