J. Barrio

Krzysztof P Bobinski, J. Barrio, J. Czernin, 2013, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

1,1-Dicyano-2-[6-(dimethylamino)naphthalen-2-yl]propene (DDNP): A Solvent Polarity and Viscosity Sensitive Fluorophore for Fluorescence Microscopy⊥

J. Barrio, A. Petrič, A. F. Jacobson, 1996 .

Localization of neurofibrillary tangles and beta-amyloid plaques in the brains of living patients with Alzheimer disease.

G. Small, V. Kepe, J. Barrio, 2002, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

The merits of FDDNP-PET imaging in Alzheimer's disease.

G. Small, V. Kepe, J. Barrio, 2011, Journal of Alzheimer's disease : JAD.

Imaging beta-amyloid fibrils in Alzheimer's disease: a critical analysis through simulation of amyloid fibril polymerization.

G. Small, V. Kepe, J. Barrio, 2005, Nuclear medicine and biology.

Kinetics and Modeling of l-6-[18F]Fluoro-DOPA in Human Positron Emission Tomographic Studies

Scott T. Grafton, J. Mazziotta, J. Hoffman, 1991, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Quantifying local cerebral blood flow by N-isopropyl-p-[123I]iodoamphetamine (IMP) tomography.

J. Barrio, D. Kuhl, M. Phelps, 1982, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease.

J. Mazziotta, M. Pericak-Vance, A. Roses, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Towards a Pharmacophore for Amyloid

David Eisenberg, Meytal Landau, Michael R. Sawaya, 2011, PLoS biology.

[F-18]FDDNP microPET imaging correlates with brain Aβ burden in a transgenic rat model of Alzheimer disease: Effects of aging, in vivo blockade, and anti-Aβ antibody treatment

Sung-Cheng Huang, Gary W. Small, Vladimir Kepe, 2011, Neurobiology of Disease.

2-Dialkylamino-6-acylmalononitrile substituted naphthalenes (DDNP analogs): novel diagnostic and therapeutic tools in Alzheimer's disease.

Sung-Cheng Huang, Vladimir Kepe, Nagichettiar Satyamurthy, 2003, Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging.

Effects of a 14-day healthy longevity lifestyle program on cognition and brain function.

G. Small, K. Miller, J. Barrio, 2006, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Regioselective radiofluorodestannylation with [18F]F2 and [18F]CH3COOF: a high yield synthesis of 6-[18F]Fluoro-L-dopa.

N Satyamurthy, J R Barrio, J. Barrio, 1992, International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes.

The Irony of PET Tau Probe Specificity

J. Barrio, Jorge R Barrio, 2018, The Journal of Nuclear Medicine.

Microstructural Imaging of Neurodegenerative Changes

Sung-Cheng Huang, Gary W. Small, Vladimir Kepe, 2009 .

Cerebral amyloid PET imaging in Alzheimer’s disease

C. Jack, V. Kepe, J. Barrio, 2013, Acta Neuropathologica.

Automated VOI Analysis in FDDNP PET Using Structural Warping: Validation through Classification of Alzheimer's Disease Patients

Sung-Cheng Huang, Gary W. Small, Vladimir Kepe, 2012, IEEE Nuclear Science Symposuim & Medical Imaging Conference.

Quantitative Measurement of Local Cerebral Blood Flow in Humans by Positron Computed Tomography and 15O-Water

E. J. Hoffman, R. E. Carson, M. E. Phelps, 1983, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Movement Correction Method for Human Brain PET Images: Application to Quantitative Analysis of Dynamic 18F-FDDNP Scans

Sung-Cheng Huang, Gary W. Small, Koon-Pong Wong, 2010, Journal of Nuclear Medicine.

FLT-PET Imaging of Radiation Responses in Murine Tumors

J. Barrio, S. Huang, Sung-Cheng Huang, 2008, Molecular Imaging and Biology.

Inhibition of adenylate kinase by P1-(lin-benzo-5'-adenosyl)-P4-(5'-adenosyl) tetraphosphate and P1-(lin-benzo-5'-adenosyl)-P5-(5'-adenosyl pentaphosphate.

J. Barrio, N. Leonard, P. Vanderlijn, 1979, Biochemistry.

Species responsible for the fluorescence of 1:N6-ethenoadenosine.

R. D. Spencer, J. Barrio, G. Weber, 1974, European journal of biochemistry.

Chloroacetaldehyde-modified dinucleoside phosphates. Dynamic fluorescence quenching and quenching due to intramolecular complexation.

J. Barrio, N. Leonard, G. Tolman, 1974, Biochemistry.

Fluorescent modification of adenosine-containing coenzymes. Biological activities and spectroscopic properties.

J. Barrio, G. Weber, N. Leonard, 1972, Biochemistry.

Fluorescent adenosine and cytidine derivatives.

J. Barrio, N. Leonard, J. Secrist, 1972, Biochemical and biophysical research communications.

Molecular imaging in biology and pharmacology

J. Barrio, Sung-Cheng Huang, A. Wu, 2020, Biomedical Information Technology.

Kinetics of C-ll labeled palmitate in ischemic myocardium

J. Barrio, H. Schelbert, J. Robinson, 1981 .

The synthesis of 2-[F-18]fluoro-2-deoxy-D-glucose using glycals: a reexamination.

J. Barrio, N. Satyamurthy, G. Bida, 1984, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Nigrostriatal Reduction of Aromatic L‐Amino Acid Decarboxylase Activity in MPTP‐Treated Squirrel Monkeys: In Vivo and In Vitro Investigations

J. Langston, S-C. Huang, J. Barrio, 2000, Journal of neurochemistry.

Cognitive and cerebral metabolic effects of celecoxib versus placebo in people with age-related memory loss: randomized controlled study.

G. Small, K. Miller, S-C. Huang, 2008, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Dynamic positron tomographic imaging with nitrogen-13 glutamate in patients with coronary artery disease: comparison with nitrogen-13 ammonia and fluorine-18 fluorodeoxyglucose imaging.

J. Barrio, S. Huang, H. Schelbert, 1990, Journal of the American College of Cardiology.

18F‐labeled benzamide derivatives: Synthesis of 3,5‐dichloro‐N‐[1‐{2‐[18F]‐fluoroethyl}‐2‐pyrrolidinyl)methyl]‐6‐methoxysalicylamide And derivatives as dopamine D‐2 receptor‐binding radioligands

J. Barrio, N. Satyamurthy, G. Bida, 1989 .

3-(2'-[18F]fluoroethyl)spiperone, a potent dopamine antagonist: synthesis, structural analysis and in-vivo utilization in humans.

J. Mazziotta, J. Barrio, N. Satyamurthy, 1990, International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes.

[18F]FDDNP PET binding predicts change in executive function in a pilot clinical trial of geriatric depression

G. Small, K. Narr, J. Barrio, 2020, International Psychogeriatrics.

Depression and Anxiety Symptoms Are Associated with Cerebral FDDNP-PET Binding in Middle-Aged and Older Non-Demented Adults

G. Small, V. Kepe, K. Miller, 2009 .

Estrogen use and brain metabolic change in older adults. A preliminary report

G. Small, K. Miller, S-C. Huang, 2001, Psychiatry Research: Neuroimaging.

Probing Estrogen Sulfotransferase-Mediated Inflammation with [11C]-PiB in the Living Human Brain.

