P. Thanos

发表

Whole-brain circuit dissection in free-moving animals reveals cell-specific mesocorticolimbic networks.

N. Volkow, M. Michaelides, S. A. Anderson, 2013, The Journal of clinical investigation.

Segmentation of rodent brains from MRI based on a novel statistical structure prediction method

George J. Pappas, Dimitris N. Metaxas, Sukmoon Chang, 2009, 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro.

The effects of cocaine on regional brain glucose metabolism is attenuated in dopamine transporter knockout mice

N. Volkow, M. Michaelides, P. Thanos, 2008, Synapse.

Evidence of gender differences in the ability to inhibit brain activation elicited by food stimulation

N. Volkow, K. Pradhan, P. Thanos, 2009, Proceedings of the National Academy of Sciences.

Nora D Volkow, Joanna S Fowler, N. Volkow, 2004, Journal of addictive diseases.

Imaging of Brain Dopamine Pathways: Implications for Understanding Obesity

N. Volkow, P. Thanos, Gene-Jack Wang, 2009, Journal of addiction medicine.

Inverse Association Between BMI and Prefrontal Metabolic Activity in Healthy Adults

Rita Z. Goldstein, N. Volkow, N. Alia-Klein, 2009, Obesity.

Mapping Brain Metabolic Connectivity in Awake Rats with μPET and Optogenetic Stimulation

N. Volkow, M. Michaelides, E. Nestler, 2013, The Journal of Neuroscience.

Evidence That Sleep Deprivation Downregulates Dopamine D2R in Ventral Striatum in the Human Brain

N. Volkow, D. Tomasi, P. Thanos, 2012, The Journal of Neuroscience.

Dopamine homeostasis: brain functional connectivity in reward deficiency syndrome.

K. Blum, M. Febo, P. Thanos, 2017, Frontiers in bioscience.

Gastric stimulation in obese subjects activates the hippocampus and other regions involved in brain reward circuitry

N. Volkow, D. Tomasi, P. Thanos, 2006, Proceedings of the National Academy of Sciences.

Analysis of Evidence for the Combination of Pro-dopamine Regulator (KB220PAM) and Naltrexone to Prevent Opioid Use Disorder Relapse.

K. Blum, M. Febo, P. Thanos, 2018, EC psychology and psychiatry.

Enhanced functional connectivity and volume between cognitive and reward centers of naïve rodent brain produced by pro-dopaminergic agent KB220Z

K. Blum, M. Febo, P. Kulkarni, 2017, PloS one.

The role of central dopamine D3 receptors in drug addiction: a review of pharmacological evidence

J. Hagan, P. Thanos, Z. Xi, 2005, Brain Research Reviews.

The Food and Drug Addiction Epidemic: Targeting Dopamine Homeostasis.

K. Blum, M. Febo, P. Thanos, 2017, Current pharmaceutical design.

Unpredictable chronic mild stress differentially impacts resting brain glucose metabolism in fatty acid-binding protein 7 deficient mice

P. Thanos, Yoshiteru Kagawa, Y. Owada, 2022, Psychiatry Research: Neuroimaging.

Positron Emission Tomographic Evidence of Similarity Between Obesity and Drug Addiction

N. Volkow, P. Thanos, Gene-Jack Wang, 2003 .

Translational neuroimaging in drug addiction and obesity.

N. Volkow, M. Michaelides, P. Thanos, 2012, ILAR journal.

Hypothesizing Nutrigenomic-Based Precision Anti-Obesity Treatment and Prophylaxis: Should We Be Targeting Sarcopenia Induced Brain Dysfunction?

William B. Downs, K. Blum, P. Thanos, 2021, International journal of environmental research and public health.

Oral haloperidol or olanzapine intake produces distinct and region-specific increase in cannabinoid receptor levels that is prevented by high fat diet

P. Thanos, F. Delis, K. Leonard, 2017, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

A Novel Precision Approach to Overcome the “Addiction Pandemic” by Incorporating Genetic Addiction Risk Severity (GARS) and Dopamine Homeostasis Restoration

K. Blum, P. Thanos, R. Badgaiyan, 2021, Journal of personalized medicine.

Environmental enrichment sex-dependently rescues memory impairment in FABP5 KO mice not mediated by brain-derived neurotrophic factor

P. Thanos, Yoshiteru Kagawa, Y. Owada, 2022, Behavioural Brain Research.

Roux-en-Y gastric bypass in rat reduces mu-opioid receptor levels in brain regions associated with stress and energy regulation

P. Thanos, A. Hajnal, John Hamilton, 2019, PloS one.

Genetic addiction risk score (GARS) ™, a predictor of vulnerability to opioid dependence.

Thomas J. H. Chen, K. Blum, M. Febo, 2018, Frontiers in bioscience.

Roux-en-Y Gastric Bypass Alters Brain Activity in Regions that Underlie Reward and Taste Perception

N. Volkow, M. Michaelides, P. Thanos, 2015, PloS one.

Examination of the Addictive and Behavioral Properties of Fatty Acid-Binding Protein Inhibitor SBFI26

S. Haj-Dahmane, D. Deutsch, P. Thanos, 2016, Front. Psychiatry.

Ethanol self-administration and ethanol conditioned place preference are reduced in mice lacking cannabinoid CB1 receptors

N. Volkow, P. Thanos, A. Gifford, 2005, Behavioural Brain Research.

MicroPET investigation of chronic long-term neurotoxicity from heavy ion irradiation

M. Michaelides, P. Thanos, S. Gatley, 2006, The AAPS Journal.

Understanding the Scientific Basis of Post-traumatic Stress Disorder (PTSD): Precision Behavioral Management Overrides Stigmatization

K. Blum, P. Thanos, M. Oscar-Berman, 2019, Molecular Neurobiology.

Introducing Precision Addiction Management of Reward Deficiency Syndrome, the Construct That Underpins All Addictive Behaviors

K. Blum, P. Thanos, R. Badgaiyan, 2018, Front. Psychiatry.

Global Evidence for the Key Role of the Dopamine D2 Receptor Gene (DRD2) and DRD2 Receptors in Alcoholism

K. Blum, P. Thanos, L. Mitchell, 2017 .

Insurance Companies Fighting the Peer Review Empire without any Validity: the Case for Addiction and Pain Modalities in the face of an American Drug Epidemic.

