J. Senz

发表

Mutation of FOXL2 in granulosa-cell tumors of the ovary.

Ryan D. Morin, A. deFazio, D. Bowtell, 2009, The New England journal of medicine.

Subtype‐specific mutation of PPP2R1A in endometrial and ovarian carcinomas

A. Mes-Masson, S. Shah, D. Huntsman, 2011, The Journal of pathology.

ARID1A mutations in endometriosis-associated ovarian carcinomas.

Richard A. Moore, S. Fereday, D. Bowtell, 2010, The New England journal of medicine.

Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

Ryan D. Morin, Richard A. Moore, Trevor J Pugh, 2009, Nature.

Mutation Discovery in Regions of Segmental Cancer Genome Amplifications with CoNAn-SNV: A Mixture Model for Next Generation Sequencing of Tumors

Allen D. Delaney, M. Marra, M. Hirst, 2012, PloS one.

Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer

Ali Bashashati, Alexandre Bouchard-Côté, Richard A. Moore, 2016, Nature Genetics.

Cancer‐associated somatic DICER1 hotspot mutations cause defective miRNA processing and reverse‐strand expression bias to predominantly mature 3p strands through loss of 5p strand cleavage

D. Huntsman, J. Senz, M. Anglesio, 2013, The Journal of pathology.

Germline E-cadherin mutations in familial lobular breast cancer

P. Miron, D. Huntsman, J. Senz, 2007, Journal of Medical Genetics.

Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling

Ali Bashashati, Thomas Zeng, Stephen Yip, 2013, The Journal of pathology.

Development and Validation of the Gene Expression Predictor of High-grade Serous Ovarian Carcinoma Molecular SubTYPE (PrOTYPE)

M. Pike, P. Fasching, A. Talhouk, 2020, Clinical Cancer Research.

Molecular characterization of mucinous ovarian tumours supports a stratified treatment approach with HER2 targeting in 19% of carcinomas

A. Tinker, S. Fereday, D. Bowtell, 2013, The Journal of pathology.

Cross-Cancer Genome-Wide Association Study of Endometrial Cancer and Epithelial Ovarian Cancer Identifies Genetic Risk Regions Associated with Risk of Both Cancers

A. Whittemore, M. Beckmann, P. Fasching, 2020, Cancer Epidemiology, Biomarkers & Prevention.

Prognostic gene expression signature for high-grade serous ovarian cancer

P. Fasching, A. Talhouk, J. Chang-Claude, 2020, Annals of oncology : official journal of the European Society for Medical Oncology.

Significance of p53 immunostaining in mesothelial proliferations and correlation with TP53 mutation status

D. Huntsman, J. Senz, A. Churg, 2021, Modern Pathology.

Redefinition of familial intestinal gastric cancer: clinical and genetic perspectives

D. Huntsman, J. Senz, F. Roviello, 2020, Journal of Medical Genetics.

Endometrial Cancer Molecular Risk Stratification is Equally Prognostic for Endometrioid Ovarian Carcinoma

A. Talhouk, S. Leung, A. Bashashati, 2020, Clinical Cancer Research.

Hereditary diffuse gastric cancer

D. Huntsman, J. Senz, W. Rubinstein, 2008, Cancer.

Molecular subclassification of vulvar squamous cell carcinoma: reproducibility and prognostic significance of a novel surgical technique

J. Senz, J. McAlpine, C. Gilks, 2022, International Journal of Gynecological Cancer.

Identical TP53 mutations provide evidence that late‐recurring tubo‐ovarian high‐grade serous carcinomas do not represent new peritoneal primaries

J. Senz, C. Gilks, M. Anglesio, 2017, Histopathology.

Genomic consequences of aberrant DNA repair mechanisms stratify ovarian cancer histotypes

Ali Bashashati, Richard A. Moore, Gavin Ha, 2017, Nature Genetics.

CDH1/E-cadherin germline mutations in early-onset gastric cancer

D. Huntsman, J. Senz, S. Gallinger, 2006, Journal of Medical Genetics.

Significance of p53 and presence of differentiated vulvar intra-epithelial neoplasia (dVIN) at resection margin in early stage human papillomavirus-independent vulvar squamous cell carcinoma

S. Leung, D. Huntsman, J. Senz, 2022, International Journal of Gynecological Cancer.

Hereditary diffuse gastric cancer: association with lobular breast cancer

Janine Senz, Henry T. Lynch, Wylie Burke, 2007, Familial Cancer.