J. Ringman, J. Barrio, Sung-Cheng Huang, 2019, Journal of Alzheimer's disease : JAD.

Practical and reliable synthesis of 1,3,4,6-tetra-O-acetyl-2-O-trifluoromethanesulfonyl-beta-D-mannopyranose, a precursor of 2-deoxy-2-[18F]fluoro-D-glucose (FDG).

J. Barrio, N. Satyamurthy, Jie Liu, 2004, Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging.

Tantalum [18O]water target for the production of [18F]fluoride with high reactivity for the preparation of 2-deoxy-2-[18F]fluoro-D-glucose.

C. W. Alvord, J. Barrio, N. Satyamurthy, 2002, Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging.

No-carrier-added 3-(2'-[18F]fluoroethyl)spiperone, a new dopamine receptor-binding tracer for positron emission tomography.

J. Mazziotta, A. Luxen, J. Barrio, 1986, International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology.

Comparative in vivo metabolism of 6-[18F]fluoro-L-dopa and [3H]L-dopa in rats.

A. Luxen, J. Barrio, M. Phelps, 1990, Biochemical pharmacology.

Down Syndrome, Partial Trisomy 21, and Absence of Alzheimer's Disease: The Role of APP.

S. Potkin, G. Small, J. Barrio, 2017, Journal of Alzheimer's disease : JAD.

Longer TOMM40 poly-T variants associated with higher FDDNP-PET medial temporal tau and amyloid binding

G. Small, J. Barrio, L. Ercoli, 2018, PloS one.

Postmortem 3-D brain hemisphere cortical tau and amyloid-β pathology mapping and quantification as a validation method of neuropathology imaging.

G. Small, V. Kepe, K. Miller, 2013, Journal of Alzheimer's disease : JAD.

Prediction of cognitive decline by positron emission tomography of brain amyloid and tau.

G. Small, V. Kepe, K. Miller, 2012, Archives of neurology.

Evaluation of two graphical approaches for regional analysis and parametric mapping of dynamic [18F]FDDNP PET studies

G. Small, V. Kepe, J. Barrio, 2009, 2009 IEEE Nuclear Science Symposium Conference Record (NSS/MIC).

Distribution Volume of 3-O-methyl-6-[F-18]FDOPA in Rat Brain

J. Barrio, N. Satyamurthy, Sung-Cheng Huang, 2000, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Multimodal Imaging of Alzheimer Pathophysiology in the Brain's Default Mode Network

G. Small, V. Kepe, J. Barrio, 2011, International journal of Alzheimer's disease.

Positron emission tomography of brain β-amyloid and τ levels in adults with Down syndrome.

G. Small, V. Kepe, J. Barrio, 2011, Archives of neurology.

Revisiting the physiological roles of SGLTs and GLUTs using positron emission tomography in mice

E. Wright, V. Kepe, J. Barrio, 2016, The Journal of physiology.

Molecular-Imaging Probe 2-(1-{6-[(2-Fluoroethyl)(Methyl) Amino]-2-Naphthyl}Ethylidene) Malononitrile Labels Prion Plaques In Vitro

J. Barrio, A. Petrič, M. Popović, 2003, The Journal of Neuroscience.

O2-02-05 FDDNP-PET binding values from cortical hemispheric surface maps correlate with MMSE scores

P. Thompson, G. Small, K. Hayashi, 2007, Alzheimer's & Dementia.

The Molecular Basis of Disease

J. Barrio, 2004 .

Dissecting molecular mechanisms in the living brain of dementia patients.

G. Small, V. Kepe, J. Barrio, 2009, Accounts of chemical research.

Synthesis and myocardial kinetics of N-13 and C-11 labeled branched-chain L-amino acids.

J. Barrio, M. Phelps, E. Henze, 1983, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Positron Emission Tomography of Brain (cid:2) -Amyloid and Tau Levels in Adults With Down Syndrome

G. Small, V. Kepe, J. Barrio, 2011 .

Response to Letter From Shin and Lee, Entitled 2-(1-{6-[(2-[Fluorine- 18]Fluoroethyl)(Methyl) Amino]-2-Naphthyl} Ethylidene)Malononitrile Positron Emission Tomography Patterns in Nondemented. Populations

G. Small, J. Barrio, L. Ercoli, 2010 .

Response to Letter from Shin and Lee, entitled "FDDNP PET patterns in nondemented populations"

G. Small, J. Barrio, L. Ercoli, 2010, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Synthesis of a new heterobifunctional linker, N-[4-(aminooxy)butyl]maleimide, for facile access to a thiol-reactive 18F-labeling agent.

J. Barrio, N. Satyamurthy, M. Phelps, 2003, Bioconjugate chemistry.

3-(2'-[18F]Fluoroethyl)Spiperone: In vivo Biochemical and Kinetic Characterization in Rodents, Nonhuman Primates, and Humans

J. Mazziotta, J. Hoffman, J. Barrio, 1989, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Metabolic abnormalities adjacent to ischemic myocardium in dogs demonstrated by positron emission tomography

J. Barrio, M. Schwaiger, H. Schelbert, 1984 .

METABOLIC ABNORMALITIES ADJACENT TO ISCHEMIC MYOCARDIUM IN DOGS DEMONSTRATED BY POSITRON TOMOGRAPHY (PET)

J. Barrio, M. Schwaiger, H. Schelbert, 1984 .

Synthesis of 8-[18F]fluoroguanine derivatives: in vivo probes for imaging gene expression with positron emission tomography ☆

S. Cherry, J. Barrio, N. Satyamurthy, 2000 .

Kinetics and mechanism of the defluorination of 8-fluoropurine nucleosides in basic and acidic media

J. Barrio, N. Satyamurthy, Jie Liu, 2006 .

Selective and Practical Synthesis of Penciclovir

J. Barrio, N. Satyamurthy, M. Namavari, 2003 .

Regioselective Fluorination of Substituted Guanines with Dilute F(2): A Facile Entry to 8-Fluoroguanine Derivatives.

J. Barrio, N. Satyamurthy, M. Phelps, 1996, The Journal of organic chemistry.

Intestinal absorption of glucose in mice as determined by positron emission tomography

E. Wright, V. Kepe, J. Barrio, 2018, The Journal of physiology.

Effects of substrate availability on myocardial C-11 palmitate kinetics by positron emission tomography in normal subjects and patients with ventricular dysfunction.

R. Grossman, J. Barrio, M. Phelps, 1986, American heart journal.

Title : Sodium-glucose transporter 2 is a diagnostic and therapeutic target for early-stage lung adenocarcinoma

D. Aberle, J. Barrio, W. Wallace, 2019 .

Analysis of femtomole concentrations of alpha-ketoisocaproic acid in brain tissue by precolumn fluorescence derivatization with 4,5-dimethoxy-1,2-diaminobenzene.

J. Barrio, C. Nissenson, R. Keen, 1993, Analytical biochemistry.

[1-(11)C]palmitic acid: improved radiopharmaceutical preparation.