K. Blum, P. Thanos, R. Badgaiyan, 2018, SEJ surgery and pain.

Ethanol Induced Brain Lipid Changes in Mice Assessed by Mass Spectrometry.

J. A. Schultz, N. Volkow, P. Thanos, 2016, ACS chemical neuroscience.

Persistent Dopamine Functions of Neurons Derived from Embryonic Stem Cells in a Rodent Model of Parkinson Disease

Michael V. Green, R. McKay, I. Velasco, 2007, Stem cells.

Chronic aerobic exercise: Autoradiographic assessment of GABA(a) and mu-opioid receptor binding in adult rats

P. Thanos, John Hamilton, N. Rahman, 2020, Pharmacology Biochemistry and Behavior.

Reward Deficiency Syndrome (RDS) Surprisingly Is Evolutionary and Found Everywhere: Is It “Blowin’ in the Wind”?

K. Blum, P. Thanos, J. Cadet, 2022, Journal of personalized medicine.

Bromocriptine increased operant responding for high fat food but decreased chow intake in both obesity-prone and resistant rats

N. Volkow, M. Michaelides, P. Thanos, 2011, Behavioural Brain Research.

Chronic Methamphetamine Effects on Brain Structure and Function in Rats

N. Volkow, M. Ananth, P. Thanos, 2016, PloS one.

Brief and extended abstinence from chronic oral methylphenidate treatment produces reversible behavioral and physiological effects.

P. Thanos, M. Hadjiargyrou, Leanna Kalinowski, 2019, Developmental psychobiology.

Dopamine D4 receptors modulate brain metabolic activity in the prefrontal cortex and cerebellum at rest and in response to methylphenidate

N. Volkow, M. Michaelides, D. Grandy, 2010, The European journal of neuroscience.

Daily treadmill exercise attenuates cocaine cue-induced reinstatement and cocaine induced locomotor response but increases cocaine-primed reinstatement

N. Volkow, P. Thanos, Gene-Jack Wang, 2013, Behavioural Brain Research.

A Systems Biological Approach Coupling Reward Gene Polymorphisms and aNutraceutical (KB220Z) Pro-Dopamine Regulator (PDR) as Putative“Standard of Care” to Treat Reward Deficiency Syndrome (RDS): EmergingEvidence - Based Scientific Induction of “Dopamine Homeostasis”

K. Blum, P. Thanos, R. Badgaiyan, 2020 .

Brain Mapping the Effects of Chronic Aerobic Exercise in the Rat Brain Using FDG PET

K. Blum, P. Thanos, John Hamilton, 2022, Journal of Personalized Medicine.

Limbic activation to novel versus familiar food cues predicts food preference and alcohol intake

N. Volkow, M. Michaelides, P. Thanos, 2013, Brain Research.

Hypodopaminergia and "Precision Behavioral Management" (PBM): It is a Generational Family Affair.

William B. Downs, K. Blum, P. Thanos, 2019, Current pharmaceutical biotechnology.

The Benefits of Genetic Addiction Risk Score (GARS™) Testing in Substance Use Disorder (SUD).

K. Blum, D. Barh, P. Thanos, 2018, International journal of genomics and data mining.

Substance use disorder a bio-directional subset of reward deficiency syndrome.

K. Blum, P. Thanos, T. Archer, 2017, Frontiers in bioscience.

Knockout of p11 attenuates the acquisition and reinstatement of cocaine conditioned place preference in male but not in female mice

P. Greengard, N. Volkow, P. Thanos, 2016, Synapse.

Chronic oral methylphenidate treatment increases microglial activation in rats

David E. Komatsu, P. Thanos, F. Delis, 2018, Journal of Neural Transmission.

The selective dopamine D3 receptor antagonist SB-277011-A attenuates ethanol consumption in ethanol preferring (P) and non-preferring (NP) rats

N. Volkow, M. Michaelides, P. Thanos, 2005, Pharmacology Biochemistry and Behavior.

Prenatal Effects of Nicotine on Obesity Risks: A Narrative Review

K. Blum, P. Thanos, Nicole Roeder, 2022, International journal of environmental research and public health.

Regulation of ethanol intake under chronic mild stress: roles of dopamine receptors and transporters

N. Volkow, D. Grandy, P. Thanos, 2015, Front. Behav. Neurosci..

Why haven't we solved the addiction crisis?

K. Blum, D. Barh, P. Thanos, 2022, Journal of the Neurological Sciences.

genotype predicts longevity in mouse and human.

N. Volkow, D. Grandy, M. Rubinstein, 2012 .

Statistical Validation of Risk Alleles in Genetic Addiction Risk Severity (GARS) Test: Early Identification of Risk for Alcohol Use Disorder (AUD) in 74,566 Case–Control Subjects

K. Blum, P. Thanos, R. Badgaiyan, 2022, Journal of personalized medicine.

Abstinence following intermittent methylphenidate exposure dose‐dependently modifies brain glucose metabolism in the rat brain

P. Thanos, M. Hadjiargyrou, M. Sajjad, 2022, Synapse.

Neurogenetic and Epigenetic Aspects of Cannabinoids

K. Blum, P. Thanos, R. Badgaiyan, 2022, Epigenomes.

Researching Mitigation of Alcohol Binge Drinking in Polydrug Abuse: KCNK13 and RASGRF2 Gene(s) Risk Polymorphisms Coupled with Genetic Addiction Risk Severity (GARS) Guiding Precision Pro-Dopamine Regulation

K. Blum, M. Febo, P. Thanos, 2022, Journal of personalized medicine.

Fatty acid-binding proteins 5 and 7 gene deletion increases sucrose consumption and diminishes forced swim immobility time

S. Haj-Dahmane, D. Deutsch, P. Thanos, 2018, Behavioural pharmacology.

Bariatric surgery: Potential post-operative heightened sensitivity to substances or behaviors

P. Thanos, R. Badgaiyan, M. Gold, 2021, Journal of systems and integrative neuroscience.

Exploration of Epigenetic State Hyperdopaminergia (Surfeit) and Genetic Trait Hypodopaminergia (Deficit) During Adolescent Brain Development.