Mechanisms of monozygotic (MZ) twinning: A possible role for the cell adhesion molecule, E‐cadherin

D. Huntsman, J. Senz, F. Bamforth, 2003, American journal of medical genetics. Part A.

Germline mutations in CDH1 are infrequent in women with early-onset or familial lobular breast cancers

O. Olopade, M. Southey, P. Miron, 2010, Journal of Medical Genetics.

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O. Olopade, M. Southey, P. Miron, 2022 .

Substrate and positional specificities of human and mouse lecithin-cholesterol acyltransferases. Studies with wild type recombinant and chimeric enzymes expressed in vitro.

J. Senz, M. Liu, P. Subbaiah, 1994, Biochimica et biophysica acta.

Type-Specific Cell Line Models for Type-Specific Ovarian Cancer Research

S. Shah, D. Huntsman, J. Senz, 2013, PloS one.

DICER1 and FOXL2 Mutation Status Correlates With Clinicopathologic Features in Ovarian Sertoli-Leydig Cell Tumors

D. Huntsman, J. Senz, P. Clement, 2019, The American journal of surgical pathology.

SNVMix: predicting single nucleotide variants from next-generation sequencing of tumors

Kevin P. Murphy, Sohrab P. Shah, Ryan D. Morin, 2010, Bioinform..

FOXL2 Mutation is Absent in Uterine Tumors Resembling Ovarian Sex Cord Tumors

D. Huntsman, J. Senz, C. Gilks, 2015, The American journal of surgical pathology.

FOXL2 Is a Sensitive and Specific Marker for Sex Cord-Stromal Tumors of the Ovary

D. Huntsman, J. Senz, S. Kalloger, 2011, The American journal of surgical pathology.

Using next‐generation sequencing for the diagnosis of rare disorders: a family with retinitis pigmentosa and skeletal abnormalities

Steven J. M. Jones, B. Fernandez, T. Nielsen, 2011, The Journal of pathology.

MicroRNA Profiling of BRCA1/2 Mutation-Carrying and Non-Mutation-Carrying High-Grade Serous Carcinomas of Ovary

Andrew H. Beck, David Huntsman, Janine Senz, 2009, PloS one.

deFuse: An Algorithm for Gene Fusion Discovery in Tumor RNA-Seq Data

Süleyman Cenk Sahinalp, Malachi Griffith, Sohrab P. Shah, 2011, PLoS Comput. Biol..

Hereditary Diffuse Gastric Cancer Syndrome: CDH1 Mutations and Beyond.

B. Fernandez, A. Talhouk, S. Shah, 2015, JAMA oncology.

β‐Catenin (CTNNB1) gene amplification: A new mechanism of protein overexpression in cancer

H. Masoudi, D. Huntsman, J. Senz, 2005, Genes, chromosomes & cancer.

The NMD mRNA surveillance pathway downregulates aberrant E-cadherin transcripts in gastric cancer cells and in CDH1 mutation carriers

D. Huntsman, J. Senz, R. Seruca, 2008, Oncogene.

Targeted deep sequencing of mucinous ovarian tumors reveals multiple overlapping RAS-pathway activating mutations in borderline and cancerous neoplasms

Jesse S. Voss, D. Huntsman, J. Senz, 2015, BMC Cancer.

A clinically applicable molecular-based classification for endometrial cancers

A. Talhouk, S. Leung, D. Huntsman, 2015, British Journal of Cancer.

Multifocal endometriotic lesions associated with cancer are clonal and carry a high mutation burden

Yi Kan Wang, A. Bashashati, M. Marra, 2015, The Journal of pathology.

Correction: Type-Specific Cell Line Models for Type-Specific Ovarian Cancer Research

S. Shah, D. Huntsman, J. Senz, 2013, PloS one.

BRCA1 and BRCA2 mutations correlate with TP53 abnormalities and presence of immune cell infiltrates in ovarian high-grade serous carcinoma

Sohrab P Shah, Jiarui Ding, Janine Senz, 2012, Modern Pathology.

Characterization of a Recurrent Germ Line Mutation of the E-Cadherin Gene: Implications for Genetic Testing and Clinical Management

D. Huntsman, J. Senz, J. Norton, 2005, Clinical Cancer Research.

Recurrent somatic DICER1 mutations in nonepithelial ovarian cancers.

Steven J. M. Jones, Anthony P. Fejes, P. Sorensen, 2012, The New England journal of medicine.

Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant.

P. Meltzer, L. Coin, S. Davis, 2016, American journal of human genetics.

Founder and recurrent CDH1 mutations in families with hereditary diffuse gastric cancer.

