Jian Yu

发表

The effect of stromal cell-derived factor-1α/heparin coating of biodegradable vascular grafts on the recruitment of both endothelial and smooth muscle progenitor cells for accelerated regeneration.

Jian Yu, Aijun Wang, Zhenyu Tang, 2012, Biomaterials.

The transcriptional targets of p53 in apoptosis control.

Jian Yu, Lin Zhang, Lin Zhang, 2005, Biochemical and biophysical research communications.

The outer membrane protein Tp92 of Treponema pallidum induces human mononuclear cell death and IL‐8 secretion

Jian Yu, T. Zeng, F. Zhao, 2018, Journal of cellular and molecular medicine.

Apoptosis in human cancer cells

Jian Yu, Lin Zhang, 2004, Current opinion in oncology.

Landscape perspectives of tumor, EMT, and development

Jian Yu, Qiong Liu, Chong Yu, 2019, Physical biology.

Aurora Kinase Inhibition Induces PUMA via NF-κB to Kill Colon Cancer Cells

Jian Yu, Lin Zhang, C. Dudgeon, 2014, Molecular Cancer Therapeutics.

Lactobacillus reuteri Releasing IL-22 (LR-IL-22) Facilitates Intestinal Radioprotection for Whole-Abdomen Irradiation (WAI) of Ovarian Cancer

Hong Wang, Jian Yu, M. Huq, 2022, Radiation Research.

Ionizing irradiation induces acute haematopoietic syndrome and gastrointestinal syndrome independently in mice

Jian Yu, Lin Zhang, J. Greenberger, 2014, Nature Communications.

IGF-1 induces hypoxia-inducible factor 1α-mediated GLUT3 expression through PI3K/Akt/mTOR dependent pathways in PC12 cells

Jian Yu, Guangyi Jiang, Shan-yi Zhang, 2012, Brain Research.

Lung adenocarcinoma with EGFR amplification has distinct clinicopathologic and molecular features in never-smokers.

M. Loda, A. Iafrate, P. Jänne, 2009, Cancer research.

Crizotinib Induces PUMA-Dependent Apoptosis in Colon Cancer Cells

Jian Yu, Lin Zhang, Xingnan Zheng, 2013, Molecular Cancer Therapeutics.

Neuroprotective effect of chondroitinase ABC on primary and secondary brain injury after stroke in hypertensive rats

Jian Yu, Xin-ran Chen, Jin-sheng Zeng, 2014, Brain Research.

NSAIDs Downregulate Bcl-XL and Dissociate BAX and Bcl-XL to Induce Apoptosis in Colon Cancer Cells

Jian Yu, Lin Zhang, Alexander Bank, 2008, Nutrition and cancer.

PUMA-mediated epithelial cell apoptosis promotes Helicobacter pylori infection-mediated gastritis

Jian Yu, Guoxin Zhang, Yanhong Gu, 2020, Cell Death & Disease.

Mcl-1 Phosphorylation without Degradation Mediates Sensitivity to HDAC Inhibitors by Liberating BH3-Only Proteins.

Jian Yu, Lin Zhang, Z. Nikolovska-Coleska, 2018, Cancer research.

Cirmtuzumab Blocks Wnt5a/ROR1-Stimulation Of NF-κB To Repress Autocrine STAT3-Activation In Chronic Lymphocytic Leukemia.

Emanuela M. Ghia, K. Messer, L. Rassenti, 2019, Blood.

Differential Apoptotic Response to the Proteasome Inhibitor Bortezomib (VELCADETM, PS-341) in Bax-Deficient and p21-Deficient Colon Cancer Cells

Jian Yu, Lin Zhang, P. Steiner, 2003, Cancer biology & therapy.

Hsp90 Inhibitors Promote p53-Dependent Apoptosis through PUMA and Bax

Jian Yu, Lin Zhang, Xingnan Zheng, 2013, Molecular Cancer Therapeutics.

Second-generation Probiotics Producing IL-22 Increase Survival of Mice After Total Body Irradiation

Jian Yu, Hong Wang, P. Wipf, 2019, In Vivo.

Downregulation of Dkk3 activates beta-catenin/TCF-4 signaling in lung cancer.

