T. Elliott

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Transporter associated with antigen processing.

T. Elliott, T. Elliott, 1997, Advances in immunology.

R. Dwek, I. Wilson, P. Cresswell, 2001, Science.

Stress proteins, infection, and immune surveillance

R. Young, T. Elliott, R. Young, 1989, Cell.

A Mechanistic Basis for the Co-evolution of Chicken Tapasin and Major Histocompatibility Complex Class I (MHC I) Proteins*

T. Elliott, J. Kaufman, Anthony P. Williams, 2013, The Journal of Biological Chemistry.

Analysis of the interaction of antibodies with immunoglobulin idiotypes on neoplastic B lymphocytes: implications for immunotherapy.

T. Elliott, M. Glennie, H. McBride, 1987, Journal of immunology.

Naturally Processed HLA Class II Peptides Reveal Highly Conserved Immunogenic Flanking Region Sequence Preferences That Reflect Antigen Processing Rather Than Peptide-MHC Interactions1

Maria V. Tejada-Simon, Tim Elliott, A. Hill, 2001, The Journal of Immunology.

TAPBPR alters MHC class I peptide presentation by functioning as a peptide exchange catalyst

S. Stevanović, T. Elliott, J. Trowsdale, 2015, eLife.

Viral antigen mediated NKp46 activation of NK cells results in tumor rejection via NK-DC crosstalk

T. Elliott, A. Bateman, E. James, 2012, Oncoimmunology.

Cholesteryl esters stabilize human CD1c conformations for recognition by self-reactive T cells

T. Elliott, J. Essex, B. Jakobsen, 2016, Proceedings of the National Academy of Sciences.

How does TAP associate with MHC class I molecules?

T. Elliott, 1997, Immunology today.

Breast cancer is a promising target for vaccination using cancer-testis antigens known to elicit immune responses

T. Elliott, Mark Taylor, L. Bolton, 2007, Breast Cancer Research.

Assembly and antigen-presenting function of MHC class I molecules in cells lacking the ER chaperone calreticulin.

T. Elliott, M. Howarth, M. Michalak, 2002, Immunity.

Passage of transmissible cancers in the Tasmanian devil is due to a dominant, shared peptide motif and a limited repertoire of MHC-I allotypes

Sri H. Ramarathinam, T. Elliott, P. Skipp, 2020, bioRxiv.

Recognition of carbohydrate by major histocompatibility complex class I- restricted, glycopeptide-specific cytotoxic T lymphocytes

R. Dwek, T. Elliott, A. McMichael, 1994, The Journal of experimental medicine.

An improved assembly assay for peptide binding to HLA-B*2705 and H-2K(k) class I MHC molecules.

T. Elliott, J. Haurum, M. Andersen, 1997, Journal of immunological methods.

Depletion of CD25+ regulatory cells uncovers immune responses to shared murine tumor rejection antigens

T. Elliott, F. Powrie, A. Gallimore, 2002, European journal of immunology.

II-Restricted Cytoplasmic Antigens Indirect Presentation of MHC Class Th Cell Responses by Regulating + CD4Associated with Antigen Processing Control Reticulum-Associated Aminopeptidase Proteasomes, TAP, and Endoplasmic

T. Elliott, L. Kaer, D. Roopenian, 2011 .

Lectin-deficient calreticulin retains full functionality as a chaperone for class I histocompatibility molecules.

T. Elliott, U. Brockmeier, David B. Williams, 2008, Molecular biology of the cell.

The oxidoreductase ERp57 efficiently reduces partially folded in preference to fully folded MHC class I molecules

T. Elliott, Andrew R. Osborne, S. Powis, 2002, The EMBO journal.

Evidence for successive peptide binding and quality control stages during MHC class I assembly

T. Elliott, Jonathan W. Lewis, 1998, Current Biology.

Phosphorylated peptides can be transported by TAP molecules, presented by class I MHC molecules, and recognized by phosphopeptide-specific CTL.