K. Blum, P. Thanos, T. Simpatico, 2021, Current psychopharmacology.

Genetic and pharmacological manipulations of the CB1 receptor alter ethanol preference and dependence in ethanol preferring and nonpreferring mice

N. Volkow, P. Thanos, T. Cooper, 2008, Synapse.

High Fat Diet Increases [3H] Flunitrazepam Binding in the Mouse Brain that is Dependent on the Expression of the Dopamine D2 Gene

P. Thanos, T. Quattrin, John Hamilton, 2022, Neurochemical Research.

Low doses of alcohol substantially decrease glucose metabolism in the human brain

Nora D. Volkow, Gene-Jack Wang, Joanna S. Fowler, 2006, NeuroImage.

Alcohol binge drinking decreases brain glucose metabolism and functional connectivity in adolescent rats

P. Thanos, M. Sajjad, John Hamilton, 2022, Metabolic Brain Disease.

A non-invasive method for detecting the metabolic stress response in rodents: characterization and disruption of the circadian corticosterone rhythm.

N. Volkow, M. Michaelides, P. Thanos, 2009, Physiological research.

Hypothesizing That Pediatric Autoimmune Neuropsychiatric Associated Streptococcal (PANDAS) Causes Rapid Onset of Reward Deficiency Syndrome (RDS) Behaviors and May Require Induction of “Dopamine Homeostasis”

K. Blum, P. Thanos, D. Baron, 2022, Open journal of immunology.

Calorie restriction, but not Roux‐en‐Y gastric bypass surgery, increases [3H] PK11195 binding in a rat model of obesity

P. Thanos, T. Quattrin, A. Hajnal, 2022, Synapse.

Chronic oral olanzapine treatment but not haloperidol decreases [3H] MK-801 binding in the rat brain Independent of dietary conditions

P. Thanos, John Hamilton, Brittany S. Richardson, 2022, Neuroscience Letters.

Pharmacological Inhibition of Brain Fatty Acid Binding Protein Reduces Ethanol Consumption in Mice

S. Haj-Dahmane, D. Deutsch, K. Blum, 2017, Journal of reward deficiency syndrome and addiction science.

Mouse Social Interaction Test (MoST): a quantitative computer automated analysis of behavior

Dimitris N. Metaxas, P. Thanos, Joseph R. O’Rourke, 2015, Journal of neural transmission.

Should Reward Deficiency Syndrome (RDS) Be Considered an Umbrella Disorder for Mental Illness and Associated Genetic and Epigenetic Induced Dysregulation of Brain Reward Circuitry?

K. Blum, D. Barh, P. Thanos, 2022, Journal of personalized medicine.

Exercise Modulates Brain Glucose Utilization Response to Acute Cocaine

K. Blum, P. Thanos, R. Badgaiyan, 2022, Journal of personalized medicine.

Genetic Addiction Risk Severity Assessment Identifies Polymorphic Reward Genes as Antecedents to Reward Deficiency Syndrome (RDS) Hypodopaminergia’s Effect on Addictive and Non-Addictive Behaviors in a Nuclear Family

K. Blum, P. Thanos, R. Badgaiyan, 2022, Journal of personalized medicine.

Theorizing the Role of Dopaminergic Polymorphic Risk Alleles with Intermittent Explosive Disorder (IED), Violent/Aggressive Behavior and Addiction: Justification of Genetic Addiction Risk Severity (GARS) Testing

K. Blum, P. Thanos, R. Badgaiyan, 2022, Journal of personalized medicine.

Precision Behavioral Management (PBM): A Novel Genetically Guided Therapy to Combat Reward Deficiency Syndrome (RDS) Relevant to the Opiate Crisis

K. Blum, P. Thanos, T. Simpatico, 2020 .

Low dopamine striatal D2 receptors are associated with prefrontal metabolism in obese subjects: Possible contributing factors

Yu-Shin Ding, Nora D. Volkow, Panayotis K. Thanos, 2008, NeuroImage.

3D Segmentation of Rodent Brain Structures Using Hierarchical Shape Priors and Deformable Models

Junzhou Huang, Dimitris N. Metaxas, Shaoting Zhang, 2011, MICCAI.

3d segmentation of rodent brain structures using active volume model with shape priors; conference paper

Junzhou Huang, Dimitris N. Metaxas, Shaoting Zhang, 2011, ISBI 2011.

Obesity-resistant S5B rats showed greater cocaine conditioned place preference than the obesity-prone OM rats

N. Volkow, M. Michaelides, P. Thanos, 2010, Physiology & Behavior.

Overexpression of dopamine D2 receptors reduces alcohol self‐administration

N. Volkow, D. Ingram, P. Thanos, 2001, Journal of neurochemistry.

Altered cerebellar organization and function in monoamine oxidase A hypomorphic mice

Ryan D. Darling, N. Volkow, P. Thanos, 2012, Neuropharmacology.

Effects of Δ9-Tetrahydrocannibinol (THC) on Obesity at Different Stages of Life: A Literature Review

P. Thanos, Samantha Penman, Nathan Fearby, 2022, International journal of environmental research and public health.

Automated Method for Small-Animal PET Image Registration with Intrinsic Validation

Manuel Desco, Juan José Vaquero, Nora D. Volkow, 2009, Molecular Imaging and Biology.

DRD2 gene transfer into the nucleus accumbens core of the alcohol preferring and nonpreferring rats attenuates alcohol drinking.