Jian Yu, J. Siegfried, S. Dacic, 2008, Carcinogenesis.

Role of Smac in Determining the Chemotherapeutic Response of Esophageal Squamous Cell Carcinoma

Jian Yu, Q. Zhan, Xiaohang Zhao, 2011, Clinical Cancer Research.

Cancer Therapy : Preclinical Role of Smac in Determining the Chemotherapeutic Response of Esophageal Squamous Cell Carcinoma

Jian Yu, Q. Zhan, Xiaohang Zhao, 2011 .

FVIIa prevents the progressive hemorrhaging of a brain contusion by protecting microvessels via formation of the TF–FVIIa–FXa complex

Jian Yu, Xing Wu, Q. Yuan, 2017, Neuroscience.

Galectin-9: A Suppressor of Atherosclerosis?

Jian Yu, R. Zhu, Kunwu Yu, 2020, Frontiers in Immunology.

PUMA amplifies necroptosis signaling by activating cytosolic DNA sensors

Jian Yu, D. Stolz, Lin Zhang, 2018, Proceedings of the National Academy of Sciences.

Cancer Biology and Signal Transduction Aurora Kinase Inhibition Induces Puma via Nf-kb to Kill Colon Cancer Cells

Jian Yu, Lin Zhang, C. Dudgeon, 2022 .

p53 Up‐regulated Modulator of Apoptosis Induction Mediates Acetaminophen‐Induced Necrosis and Liver Injury in Mice

Jian Yu, Lin Zhang, W. Ding, 2019, Hepatology.

PUMA Induction by FoxO3a Mediates the Anticancer Activities of the Broad-Range Kinase Inhibitor UCN-01

Jian Yu, Lin Zhang, C. Dudgeon, 2010, Molecular Cancer Therapeutics.

LYMPHOID NEOPLASIA MicroRNA-155 in ﬂ uences B-cell receptor signaling and associates with aggressive disease in chronic lymphocytic leukemia

Emanuela M. Ghia, K. Messer, C. Croce, 2014 .

Immunogenic effects of chemotherapy-induced tumor cell death

Jian Yu, Lin Zhang, Yi-Jun Wang, 2018, Genes & diseases.

SMAC mimetics sensitize nonsteroidal anti-inflammatory drug-induced apoptosis by promoting caspase-3-mediated cytochrome c release.

Jian Yu, Lin Zhang, Chunying Du, 2008, Cancer research.

Targeting Myc-driven stress vulnerability in mutant KRAS colorectal cancer

Jian Yu, Lujia Chen, Xinghua Lu, 2022, Molecular Biomedicine.

Immunogenic cell death in colon cancer prevention and therapy

Jian Yu, Lin Zhang, H. Ruan, 2020, Molecular carcinogenesis.

Circ_0027089 regulates NACC1 by targeting miR-136-5p to aggravate the development of hepatitis B virus-related hepatocellular carcinoma

Jian Yu, Wei He, Xing-Yang Zhu, 2021, Anti-cancer drugs.

Mcl-1 Degradation Is Required for Targeted Therapeutics to Eradicate Colon Cancer Cells.

Jian Yu, Lin Zhang, Z. Nikolovska-Coleska, 2017, Cancer research.

No PUMA, no death: implications for p53-dependent apoptosis.

Jian Yu, Lin Zhang, 2003, Cancer cell.

PUMA mediates the apoptotic response to p53 in colorectal cancer cells

K. Kinzler, B. Vogelstein, Jian Yu, 2003, Proceedings of the National Academy of Sciences of the United States of America.

BET Inhibitors Potentiate Chemotherapy and Killing of SPOP-Mutant Colon Cancer Cells via Induction of DR5.

Jian Yu, R. Schoen, Lin Zhang, 2019, Cancer research.

Restoring PUMA induction overcomes KRAS-mediated resistance to anti-EGFR antibodies in colorectal cancer

Jian Yu, A. Bardelli, Lin Zhang, 2018, Oncogene.

FBW7-Dependent Mcl-1 Degradation Mediates the Anticancer Effect of Hsp90 Inhibitors

Jian Yu, Lin Zhang, Z. Nikolovska-Coleska, 2017, Molecular Cancer Therapeutics.