T. Elliott, J. Neefjes, J. Zeuthen, 1999, Journal of immunology.

Direct evidence for conformational dynamics in major histocompatibility complex class I molecules

T. Elliott, P. Skipp, A. van Hateren, 2017, The Journal of Biological Chemistry.

Plasticity of empty major histocompatibility complex class I molecules determines peptide-selector function

T. Elliott, A. van Hateren, Alistair Bailey, 2015, Molecular immunology.

The Role of Calnexin and Calreticulin in MHC Class I Assembly

T. Elliott, R. Adhikari, 2003 .

The optimization of peptide cargo bound to MHC class I molecules by the peptide‐loading complex

T. Elliott, Anthony P. Williams, 2005, Immunological reviews.

Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope

T. Elliott, A. Sewell, G. Dolton, 2019, The Journal of Biological Chemistry.

The Kinetics of Association of Peptides with MHC Class 1 Molecules

T. Elliott, V. Cerundolo, A. Townsend, 1993 .

Naturally processed peptides

T. Elliott, V. Cerundolo, A. Townsend, 1990, Nature.

More images that yet fresh images Beget.

T. Elliott, 2009, Immunity.

Structural and Functional Changes of the Invariant NKT Clonal Repertoire in Early Rheumatoid Arthritis

C. Cooper, T. Elliott, C. Woelk, 2015, The Journal of Immunology.

An assay for peptide binding to HLA-Cw*0102.

T. Elliott, J. Zeuthen, J. Haurum, 1999, Tissue antigens.

Absence of Tapasin Alters Immunodominance against a Lymphocytic Choriomeningitis Virus Polytope

T. Elliott, Anthony P. Williams, E. James, 2009, The Journal of Immunology.

Peptide antagonism as a mechanism for NK cell activation

T. Elliott, M. Purbhoo, F. Claas, 2010, Proceedings of the National Academy of Sciences.

CD8+ T-cell cross-competition is governed by peptide–MHC class I stability

T. Elliott, I. Galea, C. Ottensmeier, 2011, European journal of immunology.

A commentary on the Nobel Prize award for Physiology or Medicine – for the discovery of cancer therapy by inhibition of negative immune regulation

T. Elliott, S. L. Hill, Peter W. M. Johnson, 2019, The Biochemist.

Cytotoxic T lymphocytes recognize a reconstituted class I histocompatibility antigen (HLA-A2) as an allogeneic target molecule.

T. Elliott, H. Eisen, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Allorecognition of purified major histocompatibility complex glycoproteins by cytotoxic T lymphocytes.

T. Elliott, H. Eisen, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Association of the human invariant chain with H‐2 Db class I molecules

T. Elliott, V. Cerundolo, J. Bastin, 1992, European journal of immunology.

The Clonal Invariant NKT Cell Repertoire in People with Type 1 Diabetes Is Characterized by a Loss of Clones Expressing High-Affinity TCRs

T. Elliott, Joseph P. Sanderson, R. Holt, 2017, The Journal of Immunology.

Cholesteryl esters stabilise human CD1c conformations for recognition by self-reactive T cells

Rajendra, Schumann, T. Elliott, 2015 .

The Human HLA-A*0201 Allele, Expressed in Hamster Cells, Is Not a High-Affinity Receptor for Adenovirus Type 5 Fiber

T. Elliott, I. Kirby, G. Santis, 1999, Journal of Virology.

Tapasin-mediated editing of the MHC I immunopeptidome is epitope specific and dependent on peptide off-rate, abundance, and level of tapasin expression

T. Elliott, N. Dalchau, P. Duriez, 2022, Frontiers in Immunology.

Lymphoblastoid cells express HLA‐B27 homodimers both intracellularly and at the cell surface following endosomal recycling

T. Elliott, A. McMichael, P. Bowness, 2003, European journal of immunology.

Tapasin enhances MHC class I peptide presentation according to peptide half-life.

T. Elliott, A. Tolstrup, M. Howarth, 2004, Proceedings of the National Academy of Sciences of the United States of America.

The role of MHC I protein dynamics in tapasin and TAPBPR-assisted immunopeptidome editing.

T. Elliott, A. van Hateren, 2021, Current opinion in immunology.

Protein Plasticity and Peptide Editing in the MHC I Antigen Processing Pathway.