J. Barrio, G. Robinson, H. Padgett, 1982, The International journal of applied radiation and isotopes.

Lymphoscintigraphy with Tc-99m-labeled dextran.

J. Barrio, E. Henze, H. Schelbert, 1982, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Synthesis of 4-[18F]fluoro-L-m-tyrosine: a model analog for the in vivo assessment of central dopaminergic function.

A. Luxen, J. Barrio, N. Satyamurthy, 1990, International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes.

L-[4-11C]aspartic acid: enzymic synthesis, myocardial uptake, and metabolism

J. Barrio, E. Henze, H. Schelbert, 1982 .

Neural correlates of apathy in late‐life depression: a pilot [18F]FDDNP positron emission tomography study

G. Small, J. Barrio, P. Siddarth, 2017, Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society.

Convenient synthesis of aryl halides from arylamines via treatment of 1-aryl-3,3-dialkyltriazenes with trimethylsilyl halides

J. Barrio, H. Ku, 1981 .

Evaluation of myocardial metabolism, with N-13- and C-11-labeled amino acids and positron computed tomography.

J. Barrio, M. Phelps, E. Henze, 1982, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Defined dimensional changes in enzyme cofactors: fluorescent "stretched-out" analogs of adenine nucleotides.

J. Barrio, D. Scopes, N. Leonard, 1977, Science.

Interactions of fluorescent analogs of adenine nucleotides with pyruvate kinase

Y. Chien, J. Barrio, N. Leonard, 1973, FEBS letters.

Electrophilic and nucleophilic approaches to the synthesis of 3-fluorodiazepam

A. Luxen, J. Barrio, N. Satyamurthy, 1987 .

Radiofluorinated Enzyme Probes of Dopaminergic Function

J. Barrio, N. Satyamurthy, M. Namavari, 1995 .

Synthesis of 6-[18F] and 4-[18F]fluoro-L-m-tyrosines via regioselective radiofluorodestannylation.

J. Barrio, N. Satyamurthy, M. Namavari, 1993, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

4‐[18F]Fluoro‐L‐m‐Tyrosine: An L‐3,4‐Dihydroxyphenylalanine Analog for Probing Presynaptic Dopaminergic Function with Positron Emission Tomography

Scott T. Grafton, A. Luxen, J. Barrio, 1989, Journal of neurochemistry.

N-Fluoro lactams: rapid, mild, and regiospecific fluorinating agents

J. Barrio, N. Satyamurthy, M. Phelps, 1990 .

2Beta-carbomethoxy-3beta-(4- and 2-[18F]fluoromethylphenyl)tropanes: specific probes for in vivo quantification of central dopamine transporter sites.

J. Barrio, N. Satyamurthy, M. Namavari, 1999, Nuclear medicine and biology.

Measurement of C-11 palmitate kinetics after metabolic interventions in normals and patients with cardiomyopathy using positron emission computed tomography

R. Grossman, J. Barrio, M. Phelps, 1982 .

P2-206 In vivo brain imaging of tau aggregation in frontal temporal dementia using [F-18]FDDNP positron emission tomography

G. Small, V. Kepe, K. Miller, 2004, Neurobiology of Aging.

In vivo brain imaging of tangle burden in humans

G. Small, V. Kepe, J. Barrio, 2002, Journal of Molecular Neuroscience.

Radiation Dose Estimates in Humans for 11 CAcetate CAcetate CAcetate Whole-Body PET

J. Barrio, N. Satyamurthy, M. Phelps, 2004 .

Fluorination in aqueous media with elemental fluorine: The synthesis of (F-18)2-FDG

J. Barrio, N. Satyamurthy, G. Bida, 1984 .

Dimensional probes of the enzyme binding sites of adenine nucleotides. Biological effects of widening the adenine ring by 2.4 A.

J. Barrio, D. Scopes, N. Leonard, 1978, Biochemistry.

Amyloid PET: A Questionable Single Primary Surrogate Efficacy Measure on Alzheimer Immunotherapy Trials

A. Alavi, J. Barrio, N. Satyamurthy, 2022, Journal of Alzheimer's disease : JAD.

[18F]Fluoro-beta-fluoromethylene-m-tyrosine derivatives show stereo, geometrical, and regio specificities as in vivo central dopaminergic probes in monkeys.

J. Barrio, N. Satyamurthy, M. Phelps, 1999, Nuclear medicine and biology.

Distribution Volume of Radiolabeled Large Neutral Amino Acids in Brain Tissue

J. Barrio, N. Satyamurthy, D. Stout, 1998, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

CHAPTER 27 – Comparison of Ketamine/Midazolam versus Pentobarbital on [18F]Fluorodopa PET Kinetics in Monkeys

J. Barrio, M. Phelps, Sung-Cheng Huang, 1998 .

6-[18F]Fluoro-l-DOPA metabolism in MPTP-treated monkeys: assessment of tracer methodologies for positron emission tomography

J. Hoffman, J. Barrio, M. Phelps, 1991, Brain Research.

Monitoring Gene Therapy by Positron Emission Tomography

S. Cherry, J. Barrio, N. Satyamurthy, 2003 .

Hemispheric cortical surface map for assessing the rate of changes of regional cortical FDDNP distribution volume versus MMSE score

P. Thompson, G. Small, K. Hayashi, 2007 .

Safety-catch linker strategies for the production of radiopharmaceuticals labeled with positron-emitting isotopes.

J. Barrio, D. Maclean, R. Hale, 2003, Journal of the American Chemical Society.

N-[18F]fluoro-N-alkylsulfonamides: novel reagents for mild and regioselective radiofluorination.

J. Barrio, N. Satyamurthy, G. Bida, 1990, International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes.

Nonlinearity in Modeling Receptor-Binding Ligands

J. Barrio, M. Phelps, Sung-Cheng Huang, 1987 .

Metals suitable for fluorine gas target bodies: first use of aluminum for the production of [18F]F2.

J. Barrio, N. Satyamurthy, A. Bishop, 1996, Nuclear medicine and biology.

C- 11 labeled palmitic acid for the noninvasive evaluation of regional myocardial fatty acid metabolism with positron-computed tomography. II. Kinetics of C- 11 palmitic acid in acutely ischemic myocardium.

J. Barrio, M. Phelps, H. Schelbert, 1982, American heart journal.

Synthesis of modified nucleoside 3',5'-bisphosphates and their incorporation into oligoribonucleotides with T4 RNA ligase.

O. Uhlenbeck, J. Barrio, N. Leonard, 1978, Biochemistry.

Acid-catalyzed thermal decomposition of 1-aryl-3,3-dialkyltriazenes in the presence of nucleophiles

J. Barrio, N. Satyamurthy, M. Phelps, 1990 .

The acid decomposition of 1-aryl-3,3-dialkyltriazenes. Mechanistic changes as a function of aromatic substitution, nucleophile strength, and solvent

J. Barrio, N. Satyamurthy, M. Phelps, 1983 .

Fluorination of substituted veratroles via regioselective mercuration

A. Luxen, J. Barrio, 1988 .

2,4,6-Trisubstituted pyridines. Synthesis, fluorescence, and scintillator properties

J. Barrio, G. Walker, N. Leonard, 1973 .

Remote, semiautomated production of 6-[18F]fluoro-L-dopa for human studies with PET.

