L. Piazzi

发表

Extensive SAR and computational studies of 3-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2H-2-chromenone (AP2238) derivatives.

A. Cavalli, V. Andrisano, L. Piazzi, 2007, Journal of medicinal chemistry.

Design, synthesis, and evaluation of benzophenone derivatives as novel acetylcholinesterase inhibitors.

A. Cavalli, L. Piazzi, F. Belluti, 2009, European journal of medicinal chemistry.

Multi-target-directed coumarin derivatives: hAChE and BACE1 inhibitors as potential anti-Alzheimer compounds.

A. Cavalli, V. Andrisano, L. Piazzi, 2008, Bioorganic & medicinal chemistry letters.

Benzofuran-based hybrid compounds for the inhibition of cholinesterase activity, beta amyloid aggregation, and abeta neurotoxicity.

V. Andrisano, L. Piazzi, A. Bisi, 2008, Journal of medicinal chemistry.

Homopterocarpanes as bridged triarylethylene analogues: synthesis and antagonistic effects in human MCF-7 breast cancer cells.

L. Piazzi, F. Belluti, A. Bisi, 2005, Farmaco.

Mono- or di-fluorinated analogues of flavone-8-acetic acid: synthesis and in vitro biological activity.

L. Piazzi, F. Belluti, A. Bisi, 2005, Anticancer research.

Protolytic properties of polyamine wasp toxin analogues studied by 13C NMR spectroscopy

L. Piazzi, J. Jaroszewski, K. Strømgaard, 2006, Magnetic resonance in chemistry : MRC.

New derivatives of xanthenone-4-acetic acid: synthesis, pharmacological profile and effect on TNF-alpha and NO production by human immune cells.

L. Piazzi, F. Belluti, A. Bisi, 2006, Bioorganic & medicinal chemistry.

Complementary medicinal chemistry-driven strategies toward new antitrypanosomal and antileishmanial lead drug candidates.

A. Cavalli, L. Piazzi, F. Belluti, 2010, FEMS immunology and medical microbiology.

Synthesis and biological evaluation of 3-alkoxy analogues of flavone-8-acetic acid.

L. Piazzi, F. Belluti, A. Bisi, 2003, Journal of medicinal chemistry.

1,4-Dihydropyridine derivatives as calcium channel modulators: the role of 3-methoxy-flavone moiety.

L. Piazzi, F. Belluti, A. Bisi, 2005, Bioorganic & medicinal chemistry.

Targeting Alzheimer's disease: Novel indanone hybrids bearing a pharmacophoric fragment of AP2238.

Silvia Gobbi, Maurizio Recanatini, Andrea Cavalli, 2010, Bioorganic & medicinal chemistry.

3-(4-[[Benzyl(methyl)amino]methyl]phenyl)-6,7-dimethoxy-2H-2-chromenone (AP2238) inhibits both acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation: a dual function lead for Alzheimer's disease therapy.

A. Cavalli, V. Andrisano, L. Piazzi, 2003, Journal of medicinal chemistry.

Lead optimization providing a series of flavone derivatives as potent nonsteroidal inhibitors of the cytochrome P450 aromatase enzyme.

A. Cavalli, L. Piazzi, F. Belluti, 2006, Journal of medicinal chemistry.

Enantioselective nonsteroidal aromatase inhibitors identified through a multidisciplinary medicinal chemistry approach.

Silvia Gobbi, Maurizio Recanatini, Andrea Cavalli, 2005, Journal of medicinal chemistry.

New potent P-glycoprotein inhibitors carrying a polycyclic scaffold.

L. Piazzi, F. Belluti, A. Bisi, 2006, Journal of medicinal chemistry.

Imidazolylmethylbenzophenones as highly potent aromatase inhibitors.

Silvia Gobbi, Maurizio Recanatini, Andrea Cavalli, 2007, Journal of medicinal chemistry.

Acetylcholinesterase inhibitors: SAR and kinetic studies on omega-[N-methyl-N-(3-alkylcarbamoyloxyphenyl)methyl]aminoalkoxyaryl derivatives.

A. Cavalli, V. Andrisano, V. Cavrini, 2001, Journal of medicinal chemistry.

SAR of 9-amino-1,2,3,4-tetrahydroacridine-based acetylcholinesterase inhibitors: synthesis, enzyme inhibitory activity, QSAR, and structure-based CoMFA of tacrine analogues.

A. Cavalli, V. Andrisano, V. Cavrini, 2000, Journal of medicinal chemistry.

Cholinesterase inhibitors: xanthostigmine derivatives blocking the acetylcholinesterase-induced beta-amyloid aggregation.

A. Cavalli, V. Andrisano, L. Piazzi, 2005, Journal of medicinal chemistry.

From the dual function lead AP2238 to AP2469, a multi-target-directed ligand for the treatment of Alzheimer's disease

V. Andrisano, L. Piazzi, M. Bartolini, 2014, Pharmacology research & perspectives.

Design, Synthesis and Structure—Activity Relationships of a Phenotypic Small Library against Protozoan Infections

Maria Paola Costi, L. Piazzi, F. Belluti, 2017 .

Development of a Focused Library of Triazole‐Linked Privileged‐Structure‐Based Conjugates Leading to the Discovery of Novel Phenotypic Hits against Protozoan Parasitic Infections

Maria Paola Costi, L. Piazzi, F. Belluti, 2018, ChemMedChem.

Cholinesterase inhibitors: SAR and enzyme inhibitory activity of 3-[omega-(benzylmethylamino)alkoxy]xanthen-9-ones.

V. Andrisano, L. Piazzi, F. Belluti, 2007, Bioorganic & medicinal chemistry.