Following cytochrome c release, autophagy is inhibited during chemotherapy-induced apoptosis by caspase 8-mediated cleavage of Beclin 1.

Jian Yu, D. Stolz, Lin Zhang, 2011, Cancer research.

Inhibition of multiple CDKs potentiates colon cancer chemotherapy via p73-mediated DR5 induction

Jian Yu, Lin Zhang, J. Tong, 2023, Oncogene.

Elevation of receptor tyrosine kinase EphA2 mediates resistance to trastuzumab therapy.

Lu Xie, Carlos Arteaga, Dana M. Brantley-Sieders, 2010, Cancer research.

BH3 mimetics to improve cancer therapy; mechanisms and examples.

Jian Yu, Lin Zhang, Lin Zhang, 2007, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

Abstract 667: Regorafenib inhibits colorectal tumor growth through PUMA-mediated apoptosis

Jian Yu, Lin Zhang, Dongshi Chen, 2015 .

BET protein degradation triggers DR5-mediated immunogenic cell death to suppress colorectal cancer and potentiate immune checkpoint blockade

Jian Yu, Shaomeng Wang, Lin Zhang, 2021, Oncogene.

BID mediates selective killing of APC-deficient cells in intestinal tumor suppression by nonsteroidal antiinflammatory drugs

Jian Yu, R. Schoen, Lin Zhang, 2014, Proceedings of the National Academy of Sciences.

TAp73 promotes cell survival upon genotoxic stress by inhibiting p53 activity

Jian Yu, Lin Zhang, Ye Peng, 2014, Oncotarget.

Uncoupling p53 Functions in Radiation-Induced Intestinal Damage via PUMA and p21

Jian Yu, Lin Zhang, W. Qiu, 2011, Molecular Cancer Research.

Development of small-molecule PUMA inhibitors for mitigating radiation-induced cell death.

Ivet Bahar, Ahmet Bakan, Michael Epperly, 2011, Current topics in medicinal chemistry.

Deletion of Puma protects hematopoietic stem cells and confers long-term survival in response to high-dose gamma-irradiation.

Jian Yu, Lin Zhang, G. Zambetti, 2008, Blood.

BRAFV600E-dependent Mcl-1 stabilization leads to everolimus resistance in colon cancer cells

Jian Yu, Lin Zhang, Xiang-yun Li, 2016, Oncotarget.

PUMA Dissociates Bax and Bcl-XL to Induce Apoptosis in Colon Cancer Cells*

Peng Wang, Alexander Bank, Jian Yu, 2006, Journal of Biological Chemistry.

PUMA Sensitizes Lung Cancer Cells to Chemotherapeutic Agents and Irradiation

Jian Yu, Lin Zhang, W. Yue, 2006, Clinical Cancer Research.

MicroRNA-638 inhibits cell proliferation, invasion and regulates cell cycle by targeting tetraspanin 1 in human colorectal carcinoma

Jian Yu, Yuan Yin, W. Guo, 2014, Oncotarget.

M6A “Writer” Gene METTL14: A Favorable Prognostic Biomarker and Correlated With Immune Infiltrates in Rectal Cancer

Jian Yu, Shanshan Liu, Xinwen Wang, 2021, Frontiers in Oncology.

Immunotherapy efficacy on mismatch repair-deficient colorectal cancer: From bench to bedside.

Jian Yu, Lin Zhang, Suisui Hao, 2020, Biochimica et biophysica acta. Reviews on cancer.

PUMA suppresses intestinal tumorigenesis in mice.

Jian Yu, Lin Zhang, W. Qiu, 2009, Cancer research.

Chemoprevention by nonsteroidal anti-inflammatory drugs eliminates oncogenic intestinal stem cells via SMAC-dependent apoptosis

Jian Yu, H. Clevers, N. Barker, 2010, Proceedings of the National Academy of Sciences.

PUMA–mediated apoptosis drives chemical hepatocarcinogenesis in mice

Jian Yu, Wancai Yang, Lin Zhang, 2011, Hepatology.

Necroptosis: an alternative cell death program defending against cancer.

Jian Yu, Lin Zhang, Dongshi Chen, 2016, Biochimica et biophysica acta.