B. Fernandez, D. Huntsman, P. Pharoah, 2007, JAMA.

review of genetic screening criteria gastric cancer: assessment of 42 new families and Germline E-cadherin mutations in hereditary diffuse

W. Foulkes, J. Senz, C. Greenberg, 2006 .

Germline E-cadherin mutations in hereditary diffuse gastric cancer: assessment of 42 new families and review of genetic screening criteria

W. Foulkes, Y. Butterfield, C. Caldas, 2004, Journal of Medical Genetics.

LINE-1 retrotransposon-mediated DNA transductions in endometriosis associated ovarian cancers.

Yi Kan Wang, A. Bashashati, S. Shah, 2017, Gynecologic oncology.

The Oncogenic Roles of DICER1 RNase IIIb Domain Mutations in Ovarian Sertoli-Leydig Cell Tumors12

Fan Mo, D. Huntsman, J. Senz, 2015, Neoplasia.

Germline CDH1 deletions in hereditary diffuse gastric cancer families

S. Chin, C. Caldas, D. Huntsman, 2009, Human molecular genetics.

Correction: Type-Specific Cell Line Models for Type-Specific Ovarian Cancer Research

S. Shah, D. Huntsman, J. Senz, 2013, PLoS ONE.

A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia

Rohini Rau-Murthy, Jinghui Zhang, Kenneth Offit, 2013, Nature Genetics.

Adult‐type granulosa cell tumor of the ovary: a FOXL2‐centric disease

Yi Kan Wang, A. Bashashati, H. Horlings, 2021, The journal of pathology. Clinical research.

Confirmation of ProMisE: A simple, genomics‐based clinical classifier for endometrial cancer

A. Talhouk, S. Leung, D. Huntsman, 2017, Cancer.

In‐depth molecular profiling of the biphasic components of uterine carcinosarcomas

D. Huntsman, J. Senz, B. Clarke, 2015, The journal of pathology. Clinical research.

The Specificity of the FOXL2 c.402C>G Somatic Mutation: A Survey of Solid Tumors

D. Huntsman, J. Monahan, J. Senz, 2009, PloS one.

Cancer‐Associated Mutations in Endometriosis without Cancer

L. Wood, K. Kinzler, B. Vogelstein, 2017, The New England journal of medicine.

Use of mutation profiles to refine the classification of endometrial carcinomas

Thomas Zeng, Martin Hirst, Kane Tse, 2012, The Journal of pathology.

Classification of Vulvar Squamous Cell Carcinoma and Precursor Lesions by p16 and p53 Immunohistochemistry: Considerations, Caveats and an Algorithmic Approach.

J. Senz, C. Chow, J. McAlpine, 2023, Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.

Allele-specific CDH1 downregulation and hereditary diffuse gastric cancer.

D. Huntsman, J. Senz, R. Seruca, 2010, Human molecular genetics.

Recurrent DICER1 hotspot mutations in endometrial tumours and their impact on microRNA biogenesis

Jamie Rosner, D. Huntsman, J. Senz, 2015, The Journal of pathology.

Molecular subtypes of clear cell carcinoma of the endometrium: Opportunities for prognostic and predictive stratification.

S. Leung, J. Senz, C. Gilks, 2020, Gynecologic oncology.

Endometrial Carcinomas with POLE Exonuclease Domain Mutations Have a Favorable Prognosis

A. Talhouk, S. Leung, D. Huntsman, 2016, Clinical Cancer Research.

Synchronous Endometrial and Ovarian Carcinomas: Evidence of Clonality.

Yi Kan Wang, A. Bashashati, S. Shah, 2015, Journal of the National Cancer Institute.

Grade and Estrogen Receptor Expression Identify a Subset of No Specific Molecular Profile Endometrial Carcinomas at a Very Low Risk of Disease-Specific Death.

A. Talhouk, S. Leung, D. Huntsman, 2023, Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.

Quantification of epigenetic and genetic 2nd hits in CDH1 during hereditary diffuse gastric cancer syndrome progression.

J. Yokota, D. Huntsman, J. Senz, 2009, Gastroenterology.

Molecular analysis suggests oligoclonality and metastasis of endometriosis lesions across anatomically defined subtypes.

