S. Henderson

发表

APOBEC-mediated cytosine deamination links PIK3CA helical domain mutations to human papillomavirus-driven tumor development.

S. Henderson, A. Chakravarthy, Xiaoping Su, 2014, Cell reports.

Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production

S. Henderson, C. Boshoff, S. Moncada, 2007, Proceedings of the National Academy of Sciences.

Comparative Hi-C Reveals that CTCF Underlies Evolution of Chromosomal Domain Architecture

D. Odom, A. Tanay, S. Henderson, 2015, Cell reports.

Predicting biomarkers for ovarian cancer using gene-expression microarrays

S. Henderson, C. Boshoff, T. Adib, 2004, British Journal of Cancer.

G-CSF mobilizes CD34+ regulatory monocytes that inhibit graft-versus-host disease

Clare L. Bennett, S. Henderson, M. Mohty, 2015, Science Translational Medicine.

TBK1 and IKKε prevent TNF-induced cell death by RIPK1 phosphorylation

S. Henderson, S. Surinova, H. Walczak, 2018, Nature Cell Biology.

Genetic variants alter T-bet binding and gene expression in mucosal inflammatory disease

Graham M Lord, Richard G. Jenner, S. Henderson, 2017, PLoS genetics.

A population of CD4+ T cells with a naïve phenotype stably polarized to the TH1 lineage

Graham M Lord, Richard G. Jenner, S. Henderson, 2020, bioRxiv.

Human Papillomavirus Drives Tumor Development Throughout the Head and Neck: Improved Prognosis Is Associated With an Immune Response Largely Restricted to the Oropharynx.

Andrew Feber, Stephen Henderson, S. Henderson, 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV- tumors

P. Stephens, R. Yelensky, M. Cronin, 2013, Genome Medicine.

DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status.

Peter Simpson, Georgia Chenevix-Trench, Anna Marsh, 2010, American journal of human genetics.

Inhibition of γ‐secretases alters both proliferation and differentiation of mesenchymal stem cells

S. Henderson, A. Flanagan, M. Clements, 2007 .

H3.3K27M Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas.

A. Riccio, S. Henderson, P. Salomoni, 2017, Cancer cell.

A single wave of monocytes is sufficient to replenish the long-term Langerhans cell network after immune injury

Clare L. Bennett, S. Henderson, J. Strid, 2019, bioRxiv.

KSHV Manipulates Notch Signaling by DLL4 and JAG1 to Alter Cell Cycle Genes in Lymphatic Endothelia

S. Henderson, C. Boshoff, A. Pizzey, 2009, PLoS pathogens.

Cell-intrinsic regulation of murine dendritic cell function and survival by prereceptor amplification of glucocorticoid.

Clare L. Bennett, S. Henderson, F. Fallah-Arani, 2013, Blood.

The CD8 and CD4 T-Cell Response against Kaposi's Sarcoma-Associated Herpesvirus Is Skewed Towards Early and Late Lytic Antigens

S. Henderson, C. Boshoff, M. Bower, 2009, PloS one.

Integrated analysis of cervical squamous cell carcinoma cohorts from three continents reveals conserved subtypes of prognostic significance

Mark N. Wass, Ian G. Reddin, Nerissa K. Kirkwood, 2021, Nature Communications.

Peripheral tissues reprogram CD8+ T cells for pathogenicity during graft-versus-host disease

Clare L. Bennett, S. Henderson, V. Plagnol, 2018, JCI insight.

Diagnosing an extra-axial chordoma of the proximal tibia with the help of brachyury, a molecule required for notochordal differentiation

S. Henderson, C. Boshoff, A. Flanagan, 2006, Skeletal Radiology.

Oncogenic transformation of mesenchymal stem cells decreases Nrf2 expression favoring in vivo tumor growth and poorer survival

S. Henderson, C. Boshoff, S. Moncada, 2014, Molecular Cancer.

Brachyury, a crucial regulator of notochordal development, is a novel biomarker for chordomas

S. Henderson, C. Boshoff, T. Jacques, 2006, The Journal of pathology.

Loss of T cell tolerance in the skin following immunopathology is linked to failed restoration of the dermal niche by recruited macrophages

Clare L. Bennett, S. Henderson, L. Jardine, 2022, Cell reports.