M E Phelps, N Satyamurthy, J R Barrio, 1990, International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes.

Electrophilic aromatic radiofluorodemetallation (Hg, Sn) reactions: A convenient route to fluorocatecholamine derivatives

A. Luxen, J. Barrio, M. Perlmutter, 1989 .

On the Stereoselectivity of Fluorine and Acetylhypofluorite Additions to Glycals: The Synthesis of 2-Deoxy-2-Fldorohexoses

J. Barrio, N. Satyamurthy, H. Padgett, 1985 .

Elemental Fluorine to 8-Fluoropurines in One Step

J. Barrio, N. Satyamurthy, M. Phelps, 1996 .

(Z)-β-Fluoromethylene-m-tyrosine: synthesis, crystal structure and fluorination

J. Barrio, N. Satyamurthy, G. Lacan, 1995 .

Cation exchange resin (hydrogen form) assisted decomposition of 1-aryl-3,3-dialkyltriazenes. A mild and efficient method for the synthesis of aryl iodides

J. Barrio, N. Satyamurthy, 1983 .

Cation exchange resin (hydrogen form) assisted decomposition of 1-aryl-3,3-dialkyltriazenes. A mild and efficient method for the synthesis of aryl iodides

J. Barrio, N. Satyamurthy, 1983 .

Efficient conversion of 1-aryl-3, 3-dialkyltriazenes to phenols and oxygen-18 labeled phenols

J. Barrio, N. Satyamurthy, M. Phelps, 1990 .

Stereospecific approach to the synthesis of [18F]2-deoxy-2-fluoro-D-mannose.

A. Luxen, J. Barrio, N. Satyamurthy, 1986, International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes.

PET scanning of brain tau in retired national football league players: preliminary findings.

Vladimir Kepe, Prabha Siddarth, Bennet Omalu, 2013, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

A Transgenic Alzheimer Rat with Plaques, Tau Pathology, Behavioral Impairment, Oligomeric Aβ, and Frank Neuronal Loss

Pasko Rakic, Vladimir Kepe, P. Rakic, 2013, The Journal of Neuroscience.

Syntheses of 4-(2-naphthyl)pyridine derivatives from DDNP

J. Barrio, A. Petrič, M. Koželj, 2005 .

Allosteric activation of aspartate transcarbamylase with a fluorescent nucleotide analogue: linear-benzo-ATP.

J. Barrio, N. Leonard, P. Vanderlijn, 1978, The Journal of biological chemistry.

Synthesis and NMR characterization of 4‐[(2‐tetrahydro‐pyranyloxy)methyl]piperidine and intermediates

J. Barrio, A. Petrič, 1994 .

Acyclic nucleoside analogs: synthesis of open-ring riboside or deoxyriboside analogs lacking C(3') or the C(3')-C(4') bond

J. Barrio, J. D. Bryant, G. E. Keyser, 1979 .

Iodomethylethers from 1,3-dioxolane and 1,3-oxathiolane: preparation of acyclic nucleoside analogs

J. Barrio, J. D. Bryant, G. E. Keyser, 1979 .

A Fluorescent Modification of Adenosine Triphosphate with Activity in Enzyme Systems: 1,N6-Ethenoadenosine Triphosphate

J R Barrio, J. Barrio, N. Leonard, 1972, Science.

Fluorescent Modification of Adenosine 3',5'-Monophosphate: Spectroscopic Properties and Activity in Enzyme Systems

J. Barrio, A. Gilman, C. Villar-Palasi, 1972, Science.

A fluorescent analog of nicotinamide adenine dinucleotide.

J R Barrio, J. Barrio, N. Leonard, 1972, Proceedings of the National Academy of Sciences of the United States of America.

Efficient synthesis of 9-(4-[18F]fluoro-3-hydroxymethylbutyl)guanine ([18F]FHBG) and 9-[(3-[18F]fluoro-1-hydroxy-2-propoxy)methyl]guanine ([18F]FHPG)

J. Barrio, N. Satyamurthy, Jie Liu, 2017 .

Biochemical Parameters in Radiopharmaceutical Design

J. Barrio, 1983 .

2-(N,N-Dialkylamino)ethyl esters of alpha-(3-pyridyl)mandelic acids. Synthesis and pharmacological evaluation.

J. Barrio, H. Huidobro, A. Novelli, 1969, Journal of Medicinal Chemistry.

Production of [18F]F2 using the 16O(3He,p)18F reaction.

J. Barrio, N. Satyamurthy, A. Bishop, 1996, Nuclear medicine and biology.

(E) and (Z)-β-fluoromethylene-m-tyrosines: Resolution and determination of configuration

J. Barrio, N. Satyamurthy, G. Lacan, 1995 .

Isotopic and nuclear analytical techniques in biological systems: A critical survey

J. Barrio, K. Kasprzak, K. Randerath, 1991 .

The Value of In Vitro Binding as Predictor of In Vivo Results: A Case for [18F]FDDNP PET

G. Small, J. Barrio, N. Satyamurthy, 2018, Molecular Imaging and Biology.

Synthesis of stereo (R and S) and geometric (E and Z) isomers of [18F]fluoro-beta-fluoromethylene-m-tyrosine derivatives: in vivo probes of central dopaminergic function.

J. Barrio, N. Satyamurthy, G. Lacan, 1999, Nuclear medicine and biology.

Regioselective synthesis of 6-fluorodopamine, 6-fluoro-m-tyramine and 4-fluoro-m-tyramine using elemental fluorine, oxygen difluoride and acetyl hypofluorite

J. Barrio, N. Satyamurthy, M. Namavari, 1995 .

Synthesis of 6-[18F]fluorodopamine, 6-[18F]fluoro-m-tyramine and 4-[18F]fluoro-m-tyramine

J. Barrio, N. Satyamurthy, M. Namavari, 1995 .

The elusive 8-fluoroadenosine

J. Barrio, N. Satyamurthy, M. Namavari, 1998 .

Protein binding in patients with late-life depression.

G. Small, Anand R. Kumar, V. Kepe, 2011, Archives of general psychiatry.

A tracer kinetic model for 18F-FHBG for quantitating herpes simplex virus type 1 thymidine kinase reporter gene expression in living animals using PET.

Sanjiv S Gambhir, Nagichettiar Satyamurthy, J. Barrio, 2004, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

A direct method for the preparation of 2-hydroxyethoxymethyl derivatives of guanine, adenine, and cytosine.

J. Barrio, J. D. Bryant, G. E. Keyser, 1980, Journal of Medicinal Chemistry.

Attachment of a fluorescent label to 4-thiouracil and 4-thiouridine.

J. Barrio, N. Leonard, J. Secrist, 1971, Biochemical and biophysical research communications.

Specific and fluorescent modifications of cytidine.

J. Barrio, N. Leonard, 1973, Journal of the American Chemical Society.

Fluorescent photoaffinity labeling: adenosine 3',5'-cyclic monophosphate receptor sites.