T. Elliott, A. van Hateren, 2018, Biochemistry.

Identification of novel Tapasin polymorphisms and linkage disequilibrium to MHC class I alleles

T. Elliott, R. Houlston, K. Welsh, 2000, Immunogenetics.

Common variable immunodeficiency is associated with a functional deficiency of invariant natural killer T cells.

T. Elliott, B. Grimbacher, Anthony P. Williams, 2014, The Journal of allergy and clinical immunology.

Assembly of MHC class I molecules analyzed in vitro

T. Elliott, V. Cerundolo, A. Townsend, 1990, Cell.

Synthesis of major histocompatibility complex class I binding glycopeptides

R. Dwek, T. Elliott, A. Lellouch, 1995 .

Recognition of Carbohydrate by Major Histocompatibility Complex Class 1-restricted, Glyeopeptide-specific

R. Dwek, T. Elliott, A. McMichael, 2003 .

The influence of CD25+ cells on the generation of immunity to tumour cell lines in mice.

T. Elliott, G. Screaton, A. Simon, 2004, Novartis Foundation symposium.

Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex

T. Elliott, J. Trowsdale, A. Townsend, 1992, Nature.

CD1b-restricted GEM T cell responses are modulated by Mycobacterium tuberculosis mycolic acid meromycolate chains

T. Elliott, J. Essex, B. Marshall, 2017, Proceedings of the National Academy of Sciences.

The cell biology of major histocompatibility complex class I assembly: towards a molecular understanding.

T. Elliott, N. Dalchau, A. Phillips, 2010, Tissue antigens.

Peptide-MHC Interactions Reflect Antigen Processing Rather Than Flanking Region Sequence Preferences That Reveal Highly Conserved Immunogenic Naturally Processed HLA Class II Peptides

Tim Elliott, V. Adrian, T. Elliott, 2001 .

Proteasomes, TAP, and Endoplasmic Reticulum-Associated Aminopeptidase Associated with Antigen Processing Control CD4+ Th Cell Responses by Regulating Indirect Presentation of MHC Class II-Restricted Cytoplasmic Antigens

T. Elliott, D. Roopenian, D. Scott, 2011, The Journal of Immunology.

Two Polymorphisms Facilitate Differences in Plasticity between Two Chicken Major Histocompatibility Complex Class I Proteins

T. Elliott, A. van Hateren, Alistair Bailey, 2014, PloS one.

Genes encoded in the major histocompatibility complex affecting the generation of peptides for TAP transport

T. Elliott, J. Trowsdale, V. Cerundolo, 1995, European journal of immunology.

The immunopeptidomes of two transmissible cancers and their host have a common, dominant peptide motif

Sri H. Ramarathinam, T. Elliott, P. Skipp, 2021, Immunology.

The newly-arisen Devil facial tumour disease 2 (DFT2) reveals a mechanism for the emergence of a contagious cancer

T. Elliott, Y. Kwon, G. Thomas, 2018, eLife.

Recognition of out‐of‐frame major histocompatibility complex class I‐restricted epitopes in vivo

T. Elliott, H. Bodmer, Alain Townsend, 1996, European journal of immunology.

Advancing our knowledge of antigen processing with computational modelling, structural biology, and immunology.

T. Elliott, J. Essex, S. Turner, 2023, Biochemical Society transactions.

HLA tapasin independence: broader peptide repertoire and HIV control

J. Goedert, M. Carrington, B. Walker, 2020, Proceedings of the National Academy of Sciences.

Processing and Presentation of Glycoproteins in the MHC Class I and II Antigen Presentation Pathways

T. Elliott, M. Howarth, D. Golgher, 2022 .

Characterization of the Class I MHC Peptidome Resulting From DNCB Exposure of HaCaT Cells

T. Elliott, B. Nicholas, P. Skipp, 2020, Toxicological sciences : an official journal of the Society of Toxicology.

Presentation of Cytosolic Glycosylated Peptides by Human Class I Major Histocompatibility Complex Molecules in Vivo

T. Elliott, J. Neefjes, J. Zeuthen, 1999, The Journal of experimental medicine.

Poor correspondence between predicted and experimental binding of peptides to class I MHC molecules.