Fibulin-5 inhibits Wnt/β-catenin signaling in lung cancer

Jian Yu, Lin Zhang, Z. Yao, 2015, Oncotarget.

Fibulin-5 suppresses lung cancer invasion by inhibiting matrix metalloproteinase-7 expression.

Jian Yu, J. Siegfried, Lin Zhang, 2009, Cancer research.

Colorectal cancer prevention: Immune modulation taking the stage.

Jian Yu, R. Schoen, Lin Zhang, 2018, Biochimica et biophysica acta. Reviews on cancer.

Co-targeting translation and proteasome rapidly kills colon cancer cells with mutant RAS/RAF via ER stress

Jian Yu, Lin Zhang, W. Qiu, 2016, Oncotarget.

tRF3008A suppresses the progression and metastasis of colorectal cancer by destabilizing FOXK1 in an AGO-dependent manner

Jian Yu, Shanshan Liu, Xinwen Wang, 2022, Journal of experimental & clinical cancer research : CR.

A coordinated action of Bax, PUMA, and p53 promotes MG132-induced mitochondria activation and apoptosis in colon cancer cells

Jian Yu, Lin Zhang, Xiao-Ming Yin, 2007, Molecular Cancer Therapeutics.

The nuclear function of p53 is required for PUMA-mediated apoptosis induced by DNA damage

Jian Yu, Lin Zhang, Peng Wang, 2007, Proceedings of the National Academy of Sciences.

Administration of PUMA adenovirus increases the sensitivity of esophageal cancer cells to anticancer drugs

Jian Yu, Q. Zhan, M. Fu, 2006, Cancer biology & therapy.

Synthetical lethality of Werner helicase and mismatch repair deficiency is mediated by p53 and PUMA in colon cancer

Jian Yu, Lin Zhang, P. Opresko, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation

Linheng Li, Jian Yu, Lin Zhang, 2015, Scientific Reports.

Fibulin-3 suppresses Wnt/β-catenin signaling and lung cancer invasion.

Jian Yu, Lin Zhang, Z. Yao, 2014, Carcinogenesis.

Growth factors protect intestinal stem cells from radiation-induced apoptosis by suppressing PUMA through the PI3K/AKT/p53 axis

Jian Yu, Lin Zhang, W. Qiu, 2009, Oncogene.

Smac Modulates Chemosensitivity in Head and Neck Cancer Cells through the Mitochondrial Apoptotic Pathway

Jian Yu, Lin Zhang, Quanhong Sun, 2011, Clinical Cancer Research.

The Multi-Targeted Kinase Inhibitor Sunitinib Induces Apoptosis in Colon Cancer Cells via PUMA

Jian Yu, Lin Zhang, C. Dudgeon, 2012, PloS one.

microRNA-21 negatively regulates Cdc25A and cell cycle progression in colon cancer cells.

Zhenghe Wang, Peng Wang, John S Lazo, 2009, Cancer research.

Expression of a recombinant FLT3 ligand and its emtansine conjugate as a therapeutic candidate against acute myeloid leukemia cells with FLT3 expression

Jian Yu, Z. Zhao, Yihang Pan, 2021, Microbial Cell Factories.

eIF4E S209 phosphorylation licenses myc- and stress-driven oncogenesis

N. Sonenberg, Jian Yu, Lujia Chen, 2020, eLife.

DNA Damage and Cellular Stress Responses Uncoupling p 53 Functions in Radiation-Induced Intestinal Damage via PUMA and p 21

Jian Yu, Lin Zhang, W. Qiu, 2011 .

Progression in Colon Cancer Cells microRNA-21 Negatively Regulates Cdc 25 A and Cell Cycle

A. Dulak, Jian Yu, Lin Zhang, 2009 .

Molecular Cancer apeutics apeutic Discovery A Induction by FoxO 3 a Mediates the Anticancer ivities of the Broad-Range Kinase Ther bitor UCN-01

Jian Yu, Lin Zhang, Quanhong Sun, 2010 .

Sp1 and p73 activate PUMA following serum starvation.

Jian Yu, Lin Zhang, T. Sakaida, 2008, Carcinogenesis.

mTOR inhibitors induce apoptosis in colon cancer cells via CHOP-dependent DR5 induction upon 4E-BP1 dephosphorylation

Jian Yu, Lin Zhang, Xingnan Zheng, 2015, Oncogene.