N. Volkow, D. Ingram, P. Thanos, 2004, Alcoholism, clinical and experimental research.

Fatty-acid–binding protein 5 controls retrograde endocannabinoid signaling at central glutamate synapses

S. Haj-Dahmane, D. Deutsch, P. Thanos, 2018, Proceedings of the National Academy of Sciences.

Fatty acid binding protein deletion prevents stress‐induced preference for cocaine and dampens stress‐induced corticosterone levels

S. Haj-Dahmane, D. Deutsch, P. Thanos, 2018, Synapse.

Fluoxetine Potentiates Oral Methylphenidate-Induced Gene Regulation in the Rat Striatum

H. Steiner, P. Thanos, M. Marion, 2021, Molecular Neurobiology.

Roux-en-Y gastric bypass increases GABA-A receptor levels in regions of the rat brain involved in object recognition memory and perceptual acuity

P. Thanos, A. Hajnal, John Hamilton, 2020, Physiology & Behavior.

Chronic oral methylphenidate treatment reversibly increases striatal dopamine transporter and dopamine type 1 receptor binding in rats

David E. Komatsu, M. Ananth, P. Thanos, 2017, Journal of Neural Transmission.

Future Newborns with Opioid-Induced Neonatal Abstinence Syndrome (NAS) Could Be Assessed with the Genetic Addiction Risk Severity (GARS) Test and Potentially Treated Using Precision Amino-Acid Enkephalinase Inhibition Therapy (KB220) as a Frontline Modality Instead of Potent Opioids

K. Blum, D. Barh, P. Thanos, 2022, Journal of personalized medicine.

Reproducibility of 11C-raclopride binding in the rat brain measured with the microPET R4: effects of scatter correction and tracer specific activity.

Jean Logan, Paul Vaska, Nora D Volkow, 2003, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Clinically Combating Reward Deficiency Syndrome (RDS) with Dopamine Agonist Therapy as a Paradigm Shift: Dopamine for Dinner?

K. Blum, M. Febo, P. Thanos, 2015, Molecular Neurobiology.

Bromocriptine Administration Reduces Hyperphagia and Adiposity and Differentially Affects Dopamine D2 Receptor and Transporter Binding in Leptin-Receptor-Deficient Zucker Rats and Rats with Diet-Induced Obesity

N. Volkow, M. Michaelides, P. Thanos, 2008, Neuroendocrinology.

In vivo comparative imaging of dopamine D2 knockout and wild-type mice with (11)C-raclopride and microPET.

Jing-Huei Lee, Jean Logan, Paul Vaska, 2002, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

The therapeutic potential of exercise for neuropsychiatric diseases: A review

K. Blum, P. Thanos, T. McLaughlin, 2020, Journal of the Neurological Sciences.

High Genetic Addiction Risk Score (GARS) in Chronically Prescribed Severe Chronic Opioid Probands Attending Multi-pain Clinics: an Open Clinical Pilot Trial

K. Blum, P. Thanos, J. Cadet, 2021, Molecular Neurobiology.

Passive Response to Stress in Adolescent Female and Adult Male Mice after Intermittent Nicotine Exposure in Adolescence.

N. Volkow, P. Thanos, F. Delis, 2013, Journal of addiction research & therapy.

Dopamine D2R DNA transfer in dopamine D2 receptor-deficient mice: effects on ethanol drinking.

N. Volkow, D. Grandy, M. Rubinstein, 2005, Life sciences.

Role of dopamine D3 receptors in the addictive properties of ethanol.

P. Thanos, C. Heidbreder, E. Gardner, 2004, Drugs of today.

Suboptimal maternal diets alter mu opioid receptor and dopamine type 1 receptor binding but exert no effect on dopamine transporters in the offspring brain

M. Ananth, P. Thanos, F. Delis, 2018, International Journal of Developmental Neuroscience.

Examining the role of cannabinoids on osteoporosis: a review

P. Thanos, M. Hadjiargyrou, Samantha Penman, 2022, Archives of Osteoporosis.

Endorphinergic Enhancement Attenuation of Post-traumatic Stress Disorder (PTSD) via Activation of Neuro-immunological Function in the Face of a Viral Pandemic.

K. Blum, P. Thanos, R. Badgaiyan, 2021, Current psychopharmacology.

The effect of dopamine D4 receptor density on novelty seeking, activity, social interaction, and alcohol binge drinking in adult mice

D. Grandy, P. Thanos, Onarae V Rice, 2015, Synapse.

Genetic Addiction Risk and Psychological Profiling Analyses for “Preaddiction” Severity Index

K. Blum, D. Barh, P. Thanos, 2022, Journal of personalized medicine.

Preputial graft in penile curvature correction: preliminary results

P. Thanos, I. Vakalopoulos, D. Radopoulos, 2009, International Journal of Impotence Research.

D2R DNA transfer into the nucleus accumbens attenuates cocaine self‐administration in rats

N. Volkow, M. Michaelides, P. Thanos, 2008, Synapse.

Reverse Pharmacogenetic Modulation of the Nucleus Accumbens Reduces Ethanol Consumption in a Limited Access Paradigm

Gord Fishell, Lucas Sjulson, G. Fishell, 2014, Neuropsychopharmacology.

Combined methylphenidate and fluoxetine treatment in adolescent rats significantly impairs weight gain with minimal effects on skeletal development.

P. Thanos, M. Hadjiargyrou, S. Z. Uddin, 2022, Bone.

Recovery from behavior and developmental effects of chronic oral methylphenidate following an abstinence period

David E. Komatsu, P. Thanos, M. Hadjiargyrou, 2018, Pharmacology Biochemistry and Behavior.

DRD4 Genotype Predicts Longevity in Mouse and Human

N. Volkow, D. Grandy, M. Rubinstein, 2013, The Journal of Neuroscience.

Chronic oral methylphenidate treatment in adolescent rats promotes dose-dependent effects on NMDA receptor binding.

David E. Komatsu, P. Thanos, F. Delis, 2020, Life sciences.