T. Elliott, J. Zeuthen, T Elliott, 2000, Tissue antigens.

MHC-restricted T cell responses against posttranslationally modified peptide antigens.

T. Elliott, J. Haurum, M. Andersen, 2001, Advances in immunology.

Bone marrow transplantation for MHC class I deficiency corrects T-cell immunity but dissociates natural killer cell repertoire formation from function

T. Elliott, S. Khakoo, A. Mant, 2016, The Journal of allergy and clinical immunology.

Optimization of the MHC class I peptide cargo is dependent on tapasin.

James McCluskey, Chen Au Peh, Anthony W Purcell, 2002, Immunity.

Induction and Exhaustion of Lymphocytic Choriomeningitis Virus–specific Cytotoxic T Lymphocytes Visualized Using Soluble Tetrameric Major Histocompatibility Complex Class I–Peptide Complexes

R. Zinkernagel, T. Elliott, A. Plückthun, 1998, The Journal of experimental medicine.

Processing of major histocompatibility class I-restricted antigens in the endoplasmic reticulum

T. Elliott, V. Cerundolo, A. Townsend, 1995, The Journal of experimental medicine.

Peptide selection by class I molecules of the major histocompatibility complex

T. Elliott, A. McMichael, P. Driscoll, 1993, Current Biology.

A method to quantify binding of unlabeled peptides to class I MHC molecules and detect their allele specificity.

T. Elliott, V. Cerundolo, A. Townsend, 1993, Journal of immunological methods.

Short peptides assist the folding of free class I heavy chains in solution

T. Elliott, V. Cerundolo, A. Townsend, 1992, European journal of immunology.

Structural requirements for the peptide‐induced conformational change of free major histocompatibility complex class I heavy chains

T. Elliott, V. Cerundolo, J. Elvin, 1992, European journal of immunology.

Peptide-induced conformational change of the class I heavy chain

T. Elliott, V. Cerundolo, A. Townsend, 1991, Nature.

The processing of antigens delivered as DNA vaccines

T. Elliott, M. Howarth, 2004, Immunological reviews.

The cell biology of MHC class I antigen presentation.

T. Elliott, A Williams, C A Peh, 2002, Tissue antigens.

Glycan-regulated Antigen Processing of a Protein in the Endoplasmic Reticulum Can Uncover Cryptic Cytotoxic T Cell Epitopes

T. Elliott, P. Wood, 1998, The Journal of experimental medicine.

A Soluble Major Histocompatibility Complex Class I Peptide-binding Platform Undergoes a Conformational Change in Response to Peptide Epitopes*

T. Elliott, M. Kojima, A. Glithero, 1998, The Journal of Biological Chemistry.

Point mutations in the α2 domain of HLA-A2.1 define a functionally relevant interaction with TAP

T. Elliott, J. Neefjes, Jonathan W. Lewis, 1996, Current Biology.

Immunopeptidomic analysis of influenza A virus infected human tissues identifies internal proteins as a rich source of HLA ligands

T. Elliott, B. Nicholas, P. Skipp, 2021, bioRxiv.

Application of the pMHC Array to Characterise Tumour Antigen Specific T Cell Populations in Leukaemia Patients at Disease Diagnosis

Hans-Georg Rammensee, Demin Li, Ken I. Mills, 2015, PloS one.

Ligand Selection and Trafficking for MHC I

T. Elliott, A. V. Hateren, A. Hateren, 2016 .

Crystal structures of two H-2Db/glycopeptide complexes suggest a molecular basis for CTL cross-reactivity.

R. Dwek, T. Elliott, M. Wormald, 1999, Immunity.

Kinetics of Abacavir-Induced Remodelling of the Major Histocompatibility Complex Class I Peptide Repertoire

T. Elliott, J. McCluskey, N. Mifsud, 2021, Frontiers in Immunology.

TAPBPR bridges UDP-glucose:glycoprotein glucosyltransferase 1 onto MHC class I to provide quality control in the antigen presentation pathway

S. Stevanović, T. Elliott, N. Trautwein, 2017, eLife.

Recent advances in Major Histocompatibility Complex (MHC) class I antigen presentation: Plastic MHC molecules and TAPBPR-mediated quality control

T. Elliott, A. van Hateren, Alistair Bailey, 2017, F1000Research.

Selector function of MHC I molecules is determined by protein plasticity

T. Elliott, N. Dalchau, S. Emmott, 2015, Scientific Reports.

Increased Valency of Conserved-mosaic Vaccines Enhances the Breadth and Depth of Epitope Recognition.