Genomics screen in transformed stem cells reveals RNASEH2A, PPAP2C, and ADARB1 as putative anticancer drug targets

S. Henderson, C. Boshoff, J. Funes, 2009, Molecular Cancer Therapeutics.

MicroRNA profiling of peripheral nerve sheath tumours identifies miR-29c as a tumour suppressor gene involved in tumour progression

S. Henderson, A. Flanagan, M. Eskandarpour, 2012, British Journal of Cancer.

A wave of monocytes is recruited to replenish the long-term Langerhans cell network after immune injury

Clare L. Bennett, S. Henderson, J. Strid, 2019, Science Immunology.

KSHV-encoded miRNAs target MAF to induce endothelial cell reprogramming.

Paul Kellam, Dimitrios Lagos, Mark Bower, 2010, Genes & development.

Kaposi sarcoma herpesvirus–induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma

S. Henderson, C. Boshoff, M. Trotter, 2004, Nature Genetics.

Nonhematopoietic antigen blocks memory programming of alloreactive CD8+ T cells and drives their eventual exhaustion in mouse models of bone marrow transplantation.

Clare L. Bennett, G. Freeman, S. Henderson, 2010, The Journal of clinical investigation.

Aberrant paracrine signalling for bone remodelling underlies the mutant histone-driven giant cell tumour of bone

S. Henderson, A. P. Leite, P. Salomoni, 2021, bioRxiv.

A molecular map of mesenchymal tumors

Neil Sebire, D. Guiliano, S. Henderson, 2005, Genome Biology.

EZH2 deficient T-cell acute lymphoblastic leukemia is sensitized to CHK1 inhibition through enhanced replication stress.

S. Henderson, R. D. de Bruin, J. Herrero, 2020, Cancer discovery.

APOBEC3 genes: retroviral restriction factors to cancer drivers.

S. Henderson, T. Fenton, 2015, Trends in molecular medicine.

Trends in Molecular Medicine APOBEC 3 genes : retroviral restriction factors to cancer drivers

S. Henderson, T. Fenton, 2015 .

behavior during angiogenesis to modulate endothelial cell DLL4 The microRNA-30 family targets

S. Henderson, C. Boshoff, R. Monteiro, 2014 .

The microRNA-30 family targets DLL4 to modulate endothelial cell behavior during angiogenesis.

S. Henderson, C. Boshoff, R. Patient, 2012, Blood.

miR-132 regulates antiviral innate immunity through suppression of the p300 transcriptional co-activator

Frances Gotch, Dimitrios Lagos, Stephen Henderson, 2010, Nature Cell Biology.

When defense turns into attack

S. Henderson, A. Chakravarthy, T. Fenton, 2014, Molecular & cellular oncology.

Cell-cell adhesion regulates Merlin/NF2 interaction with the PAF complex

A. Burlingame, S. Henderson, P. Rodriguez-Viciana, 2021, PloS one.

Role for Merlin/NF2 in transcription elongation through interaction with the PAF complex

A. Burlingame, S. Henderson, P. Rodriguez-Viciana, 2019, bioRxiv.

KSHV-initiated notch activation leads to membrane-type-1 matrix metalloproteinase-dependent lymphatic endothelial-to-mesenchymal transition.

L. Aaltonen, S. Henderson, C. Boshoff, 2011, Cell host & microbe.

The Th1 cell regulatory circuitry is largely conserved between human and mouse

Graham M Lord, Richard G. Jenner, S. Henderson, 2021, Life Science Alliance.

H3.3 cooperates with Trp53 loss and PDGFRA gain in mouse embryonic neural progenitor cells to induce invasive high-grade gliomas

Justyna, A. Riccio, S. Henderson, 2017 .

Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma

Tim Fenton, Stephan Beck, Matthias Lechner, 2013, Genome Medicine.

Gene-body hypermethylation of ATM in peripheral blood DNA of bilateral breast cancer patients

J. Peto, S. Henderson, C. Boshoff, 2009, Human molecular genetics.

An MRAS, SHOC2, and SCRIB complex coordinates ERK pathway activation with polarity and tumorigenic growth.

M. Lythgoe, A. Burlingame, S. Henderson, 2013, Molecular cell.

Kaposi's Sarcoma-Associated Herpesvirus Cytotoxic T Lymphocytes Recognize and Target Darwinian Positively Selected Autologous K1 Epitopes

S. Henderson, C. Boshoff, M. Youle, 2003, Journal of Virology.

Transforming activity of Fbxo7 is mediated specifically through regulation of cyclin D/cdk6

S. Henderson, C. Boshoff, J. Funes, 2005, The EMBO journal.

Transforming activity of Fbxo 7 is mediated specifically through regulation of cyclin D / cdk 6

S. Henderson, C. Boshoff, J. Funes, 2005 .

Autologous K 1 Epitopes Target Darwinian Positively Selected Cytotoxic T Lymphocytes Recognize and Kaposi ' s Sarcoma-Associated Herpesvirus

S. Henderson, C. Boshoff, M. Youle, 2003 .

Chondroblastomas but not chondromyxoid fibromas express cytokeratins: an unusual presentation of a chondroblastoma in the metaphyseal cortex of the tibia

S. Henderson, C. Boshoff, A. Flanagan, 2007, Histopathology.

An integrated functional genomics approach identifies the regulatory network directed by brachyury (T) in chordoma

Paul Flicek, Dina Halai, Nadège Presneau, 2012, The Journal of pathology.

Depletion of CD11c+ cells in the CD11c.DTR model drives expansion of unique CD64+ Ly6C+ monocytes that are poised to release TNF-α

Clare L. Bennett, S. Henderson, T. Means, 2015, European Journal of Immunology.

Pro-metastatic gene expression, immune evasion and an altered HPV spectrum characterize an aggressive subtype of cervical cancer

Ian G. Reddin, Nerissa K. Kirkwood, S. Henderson, 2020 .

Herpesviruses shape tumour microenvironment through exosomal transfer of viral microRNAs

S. Henderson, T. Enver, J. Herrero, 2017, PLoS pathogens.

A population of naive‐like CD4+ T cells stably polarized to the TH1 lineage

Graham M Lord, Richard G. Jenner, S. Henderson, 2022, European journal of immunology.

The G-Protein–Coupled Receptor CLR Is Upregulated in an Autocrine Loop with Adrenomedullin in Clear Cell Renal Cell Carcinoma and Associated with Poor Prognosis

Stephen Henderson, Stephen B Fox, Adrian L Harris, 2013, Clinical Cancer Research.

TBK1 and IKKε prevent TNF-induced cell death by RIPK1 phosphorylation

S. Henderson, S. Surinova, H. Walczak, 2018, Nature Cell Biology.

Pro-metastatic gene expression, immune evasion and an altered HPV spectrum characterize an aggressive subtype of cervical cancer

Ian G. Reddin, Nerissa K. Kirkwood, S. Henderson, 2020, bioRxiv.

Inhibition of gamma-secretases alters both proliferation and differentiation of mesenchymal stem cells.

S. Henderson, A. Flanagan, M. Clements, 2007, Cell proliferation.

Gene expression array profile of human osteosarcoma

Tyson V. Sharp, A. Goodship, S. Henderson, 2003, British Journal of Cancer.

Adrenomedullin Haploinsufficiency Predisposes to Secondary Lymphedema

S. Henderson, C. Boshoff, U. Qureshi, 2013, The Journal of investigative dermatology.

Comparative HiC Reveals that CTCF Underlies Evolution of Chromosomal Domain Architecture Graphical

D. Odom, A. Tanay, S. Henderson, 2015 .