Weekday-only chronic oral methylphenidate self-administration in male rats: Reversibility of the behavioral and physiological effects

David E. Komatsu, P. Thanos, M. Hadjiargyrou, 2019, Behavioural Brain Research.

Methylphenidate regulation of osteoclasts in a dose- and sex-dependent manner adversely affects skeletal mechanical integrity

P. Thanos, M. Hadjiargyrou, L. Robison, 2018, Scientific Reports.

Sex Differences in the Physiological and Behavioral Effects of Chronic Oral Methylphenidate Treatment in Rats

David E. Komatsu, P. Thanos, M. Hadjiargyrou, 2017, Front. Behav. Neurosci..

A pharmacokinetic model of oral methylphenidate in the rat and effects on behavior

David E. Komatsu, N. Volkow, P. Thanos, 2015, Pharmacology Biochemistry and Behavior.

Chronic exposure to methylphenidate impairs appendicular bone quality in young rats.

Haden A. Janda, David E. Komatsu, J. Swanson, 2012, Bone.

Gastric distention activates satiety circuitry in the human brain

Nora D. Volkow, Panayotis K. Thanos, Gene-Jack Wang, 2008, NeuroImage.

Chronic treatment and abstinence from methylphenidate exposure dose-dependently changes glucose metabolism in the rat brain

K. Blum, P. Thanos, F. Delis, 2022, Brain Research.

Dopaminergic and other genes related to reward induced overeating, Bulimia, Anorexia Nervosa, and Binge eating

P. Thanos, Gene-Jack Wang, D. Baron, 2021, Expert Review of Precision Medicine and Drug Development.

Food restriction markedly increases dopamine D2 receptor (D2R) in a rat model of obesity as assessed with in‐vivo μPET imaging ([11C] raclopride) and in‐vitro ([3H] spiperone) autoradiography

N. Volkow, M. Michaelides, P. Thanos, 2008, Synapse.

Upregulation of cannabinoid type 1 receptors in dopamine D2 receptor knockout mice is reversed by chronic forced ethanol consumption.

N. Volkow, M. Michaelides, D. Grandy, 2011, Alcoholism, clinical and experimental research.

Leptin receptor deficiency is associated with upregulation of cannabinoid 1 receptors in limbic brain regions

N. Volkow, M. Michaelides, P. Thanos, 2008, Synapse.

Addiction by Any Other Name is Still Addiction: Embracing Molecular Neurogenetic/Epigenetic Basis of Reward Deficiency

William B. Downs, K. Blum, P. Thanos, 2020, Journal of addiction science.

Roux‐en‐Y gastric bypass surgery normalizes dopamine D1, D2, and DAT levels

P. Thanos, A. Hajnal, John Hamilton, 2018, Synapse.

Hypothesizing Las Vegas and Sutherland Springs Mass Shooters Suffer from Reward Deficiency Syndrome: “Born Bad”

D. Mash, K. Blum, P. Thanos, 2017, Journal of reward deficiency syndrome and addiction science.

Dopamine D2 gene expression interacts with environmental enrichment to impact lifespan and behavior

N. Volkow, K. Blum, M. Febo, 2016, Oncotarget.

Dopamine and glucose, obesity, and reward deficiency syndrome

Kenneth Blum, Mark S. Gold, Panayotis K. Thanos, 2014, Front. Psychol..

Dopamine D4 receptor gene expression plays important role in extinction and reinstatement of cocaine-seeking behavior in mice

M. Ananth, P. Thanos, John Hamilton, 2019, Behavioural Brain Research.

Dopamine D4 receptor (D4R) deletion in mice does not affect operant responding for food or cocaine

N. Volkow, M. Michaelides, D. Grandy, 2010, Behavioural Brain Research.

The functional networks of a novel environment: Neural activity mapping in awake unrestrained rats using positron emission tomography

M. Ananth, P. Thanos, M. McGregor, 2020, Brain and behavior.

Chronic aerobic exercise: Lack of effect on brain CB1 receptor levels in adult rats.

P. Thanos, L. Robison, John Hamilton, 2019, Life sciences.

Fatty Acid-Binding Protein 5 Gene Deletion Enhances Nicotine-Conditioned Place Preference: Illuminating the Putative Gateway Mechanisms

K. Blum, P. Thanos, M. Gold, 2023, Future pharmacology.

Chronic forced exercise inhibits stress-induced reinstatement of cocaine conditioned place preference

P. Thanos, L. Robison, Luke Alessi, 2018, Behavioural Brain Research.

Chronic forced exercise during adolescence decreases cocaine conditioned place preference in Lewis rats

N. Volkow, P. Thanos, Gene-Jack Wang, 2010, Behavioural Brain Research.

N. Volkow, M. Michaelides, P. Thanos, 2012, International review of psychiatry.

Offering a putative neurobiological “dopamine homeostatic” solution to overcome the perils of the reward deficiency syndrome pandemic: emergence of “precision behavioral management”

K. Blum, P. Thanos, R. Badgaiyan, 2022, Annals of translational medicine.

Understanding that Addiction Is a Brain Disorder Offers Help and Hope

K. Blum, P. Thanos, R. Badgaiyan, 2022, Health.

Positive Clinical Outcomes for Severe Reported Pain Using Robust Non-Addictive Home Electrotherapy—A Case-Series

K. Blum, D. Barh, P. Thanos, 2023, Journal of Personalized Medicine.

Prenatal tobacco and cannabis co‐exposure and offspring obesity development from birth to mid‐childhood

Kai Ling Kong, P. Thanos, M. Huestis, 2023, Pediatric obesity.