T. Elliott, Bette Korber, T. Hanke, 2016, Molecular therapy : the journal of the American Society of Gene Therapy.

The pathway of cross‐presentation is influenced by the particle size of phagocytosed antigen

T. Elliott, A. Mant, Anthony P. Williams, 2012, Immunology.

Peptide anchor residue glycosylation: effect on class I major histocompatibility complex binding and cytotoxic T lymphocyte recognition

R. Dwek, T. Elliott, A. McMichael, 1995, European journal of immunology.

The Inhibitory Receptor NKG2A Determines Lysis of Vaccinia Virus-Infected Autologous Targets by NK Cells1

P. Parham, T. Elliott, S. Khakoo, 2006, The Journal of Immunology.

Target cell lysis by cytotoxic T lymphocytes that lack detectable hemolytic perforin activity.

T. Elliott, N. Allbritton, C. Verret, 1988, Journal of immunology.

Critical Role of Endoplasmic Reticulum Aminopeptidase 1 in Determining the Length and Sequence of Peptides Bound and Presented by HLA–B27

N. Shastri, T. Elliott, R. Fischer, 2014, Arthritis & rheumatology.

Assembly and export of MHC class I peptide ligands.

T. Elliott, S. Powis, A. Antoniou, 2003, Current opinion in immunology.

An Immunodominant MHC Class II-Restricted Tumor Antigen Is Conformation Dependent and Binds to the Endoplasmic Reticulum Chaperone, Calreticulin1

T. Elliott, D. Pardoll, M. Edidin, 2001, The Journal of Immunology.

Differential Suppression of Tumor-Specific CD8+ T Cells by Regulatory T Cells

T. Elliott, F. Korangy, B. J. Van den Eynde, 2010, The Journal of Immunology.

Regulatory T Cells + CD 8 Differential Suppression of Tumor-Specific

T. Elliott, F. Korangy, B. Eynde, 2010 .

In Vivofor Activating Naive CD8+ T Cells Multiple Antigen-Specific Processing

J. Yewdell, T. Elliott, R. Brutkiewicz, 2013 .

A Mechanistic Model for Predicting Cell Surface Presentation of Competing Peptides by MHC Class I Molecules

Andrew Phillips, Peter V. Coveney, Neil Dalchau, 2018, Front. Immunol..

The quantity of naturally processed peptides stably bound by HLA-A*0201 is significantly reduced in the absence of tapasin.

T. Elliott, M. Howarth, P. Bowness, 2001, Tissue antigens.

Peptide-independent stabilization of MHC class I molecules breaches cellular quality control

T. Elliott, H. Hanenberg, F. Momburg, 2014, Journal of Cell Science.

Faculty Opinions recommendation of Intramembrane proteolysis of signal peptides: an essential step in the generation of HLA-E epitopes.

T. Elliott, 2002 .

Tapasin shapes immunodominance hierarchies according to the kinetic stability of peptide – MHC class I complexes

T. Elliott, M. Howarth, F. Stevenson, 2008, European journal of immunology.

The Crystal Structure of H-2Db Complexed with a Partial Peptide Epitope Suggests a Major Histocompatibility Complex Class I Assembly Intermediate*

T. Elliott, M. Kojima, E. Jones, 2006, Journal of Biological Chemistry.

Fluctuations in TCR and pMHC interactions regulate T cell activation

T. Elliott, B. MacArthur, Omer Dushek, 2021, bioRxiv.

Calreticulin‐dependent recycling in the early secretory pathway mediates optimal peptide loading of MHC class I molecules

T. Elliott, E. Ghanem, M. Al-Balushi, 2009, The EMBO journal.

Lectin purified human class I MHC-derived peptides: evidence for presentation of glycopeptides in vivo.