E. Blout, J. Barrio, N. Leonard, 1978, Proceedings of the National Academy of Sciences of the United States of America.

Molecular imaging of lymphoid organs and immune activation using positron emission tomography with a new 18F-labeled 2′-deoxycytidine analog

Michael E. Phelps, Jorge R. Barrio, Nagichettiar Satyamurthy, 2008, Nature Medicine.

A DIRECT METHOD FOR THE PREPARATION OF 2-HYDROXYETHOXYMETHYL DERIVATIVES OF GUANINE, ADENINE, AND CYTOSINE

J. Barrio, J. D. Bryant, G. E. Keyser, 1980 .

1,N6-Etheno-bridged adenines and adenosines. Alkyl substitution, fluorescence properties, and synthetic applications

J. Barrio, N. Leonard, P. D. Sattsangi, 1980 .

Species responsible for the fluorescence of 3,N4-ethenocytidine.

J. Barrio, N. Leonard, B. Gruber, 1976, Journal of the American Chemical Society.

Memory and Brain Amyloid and Tau Effects of a Bioavailable Form of Curcumin in Non-Demented Adults: A Double-Blind, Placebo-Controlled 18-Month Trial.

G. Small, Zhaoping Li, K. Miller, 2017, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Current and future uses of neuroimaging for cognitively impaired patients

Paul M Thompson, Vladimir Kepe, P. Thompson, 2008, The Lancet Neurology.

Seeing is believing: Non‐invasive, quantitative and repetitive imaging of reporter gene expression in living animals, using positron emission tomography

Krzysztof P Bobinski, S. Cherry, J. Barrio, 2000, Journal of neuroscience research.

In vivo characterization of chronic traumatic encephalopathy using [F-18]FDDNP PET brain imaging

Sung-Cheng Huang, Koon-Pong Wong, Vladimir Kepe, 2015, Proceedings of the National Academy of Sciences.

Modifiable Risk Factors and Brain Positron Emission Tomography Measures of Amyloid and Tau in Nondemented Adults with Memory Complaints.

G. Small, K. Miller, J. Barrio, 2016, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Synthesis of 4-(5-[18F]fluoromethyl-3-phenylisoxazol-4-yl)benzenesulfonamide, a new [18F]fluorinated analogue of valdecoxib, as a potential radiotracer for imaging cyclooxygenase-2 with positron emission tomography.

J. Barrio, N. Satyamurthy, M. Phelps, 2005, Bioorganic & medicinal chemistry letters.

Positron emission tomography imaging of adenoviral-mediated transgene expression in liver cancer patients.

J. Barrio, N. Satyamurthy, M. Phelps, 2005, Gastroenterology.

Whole body skeletal imaging with [18F]fluoride ion and PET.

R A Hawkins, N Satyamurthy, C K Hoh, 1993, Journal of computer assisted tomography.

Indirect monitoring of endogenous gene expression by positron emission tomography (PET) imaging of reporter gene expression in transgenic mice.

Sanjiv S Gambhir, Michael E Phelps, Nagichettiar Satyamurthy, 2002, Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging.

Monitoring antiproliferative responses to kinase inhibitor therapy in mice with 3'-deoxy-3'-18F-fluorothymidine PET.

Michael E Phelps, Wolfgang A Weber, Nagichettiar Satyamurthy, 2005, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Regional distribution of SGLT activity in rat brain in vivo.

E. Wright, V. Kepe, J. Barrio, 2013, American journal of physiology. Cell physiology.

Specific estrogen sulfotransferase (SULT1E1) substrates and molecular imaging probe candidates

Vladimir Kepe, Nagichettiar Satyamurthy, G. Small, 2010, Proceedings of the National Academy of Sciences.

In vivo Cerebral Protein Synthesis Rates with Leucyl-Transfer RNA Used as a Precursor Pool: Determination of Biochemical Parameters to Structure Tracer Kinetic Models for Positron Emission Tomography

J. Barrio, Sung-Cheng Huang, R. Hawkins, 1989, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Synthesis of 3β-(4-[18F]fluoromethylphenyl)- and 3β-(2-[18F] fluoromethylphenyl)tropane-2β-carboxylic acid methyl esters: new ligands for mapping brain dopamine transporter with positron emission tomography

J. Barrio, N. Satyamurthy, Sung-Cheng Huang, 1999 .

Sodium-glucose transporter 2 is a diagnostic and therapeutic target for early-stage lung adenocarcinoma

D. Aberle, J. Barrio, Jie Liu, 2018, Science Translational Medicine.

Sustained regional abnormalities in cardiac metabolism after transient ischemia in the chronic dog model.

J. Barrio, M. Phelps, M. Schwaiger, 1985, Journal of the American College of Cardiology.

C-11 palmitate for the noninvasive evaluation of regional myocardial fatty acid metabolism with positron-computed tomography. IV. In vivo evaluation of acute demand-induced ischemia in dogs.

J. Barrio, M. Phelps, E. Henze, 1983, American heart journal.

PET of Brain Prion Protein Amyloid in Gerstmann–Sträussler–Scheinker Disease

Karen Miller, Sung-Cheng Huang, Grega Repovs, 2010, Brain pathology.

Amyloid imaging in distinguishing atypical prion disease from Alzheimer disease

B L Miller, J R Barrio, G. Small, 2007, Neurology.

Prediction of cognitive decline based on hemispheric cortical surface maps of FDDNP PET

Paul M. Thompson, Andrea D. Klunder, Kiralee M. Hayashi, 2012, NeuroImage.

Quantitative analysis of [18F]FDDNP PET using subcortical white matter as reference region

Sung-Cheng Huang, Gary W. Small, Koon-Pong Wong, 2008, European Journal of Nuclear Medicine and Molecular Imaging.

FLUORINATION OF (E)-BETA -(FLUOROMETHYLENE)-M-TYROSINE : REGIOSELECTIVE SYNTHESIS OF 4-FLUORO-(E)-BETA -(FLUOROMETHYLENE)-M-TYROSINE

J. Barrio, N. Satyamurthy, G. Lacan, 1995 .

The 2,6‐Disubstituted Naphthalene Derivative FDDNP Labeling Reliably Predicts Congo Red Birefringence of Protein Deposits in Brain Sections of Selected Human Neurodegenerative Diseases

Gaj Vidmar, Vladimir Kepe, V. Kepe, 2006, Brain pathology.

Amyloid and tau imaging, neuronal losses and function in mild cognitive impairment

G. Small, V. Kepe, S-C. Huang, 2008, The journal of nutrition, health & aging.

Blood-brain barrier and neuronal membrane transport of 6-[18F]fluoro-L-DOPA.

J. Barrio, N. Satyamurthy, M. Namavari, 2001, Biochemical pharmacology.

Biochemical, neuropathological, and neuroimaging characteristics of early-onset Alzheimer's disease due to a novel PSEN1 mutation

G. Small, L. Apostolova, A. Goate, 2011, Neuroscience Letters.

High-Yield, Automated Radiosynthesis of 2-(1-{6-[(2-[18F]Fluoroethyl)(methyl)amino]-2-naphthyl}ethylidene)malononitrile ([18F]FDDNP) Ready for Animal or Human Administration

Vladimir Kepe, Jorge R. Barrio, Nagichettiar Satyamurthy, 2006, Molecular Imaging and Biology.