Dissociation between spontaneously hypertensive (SHR) and Wistar–Kyoto (WKY) rats in baseline performance and methylphenidate response on measures of attention, impulsivity and hyperactivity in a Visual Stimulus Position Discrimination Task

J. Swanson, N. Volkow, M. Michaelides, 2010, Pharmacology Biochemistry and Behavior.

The effects of two highly selective dopamine D3 receptor antagonists (SB-277011A and NGB-2904) on food self-administration in a rodent model of obesity

N. Volkow, M. Michaelides, P. Thanos, 2008, Pharmacology Biochemistry and Behavior.

Gender Differences in Brain Activation by Food Stimulation

N. Volkow, P. Thanos, Gene-Jack Wang, 2011 .

Alcohol Reward Is Increased after Roux-en-Y Gastric Bypass in Dietary Obese Rats with Differential Effects following Ghrelin Antagonism

N. Volkow, P. Thanos, A. Hajnal, 2012, PloS one.

Chronic Ethanol Consumption Profoundly Alters Regional Brain Ceramide and Sphingomyelin Content in Rodents

N. Volkow, P. Thanos, A. Woods, 2014, ACS chemical neuroscience.

Exercise Reduces Dopamine D1R and Increases D2R in Rats: Implications for Addiction

P. Thanos, L. Robison, John Hamilton, 2018, Medicine and science in sports and exercise.

Chronic co-administration of nicotine and methamphetamine causes differential expression of immediate early genes in the dorsal striatum and nucleus accumbens of Rats

P. Thanos, J. Cadet, N. Volkow, 2013, Neuroscience.

Effects of chronic oral methylphenidate on cocaine self-administration and striatal dopamine D2 receptors in rodents

N. Volkow, M. Michaelides, P. Thanos, 2007, Pharmacology Biochemistry and Behavior.

D‐cycloserine facilitates extinction of cocaine self‐administration in rats

N. Volkow, P. Thanos, Gene-Jack Wang, 2011, Synapse.

d-Cycloserine accelerates the extinction of cocaine-induced conditioned place preference in C57bL/c mice

N. Volkow, P. Thanos, Gene-Jack Wang, 2009, Behavioural Brain Research.

Obese rats with deficient leptin signaling exhibit heightened sensitivity to olfactory food cues

N. Volkow, M. Michaelides, P. Thanos, 2013, Synapse.

Brain kinetics of methylphenidate (Ritalin) enantiomers after oral administration

N. Volkow, P. Thanos, J. Fowler, 2004, Synapse.

“Preaddiction” construct and reward deficiency syndrome: genetic link via dopaminergic dysregulation

K. Blum, P. Thanos, R. Badgaiyan, 2022, Annals of translational medicine.

Decreased brain dopaminergic responses in active cocaine dependent subjects

N. Volkow, K. Pradhan, P. Thanos, 2010 .

A high-fat diet, but not haloperidol or olanzapine administration, increases activated microglial expression in the rat brain

P. Thanos, John Hamilton, Marsha Maredia, 2021, Neuroscience Letters.

Behavioral, Neurochemical and Developmental Effects of Chronic Oral Methylphenidate: A Review

K. Blum, P. Thanos, R. Badgaiyan, 2023, Journal of personalized medicine.

Effects of chronic methamphetamine on psychomotor and cognitive functions and dopamine signaling in the brain

N. Volkow, P. Thanos, F. Delis, 2017, Behavioural Brain Research.

D‐cycloserine facilitates extinction of cocaine self‐administration in c57 mice

N. Volkow, M. Michaelides, M. Ananth, 2011, Synapse.

Chronic mild stress increases alcohol intake in mice with low dopamine D2 receptor levels.

N. Volkow, D. Grandy, P. Thanos, 2013, Behavioral neuroscience.

Loss of dopamine D2 receptors induces atrophy in the temporal and parietal cortices and the caudal thalamus of ethanol-consuming mice.

N. Volkow, D. Grandy, P. Thanos, 2012, Alcoholism, clinical and experimental research.

Positron Emission Tomography As a Tool for Studying Alcohol Abuse

N. Volkow, P. Thanos, Gene-Jack Wang, 2008, Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism.

Striatal Rgs4 regulates feeding and susceptibility to diet-induced obesity

Randall J. Ellis, N. Volkow, G. Bray, 2018, Molecular Psychiatry.

The long-term interaction of diet and dopamine D2 gene expression on brain microglial activation

K. Blum, P. Thanos, John Hamilton, 2021, Psychiatry Research: Neuroimaging.

Leptin increases striatal dopamine D2 receptor binding in leptin‐deficient obese (ob/ob) mice

N. Volkow, M. Michaelides, P. Thanos, 2010, Synapse.

Roux-en-Y Gastric Bypass Increases Intravenous Ethanol Self-Administration in Dietary Obese Rats

N. Volkow, P. Thanos, A. Hajnal, 2013, PloS one.

Gastric Bypass Increases Ethanol and Water Consumption in Diet-Induced Obese Rats

N. Volkow, P. Thanos, Gene-Jack Wang, 2012, Obesity Surgery.

Functional Neuroimaging in Obesity

N. Volkow, M. Michaelides, P. Thanos, 2011 .

Correction: Chronic Methamphetamine Effects on Brain Structure and Function in Rats

N. Volkow, M. Ananth, P. Thanos, 2017, PloS one.

PET imaging predicts future body weight and cocaine preference

Nora D. Volkow, Panayotis K. Thanos, Gene-Jack Wang, 2012, NeuroImage.

Fatty acid binding protein deletion suppresses inflammatory pain through endocannabinoid/N-acylethanolamine-dependent mechanisms

P. Thanos, M. Rebecchi, S. Glaser, 2015, Molecular pain.

3D segmentation of rodent brains using deformable models and variational methods

George J. Pappas, Xiaoxu Wang, Dimitris N. Metaxas, 2009, 2009 IEEE Computer Society Conference on Computer Vision and Pattern Recognition Workshops.

Effects of Exercise on Testosterone and Implications of Drug Abuse: A Review

P. Thanos, Nikki Hammond, Brendan Perreault, 2023, Clinical neuropharmacology.

Dopaminylation in Psychostimulant Use Disorder Protects Against Psychostimulant Seeking Behavior by Normalizing Nucleus Accumbens (NAc) Dopamine Expression.

K. Blum, P. Thanos, J. Cadet, 2021, Current psychopharmacology.

Fatty acid-binding protein 5 differentially impacts dopamine signaling independent of sex and environment.