H. Rammensee, S. Stevanović, T. Elliott, 2000, Tissue antigens.

Integration of Avidity and Differentiation is enabled by CD8+ T-cell sensing of IFN-γ

T. Elliott, A. Gérard, Lion F K Uhl, 2023, bioRxiv.

Targets by NK Cells Lysis of Vaccinia Virus-Infected Autologous The Inhibitory Receptor NKG 2 A Determines Khakoo

P. Parham, T. Elliott, S. Khakoo, 2005 .

Generation of a functional, soluble tapasin protein from an alternatively spliced mRNA

T. Elliott, B. Gao, A. Williams, 2004, Genes and Immunity.

VaccinesPeptide Motifs: Implications for Cancer Cytotoxic T Cell Responses Against Defined DNA Fusion Vaccine Designed to Induce

T. Elliott, J. Rice, F. Stevenson, 2001 .

Dynamically Driven Allostery in MHC Proteins: Peptide-Dependent Tuning of Class I MHC Global Flexibility

T. Elliott, F. Noé, L. Hellman, 2019, Front. Immunol..

ERp57 Does Not Require Interactions with Calnexin and Calreticulin to Promote Assembly of Class I Histocompatibility Molecules, and It Enhances Peptide Loading Independently of Its Redox Activity*

T. Elliott, G. Kozlov, K. Gehring, 2009, Journal of Biological Chemistry.

Polymer microarrays: identification of substrates for phagocytosis assays.

Mark Bradley, Guilhem Tourniaire, T. Elliott, 2006, Biomaterials.

Faculty Opinions recommendation of F pocket flexibility influences the tapasin dependence of two differentially disease-associated MHC Class I proteins.

T. Elliott, A. V. Hateren, 2017 .

Tapasin dependence of major histocompatibility complex class I molecules correlates with their conformational flexibility

M. Zacharias, T. Elliott, J. Trowsdale, 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

A Peptide Filtering Relation Quantifies MHC Class I Peptide Optimization

Luca Cardelli, Stephen Emmott, Neil Dalchau, 2011, PLoS Comput. Biol..

Quantitative and qualitative iNKT repertoire associations with disease susceptibility and outcome in macaque tuberculosis infection.

T. Elliott, A. Singhania, M. Tebruegge, 2017, Tuberculosis.

Molecular machinations of the MHC-I peptide loading complex.

T. Elliott, A. Purcell, 2008, Current opinion in immunology.

The 'chop-and-change' of MHC class I assembly

Tim Elliott, T. Elliott, 2006, Nature Immunology.

The Complex Route to MHC Class I-Peptide Complexes

T. Elliott, J. Neefjes, 2006, Cell.

stably bound by HLA-A * 0201 is significantly

T. Elliott, M. Howarth, P. Bowness, 2002 .

Visualising tapasin- and TAPBPR-assisted editing of major histocompatibility complex class-I immunopeptidomes.

T. Elliott, A. van Hateren, 2023, Current opinion in immunology.

The newly-arisen Devil facial tumour disease 2 (DFT2) reveals a mechanism for the emergence of a contagious cancer

T. Elliott, Y. Kwon, G. Thomas, 2018, eLife.

Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope

T. Elliott, A. Sewell, G. Dolton, 2019, The Journal of Biological Chemistry.

Solid-phase synthesis of 89 polyamine-based cationic lipids for DNA delivery to mammalian cells.

T. Elliott, M. Bradley, M. Howarth, 2004, Chemistry.

Structural and Functional Changes of the Invariant NKT Clonal Repertoire in Early Rheumatoid Arthritis

T. Elliott, C. Woelk, M. Edwards, 2015, The Journal of Immunology.

Mathematical immunology: two polymorphisms facilitate differences in plasticity between two chicken major histocompatibility complex class I proteins

T. Elliott, Alistair Bailey, J. Werner, 2014 .

Cytotoxic Tlymphocytes recognize areconstituted class I histocompatibili ty antigen (HLA-A2) asanallogeneic target molecule

T. Elliott, H. Eisen, 1990 .