Brain pathology and neuronal losses in the living brain of Alzheimer's patients

G. Small, V. Kepe, J. Barrio, 2006 .

In vitro detection of (S)-naproxen and ibuprofen binding to plaques in the Alzheimer’s brain using the positron emission tomography molecular imaging probe 2-(1-{6-[(2-[18F]fluoroethyl)(methyl)amino]-2-naphthyl}ethylidene)malononitrile

V. Kepe, J. Barrio, N. Satyamurthy, 2003, Neuroscience.

Serotonin 1A receptors in the living brain of Alzheimer's disease patients.

Sung-Cheng Huang, Michael E Phelps, Vladimir Kepe, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Design, Syntheses, and in Vitro Evaluation of New Fluorine-18 Radiolabeled Tau-Labeling Molecular Probes.

V. Kepe, J. Barrio, A. Petrič, 2017, Journal of medicinal chemistry.

PET imaging of neuropathology in tauopathies: progressive supranuclear palsy.

J. Mazziotta, G. Small, V. Kepe, 2013, Journal of Alzheimer's disease : JAD.

Noninvasive methods for quantitating blood time-activity curves from mouse PET images obtained with fluorine-18-fluorodeoxyglucose.

P K Banerjee, S R Cherry, C K Hoh, 1998, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Retention and clearance of C-11 palmitic acid in ischemic and reperfused canine myocardium.

J. Barrio, M. Phelps, M. Schwaiger, 1985, Journal of the American College of Cardiology.

Influence of cognitive status, age, and APOE-4 genetic risk on brain FDDNP positron-emission tomography imaging in persons without dementia.

Michael E Phelps, Paul M Thompson, Vladimir Kepe, 2009, Archives of general psychiatry.

Investigation of a new input function validation approach for dynamic mouse microPET studies.

Sung-Cheng Huang, Hsiao-Ming Wu, David B Stout, 2004, Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging.

Flavin 1, N 6 -ethenoadenine dinucleotide: dynamic and static quenching of fluorescence.

J R Barrio, J. Barrio, G. Weber, 1973, Proceedings of the National Academy of Sciences of the United States of America.

L-[1-11C]leucine: routine synthesis by enzymatic resolution.

J. Barrio, J. Ropchan, N. Macdonald, 1983, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Electronic Generators for the Production of Positron-Emitter Labeled Radiopharmaceuticals. Where Would PET Be Without Them?

Michael E. Phelps, Jorge R. Barrio, N Satyamurthy, 1999, Clinical positron imaging : official journal of the Institute for Clinical P.E.T.

Self-reported memory impairment and brain PET of amyloid and tau in middle-aged and older adults without dementia

G. Small, V. Kepe, K. Miller, 2012, International Psychogeriatrics.

Correlation of brain amyloid with “aerobic glycolysis”: A question of assumptions?

J. Barrio, M. Phelps, 2010, Proceedings of the National Academy of Sciences.

Functional expression of SGLTs in rat brain.

E. Wright, V. Kepe, J. Barrio, 2010, American journal of physiology. Cell physiology.

Positron emission tomography of sodium glucose cotransport activity in high grade astrocytomas

E. Wright, V. Kepe, J. Barrio, 2018, Journal of Neuro-Oncology.

C- 11 labeled palmitic acid for the noninvasive evaluation of regional myocardial fatty acid metabolism with positron-computed tomography. I. Kinetics of C- 11 palmitic acid in normal myocardium.

J. Barrio, D. Kuhl, M. Phelps, 1982, American heart journal.

Dapagliflozin Binds Specifically to Sodium-Glucose Cotransporter 2 in the Proximal Renal Tubule.

E. Wright, V. Kepe, J. Barrio, 2017, Journal of the American Society of Nephrology : JASN.

A semi-automated workflow solution for multimodal neuroimaging: application to patients with traumatic brain injury

V. Kepe, J. Barrio, Sung-Cheng Huang, 2015, Brain Informatics.

FDDNP-PET Tau Brain Protein Binding Patterns in Military Personnel with Suspected Chronic Traumatic Encephalopathy1.

G. Small, J. Barrio, P. Siddarth, 2018, Journal of Alzheimer's disease : JAD.

Proton irradiation of [18O]O2: production of [18F]F2 and [18F]F2 + [18F] OF2.

J. Barrio, N. Satyamurthy, A. Bishop, 1996, Nuclear medicine and biology.

Amyloid-β positron emission tomography imaging probes: a critical review.

Habib Zaidi, Sung-Cheng Huang, Abass Alavi, 2013, Journal of Alzheimer's disease : JAD.

Remote, semiautomated production of F-18-labeled 2-deoxy-2-fluoro-D-glucose.

J. Barrio, D. Kuhl, N. Macdonald, 1981, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Enzymatic synthesis of [1-11C]pyruvic acid, L-[1-11C]lactic acid and L-[1-11C]alanine via DL-[1-11C]alanine.

J. Barrio, J. Ropchan, 1984, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

An automated high pressure reaction vessel for routine preparation of short-lived radiopharmaceuticals.

A. R. Ricci, J. Barrio, J. Ropchan, 1986, International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes.

Visualizing pathology deposits in the living brain of patients with Alzheimer's disease.

Sung-Cheng Huang, Vladimir Kepe, Nagichettiar Satyamurthy, 2006, Methods in enzymology.

Depression and anxiety symptoms are associated with cerebral FDDNP-PET binding in middle-aged and older nondemented adults.

G. Small, V. Kepe, K. Miller, 2009, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Mood, cognition and in vivo protein imaging: the emerging nexus in clinical neuroscience

G. Small, Anand R. Kumar, V. Kepe, 2008, International journal of geriatric psychiatry.

Postmortem Autopsy‐Confirmation of Antemortem [F‐18]FDDNP‐PET Scans in a Football Player With Chronic Traumatic Encephalopathy

G. Small, J. Barrio, L. Ercoli, 2018, Neurosurgery.

Seeing is believing: neuroimaging adds to our understanding of cerebral pathology

Vladimir Kepe, G. Small, V. Kepe, 2006, Current opinion in psychiatry.

Structural selectivity of human SGLT inhibitors.

D. Loo, E. Wright, V. Kepe, 2012, American journal of physiology. Cell physiology.

Positron-Emission Tomography Reporter Gene Expression Imaging in Rat Myocardium

Sanjiv S Gambhir, Arion F Chatziioannou, Nagichettiar Satyamurthy, 2003, Circulation.

Imaging and therapeutics: the role of neuronal transport in the regional specificity of L-DOPA accumulation in brain.

J. Langston, J. Barrio, N. Satyamurthy, 2002, Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging.

In Vivo Brain Plaque and Tangle Burden Mediates the Association Between Diastolic Blood Pressure and Cognitive Functioning in Nondemented Adults.