Frequent Inactivation of RAMP2, EFEMP1 and Dutt1 in Lung Cancer by Promoter Hypermethylation

Jian Yu, J. Siegfried, S. Dacic, 2007, Clinical Cancer Research.

Role of Apoptosis in Colon Cancer Biology, Therapy, and Prevention

Jian Yu, Lin Zhang, 2013, Current Colorectal Cancer Reports.

Targeting Myc-driven stress addiction in colorectal cancer.

Jian Yu, Lin Zhang, B. Leibowitz, 2023, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

XRCC1 genetic polymorphism Arg339Gln, Arg194Trp, Arg280His and gastric cancer risk: an evidence based decision.

Jian Yu, Jian Yu, Hong Shen, 2014, Cancer biomarkers : section A of Disease markers.

p53 and PUMA independently regulate apoptosis of intestinal epithelial cells in patients and mice with colitis.

Jian Yu, Lin Zhang, N. Chandel, 2011, Gastroenterology.

PUMA regulates intestinal progenitor cell radiosensitivity and gastrointestinal syndrome.

Jian Yu, Lin Zhang, G. Zambetti, 2008, Cell stem cell.

p53 independent induction of PUMA mediates intestinal apoptosis in response to ischaemia–reperfusion

Jian Yu, Lin Zhang, G. Zambetti, 2006, Gut.

Correction: Co-targeting translation and proteasome rapidly kills colon cancer cells with mutant RAS/RAF via ER stress

Jian Yu, W. Qiu, Xiang-yun Li, 2018, Oncotarget.

Ferredoxin reductase affects p53-dependent, 5-fluorouracil–induced apoptosis in colorectal cancer cells

K. Kinzler, B. Vogelstein, Jian Yu, 2001, Nature Medicine.

Analysis of human transcriptomes

G. Landes, A. Lash, K. Kinzler, 1999, Nature Genetics.

Mutations of mitotic checkpoint genes in human cancers

Bert Vogelstein, Kenneth W. Kinzler, Christoph Lengauer, 1998, Nature.

PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and mice.

Jian Yu, M. Regueiro, R. Schoen, 2011, The Journal of clinical investigation.

Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis

Jian Yu, N. Arnheim, R. Flavell, 1995, Cell.

Large-scale cDNA transfection screening for genes related to cancer development and progression.

Jian Yu, Jianren Gu, J. Yu, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Influence of Induced Reactive Oxygen Species in p53-Mediated Cell Fate Decisions

Sam W. Lee, Jian Yu, S. Aaronson, 2003, Molecular and Cellular Biology.

Cell-cycle arrest versus cell death in cancer therapy

Bert Vogelstein, K. Kinzler, B. Vogelstein, 1997, Nature Medicine.

Inhibiting oncogenic signaling by sorafenib activates PUMA via GSK3β and NF-κB to suppress tumor cell growth

Jian Yu, Lin Zhang, C. Dudgeon, 2011, Oncogene.

Downregulation of Dkk3 activates β-catenin/TCF-4 signaling in lung cancer

Jian Yu, J. Siegfried, S. Dacic, 2008 .

Ferredoxin reductase affects p53-dependent, 5-fluorouracil–induced apoptosis in colorectal cancer cells

K. Kinzler, B. Vogelstein, Jian Yu, 2001, Nature Medicine.

Non-steroidal anti-inflammatory drugs induce immunogenic cell death in suppressing colorectal tumorigenesis

Jian Yu, D. Stolz, R. Ferris, 2021, Oncogene.

PUMA overexpression induces reactive oxygen species generation and proteasome-mediated stathmin degradation in colorectal cancer cells.

Jian Yu, Jian Yu, K. Liu, 2005, Cancer research.

Intestinal Radiation Protection and Mitigation by Second-Generation Probiotic Lactobacillus-reuteri Engineered to Deliver Interleukin-22

Hong Wang, Jian Yu, D. Stolz, 2022, International journal of molecular sciences.

Interferon b drives intestinal regeneration after radiation

Jian Yu, Lujia Chen, Xinghua Lu, 2021, Science advances.