P. Thanos, John Hamilton, Nicole Roeder, 2023, Addiction neuroscience.

Impaired periamygdaloid-cortex prodynorphin is characteristic of opiate addiction and depression.

Michael Michaelides, Nora D Volkow, Parisa Zarnegar, 2013, The Journal of clinical investigation.

The First Exploratory Personalized Medicine Approach to Improve Bariatric Surgery Outcomes Utilizing Psychosocial and Genetic Risk Assessments: Encouraging Clinical Research

Aaron B. Hoffman, K. Blum, P. Thanos, 2023, Journal of personalized medicine.

Insulin-like growth factor-I promotes nerve regeneration through a nerve graft in an experimental model of facial paralysis.

P. Thanos, J. Terzis, D. Tiangco, 1999, Restorative neurology and neuroscience.

Notes on “Roux en Y Gastric Bypass Increases Ethanol Intake in the Rat” by Davis et al.

N. Volkow, P. Thanos, A. Hajnal, 2013, Obesity Surgery.

Regional brain metabolism during alcohol intoxication.

J S Fowler, N. Volkow, P. Thanos, 2000, Alcoholism, clinical and experimental research.

Are vascular disorders a common cause of erectile dysfunction in non hypogonadal, non neuropsychiatric patients?

P. Thanos, I. Vakalopoulos, G. Gkotsos, 2011, Hippokratia.

Ultrastructure and Cellular Biology of Nerve Regeneration

P. Thanos, J. Terzis, P. Thanos, 1998, Journal of reconstructive microsurgery.

Decreased dopamine activity predicts relapse in methamphetamine abusers

N. Volkow, N. Alia-Klein, D. Tomasi, 2011, Molecular Psychiatry.

Caffeine increases striatal dopamine D2/D3 receptor availability in the human brain

N. Volkow, D. Tomasi, P. Thanos, 2015, Translational Psychiatry.

Evidence for the DRD2 Gene as a Determinant of Reward Deficiency Syndrome (RDS)

K. Blum, P. Thanos, M. Makale, 2023, Clinical and experimental psychology.

Preliminary Observations of Personalized Repetitive Magnetic Stimulation (PrTMS) Guided by EEG Spectra for Concussion

P. Thanos, D. Baron, Catherine A. Dennen, 2023, Brain sciences.

Metheamphetamine for Children: Are We Over or Under Dosing?

K. Blum, P. Thanos, R. Badgaiyan, 2023, Journal of addiction psychiatry.

Methylphenidate regulation of osteoclasts in a dose- and sex-dependent manner adversely affects skeletal mechanical integrity

P. Thanos, M. Hadjiargyrou, L. Robison, 2018, Scientific Reports.

Invited Expert Opinion- Bioinformatic and Limitation Directives to Help Adopt Genetic Addiction Risk Screening and Identify Preaddictive Reward Dysregulation: Required Analytic Evidence to Induce Dopamine Homeostatsis

P. Thanos, R. Badgaiyan, D. Baron, 2023, Medical research archives.

Genetic Correlates as a Predictor of Bariatric Surgery Outcomes after 1 Year

P. Thanos, Abrianna Mihalkovic, Colin Hanna, 2023, Biomedicines.

Cocaine abusers show a blunted response to alcohol intoxication in limbic brain regions.

J S Fowler, N. Volkow, P. Thanos, 2000, Life sciences.

The role of central dopamine D3 receptors in drug addiction: a review of pharmacological evidence

J. Hagan, P. Thanos, Z. Xi, 2005, Brain Research Reviews.

Chronic co-administration of nicotine and methamphetamine causes differential expression of immediate early genes in the dorsal striatum and nucleus accumbens of Rats

P. Thanos, R. Kim, B. Ladenheim, 2013, Neuroscience.

The effects of two highly selective dopamine D3 receptor antagonists (SB-277011A and NGB-2904) on food self-administration in a rodent model of obesity

N. Volkow, M. Michaelides, P. Thanos, 2008, Pharmacology Biochemistry and Behavior.

Conditioned place preference and locomotor activity in response to methylphenidate, amphetamine and cocaine in mice lacking dopamine D4 receptors

N. Volkow, D. Grandy, P. Thanos, 2010, Journal of psychopharmacology.

Differences in response to food stimuli in a rat model of obesity: in-vivo assessment of brain glucose metabolism

N. Volkow, M. Michaelides, P. Thanos, 2008, International Journal of Obesity.

Chronic oral methylphenidate plus fluoxetine treatment in adolescent rats increases cocaine self-administration

H. Steiner, P. Thanos, M. Hadjiargyrou, 2023, Addiction neuroscience.

D‐cycloserine facilitates extinction of cocaine self‐administration in c57 mice

N. Volkow, M. Michaelides, M. Ananth, 2011, Synapse.

A novel learning based segmentation method for rodent brain structures using MRI

Qingshan Liu, George J. Pappas, Dimitris N. Metaxas, 2008, 2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro.

Exercise Modifies the Brain Metabolic Response to Chronic Cocaine Exposure Inhibiting the Stria Terminalis

P. Thanos, Rutao Yao, Colin Hanna, 2023, Brain sciences.

Chronic Methylphenidate Effects on Brain Gene Expression: An Exploratory Review

P. Thanos, Mark S. Gold, Kenneth Blum, 2024, Psychology research and behavior management.

Vaporized Δ-9THC in utero results in reduced birthweight, increased locomotion, and altered wake-cycle activity dependent on dose, sex, and diet in the offspring.

P. Thanos, Brittany J. Richardson, Samantha L Penman, 2024, Life sciences.

Chronic Δ9-tetrahydrocannabinol treatment has dose-dependent effects on open field exploratory behavior and [3H] SR141716A receptor binding in the rat brain.

P. Thanos, L. Robison, John Hamilton, 2023, Life sciences.

Vaporized Delta-9-tetrahydrocannabinol Inhalation in Female Sprague Dawley Rats: A Pharmacokinetic and Behavioral Assessment.

