D. Brown

发表

The let-7 microRNA represses cell proliferation pathways in human cells.

F. Slack, Charles D. Johnson, A. Esquela-Kerscher, 2007, Cancer research.

Systemic Delivery of a miR34a Mimic as a Potential Therapeutic for Liver Cancer

D. Brown, C. Daige, J. Wiggins, 2014, Molecular Cancer Therapeutics.

A Phase I Pharmacologic Study of Necitumumab (IMC-11F8), a Fully Human IgG1 Monoclonal Antibody

C. Livi, D. Brown, D. Rakheja, 2016 .

RAS Is Regulated by the let-7 MicroRNA Family

F. Slack, M. Byrom, Jaclyn Shingara, 2005, Cell.

Identification of miRNA Changes in Alzheimer's Disease Brain and CSF Yields Putative Biomarkers and Insights into Disease Pathways

A. Roses, Caifu Chen, K. Kelnar, 2008 .

Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34.

K. Kelnar, D. Brown, J. Wiggins, 2010, Cancer research.

The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44.

K. Kelnar, D. Brown, J. Wiggins, 2011, Nature medicine.

The promise of microRNA replacement therapy.

D. Brown, A. Bader, M. Winkler, 2010, Cancer research.

The let-7 microRNA reduces tumor growth in mouse models of lung cancer

F. Slack, A. Esquela-Kerscher, J. Weidhaas, 2008, Cell cycle.

Regression of murine lung tumors by the let-7 microRNA

F. Slack, J. Weidhaas, K. Kelnar, 2009, Oncogene.

miR-10a overexpression is associated with NPM1 mutations and MDM4 downregulation in intermediate-risk acute myeloid leukemia.

T. Davison, K. Kelnar, D. Ovcharenko, 2011, Experimental hematology.

Distinct microRNA expression profiles in prostate cancer stem/progenitor cells and tumor-suppressive functions of let-7.

K. Kelnar, D. Brown, A. Vlassov, 2012, Cancer research.

RNA Interference Technology: Six methods of inducing RNAi in mammalian cells

M. Byrom, D. Brown, P. Ku, 2005 .

The microRNA miR-34 a inhibits prostate cancer stem cells and metastasis by directly repressing CD 44

K. Kelnar, D. Brown, J. Wiggins, 2010 .

High-throughput RNAi screening in vitro: from cell lines to primary cells.

K. Kelnar, D. Ovcharenko, D. Brown, 2005, RNA.

Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in mice.

F. Slack, J. Weidhaas, D. Brown, 2011, Molecular therapy : the journal of the American Society of Gene Therapy.

MicroRNA-494 Within an Oncogenic MicroRNA Megacluster Regulates G1/S Transition in Liver Tumorigenesis Through Suppression of Mutated in Colorectal Cancer

Aaron N. Chang, A. Balakrishnan, D. Brown, 2013, Hepatology.

Applying small RNA molecules to the directed treatment of human diseases: realizing the potential

D. Brown, A. Bader, L. Ford, 2008, Expert opinion on therapeutic targets.

An optimized isolation and labeling platform for accurate microRNA expression profiling.

Jeffrey Shelton, Emmanuel Labourier, J. Shelton, 2005, RNA.

Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes.

Yusuke Yamamoto, Takahiro Ochiya, Fumitaka Takeshita, 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

Combined Replenishment of miR-34a and let-7b by Targeted Nanoparticles Inhibits Tumor Growth in Neuroblastoma Preclinical Models.

D. Ferrari, D. Brown, D. Ribatti, 2020, Small.

SiRNA strategy against overexpression of extracellular matrix in diabetic retinopathy.

D. Brown, T. Oshitari, Sayon Roy, 2005, Experimental eye research.

Genome-scale microRNA and small interfering RNA screens identify small RNA modulators of TRAIL-induced apoptosis pathway.

Charles D. Johnson, K. Kelnar, D. Ovcharenko, 2007, Cancer research.

Pathway Identify Small RNA Modulators of TRAIL-Induced Apoptosis Genome-Scale MicroRNA and Small Interfering RNA Screens

Charles D. Johnson, K. Kelnar, D. Ovcharenko, 2007 .

Identification of miR-34a as a potent inhibitor of prostate cancer progenitor cells and metastasis by directly repressing CD44

K. Kelnar, D. Brown, J. Wiggins, 2010, Nature Medicine.

The microRNA miR-34 a inhibits prostate cancer stem cells and metastasis by directly repressing CD 44

K. Kelnar, D. Brown, J. Wiggins, 2010 .

Distinct microRNA expression profiles in prostate cancer stem/progenitor cells and tumor-suppressive functions of let-7.

K. Kelnar, D. Brown, A. Vlassov, 2012, Cancer research.

MRX34, a liposomal miR-34 mimic and potential first-in-class microRNA therapeutic: activity in animal models of liver cancer.

D. Brown, C. Daige, J. Wiggins, 2016 .

Revi The Andre Abst Mic RNAs

D. Brown, M. Winkler, G. Bader, 2010 .

O3-02-07: Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways

A. Roses, Caifu Chen, K. Kelnar, 2008, Alzheimer's & Dementia.

Identification of miR-34a as a potent inhibitor of prostate cancer progenitor cells and metastasis by directly repressing CD44

K. Kelnar, D. Brown, J. Wiggins, 2010, Nature Medicine.