Cleaving Beclin 1 to suppress autophagy in chemotherapy-induced apoptosis

Jian Yu, Lin Zhang, Hua Li, 2011, Autophagy.

Intestinal stem cell injury and protection during cancer therapy.

Jian Yu, J. Yu, 2013, Translational cancer research.

Dual inhibition of BET and HAT/p300 suppresses colorectal cancer via DR5- and p53/PUMA-mediated cell death

Jian Yu, F. Dai, Lin Zhang, 2022, Frontiers in Oncology.

mTOR inhibition suppresses Myc-driven polyposis by inducing immunogenic cell death

Jian Yu, Lin Zhang, Guangyi Zhao, 2023, Oncogene.

MLH1 Deficiency Induces Cetuximab Resistance in Colon Cancer via Her‐2/PI3K/AKT Signaling

Jian Yu, Shanshan Liu, Xinwen Wang, 2020, Advanced science.

Selection against PUMA Gene Expression in Myc-Driven B-Cell Lymphomagenesis

Mark A. Hall, Jian Yu, J. Sample, 2008, Molecular and Cellular Biology.

DEC1 is a downstream target of TGF-β with sequence-specific transcriptional repressor activities

K. Kinzler, B. Vogelstein, Jian Yu, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Overexpression of proline oxidase induces proline-dependent and mitochondria-mediated apoptosis

C. Obie, D. Valle, Jian Yu, 2006, Molecular and Cellular Biochemistry.

Role of Receptor Interacting Protein (RIP) kinases in cancer

Jian Yu, Lin Zhang, Jianqing J. Yu, 2021, Genes & diseases.

Transcriptional Regulation of Apoptosis

Jian Yu, Lin Zhang, C. Dudgeon, 2009 .

Genomic signatures reveal DNA damage response deficiency in colorectal cancer brain metastases

Hongbing Shen, Jian Yu, Zhibin Hu, 2019, Nature Communications.

Targeting p53-dependent stem cell loss for intestinal chemoprotection

Jian Yu, R. Schoen, Lin Zhang, 2018, Science Translational Medicine.

Mitochondrial signaling in cell death via the Bcl-2 family

Jian Yu, J. Yu, B. Leibowitz, 2010, Cancer biology & therapy.

SMAC/Diablo-dependent apoptosis induced by nonsteroidal antiinflammatory drugs (NSAIDs) in colon cancer cells.

K. Kinzler, B. Vogelstein, Jian Yu, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Mcl-1 inhibition overcomes intrinsic and acquired regorafenib resistance in colorectal cancer

Jian Yu, R. Schoen, Lin Zhang, 2020, Theranostics.

SMAC IAP Addiction in Cancer

Jian Yu, J. Yu, Matthew F Brown, 2013 .

Studying human mutations by sperm typing: instability of CAG trinucleotide repeats in the human androgen receptor gene

Jian Yu, N. Arnheim, Lin Zhang, 1994, Nature Genetics.

Mitotic CDK1 and 4E-BP1 I: Loss of 4E-BP1 serine 82 phosphorylation promotes proliferative polycystic disease and lymphoma in aged or sublethally irradiated mice

Jian Yu, U. Chandran, A. Chakka, 2023, PloS one.

Release of Interferon-β (IFN-β) from Probiotic Limosilactobacillus reuteri-IFN-β (LR-IFN-β) Mitigates Gastrointestinal Acute Radiation Syndrome (GI-ARS) following Whole Abdominal Irradiation

Hong Wang, Jian Yu, J. Greenberger, 2023, Cancers.

The GS-nitroxide JP4-039 improves intestinal barrier and stem cell recovery in irradiated mice

Jian Yu, P. Wipf, Lin Zhang, 2018, Scientific Reports.

Chemosensitization of head and neck cancer cells by PUMA

Jian Yu, J. Yu, S. Gollin, 2007, Molecular Cancer Therapeutics.

Transforming Growth Factor-β Directly Induces p53-up-regulated Modulator of Apoptosis (PUMA) during the Rapid Induction of Apoptosis in Myc-driven B-cell Lymphomas*

Jian Yu, G. Inman, M. Cragg, 2012, The Journal of Biological Chemistry.