P. Thanos, Nikki Hammond, Abhisheak Sharma, 2023, Current pharmaceutical design.

Mapping Brain Metabolic Connectivity in Awake Rats with μPET and Optogenetic Stimulation

N. Volkow, M. Michaelides, E. Nestler, 2013, The Journal of Neuroscience.

Chronic oral olanzapine treatment but not haloperidol decreases [3H] MK-801 binding in the rat brain Independent of dietary conditions

P. Thanos, John Hamilton, Brittany S. Richardson, 2022, Neuroscience Letters.

Pharmacological Inhibition of Brain Fatty Acid Binding Protein Reduces Ethanol Consumption in Mice

S. Haj-Dahmane, D. Deutsch, K. Blum, 2017, Journal of reward deficiency syndrome and addiction science.

Addressing cortex dysregulation in youth through brain health check coaching and prophylactic brain development

Margaret A. Madigan, P. Thanos, R. Badgaiyan, 2024, INNOSC theranostics & pharmacological sciences.

3D segmentation of rodent brain structures using Active Volume Model with shape priors

Dimitris N. Metaxas, N. Volkow, Xiaolei Huang, 2011, 2011 IEEE International Symposium on Biomedical Imaging: From Nano to Macro.

Obesity-resistant S5B rats showed greater cocaine conditioned place preference than the obesity-prone OM rats

N. Volkow, M. Michaelides, P. Thanos, 2010, Physiology & Behavior.

N. Volkow, M. Michaelides, P. Thanos, 2008, Neuroendocrinology.

Opioid use disorder: current trends and potential treatments

P. Thanos, Colin Hanna, Mark S. Gold, 2024, Frontiers in public health.

Futuristic Exploration of Addiction Neuroscience in the Genomic Era

P. Thanos, D. Baron, A. Bowirrat, 2023, Psychology research and behavior management.

Neurogenetics and Epigenetics of Loneliness

D. Barh, P. Thanos, R. Badgaiyan, 2023, Psychology research and behavior management.

Dopaminergic dysfunction: Role for genetic & epigenetic testing in the new psychiatry

P. Thanos, R. Badgaiyan, D. Baron, 2023, Journal of the Neurological Sciences.

The Benefits of Genetic Addiction Risk Score (GARS™) Testing in Substance Use Disorder (SUD).

K. Blum, D. Barh, P. Thanos, 2018, International journal of genomics and data mining.

Are We Getting High Cause the Thrill is Gone?

P. Thanos, R. Badgaiyan, D. Baron, 2023, Journal of addiction psychiatry.

Potential Link Between Exercise and N-Methyl-D-Aspartate Glutamate Receptors in Alcohol Use Disorder: Implications for Therapeutic Strategies

P. Thanos, A. Bowirrat, Nikki Hammond, 2024, Psychology research and behavior management.

Exercise Influences the Brain’s Metabolic Response to Chronic Cocaine Exposure in Male Rats

P. Thanos, Rutao Yao, Colin Hanna, 2024, Journal of personalized medicine.

Selenoprotein P in a Rodent Model of Exercise; Theorizing Its Interaction with Brain Reward Dysregulation, Addictive Behavior, and Aging

P. Thanos, R. Badgaiyan, K. Lewandrowski, 2024, Journal of personalized medicine.

Identification of stress-induced epigenetic methylation onto dopamine D2 gene and neurological and behavioral consequences

D. Barh, P. Thanos, R. Badgaiyan, 2024, Gene & protein in disease.

Vaporized nicotine in utero results in reduced birthweight, increased locomotion, and decreased voluntary exercise, dependent on sex and diet in offspring.

P. Thanos, Brittany J. Richardson, Nicole M Roeder, 2024, Psychopharmacology.

Bromocriptine increased operant responding for high fat food but decreased chow intake in both obesity-prone and resistant rats

N. Volkow, M. Michaelides, P. Thanos, 2011, Behavioural Brain Research.

High intensity interval training exercise increases dopamine D2 levels and modulates brain dopamine signaling

P. Thanos, John Hamilton, Nikki Hammond, 2023, Frontiers in public health.

Becker Digital

P. Thanos, R. Badgaiyan, D. Baron, 2022 .

Loss of dopamine D2 receptors induces atrophy in the temporal and parietal cortices and the caudal thalamus of ethanol-consuming mice.

N. Volkow, D. Grandy, P. Thanos, 2012, Alcoholism, clinical and experimental research.

Dopamine Dysregulation in Reward and Autism Spectrum Disorder

P. Thanos, A. Bowirrat, Catherine A. Dennen, 2024, Brain sciences.

d-Cycloserine accelerates the extinction of cocaine-induced conditioned place preference in C57bL/c mice

N. Volkow, P. Thanos, Gene-Jack Wang, 2009, Behavioural Brain Research.

Vaporized Δ9-tetrahydrocannabinol exposure in utero has negative effects on attention in a dose- and sex-dependent manner

P. Thanos, Brittany J. Richardson, Nicole M Roeder, 2024, Pharmacology Biochemistry and Behavior.

Clinical and Preclinical Bariatric Surgery Approaches to Studying Obesity

P. Thanos, T. Quattrin, John Hamilton, 2020 .

A historical perspective on clonidine as an alpha-2A receptor agonist in the treatment of addictive behaviors: Focus on opioid dependence

P. Thanos, R. Badgaiyan, K. Lewandrowski, 2024, INNOSC theranostics & pharmacological sciences.

Summary Document Research on RDS Anti-addiction Modeling: Annotated Bibliography

P. Thanos, R. Badgaiyan, T. McLaughlin, 2024, Journal of addiction psychiatry.

Vilazodone, a Novel SSRI Antidepressant with 5-HT1A Partial Agonist Properties: Diminished Potentiation of Chronic Oral Methylphenidate-Induced Dynorphin Expression in the Striatum in Adolescent Male Rats.

P. Thanos, Rania Ahmed, Michael Hrabak, 2024, Molecular neurobiology.