M. Köbel, J. Senz, M. Anglesio, 2022, Fertility and sterility.

Ovarian and endometrial endometrioid carcinomas have distinct CTNNB1 and PTEN mutation profiles

S. Shah, Jiarui Ding, D. Huntsman, 2014, Modern Pathology.

DICER1 hot‐spot mutations in ovarian gynandroblastoma

D. Huntsman, J. Senz, C. Gilks, 2018, Histopathology.

FOXL2 molecular testing in ovarian neoplasms: diagnostic approach and procedural guidelines

D. Huntsman, J. Senz, C. Gilks, 2013, Modern Pathology.

Variability in endometrial carcinoma pathology practice: opportunities for improvement with molecular classification

A. Talhouk, S. Leung, A. Tinker, 2022, Modern Pathology.

4 Refining pathologic interpretation of endometrial carcinomas: lessons learned from a nationwide study in a new era of molecular classification

J. Senz, J. McAlpine, B. Gilks, 2020 .

Rare APC promoter 1B variants in gastric cancer kindreds unselected for fundic gland polyposis

D. Huntsman, J. Senz, K. Dixon, 2020, Gut.

[Hereditary diffuse gastric cancer (HDGC): presentation of a family with a new mutation of the CDH1 gene].

D. Huntsman, J. Senz, H. Lynch, 2007, Acta gastroenterologica Latinoamericana.

Is endometriosis metastasizing? Shared somatic alterations suggest common origins across endometriotic lesions

M. Köbel, J. Senz, M. Anglesio, 2020, Geburtshilfe und Frauenheilkunde.

p53-Abnormal "Fields of Dysplasia" in Human Papillomavirus-Independent Vulvar Squamous Cell Carcinoma Impacts Margins and Recurrence Risk.

D. Huntsman, J. Senz, J. McAlpine, 2023, Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.

A clinically applicable molecular-based classification for endometrial cancers

A. Talhouk, S. Leung, D. Huntsman, 2015, British Journal of Cancer.

Molecular classification defines outcomes and opportunities in young women with endometrial carcinoma.

A. Talhouk, S. Leung, J. Senz, 2019, Gynecologic oncology.

231 Molecular subclassification of vulvar squamous cell carcinoma: prognostic significance and reproducibility

J. Senz, C. Gilks, J. Huvila, 2021, Vaginal and vulvar cancer.

Polymerase Epsilon Exonuclease Domain Mutations in Ovarian Endometrioid Carcinoma

D. Huntsman, M. Köbel, J. Senz, 2015, International Journal of Gynecologic Cancer.

O005/#638 ProMisE-2: a one step DNA-based endometrial cancer molecular classifier

A. Talhouk, S. Leung, A. Bashashati, 2022, Oral Abstracts (Regular and Late-Breaking Submission).

KRAS mutations and endometriosis burden of disease

J. Senz, M. Anglesio, K. Lawrenson, 2023, The journal of pathology. Clinical research.

Harmonized molecular classification; assessment of a single-test ProMisE NGS tool.

A. Talhouk, S. Leung, A. Bashashati, 2023, Gynecologic Oncology.

Hereditary coproporphyria: Exon screening by heteroduplex analysis detects three novel mutations in the coproporphyrinogen oxidase gene

J. Senz, X. Zhang, W. E. Schreiber, 1997, Human mutation.

Mutation screening by denaturing gradient gel electrophoresis in North American patients with acute intermittent porphyria.

J. Senz, M. Hørder, W. E. Schreiber, 1998, Clinical chemistry.

Extrauterine high-grade serous carcinomas with bilateral adnexal involvement as the only two disease sites are clonal based on tp53 sequencing results: implications for biology, classification, and staging

J. Senz, M. Anglesio, C. Gilks, 2017, Modern Pathology.

Subclonal p53 immunostaining in the diagnosis of endometrial carcinoma molecular subtype

S. Leung, M. Köbel, J. Senz, 2023, Histopathology.

Germline E-cadherin mutations in hereditary diffuse gastric cancer: assessment of 42 new families and review of genetic screening criteria

W. Foulkes, Y. Butterfield, C. Caldas, 2004, Journal of Medical Genetics.

ARID1A mutations in endometriosis-associated ovarian carcinomas.

Richard A. Moore, Allen D. Delaney, S. Fereday, 2010, The New England journal of medicine.

Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer

Richard A. Moore, Allen W. Zhang, A. Bashashati, 2016, Nature Genetics.

Hereditary Diffuse Gastric Cancer Syndrome: CDH1 Mutations and Beyond.

B. Fernandez, A. Talhouk, C. Caldas, 2015, JAMA oncology.

Cell State of Origin Impacts Development of Distinct Endometriosis-Related Ovarian Carcinoma Histotypes

J. Senz, M. Anglesio, Karolin Heinze, 2023, Cancer research.

Bi-allelic Dicer1 mutations in the gynecologic tract of mice drive lineage-specific development of DICER1 syndrome-associated cancer.

D. Huntsman, J. Senz, Winnie Yang, 2023, Cancer Research.

Recurrent DICER1 hotspot mutations in endometrial tumours and their impact on microRNA biogenesis

Jamie Rosner, D. Huntsman, J. Senz, 2015, Journal of Pathology.