Pharmacologic ATM but not ATR kinase inhibition abrogates p21-dependent G1 arrest and promotes gastrointestinal syndrome after total body irradiation

Jian Yu, T. Conrads, M. O’Connor, 2017, Scientific Reports.

SEMCM: A Self-Expressive Matrix Completion Model for Anti-cancer Drug Sensitivity Prediction

Jian Yu, Hui Liu, Lin Zhang, 2022, Current Bioinformatics.

Early Prediction of Cancer Progression by Depth-Resolved Nanoscale Mapping of Nuclear Architecture from Unstained Tissue Specimens.

Shikhar Uttam, Yang Liu, Douglas J Hartman, 2015, Cancer research.

Identification and classification of p 53-regulated genes

K. Kinzler, B. Vogelstein, Jian Yu, 1999 .

Inhibition of CDK4/6 protects against radiation-induced intestinal injury in mice.

Jian Yu, Lin Zhang, J. Greenberger, 2016, The Journal of clinical investigation.

CDX2 is mutated in a colorectal cancer with normal APC/β-catenin signaling

Tong-Chuan He, Bert Vogelstein, Kornelia Polyak, 1999, Oncogene.

PUMA Kills Stem Cells to Stall Cancer?

Jian Yu, J. Yu, 2009, Molecular and cellular pharmacology.

γPNA FRET Pair Miniprobes for Quantitative Fluorescent In Situ Hybridization to Telomeric DNA in Cells and Tissue

Jian Yu, Jian Yu, B. Armitage, 2017, Molecules.

Role of BAX in the apoptotic response to anticancer agents.

K. Kinzler, B. Vogelstein, Jian Yu, 2000, Science.

PUMA induces the rapid apoptosis of colorectal cancer cells.

K. Kinzler, B. Vogelstein, Jian Yu, 2001, Molecular cell.

Identification and classification of p53-regulated genes.

K. Kinzler, B. Vogelstein, Jian Yu, 1999, Proceedings of the National Academy of Sciences of the United States of America.

PUMA, a potent killer with or without p53

Jian Yu, Lin Zhang, L. Zhang, 2008, Oncogene.

Genomic signatures reveal DNA damage response deficiency in colorectal cancer brain metastases

Hongbing Shen, Jian Yu, Zhibin Hu, 2019, Nature Communications.

PUMA mediates EGFR tyrosine kinase inhibitor-induced apoptosis in head and neck cancer cells

Jian Yu, J. Grandis, Z. Chen, 2009, Oncogene.

Loss of Caspase-3 sensitizes colon cancer cells to genotoxic stress via RIP1-dependent necrosis

Jian Yu, Lin Zhang, L. Zhang, 2015, Cell Death and Disease.

Mononucleotide Repeat Sequence Variability in Mismatch Repair-deficient Cancers 1

K. Kinzler, B. Vogelstein, Jian Yu, 2001 .

Multiplex DNA methylation profiling by ARMS-PCR for body fluid identification

Jian Yu, Weibo Liang, Lin Zhang, 2019 .

Short mononucleotide repeat sequence variability in mismatch repair-deficient cancers.

K. Kinzler, B. Vogelstein, Jian Yu, 2001, Cancer research.

Co-targeting translation and proteasome rapidly kills colon cancer cells with mutant RAS/RAF via ER stress

Jian Yu, Lin Zhang, W. Qiu, 2016, OncoTarget.

Inhibition of CDK4/6 protects against radiation-induced intestinal injury in mice.

Jian Yu, Lin Zhang, J. Greenberger, 2016, Journal of Clinical Investigation.

An apoptosis-independent role of SMAC in tumor suppression

Jian Yu, Hong Wang, Lin Zhang, 2013, Oncogene.

FBW7 mutations mediate resistance of colorectal cancer to targeted therapies by blocking Mcl-1 degradation

Jian Yu, Lin Zhang, L. Zhang, 2016, Oncogene.

PUMA is directly activated by NF-κB and contributes to TNF-α-induced apoptosis

Jian Yu, Lin Zhang, C. Dudgeon, 2009, Cell Death and Differentiation.

Targeting Bax interaction sites reveals that only homo-oligomerization sites are essential for its activation

Jian Yu, Lin Zhang, L. Zhang, 2013, Cell Death and Differentiation.