Florence F. Roussotte, G. Small, K. Narr, 2018, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Radiofluorinated L-m-Tyrosines: New In-Vivo Probes for Central Dopamine Biochemistry

S. Cherry, J. Barrio, N. Satyamurthy, 1996, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

The Unit Operations Approach to the Applied to the Synthesis of [1-11C]2-Deoxy-d-Glucose for Routine Clinical Applications

J. Barrio, N. Macdonald, M. Phelps, 1982 .

Chemical reactivity of the 18F electrophilic reagents from the 18O(p,n) 18F gas target systems.

J. Barrio, N. Satyamurthy, A. Bishop, 1996, Nuclear medicine and biology.

Identification and quantitation of gaseous compounds of fluorine generated in [18F]F2 target systems.

J. Barrio, N. Satyamurthy, A. Bishop, 1996, Nuclear medicine and biology.

In vivo assessment of neurotransmitter biochemistry in humans.

J. Barrio, M. Phelps, S. C. Huang, 1988, Annual review of pharmacology and toxicology.

Estimation of Local Cerebral Protein Synthesis Rates with L-[1-11C]Leucine and PET: Methods, Model, and Results in Animals and Humans

J C Mazziotta, M E Phelps, R A Hawkins, 1989, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Kinetic characterization of 13NH3 and [13N]glutamine metabolism in rabbit heart.

J. Barrio, M. Phelps, K. Shine, 1984, The American journal of physiology.

The effects of carbidopa on the metabolism of 6-[18F]fluoro-L-dopa in rats, monkeys and humans.

A. Luxen, J. Hoffman, J. Barrio, 1990, Life sciences.

Assessment of dementia risk in aging adults using both FDG‐PET and FDDNP‐PET imaging

J R Barrio, S Y Bookheimer, G. Small, 2012, International journal of geriatric psychiatry.

Automated image registration for FDOPA PET studies.

M E Phelps, S C Huang, K P Lin, 1996, Physics in medicine and biology.

Automated Movement Correction for Dynamic PET/CT Images: Evaluation with Phantom and Patient Data

Sung-Cheng Huang, Gary W. Small, Koon-Pong Wong, 2014, PloS one.

Concepts and Techniques Used in Metabolic Tracer Studies

J. Barrio, N. Satyamurthy, M. Phelps, 1986 .

Neuroreceptor Assay with Positron Emission Tomography: Equilibrium versus Dynamic Approaches

M E Phelps, J R Barrio, J. Barrio, 1986, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Does 2-FDG PET Accurately Reflect Quantitative In Vivo Glucose Utilization?

A. Alavi, J. Barrio, N. Satyamurthy, 2019, The Journal of Nuclear Medicine.

Metabolic maturation of the brain: A study of local cerebral protein synthesis in the developing cat

J. Barrio, D. Hovda, H. Chugani, 2006, Brain Research.

C-11 palmitate for the noninvasive evaluation of regional myocardial fatty acid metabolism with positron computed tomography. III. In vivo demonstration of the effects of substrate availability on myocardial metabolism.

J. Barrio, M. Phelps, E. Henze, 1983, American heart journal.

Effects of Large Neutral Amino Acid Concentrations on 6-[F-18]Fluoro-L-DOPA Kinetics

J. Barrio, Sung-Cheng Huang, M. Raleigh, 1998, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Progressive Focal Gray Matter Volume Loss in a Former High School Football Player: A Possible Magnetic Resonance Imaging Volumetric Signature for Chronic Traumatic Encephalopathy.

G. Small, J. Barrio, C. Raji, 2016, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Cross-Sectional and Longitudinal Cognitive Correlates of FDDNP PET and CSF Amyloid-β and Tau in Parkinson's Disease1.

J. Barrio, F. Valldeoriola, M. Marti, 2016, Journal of Alzheimer's disease : JAD.

Radiation dose estimates in humans for (11)C-acetate whole-body PET.

Magnus Dahlbom, Michael E Phelps, David B Stout, 2004, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Welcome to the Future

Jorge R. Barrio, J. Barrio, 2010, Molecular Imaging and Biology.

Estimation of rabbit myocardial metabolic rate for glucose using fluorodeoxyglucose.

M E Phelps, J R Barrio, K I Shine, 1982, The American journal of physiology.

Biological imaging and the molecular basis of dopaminergic diseases.

M E Phelps, J R Barrio, J. Barrio, 1997, Biochemical pharmacology.

A semi-automated workflow solution for multimodal neuroimaging: application to patients with traumatic brain injury

V. Kepe, J. Barrio, Sung-Cheng Huang, 2016, Brain Informatics.

Striatal Kinetic Modeling of FDOPA with a Cerebellar-Derived Constraint on the Distribution Volume of 3OMFD: A PET Investigation using Non-Human Primates

Michael E. Phelps, Sung-Cheng Huang, David B. Stout, 2000, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

The assessment of the non-equilibrium effect in the 'Patlak analysis' of Fdopa PET studies.

M E Phelps, J R Barrio, J. Barrio, 1995, Physics in medicine and biology.

P-79: The effect of blood pressure control on cognitive function (the focus study)

J. Barrio, E. Jacobson, S. Salehmoghaddam, 2001 .

Suboptimal validity of amyloid imaging-based diagnosis and management of Alzheimer’s disease: why it is time to abandon the approach

T. Werner, A. Alavi, J. Barrio, 2019, European Journal of Nuclear Medicine and Molecular Imaging.

Exploring a Mathematical Model for the Kinetics of β-Amyloid Molecular Imaging Probes through a Critical Analysis of Plaque Pathology

V. Kepe, J. Barrio, Sung-Cheng Huang, 2006, Molecular Imaging and Biology.

Fddnp Binding Using Mr Derived Cortical Surface Maps

Paul M. Thompson, Andrea D. Klunder, Kiralee M. Hayashi, 2022 .

Passive Alzheimer’s immunotherapy: A promising or uncertain option?

A. Alavi, N. Robakis, J. Barrio, 2023, Ageing Research Reviews.

FDG PET (and MRI) for Monitoring Immunotherapy in Alzheimer Disease

A. Alavi, J. Barrio, P. Høilund-Carlsen, 2023, Clinical nuclear medicine.

In vitro and in vivo binding characteristics of two biological probes for plaques and tangles in alzheimer's disease

G. Small, V. Kepe, J. Barrio, 2001 .

Circular Inference in Dementia Diagnostics.

T. Werner, A. Alavi, J. Barrio, 2018, Journal of Alzheimer's disease : JAD.

FDG-PET versus Amyloid-PET Imaging for Diagnosis and Response Evaluation in Alzheimer’s Disease: Benefits and Pitfalls

A. Alavi, J. Barrio, P. Høilund-Carlsen, 2023, Diagnostics.

Criteria for the tracer kinetic measurement of cerebral protein synthesis in humans with positron emission tomography

J. Mazziotta, J. Barrio, M. Phelps, 1984, Annals of neurology.

A fully automated one pot synthesis of 9-(4-[18F]fluoro-3-hydroxymethylbutyl) guanine for gene therapy studies.

J. Barrio, N. Satyamurthy, J. Martí-Climent, 2002, Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging.

Selective and Practical Synthesis of Penciclovir.

J. Barrio, N. Satyamurthy, M. Namavari, 2004 .

The Anti-Amyloid Monoclonal Antibody Lecanemab: 16 Cautionary Notes.

A. Alavi, N. Robakis, J. Barrio, 2023, Journal of Alzheimer's disease : JAD.

Neural correlates of apathy in late-life depression: a pilot [18F]FDDNP PET study: Apathy in late-life depression

G. Small, J. Barrio, P. Siddarth, 2017 .

Functionalization of a viscosity-sensitive fluorophore for probing of biological systems.

J. Barrio, A. Petrič, A. Jacobson, 1998, Bioorganic & medicinal chemistry letters.

Psychological well-being and regional brain amyloid and tau in mild cognitive impairment.

G. Small, K. Miller, J. Barrio, 2014, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Effects of anoxia on kinetics of [13N] glutamate and 13NH3 metabolism in rabbit myocardium.

J. Barrio, M. Phelps, K. Shine, 1987, Circulation research.

6-[18F]Fluoro-L-DOPA kinetics with PET: Correlation with its biochemical metabolism in normal and MPTP-treated monkeys

J. Hoffman, S-C. Huang, J. Barrio, 1991 .

Repetitive, non-invasive imaging of the dopamine D2 receptor as a reporter gene in living animals

S. Cherry, J. Barrio, N. Satyamurthy, 1999, Gene Therapy.

Response to Letter About Memory and Brain Effects of Curcumin.

G. Small, J. Barrio, P. Siddarth, 2018, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Dicyanovinylnaphthalenes for neuroimaging of amyloids and relationships of electronic structures and geometries to binding affinities

Y. Li, V. Kepe, J. Barrio, 2012, Proceedings of the National Academy of Sciences.

Flurbiprofen derivatives in Alzheimer's disease: synthesis, pharmacokinetic and biological assessment of lipoamino acid prodrugs.

V. Kepe, J. Barrio, S. Salmaso, 2008, Bioconjugate chemistry.

Etheno-substituted nucleotides and coenzymes: fluorescence and biological activity.

J. Barrio, N. Leonard, 1984, CRC critical reviews in biochemistry.

Computer-controlled radiochemical synthesis: a chemistry process control unit for the automated production of radiochemicals.

N Satyamurthy, J R Barrio, A. Luxen, 1989, International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes.

The effects of carbidopa administration on 6-[18F]fluoro-L-dopa kinetics in positron emission tomography.

J C Mazziotta, M E Phelps, J M Hoffman, 1992, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

National Cancer Institute workshop statement: Advances in clinical imaging using positron emission tomography, September 14-16, 1988

J. Mazziotta, M. Mintun, S. Larson, 1990 .

L-6-[18F]Fluoro-DOPA Metabolism in Monkeys and Humans: Biochemical Parameters for the Formulation of Tracer Kinetic Models with Positron Emission Tomography

M E Phelps, Scott T. Grafton, N Satyamurthy, 1991, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

A mutant herpes simplex virus type 1 thymidine kinase reporter gene shows improved sensitivity for imaging reporter gene expression with positron emission tomography.

M. Black, J. Barrio, S. Gambhir, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Monitoring gene therapy with reporter gene imaging.

J. Barrio, N. Satyamurthy, S. Gambhir, 2001, Seminars in nuclear medicine.

Imaging adenoviral-directed reporter gene expression in living animals with positron emission tomography.

S. Cherry, J. Barrio, N. Satyamurthy, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Assays for noninvasive imaging of reporter gene expression.

J. Barrio, S. Gambhir, S. Gambhir, 1999, Nuclear medicine and biology.

Welcome to the Future

J. Barrio, 2010, Molecular Imaging and Biology.

New IDEAS Amyloid Imaging 2021 Study: Running in Place with Ineffective Anti-Amyloid Treatments for Alzheimer's Disease Patients.

A. Alavi, J. Barrio, P. Whitehouse, 2021, Journal of Alzheimer's disease : JAD.

Novel Fluorescent Reactive Dyes as Intermediates for the Preparation of UV and Vis Wavelength Fluorescent Probes

J. Barrio, A. Petrič, Tatjana Špes, 1998 .

6‐[18F]Fluoro‐L‐DOPA probes dopamine turnover rates in central dopaminergic structures

J C Mazziotta, M E Phelps, J M Hoffman, 1990, Journal of neuroscience research.

Models for in vivo Kinetic Interactions of Dopamine D2-Neuroreceptors and 3-(2'-[18F]Fluoroethyl)Spiperone Examined with Positron Emission Tomography

J C Mazziotta, M E Phelps, J M Hoffman, 1989, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

In vivo [F-18]FDDNP microPET imaging of brain B-amyloid in a transgenic rat model of Alzheimer’s disease

G. Small, V. Kepe, J. Barrio, 2005, Alzheimer's & Dementia.

Differential FDDNP PET patterns in nondemented middle-aged and older adults.

G. Small, V. Kepe, K. Miller, 2009, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Previously Published Works Ucla Title: Psychological Well-being and Regional Brain Amyloid and Tau in Mild Cognitive Impairment Psychological Well-being and Regional Brain Amyloid and Tau in Mild Cognitive Impairment Nih Public Access Author Manuscript Introduction

J. Barrio, L. Ercoli, P. Siddarth, 2022 .

Automated VOI analysis in 18 F-FDDNP PET using structural warping: Validation through classification of Alzheimer's disease patients

Sung-Cheng Huang, Gary W. Small, Jorge R. Barrio, 2010 .

Dicyanovinylnaphthalenes for neuroimaging of amyloids and relationships of electronic structures and geometries to binding affinities

Y. Li, V. Kepe, J. Barrio, 2012, Proceedings of the National Academy of Sciences.

Memory and Brain Amyloid and Tau Effects of a Bioavailable Form of Curcumin in Non-Demented Adults: A Double-Blind, Placebo-Controlled 18-Month Trial.

G. Small, Zhaoping Li, K. Miller, 2017, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

Down Syndrome, Partial Trisomy 21, and Absence of Alzheimer's Disease: The Role of APP.

S. Potkin, G. Small, J. Barrio, 2017, Journal of Alzheimer's disease : JAD.

Biochemical, neuropathological, and neuroimaging characteristics of early-onset Alzheimer's disease due to a novel PSEN1 mutation

G. Small, L. Apostolova, A. Goate, 2011, Neuroscience Letters.

Comparative evaluation of Logan and relative-equilibrium graphical methods for parametric imaging of dynamic [18F]FDDNP PET determinations

Magnus Dahlbom, Sung-Cheng Huang, Gary W. Small, 2012, NeuroImage.

Comparison of simplified methods for quantitative analysis of [18F]FDDNP PET data

Sung-Cheng Huang, Koon-Pong Wong, G. Small, 2007, 2007 IEEE Nuclear Science Symposium Conference Record.

Crystal and molecular structure of 3,N4-ethenocytidine hydrochloride. A study of the dimensions and molecular interactions of the fluorescent epsilon-cytidine system.

J. Barrio, I. Paul, A. Wang, 1976, Journal of the American Chemical Society.

A Transgenic Alzheimer Rat with Plaques, Tau Pathology, Behavioral Impairment, Oligomeric Aβ, and Frank Neuronal Loss

P. Rakic, V. Kepe, J. Barrio, 2013, The Journal of Neuroscience.